Cardiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 20.
Update on renin-angiotensin-aldosterone blockade in heart failure
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Opinion statement There is convincing evidence that the renin-angiotensin-aldosterone system (RAAS) plays an important role in heart failure
(HF), from the events that result in its inception through advanced disease. In particular, RAAS activation is one of the
major pathways involved in maladaptive cardiac remodeling, a process that results in progressive cardiac dysfunction. Not
surprisingly, strategies targeting the RAAS have substantial benefits in HF. These therapies, which include angiotensin-converting
enzyme inhibitors, angiotensin receptor blockers, and aldosterone receptor antagonists, have emerge...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
The genetics of cardiomyopathy: Genotyping and genetic counselingEmail this article to a colleague.
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Opinion statement Three decades of ongoing research into the identification of genes responsible for both cardiomyopathies and ion channel diseases
has facilitated a progressive understanding of the pathophysiology of inherited arrhythmogenic diseases. Recent discoveries
in the area of genetics promise to significantly change the current clinical practice of cardiology, as rapid advances in
technology and a coincident reduction of costs associated with sequencing have pushed the “translation“ of genomic information
from bench to bedside. In turn, clinicians have at their disposal new tools for more accur...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Obstructive sleep apnea and heart failureEmail this article to a colleague.
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Opinion statement Obstructive sleep apnea (OSA) exerts several effects that may be particularly deleterious in patients with heart failure (HF).
OSA should be considered especially in HF patients who are obese or have the metabolic syndrome, systemic hypertension, or
pulmonary hypertension. HF patients in whom OSA is suspected should undergo a full evaluation by a sleep specialist, including
a polysomnogram, to diagnose OSA and differentiate this disease from central sleep apnea. Those found to have OSA should then
receive continuous positive airway pressure and/or other interventions, and standard disease m...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Mitral valve repair in the treatment of mitral regurgitationEmail this article to a colleague.
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Opinion statement Because there is no proven effective medical therapy for mitral regurgitation (MR), mitral valve repair (MVRpr) is the treatment
of choice for patients with severe primary nonrheumatic MR. A successfully performed and properly timed MVRpr may lead to
a normal lifestyle and life span. The alternative to repair is mitral valve replacement. Although there have been no randomized
trials of repair versus replacement, almost all reported series demonstrate superior outcomes with repair, and current guidelines
clearly prefer MVRpr over mitral valve replacement for patients with nonrheumatic MR.
...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Transcatheter aortic valve implantationEmail this article to a colleague.
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Opinion statement Aortic stenosis is the most important valvular heart disease affecting the elderly population. Surgical aortic valve replacement
is the mainstay of treatment, although a substantial number of patients are considered high risk for surgery. Many of these
patients do not undergo surgery and have poor outcomes from medically treated symptomatic, severe aortic stenosis. Transcatheter
aortic valve implantation (TAVI) provides a promising treatment option for some of these patients. Several devices are under
investigation. The Edwards Sapien valve (Edwards Lifesciences, Irvine, CA) and the CoreVal...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Percutaneous approaches to mitral regurgitationEmail this article to a colleague.
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Opinion statement Percutaneous therapy for mitral repair has emerged over the past several years as an investigational option for treating mitral
regurgitation (MR). A variety of novel methods to treat MR using a percutaneous route have been developed. Most of these approaches
are modifications of surgical techniques, some established and some obscure. The basic surgical approaches to mitral repair
are annuloplasty and leaflet repair. Catheter-based devices mimic or approximate these surgical approaches. MR as a disease
process is heterogeneous, and different therapeutic approaches are needed for different e...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
How to use diuretics in heart failureEmail this article to a colleague.
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Opinion statement Systemic and pulmonary congestion is a central aspect of both acute and chronic heart failure and directly leads to many of
the clinical manifestations of these syndromes. Therefore, diuretic therapy to treat congestion plays a fundamental role in
heart failure management. However, although diuretics are the most common drugs prescribed for heart failure, there is limited
quality evidence to guide their use. Unlike other components of the heart failure armamentarium, such as β-blockers and angiotensin-converting
enzyme inhibitors, diuretics (with the exception of aldosterone antagonists) h...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals
Will New Anemia Drug Top Current Treatments?Email this article to a colleague.
