Cardiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 21.
No CV risk reduction with B vitamins posttransplant
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In keeping with all the other evidence showing no effects of homocysteine-lowering with B vitamins, the FAVORIT study now confirms that this lack of benefit is also seen in renal-transplant recipients.
Source: theHeart.org - November 4, 2009 Category: Cardiology Source Type: info
FDA, Cordis recall sheath introducer due to stretching, fractures
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The FDA and Cordis have notified healthcare professionals of a U.S. recall of all lots of the Crossover Sheath Introducer, a long-coil reinforced, kink-resistant catheter sheath intended for use in arterial and venous procedures requiring the percutaneous introduction of therapeutic or diagnostic intravascular devices or fluids.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
EU greenlights Novartis’ 3-in-1 hypertension pill
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The European Commission has granted Novartis marketing authorization for Exforge HCT, a new 3-in-1 treatment for people with high blood pressure.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Abbott completes $410M purchase of mitral valve repair developer
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Abbott has completed its acquisition of Evalve, a developer of devices for minimally invasive repair of mitral valves.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Edwards, DexCom earn CE Mark for glucose monitoring system
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Edwards Lifesciences, a developer of heart valves and hemodynamic monitoring systems, and DexCom, a continuous glucose monitoring systems developer, have received a CE Mark for an automatic glucose monitoring system.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
NEJM: Off-pump CABG leads to poorer outcomes, graft patency at one year
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Patients in the off-pump group had worse composite outcomes and poorer graft patency compared with patients undergoing coronary artery bypass grafting (CABG) with the use of a cardiopulmonary bypass machine at one year of follow up, according to a study in Thursday’s issue of the New England Journal of Medicine.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
The role of echocardiography in guiding management in dilated cardiomyopathy
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This article therefore explores the pivotal role of echocardiography in the evaluation and management of patients with DCM.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Thomas, D. E., Wheeler, R., Yousef, Z. R., Masani, N. D. Tags: BRITISH SOCIETY OF ECHOCARDIOGRAPHY AUTUMN SUPPLEMENT 2009 Source Type: journals
Restrictive cardiomyopathies
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constitute a heterogenous group of heart muscle conditions that all have, in common, the symptoms of heart failure. Diastolic dysfunction with preserved systolic function is often the only echocardiographic abnormality that may be noted, although systolic dysfunction may also be an integral part of some specific pathologies, particularly in the most advanced cases such as amyloid infiltration of the heart. By far, the majority of restrictive cardiomyopathies are secondary to a systemic disorder such as amyloidosis, sarcoidosis, scleroderma, haemochromatosis, eosinophilic heart disease, or as a result of radiation treatmen...
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Nihoyannopoulos, P., Dawson, D. Tags: BRITISH SOCIETY OF ECHOCARDIOGRAPHY AUTUMN SUPPLEMENT 2009 Source Type: journals
Preface * BSE Autumn Supplement 2009
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Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Steeds, R. Tags: BRITISH SOCIETY OF ECHOCARDIOGRAPHY AUTUMN SUPPLEMENT 2009 Source Type: journals
Anatomy and myoarchitecture of the left ventricular wall in normal and in disease
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The normal left ventricle comprises an inlet, apical trabecular, and an outlet portion although these portions do not have discrete anatomical borders. The ventricular wall is thickest near the cardiac base and thins to 1–2 mm at the apex. Characteristically, the muscle bundles at the apical portion are thin, but there are also thicker bundles and very fine strands that may be mistaken on imaging as pathologies. Transmurally through the ventricular wall, the myoarchitecture has a typical arrangement of myocardial strands that change orientation from being oblique in the subepicardium to circumferential in the middle ...
