Cardiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 9.
The tail of Cx43: its crucial protective role in acute myocardial infarction
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Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Wang, Y., Cheng, Y. Tags: EDITORIALS Source Type: journals
Vasoconstriction: tightening the noose through MMPsEmail this article to a colleague.
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Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Isenberg, J. S., Shiva, S. Tags: EDITORIALS Source Type: journals
Endocannabinoid signalling as an anti-inflammatory therapeutic target in atherosclerosis: does it work?Email this article to a colleague.
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Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Immenschuh, S. Tags: EDITORIALS Source Type: journals
'Leaky' ryanodine receptors and sudden cardiac deathEmail this article to a colleague.
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Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Brown, D. A., Cascio, W. E. Tags: EDITORIALS Source Type: journals
Targeting calcium transport in ischaemic heart diseaseEmail this article to a colleague.
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Ischaemic heart disease (IHD) is the leading cause of morbidity and mortality worldwide. While timely reperfusion of acutely ischaemic myocardium is essential for myocardial salvage, it leads to a unique type of injury known as ‘myocardial ischaemia/reperfusion (I/R) injury’. Growing evidence suggests that a defect in myocardial Ca2+ transport system with cytosolic Ca2+ overload is a major contributor to myocardial I/R injury. Progress in molecular genetics and medicine in past years has clearly demonstrated that modulation of Ca2+ handling pathways in IHD could be cardioprotective. The potential benefits of th...
Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Talukder, M.A. H., Zweier, J. L., Periasamy, M. Tags: REVIEWS Source Type: journals
Interleukin 8 and cardiovascular diseaseEmail this article to a colleague.
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Since the establishment of the inflammatory basis of atherosclerosis, several pro- or anti-inflammatory agents have been examined as potential mediators of the biochemical pathways of lesion formation. Interleukin (IL)-8 was first characterized in 1987. Since then, knowledge regarding its role in leucocyte trafficking and activation has advanced rapidly, especially in the field of cardiovascular disease. In the scientific literature, there is sufficient evidence to support beyond any doubt the involvement of IL-8 in the establishment and preservation of the inflammatory micro-environment of the insulted vascular wall. Howe...
Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Apostolakis, S., Vogiatzi, K., Amanatidou, V., Spandidos, D. A. Tags: REVIEWS Source Type: journals
Cx43 CT domain influences infarct size and susceptibility to ventricular tachyarrhythmias in acute myocardial infarctionEmail this article to a colleague.
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Conclusion
Loss of the regulatory domain of Cx43 leads to an increase in infarct size and increased susceptibility to arrhythmias following acute coronary occlusion.
Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Maass, K., Chase, S. E., Lin, X., Delmar, M. Tags: ORIGINAL ARTICLES Source Type: journals
Maintenance of adrenergic vascular tone by MMP transactivation of the EGFR requires PI3K and mitochondrial ATP synthesisEmail this article to a colleague.
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Conclusion
These data suggest that the maintenance of adrenergic vascular tone by the MMP–EGFR pathway requires PI3K activation and ATP synthesis. Further, our data support the view that elevated levels of GPCR agonists exaggerate the MMP transactivation of EGFR response and contribute to enhanced vascular tone and development of cardiovascular disease such as hypertension.
Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Nagareddy, P. R., Chow, F. L., Hao, L., Wang, X., Nishimura, T., MacLeod, K. M., McNeill, J. H., Fernandez-Patron, C. Tags: ORIGINAL ARTICLES Source Type: journals
CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophagesEmail this article to a colleague.
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Conclusion
CB1 promotes pro-inflammatory responses of macrophages through ROS production, which is negatively regulated by CB2 through Rap1 activation. Blocking CB1 together with selective activation of CB2 may suppress pro-inflammatory responses of macrophages.
Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Han, K. H., Lim, S., Ryu, J., Lee, C.-W., Kim, Y., Kang, J.-H., Kang, S.-S., Ahn, Y. K., Park, C.-S., Kim, J. J. Tags: ORIGINAL ARTICLES Source Type: journals
Redox modification of ryanodine receptors underlies calcium alternans in a canine model of sudden cardiac deathEmail this article to a colleague.
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Conclusion
Redox modulation of RyRs promotes generation of Ca2+ alternans by enhancing the steepness of the Ca2+ release–load relationship and thereby providing a substrate for post-MI arrhythmias.
Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Belevych, A. E., Terentyev, D., Viatchenko-Karpinski, S., Terentyeva, R., Sridhar, A., Nishijima, Y., Wilson, L. D., Cardounel, A. J., Laurita, K. R., Carnes, C. A., Billman, G. E., Gyorke, S. Tags: ORIGINAL ARTICLES Source Type: journals
Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in miceEmail this article to a colleague.
