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This page shows you the most recent publications within this specialty of the MedWorm directory.

The WHY of SAHM: 45 Years Later
Friends, colleagues, and guests. It is an honor and privilege to stand before you as I assume the 43rd presidency of the Society for Adolescent Health and Medicine (SAHM). I sincerely thank the SAHM membership for bestowing this honor on me. I am excited about the opportunity to work with a fabulous group of people who share my commitment to adolescent health and huge affection for SAHM. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Authors: Debra K. Katzman Tags: Positions of the Society for Adolescent Health and Medicine Source Type: research

Recommended Vitamin D Intake and Management of Low Vitamin D Status in Adolescents: A Position Statement of the Society for Adolescent Health and Medicine
Vitamin D deficiency is common in adolescents worldwide, and the list of reported detrimental health effects associated with this deficiency continues to grow . Even subclinical deficiency during adolescence may affect bone acquisition, potentially reducing peak bone mass and increasing the risk of osteoporosis in later life. Current evidence suggests that giving vitamin D supplements to adolescents who are vitamin D–deficient may improve their bone mineral density as well as increase their total bone mineral content . There is also recent evidence to suggest that an adequate vitamin D intake is associated with decrease...
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Authors: The Society for Adolescent Health and Medicine Tags: Positions of the Society for Adolescent Health and Medicine Source Type: research

Promoting Equity and Reducing Health Disparities Among Racially/Ethnically Diverse Adolescents: A Position Paper of the Society for Adolescent Health and Medicine
The Society for Adolescent Health and Medicine (SAHM) is an international and multidisciplinary organization whose mission is “committed to improving the physical and psychosocial health and well-being of all adolescents through advocacy, clinical care, health promotion, health service delivery, professional development and research.” As a leader in adolescent health, SAHM recognizes the need to specifically address racial/ethnic disparities and inequity that can negatively impact adolescent development, health, and achievement. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Authors: The Society for Adolescent Health and Medicine Tags: Positions of the Society for Adolescent Health and Medicine Source Type: research

Erratum
Bradley BJ, Greene AC. Do Health and Education Agencies in the United States Share Responsibility for Academic Achievement and Health? A Review of 25 Years of Evidence About the Relationship of Adolescents' Academic Achievement and Health Behaviors. J Adolesc Health 2013;52:523–532. http://dx.doi.org/10.1016/j.jadohealth.2013.01.008. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Tags: Errata Source Type: research

Erratum
Identifying Opportunities for Cancer Prevention During Preadolescence and Adolescence. J Adolesc Health 2013;52:5(Suppl). In this supplement to the Journal of Adolescent Health, the subsection title “High-Risk Behaviors” should have appeared as “Behavioral Risks.” This has already been corrected in the issue online. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Tags: Errata Source Type: research

Thanks to Our 2012 Reviewers
Our peer reviewers work tirelessly to ensure the scientific quality and relevance of the manuscripts published in our Journal. They receive little recognition for this service, and their helpful critiques and knowledgeable insights are generally appreciated by only a select few. The editors of the Journal of Adolescent Health would like to take this opportunity to offer our sincere appreciation to those individuals who reviewed manuscripts for us during 2012. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Tags: Thanks to Reviewers Source Type: research

Older Sexual Partners May Contribute to Racial Disparities in HIV Among Young Men Who Have Sex With Men
See Related Article p. 682 (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Authors: Brian Mustanski, Michael E. Newcomb Tags: Editorials Source Type: research

Who Dies? Disparities in Mortality Risk Among Juvenile Offenders
See Related Article p. 689 (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Authors: Todd I. Herrenkohl Tags: Editorials Source Type: research

Assessment of Youth-Friendly Health Care: A Systematic Review of Indicators Drawn From Young People's Perspectives
Conclusion: These eight domains provide a practical framework for assessing how well services are engaging young people. Measures of youth-friendly health care should address universally applicable indicators of youth-friendly care and may benefit from additional questions that are specific to the local health setting. (Source: Journal of Adolescent Health)
Source: Journal of Adolescent Health - May 22, 2013 Category: Child Development Authors: Anne-Emmanuelle Ambresin, Kristina Bennett, George C. Patton, Lena A. Sanci, Susan M. Sawyer Tags: Review Article Source Type: research