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Ho, S. Y. Tags: BRITISH SOCIETY OF ECHOCARDIOGRAPHY AUTUMN SUPPLEMENT 2009 Source Type: journals
Echocardiography in hypertrophic cardiomyopathy diagnosis, prognosis, and role in management
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Hypertrophic cardiomyopathy (HCM) is diagnosed on the basis of left ventricular (LV) hypertrophy for which there is insufficient explanation (e.g. mild hypertension or mild aortic stenosis with marked hypertrophy). Echocardiography is an invaluable tool in the diagnosis and follow-up of patients with HCM. Echocardiographic assessment requires a comprehensive assessment in several imaging planes with careful attention to correct beam alignment in order to minimize errors in the measurement of LV wall thickness and appropriate identification of hypertrophy with an unusual distribution.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Williams, L.K., Frenneaux, M.P., Steeds, R.P. Tags: BRITISH SOCIETY OF ECHOCARDIOGRAPHY AUTUMN SUPPLEMENT 2009 Source Type: journals
European Association of Echocardiography recommendations for training, competence, and quality improvement in echocardiography
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The main mission statement of the European Association of Echocardiography (EAE) is ‘to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular ultrasound in Europe’. As competence and quality control issues are increasingly recognized by patients, physicians, and payers, the EAE has established recommendations for training, competence, and quality improvement in echocardiography. The purpose of this document is to provide the requirements for training and competence in echocardiography, to outline the principles of quality measurement, and to recommend a set o...
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Popescu, B. A., Andrade, M. J., Badano, L. P., Fox, K. F., Flachskampf, F. A., Lancellotti, P., Varga, A., Sicari, R., Evangelista, A., Nihoyannopoulos, P., Zamorano, J. L., on behalf of the European Association of Echocardiography, Document Reviewers, De Tags: EAE RECOMMENDATIONS Source Type: journals
Changes to EAE laboratory accreditation
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Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Ray, S., Fox, K. Tags: LETTER TO THE EDITOR Source Type: journals
Effect of intraventricular dyssynchrony on diastolic function and exercise tolerance in patients with heart failure
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Conclusion
Intraventricular dyssynchrony correlates with higher LV filling pressure and lower ejection fraction and it is an independent predictor of poor aerobic capacity; it may be helpful for functional evaluation of CHF patients.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Ciampi, Q., Petruzziello, B., Porta, M. D., Caputo, S., Manganiello, V., Astarita, C., Villari, B. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Influence of afterload on left ventricular radial and longitudinal systolic functions: a two-dimensional strain imaging study
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Conclusion
2D-S shows a different response in longitudinal and radial functions to increased afterload. Longitudinal function is early impaired, whereas radial function remains preserved. This finding justifies the combined assessment of both radial and longitudinal regional myocardial functions to characterize myocardial dysfunction and might help to better identify the transition to heart failure in pressure-overload cardiomyopathy.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Donal, E., Bergerot, C., Thibault, H., Ernande, L., Loufoua, J., Augeul, L., Ovize, M., Derumeaux, G. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Rapid method for intraoperative assessment of aortic coarctation using three-dimensional echocardiography
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Conclusion
Intraoperative 3D echography is a feasible non-invasive imaging modality for intraoperative assessment of CoA and its repair, which provides useful additional information.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Scohy, T. V., du Plessis, F., McGhie, J., de Jong, P. L., Bogers, A. J.J.C. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Subclinical left ventricular dysfunction in asymptomatic diabetic patients assessed by two-dimensional speckle tracking echocardiography: correlation with diabetic duration
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Conclusion
In addition to diastolic dysfunction, subclinical LV longitudinal dysfunction is preferentially and frequently observed in asymptomatic diabetes patients with normal LVEF. The decrease in LS correlated with duration of diabetes. 2DSTE has the potential for detecting subclinical LV systolic dysfunction and might provide useful information of the risk stratification in an asymptomatic diabetic population.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Nakai, H., Takeuchi, M., Nishikage, T., Lang, R. M., Otsuji, Y. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Improved prediction of outcome by contrast echocardiography determined left ventricular remodelling parameters compared to unenhanced echocardiography in patients following acute myocardial infarction