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Conclusion
Cardiac overexpression of a Ca2+-channel β2a-subunit alone is sufficient to induce Ca2+-channel properties characteristic of chronic human heart failure. β2a-overexpression by itself did not induce cardiac hypertrophy or contractile dysfunction, but aggravated the development of arrhythmia and fibrosis in Cav1.2-transgenic mice.
Source: Cardiovascular Research - November 16, 2009 Category: Cardiology Authors: Beetz, N., Hein, L., Meszaros, J., Gilsbach, R., Barreto, F., Meissner, M., Hoppe, U. C., Schwartz, A., Herzig, S., Matthes, J. Tags: ORIGINAL ARTICLES Source Type: journals
AHA: EKG Pattern Linked to Cardiac Death in General Population (CME/CE)Email this article to a colleague.
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ORLANDO (MedPage Today) -- An early repolarization pattern in the inferior leads of a standard electrocardiogram is associated with an increased risk of cardiac death in middle-age individuals, Finnish researchers found.
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
Duke Research Institute launches study to better treat a-fibEmail this article to a colleague.
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To better study treatments and patient outcomes linked to atrial fibrillation, the Duke Clinical Research Institute has initiated the Outcomes Registry for Better informed Treatment of Atrial Fibrillation.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
Duke launches study to better treat a-fibEmail this article to a colleague.
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To better study treatments and patient outcomes linked to atrial fibrillation, the Duke Clinical Research Institute has initiated the Outcomes Registry for Better informed Treatment of Atrial Fibrillation.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
Plasma renin activity associated with cardiovascular events and mortality in HOPEEmail this article to a colleague.
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Patients with elevated baseline plasma renin activity levels had a twofold increased risk of total or cardiovascular mortality compared with those with low levels, and the strength of the association persisted after multiple adjustments, including the HOPE score, CRP, and BNP.
Source: theHeart.org - November 16, 2009 Category: Cardiology Source Type: info
AHA: Longer Perspective Moves Most from Low to High CV Risk (CME/CE)Email this article to a colleague.
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ORLANDO (MedPage Today) -- Assessing only 10-year Framingham coronary risk may be misleading for the majority of patients, researchers found.
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
Edwards Lifesciences grants $4.6 million for CV research in 2009Email this article to a colleague.
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Edwards Lifesciences will award a total of $4.6 million in 2009 for programs and facilities that work towards progressing research and innovative treatment solutions for patients suffering from cardiovascular disease.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
Medical device correction issued for Cardiac Science AEDsEmail this article to a colleague.
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AEDs manufactured by Cardiac Science are undergoing a nationwide voluntary medical device correction because of the potential failure of these devices to deliver therapy during use.
Source: theHeart.org - November 16, 2009 Category: Cardiology Source Type: info
Intra-Nasal Cooling During Resuscitation May Save More Brains After Cardiac ArrestEmail this article to a colleague.
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A new study involving emergency centres in Europe found that using a new portable device in situ to spray a rapidly evaporating coolant into the nasal cavity within minutes of the heart arresting resulted in faster and earlier cooling and a higher chance of saving the brain of patients compared to waiting until they are in the emergency room (ER).
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Medical Devices / Diagnostics Source Type: news
AHA: ACE Inhibitor Fails in Single Ventricle Infants (CME/CE)Email this article to a colleague.
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ORLANDO (MedPage Today) -- For infants with single ventricle congenital heart defects, ACE inhibition doesn't improve growth or heart remodeling, according to a randomized trial.
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
AHA: Men at Higher Risk of Sudden Cardiac Death (CME/CE)Email this article to a colleague.
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ORLANDO (MedPage Today) -- Middle-aged men are about three times more likely to suffer sudden cardiac death than women, researchers found.
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
Thomson Reuters' 2009 Top 100 CV hospitals winners improve care, cut costsEmail this article to a colleague.
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Thomson Reuters today released its annual study identifying the 100 U.S. hospitals that set the nation's benchmarks for inpatient cardiovascular care, examining the performance of 971 hospitals by analyzing outcomes for patients diagnosed with heart failure and heart attacks.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
AHA: ECG Cost-Effective for Screening Student Athletes (CME/CE)Email this article to a colleague.
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ORLANDO (MedPage Today) -- Cost issues needn't keep electrocardiograms out of most schools' efforts to screen student athletes for potentially fatal heart problems any longer, researchers said.
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
AHA: Heart Failure Linked to Poor Exercise Response (CME/CE)Email this article to a colleague.
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ORLANDO (MedPage Today) -- Heart failure patients with a normal left ventricular ejection fraction have an impaired heart rate response to exercise compared with healthy individuals, researchers found.
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
REPLACE registry finds 15.3% six-month complication rate with pacer and ICD lead replacementsEmail this article to a colleague.
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The REPLACE registry finds "sobering" comprehensive risk rates with pacemaker and ICD upgrades.
