Cardiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 17.
No Gender Gap Found for Clot-Busting Drug
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Title: No Gender Gap Found for Clot-Busting DrugCategory: Health NewsCreated: 11/9/2009 4:10:00 PMLast Editorial Review: 11/10/2009
Source: MedicineNet Heart General - November 10, 2009 Category: Cardiology Source Type: consumer
Doctors Spending More Time Now With PatientsEmail this article to a colleague.
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Title: Doctors Spending More Time Now With PatientsCategory: Health NewsCreated: 11/9/2009 4:10:00 PMLast Editorial Review: 11/10/2009
Source: MedicineNet High Blood Pressure General - November 10, 2009 Category: Cardiology Source Type: consumer
Volcano Corporation Presentation at Canaccord Adams Conference to Be WebcastEmail this article to a colleague.
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Volcano Corporation (Nasdaq: VOLC), a leader in the development, manufacture and sales of products for the diagnosis and treatment of coronary and peripheral artery disease, said today that it will be participating in the Third Annual Canaccord Cardiovascular Conference on Tuesday, November 10.
Source: News from Angioplasty.Org - November 10, 2009 Category: Cardiology Source Type: news
Pseudo-Ventricular Over and Under-Sensing during an Episode of Double Tachycardia. What is the Mechanism?Email this article to a colleague.
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Source: Pacing and Clinical Electrophysiology : PACE - November 10, 2009 Category: Cardiology Authors: DARDO E. FERRARA, MIKHAEL F. EL-CHAMI Source Type: journals
CVN: NiacinEmail this article to a colleague.
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Heart Minute: Niacin Decreases Carotid Disease
Source: Cardiosource - November 10, 2009 Category: Cardiology Source Type: organizations
Misleading Results of Randomized Trials: The Example of Renal Artery StentingEmail this article to a colleague.
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Source: The Journal of Clinical Hypertension - November 10, 2009 Category: Cardiology Authors: Samuel J. Mann, Thomas A. Sos Source Type: journals
Incidence of Myocardial Infarction or Stroke or Death at 47-Month Follow-Up in Patients With Diabetes and a Predicted Exercise Capacity ≤85% vs >85% During an Exercise Treadmill Sestamibi Stress TestEmail this article to a colleague.
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A treadmill exercise sestamibi stress test (TESST) was performed in 609 consecutive diabetic persons with a mean age of 70 years and no history of coronary artery disease (CAD) who were referred for a TESST because of chest pain or dyspnea. Of 609 patients, 301 (49%) had a predicted exercise capacity [le]85% (group A) and 308 (51%) had a predicted exercise capacity >85% (group B). Group A patients had a higher prevalence of myocardial ischemia (43% vs 30%, P=.0005), 2- or 3-vessel obstructive CAD (38% vs 18%, P=.001), myocardial infarction (17% vs 9%, P=.004), death (10% vs 4%, P=.008), and myocardial infarction or stroke ...
Source: Preventive Cardiology - November 10, 2009 Category: Cardiology Authors: Bredy Pierre-Louis, Wilbert S. Aronow, Joo H. Yoon, Chul Ahn, Albert J. DeLuca, Melvin B. Weiss, Kumar Kalapatapu, Anthony L. Pucillo, Craig E. Monsen Source Type: journals
Images in cardiovascular medicine. Cardiac CT assessment of prosthetic aortic valve dysfunction secondary to acute thrombosis and response to thrombolysis.Email this article to a colleague.
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PMID: 19901204 [PubMed - in process]
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Chan J, Marwan M, Schepis T, Ropers D, Du L, Achenbach S Tags: Circulation Source Type: journals
Left atrial appendage occlusion does not eliminate the need for warfarin.Email this article to a colleague.
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PMID: 19901203 [PubMed - in process]
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Whitlock RP, Healey JS, Connolly SJ Tags: Circulation Source Type: journals
Left atrial appendage occlusion eliminates the need for warfarin.Email this article to a colleague.
