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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 34.

For Adults With Diabetes And Heart Disease, Cardiac Bypass Surgery Found To Be Superior To Non-Surgical Procedure
Adults with diabetes and multi-vessel coronary heart disease who underwent cardiac bypass surgery had better overall heart-related outcomes than those who underwent an artery-opening procedure to improve blood flow to the heart muscle, according to the results from an international study. The research was supported by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health...
Source: Health News from Medical News Today - November 6, 2012 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

Cytoreductive Surgery and Intraoperative Administration of Paclitaxel-loaded Expansile Nanoparticles Delay Tumor Recurrence in Ovarian Carcinoma
Conclusions Expansile nanoparticles readily enter human ovarian tumor cells and localize to sites of tumor in vivo with pax-eNP cytotoxicity resulting in superior inhibition of locoregional tumor recurrence following cytoreductive surgery. Content Type Journal ArticleCategory Gynecologic OncologyPages 1-10DOI 10.1245/s10434-012-2696-5Authors Denis Gilmore, Division of Thoracic Surgery, Department of Surgery, Brigham and Women’s Hospital, Boston, MA, USAMorgan Schulz, Division of Thoracic Surgery, Department of Surgery, Brigham and Women’s Hospital, Boston, MA, USARong Liu, Division of Thoracic Su...
Source: Annals of Surgical Oncology - November 6, 2012 Category: Cancer & Oncology Tags: Annals of Surgical Oncology Source Type: research

A Contemporary View of Diagnostic Cardiac Catheterization and Percutaneous Coronary Intervention in the United States A Report From the CathPCI Registry of the National Cardiovascular Data Registry, 2010 Through June 2011
This study sought to provide a report to the public of data from the CathPCI Registry of the National Cardiovascular Data Registry.BackgroundThe CathPCI Registry collects data from approximately 85% of the cardiac catheterization laboratories in the United States.MethodsData were summarized for 6 consecutive calendar quarters beginning January 1, 2010, and ending June 30, 2011. This report includes 1,110,150 patients undergoing only diagnostic cardiac catheterization and 941,248 undergoing percutaneous coronary intervention (PCI).ResultsSome notable findings include, for example, that on-site cardiac surgery was not availa...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 6, 2012 Category: Cardiology Source Type: research

The Risk of Adverse Cardiac and Bleeding Events Following Noncardiac Surgery Relative to Antiplatelet Therapy in Patients With Prior Percutaneous Coronary Intervention
Noncardiac surgery (NCS) may be required within the first year after percutaneous coronary intervention (PCI) in approximately 4% of patients and is the second most common reason for premature discontinuation of antiplatelet therapy (APT),which may, in turn, increase the risk of perioperative ischemic events, particularly stent thrombosis. Its continuation may increase the risk of perioperative bleeding. We review current information on the incidence of these events, particularly related to APT, describe potentially useful strategies to minimize the risks of adverse outcomes, and provide recommendations on APT use.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - November 6, 2012 Category: Cardiology Source Type: research

Pain After Median Sternotomy: Collateral Damage or Mitigatable Byproduct?
Conclusion Postoperative sternal pain is related to the degree of misalignment of the sternal halves. It would be appropriate for surgeons to approximate the sternal halves accurately to decrease the postoperative sternal wound pain in the first place. PMID: 23132359 [PubMed - as supplied by publisher]
Source: The Thoracic and Cardiovascular Surgeon - November 6, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Moon MH, Kang JK, Kim HW, Jo KH, Choi SH, Song H Tags: Thorac Cardiovasc Surg Source Type: research

Gender-Dependent Differences in Patients Undergoing Tricuspid Valve Surgery.
Conclusions We were not able to find significant gender-dependent differences in the postoperative outcome after isolated TV surgery, but there seem to be demographic gender-dependent differences regarding the reasons for TV surgery, which could influence the treatment of patients. PMID: 23132360 [PubMed - as supplied by publisher]
Source: The Thoracic and Cardiovascular Surgeon - November 6, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Pfannmueller B, Eifert S, Seeburger J, Misfeld M, Borger M, Mende M, Garbade J, Mohr F Tags: Thorac Cardiovasc Surg Source Type: research