Source: theHeart.org - November 16, 2009 Category: Cardiology Source Type: info
RE-LY on dabigatran for stroke prevention in atrial fibrillationEmail this article to a colleague.
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Consistent reductions in stroke and major bleeding events are achieved with dabigatran when compared with dose-adjusted warfarin in patients with atrial fibrillation. This is irrespective of the International Normalized Ratios achieved.
Source: MedWire News - Cardiology - November 16, 2009 Category: Cardiology Source Type: news
Hip fracture a significant concern in HF patientsEmail this article to a colleague.
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Hip fracture is particularly common and a significant cause of mortality in heart failure patients, US researchers have found.
Source: MedWire News - Heart Failure - November 16, 2009 Category: Cardiology Source Type: news
PRINCE: Prehospital intranasal cooling after cardiac arrest feasible, may improve survivalEmail this article to a colleague.
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A device that allows therapeutic hypothermia to begin in the field has been shown to be safe and its use feasible in treating out-of-hospital cardiac arrest.
Source: theHeart.org - November 16, 2009 Category: Cardiology Source Type: info
Abbott Statement On ARBITER 6 - HALTS Results And Abbott's Niaspan (Niacin Extended-Release)Email this article to a colleague.
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Results from the investigator-initiated ARBITER 6 - HALTS study showed patients at high cardiovascular risk had significant regression of atherosclerosis after 8 and 14 months of therapy with Abbott's Niaspan® (niacin extended-release tablets) plus a statin, the study's primary endpoint.
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
Physicans awarded more than $92 million by CMSEmail this article to a colleague.
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More than 85,000 physicians and healthcare professionals, who properly reported data regarding Medicare services to the Center for Medicaid & Medicare Services (CMS), reaped more than $92 million in incentives in 2008 under the Physician Quality Reporting Initiative.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
Physicians awarded more than $92 million by CMSEmail this article to a colleague.
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More than 85,000 physicians and healthcare professionals, who properly reported data regarding Medicare services to the Center for Medicaid & Medicare Services (CMS), reaped more than $92 million in incentives in 2008 under the Physician Quality Reporting Initiative.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
Intestinal Sleeve May Improve Glycemic Control (CME/CE)Email this article to a colleague.
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Noninvasively implanting a sleeve in the small intestine just beyond the stomach quickly improves glycemic control in obese diabetes patients, researchers say.
Source: MedPage Today Cardiovascular - November 16, 2009 Category: Cardiology Source Type: news
Study: Catheter-directed thrombolysis first option for pulmonary embolismEmail this article to a colleague.
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The use of catheter-directed thrombolysis saves lives and should be considered a first-line treatment option for massive pulmonary embolism, according to a study in the November issue of the Journal of Vascular and Interventional Radiology.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
Check your pulseEmail this article to a colleague.
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Our new pulse check campaign is aimed at helping find people at hidden risk of stroke
Source: BHF National News - November 16, 2009 Category: Cardiology Source Type: consumer
CPR saves livesEmail this article to a colleague.
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We say giving emergency life support is still the right thing to do
Source: BHF National News - November 16, 2009 Category: Cardiology Source Type: consumer
The Medicines Company's Full Analysis Of CHAMPION Phase III Data Shows Cangrelor Significantly Improves Patient Outcomes Following PCIEmail this article to a colleague.
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The Medicines Company (NASDAQ: MDCO) announced the data from 13,941 patients treated in the discontinued CHAMPION Phase III program of cangrelor.
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
AHA: Cangrelor fails to become a CHAMPION in two randomized, controlled trialsEmail this article to a colleague.
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Orlando, Fla.—The new, reversible antiplatelet drug cangrelor was not superior over clopidogrel in reducing the composite of death, MI or ischemic revascularization 48 hours after PCI, nor did the investigative drug prove superior over placebo for combined endpoint of MI, all-cause mortality and revascularization. Yet, the drug may have some benefits for stent thrombosis. Two randomized, controlled trials demonstrated these results, which were presented Sunday at the American Heart Association late breaking clinical trials session.
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news
'Scaffolding' Protein Changes In Heart Strengthen Link Between Alzheimer's Disease And Chronic Heart FailureEmail this article to a colleague.
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A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer's disease and chronic heart failure, two of the 10 leading causes of death in the United States. The international team of biochemists and cardiologists say they have identified three changes in the chemical make-up of a key structural protein, called desmin, in heart muscle cells in dogs.
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Alzheimer's / Dementia Source Type: news
Health Policy Research Round Up - Medicare And MassachusettsEmail this article to a colleague.
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Robert Wood Johnson Foundation: The Secrets of Massachusetts' Success - "By the summer of 2008, less than two years after Massachusetts' health reform law became effective, only 2.6 percent of state residents were uninsured - the lowest proportion ever recorded for any state.