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PMID: 19901202 [PubMed - in process]
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Holmes DR, Schwartz RS Tags: Circulation Source Type: journals
Letter by Brown and Pretorius regarding article, "effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients".Email this article to a colleague.
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PMID: 19901200 [PubMed - in process]
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Brown NJ, Pretorius M Tags: Circulation Source Type: journals
Images in cardiovascular medicine. Adventitial fibromuscular dysplasia of the renal artery: management challenges of nonatherosclerotic renal artery stenosis.Email this article to a colleague.
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PMID: 19901199 [PubMed - in process]
Source: Circulation - November 10, 2009 Category: Cardiology Authors: Weiner RB, Kiernan TJ, Yan BP, Rosenfield K, Jaff MR Tags: Circulation Source Type: journals
Transseptal Dispersion of Repolarization and Its Role in the Development of Torsade de Pointes ArrhythmiasEmail this article to a colleague.
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Conclusions: Our data indicate that dispersion of repolarization across the interventricular septum is twice that of the LV free wall, predisposing to development of TdP under long-QT conditions. Our findings suggest that the coronary-perfused ventricular septal preparation may be a sensitive model in which to assess the potential arrhythmogenic effects of drugs and pathophysiological conditions. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7)
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: SERGE SICOURI, AARON GLASS, MARCELA FERREIRO, CHARLES ANTZELEVITCH Source Type: journals
Results of Short-Term and Long-Term Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation Using Duty-Cycled Bipolar and Unipolar Radiofrequency EnergyEmail this article to a colleague.
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Conclusion: PV isolation by duty-cycled unipolar/bipolar RF ablation can be effectively and safely performed with a circular, decapolar catheter. Twelve-month follow-up data compare favorably with early postablation results, indicating stable effects over time. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]7)
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: MARCUS WIECZOREK, REINHARD HOELTGEN, ELVAN AKIN, ALI REZA SALILI, HAKAN ORAL, FRED MORADY Source Type: journals
Impact of Tricuspid Regurgitation and Prior Coronary Bypass Surgery on the Geometry of the Coronary Sinus: A Rotational Coronary Angiography StudyEmail this article to a colleague.
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The objective of this study was to examine the impact of the underlying cardiac pathology on the variability of the CS anatomy, using rotational coronary venous angiography (RCVA). Methods and Results: Seventy-nine patients undergoing RCVA for cardiac resynchronization therapy (CRT) were evaluated: age 63 ± 15 years, 43% with prior coronary artery bypass grafting (CABG). Aspects of the CS anatomy which could impact cannulation were examined: the CS ostial angle, the posterior displacement of the CS away from the atrioventricular groove, a measure of CS curvature, and the presence of stenoses and aneurysmal dilatations. Th...
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: DAN BLENDEA, E. KEVIN HEIST, SAUMYA DAS, STEPHAN DANIK, CONOR BARRETT, THEOFANIE MELA, JEREMY N. RUSKIN, JAGMEET P. SINGH Source Type: journals
The Disparities in the Electrogram Voltage Measurement During Atrial Fibrillation and Sinus RhythmEmail this article to a colleague.
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Conclusion: The peak electrogram unipolar voltage during AF did not represent the voltage during SR. The RMS amplitude may be an alternative metric for voltage mapping to characterize the myocardial substrate. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6)
Source: Journal of Cardiovascular Electrophysiology - November 10, 2009 Category: Cardiology Authors: CHIEN-JUNG CHANG, YENN-JIANG LIN, SATOSHI HIGA, SHIH-LIN CHANG, LI-WEI LO, TA-CHUAN TUAN, YU-FENG HU, AMEYA R. UDYAVAR, WEI-HUA TANG, WEN-CHIN TSAI, SHIN-YU HUANG, NGUYEN-HUU TUNG, KAZUYOSHI SUENARI, HSUAN-MING TSAO, SHIH-ANN CHEN Source Type: journals
Efficacy and safety of 2-years treatment with ambrisentan for pulmonary arterial hypertensionEmail this article to a colleague.