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Title: Will New Anemia Drug Top Current Treatments?Category: Health NewsCreated: 11/4/2009 4:10:00 PMLast Editorial Review: 11/5/2009
Source: MedicineNet Cholesterol General - November 5, 2009 Category: Cardiology Source Type: consumer
Autonomic Function during Closed Loop Stimulation and Fixed Rate Pacing: Heart Rate Variability Analysis from 24-Hour Holter RecordingsEmail this article to a colleague.
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Discussion: The two main findings of this study were: in all the patients, CLS seems to mimic short-term physiological HRV, although the variability (total power) was lower than that relative to the spontaneous beats; the HRV of the spontaneous beats had an higher LF/HF when the pacemaker was programmed as DDD respect to CLS, consistent with a shift toward sympathetic predominance. (PACE 2009; 1[ndash]6)
Source: Pacing and Clinical Electrophysiology : PACE - November 5, 2009 Category: Cardiology Authors: RAFFAELE QUAGLIONE, GIOVANNI CALCAGNINI, FEDERICA CENSI, FABRIZIO PICCIRILLI, LUCA IANNUCCI, MARCO RAVEGGI, GIANLUCA BIANCALANA, PIETRO BARTOLINI Source Type: journals
Clinical review: Phosphodiesterase-5 inhibitors for pulmonary arterial hypertensionEmail this article to a colleague.
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This article reviews the evidence for their use: its structure is consistent with other articles in the series, and covers:
. The clinical problem
. Pathophysiology and effect of therapy
. Clinical evidence
. Clinical use
. Adverse effects
. Areas of uncertainty
. Guidelines
. Recommendations
Source: NeLM - Cardiovascular Medicine - November 5, 2009 Category: Cardiology Source Type: organizations
Post-traumatic stress disorder independently linked to poor CV health statusEmail this article to a colleague.
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US researchers report that post-traumatic stress disorder was associated with significantly worse cardiovascular health status, independently of objective measures of cardiac function and comorbid depression, in a well-characterized cohort of adults with stable CV disease.
Source: MedWire News - Cardiology - November 5, 2009 Category: Cardiology Source Type: news
ROOBY trial finds poorer 1-year outcomes with off- versus on-pump CABGEmail this article to a colleague.
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Results of the ROOBY trial show patients undergoing coronary artery bypass graft surgery without cardiopulmonary bypass had worse composite clinical outcomes and poorer graft patency at 1 year than patients who underwent conventional on-pump surgery.
Source: MedWire News - Cardiology - November 5, 2009 Category: Cardiology Source Type: news
Slow Pathway Radiofrequency Ablation in Patients with AVNRT: Junctional Rhythm is Less Frequent during Magnetic Navigation Ablation Than with the Conventional TechniqueEmail this article to a colleague.
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Conclusions:Magnetic remote catheter ablation of AVNRT is effective and is associated with less JB than the manual conventional technique. Therefore, JB may not be considered as a mandatory indicator for successful AVNRT ablation with MN system. (PACE 2009; 1[ndash]5)
Source: Pacing and Clinical Electrophysiology : PACE - November 5, 2009 Category: Cardiology Authors: PHILIPPE RICARD, DECEBAL GABRIEL LATCU, KHELIL YAÏCI, NAIMA ZARQANE, NADIR SAOUDI Source Type: journals
MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts.Email this article to a colleague.
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Conclusions: These results reveal striking differences between in vitro and in vivo phenotypes of miR expression, and further suggest that mRNA signatures do not reliably predict either direct miR targets or major miR effects.
PMID: 19893015 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Matkovich SJ, Wang W, Tu Y, Eschenbacher WH, Dorn LE, Condorelli G, Diwan A, Nerbonne JM, Dorn GW Tags: Circ Res Source Type: journals
Structural Heterogeneity in the Ventricular Wall Plays a Significant Role in the Initiation of Stretch-Induced Arrhythmias in Perfused Rabbit Right Ventricular Tissues and Whole Heart Preparations.Email this article to a colleague.
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Conclusions: Global stretches of intermediate strength, rather than intense stretches, created heterogeneous strain (excitation) distributions in the ventricular wall, which can trigger fatal arrhythmias.
PMID: 19893014 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Seo K, Inagaki M, Nishimura S, Hidaka I, Sugimachi M, Hisada T, Sugiura S Tags: Circ Res Source Type: journals
Myocyte Enhancer Factor 2 and Class II Histone Deacetylases Control a Gender-Specific Pathway of Cardioprotection Mediated by the Estrogen Receptor.Email this article to a colleague.