RCT: Intraoperative high-dose dexamethasone for cardiac surgery
Source: JAMA Area: News According to a study featured in the Journal of the American Medical Association (JAMA), although commonly given in the hope of attenuating the inflammatory response to cardiac bypass surgery, intraoperative high-dose dexamethasone does not reduce major adverse events in the first 30 days following surgery. Despite evidence that routine corticosteroid use can prevent major adverse events in cardiovascular surgery, prophylactic corticosteroids are often administered to attenuate the inflammatory response to cardiopulmonary bypass and surgical trauma. Researchers therefore condu...
Source: NeLM - News - November 6, 2012 Category: Drugs & Pharmacology Source Type: news

RCT: Peri-operative fish oil supplementation in cardiac surgery patients does not prevent postoperative AF
Source: JAMA Area: News According to a study published early online in the Journal of the American Medical Association (JAMA), perioperative supplementation with omega-3 fatty acids in patients undergoing cardiac surgery does not reduce the risk of postoperative atrial fibrillation (AF). Researchers conducted The Omega-3 Fatty Acids for Prevention of Post-operative Atrial Fibrillation (OPERA) study to determine whether perioperative long-chain omega-3-polyunsaturated fatty acids (PUFAs) supplementation reduces postoperative AF. The double-blind, placebo-controlled trial involved a total of 1516 patie...
Source: NeLM - Cardiovascular Medicine - November 6, 2012 Category: Cardiology Source Type: news

Implantable Cardioverter Defibrillators in Patients with Valvular Cardiomyopathy
Conclusion: Patients with VCM who undergo ICD implantation for SCD prevention have similar appropriate ICD discharge rates and mortality as do those with ICM and DCM. These data are hypothesis generating and deserve confirmation with large‐scale prospective studies. (J Cardiovasc Electrophysiol, Vol. pp. 1‐7)
Source: Journal of Cardiovascular Electrophysiology - November 6, 2012 Category: Cardiology Authors: ALFRED G. VALLES, FARHAN J. KHAWAJA, BERNARD J. GERSH, MAURICE ENRIQUEZ‐SARANO, PAUL A. FRIEDMAN, SOON J. PARK, DAVID O. HODGE, YONG‐MEI CHA Source Type: research

Electroanatomic Characterization and Ablation Outcome of Nonlesion Related Left Atrial Macroreentrant Tachycardia in Patients Without Obvious Structural Heart Disease
Conclusion: Extensive scarring of the LA formed arrhythmogenic substrates of LAMRT in this group of patients. Ablation targeting these narrow, slow conduction zones eliminated atrial tachycardia in all patients. (J Cardiovasc Electrophysiol, Vol. pp. 1‐7)
Source: Journal of Cardiovascular Electrophysiology - November 6, 2012 Category: Cardiology Authors: JINLIN ZHANG, CHENG TANG, YONGHUA ZHANG, HONGWEI HAN, ZHEN LI, XI SU Source Type: research

Effect of Novel Limited-Spectrum MMP Inhibitor XL784 in Abdominal Aortic Aneurysms
Background: Inhibiting the growth of small abdominal aortic aneurysms (AAAs) is a clinically valuable goal and fills an important therapeutic void. Based on studies in animals and humans, inhibition of the activity of elastolytic matrix metalloproteinases (MMPs) has the potential to slow AAA expansion and limit morbidity and the need for surgery. Previous attempts to make use of the synthetic MMP inhibitors in the treatment of chronic conditions have been limited by intolerable side effects. The limited-spectrum synthetic MMP inhibitor, XL784, was well tolerated and devoid of side-effects associated with other nonspecific ...
Source: Journal of Cardiovascular Pharmacology and Therapeutics - November 6, 2012 Category: Cardiology Authors: Ennis, T., Jin, J., Bartlett, S., Arif, B., Grapperhaus, K., Curci, J. A. Tags: Experimental Studies Source Type: research