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Conclusion
Contrast echocardiography provided improved prediction of outcome compared with unenhanced echocardiography following AMI.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Dwivedi, G., Janardhanan, R., Hayat, S. A., Lim, T. K., Senior, R. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Gender differences in systolic tissue velocity: role of left ventricular length
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Conclusion
In controls, systolic tissue velocities are significantly higher in males compared with females, which may be explained by the increased chamber size of men.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Holland, D. J., Sharman, J. E., Leano, R. L., Marwick, T. H. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Biventricular and atrial diastolic function assessment using conventional echocardiography and tissue-Doppler imaging in adults with Marfan syndrome
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Conclusion
This study demonstrated significant biventricular diastolic and biatrial systolic and diastolic dysfunction in MFS patients. Our findings suggest that MFS affects diastolic function independently. Diastolic abnormalities could be attributed to fibrillin-1 deficiency and dysregulation of transforming growth factor-β activity in the cardiac extracellular matrix.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Kiotsekoglou, A., Moggridge, J. C., Bijnens, B. H., Kapetanakis, V., Alpendurada, F., Mullen, M. J., Saha, S., Nassiri, D. K., Camm, J., Sutherland, G. R., Child, A. H. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Analysis of regional wall motion during contrast-enhanced dobutamine stress echocardiography: effect of contrast imaging settings
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Conclusion
Myocardial contrast perfusion echocardiography provides equal endocardial border delineation compared with LVO modality. Although the inter-observer agreement is slightly higher with LVO compared with MCE, it is not significantly different with MCE at peak stress. Despite the similar improvement in endocardial border delineation, LVO settings allow the detection of more WMA than MCE at peak stress, leading to a significantly higher accuracy for the detection of ischaemia in patients suspected of coronary artery disease when only wall motion is taken into account.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Cosyns, B., Van Camp, G., Droogmans, S., Weytjens, C., Schoors, D., Lancellotti, P. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Three-dimensional echocardiographic assessments of exercise-induced changes in left ventricular shape and dyssynchrony in patients with dynamic functional mitral regurgitation
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Conclusion
Dynamic MR during exercise is related to the 3D changes in LV shape and in LV synchronicity.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Izumo, M., Lancellotti, P., Suzuki, K., Kou, S., Shimozato, T., Hayashi, A., Akashi, Y. J., Osada, N., Omiya, K., Nobuoka, S., Ohtaki, E., Miyake, F. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Late gadolinium enhancement-cardiovascular magnetic resonance identifies coronary artery disease as the aetiology of left ventricular dysfunction in acute new-onset congestive heart failure
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Conclusion
In patients with new-onset HF and LVSD for whom there are no clinical and exploratory data suggestive of ischaemic heart disease, CMR with LGE is an excellent means of ruling out significant CAD and is a valid alternative to angiography.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Valle-Munoz, A., Estornell-Erill, J., Soriano-Navarro, C. J., Nadal-Barange, M., Martinez-Alzamora, N., Pomar-Domingo, F., Corbi-Pascual, M., Paya-Serrano, R., Ridocci-Soriano, F. Tags: CLINICAL/ORIGINAL PAPERS Source Type: journals
Echocardiographic assessment of a cardiac lymphoma: beyond two-dimensional imaging
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We present a case of secondary cardiac lymphoma in an HIV patient presenting with heart failure. Transthoracic echocardiography showed increased left ventricular (LV) wall thickness and an extensive mass in the right cavities with involvement of the tricuspid annulus (Figure 1). Doppler tissue imaging (DTI) showed reduced systolic and diastolic velocities at mitral and tricuspid annulus, compatible with systolic and diastolic myocardial dysfunction, likely owing to infiltration. After 2 weeks of chemotherapy, repeated exam showed significant reduction of the tumour mass and of the LV wall thickness, as well as normalized s...