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Medicare / Medicaid / SCHIP Source Type: news
Link Between Fat Around Organs And Decreased Heart FunctionEmail this article to a colleague.
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Researchers from Boston University School of Medicine (BUSM) have shown that fat collection in different body locations, such as around the heart and the aorta and within the liver, are associated with certain decreased heart functions. The study, which appears on-line in Obesity, also found that measuring a person's body mass index (BMI) does not reliably predict the amount of undesired fat in and around these vital organs.
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Heart Disease Source Type: news
Tiny Particles Can Deliver Antioxidant Enzyme To Injured Heart CellsEmail this article to a colleague.
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Researchers at Emory University and the Georgia Institute of Technology have developed microscopic polymer beads that can deliver an antioxidant enzyme made naturally by the body into the heart. Injecting the enzyme-containing particles into rats' hearts after a simulated heart attack reduced the number of dying cells and resulted in improved heart function days later.
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
New Mechanism Identified For Beneficial Effects Of Aspirin In Cardiovascular DiseaseEmail this article to a colleague.
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On Sunday, November 15, 2009, Florida Atlantic University (FAU) researcher Charles H. Hennekens, M.D., the first Sir Richard Doll Research Professor in the Charles E. Schmidt College of Biomedical Science will present at the American Heart Association's Annual Scientific Sessions meeting in Orlando, FL, the first data in humans to show that all doses of aspirin used in clinical practice increase nitric oxide.
Source: Cardiovascular / Cardiology News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news
Columbia's 2009 Naomi Berrie Award For Diabetes ResearchEmail this article to a colleague.
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Columbia University Medical Center presentED the 2009 Naomi Berrie Awards to a nationally recognized diabetes researcher, and a promising young investigator, for their outstanding achievements in diabetes research. The Award for Outstanding Achievement in Diabetes Research WENT to Richard Nathan Bergman, Ph.D, Professor and Chair of the Department of Physiology & Biophysics at the Keck School of Medicine of the University of Southern California (USC). Dr.
Source: Cholesterol News From Medical News Today - November 16, 2009 Category: Cardiology Tags: Diabetes Source Type: news
Clinical Trial Summary: Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT — Presented at AHA 2009)Email this article to a colleague.
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Although erythropoiesis-stimulating agents (ESAs) are widely used in patients with anemia and chronic kidney disease (CKD) who are not on dialysis, randomized data to support this approach are not available. The TREAT trial sought to test the hypothesis that the use of ESAs in patients with diabetes. . .
Source: Cardiosource - November 16, 2009 Category: Cardiology Source Type: organizations
FDA OKs Menstrual Drug LystedaEmail this article to a colleague.
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Title: FDA OKs Menstrual Drug LystedaCategory: Health NewsCreated: 11/16/2009 11:45:00 AMLast Editorial Review: 11/16/2009 11:45:22 AM
Source: MedicineNet Cholesterol General - November 16, 2009 Category: Cardiology Source Type: consumer
Alternative to Warfarin May Cut Risk of BleedingEmail this article to a colleague.
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Title: Alternative to Warfarin May Cut Risk of BleedingCategory: Health NewsCreated: 11/15/2009 4:10:00 PMLast Editorial Review: 11/16/2009
Source: MedicineNet Cholesterol General - November 16, 2009 Category: Cardiology Source Type: consumer
Sudden Cardiac Death Much More Likely to Strike MenEmail this article to a colleague.
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Title: Sudden Cardiac Death Much More Likely to Strike MenCategory: Health NewsCreated: 11/15/2009 4:10:00 PMLast Editorial Review: 11/16/2009
Source: MedicineNet Cholesterol General - November 16, 2009 Category: Cardiology Source Type: consumer
FDA OKs Menstrual Drug LystedaEmail this article to a colleague.
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Title: FDA OKs Menstrual Drug LystedaCategory: Health NewsCreated: 11/16/2009 11:45:00 AMLast Editorial Review: 11/16/2009 11:45:22 AM
Source: MedicineNet Heart General - November 16, 2009 Category: Cardiology Source Type: consumer
Experts Urge School Screening of Athletes' HeartsEmail this article to a colleague.
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Title: Experts Urge School Screening of Athletes' HeartsCategory: Health NewsCreated: 11/15/2009 12:10:00 PMLast Editorial Review: 11/16/2009
Source: MedicineNet Heart General - November 16, 2009 Category: Cardiology Source Type: consumer
Rapid Cooling Might Help Heart Attack PatientsEmail this article to a colleague.
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Title: Rapid Cooling Might Help Heart Attack PatientsCategory: Health NewsCreated: 11/15/2009 4:10:00 PMLast Editorial Review: 11/16/2009
Source: MedicineNet Heart General - November 16, 2009 Category: Cardiology Source Type: consumer
