Cardiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 27.
Adult Congenital Patients in the Hospital—Where the Rubber Meets the Road
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Source: Congenital Heart Disease - November 1, 2009 Category: Cardiology Authors: Douglas Moodie Tags: EDITORIAL Source Type: journals
Migraine Tied to CV ComplicationsEmail this article to a colleague.
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PHILADELPHIA — Migraine with or without aura was associated with a significant increase in the risk of cardiovascular disease, including stroke and heart attack, in a population-based study that included more than 6,000 U.S. adults with migraine.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MICHELE G. SULLIVAN Tags: News Source Type: news
Stenting Effective For Left Main Disease in ACS: Common strategy for sickest patients.Email this article to a colleague.
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BARCELONA — Coronary artery stenting is used increasingly to treat the sickest patients with acute coronary syndrome, and the 180-day outcomes have been reasonable, with 80% of these patients surviving for 6 months beyond their initial hospitalization, based on data from almost 1,800 registry patients.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MITCHEL L. ZOLER Tags: News Source Type: news
Research Into Cardiac Stem Cells at CrossroadsEmail this article to a colleague.
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BETHESDA, MD. — It may be time for a retrenching in basic science when it comes to the use of stem cells to treat heart disease. That was the consensus expressed by prominent researchers at a National Heart, Lung, and Blood Institute–sponsored symposium last month.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: ALICIA AULT Tags: News Source Type: news
Mission: LifelineEmail this article to a colleague.
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Dr. Goldstein, medical editor of Cardiology News, is professor of medicine at Wayne State University and division head emeritus of cardiovascular medicine at Henry Ford Hospital, both in Detroit.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: SIDNEY GOLDSTEIN Tags: Heart of the Matter Source Type: news
Vital Signs: Top 10 Corporations by Dispensed Prescriptions, 2008Email this article to a colleague.
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Source: Cardiology News - November 1, 2009 Category: Cardiology Tags: News Source Type: news
Bromocriptine Reversed PPCM in Small TrialEmail this article to a colleague.
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BARCELONA — Adding bromocriptine to standard heart failure therapy in women with peripartum cardiomyopathy improved survival and produced major gains in left ventricular systolic and diastolic function in the first-ever randomized trial of this novel therapy.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: BRUCE JANCIN Tags: News Source Type: news
Meta-Analysis: Targeted PAH Therapies Cut Mortality 43%Email this article to a colleague.
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BARCELONA — Targeted therapies for pulmonary arterial hypertension collectively reduced all-cause mortality by 43% compared with placebo, in a meta-analysis of the randomized, placebo-controlled, clinical trials conducted during the past 18 years.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: BRUCE JANCIN Tags: News Source Type: news
Heart Failure Patients Need Better Flu ProtectionEmail this article to a colleague.
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BOSTON — Patients with heart failure do not maintain protective levels of antibody titres following influenza vaccination, leaving this already at-risk population even more vulnerable to influenza-related complications, according to a study presented at the annual scientific meeting of the Heart Failure Society of America.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: DIANA MAHONEY Tags: News Source Type: news
Fractional Flow Reserve as PCI Guide Costs LessEmail this article to a colleague.
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BARCELONA — Using fractional flow reserve to guide coronary stenting produced a sizeable reduction in treatment costs during the year afterward in a randomized study with about 1,000 patients.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MITCHEL L. ZOLER Tags: Interventional Cardiology Source Type: news
Doubling Clopidogrel Aids Stented ACS Patients: In CURRENT-OASIS7, 600-mg loading dose cut ischemic and thrombotic events, increased bleeding.Email this article to a colleague.
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BARCELONA — Doubling the clopidogrel dosage for a week following coronary artery stenting led to significantly fewer thrombotic events and a small increase in bleeds in a major study of more than 25,000 acute coronary syndrome patients.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MITCHEL L. ZOLER Tags: Interventional Cardiology Source Type: news
Novel Drug Cuts Acute MIs in Selected PatientsEmail this article to a colleague.