Potential Advantages of Using Synchrotron X-ray Based Techniques in Pediatric Research.
Abstract Synchrotron radiation (SR), which combines extremely high intensity, high collimation, tunability, and continuous energy spectrum, allows the development of advanced X-ray based techniques that are becoming a uniquely useful tool in life science research, along providing exciting opportunities in biomedical imaging and radiotherapy. This review summarize emerging techniques and their potential to greatly enhance the exploration of dynamical biological process occurring across various spatial and temporal regimes, from whole body physiology, down to the location of individual chemical species within single ...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Pascolo L, Esteve F, Rizzardi C, James S, Menk RH Tags: Curr Med Chem Source Type: research

MDM2 Non-Genotoxic Inhibitors as Innovative Therapeutic Approaches for the Treatment of Pediatric Malignancies.
Abstract Since the discovery of p53 as "guardian of the genome" , a large number of efforts have been put in place in order to find molecular strategies aiming to restore p53 wild-type functions, particularly in the light of the fact that its pathway results ineffective in most tumors even though they have non-mutated p53. In this context, pediatric cancers, that are mostly p53 wild-type at the time of diagnosis, represent an ideal target for such therapeutic approach. Within the several mechanisms and proteins ruling p53 activity, the murine double minute 2 (MDM2) is its crucial negative regulator, frequently foun...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Tisato V, Norcio A, Voltan R, Celeghini C, Zella D, Secchiero P Tags: Curr Med Chem Source Type: research

Luminescent silica nanoparticles for cancer diagnosis.
Abstract Fluorescence imaging techniques are becoming essential for preclinical investigations, necessitating the development of suitable tools for in vivo measurements. Nanotechnology entered this field to help overcome many of the current technical limitations, and luminescent nanoparticles (NPs) are one of the most promising materials proposed for future diagnostic implementation. NPs also constitute a versatile platform that can allow facile multi-functionalization to perform multimodal imaging or theranostics (simultaneous diagnosis and therapy). In this contribution we have mainly focused on dye doped silica ...
Source: Current Medicinal Chemistry - May 22, 2013 Category: Chemistry Authors: Arap W, Pasqualini R, Montalti M, Petrizza L, Prodi L, Rampazzo E, Zaccheroni N, Marchio S Tags: Curr Med Chem Source Type: research

Modeling mixtures of thyroid gland function disruptors in a vertebrate alternative model, the zebrafish eleutheroembryo.
Abstract Maternal thyroxine (T4) plays an essential role in fetal brain development, and even mild and transitory deficits in free-T4 in pregnant women can produce irreversible neurological effects in their offspring. Women of childbearing age are daily exposed to mixtures of chemicals disrupting the thyroid gland function (TGFDs) through the diet, drinking water, air and pharmaceuticals, which has raised the highest concern for the potential additive or synergic effects on the development of mild hypothyroxinemia during early pregnancy. Recently we demonstrated that zebrafish eleutheroembryos provide a suitable al...
Source: Toxicology and Applied Pharmacology - May 22, 2013 Category: Toxicology Authors: Thienpont B, Barata C, Raldúa D Tags: Toxicol Appl Pharmacol Source Type: research

Early childhood diarrhea and cardiometabolic risk factors in adulthood: the Institute of Nutrition of Central America and Panama Nutritional Supplementation Longitudinal Study.
CONCLUSIONS: Childhood diarrhea burden at 0 to 6 months is associated with MetS in adulthood after controlling for childhood growth parameters and adult BMI. PMID: 23608305 [PubMed - in process] (Source: Annals of Epidemiology)
Source: Annals of Epidemiology - May 22, 2013 Category: Epidemiology Authors: Deboer MD, Chen D, Burt DR, Ramirez-Zea M, Guerrant RL, Stein AD, Martorell R, Luna MA Tags: Ann Epidemiol Source Type: research