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Source: J Am Coll Cardiol
Area: News
The ARIES-1 (Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies) and ARIES-2 trials were the 12-week, placebo-controlled studies that led to the regulatory approval of ambrisentan for the treatment of pulmonary arterial hypertension (PAH). Two year data from these studies have been published in the Journal of the American College of Cardiology.
The studies, and the subsequent long-term extension protocol, ARIES-E study, involved 383 patients who received ambrisentan (2.5, 5, or 10 mg). After 2 years of ...
Source: NeLM - Cardiovascular Medicine - November 10, 2009 Category: Cardiology Source Type: organizations
Thiazide diuretics in hypertension - review of the last 50 yearsEmail this article to a colleague.
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Source: Arch Internal Med
Area: News
Thiazide diuretics have been used in the treatment of hypertension for over 50 years: this narrative review summarises their use and some of the major trials that provided the evidence of their efficacy.
The authors, one of whom was involved in the initial clinical use of these drugs, briefly describe the early development and introduction of the first thiazide (chlorothiazide) in the late 1950's, with the first clinical report of use for hypertension being published in 1958. Despite this long history of use, while the physiological consequences are known, the exact mechanis...
Source: NeLM - Cardiovascular Medicine - November 10, 2009 Category: Cardiology Source Type: organizations
ROADMAP: ARB reduces microalbuminuria in Type 2 diabetesEmail this article to a colleague.
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Findings from the ROADMAP trial suggest that the angiotensin receptor blocker olmesartan delayed or prevented the onset of microalbuminuria in patients with Type 2 diabetes.
Source: MedWire News - Cardiology - November 10, 2009 Category: Cardiology Source Type: news
Expert Opinion: Overcoming the Barriers to Stem Cell TherapyEmail this article to a colleague.
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Source: Cardiosource - November 10, 2009 Category: Cardiology Source Type: organizations
Big People May Wind Up with Big Hearts (CME/CE)Email this article to a colleague.
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Obesity may be the leading risk factor for an enlarged left atrium as patients get older, researchers said.
Source: MedPage Today Cardiovascular - November 9, 2009 Category: Cardiology Source Type: news
Clopidogrel Benefit Roughly Equal for Women and Men (CME/CE)Email this article to a colleague.
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Unlike aspirin, clopidogrel (Plavix) appears to work about as well in women as it does in men, according to a large meta-analysis.
Source: MedPage Today Cardiovascular - November 9, 2009 Category: Cardiology Source Type: news
Journal Scan: Assessment of Coronary Plaque Progression in Coronary Computed Tomography Angiography Using a Semiquantitative Score (JACC Cardiovasc Imaging 2009;2:1262-1270.)Email this article to a colleague.
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CTAs were performed using identical protocols 2 years apart in 69 patients with chest pain, but no evidence of acute coronary syndrome. CTAs were blindly analyzed, in 1 mm thick cross-sections at 1 mm increments, for CAP in the left main and proximal 40 mm of the left anterior descending, circumflex. . .
Source: Cardiosource - November 9, 2009 Category: Cardiology Source Type: organizations
Early Abciximab Has Benefits in High-Risk STEMI Patients: StudyEmail this article to a colleague.
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Giving abciximab to high-risk patients with ST-elevation myocardial infarction (STEMI) before transferring them for percutaneous coronary intervention (PCI) reduces 1-year mortality without increasing bleeding complications, new research shows. Reuters Health Information
Source: Medscape Cardiology Headlines - November 9, 2009 Category: Cardiology Tags: Cardiology Source Type: info
CRT benefit in mild HF shown by REVERSE 2-year dataEmail this article to a colleague.
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Cardiac resynchronization therapy is associated with improved clinical outcomes and reduced left ventricular dimensions in heart failure patients in New York Heart Association functional classes I or II, show 2-year results for the European cohort in REVERSE.