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Gaspar, A., Salome, N., Nabais, S., Brandao, A., Simoes, A., Portela, C., Salgado, A., Pereira, A., Correia, A. Tags: CASE REPORTS Source Type: journals
Usefulness of 3D transoesophageal echocardiography for guiding wires and closure devices in mitral perivalvular leaks
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Sixty-three-year-old male patient. Previous history of rheumatic valvular disease. He underwent multiple mitral and aortic valve replacements. Nowadays, he presents a periprosthetic mitral leak. He underwent a leak closure by using a percutaneous approach. During the procedure, the superiority of 3D TEE over 2D TEE was confirmed for wires and device positioning, excluding interference with the prosthesis discs and evaluating the residual periprosthetic regurgitation.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Becerra, J. M., Almeria, C., de Isla, L. P., Zamorano, J. Tags: CASE REPORTS Source Type: journals
Three-dimensional transoesophageal echocardiography in a patient undergoing percutaneous mitral valve repair using the edge-to-edge clip technique
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We report a case of percutaneous mitral valve repair, using the Mitraclip device, in which we show that application of real-time three-dimensional transoesophageal echocardiography (3D-TEE) is extremely helpful for the guidance of this procedure. Because of its excellent visualization capacities, 3D-TEE simplifies the transseptal puncture, the positioning of the clip above the mitral valve orifice, the grasping of the mitral valve leaflets, and the evaluation of the final result. Therefore, we conclude that 3D-TEE has the potential to increase the safety and efficacy of this new technique to treat mitral regurgitation in p...
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Swaans, M.J., Van den Branden, B.J.L., Van der Heyden, J.A.S., Post, M.C., Rensing, B.J.W.M., Eefting, F.D., Plokker, H.W.M., Jaarsma, W. Tags: CASE REPORTS Source Type: journals
Tissue Doppler imaging and contrast-enhanced cardiac magnetic resonance in primary cardiac amyloidosis
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A 64-year-old female presented with biventricular heart failure. Echocardiography revealed features suggestive of amyloidosis, including segmental impairment of longitudinal strain (rate) in the septal and anterior segments, which matched delayed gadolinium-enhanced cardiac magnetic resonance. Guided endomyocardial biopsy confirmed the presence of perivascular amyloid deposits. Tissue Doppler and gadolinium-enhanced magnetic resonance may be helpful in delineating cardiac amyloidosis.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Smedema, J.-P., James, R. Tags: CASE REPORTS Source Type: journals
Transthoracic echocardiography after heart surgery: could pleural view be of some help?
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The pericardial effusion localized on the upper portion of the right atrium is a classical complication of the post-operative heart surgery setting. This issue is most likely not visualized by transthoracic echocardiography and needs the transoesophageal approach. The present case reports a situation where an associated bilateral pleural effusion permitted a new view of the heart which has been helpful to confirm the diagnosis of tamponade and to re-transfer the patient to the operative room.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Schutz, N., Bendjelid, K. Tags: CASE REPORTS Source Type: journals
Massive intraventricular thrombi in a previously healthy 43-year-old male
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We report a case of 43-year-old previously healthy male admitted to our hospital with symptoms of heart failure. Two-dimensional echocardiography demonstrated a previously undiagnosed dilated cardiomyopathy and massive left intraventricular thrombi. Because patient did not give consent for surgical thrombectomy, thrombolytic treatment with streptokinase was introduced. In the further course of hospitalization, ischaemic stroke was diagnosed despite the resolution of intracardiac thrombi observed on serial control echocardiography.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Szymczyk, E., Lipiec, P., Kasprzak, J. Tags: CASE REPORTS Source Type: journals
Huge cardiac cyst hydatid causing cardiac symptoms and electrocardiographic changes
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Here we present a huge cardiac cyst hydatid case with wonderful echocardiographic and computed tomographic images, causing cardiac symptoms and electrocardiographic changes.