Type III Polyglandular Autoimmune Syndromes in children with type 1 diabetes mellitus.
CONCLUSIONS: PAS III occurs in 14.5% of children with DM type1 and the incidence is positively correlated with patients' age and female gender. Children with PAS III should be carefully monitored as a group at risk for the development of other autoimmune diseases. PMID: 23540228 [PubMed - in process] (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - May 22, 2013 Category: Environmental Health Authors: Ben-Skowronek I, Michalczyk A, Piekarski R, Wysocka-Łukasik B, Banecka B Tags: Ann Agric Environ Med Source Type: research

Medical and psychosocial factors conditioning development of stress urinary incontinence (SUI).
CONCLUSIONS: Statistically significant differences were found between the group of patients with SUI and the control group, with respect to the number of deliveries and their duration. The study showed that there is a statistically higher probability of the development of SUI in the case of surgical delivery, or natural childbirth of a baby with a birth weight of 4000 g or more. The study showed that hard physical work and past gynaecological surgeries are risk factors of urinary incontinence. Barriers of a psychosocial nature were also found (feeling of shame and embarrassment accompanying disclosure of the SUI), which mi...
Source: Annals of Agricultural and Environmental Medicine : AAEM - May 22, 2013 Category: Environmental Health Authors: Iwanowicz-Palus GJ, Stadnicka G, Włoszczak-Szubzda A Tags: Ann Agric Environ Med Source Type: research

Systematic analysis of the relationship between standardized prenatal exposure to polychlorinated biphenyls and mental and motor development during follow-up of nine children cohorts.
The objective of this research was to use a procedure previously developed to standardize PCB biological concentration data across cohorts in order to perform a systematic analysis of temporal associations between prenatal PCB exposure and mental and motor development from neonatal period (or a young age) until school age. Prenatal exposure data from nine cohorts were standardized in terms of total PCBs per kg of lipids in maternal plasma. Systematic analysis of the "standardized biological concentration-development" relationship during follow-up of each cohort was then conducted through the application of Hill criteria. T...
Source: Regulatory Toxicology and Pharmacology : RTP - May 22, 2013 Category: Toxicology Authors: El Majidi N, Bouchard M, Carrier G Tags: Regul Toxicol Pharmacol Source Type: research

Bioaccessibility and health risk assessment of arsenic in arsenic-enriched soils, Central India.
Abstract Incidental soil ingestion is expected to be a significant exposure route to arsenic for children because of the potentially high arsenic contents found in certain soils. Therefore, it is prudent to get information on oral bioaccessibility of arsenic following incidental soil ingestion and its relevance in health risk assessment for future remediation strategies. Soil samples were collected from eight villages of Ambagarh Chauki block, Chhattisgarh, Central India. The soils from seven villages had total arsenic content more than the background level of 10mgkg(-1) (ranged from 16 to 417mgkg(-1)), whereas the...
Source: Ecotoxicology and Environmental Safety - May 22, 2013 Category: Environmental Health Authors: Das S, Jean JS, Kar S Tags: Ecotoxicol Environ Saf Source Type: research

How Phenotype and Developmental Stage Affect the Genes We Find: GABRA2 and Impulsivity.
Conclusions: Our results suggest that the pathway by which GABRA2 initially confers risk for eventual alcohol problems begins with a predisposition to sensation-seeking early in adolescence. The findings support the heterogeneous nature of impulsivity and demonstrate that both the measure used to assess a construct of interest and the age of the participants can have profound implications for the detection of genetic associations. PMID: 23561058 [PubMed - in process] (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - May 22, 2013 Category: Genetics & Stem Cells Authors: Dick DM, Aliev F, Latendresse S, Porjesz B, Schuckit M, Rangaswamy M, Hesselbrock V, Edenberg H, Nurnberger J, Agrawal A, Bierut L, Wang J, Bucholz K, Kuperman S, Kramer J Tags: Twin Res Hum Genet Source Type: research

