Cardiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.
Comparison of Dual Source Computed Tomography Versus Intravascular Ultrasound for Evaluation of Coronary Arteries at Least One Year After Cardiac Transplantation
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In conclusion, DSCT permits the investigation of transplant recipients concerning the presence of CAV with good image quality and high diagnostic accuracy.
Source: The American Journal of Cardiology - November 5, 2009 Category: Cardiology Authors: Tiziano Schepis, Stephan Achenbach, Michael Weyand, Philip Raum, Mohamed Marwan, Tobias Pflederer, Werner G. Daniel, Rene Tandler, Markus Kondruweit, Dieter Ropers Tags: Coronary Artery Disease Source Type: journals
Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human HeartEmail this article to a colleague.
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Conclusions: These findings are the first to directly investigate the effects of type 2 diabetes on a panoply of mitochondrial functions in the human myocardium using cellular and molecular approaches, and they show that mitochondria in diabetic human hearts have specific impairments in maximal capacity to oxidize fatty acids and glutamate, yet increased mitochondrial H2O2 emission, providing insight into the role of mitochondrial dysfunction and oxidative stress in the pathogenesis of heart failure in diabetic patients.
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Ethan J. Anderson, Alan P. Kypson, Evelio Rodriguez, Curtis A. Anderson, Eric J. Lehr, P. Darrell Neufer Tags: Diabetes and Cardiac Function Source Type: journals
Giant True Saphenous Vein Graft AneurysmEmail this article to a colleague.
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A 60-year-old man who had undergone saphenous vein grafting to the left anterior descending artery 23 years ago complained of continuous resting chest pain for the last 48 h. No electrocardiographic changes were observed, and laboratory tests showed normal troponin T and creatine kinase levels on admittance and at 8, 12, and 24 h later. Coronary angiography was performed and showed chronic total occlusion of the left anterior descending artery and a severely degenerated and occluded saphenous vein graft. Contrast-enhanced computed tomography showed an extracardiac mass of 85 × 51 mm compressing the left atrium, correspond...
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Juan Garcia-Lara, Eduardo Pinar-Bermudez, Jose Antonio Hurtado, Mariano Valdez-Chavarri Tags: IMAGES IN CARDIOLOGY Source Type: journals
The 5-Year Clinical Outcomes After a Randomized Comparison of Sirolimus-Eluting Versus Bare-Metal Stent Implantation in Patients With ST-Segment Elevation Myocardial InfarctionEmail this article to a colleague.
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Because patients with acute ST-segment elevation myocardial infarction (STEMI) were excluded from early randomized trials, only relatively short-term data from large multicenter studies comparing drug-eluting stents (DES) with bare-metal stents (BMS) are currently available. Unambiguous ascertainment of long-term compliance with thienopyridines is problematic in STEMI, which is a matter of serious concern (), and one observational registry suggested higher late (>6 months) unadjusted and adjusted mortality rates in STEMI patients with a DES compared with those with a BMS (). Thus, the use of a DES in STEMI patients still r...
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Matteo Tebaldi, Chiara Arcozzi, Gianluca Campo, Gianfranco Percoco, Roberto Ferrari, Marco Valgimigli, STRATEGY Investigators Tags: Research Correspondence Source Type: journals
CorrectionEmail this article to a colleague.
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Yang Q, Li K, Liu X, et al. Contrast-Enhanced Whole-Heart Coronary Magnetic Resonance Angiography at 3.0-T: A Comparative Study With X-Ray Angiography in a Single Center. J Am Coll Cardiol 2009;54:69–76.
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Tags: CORRECTIONS Source Type: journals
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Meyers DG, Neuberger JS, He J. Cardiovascular Effect of Bans on Smoking in Public Places: A Systematic Review and Meta-Analysis. J Am Coll Cardiol 2009;54:1249–55. In this article, the meta-analysis included data from Pueblo, Colorado, which the authors erroneously reported as incidence rate ratio (IRR): 0.30. Actually, the IRR is 0.66 (95% confidence interval [CI]: 0.58 to 0.75). This changes the meta-analysis summary IRR to 0.92 (95% CI: 0.86 to 0.99). The meta-regression of the effect of ban duration also changes. The coefficient of post-ban duration in the meta-regression model is −0.16 (95% CI: −0.20 to −0.11...