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BARCELONA — Ivabradine reduced hospitalizations for acute MI by 73% in patients with stable coronary artery disease and left ventricular systolic dysfunction who had limiting angina and a baseline resting heart rate of 70 bpm or more, according to a new analysis from the BEAUTIFUL trial.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: BRUCE JANCIN Tags: Cad & Atherosclerosis Source Type: news
Allopurinol for Angina Improves Exercise TimeEmail this article to a colleague.
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BARCELONA — Allopurinol treatment for 6 weeks significantly improved symptoms of chronic, stable angina in a randomized, placebo-controlled, crossover study of 60 patients. Allopurinol administered at labeled dosages produced three significant improvements during an exercise treadmill test, which were the study's primary end points: increased total exercise time, increased time to ST-segment depression, and increased time to angina, Dr. Awsan Noman said at the annual congress of the European Society of Cardiology.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MITCHEL L. ZOLER Tags: Cad & Atherosclerosis Source Type: news
Psoriasis Not Linked to CV HospitalizationsEmail this article to a colleague.
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BUDAPEST — The last word on the relationship between psoriasis and cardiovascular disease may not be in, according to the results of a new study. Contrary to earlier studies, psoriasis was found to not be an independent risk factor for hospitalization for ischemic heart disease in a large Dutch study, Dr. Marlies Wakkee reported at the annual congress of the European Society for Dermatological Research.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: BRUCE JANCIN Tags: Epidemiology & Prevention Source Type: news
MI, Stroke Risk Soars With Lupus AnticoagulantEmail this article to a colleague.
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The presence of lupus anticoagulant, an antiphospholipid antibody, increased the risk of stroke by 40-fold and of heart attack by 5-fold in a Dutch study that compared young women who had survived these conditions with a healthy control group.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: JANE SALODOF MacNEIL Tags: Epidemiology & Prevention Source Type: news
Diabetes Raises A-Fib Risk, but Just in WomenEmail this article to a colleague.
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VIENNA — Diabetes was a significant risk factor for atrial fibrillation among women but not men in an analysis of electronic medical records from a large HMO database. The study also found that both the prevalence and the incidence of atrial fibrillation (AF) were more than 40% higher among patients with diabetes than in those without. After the researchers accounted for other risk factors, diabetes increased the risk for AF by 16%, Gregory A. Nichols, Ph.D., said in an interview prior to his presentation of the findings at the annual meeting of the European Association for the Study of Diabetes.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MIRIAM E. TUCKER Tags: Arrhythmias & Electrophysiology Source Type: news
Statin Is Mildly Protective Against AF in Heart FailureEmail this article to a colleague.
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BARCELONA — Rosuvastatin exerted a “modest” preventive effect against the occurrence of atrial fibrillation in patients with chronic heart failure, according to a secondary analysis of the Italian GISSI-Heart Failure study.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: BRUCE JANCIN Tags: Arrhythmias & Electrophysiology Source Type: news
Quick ICD Post MI Raises Nonsudden Cardiac DeathEmail this article to a colleague.
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Placement of an implantable cardioverter defibrillator immediately following a myocardial infarction didn't reduce mortality in patients at high risk for arrhythmia in a randomized trial.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MARY ANN MOON Tags: Arrhythmias & Electrophysiology Source Type: news
Erythropoietin May Improve HF-Related AnemiaEmail this article to a colleague.
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BARCELONA — Erythropoietin therapy in patients with anemia of heart failure resulted in improved exercise capacity, reduced heart failure symptoms, and decreased hospitalizations, and showed strong trends for reduced rates of MI and all-cause mortality in a meta-analysis of 11 small randomized clinical trials.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: BRUCE JANCIN Tags: Heart Failure Source Type: news
Process-of-Care Intervention Improves Outpatient HF CareEmail this article to a colleague.