Curcumin Attenuates Cardiopulmonary Bypass-Induced Lung Oxidative Damage in Rats
Conclusions: Curcumin has the potential to provide protection from CPB-induced lung damage reflected in the expression of oxidative stress markers. The antioxidant effect of curcumin may be partly related to upregulation of HO-1.
Source: Journal of Cardiovascular Pharmacology and Therapeutics - November 6, 2012 Category: Cardiology Authors: Liu, K., Chen, H.-L., Huang, H., Jing, H., Dong, G.-H., Wu, H.-W., You, Q.-S. Tags: Experimental Studies Source Type: research

Diabetes severely affects attentional performance after coronary artery bypass grafting
Conclusions: Diabetes may have an impact on cognitive performance after CABG. More severe deficits in alertness may point to underlying microvascular disease.
Source: Journal of Cardiothoracic Surgery - November 6, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Jens-Holger KrannichTherese TobiasJens BroscheitRainer LeyhWolfgang Müllges Source Type: research

Intracranial aneurysm in childhood and interrupted aortic arch
Conclusion Surgical or endovascular obliteration remains the main therapy for intracranial aneurysms. Accompanying systemic diseases such as interrupted aortic arch challenge the management of both diseases. Content Type Journal ArticleCategory Case-Based UpdatePages 1-5DOI 10.1007/s00381-012-1959-6Authors Alp Özgün Börcek, Division of Pediatric Neurosurgery, Gazi University Medical School, Beşevler, 06500 Ankara, TurkeyEmrah Egemen, Division of Pediatric Neurosurgery, Gazi University Medical School, Beşevler, 06500 Ankara, TurkeyGünhan Güngör, Division of Pediatric Neurosurgery, Gazi Univers...
Source: Child's Nervous System - November 5, 2012 Category: Pediatrics Tags: Child's Nervous System Source Type: research

Fishbone penetration of the thoracic esophagus with prolonged asymptomatic impaction within the aorta
A 54-year-old man with fishbone penetration of the thoracic esophagus and mediastinal hematoma was successfully managed with conservative treatment. Six-month follow-up computed tomography (CT) revealed migration of the fishbone into the aorta; however, the patient was asymptomatic and refused surgery. Six years later, CT showed persistent impaction of the fishbone within the aorta, but the patient was healthy. To our knowledge, this is the first reported case of serial CT documentation of fishbone penetration of the esophagus with migration into and prolonged asymptomatic impaction within the aorta.
Source: Journal of Vascular Surgery - November 5, 2012 Category: Surgery Authors: Sheung-Fat Ko, Hung-I Lu, Shu-Hang Ng, Chia-Te Kung Tags: Case reports Source Type: research

Perivascular innate immune events modulate early murine vein graft adaptations
Conclusions: Perivascular and distant inflammatory challenges potentiate the magnitude and duration of inflammatory responses in the early vein graft wall, negatively modulating wall adaptations, and thus, potentially contribute to vein graft failure. Furthermore, surgery activates innate immunity in adipose tissue, which is augmented (regionally > systemically) by LPS. Modulation of these local and distant inflammatory signaling networks stands as a potential strategy to enhance the durability of vascular interventions such as vein grafts.Clinical Relevance: Vein graft failure is traditionally considered as a process driv...
Source: Journal of Vascular Surgery - November 5, 2012 Category: Surgery Authors: Binh T. Nguyen, Peng Yu, Ming Tao, Shuai Hao, Tianyu Jiang, C. Keith Ozaki Tags: Basic research studies Source Type: research

Pro: Etomidate Is the Ideal Induction Agent for a Cardiac Anesthetic
POSTINDUCTION HYPOTENSION has been associated with increased morbidity and mortality. Patients who experienced ≥1 5-minute episode of hypotension after induction of general anesthesia had a 13.3% increase in hospital length of stay and an 8.6% increase of death. Hypotension has been defined as a decrease in mean arterial pressure 40% decrease from baseline. In a recent study in patients treated with antiplatelet agents for cardiovascular comorbidities undergoing major noncardiac surgery, intraoperative hypotension was identified as 1 of 3 independent predictors of intraoperative myocardial ischemia and necrosis assessed ...
Source: Journal of Cardiothoracic and Vascular Anesthesia - November 5, 2012 Category: Anesthesiology Authors: Arne O. Budde, Berend Mets Tags: Pro and Con Source Type: research