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Tags: CORRECTIONS Source Type: journals
Inside This IssueEmail this article to a colleague.
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1827 Franz H. Messerli, Gurusher S. Panjrath
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Plasma Concentration of Amino-Terminal Pro-Brain Natriuretic Peptide in Chronic Heart Failure: Prediction of Cardiovascular Events and Interaction With the Effects of Rosuvastatin: A Report From CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure)Email this article to a colleague.
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Conclusions: Patients with heart failure due to ischemic heart disease who have NT-proBNP values
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: John G.F. Cleland, John J.V. McMurray, John Kjekshus, Jan H. Cornel, Peter Dunselman, Cândida Fonseca, Åke Hjalmarson, Jerzy Korewicki, Magnus Lindberg, Naresh Ranjith, Dirk J. van Veldhuisen, Finn Waagstein, Hans Wedel, John Wikstrand, CORONA Study Gro Tags: Heart Failure Source Type: journals
Can Natriuretic Peptides Help Identify Heart Failure Patients for Whom Statins Are Beneficial?⁎Email this article to a colleague.
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One of the great success stories in cardiology is the ability of statins to improve the prognosis in patients at risk of a first or subsequent cardiovascular event. This benefit has been shown across a wide spectrum of patient profiles. The efficacy of statin therapy has been challenged only in high-risk patients such as those on dialysis (), older patients with systolic heart failure (), and patients with chronic heart failure of any cause ().
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Lori B. Daniels, Elizabeth Barrett-Connor Tags: Heart Failure: Editorial Comment Source Type: journals
Aortic Valve Replacement: A Prospective Randomized Evaluation of Mechanical Versus Biological Valves in Patients Ages 55 to 70 YearsEmail this article to a colleague.
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Conclusions: At 13 years, patients undergoing aortic valve replacement either with MP or BP valves had a similar survival rate as well the same rate of occurrence of thromboembolism, bleeding, endocarditis, and MAPE, but patients who had undergone aortic valve replacement with BP valves faced a significantly higher risk of valve failure and reoperation.
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Paolo Stassano, Luigi Di Tommaso, Mario Monaco, Francesco Iorio, Paolo Pepino, Nicola Spampinato, Carlo Vosa Tags: Valvular Heart Disease Source Type: journals
Current Selection of Optimal Prosthetic Aortic Valve Replacement in Middle-Aged Patients: Still Dealer's Choice⁎Email this article to a colleague.
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Selection of the type of prosthetic aortic valve replacement (AVR) is frequently a difficult judgment decision affecting the majority of patients who require surgical AVR. The choices generally include bioprosthetic valves (stented or stentless porcine bioprosthesis, stented pericardial prosthesis) and mechanical prosthetic valves (bileaflet or monoleaflet) (). Mechanical valves have the advantage of structural stability but the disadvantage of requiring anticoagulation with warfarin, whereas bioprostheses have the advantage of not requiring anticoagulation with warfarin but the disadvantage of being subject to time-relate...
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Peter H. Stone Tags: Valvular Heart Disease: Editorial Comment Source Type: journals
The Coronary Artery Calcium Score and Stress Myocardial Perfusion Imaging Provide Independent and Complementary Prediction of Cardiac RiskEmail this article to a colleague.
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Conclusions: The CACS and SPECT findings are independent and complementary predictors of short- and long-term cardiac events. Despite a normal SPECT result, a severe CACS identifies subjects at high long-term cardiac risk. After a normal SPECT result, our findings support performing a CACS in patients who are at intermediate or high clinical risk for coronary artery disease to better define those who will have a high long-term risk for adverse cardiac events.
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Su Min Chang, Faisal Nabi, Jiaqiong Xu, Leif E. Peterson, Arup Achari, Craig M. Pratt, John J. Mahmarian Tags: Cardiac Imaging Source Type: journals
Structural Abnormalities of the Pulmonary Trunk in Tetralogy of Fallot and Potential Clinical Implications: A Morphological StudyEmail this article to a colleague.