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BOSTON — Pperformance improvement intervention for outpatient care of heart failure patients increases the use of evidence-based, guideline-recommended processes and therapies, Dr. Clyde W. Yancy said at the annual meeting of the Heart Failure Society of America.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: DIANA MAHONEY Tags: Heart Failure Source Type: news
Trials Need to Include More Hispanics to Unravel ParadoxEmail this article to a colleague.
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CHICAGO — Despite the underrepresentation of Hispanics in heart failure trials, evidence has emerged suggesting that they have unique risk factors and outcomes that must be taken into clinical consideration.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: PATRICE WENDLING Tags: Heart Failure Source Type: news
ICDs Don't Save Women With Heart FailureEmail this article to a colleague.
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Implantable cardioverter defibrillators do not reduce all-cause mortality in women who have advanced heart failure, unlike in men, according to a meta-analysis. “ICDs are being implanted in hundreds of thousands of women without substantial evidence of benefit, apparently based on the assumption that, to paraphrase the old saying, ‘What's good for the gander is good for the goose,’” Dr. Rita F. Redberg said in an accompanying editorial (Arch. Intern. Med. 2009;169:1460–1).
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MARY ANN MOON Tags: Heart Failure Source Type: news
Initiative Speeds Reperfusion Treatment TimeEmail this article to a colleague.
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BOSTON — A statewide program to get patients with severe heart attacks to hospitals faster significantly reduced disparities in reperfusion treatment times for women and elderly patients, based on a study of more than 900 patients in North Carolina.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: HEIDI SPLETE Tags: Acute Coronary Syndromes Source Type: news
Sulfonylureas Tied to Mortality in MI SurvivorsEmail this article to a colleague.
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BARCELONA — Four widely prescribed oral sulfonylurea drugs are associated with significantly increased risk of all-cause mortality compared with metformin in type 2 diabetic patients having a history of MI, according to a comprehensive Danish national cohort study.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: BRUCE JANCIN Tags: Acute Coronary Syndromes Source Type: news
Heart Defect Screening Indicated in Turner'sEmail this article to a colleague.
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NEW YORK — Partial anomalous pulmonary venous return was detected by cardiac magnetic resonance imaging in 7 of 39 adolescent and young adult women with Turner's syndrome whose charts were retrospectively evaluated.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MIRIAM E. TUCKER Tags: Congenital Heart Diseases Source Type: news
Policy & PracticeEmail this article to a colleague.
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Can't get enough Policy & Practice? Check out our new podcast each Monday. egmnblog.wordpress.com The American Medical Association's Current Procedural Terminology (CPT) panel has approved four new Category 1 codes for cardiac computed tomography, which replace current Category III codes. The new codes were the result of a joint effort by professional societies including the American College of Radiology and the Society of Cardiovascular Computed Tomography. The codes will go into effect Jan. 1, 2010. They are 75571 (calcium scoring), 75572 (pulmonary veins), 75573 (congenital heart disease), and 75574 (coronary CT angiog...
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: Alicia Ault Tags: Practice Trends Source Type: news
Feds Issue Rules for Use of Genetic Information by InsurersEmail this article to a colleague.
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The federal government has issued new rules spelling out how it intends to police the use of genetic information by health plans. The regulations bar health insurers from increasing premiums or denying enrollment based on genetic information. The regulations implement certain provisions in the Genetic Information Nondiscrimination Act (GINA), which was signed into law by President Bush in May 2008.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: MARY ELLEN SCHNEIDER Tags: Practice Trends Source Type: news
Data Watch: Medicare, Medicaid Stays Account for 60% of Hospital CostsEmail this article to a colleague.
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Source: Cardiology News - November 1, 2009 Category: Cardiology Tags: Practice Trends Source Type: news
Smaller, Younger Physician Workforce PredictedEmail this article to a colleague.