Characteristics of fatal child maltreatment associated with multiple births in Japan.
In conclusion, recent Japanese nationwide data suggests that the non-specific overburden of child rearing might be one possible reason for higher frequency of child maltreatment for multiples compared with singletons, and parental comparisons between two twins might be another. The penal sentences for fatal child maltreatment might be more lenient for perpetrators of this crime against twins than against singletons. PMID: 23632231 [PubMed - in process] (Source: Twin Research and Human Genetics)
Source: Twin Research and Human Genetics - May 22, 2013 Category: Genetics & Stem Cells Authors: Ooki S Tags: Twin Res Hum Genet Source Type: research

Editorial: The challenge of mapping diagnostic categories onto developmental pathophysiology: DSM‐6 anyone?
(Source: Journal of Child Psychology and Psychiatry)
Source: Journal of Child Psychology and Psychiatry - May 22, 2013 Category: Psychiatry Authors: Edmund Sonuga‐Barke Tags: Editorial Source Type: research

Commentary: Filling out the evidence base for treatment of attention‐deficit hyperactivity disorder symptoms in children with intellectual and developmental disability: conclusions for clinicians – a response to Simonoff et al. (2013)
This randomized clinical trial of methylphenidate in children with intellectual disability (ID) by Simonoff et al. (2013) advances the field in several ways useful to clinicians. The three‐figure widely representative sample more definitively confirms findings previously reported from smaller studies and studies with a differently selected sample. The medium placebo‐controlled effect size found is in line with previous more tentative suggestions for ID, such as those summarized by Aman et al. This sample, selected for ID but coincidentally including some children with autism (a third of the sample), nicely complements ...
Source: Journal of Child Psychology and Psychiatry - May 22, 2013 Category: Psychiatry Authors: L. Eugene Arnold Tags: Commentary Source Type: research

Least said, soonest mended?: Responses of primary school teachers to the perceived support needs of bereaved children
This article expands upon research with primary school teachers articulating something of their knowledge and experience in encountering bereaved children. The mixed methodology research includes quantitative and qualitative data that incorporate teachers’ responses to the fictionalised narrative of a bereaved 6-year-old. The discussion elucidates teachers’ confidence – or reluctance – in broaching the topic, highlighting the lack of specific training within teacher education for understanding and supporting bereaved children. Compassionate understanding is offered to some children, but many others ...
Source: Journal of Early Childhood Research - May 22, 2013 Category: Child Development Authors: Potts, S. Tags: Articles Source Type: research

Cultural negotiation: Moving beyond a cycle of misunderstanding in early childhood settings
This study explores communication processes and expectations of continuity of care between home and early childhood setting. A social constructivism approach using qualitative methods of data gathering explored family and educator perceptions of continuity between home and setting. A cycle of misunderstanding is explained that ascribes characteristics of possible family educators’ responses as a result of a poor understanding between roles. The discussion draws together the need to ascertain processes for negotiating with families and exploring practices that support the building of partnerships between families from...
Source: Journal of Early Childhood Research - May 22, 2013 Category: Child Development Authors: De Gioia, K. Tags: Articles Source Type: research

Working with gender pedagogics at 14 Swedish preschools
In Sweden, gender pedagogics has been on the political agenda the last decade. Consequently, gender matters have been given much attention in Swedish preschools, and specialized pedagogues have also been trained to counteract socially constructed gender distinctions. Therefore, we have explored the enactment of gender pedagogics. We asked 17 preschool teachers to describe the situations revolving around gender issues that they have experienced, using the critical incident method. In all, 34 critical incidents were described and subsequently discussed in groups of 6–10 individuals. Afterward, the data were analyzed qu...
Source: Journal of Early Childhood Research - May 22, 2013 Category: Child Development Authors: Sandstrom, M., Stier, J., Sandberg, A. Tags: Articles Source Type: research