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Conclusions: Marked histological abnormalities in the PT of hearts with TOF exist compared with controls. These changes were present from infancy and among patients who had undergone palliative or reparative surgery, although operations in this cohort were performed late. Our data suggest that structural abnormalities of the PT, similar to these recently shown in the aorta, are intrinsic.
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Elisabeth Bédard, Karen P. McCarthy, Konstantinos Dimopoulos, Georgios Giannakoulas, Michael A. Gatzoulis, Siew Yen Ho Tags: Congenital Heart Disease Source Type: journals
The J-Curve Between Blood Pressure and Coronary Artery Disease or Essential Hypertension: Exactly How Essential?Email this article to a colleague.
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The topic of the J-curve relationship between blood pressure and coronary artery disease (CAD) has been the subject of much controversy for the past decades. An inverse relationship between diastolic pressure and adverse cardiac ischemic events (i.e., the lower the diastolic pressure the greater the risk of coronary heart disease and adverse outcomes) has been observed in numerous studies. This effect is even more pronounced in patients with underlying CAD. Indeed, a J-shaped relationship between diastolic pressure and coronary events was documented in treated patients with CAD in most large trials that scrutinized this re...
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Franz H. Messerli, Gurusher S. Panjrath Tags: VIEWPOINT AND COMMENTARY Source Type: journals
Hypertension and the “J-Curve”Email this article to a colleague.
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Elevated blood pressure (BP) is one of the most common preventable causes of premature death worldwide. Approximately 8 million deaths/year (i.e., 14% of all deaths worldwide) are directly attributable to an elevated BP, and with the worldwide prevalence of hypertension predicted to increase by more than 50% by 2025, the magnitude of BP-related death is set to increase further (). Abundant data from randomized clinical trials have confirmed that the therapeutic lowering of BP in hypertensive people substantially reduces the risk of cardiovascular morbidity and mortality, and as a consequence, the routine treatment of hyper...
Source: Journal of the American College of Cardiology - November 5, 2009 Category: Cardiology Authors: Bryan Williams Tags: VIEWPOINT AND COMMENTARY Source Type: journals
Predicting Clinically Unrecognized Coronary Artery Disease: Use of Two-Dimensional EchocardiographyEmail this article to a colleague.
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This article provides an answer. Cardiovascular Ultrasound
Source: Medscape Cardiology Headlines - November 5, 2009 Category: Cardiology Tags: Radiology Source Type: info
Cellular Source Of Most Common Type Of Abnormal Heart Beat Study: Findings Could Point To More Precise Treatments For Atrial FibrillationEmail this article to a colleague.
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While studying how the heart is formed, scientists at the University of Pennsylvania School of Medicine serendipitously found a novel cellular source of atrial fibrillation (AF), the most common type of abnormal heart beat.
Source: Cardiovascular / Cardiology News From Medical News Today - November 5, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
Journal Scan: Sex Differences in Mortality After Acute Myocardial Infarction: Changes From 1994 to 2006 (Arch Intern Med 2009;169:1767-1774. )Email this article to a colleague.
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Data from the National Registry of Myocardial Infarction (NRMI) were used for the present analysis. Temporal trends in MI were examined starting in June 1994 up to December 2006. Hospital case-fatality rates were compared between men and women and between age groups. Patients were excluded if they e. . .
Source: Cardiosource - November 5, 2009 Category: Cardiology Source Type: organizations
New Class Of Molecules May Help Prevent Fatal Complication In Patients With Kidney DiseaseEmail this article to a colleague.
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Researchers at the University of Maryland School of Medicine have made an important discovery about why potassium builds up to dangerous levels in the bloodstream, a relatively common medical problem that affects about eight percent of hospitalized patients. They have identified a new molecular pathway and a new class of molecules responsible for preventing potassium from being excreted normally through the kidney. Their study was just published in the Journal of Clinical Investigation.