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More young physicians are entering the workforce than previously thought while fewer older physicians are remaining active, making the physician workforce younger on average, both now and in the future, a recent study of census data showed.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: JANE ANDERSON Tags: Practice Trends Source Type: news
One-Fifth of Presenters Mum On DisclosuresEmail this article to a colleague.
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Despite explicit requirements, a number of speakers at medical meetings do not disclose financial conflicts of interest, a study has found. “Currently, disclosures by physicians are largely self-reported, but there is reason to suspect that this may change in the near future” pending legislation, wrote Dr. Kanu Okike of Brigham and Women's Hospital and Massachusetts General Hospital Boston, and colleagues.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: Joyce Frieden Tags: Practice Trends Source Type: news
On the BeatEmail this article to a colleague.
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Dr. Helmut Drexler, an expert in chronic heart failure and clinical stem cell research, died suddenly on Sept. 13 of cardiac arrest. He was 58. Dr. Drexler, who was director of the department of cardiology and angiology at Hannover (Germany) Medical School (MHH), had collapsed while riding his bicycle.
Source: Cardiology News - November 1, 2009 Category: Cardiology Authors: Jane Locastro Source Type: news
Renal Vascular Disease: A Vexing Challenge for the ClinicianEmail this article to a colleague.
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Few clinical problems raise more controversy and debate among clinicians than the identification and treatment of renal artery stenosis and related syndromes, namely, renovascular hypertension and ischemic nephropathy. This field has rapidly evolved since Goldblatt's seminal findings in the 1930s that hypertension may be induced by partial occlusion of the renal arteries in animal models. On the clinical side, and short of efficacious antihypertensive medications at that time, these findings served as experimental evidence that optimal treatment should rely on surgical revascularization, aimed at improving blood pressure c...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Vincent J. Canzanello, Vesna D. Garovic Tags: Symposium on Renovascular Disease Source Type: journals
Epidemiology and Natural History of Atherosclerotic Renovascular DiseaseEmail this article to a colleague.
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Abstract: Atheromatous renovascular disease (ARVD) is increasingly suspected and diagnosed, and it commonly presents to several different clinical specialties. In this review, the epidemiology, risk factors, comorbid disease associations, natural history, and prognosis of ARVD is described. Atheromatous renovascular disease is strongly associated with macrovascular pathology in other important vascular beds, especially the coronary, aortoiliac and iliofemoral circulations, and also with structural and functional heart disease. These clinicopathologic relationships contribute to the high morbidity and mortality associated w...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Constantina Chrysochou, Philip A. Kalra Tags: Symposium on Renovascular Disease Source Type: journals
Mechanisms of Tissue Injury in Renal Artery Stenosis: Ischemia and BeyondEmail this article to a colleague.
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Abstract: Renal injury distal to an atherosclerotic renovascular obstruction reflects multiple intrinsic factors producing parenchymal tissue injury. Atherosclerotic disease pathways superimposed on renal arterial obstruction may aggravate damage to the kidney and other target organs, and some of the factors activated by renal artery stenosis may in turn accelerate the progression of atherosclerosis. This cross-talk is mediated through amplified activation of renin-angiotensin system, oxidative stress, inflammation, and fibrosis—pathways notoriously involved in renal disease progression. Oxidation of lipids also accelera...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Lilach O. Lerman, Stephen C. Textor, Joseph P. Grande Tags: Symposium on Renovascular Disease Source Type: journals
The Role of the Renin-Angiotensin-Aldosterone System in Renal Artery Stenosis, Renovascular Hypertension, and Ischemic Nephropathy: Diagnostic ImplicationsEmail this article to a colleague.