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Conclusions: Our results reveal a novel gender-specific pathway of cardioprotection mediated by ERalpha and its regulation by MEF2 and class II HDACs.
PMID: 19893013 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: van Rooij E, Fielitz J, Sutherland LB, Thijssen VL, Crijns HJ, Dimaio MJ, Shelton J, De Windt LJ, Hill JA, Olson EN Tags: Circ Res Source Type: journals
Resident Intimal Dendritic Cells Accumulate Lipid and Contribute to the Initiation of Atherosclerosis.Email this article to a colleague.
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Conclusions: Induction of hypercholesterolemia in mice triggers rapid ingestion of lipid by resident intimal DCs, which initiate nascent foam cell lesion formation.
PMID: 19893012 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Paulson KE, Zhu SN, Chen M, Nurmohamed S, Jongstra-Bilen J, Cybulsky MI Tags: Circ Res Source Type: journals
Mechanisms of Mechanically Induced Spontaneous Arrhythmias in Acute Regional Ischemia.Email this article to a colleague.
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Conclusions: Mechanically induced membrane depolarizations in the ischemic region are the mechanism by which mechanical activity contributes to both the origin of and substrate for spontaneous arrhythmias under the conditions of acute regional ischemia.
PMID: 19893011 [PubMed - as supplied by publisher]
Source: Circulation Research - November 5, 2009 Category: Cardiology Authors: Jie X, Gurev V, Trayanova N Tags: Circ Res Source Type: journals
Dietary Protein Level Interacts With omega-3 Polyunsaturated Fatty Acid Deficiency to Induce Hypertension.Email this article to a colleague.
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ConclusionsThese results indicate that the hypertension previously attributed to omega-3 fatty acid deficiency is dependent on additional dietary factors, including protein content. Furthermore, this study is the first to plot the establishment of omega-3 fatty acid deficiency hypertension over time.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.198.
PMID: 19893499 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Begg DP, Sinclair AJ, Stahl LA, Garg ML, Jois M, Weisinger RS Tags: Am J Hypertens Source Type: journals
Insomnia and Sleep Duration as Mediators of the Relationship Between Depression and Hypertension Incidence.Email this article to a colleague.
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ConclusionsThese results suggest the hypothesis that treatment of sleep problems in middle-aged individuals suffering from depression could reduce their risk for developing hypertension, and its vascular and cardiac complications.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.202.
PMID: 19893498 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Gangwisch JE, Malaspina D, Posner K, Babiss LA, Heymsfield SB, Turner JB, Zammit GK, Pickering TG Tags: Am J Hypertens Source Type: journals
Association of Depressive Symptoms With All-Cause and Ischemic Heart Disease Mortality in Adults With Self-Reported Hypertension.Email this article to a colleague.
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ConclusionComorbid depressive symptoms are associated with increased all-cause mortality in patients with self-reported HTN.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.199.
PMID: 19893497 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Axon RN, Zhao Y, Egede LE Tags: Am J Hypertens Source Type: journals
Sexual Dimorphism in the Blood Pressure Response to Angiotensin II in Mice After Angiotensin-converting Enzyme Blockade.Email this article to a colleague.
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ConclusionsThese data suggest that there are species and sex-specific differences in the mechanism of the blood pressure response to Ang II, even during ACE inhibition.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.203.
PMID: 19893496 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Venegas-Pont M, Sartori-Valinotti JC, Glover PH, Reckelhoff JF, Ryan MJ Tags: Am J Hypertens Source Type: journals
Abnormalities in Metalloproteinase Pathways and IGF-I Axis: A Link Between Birth Weight, Hypertension, and Vascular Damage in Childhood.Email this article to a colleague.
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ConclusionsIt is possible that the association of fetal programming with elevated risk for vascular and metabolic disease in later life is, at least in part, mediated by perturbations in the MMP pathways.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.200.
PMID: 19893495 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Sesso R, Franco MC Tags: Am J Hypertens Source Type: journals
Racial Disparities in Hypertension Control, but Not Treatment Intensification.Email this article to a colleague.
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ConclusionsIn our study, black patients had poorer hypertension control, and providers were more likely to intensify antihypertensive drugs at visits of black compared with white patients as appropriate. These data suggest that more research is needed to understand racial disparities in hypertension control.American Journal of Hypertension 2009; doi:10.1038/ajh.2009.201.