The role of vascular endothelial growth factor-D in diagnosis of lymphangioleiomyomatosis (LAM)
Summary: Background: Definite diagnosis of lymphangioleiomyomatosis (LAM) depends on either transbronchial lung biopsy or video-assisted thoracic surgery, unless there is a history of chylothorax, kidney angiomyolipoma (AML), or tuberous sclerosis complex (TSC). Vascular endothelial growth factor-D (VEGF-D) was recently considered as a novel diagnostic marker for LAM. Herein, we evaluated diagnostic value of serum VEGF-D in LAM patients.Methods: Serum samples were obtained from 78 cases of LAM (50 definite and 28 probable LAM based on European Respiratory Society guidelines), and 40 healthy female volunteers. VEGF-D was me...
Source: Respiratory Medicine CME - November 5, 2012 Category: Respiratory Medicine Authors: Kai-Feng Xu, Peng Zhang, Xinlun Tian, Aiping Ma, Xue Li, Jiong Zhou, Ni Zeng, Yao-Song Gui, Zijian Guo, Ruie Feng, Weihong Zhang, Wei Sun, Baiqiang Cai Tags: Interstitial Lung Disease Source Type: research

Surgical techniques and early experience of endovascular treatment of complex thoracic aortic disease via minithoracotomy
Endovascular repair of chronic descending thoracic aortic diseases is now a widely used, feasible, and relatively safe treatment. Nevertheless, when traditional vascular access is not available, the procedure can become troublesome and must require an open surgery. The article describes the surgical technique of minithoracotomic access to ascending aorta for endovascular treatment of descending aorta and the results of our preliminary clinical experience.
Source: Journal of Vascular Surgery - November 5, 2012 Category: Surgery Authors: Igor Vendramin, Gianluca Piccoli, Daniele Gasparini, Ugolino Livi Tags: Vascular and endovascular techniques Source Type: research

Supraclavicular decompression for neurogenic thoracic outlet syndrome in adolescent and adult populations
Conclusions: Adolescents undergoing supraclavicular decompression for NTOS had more favorable preoperative characteristics and enhanced 3-month and 6-month functional outcomes than adults. Further study is needed to delineate the age-dependent and independent factors that promote optimal surgical outcomes for NTOS.
Source: Journal of Vascular Surgery - November 5, 2012 Category: Surgery Authors: Francis J. Caputo, Anna M. Wittenberg, Chandu Vemuri, Matthew R. Driskill, Jeanne A. Earley, Rahul Rastogi, Valerie B. Emery, Robert W. Thompson Tags: Clinical research studies Source Type: research

A modern experience with saccular aortic aneurysms
Conclusions: While SAA were not found to have a higher growth rate than their fusiform counterparts, both clinical and radiologic follow-up is necessary, as a significant number ultimately require surgical intervention. Further clinical research is necessary to determine the optimal management of SAA.
Source: Journal of Vascular Surgery - November 5, 2012 Category: Surgery Authors: Eric K. Shang, Derek P. Nathan, William W. Boonn, Ivan A. Lys-Dobradin, Ronald M. Fairman, Edward Y. Woo, Grace J. Wang, Benjamin M. Jackson Tags: Clinical research studies Source Type: research

Discussion
Dr Abbas Ardehali (Los Angeles, Calif). This is a relevant and important study in the field of thoracic transplantation. It tries to address the issue of why otherwise healthy donors have poor LV function when the heart is offered for transplantation, and in a broader sense it tries to address the issue of the donor shortage.
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Tags: Cardiothoracic Transplantation Source Type: research