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Abstract: The renin-angiotensin-aldosterone system (RAAS) has an impressive pathophysiology and numerous systemic correlations, as it is a major regulatory system of vascular and renal function. RAAS represents an important player in the pathogenesis of renal artery stenosis (RAS) and ischemic nephropathy. The activation of the RAAS and sympathetic overactivity are highly responsible for the cardiovascular and renal morbidity in RAS patients. The evaluation of the RAAS activity remains an unsolved issue in the clinical assessment of RAS/ischemic nephropathy with important therapeutic consequences. Selection of patients wit...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Adrian Covic, Paul Gusbeth-Tatomir Tags: Symposium on Renovascular Disease Source Type: journals
Renal Artery Stenosis: Imaging Options, Pitfalls, and ConcernsEmail this article to a colleague.
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Abstract: Renal artery stenosis can be diagnosed with multiple imaging modalities, each one having different risk vs accuracy tradeoffs. Catheter angiography with pressure gradient measurements is the definitive gold standard but also the most invasive and thus reserved primarily for imaging at the time of renal revascularization. Ultrasonography is the safest and least expensive but also the least accurate and most operator-dependent. Contrast-enhanced computed tomographic angiography and magnetic resonance angiography are intermediate (between ultrasound and catheter angiography) with respect to accuracy and expense. Exc...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Hong Lei Zhang, Thomas A. Sos, Priscilla A. Winchester, Jing Gao, Martin R. Prince Tags: Symposium on Renovascular Disease Source Type: journals
Timing and Selection for Renal Revascularization in an Era of Negative Trials: What to Do?Email this article to a colleague.
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Abstract: Management of atherosclerotic renal artery stenosis has become more complex with advances in both medical therapy and endovascular procedures. Results from recent trials fail to demonstrate major benefits of endovascular stenting in addition to optimal medical therapy. The general applicability of these results to many patients is limited by short-term follow-up and selection biases in recruitment. Many patients at highest risk were excluded from these studies and some were included with trivial lesions. Identification of patients with hemodynamically significant lesions remains a challenge and has led to more st...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Stephen C. Textor, Michael M. McKusick, Sanjay Misra, James Glockner Tags: Symposium on Renovascular Disease Source Type: journals
Management of Renal Artery Stenosis: The Case for Intervention, Defending Current Guidelines, and Screening (Drive-By) Renal Angiography at the Time of CatheterizationEmail this article to a colleague.
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Abstract: There is little debate that an untreated significant obstruction of blood flow to the kidney, most often due to atherosclerosis, is potentially hazardous to the health of patients. The treatment of atherosclerotic renovascular disease has evolved over the past 20 years from open surgery with its inherent morbidity and risk of mortality to percutaneous endovascular treatment with stents. The current debate is on the question of which patients are offered any additional advantage by revascularization for renal artery stenosis over medications alone. The primary issue is patient selection, including the most appropr...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Christopher J. White Tags: Symposium on Renovascular Disease Source Type: journals
Cardiovascular Morbidity and Mortality and Renal Artery StenosisEmail this article to a colleague.
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Abstract: Renal artery stenosis (RAS) is a common manifestation of atherosclerosis and is associated with many other atherosclerotic conditions. Cardiovascular morbidity and mortality is increased among patients with RAS. This increase is likely due in part to the associated disease states; however, RAS itself may also contribute. Current strategies to limit cardiovascular morbidity and mortality in RAS include various pharmacologic interventions targeting both RAS atherosclerosis in general. Additionally, revascularization has been advocated; however, clear data are lacking. Ongoing clinical trials such as the Cardiovascu...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: William R. Colyer, Christopher J. Cooper Tags: Symposium on Renovascular Disease Source Type: journals
The Role of Renal Sympathetic Nerves in Hypertension: Has Percutaneous Renal Denervation Refocused Attention on Their Clinical Significance?Email this article to a colleague.
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Abstract: Renal sympathetic efferent and afferent nerves, which lie within and immediately adjacent to the wall of the renal artery, contribute to the pathogenesis of hypertension. Because the causative factors of hypertension change over time, denervation of both efferent and afferent nerves should result in long-term attenuation of the hypertension. The importance of the renal nerves in patients with hypertension can now be defined with the novel development of percutaneous minimally invasive renal denervation from within the renal artery using radiofrequency energy as a therapeutic strategy. Studies thus far show that c...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Richard E. Katholi, Krishna J. Rocha-Singh Tags: Symposium on Renovascular Disease Source Type: journals
Flash Pulmonary EdemaEmail this article to a colleague.