PMID: 19893494 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 5, 2009 Category: Cardiology Authors: Umscheid CA, Gross R, Weiner MG, Hollenbeak CS, Tang SS, Turner BJ Tags: Am J Hypertens Source Type: journals
Fibulin-2 and Fibulin-5 Cooperatively Function to Form the Internal Elastic Lamina and Protect From Vascular Injury.Email this article to a colleague.
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CONCLUSIONS: Fibulin-2 and fibulin-5 cooperatively function to form the IEL during postnatal development by directing the assembly of elastic fibers, and are responsible for maintenance of the adult vessel wall after injury. The DKO mouse will serve as a unique animal model to test the effect of vessel integrity during various pathological insults.
PMID: 19893004 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 5, 2009 Category: Cardiology Authors: Chapman SL, Sicot FX, Davis EC, Huang J, Sasaki T, Chu ML, Yanagisawa H Tags: Arterioscler Thromb Vasc Biol Source Type: journals
CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose Tissue.Email this article to a colleague.
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CONCLUSIONS: CCL5 could participate in the inflammation of obese WAT by recruiting blood monocytes and exerting antiapoptotic properties on WAT macrophages. This specific role of CCL5 on macrophage survival with maintenance of their lipid scavenging function should be taken into account for future therapeutic strategies in obesity-related diseases.
PMID: 19893003 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 5, 2009 Category: Cardiology Authors: Keophiphath M, Rouault C, Divoux A, Clément K, Lacasa D Tags: Arterioscler Thromb Vasc Biol Source Type: journals
Better survival in hospitalized flu patients on statinsEmail this article to a colleague.
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Statin users hospitalized for influenza experienced a 54% lower risk of death compared with patients not taking statins.
Source: theHeart.org - November 4, 2009 Category: Cardiology Source Type: info
Vital Images’ revenue, income slip in Q3Email this article to a colleague.
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Advanced visualization application developer Vital Images posted a downturn in sales and profits in its financial results for the third quarter, which ended Sept. 30.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Vascular Solutions launches updated hemostasis valveEmail this article to a colleague.
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Vascular Solutions has released its Guardian II Hemostasis Valve, which has an ergonomic click-open and click-close design to provide protection during interventions and separation of multiple guidewires and other devices used in the catheterization procedure.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Off-pump CABG shows no benefit over on-pump approach: ROOBY studyEmail this article to a colleague.
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A 2203-patient randomized trial of off-pump vs on-pump CABG surgery found no differences in neuropsychological outcomes and worse overall outcomes for the off-pump group at one-year follow-up.
Source: theHeart.org - November 4, 2009 Category: Cardiology Source Type: info
Johnson & Johnson to lay off about 8,000 employeesEmail this article to a colleague.
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Johnson & Johnson has begun a restructuring initiative, which will eliminate positions in the range of 6 to 7 percent of its global workforce of 120,000 in an effort to cut costs through 2011.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Private payors look to tackle diabetes care, costs through major employersEmail this article to a colleague.
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With 23.6 million Americans currently diagnosed with diabetes, UnitedHealthcare has introduced the Diabetes Health Plan to provide assistance through employers to their diabetic and pre-diabetic staff.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Traditional CABG Edges Off-Pump Approach (CME/CE, with audio)Email this article to a colleague.
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Use of a heart-lung machine during coronary-artery bypass grafting (CABG) doesn't impair outcomes or cognition any more than "off-pump" procedures, according to results of a large randomized trial.
Source: MedPage Today Cardiovascular - November 4, 2009 Category: Cardiology Source Type: news
Oral Antiplatelet Therapy for Acute and Chronic Management of NSTE ACS: Residual Ischemic Risk and Opportunities for ImprovementEmail this article to a colleague.
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Conclusion These considerations suggest that novel therapies with a different mechanism of action, when used in combination with current
antiplatelet agents, may provide more comprehensive inhibition of platelet activation and additional reductions in morbidity
and mortality, potentially without incremental bleeding risk.