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Yuksel, S., Gulel, O., Elmali, M., Kale, A., Sahin, M. Tags: CASE REPORTS Source Type: journals
Nutcracker syndrome
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Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Natale, F., Granato, C., Aronne, L., Di Marco, G. M., Lo Priore, E., Mocerino, R., Cirillo, C., Calabro, P., Golino, P., Russo, M. G., Calabro, R. Tags: VASCULAR ECHO VIGNETTE Source Type: journals
Making sense of echocardiography: a hands-on guide. By Andrew Houghton
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Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Soliman, O. I. Tags: BOOK REVIEWS Source Type: journals
Critical Decisions in Emergency and Acute Care Electrocardiography. By William J. Brady and Jonathon D. Truwit
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Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Van Belle, Y. Tags: BOOK REVIEWS Source Type: journals
Boston Sci earns CE Mark for Promus Element DES
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Boston Scientific has received CE Mark for the Promus Element everolimus-eluting coronary stent system, its third-generation drug-eluting stent (DES) technology.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Another in-hospital CV risk marker: 24-hour shifts with overnight on-call duty
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Long work shifts with nighttime on-call duty, with the inevitable interruptions of sleep, are associated with ECG, blood-pressure, and biochemical changes associated with increased cardiovascular risk, suggests a randomized crossover study that hints at a sustained effect on the risk markers if the 24-hour shifts happen too frequently.
Source: theHeart.org - November 4, 2009 Category: Cardiology Source Type: info
Anemia treatment fails to improve outcomes in Type 2 diabetics with CKD
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Results from the TREAT study show that darbepoetin alfa treatment for anemia does not improve cardiovascular or renal outcomes or related mortality of patients with Type 2 diabetes, chronic kidney disease, and moderate anemia.
Source: MedWire News - Cardiology - November 4, 2009 Category: Cardiology Source Type: news
CHEST: Statins may worsen symptoms in some heart failure patients
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A study presented Wednesday at CHEST 2009 in San Diego, the 75th annual scientific assembly of the American College of Chest Physicians (ACCP), found that statins have beneficial effects on patients with systolic heart failure (HF), but those with diastolic HF experienced the opposite effect, including increased dyspnea, fatigue and decreased exercise tolerance.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Proper data reporting tied to 2010 HOPPS payment hikes
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In the Centers for Medicare & Medicaid Services’ (CMS) 2010 Hospital Outpatient Prospective Payment System (HOPPS) final rule, hospitals will receive a 2.1 percent inflation update for services furnished to Medicare beneficiaries in outpatient settings. However, the agency will reduce the update by 2 percentage points for hospitals that did not participate in quality data reporting for outpatient services or did not report the quality data successfully, resulting in a 0.1 percent update for those facilities.
Source: Cardiovascular Business News - November 4, 2009 Category: Cardiology Tags: Latest News Source Type: news
Mayo Clinic Proceedings: New Methods Found Useful For Diagnosing Myocarditis
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Myocarditis is an important, and often unrecognized cause of dilated cardiomyopathy (DCM). Several new diagnostic methods, such as cardiac magnetic resonance imaging (MRI), are useful for diagnosing myocarditis, according to a study published in the November 2009 issue of Mayo Clinic Proceedings. "The use of MRI is particularly significant in the diagnosis of patients with myocarditis because it is a standard, noninvasive method," says Leslie Cooper Jr., M.D.
Source: Cardiovascular / Cardiology News From Medical News Today - November 4, 2009 Category: Cardiology Tags: Heart Disease Source Type: news
Journal Scan: Efficacy and Economic Assessment of Conventional Ventilatory Support Versus Extracorporeal Membrane Oxygenation for Severe Adult Respiratory Failure (CESAR): A Multicentre Randomised Controlled Trial (Lancet 2009;374:1351-1363.)
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Of the 766 patients screened, the investigators randomized 180 adults to receive continued conventional management (n = 90) or referral to consideration for treatment by ECMO (n = 90). Inclusion criteria were ages 18-65 years and had severe (Murray score >3.0 or pH 30 cm H2O of peak inspiratory pres. . .
Source: Cardiosource - November 4, 2009 Category: Cardiology Source Type: organizations
Statins May Worsen Fatigue in Heart Failure Patients
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Title: Statins May Worsen Fatigue in Heart Failure PatientsCategory: Health NewsCreated: 11/3/2009 2:10:00 PMLast Editorial Review: 11/4/2009
Source: MedicineNet Cholesterol General - November 4, 2009 Category: Cardiology Source Type: consumer
How Safe Are Popular Reflux Drugs?