Effect of cytokine hemoadsorption on brain death–induced ventricular dysfunction in a porcine model
Conclusions: Hemoadsorption of cytokines using an extracorporeal circuit attenuates brain death–induced ventricular dysfunction in a porcine model. Improvement in function generally correlates with trends in cytokine expression, but this relationship requires further investigation.
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Krasimira M. Mikhova, Creighton W. Don, Michael Laflamme, John A. Kellum, Michael S. Mulligan, Edward D. Verrier, David G. Rabkin Tags: Cardiothoracic Transplantation Source Type: research

Discussion
Dr Irving Kron (Charlottesville, Va). I must say I have a conflict of interest in that I am a primary investigator for the Cardiothoracic Surgical Network. I would like to congratulate the authors on an outstanding paper. They have been accurate and clear and discussed the issues with such an analysis. They have done a database study of >1000 patients with CIMR. This is a retrospective study with propensity matching. The findings were interesting. Patients with MVR had a 3% mortality versus 5% for MVP, and this was not significant. The 8-year survival was exactly the same. Based on these findings, it would seem that MVR i...
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Tags: Acquired Cardiovascular Disease Source Type: research

Mitral valve repair or replacement for ischemic mitral regurgitation? The Italian Study on the Treatment of Ischemic Mitral Regurgitation (ISTIMIR)
Objective: It is uncertain whether mitral valve replacement is really inferior to mitral valve repair for the treatment of chronic ischemic mitral regurgitation. This multicenter study aimed at providing a contribution to this issue.Methods: Of 1006 patients with chronic ischemic mitral regurgitation and impaired left ventricular function (ejection fraction
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Roberto Lorusso, Sandro Gelsomino, Enrico Vizzardi, Antonio D'Aloia, Giuseppe De Cicco, Fabiana Lucà, Orlando Parise, Gian Franco Gensini, Pierluigi Stefàno, Ugolino Livi, Igor Vendramin, Davide Pacini, Roberto Di Bartolomeo, Antonio Miceli, Egidio Varo Tags: Acquired Cardiovascular Disease Source Type: research

Discussion
Dr D. Craig Miller (Stanford, Calif). Dr Tsukui, welcome to Hawaii and the Western Thoracic Surgical. Very nice presentation, paper, and video. I have 2 comments and 2 questions. Number 1 is a comment. This was an elegant presentation, but we must remember that what you are calling “foldoplasty” is not new. It is actually a very old technique, analogous to what Dwight McGoon pioneered 50 years ago at the Mayo Clinic. What you are showing is very similar, but why are we trying to reincarnate these ancient McGoon techniques today? The McGoon “V-excision” repair had been abandoned everywhere, except at the Mayo Clini...
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Tags: Acquired Cardiovascular Disease Source Type: research

Early outcome of folding mitral valve repair technique without resection for mitral valve prolapse in 60 patients
Conclusions: Folding mitral valve repair is an easily fine-tuned technique with a pilot suture, which can be easily removed and repositioned, if unsatisfactory. This reversibility is a significant advantage of this technique. Long-term follow-up is necessary to assess the durability of this technique.
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Hiroyuki Tsukui, Nobuhiro Umehara, Hiroyuki Saito, Satoshi Saito, Kenji Yamazaki Tags: Acquired Cardiovascular Disease Source Type: research

Discussion
Dr Sean C. Grondin (Calgar, Alberta, Canada). This is an important article for thoracic surgeons. Many organizations are publishing guidelines on CT screening, as you mentioned, and it is a hot topic for discussion. There are a lot of resources at stake, so I appreciate your group trying to tackle this important question.
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic Surgery Source Type: research

Patterns of recurrence and second primary lung cancer in early-stage lung cancer survivors followed with routine computed tomography surveillance
Conclusions: Almost all second primary cancers and the majority of recurrences were detected by post-therapeutic surveillance computed tomography scan. The risk of recurrence for early-stage non–small cell lung cancer survivors persisted during the first 4 years after resection, and vigilance in surveillance should be maintained.
Source: The Journal of Thoracic and Cardiovascular Surgery - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Feiran Lou, James Huang, Camelia S. Sima, Joseph Dycoco, Valerie Rusch, Peter B. Bach Tags: General Thoracic Surgery Source Type: research