Content Type Journal ArticleDOI 10.1007/s10557-009-6204-5Authors
Marc Cohen, Newark Beth Israel Medical Center Division of Cardiology 201 Lyons Avenue at Osborne Terrace Newark NJ 07112 USA
Journal Cardiovascular Drugs and TherapyOnline ISSN 1573-7241Print ISSN 0920-3206
Source: Cardiovascular Drugs and Therapy - November 4, 2009 Category: Cardiology Tags: Cardiovascular Drugs and Therapy Source Type: journals
VELETI in print: Plaque sealing of SVGs a strategy "ahead of its time"?Email this article to a colleague.
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The imaging study was the first to show that stenting a non-flow-limiting stenosis of an SVG may help slow or halt the accelerated atherosclerosis that takes place in these vessels. An accompanying editorial cautions that the study does little more than "infer a trend toward anatomic benefit."
Source: theHeart.org - November 4, 2009 Category: Cardiology Source Type: info
Adding fuel to the J-curve fire; debate is reignitedEmail this article to a colleague.
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More discussion about the J-curve in hypertension is published this week; one expert believes the undue attention being paid to this subject might discourage doctors from treating high blood pressure aggressively.
Source: theHeart.org - November 4, 2009 Category: Cardiology Source Type: info
Trans-fatty acids and nonlipid risk factorsEmail this article to a colleague.
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Abstract Consumption of industrially produced trans-fatty acids (TFA) is associated with substantial risk of coronary heart disease (CHD). The magnitude of this relationship,
as well as emerging associations with end points such as diabetes and sudden cardiac death, cannot be fully explained by the
well-established adverse effects of TFA on serum lipids. We review the evidence for effects of TFA intake on nonlipid risk
factors. Based on evidence from randomized controlled trials, observational studies, animal experiments, and in vitro studies,
these include effects on systemic inflammation, endothelial dysfu...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Omega-3 fatty acids and heart failureEmail this article to a colleague.
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This article reviews recent clinical and experimental evidence on the effect of
n-3 PUFA in coronary heart disease, with particular attention on HF and its pathophysiologic mechanisms.
Content Type Journal ArticleDOI 10.1007/s11883-009-0066-yAuthors
Roberto Marchioli, Consorzio Mario Negri Sud Via Nazionale 66030 Santa Maria Imbaro ItalyMaria Giuseppina SillettaGiacomo LevantesiRaffaella Pioggiarella
Journal Current Atherosclerosis ReportsOnline ISSN 1534-6242Print ISSN 1523-3804
Journal Volume Volume 11
Journal Issue Volume 11, Number 6 / November, 2009
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Impact of circulating esterified eicosanoids and other oxylipins on endothelial functionEmail this article to a colleague.
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Abstract Eicosanoids, including epoxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and other oxylipins derived from polyunsaturated
fatty acids, have emerging roles in endothelial inflammation and subsequent atherosclerosis. Unlike eicosanoids in the prostanoid
series, they are known to be esterified in cell lipids such as phospholipids and triglycerides; however, our understanding
of these reservoirs is in its infancy. This review focuses on recent work identifying circulating oxylipins, primarily esterified
with lipoprotein lipids, and their effects on markers of endothelial dysfunction. These oxyli...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
The omega-3 index: From biomarker to risk marker to risk factorEmail this article to a colleague.
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Abstract Blood levels of omega-3 fatty acids reflect the interplay of metabolism and the intake of omega-3-rich foods (eg, oily fish).
Multiple lines of evidence link reduced tissue and/or blood levels of omega-3 fatty acids, as reflected in the erythrocyte
eicosapentaenoic acid plus docosahexaenoic acid level (ie, the omega-3 index), with increased risk for coronary heart disease,
especially sudden cardiac death. The purpose of this review is to examine the extent to which biomarkers like the omega-3
index qualify as coronary heart disease risk markers and/or risk factors based on new criteria from the Amer...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Nutritional supplements and serum lipids: Does anything work?Email this article to a colleague.
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Abstract Hyperlipidemia is a risk factor for the development of coronary heart disease. Many patients decline prescription lipid-lowering
agents and opt instead for supplements. Before any supplement can be routinely recommended it is crucial to examine the types
of clinical trials that have been performed, the mechanism by which a supplement is felt to alter lipids, the population studied,
potential adverse effects, and the possibility that investigators might be biased. Clinical trial evidence strongly supports
the notion that both red yeast rice and plant stanols and sterols effectively lower low-density ...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Carotenoids and cardiovascular diseaseEmail this article to a colleague.