Source: Cardiovascular / Cardiology News From Medical News Today - November 5, 2009 Category: Cardiology Tags: Urology / Nephrology Source Type: news
UCLA Researchers Reconstitute Enzyme That Synthesizes Cholesterol Drug LovastatinEmail this article to a colleague.
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Researchers from the UCLA Henry Samueli School of Engineering and Applied Science have for the first time successfully reconstituted in the laboratory the enzyme responsible for producing the blockbuster cholesterol-lowering drug lovastatin. The research, published Oct. 23 in the journal Science, could potentially lead to the development of other compounds with similarly beneficial effects.
Source: Cholesterol News From Medical News Today - November 5, 2009 Category: Cardiology Tags: Statins Source Type: news
Percutaneous pulmonic valve implantationEmail this article to a colleague.
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Opinion statement Surgically placed valve conduits between the right ventricle and pulmonary artery often fail within 10 years. The failure
may be the result of insufficiency, stenosis, or often a combination of the two. Pulmonic valve insufficiency may lead to
right ventricular dilatation, heart failure, arrhythmias, and death. Reoperation requires cardiopulmonary bypass, which may
aggravate an already failing right ventricle, and is associated with a higher risk of death and significant morbidity. Therefore,
percutaneous implantation of a pulmonic valve is an attractive option to improve hemodynamic functi...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Combined PCI and minimally invasive heart valve surgery for high-risk patientsEmail this article to a colleague.
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Opinion statement Combined coronary artery valvular heart disease is a major cause of morbidity and mortality in the adult patient population.
The standard treatment for such disease has been open heart surgery in which coronary artery bypass grafting (CABG) is performed
concurrently with valve surgery using a median sternotomy and cardiopulmonary bypass. With the increasing complexity of patients
referred to surgery, some patients may prove to be poor surgical candidates for combined valve and CABG surgery. In certain
selected patients who fall into this category, valve surgery and percutaneous coronary int...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Update on renin-angiotensin-aldosterone blockade in heart failureEmail this article to a colleague.
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Opinion statement There is convincing evidence that the renin-angiotensin-aldosterone system (RAAS) plays an important role in heart failure
(HF), from the events that result in its inception through advanced disease. In particular, RAAS activation is one of the
major pathways involved in maladaptive cardiac remodeling, a process that results in progressive cardiac dysfunction. Not
surprisingly, strategies targeting the RAAS have substantial benefits in HF. These therapies, which include angiotensin-converting
enzyme inhibitors, angiotensin receptor blockers, and aldosterone receptor antagonists, have emerge...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
The genetics of cardiomyopathy: Genotyping and genetic counselingEmail this article to a colleague.
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Opinion statement Three decades of ongoing research into the identification of genes responsible for both cardiomyopathies and ion channel diseases
has facilitated a progressive understanding of the pathophysiology of inherited arrhythmogenic diseases. Recent discoveries
in the area of genetics promise to significantly change the current clinical practice of cardiology, as rapid advances in
technology and a coincident reduction of costs associated with sequencing have pushed the “translation“ of genomic information
from bench to bedside. In turn, clinicians have at their disposal new tools for more accur...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Obstructive sleep apnea and heart failureEmail this article to a colleague.
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Opinion statement Obstructive sleep apnea (OSA) exerts several effects that may be particularly deleterious in patients with heart failure (HF).
OSA should be considered especially in HF patients who are obese or have the metabolic syndrome, systemic hypertension, or
pulmonary hypertension. HF patients in whom OSA is suspected should undergo a full evaluation by a sleep specialist, including
a polysomnogram, to diagnose OSA and differentiate this disease from central sleep apnea. Those found to have OSA should then
receive continuous positive airway pressure and/or other interventions, and standard disease m...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Mitral valve repair in the treatment of mitral regurgitationEmail this article to a colleague.
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Opinion statement Because there is no proven effective medical therapy for mitral regurgitation (MR), mitral valve repair (MVRpr) is the treatment
of choice for patients with severe primary nonrheumatic MR. A successfully performed and properly timed MVRpr may lead to
a normal lifestyle and life span. The alternative to repair is mitral valve replacement. Although there have been no randomized
trials of repair versus replacement, almost all reported series demonstrate superior outcomes with repair, and current guidelines
clearly prefer MVRpr over mitral valve replacement for patients with nonrheumatic MR.
