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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.

Shoyogan improves dietary intake in severely anorexic patients with malignant or non‐malignant disease
ConclusionsAlthough the active component(s) of shoyogan have not been identified, this Kampo medicine may be useful in the care of aged and terminally ill patients. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 29, 2015 Category: Complementary Medicine Authors: Takashi Ito, Yoko Kimura, Shizuka Shimamura, Shohaku Yamamoto, Haruhiko Aoyagi, Tomoaki Ozawa, Norio Suda Tags: SHORT COMMUNICATION Source Type: research

Traumatic lateral abdominal wall hematoma treated with Kampo medicines
Conclusion JDI can be used for the management of pain and swelling following abdominal wall hematoma as an alternative to non‐steroidal anti‐inflammatory drugs. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 29, 2015 Category: Complementary Medicine Authors: Hajime Nakae, Manabu Okuyama, Toshiko Igarashi Tags: CASE REPORT Source Type: research

Kamikihito ameliorates tumor‐induced sickness behavior in mice
Conclusion KKT may ameliorate emotional aspects of sickness behavior similarly to or better than milnacipran, and is a potential treatment for sickness behavior. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 29, 2015 Category: Complementary Medicine Authors: Ryota Araki, Shoji Nishida, Yosuke Hiraki, Takeshi Yabe Tags: SHORT COMMUNICATION Source Type: research

Some over-the-counter drugs may be linked to falls in older men
Conclusion This relatively large cohort study found an association between taking medicines with definite anticholinergic activity and an increased risk of injury-causing falls in older men, but not women. The fact that data was collected prospectively is one of this study's strengths, as is the fact that interviewers checked medicine packages to confirm self-reported medication use and could check prescription medication records for some patients. However, this study did have some limitations: Medication use was only assessed at the start of the study and may have changed after this. Falls were self-reported. Parti...
Source: NHS News Feed - July 29, 2015 Category: Consumer Health News Tags: Medication Older people Source Type: news

Retrospective study using MRI to measure depths of acupuncture points in neck and shoulder region
Conclusions Participants with higher BMI had greater measured depths and males tended to have greater depths in most of the points. Clinical practitioners are recommended to consider this information to prevent complications when applying acupuncture treatment to their patients. (Source: BMJ Open)
Source: BMJ Open - July 29, 2015 Category: Journals (General) Authors: Chou, P.-C., Huang, Y.-C., Hsueh, C.-J., Lin, J.-G., Chu, H.-Y. Tags: Open access, Complementary medicine, Evidence based practice, Radiology and imaging Research Source Type: research

B-vitamin status and bone mineral density and risk of lumbar osteoporosis in older females in the United States.
CONCLUSION: In this nationally representative population of older US women with high exposure to B vitamins through food fortification and dietary supplements, only elevated tHcy and MMA were independently associated with risk of lumbar spine osteoporosis. PMID: 26224297 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 29, 2015 Category: Nutrition Authors: Bailey RL, Looker AC, Lu Z, Fan R, Eicher-Miller HA, Fakhouri TH, Gahche JJ, Weaver CM, Mills JL Tags: Am J Clin Nutr Source Type: research

The Dangerous Mix of Adolescents and Dietary Supplements for Weight Loss and Muscle Building: Legal Strategies for State Action
This article reviews studies reporting on Americans' use of dietary supplements marketed for weight loss or muscle building, notes the particular dangers these products pose to the youth, and suggests that states can build on their historical enactment of regulatory controls for products with potential health consequences to protect the public and especially young people from unsafe and mislabeled dietary supplements. (Source: Journal of Public Health Management and Practice)
Source: Journal of Public Health Management and Practice - July 28, 2015 Category: Health Management Tags: Original Articles Source Type: research

Controversial Oxygen Therapy ZAPS Cancer
Get more oxygen into your blood, and it instantly destroys infections, bacteria, fungi, and viruses. Oxygen can even destroy cancer cells without harming healthy cells. In today’s world, getting oxygen to your cells is not as easy as it used to be. Even simple nutritional deficiencies like a lack of omega-3s can prevent oxygen from reaching your cells. When my new wellness center opens in October, I’m introducing several new oxygen therapies including an overlooked yet powerful technology called ozone therapy. But ozone is controversial. It attracts attention from the Feds because it WORKS. And anything that ki...
Source: Al Sears, MD Natural Remedies - July 28, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Source Type: news