Canadian parents' knowledge and satisfaction regarding their child's day-care experience
The purpose of this study was to examine parental selection criteria and satisfaction with day care, knowledge about centre philosophy, teacher education and quality of the day-care environment. Parents (n = 261) and educators (n = 94) in 44 non-profit centres in three Canadian cities participated. Parent knowledge was assessed by phone interview, and day-care quality was rated. Many parents reported knowledge of the centre’s philosophy and were highly satisfied with the care but sometimes held inaccurate views of the teacher’s education. Parent education positively predicted parental knowledge of centre philos...
Source: Journal of Early Childhood Research - May 22, 2013 Category: Child Development Authors: Howe, N., Jacobs, E., Vukelich, G., Recchia, H. Tags: Articles Source Type: research

Young children engaging with technologies at home: The influence of family context
This article is about the ways in which young children engage with technological toys and resources at home and, in particular, the ways in which the family context makes a difference to young children’s engagement with these technologies. The data reviewed come from family interviews and parent-recorded video of four case study children as they used specific resources: a screen-based games console designed for family use, a technology-mediated reading scheme, a child’s games console and two technological ‘pets’. We found the same repertoire of direct pedagogical actions across the families when the...
Source: Journal of Early Childhood Research - May 22, 2013 Category: Child Development Authors: Stephen, C., Stevenson, O., Adey, C. Tags: Articles Source Type: research

Relationships between the timing of social interactions and preschoolers' engagement in preschool classrooms
Social factors in the classroom (such as interactions with peers and teachers, talk, observation of others, and presence of peers and teachers) influence engagement, but little is known about the sequence or timing of these social factors with engagement. In this observational study of 12 preschoolers, ages 2–5 years, the influence of the timing of social factors on engagement was examined in depth, using sequential analysis techniques. Children’s talk to teachers and teacher presence encouraged initial engagement in activities. Teacher and peer presence, talk to and from peers, and self-talk encouraged continu...
Source: Journal of Early Childhood Research - May 22, 2013 Category: Child Development Authors: Test, J. E., Cornelius-White, J. H. D. Tags: Articles Source Type: research

Understanding influences of play on second language learning: A microethnographic view in one Head Start preschool classroom
This study demonstrates how play among preschool-aged children can foster English language learning. Using an ethnographic approach, one classroom composed of two teachers and 17 four- to five-year-old children was observed and videotaped during Free Play. Interactional analyses of four Spanish-speaking children’s play scenarios with their same-language peers and English-speaking peers illustrate how through these social interactions their oral English language was supported and, at times, hindered. The implications for play as an avenue for supporting English language learning in the classroom are discussed. (Source...
Source: Journal of Early Childhood Research - May 22, 2013 Category: Child Development Authors: Piker, R. A. Tags: Articles Source Type: research

Association between risk indicators for child development and maternal emotional state
OBJETIVO: analisar a associação entre os estados emocionais maternos depressivo e ansioso, combinados ou de modo isolado, em relação à presença de risco ao desenvolvimento infantil na faixa etária de 0 a 4 meses. MÉTODO: trata-se de estudo observacional, analítico e de coorte. Para a obtenção dos dados foram utilizados os Inventários de Beck de Depressão e de Ansiedade e analisada a interação mãe-bebê a partir do protocolo de índices de risco ao desenvolvimento infantil em uma amostra de 182 díades. RESULTADOS: o percentual de bebês com pelo menos um índice de risco no grupo de mães que apresentaram d...
Source: Revista CEFAC - May 21, 2013 Category: Speech Therapy Source Type: research

Evaluation of infants in follow up program based on the family's perspective
CONCLUSION: we analyzed the quality of the current health management model and suggest it be continued. However, it should start during gestation, include a higher number of follow up consultations and develop more multidisciplinary work. (Source: Revista CEFAC)
Source: Revista CEFAC - May 21, 2013 Category: Speech Therapy Source Type: research

Profile of children attended in the speech therapy department of the high risk children clinic in Franca/SP
CONCLUSION: the data obtained in this study point to the effectiveness of speech therapy intervention in the early stimulation of sucking in newborn pre-term, in relation to the global baby development. Early stimulation of speech therapy in newborn preterm infants is critical for an adequate and nutritious feeding. (Source: Revista CEFAC)
Source: Revista CEFAC - May 21, 2013 Category: Speech Therapy Source Type: research