...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Transcatheter aortic valve implantationEmail this article to a colleague.
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Opinion statement Aortic stenosis is the most important valvular heart disease affecting the elderly population. Surgical aortic valve replacement
is the mainstay of treatment, although a substantial number of patients are considered high risk for surgery. Many of these
patients do not undergo surgery and have poor outcomes from medically treated symptomatic, severe aortic stenosis. Transcatheter
aortic valve implantation (TAVI) provides a promising treatment option for some of these patients. Several devices are under
investigation. The Edwards Sapien valve (Edwards Lifesciences, Irvine, CA) and the CoreVal...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Percutaneous approaches to mitral regurgitationEmail this article to a colleague.
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Opinion statement Percutaneous therapy for mitral repair has emerged over the past several years as an investigational option for treating mitral
regurgitation (MR). A variety of novel methods to treat MR using a percutaneous route have been developed. Most of these approaches
are modifications of surgical techniques, some established and some obscure. The basic surgical approaches to mitral repair
are annuloplasty and leaflet repair. Catheter-based devices mimic or approximate these surgical approaches. MR as a disease
process is heterogeneous, and different therapeutic approaches are needed for different e...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
How to use diuretics in heart failureEmail this article to a colleague.
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Opinion statement Systemic and pulmonary congestion is a central aspect of both acute and chronic heart failure and directly leads to many of
the clinical manifestations of these syndromes. Therefore, diuretic therapy to treat congestion plays a fundamental role in
heart failure management. However, although diuretics are the most common drugs prescribed for heart failure, there is limited
quality evidence to guide their use. Unlike other components of the heart failure armamentarium, such as β-blockers and angiotensin-converting
enzyme inhibitors, diuretics (with the exception of aldosterone antagonists) h...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Will New Anemia Drug Top Current Treatments?Email this article to a colleague.
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Title: Will New Anemia Drug Top Current Treatments?Category: Health NewsCreated: 11/4/2009 4:10:00 PMLast Editorial Review: 11/5/2009
Source: MedicineNet Cholesterol General - November 5, 2009 Category: Cardiology Source Type: consumer
Autonomic Function during Closed Loop Stimulation and Fixed Rate Pacing: Heart Rate Variability Analysis from 24-Hour Holter RecordingsEmail this article to a colleague.
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Discussion: The two main findings of this study were: in all the patients, CLS seems to mimic short-term physiological HRV, although the variability (total power) was lower than that relative to the spontaneous beats; the HRV of the spontaneous beats had an higher LF/HF when the pacemaker was programmed as DDD respect to CLS, consistent with a shift toward sympathetic predominance. (PACE 2009; 1[ndash]6)
Source: Pacing and Clinical Electrophysiology : PACE - November 5, 2009 Category: Cardiology Authors: RAFFAELE QUAGLIONE, GIOVANNI CALCAGNINI, FEDERICA CENSI, FABRIZIO PICCIRILLI, LUCA IANNUCCI, MARCO RAVEGGI, GIANLUCA BIANCALANA, PIETRO BARTOLINI Source Type: journals
Clinical review: Phosphodiesterase-5 inhibitors for pulmonary arterial hypertensionEmail this article to a colleague.
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This article reviews the evidence for their use: its structure is consistent with other articles in the series, and covers:
. The clinical problem
. Pathophysiology and effect of therapy
. Clinical evidence
. Clinical use
. Adverse effects
. Areas of uncertainty
. Guidelines
. Recommendations
Source: NeLM - Cardiovascular Medicine - November 5, 2009 Category: Cardiology Source Type: organizations
Post-traumatic stress disorder independently linked to poor CV health statusEmail this article to a colleague.
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US researchers report that post-traumatic stress disorder was associated with significantly worse cardiovascular health status, independently of objective measures of cardiac function and comorbid depression, in a well-characterized cohort of adults with stable CV disease.
Source: MedWire News - Cardiology - November 5, 2009 Category: Cardiology Source Type: news
ROOBY trial finds poorer 1-year outcomes with off- versus on-pump CABGEmail this article to a colleague.