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Abstract Carotenoids are a class of natural fat-soluble pigments found principally in plants. They have potential antioxidant biological
properties due to their chemical structure and interaction with biological membranes. The most abundant carotenoids in the
diet are β-carotene, lycopene, lutein, β-cryptoxanthin, zeaxanthin, and astaxanthin. Numerous epidemiologic studies have supported
the hypothesis that antioxidants could be used as an inexpensive means of prevention, and possibly treatment, of cardiovascular
diseases, even though findings from interventional trials have been mixed, with some positive ...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Vitamin D and cardiovascular diseaseEmail this article to a colleague.
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Abstract Recent studies indicate that deficient vitamin D status may increase risk of both ischemic and nonischemic cardiovascular
diseases independently of established cardiovascular risk factors. The role of vitamin D in potentially regulating many functions
in the cardiovascular system is just beginning to be understood. Among the potentially relevant mechanisms for cardiovascular
diseases, vitamin D may influence blood pressure through the renin-angiotensin system, parathyroid hormone levels, myocardial
function, inflammation, and vascular calcification. Cardiovascular risk appears especially elevated at...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Cardiovascular disease-related genes and regulation by dietEmail this article to a colleague.
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This article reviews the evidence that specific receptors
exist for fatty acids or their metabolites that are able to regulate gene expression and coordinately affect metabolic or
signaling pathways associated with CVD. Four nuclear receptor subfamilies that respond to dietary and endogenous ligands and
have implications for CVD are emphasized in this article: peroxisome proliferator-activated receptors, retinoid X receptors,
liver X receptors, and the farnesoid X receptor.
Content Type Journal ArticleDOI 10.1007/s11883-009-0067-xAuthors
John P. Vanden Heuvel, Penn State University Department of Veterinary and Bio...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Dietary cholesterol and coronary artery disease: A systematic reviewEmail this article to a colleague.
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This article reviews the
current evidence on the association between dietary cholesterol and the risk of CHD.
Content Type Journal ArticleDOI 10.1007/s11883-009-0063-1Authors
Luc Djoussé, Brigham and Women’s Hospital and Harvard Medical School Division of Aging, Department of Medicine 1620 Tremont Street, 3rd floor Boston MA 02120 USAJ. Michael Gaziano
Journal Current Atherosclerosis ReportsOnline ISSN 1534-6242Print ISSN 1523-3804
Journal Volume Volume 11
Journal Issue Volume 11, Number 6 / November, 2009
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Carbohydrate-restricted diets for obesity and related diseases: An updateEmail this article to a colleague.
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Abstract Basic, clinical, and epidemiologic research on carbohydrate-restricted dietary patterns continues to grow, evaluating the
impact of this way of eating on weight loss, obesity-associated comorbidities, and development of any adverse effects. Randomized,
controlled, dietary weight loss trials conducted in adults in the past 2 years reinforce previous findings that carbohydrate-restricted
diets (CRDs) promote weight loss while increasing serum high-density lipoprotein cholesterol, lowering serum triglycerides,
and improving glucose homeostasis. Studies showing that reduction of dietary carbohydrate lea...
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
Substudies of the Japan EPA lipid intervention study (JELIS)Email this article to a colleague.
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Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11883-009-0071-1Authors
William S. Harris, Cardiovascular Health Research Center and the Sanford School of Medicine at the University of South Dakota South Dakota USA
Journal Current Atherosclerosis ReportsOnline ISSN 1534-6242Print ISSN 1523-3804
Journal Volume Volume 11
Journal Issue Volume 11, Number 6 / November, 2009
Source: Current Atherosclerosis Reports - November 4, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals
JACC: Adding SPECT to calcium scoring can better predict heart riskEmail this article to a colleague.
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Adding coronary artery calcium score testing in patients with a normal SPECT scan could help to identify those at high long-term risk for cardiac events, in whom an earlier focus on aggressive risk factor modification and other medical therapies may be beneficial, according to new findings published in the Nov. 10 issue of the Journal of the American College of Cardiology.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
JACC: SPECT+calcium scoring may be superior predictor of heart riskEmail this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Adding coronary artery calcium score testing with CT in patients with a normal SPECT scan could help to identify those at high long-term risk for cardiac events, in whom an earlier focus on aggressive risk factor modification and other medical therapies may be beneficial, according to new findings published in the Nov. 10 issue of the Journal of the American College of Cardiology.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