Hemothorax: Etiology, Diagnosis, and Management
This article reviews the etiology, diagnosis, and treatment of traumatic and spontaneous hemothorax in modern practice.
Source: Thoracic Surgery Clinics - November 5, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Stephen R. Broderick Source Type: research

Progression‐free survival of two cases of high‐risk neuroblastoma with refractory/relapsed disease following surgery alone
We report two high‐risk patients who remain progression‐free for more than 113 and 18 months following the diagnosis of refractory/relapsed disease who were treated with surgery alone. Complete resolution of a refractory thoracic mass and relapsed liver nodules was observed in one patient. The refractory/relapsed disease in the second patient has remained stable. In both cases, the tumor showed histologic evidence of neuroblastoma maturation. These cases demonstrate that refractory/relapsed neuroblastoma is clinically heterogeneous and highlight the need for better biomarkers to optimize patient care. Pediatr Blood Can...
Source: Pediatric Blood and Cancer - November 5, 2012 Category: Cancer & Oncology Authors: Elizabeth Sokol, Paul R. Haut, Yasmin Gosiengfiao, Kate Feinstein, Peter Pytel, Susan L. Cohn Tags: Brief Report Source Type: research

Magnetic Resonance Imaging in the Diagnosis and Surveillance of Thoracic Aortic Perigraft Seroma and Its Complications
Source: Vascular and Endovascular Surgery - November 4, 2012 Category: Surgery Authors: Chua, S. K., Azarisman, S. M., Glenie, T., Baillie, T., Teo, K. S., Worthley, S. G. Tags: Case Reports Source Type: research

Risk analysis of pulmonary resection for elderly patients with lung cancer
Conclusions Although CCI ≥ 2 was associated with poorer survival, it was not necessarily a risk factor of postoperative complications or PHS. Performing VATS when possible could reduce the incidence of postoperative complications and PHS in elderly patients. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00595-012-0401-8Authors Hideki Endoh, Department of Thoracic Surgery, Saku General Hospital, 197 Usuda, Saku, Nagano 384-0301, JapanRyohei Yamamoto, Department of Thoracic Surgery, Saku General Hospital, 197 Usuda, Saku, Nagano 384-0301, JapanYukitoshi Satoh, D...
Source: Surgery Today - November 3, 2012 Category: Surgery Tags: Surgery Today Source Type: research

[Pulmonary rehabilitation in patients with lung cancer.]
Abstract The paper presents current news on the possibilities of conducting rehabilitation of patients suffering from lung cancer. It presents the principles of conducting and contraindications for pulmonary rehabilitation for these patients according to current guidelines of American College of Sport Medicine. The methods of measuring exercise capacity for patients with lung cancer have been discussed. The value of ergospirometrial test with maximum oxygen consumption (VO(2peak)) in predicting not only the survival of patients with lung cancer, but also assessing the possibility of pulmonary rehabilitation program...
Source: Pneumonologia i Alergologia Polska - November 3, 2012 Category: Respiratory Medicine Authors: Jastrzębski D, Ziora D, Hydzik G, Pasko E, Bartoszewicz A, Kozielski J, Nowicka J Tags: Pneumonol Alergol Pol Source Type: research

Cardiac tamponade due to rupture of coronary artery fistula to the coronary sinus with giant aneurysm of coronary artery: usefulness of transthoracic echocardiography
Abstract A 68-year-old woman was admitted to our hospital because of back pain and syncope. Transthoracic echocardiography revealed pericardial effusion, a collapsed right ventricle, a giant aneurysm connected to the coronary sinus, a dilated left main trunk coronary artery, and a dilated left circumflex artery (LCx). Furthermore, there was a coronary artery fistula arising from the LCx that drained into the coronary sinus. We diagnosed cardiac tamponade due to rupture of the coronary artery fistula or giant aneurysm, and successful emergency surgery was performed. Rupture of coronary artery aneurysm or coro...
Source: Heart and Vessels - November 2, 2012 Category: Cardiology Tags: Heart and Vessels Source Type: research