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Title: How Safe Are Popular Reflux Drugs?Category: Health NewsCreated: 11/4/2009 8:10:00 AMLast Editorial Review: 11/4/2009
Source: MedicineNet Cholesterol General - November 4, 2009 Category: Cardiology Source Type: consumer
Statins May Worsen Fatigue in Heart Failure Patients
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Title: Statins May Worsen Fatigue in Heart Failure PatientsCategory: Health NewsCreated: 11/3/2009 2:10:00 PMLast Editorial Review: 11/4/2009
Source: MedicineNet Heart General - November 4, 2009 Category: Cardiology Source Type: consumer
How Safe Are Popular Reflux Drugs?
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Title: How Safe Are Popular Reflux Drugs?Category: Health NewsCreated: 11/4/2009 8:10:00 AMLast Editorial Review: 11/4/2009
Source: MedicineNet Heart General - November 4, 2009 Category: Cardiology Source Type: consumer
H1N1 Swine Flu Deadly in All Age Groups
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Title: H1N1 Swine Flu Deadly in All Age GroupsCategory: Health NewsCreated: 11/4/2009 10:29:00 AMLast Editorial Review: 11/4/2009 10:29:07 AM
Source: MedicineNet High Blood Pressure General - November 4, 2009 Category: Cardiology Source Type: consumer
CVN: Heart Minute
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Early ICD Use After MI
Source: Cardiosource - November 4, 2009 Category: Cardiology Source Type: organizations
Clopidogrel 75mg tablets to move to Part VIII Category A in December
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Source: PSNC
Area: News
According to the PSNC, the Department of Health has confirmed that clopidogrel 75mg tablets will be moved to Category A of the Drug Tariff with effect 1st December 2009.
Therefore, from 1st December, the Part VIII reference price of clopidogrel will be the weighted average of the prices for generic clopidogrel listed by the following suppliers and manufacturers: AAH, Alliance Healthcare, Teva and Activas. Where a prescription is received for clopidogrel, pharmacies can fulfill the prescription with clopidogrel besilate or clopidogrel hydrochloride, but regardless of which product they su...
Source: NeLM - Cardiovascular Medicine - November 4, 2009 Category: Cardiology Source Type: organizations
MHRA publishes public assessment report of adverse effects associated with statins
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Source: MHRA
Area: News
The MHRA has published a Public Assessment Report summarising adverse drug reaction reports and published literature on statins, which concluded that sleep disturbances, memory loss, sexual dysfunction, depression and interstitial lung disease (leading to breathing problems) may be associated with statin use.
The product information for all statins will be updated with warnings on all of these side effects.
Source: NeLM - Cardiovascular Medicine - November 4, 2009 Category: Cardiology Source Type: organizations
Up to a third of stent patients stop thienopyridine anti-platelet therapy within six months
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Source: No information given
Area: News
Analysis of Canadian healthcare data found that up to a third of patients who had implantation of a cardiac stent (bare-metal, BMS, or drug-eluting, DES) were no longer taking recommended thienopyridine (clopidogrel, ticlopidine) therapy by six months after the procedure.
It is accepted that patients who have a stent implanted should have long-term anti-platelet therapy, including at least twelve months of a thienopyridine (normally clopidogrel). There is limited information on how many patients actually continue for the full treatment period, and this study was intended ...
Source: NeLM - Cardiovascular Medicine - November 4, 2009 Category: Cardiology Source Type: organizations
Risk factors for non-adherence to heart failure medication
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Source: Am Heart J
Area: News
An epidemiological study suggests that non-adherence to therapy is a significant cause of re-admission for heart failure, however treatment of these patients is generally straightforward.
Heart failure (HF) is a significant cause of hospital admission, and many patients will be re-admitted - a factor that predicts poorer long term outcomes. It is not clear what proportion of re-admissions are due to non-adherence to the sometimes complex drug and dietary regimens used in treatment of HF, and the authors of this study intended to clarify these in a large adult patient population. Th...
Source: NeLM - Cardiovascular Medicine - November 4, 2009 Category: Cardiology Source Type: organizations