Source: MedWire News - Heart Failure - November 9, 2009 Category: Cardiology Source Type: news
Albumin excretion linked with BP in normoalbuminuric diabetic patientsEmail this article to a colleague.
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Urinary albumin excretion is correlated with blood pressure (BP) and glycemic control in normoalbuminuric patients with Type 2 diabetes, a large study has demonstrated.
Source: MedWire News - Hypertension - November 9, 2009 Category: Cardiology Source Type: news
House delivers healthcare reform victory in late-night sessionEmail this article to a colleague.
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Democrats in the U.S. House of Representatives managed to squeak out a healthcare reform victory (220-215) late Saturday evening, after ratifying the Stupak-Pitts Amendment that will prohibit abortion funding for both the public option and affordability credits.
Source: Cardiovascular Business News - November 9, 2009 Category: Cardiology Tags: Latest News Source Type: news
AHA's 2009 Women In Cardiology Mentoring Award To Be Presented To C. Noel Bairey Merz, M.D.,Email this article to a colleague.
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C. Noel Bairey Merz, M.D., an internationally recognized authority on women's heart health, will receive the American Heart Association's 2009 Women in Cardiology Mentoring Award at the organization's Scientific Sessions 2009, to be held in Orlando at the Orange County Convention Center Nov. 14-Nov. 18. Bairey Merz is director of the Women's Heart Center and the Preventive and Rehabilitative Cardiac Center at the Cedars-Sinai Heart Institute.
Source: Cardiovascular / Cardiology News From Medical News Today - November 9, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
Association Between Higher Carotid Arterial Stenting Rates And Poorer Clinical OutcomesEmail this article to a colleague.
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Among eligible Medicare beneficiaries, increased use of carotid arterial stenting (CAS) procedures to treat carotid stenosis - the narrowing of the carotid artery - is associated with higher rates of mortality and adverse clinical outcomes, including heart attack and stroke, according to researchers from the University of Pennsylvania School of Medicine.
Source: Cardiovascular / Cardiology News From Medical News Today - November 9, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
Study Finds Less Than 1 In 3 Toronto Bystanders Who Witness A Cardiac Arrest Try To HelpEmail this article to a colleague.
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Researchers at St. Michael's Hospital working in conjunction with EMS services, paramedics and fire services across Ontario found that a bystander who attempts cardiopulmonary resuscitation (CPR) can quadruple the survival rate to over 50 per cent. But Dr. Laurie Morrison and the research team at Rescu have found only 30 per cent of bystanders in Toronto are willing to help, one of the lowest rates of bystanders helping others in the developed world.
Source: Cardiovascular / Cardiology News From Medical News Today - November 9, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
Enrollment In Study On Resuscitation Methods For Cardiac Arrest Stopped By NHLBIEmail this article to a colleague.
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Enrollment has ended early in a large, multicenter clinical trial comparing two distinct resuscitation strategies delivered by emergency medical service (EMS) providers to increase blood flow during cardiac arrest. The study's independent monitoring board and the National Heart, Lung, and Blood Institute (NHLBI), the lead sponsor of the study, stopped enrollment based on preliminary data suggesting that neither strategy significantly improved survival.
Source: Cardiovascular / Cardiology News From Medical News Today - November 9, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
Can a Bad Boss Make You Sick?Email this article to a colleague.
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Title: Can a Bad Boss Make You Sick?Category: Health NewsCreated: 11/6/2009 12:10:00 PMLast Editorial Review: 11/9/2009
Source: MedicineNet Cholesterol General - November 9, 2009 Category: Cardiology Source Type: consumer
Breastfeeding Benefits Moms and Babies: ReportEmail this article to a colleague.
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Title: Breastfeeding Benefits Moms and Babies: ReportCategory: Health NewsCreated: 11/6/2009 2:10:00 PMLast Editorial Review: 11/9/2009
Source: MedicineNet Cholesterol General - November 9, 2009 Category: Cardiology Source Type: consumer
Can a Bad Boss Make You Sick?Email this article to a colleague.