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Results of the ROOBY trial show patients undergoing coronary artery bypass graft surgery without cardiopulmonary bypass had worse composite clinical outcomes and poorer graft patency at 1 year than patients who underwent conventional on-pump surgery.
Source: MedWire News - Cardiology - November 5, 2009 Category: Cardiology Source Type: news
Slow Pathway Radiofrequency Ablation in Patients with AVNRT: Junctional Rhythm is Less Frequent during Magnetic Navigation Ablation Than with the Conventional TechniqueEmail this article to a colleague.
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Conclusions:Magnetic remote catheter ablation of AVNRT is effective and is associated with less JB than the manual conventional technique. Therefore, JB may not be considered as a mandatory indicator for successful AVNRT ablation with MN system. (PACE 2009; 1[ndash]5)
Source: Pacing and Clinical Electrophysiology : PACE - November 5, 2009 Category: Cardiology Authors: PHILIPPE RICARD, DECEBAL GABRIEL LATCU, KHELIL YAÏCI, NAIMA ZARQANE, NADIR SAOUDI Source Type: journals
MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts.Email this article to a colleague.
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Conclusions: These results reveal striking differences between in vitro and in vivo phenotypes of miR expression, and further suggest that mRNA signatures do not reliably predict either direct miR targets or major miR effects.
PMID: 19893015 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Matkovich SJ, Wang W, Tu Y, Eschenbacher WH, Dorn LE, Condorelli G, Diwan A, Nerbonne JM, Dorn GW Tags: Circ Res Source Type: journals
Structural Heterogeneity in the Ventricular Wall Plays a Significant Role in the Initiation of Stretch-Induced Arrhythmias in Perfused Rabbit Right Ventricular Tissues and Whole Heart Preparations.Email this article to a colleague.
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Conclusions: Global stretches of intermediate strength, rather than intense stretches, created heterogeneous strain (excitation) distributions in the ventricular wall, which can trigger fatal arrhythmias.
PMID: 19893014 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Seo K, Inagaki M, Nishimura S, Hidaka I, Sugimachi M, Hisada T, Sugiura S Tags: Circ Res Source Type: journals
Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor.Email this article to a colleague.
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Conclusions: Our results reveal a novel gender-specific pathway of cardioprotection mediated by ERalpha and its regulation by MEF2 and class II HDACs.
PMID: 19893013 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: van Rooij E, Fielitz J, Sutherland LB, Thijssen VL, Crijns HJ, Dimaio MJ, Shelton J, De Windt LJ, Hill JA, Olson EN Tags: Circ Res Source Type: journals
Resident Intimal Dendritic Cells Accumulate Lipid and Contribute to the Initiation of Atherosclerosis.Email this article to a colleague.
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Conclusions: Induction of hypercholesterolemia in mice triggers rapid ingestion of lipid by resident intimal DCs, which initiate nascent foam cell lesion formation.
PMID: 19893012 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Paulson KE, Zhu SN, Chen M, Nurmohamed S, Jongstra-Bilen J, Cybulsky MI Tags: Circ Res Source Type: journals
Mechanisms of Mechanically Induced Spontaneous Arrhythmias in Acute Regional Ischemia.Email this article to a colleague.
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Conclusions: Mechanically induced membrane depolarizations in the ischemic region are the mechanism by which mechanical activity contributes to both the origin of and substrate for spontaneous arrhythmias under the conditions of acute regional ischemia.
PMID: 19893011 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Jie X, Gurev V, Trayanova N Tags: Circ Res Source Type: journals
Dietary Protein Level Interacts With omega-3 Polyunsaturated Fatty Acid Deficiency to Induce Hypertension.Email this article to a colleague.
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ConclusionsThese results indicate that the hypertension previously attributed to omega-3 fatty acid deficiency is dependent on additional dietary factors, including protein content. Furthermore, this study is the first to plot the establishment of omega-3 fatty acid deficiency hypertension over time.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.198.