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Abstract: Flash pulmonary edema (FPE) is a general clinical term used to describe a particularly dramatic form of acute decompensated heart failure. Well-established risk factors for heart failure such as hypertension, coronary ischemia, valvular heart disease, and diastolic dysfunction are associated with acute decompensated heart failure as well as with FPE. However, endothelial dysfunction possibly secondary to an excessive activity of renin-angiotensin-aldosterone system, impaired nitric oxide synthesis, increased endothelin levels, and/or excessive circulating catecholamines may cause excessive pulmonary capillary per...
Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Authors: Stefano F. Rimoldi, Melana Yuzefpolskaya, Yves Allemann, Franz Messerli Tags: Special Article Source Type: journals
Table of ContentsEmail this article to a colleague.
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Source: Progress in Cardiovascular Diseases - November 1, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
[Editorial]Email this article to a colleague.
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PMID: 19914414 [PubMed - in process]
Source: Annales de Cardiologie et d'Angeiologie - November 1, 2009 Category: Cardiology Authors: Barnay C Tags: Ann Cardiol Angeiol (Paris) Source Type: journals
Renoprotective and Potassium Sparing Effects of Low Dose Dopamine in Acute Decompensated Heart Failure: Preliminary Results of the Dopamine in Acute Decompensated Heart Failure (DAD-HF) TrialEmail this article to a colleague.
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Background: Worsening renal function (WRF) and hypokalemia related to diuretic use for acute decompensated heart failure (ADHF) are common and portend poor prognosis. Low dose dopamine infusion improves renal perfusion. Whether dopamine infusion improves diuresis and/or reduces renal complication in ADHF is not known.
Source: Journal of Cardiac Failure - October 31, 2009 Category: Cardiology Authors: Gregory Giamouzis, Javed Butler, Randall C. Starling, Carsten Tschöpe, Dirk Westermann, Dimitrios Economou, George Karayannis, Charalambos Parisis, Dimitrios Rovithis, John Nastas, Themistoklis Kirlidis, Themistoklis Tsaknakis, John Skoularigis, Filippos Tags: Late-Breaking Clinical Trial Presentations Source Type: journals
Calendar of EventsEmail this article to a colleague.
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Source: Journal of Cardiac Failure - October 31, 2009 Category: Cardiology Tags: Calendar of Events Source Type: journals
Editorial BoardEmail this article to a colleague.
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Source: Journal of Cardiac Failure - October 31, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
MastheadEmail this article to a colleague.
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Source: Journal of Cardiac Failure - October 31, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Table of ContentsEmail this article to a colleague.
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Source: Journal of Cardiac Failure - October 31, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Information for AuthorsEmail this article to a colleague.
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Source: Journal of Cardiac Failure - October 31, 2009 Category: Cardiology Tags: Frontmatter Source Type: journals
Effect of Rolofylline, a Selective Adenosine A1 Receptor Antagonist, in Patients Hospitalized for Acute Decompensated Heart Failure and Renal Impairment: Findings from the PROTECT StudyEmail this article to a colleague.
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Context: Patients with acute heart failure (AHF) often present with or develop worsening renal function (WRF) and diuretic resitance during treatment (often termed “cardiorenal syndromeâ€□), with poorer subsequent in-hospital and post-discharge outcomes. Experimental and clinical studies suggest that counter- regulatory responses mediated by adenosine are mechanistically involved.
Source: Journal of Cardiac Failure - October 31, 2009 Category: Cardiology Authors: M. Christopher O'Connor, PROTET Study and Investigators Tags: Late-Breaking Clinical Trial Presentations Source Type: journals