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Title: Can a Bad Boss Make You Sick?Category: Health NewsCreated: 11/6/2009 12:10:00 PMLast Editorial Review: 11/9/2009
Source: MedicineNet Heart General - November 9, 2009 Category: Cardiology Source Type: consumer
Breastfeeding Benefits Moms and Babies: ReportEmail this article to a colleague.
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Title: Breastfeeding Benefits Moms and Babies: ReportCategory: Health NewsCreated: 11/6/2009 2:10:00 PMLast Editorial Review: 11/9/2009
Source: MedicineNet High Blood Pressure General - November 9, 2009 Category: Cardiology Source Type: consumer
Asasantin Retard (dipyridamole 200 mg and aspirin 25 mg) - Revised SPCEmail this article to a colleague.
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Source: eMC (electronic Medicines Compendium)
Area: Other Library Updates > SPC Changes
Revised SPC, includes change to: Section 4.4 (Special Warnings and Special Precautions for Use) - A small number of cases have been reported in which unconjugated dipyridamole was shown to be incorporated into gallstones to a variable extent (up to 70% by dry weight of stone). These patients were all elderly, had evidence of ascending cholangitis and had been treated with oral dipyridamole for a number of years. There is no evidence that dipyridamole was the initiating factor in causing gallstones to form in these patients. It is possi...
Source: NeLM - Cardiovascular Medicine - November 9, 2009 Category: Cardiology Source Type: organizations
CVN: New ResourcesEmail this article to a colleague.
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New Resources on Cardiosource
Source: Cardiosource - November 9, 2009 Category: Cardiology Source Type: organizations
Evidence of benefit with aspirin for prophylaxis in people with diabetes is uncertainEmail this article to a colleague.
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Source: BMJ
Area: News
A meta-analysis of trial data found that in people with diabetes, there was no unequivocal evidence of benefit for primary prevention with low-dose aspirin in reducing major cardiovascular events. The evidence on harms was inconsistent.
Low-dose aspirin is generally recommended in guidelines as primary prevention of major cardiovascular events in people with diabetes, although this is based mainly on extrapolation of the results of trials in other high-risk populations. There is limited evidence relating directly to people with diabetes. The aim of this meta-analysis was to identify trial...
Source: NeLM - Cardiovascular Medicine - November 9, 2009 Category: Cardiology Source Type: organizations
Combined home/GP education strategy reduces hypertension in PakistanEmail this article to a colleague.
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Family-based home health education coupled with educating general practitioners on hypertension led to significant blood pressure reductions among patients with hypertension in Pakistan.
Source: MedWire News - Cardiology - November 9, 2009 Category: Cardiology Source Type: news
No clear benefit of aspirin for primary CV prevention in diabetesEmail this article to a colleague.
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Results from a meta-analysis published in the British Medical Journal show no clear benefit of aspirin therapy for primary prevention of cardiovascular events in individuals with diabetes.
Source: MedWire News - Cardiology - November 9, 2009 Category: Cardiology Source Type: news
Heart Rate Recovery and Chronotropic Incompetence in Patients with Subclinical HypothyroidismEmail this article to a colleague.
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Conclusion:The results of the present study demonstrated that SCH can cause impaired cardiovascular autonomic function and attenuated HR response to exercise. (PACE 2009; 1[ndash]4)
Source: Pacing and Clinical Electrophysiology : PACE - November 9, 2009 Category: Cardiology Authors: MUSTAFA AKCAKOYUN, YUNUS EMIROGLU, SELCUK PALA, RAMAZAN KARGIN, GAMZE BABUR GULER, OZLEM ESEN, HEKIM KARAPINAR, BIROL SAY, ALI METIN ESEN Source Type: journals
Drug–Drug NoninteractionsEmail this article to a colleague.