Relationship between time and type of breastfeeding and stomatognathic system functions
CONCLUSION: it was possible to conclude that, generally, there was no significant relation between time and type of feeding and the investigated functions, except for the significance between type of feeding and chewing. Probably, the lack of significance is due to the fact that the development of all the stomatognathic system has multifactorial sources. The statistical significance found as for the chewing function, since it showed an unexpected pattern, may have occurred because of the restricted number of subjects in each subgroup. (Source: Revista CEFAC)
Source: Revista CEFAC - May 21, 2013 Category: Speech Therapy Source Type: research

Acoustic characteristics of glottal stop associated to Pierre Robin Sequence: case study
A fissura de palato, em associação à Sequência de Pierre Robin, pode favorecer o desenvolvimento de produções atípicas (compensatórias), na fala da criança, como é o caso da oclusiva glotal (golpe de glote) comumente observada em substituição aos sons oclusivos (vozeados ou não). No presente estudo, foi realizada a análise dos parâmetros fonético-acústicos da oclusiva glotal produzidas em /k/ e /g/ por uma criança do gênero feminino, com 5 anos, que apresentava fissura de palato reparada, associada à Sequência de Pierre Robin. Para isso, foram selecionadas seis palavras em que a oclusiva velar encontra...
Source: Revista CEFAC - May 21, 2013 Category: Speech Therapy Source Type: research

Early relationships and marriage in conflict and post-conflict settings: vulnerability of youth in Uganda
This article presents factors which contribute to early relationships and informal marriages in conflict and post-conflict settings, based on qualitative research undertaken among two distinct populations in Uganda: internally displaced persons in Mucwini transit camp in northern Uganda and Congolese refugees in the Nakivale refugee settlement in southwestern Uganda. Themes were examined through a social–ecological framework. Findings indicate that fundamental shifts in economies, family relationships, and communication combined with structural changes encountered in settlements resulted in changed relationships and marr...
Source: Reproductive Health Matters - May 20, 2013 Category: Global & Universal Authors: Jennifer Schlecht, Elizabeth Rowley, Juliet Babirye Source Type: research

Meeting the commitments of the ICPD Programme of Action to young people
Abstract: Some of the commitments nations have made in international agreements, notably in the ICPD Programme of Action (1994) and the resolution of the UN Committee on Population & Development (2012), to young people include: realisation of the right to education and attainment of a secondary school education; delaying marriage beyond childhood and ensuring free and full choice in marriage-related decisions; exercise of the right to health, including access to friendly health services and counselling; access to health-promoting information, including on sexual and reproductive matters; acquisition of protective assets an...
Source: Reproductive Health Matters - May 20, 2013 Category: Global & Universal Authors: Shireen J Jejeebhoy, AJ Francis Zavier, KG Santhya Source Type: research

Cost Savings Associated with Prohibiting Smoking in U.S. Subsidized Housing
Conclusions: Efforts to prohibit smoking in all U.S. subsidized housing would protect health and generate substantial cost savings to society. (Source: American Journal of Preventive Medicine)
Source: American Journal of Preventive Medicine - May 20, 2013 Category: Global & Universal Authors: Brian A. King, Richard M. Peck, Stephen D. Babb Tags: Brief Reports Source Type: research

The Prevalence of 16p12.1 Microdeletion in Patients with Left‐sided Cardiac Lesions
ConclusionIn our cohort, structural variation at 16p12.1 was not identified with increased frequency in patients with left‐sided lesions as compared with controls. (Source: Congenital Heart Disease)
Source: Congenital Heart Disease - May 20, 2013 Category: Cardiology Authors: Lisa C.A. D'Alessandro, Petra Werner, Hongbo M. Xie, Hakon Hakonarson, Peter S. White, Elizabeth Goldmuntz Tags: Original Article Source Type: research