Dextro-Transposition of the Great Arteries in a Neonate with Ventricular Septal Defect and Pulmonary Stenosis Complicated by Premature Closure of the Ductus Arteriosus and Possible Pathophysiology of Both Defects
We present a case of a newborn who demonstrated d-TGA with ventricular septal defect (VSD) and pulmonary stenosis (PS) complicated by PCDA. The neonate showed severe cyanosis resistant to resuscitation soon after birth, and was diagnosed with d-TGA with VSD by echocardiography. PPHN was also suspected based on physical symptoms and results of echocardiography. The neonate was given inhaled nitric oxide, prostaglandin E1, and catecholamines under sedation, and underwent a balloon atrial septostomy (BAS). His condition gradually improved, and he was extubated on day 7, but his pulmonary subvalvular stenosis gradually wo...
Source: Pediatric Cardiology - November 2, 2012 Category: Cardiology Tags: Pediatric Cardiology Source Type: research

Physiology, Not Chronology, Dictates Outcomes after Esophagectomy for Esophageal Cancer: Outcomes in Patients 80 Years and Older
Conclusions Elderly patients undergoing esophagectomy are at greater risk of postoperative complications. However, there were no significant differences in other major parameters, including length of hospital stay, mortality, and survival, indicating that selected patients ≥80 years old can and should be assessed by an experienced surgeon. Content Type Journal ArticleCategory Thoracic OncologyPages 1-7DOI 10.1245/s10434-012-2703-xAuthors Sheraz R. Markar, Department of Thoracic Surgery, Virginia Mason Medical Center, Seattle, WA, USADonald E. Low, Department of Thoracic Surgery, Virginia Maso...
Source: Annals of Surgical Oncology - November 2, 2012 Category: Cancer & Oncology Tags: Annals of Surgical Oncology Source Type: research

Benign metastasizing leiomyoma of the lung: report of a case
Abstract A 35-year-old female presented with multiple bilateral pulmonary nodules on a chest X-ray during a regular health checkup. Chest computed tomography revealed multiple well-defined nodular shadows in the lung. She had undergone a myomectomy 7 years previously for leiomyoma of the uterus. Thoracoscopic resection of one of the nodules was performed to establish a pathological diagnosis. Pathological findings were consistent with benign metastasizing leiomyoma. Estrogen and progesterone receptors showed strong positives by immunohistostaining of the tumor. The patient is currently receiving outpati...
Source: General Thoracic and Cardiovascular Surgery - November 2, 2012 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic and Cardiovascular Surgery Source Type: research

The Society of Thoracic Surgeons Isolated Aortic Valve Replacement (AVR) Composite Score: A Report of the STS Quality Measurement Task Force.
CONCLUSIONS: STS has developed a composite mortality and morbidity outcomes measure for isolated AVR to be used in quality assessment, provider feedback, public reporting, and performance improvement. PMID: 23127768 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 2, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Shahian DM, He X, Jacobs JP, Rankin JS, Welke KF, Filardo G, Shewan CM, O'Brien SM Tags: Ann Thorac Surg Source Type: research

Infections by Gram-Negative Bacilli in Patients With Pulmonary Arterial Hypertension Treated with Intravenous Prostacyclin.
PMID: 23127721 [PubMed - as supplied by publisher]
Source: Archivos de Bronconeumologia - November 2, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Gómez Sánchez MA Tags: Arch Bronconeumol Source Type: research

Reduced port laparoscopic repair of Bochdalek hernia in an adult: A first report
This report validates the feasibility of reduced port laparoscopic repair of Bochdalek hernia in an adult, and should be within the remit of the advanced laparoscopic surgeon.
Source: Journal of Minimal Access Surgery - November 2, 2012 Category: Surgery Authors: Pravin Hector JohnJohn ThanakumarArunkumar Krishnan Source Type: research