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Understanding and documentation of drug[ndash]drug interactions (DDIs) are an important component of drug development, and of clinical therapeutics. Because clinical DDI studies are costly, time-consuming, and involve some risk, not all clinical DDI questions can be realistically addressed through human DDI trials. In vitro models have been used to identify and predict drug combinations that might interact, and combinations that are unlikely to interact. This screening or "filtration" information allows clinical resources to be targeted in a more informed way. Still, many DDI studies will end up with a negative result. Neg...
Source: Cardiovascular Therapeutics - November 9, 2009 Category: Cardiology Authors: David J. Greenblatt Tags: EDITORIAL Source Type: journals
Bridging of Chronic Oral Anticoagulation with Enoxaparin in Patients with Atrial Fibrillation: Results from the Prospective BRAVE RegistryEmail this article to a colleague.
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Current American College of Chest Physicians (ACCP) guidelines on the perioperative management of oral anticoagulation (OAC) suggest bridging therapy with therapeutic doses of low-molecular-weight heparin (LMWH) in patients with atrial fibrillation (AF) if at high or moderate thromboembolic (TE) risk, and with reduced doses in patients with low TE risk. Our objective was to assess the efficacy and safety of bridging OAC with enoxaparin in AF patients. These are the results of an open, prospective monocenter register. Hospitalized and ambulatory patients with AF requiring bridging therapy at high or moderate TE risk and nor...
Source: Cardiovascular Therapeutics - November 9, 2009 Category: Cardiology Authors: C. Hammerstingl, A. Schmitz, R. Fimmers, H. Omran Tags: RESEARCH Source Type: journals
Effects of Laropiprant, a Selective Prostaglandin D2 Receptor 1 Antagonist, on the Pharmacokinetics of RosiglitazoneEmail this article to a colleague.
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Laropiprant (LRPT), a prostaglandin D2 receptor-1 antagonist shown to reduce niacin-induced flushing symptoms, has been combined with niacin for treatment of dyslipidemia. This open-label, randomized, 2-period crossover study assessed the pharmacokinetics of single-dose rosiglitazone in the presence and absence of multiple-dose LRPT. Twelve healthy male and female subjects, 34[ndash]64 years of age, received two, once-daily oral treatments in random sequence separated by [ge]3-day washout: (1) multiple-dose LRPT 40 mg/day for 7 days (Days 1 to 7) coadministered with single-dose rosiglitazone 4 mg on Day 6; (2) single-dose ...
Source: Cardiovascular Therapeutics - November 9, 2009 Category: Cardiology Authors: Jules I. Schwartz, Mark Stroh, Bing Gao, Fang Liu, Kimberly Rosko, Stefan Zajic, Alan J. Meehan, Jon Ruckle, Eseng Lai, John A. Wagner Tags: RESEARCH Source Type: journals
Gender and Responses to Aspirin and Clopidogrel: Insights Using Short ThrombelastographyEmail this article to a colleague.
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There is significant variability in both baseline clotting tendency and response to antiplatelet therapy. Responses are associated with outcome. We have investigated whether differences could explain the increased risk observed in women presenting with coronary artery disease. We have utilized short thrombelastography to assess (i) baseline clotting responses, (ii) response to aspirin and clopidogrel, and (iii) post-treatment platelet reactivity in 48 young volunteers, 22 older patients and 18 patients with previous stent thrombosis. Baseline responses were significantly higher in young women than in men. While there was n...
Source: Cardiovascular Therapeutics - November 9, 2009 Category: Cardiology Authors: Alex R. Hobson, Zeshan Qureshi, Phil Banks, Nick Curzen Tags: RESEARCH Source Type: journals
Ability of Amiodarone and Propranolol Alone or in Combination to Prevent Post-coronary Bypass Atrial FibrillationEmail this article to a colleague.