Abiotrophia Endocarditis in Children with No Underlying Heart Disease: A Rare but a Virulent Organism
We report two cases of Abiotrophia infective endocarditis in children without any predisposing factors. Both patients presented with nonspecific symptoms leading to delay in diagnosis. While bacteriological clearance was achieved in both cases, both had a complicated course including development of brain mycotic aneurysms, splenic infarction, renal failure, and irreversible damage to the mitral valve. Both patients required surgical removal of the native mitral valve and replacement. We also present review of seven cases with similar diagnosis published previously in literature and highlight important differences. Our case...
Source: Congenital Heart Disease - May 20, 2013 Category: Cardiology Authors: Deepti P. Bhat, Lakshmi Nagaraju, Basim I. Asmar, Sanjeev Aggarwal Tags: Case Report Source Type: research

Reducing residual risk: modern pharmacochemistry meets old-fashioned lifestyle and adherence improvement
Despite remarkable advances in identifying and managing coronary heart disease, the global burden of cardiovascular (CV) risk and levels of undetected, subclinical heart disease remain enormous. Substantial numbers of patients do not reach their therapeutic goals, others are unable to tolerate the treatments, half may fail to adhere to their programs, and in those who do attain their targets, major cardiovascular events may continue. Well-known risk factors, such as obesity and diabetes, have now gained the upper hand, with no evidence-based remedy capable of reversing this trend. All told, less than 1% of American adults ...
Source: Therapeutic Advances in Cardiovascular Disease - May 20, 2013 Category: Cardiology Authors: Kones, R. Tags: Reviews Source Type: research

An Exploration of Imitation Recognition in Young Children With Autism Spectrum Disorders
This study compared the degree to which children with ASD engage in different behaviors thought to be indicative of IR during a naturalistic imitation task and the relationship between different types of IR behaviors and social‐cognitive skills (i.e. imitation, language, social reciprocity, and joint attention). Thirty children with ASD were administered standardized measures of cognitive level, language, joint attention, social reciprocity, and imitation. IR behaviors were observed during periods of contingent imitation by an adult. Participants engaged more frequently in less mature (e.g. looking at the experimenter's ...
Source: Autism Research - May 20, 2013 Category: Psychiatry Authors: Natalie I. Berger, Brooke Ingersoll Tags: Short Report Source Type: research

Social Attention in a Virtual Public Speaking Task in Higher Functioning Children With Autism
In this study, a public speaking task was used to study social attention, its moderators, and its association with classroom learning in elementary and secondary students with higher functioning autism spectrum disorder (HFASD). Thirty‐seven students with HFASD and 54 age‐ and intelligence quotient (IQ)‐matched peers without symptoms of ASD were assessed in a virtual classroom public speaking paradigm. This paradigm assessed the ability to attend to nine avatar peers seated at a table, while simultaneously answering self‐referenced questions. Students with HFASD looked less frequently to avatar peers in the classro...
Source: Autism Research - May 20, 2013 Category: Psychiatry Authors: William Jarrold, Peter Mundy, Mary Gwaltney, Jeremy Bailenson, Naomi Hatt, Nancy McIntyre, Kwanguk Kim, Marjorie Solomon, Stephanie Novotny, Lindsay Swain Tags: Research Article Source Type: research

Is it a boy or a girl? Who should (not) know children's sex and why?
In this paper, we present the case of a couple who refused to disclose the sex of their child to others, and some of the responses that this case prompted in the international media. We outline the ethical issues that this case raises, and we place it into the more general context of parental preferences regarding the gender (development) of their children and of the impact on children of parental choices in the matter. Based on current knowledge of gender identity development, we identify some of the potential pitfalls of such a course of action and we briefly present some alternative strategies that could be implemented ...
Source: Journal of Medical Ethics - May 19, 2013 Category: Medical Ethics Authors: Cutas, D. E., Giordano, S. Tags: Psychology and medicine Current controversy Source Type: research