PMID: 19893499 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Begg DP, Sinclair AJ, Stahl LA, Garg ML, Jois M, Weisinger RS Tags: Am J Hypertens Source Type: journals
Insomnia and Sleep Duration as Mediators of the Relationship Between Depression and Hypertension Incidence.Email this article to a colleague.
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ConclusionsThese results suggest the hypothesis that treatment of sleep problems in middle-aged individuals suffering from depression could reduce their risk for developing hypertension, and its vascular and cardiac complications.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.202.
PMID: 19893498 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Gangwisch JE, Malaspina D, Posner K, Babiss LA, Heymsfield SB, Turner JB, Zammit GK, Pickering TG Tags: Am J Hypertens Source Type: journals
Association of Depressive Symptoms With All-Cause and Ischemic Heart Disease Mortality in Adults With Self-Reported Hypertension.Email this article to a colleague.
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ConclusionComorbid depressive symptoms are associated with increased all-cause mortality in patients with self-reported HTN.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.199.
PMID: 19893497 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Axon RN, Zhao Y, Egede LE Tags: Am J Hypertens Source Type: journals
Sexual Dimorphism in the Blood Pressure Response to Angiotensin II in Mice After Angiotensin-converting Enzyme Blockade.Email this article to a colleague.
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ConclusionsThese data suggest that there are species and sex-specific differences in the mechanism of the blood pressure response to Ang II, even during ACE inhibition.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.203.
PMID: 19893496 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Venegas-Pont M, Sartori-Valinotti JC, Glover PH, Reckelhoff JF, Ryan MJ Tags: Am J Hypertens Source Type: journals
Abnormalities in Metalloproteinase Pathways and IGF-I Axis: A Link Between Birth Weight, Hypertension, and Vascular Damage in Childhood.Email this article to a colleague.
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ConclusionsIt is possible that the association of fetal programming with elevated risk for vascular and metabolic disease in later life is, at least in part, mediated by perturbations in the MMP pathways.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.200.
PMID: 19893495 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Sesso R, Franco MC Tags: Am J Hypertens Source Type: journals
Racial Disparities in Hypertension Control, but Not Treatment Intensification.Email this article to a colleague.
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ConclusionsIn our study, black patients had poorer hypertension control, and providers were more likely to intensify antihypertensive drugs at visits of black compared with white patients as appropriate. These data suggest that more research is needed to understand racial disparities in hypertension control.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.201.
PMID: 19893494 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Umscheid CA, Gross R, Weiner MG, Hollenbeak CS, Tang SS, Turner BJ Tags: Am J Hypertens Source Type: journals
Fibulin-2 and Fibulin-5 Cooperatively Function to Form the Internal Elastic Lamina and Protect From Vascular Injury.Email this article to a colleague.
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CONCLUSIONS: Fibulin-2 and fibulin-5 cooperatively function to form the IEL during postnatal development by directing the assembly of elastic fibers, and are responsible for maintenance of the adult vessel wall after injury. The DKO mouse will serve as a unique animal model to test the effect of vessel integrity during various pathological insults.
PMID: 19893004 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 5, 2009 Category: Cardiology Authors: Chapman SL, Sicot FX, Davis EC, Huang J, Sasaki T, Chu ML, Yanagisawa H Tags: Arterioscler Thromb Vasc Biol Source Type: journals
CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose Tissue.Email this article to a colleague.
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CONCLUSIONS: CCL5 could participate in the inflammation of obese WAT by recruiting blood monocytes and exerting antiapoptotic properties on WAT macrophages. This specific role of CCL5 on macrophage survival with maintenance of their lipid scavenging function should be taken into account for future therapeutic strategies in obesity-related diseases.
PMID: 19893003 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 5, 2009 Category: Cardiology Authors: Keophiphath M, Rouault C, Divoux A, Clément K, Lacasa D Tags: Arterioscler Thromb Vasc Biol Source Type: journals
Better survival in hospitalized flu patients on statinsEmail this article to a colleague.
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Statin users hospitalized for influenza experienced a 54% lower risk of death compared with patients not taking statins.
Source: theHeart.org - November 4, 2009 Category: Cardiology Source Type: info