X-Spine lands FDA approval for two spinal implants
X-spine Systems Inc. has received FDA approval for two spinal implants, advancing the company as a full-line spinal system provider. The Miamisburg-based company, which manufactures spinal implants and instruments for use in spinal surgery, gained federal approval for its Fortex CoCr Rod System and Certex Cervico-thoracic Fixation System. The Fortex CoCr adds strength and functionality to the original Fortex system with a cobalt chromium fixation rod, and the Certex system expands X-spine’s product…
Source: bizjournals.com Health Care:Biotechnology headlines - November 1, 2012 Category: Biotechnology Authors: Laura Englehart Source Type: research

Group Issues New Antiplatelet Guideline (CME/CE)
(MedPage Today) -- With a host of new antiplatelet drugs on the market, the Society of Thoracic Surgeons has updated its clinical practice guideline on the drugs' use during heart surgery.
Source: MedPage Today Surgery - November 1, 2012 Category: Surgery Source Type: news

26th European Association for Cardio-Thoracic Surgery (EACTS) Annual Meeting26th European Association for Cardio-Thoracic Surgery (EACTS) Annual Meeting
Read clinically focused news coverage of key developments from EACTS 2012. Medscape Cardiology
Source: Medscape Today Headlines - November 1, 2012 Category: Consumer Health News Tags: Conference Coverage Source Type: news

Stroke after cardiac surgery – hemispheric distribution and survival
Scandinavian Cardiovascular Journal, Volume 0, Issue 0, Page 1-9, Early Online.
Source: Scandinavian Cardiovascular Journal - November 1, 2012 Category: Cardiology Tags: article Source Type: research

Genome-wide investigation of gene–environment interactions in colorectal cancer
Abstract Colorectal cancer (CRC), one of the most frequent neoplasias worldwide, has both genetic and environmental causes. As yet, however, gene–environment (G × E) interactions in CRC have been studied mostly for a small number of candidate genes only. Therefore, we investigated the possible interaction, in CRC etiology, between single-nucleotide polymorphisms (SNPs) on the one hand, and overweight, smoking and alcohol consumption on the other, at a genome-wide level. To this end, we adopted a two-tiered approach comprising a case-only screening stage I (314 cases) and a case–control validat...
Source: Human Genetics - November 1, 2012 Category: Genetics & Stem Cells Tags: Human Genetics Source Type: research

Synergistic Effect of Bcl-2 and Cyclin A2 on Adverse Recurrence-Free Survival in Stage I Non-small Cell Lung Cancer
Conclusions Negative effect of cyclin A2 on RFS in stage I NSCLC was aggravated by negative expression of Bcl-2. Content Type Journal ArticleCategory Thoracic OncologyPages 1-8DOI 10.1245/s10434-012-2727-2Authors Eunkyung Ko, Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South KoreaYujin Kim, Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South KoreaEun Yoon Cho, Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South KoreaJungho Han, Department of Pathology, Samsung Med...
Source: Annals of Surgical Oncology - November 1, 2012 Category: Cancer & Oncology Tags: Annals of Surgical Oncology Source Type: research

Results of cardiac surgery in advanced liver cirrhosis
Conclusions Although the mortality of redo surgery was high, cardiac surgery could be safely performed in selected patients with advanced liver cirrhosis. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s11748-012-0175-3Authors Naoto Morimoto, Division of Cardiovascular Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, chuo-ku, Kobe, Hyogo 650-0017, JapanKenji Okada, Division of Cardiovascular Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, chuo-ku, Kobe, Hyogo 650-0017, JapanYutaka Okita, Division of Cardiovascular Surgery, ...
Source: General Thoracic and Cardiovascular Surgery - November 1, 2012 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic and Cardiovascular Surgery Source Type: research

There is always hope after PCI and stenting
We report an uncommon and challenging way to achieve a complete off-pump coronary revascularization of a seriously diseased, ‘full metal jacket’ left anterior descending artery (LAD), combining three different techniques at the same time: stent removal, endarterectomy and coronary artery bypass graft (CABG).
Source: Journal of Cardiovascular Medicine - November 1, 2012 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research