The effect of preimplantation genetic screening on neurological, cognitive and behavioural development in 4-year-old children: follow-up of a RCT
STUDY QUESTION Does embryo biopsy inherent to preimplantation genetic screening (PGS) affect neurological, cognitive and behavioural development of 4-year-old children? SUMMARY ANSWER PGS does not seem to affect neurological, cognitive and behavioural development of 4-year-old singletons; however, our data suggest that it may be associated with altered neurodevelopment in twins. WHAT IS KNOWN ALREADY Evidence concerning the safety of PGS on neurodevelopmental outcome in offspring is scarce. The present study provides information on neurodevelopmental, cognitive and behavioural outcome of 4-year-old PGS offspring. STUDY ...
Source: Human Reproduction - May 18, 2013 Category: Reproduction Medicine Authors: Schendelaar, P., Middelburg, K. J., Bos, A. F., Heineman, M. J., Kok, J. H., La Bastide-Van Gemert, S., Seggers, J., Van den Heuvel, E. R., Hadders-Algra, M. Tags: Embryology Source Type: research

The influence of sporadic anovulation on hormone levels in ovulatory cycles
STUDY QUESTION Do ovulatory hormone profiles among healthy premenopausal women differ between women with and without sporadic anovulation? SUMMARY ANSWER Women with one anovulatory cycle tended to have lower estradiol, progesterone and LH peak levels during their ovulatory cycle. WHAT IS KNOWN ALREADY Anovulation occurs sporadically in healthy premenopausal women, but the influence of hormones in a preceding cycle and the impact on a subsequent cycle's hormone levels is unknown. STUDY DESIGN, SIZE, DURATION The BioCycle Study was a prospective cohort including 250 healthy regularly menstruating women, 18–44 years ...
Source: Human Reproduction - May 18, 2013 Category: Reproduction Medicine Authors: Hambridge, H. L., Mumford, S. L., Mattison, D. R., Ye, A., Pollack, A. Z., Bloom, M. S., Mendola, P., Lynch, K. L., Wactawski-Wende, J., Schisterman, E. F. Tags: Reproductive epidemiology Source Type: research

Sleep Disturbance in Pediatric PTSD: Current Findings and Future Directions
Many studies have provided strong evidence of a fundamental and complex role for sleep disturbances in adult posttraumatic stress disorder (PTSD). Investigations of adult PTSD using subjective and objective measures document sleep architecture abnormalities and high prevalence of sleep disordered breathing, periodic limb movement disorder, nightmares, and insomnia. PTSD treatment methods do appear to significantly improve sleep disturbance, and also studies suggest that treatments for sleep disorders often result in improvements in PTSD symptoms. Further, the most recent evidence suggests sleep abnormalities may precede th...
Source: Journal of Clinical Sleep Medicine : JCSM - May 17, 2013 Category: Sleep Medicine Source Type: research

Neonatal mortality in Ethiopia: trends and determinants
Conclusions: Neonatal mortality must decline more rapidly to achieve the Millennium Development Goal (MDG) 4 target for under-5 mortality in Ethiopia. Strategies to address neonatal survival require a multifaceted approach that encompasses health-related and other measures. Addressing short birth interval and preventing early pregnancy must be considered as interventions. Programs must improve the coverage of TTI and prevention of hypothermia for winter births should be given greater emphasis. Strategies to improve neonatal survival must address inequalities in neonatal mortality by women's education and region. (Source: B...
Source: BMC Public Health - Latest articles - May 17, 2013 Category: Consumer Health News Authors: Yared MekonnenBiruk TensouDaniel TelakeTedbabe DegefieAbeba Bekele Source Type: research

Future of Clinical Genomics in Pediatric Oncology [REVIEW ARTICLES]
The somatic genomic alterations in pediatric cancers to some extent overlap with those seen in adult cancers, but the exact distribution throughout the genome and the types and frequency of alterations differ. The ultimate goal of genomic research in children, as with adults, is translation to the clinic to achieve more accurate diagnosis, more precise risk stratification, and more effective, less toxic therapy. The genomic features of pediatric malignancies and pediatric-specific issues in clinical investigation may make translating genomic discoveries to the clinic more difficult. However, through large-scale molecular p...
Source: Journal of Clinical Oncology - May 17, 2013 Category: Cancer & Oncology Authors: Janeway, Place, Kieran, Harris Tags: Developmental Therapeutics & Pharmacology REVIEW ARTICLES Source Type: research