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Atrial fibrillation (AF) is the most common arrhythmia in coronary artery bypass grafting (CABG) patients. The purpose of this study was to determine the best prophylaxis for AF prior to CABG. In this double-blind randomized study, 240 consecutive patients underwent elective CABG. They were then divided randomly into three groups to receive propranolol (n = 80), amiodarone (n = 80), or both drugs (n = 80). All groups received their medications from preoperative day 7 to post-CABG day 5. The patients were well matched for age, sex, risk factors, comorbidities, ejection fraction, and cardioplegic technique. Post-CABG AF deve...
Source: Cardiovascular Therapeutics - November 9, 2009 Category: Cardiology Authors: Javad Kojuri, Yadollah Mahmoodi, Mansoor Jannati, Masih Shafa, Mohammad Ghazinoor, Mahammad Bagher Sharifkazemi Tags: RESEARCH Source Type: journals
Regenerative Therapy in Peripheral Artery DiseaseEmail this article to a colleague.
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Patients with peripheral artery disease (PAD) and critical limb ischemia are the main candidates for limb amputations and have a poor life expectancy. Frequently, these patients are not eligible for either surgical or percutaneous interventions aimed at mechanical revascularization. Therefore, new strategies need to be identified to offer these patients a viable therapeutic option. Gene and cell therapy hold great promise for the treatment of peripheral vascular diseases because, in animal models, local delivery of growth factors and endothelial progenitor cells result in new blood vessel formation and regeneration of isch...
Source: Cardiovascular Therapeutics - November 9, 2009 Category: Cardiology Authors: Antonia Germani, Cristiana Di Campli, Giulio Pompilio, Paolo Biglioli, Maurizio C. Capogrossi Tags: REVIEWS Source Type: journals
Compliance With the Treatment of Hypertension: The Potential of Combination TherapyEmail this article to a colleague.
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J Clin Hypertens (Greenwich). Patient adherence to antihypertensive medication is vital to ensure the successful treatment of hypertension. Low levels of adherence to and persistence with prescribed therapy are major factors leading to the current poor rates of blood pressure control among patients with hypertension. There are many reasons for nonadherence to therapy including patient-, physician-, and therapy-related factors. Poor tolerability has a detrimental effect on adherence, therefore reducing the apparent effectiveness of agents with dose-dependent side effects. Various effective combination therapies are recommen...
Source: The Journal of Clinical Hypertension - November 9, 2009 Category: Cardiology Authors: Serap Erdine Source Type: journals
Impact of Chronic Aspirin and Statin Therapy on Presentation of Patients With Acute Myocardial Infarction and Impaired Renal FunctionEmail this article to a colleague.
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Chronic use of aspirin and statins has been associated with reduced risk of subsequent myocardial infarction (MI). However, in patients with chronic kidney disease (CKD), the cardioprotective role of aspirin and statins seems to be reduced. To evaluate the impact of chronic aspirin and statin use on clinical presentation of acute MI according to renal function, the authors retrospectively analyzed 595 consecutive patients admitted to our hospital for acute MI. Renal function was normal in 404 patients and impaired in 191. Patients on therapy (113 patients) were less likely to have ST-segment elevation MI (STEMI) compared w...
Source: Preventive Cardiology - November 9, 2009 Category: Cardiology Authors: Alessandro Sciahbasi, Romano Arcieri, Maria Quarto, Gianluca Pendenza, Chiara Lanzillo, Francesco Summaria, Enrico Romagnoli, Cosimo Commisso, Maria Penco, Ernesto Lioy Source Type: journals
Heart Rate Predicts Outcomes in an Implantable Cardioverter-Defibrillator Population.Email this article to a colleague.
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Conclusions-In this ICD population, the mean intrinsic HR was strongly associated with outcomes. Clinical Trial Registration-http://www.clinicaltrials.gov. Identifier: NCT00148967.
PMID: 19901194 [PubMed - as supplied by publisher]
Source: Circulation - November 9, 2009 Category: Cardiology Authors: Ahmadi-Kashani M, Kessler DJ, Day J, Bunch TJ, Stolen KQ, Brown S, Sbaity S, Olshansky B, Tags: Circulation Source Type: journals