Sharing Telomere Secrets At Rome Conference
I left for Rome last week. I went to a conference on “tissue science and regenerative medicine.” I’m giving a lecture on telomeres and I’m presenting results from the latest study of my own patients. For many of the doctors, it will be the first time they’ve heard anything about telomeres. In fact, you probably know more about telomeres than they do. It’s exciting for me to be able to share this new technology with fellow doctors, and today I want to give you a sneak peek at the stunning results I’m presenting during my lecture. You see, I’ve been tracking the progress of my ...
Source: Al Sears, MD Natural Remedies - July 28, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Anti-Aging Source Type: news

Anti-inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn's Disease Associated with Downregulation of NF-κB Signaling
Conclusions: GAC1 inhibited production of TNF-α and other proinflammatory cytokines by PBMCs and inflamed CD colonic mucosa due to blockage of NF-κB activation. GAC1 is a key beneficial constituent in G. lucidum and the Food Allergy Herbal Formula-2 in suppressing the inflammatory cytokines found in CD and warrants clinical investigation for the treatment of CD. (Source: Inflammatory Bowel Diseases)
Source: Inflammatory Bowel Diseases - July 28, 2015 Category: Gastroenterology Tags: Original Basic Science Articles Source Type: research

Use of Intravenous Immunoglobulin for Patients with Inflammatory Bowel Disease with Contraindications or Who Are Unresponsive to Conventional Treatments
Background: Managing patients with IBD who are refractory or have contraindications to standard therapies is challenging. Many will lose response, become intolerant to treatment, or develop infections with contraindication for immunosuppression. Therefore, alternative therapies, such as the use of intravenous immunoglobulin (IVIg), could be used to manage patients in these difficult cases. Methods: Data were extracted retrospectively from the electronic medical records at Vanderbilt University on patients with IBD who received IVIg (February 2011–June 2013). Patients were treated with IVIg 0.4 g·kg−1·d−1 for 3 cons...
Source: Inflammatory Bowel Diseases - July 28, 2015 Category: Gastroenterology Tags: Original Clinical Articles Source Type: research

Adverse Drug Reactions to Self‐Medication: a study in a pharmacovigilance database
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - July 28, 2015 Category: Drugs & Pharmacology Authors: Aurélia Berreni, François Montastruc, Emmanuelle Bondon‐Guitton, Vanessa Rousseau, Delphine Abadie, Geneviève Durrieu, Leyla Chebane, Jean‐Paul Giroud, Haleh Bagheri, Jean‐Louis Montastruc Tags: Short Communication Source Type: research

Psyclones: a roller coaster of life? Hidden synthetic cannabinoids and stimulants in apparently harmless products
ConclusionsBeing sold as a legal product, Psyclone may appeal to recreational users, who remain unaware of its real content. This is a serious public health threat, which may lead to acute intoxications and fatalities. Further studies in the field, including Internet monitoring, are therefore required. Copyright © 2015 John Wiley & Sons, Ltd. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - July 28, 2015 Category: Psychiatry Authors: Rita Santacroce, Ornella Corazza, Giovanni Martinotti, Francesco Saverio Bersani, Giuseppe Valeriani, Massimo Di Giannantonio Tags: Special Issue on Novel Psychoactive Substances Source Type: research

Medicinal plants sold in the markets of Antananarivo, Madagascar
Conclusions: The markets of Antananarivo have always played a vital cultural role in the lives of urban Malagasy, but our study shows they also play an economic role not only for urban residents but rural harvesters as well. Continued research and monitoring of the non-timber forest products trade in Antananarivo is needed to better understand the impact of trade on the wild plant populations. (Source: Journal of Ethnobiology and Ethnomedicine)
Source: Journal of Ethnobiology and Ethnomedicine - July 28, 2015 Category: Complementary Medicine Authors: Maria RandriamiharisoaAlyse KuhlmanVololoniaina JeannodaHarison RabarisonNivo RakotoariveloTabita RandrianarivonyFortunat RaktoarivonyArmand RandrianasoloRainer Bussmann Source Type: research

Confessions of a manufacturer: or, the dream of alchemy
Publication date: Available online 8 July 2015 Source:Journal of Herbal Medicine Author(s): Paul Chenery (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - July 28, 2015 Category: Complementary Medicine Source Type: research

The body in balance: Humoral medicines in practice
Publication date: June 2015 Source:Journal of Herbal Medicine, Volume 5, Issue 2 Author(s): Graeme Tobyn (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - July 28, 2015 Category: Complementary Medicine Source Type: research

Insight into the molecular mechanism of a herbal injection by integrating network pharmacology and in vitro
Publication date: 15 September 2015 Source:Journal of Ethnopharmacology, Volume 173 Author(s): Yi-min Ma, Xin-zhuang Zhang, Zhen-zhen Su, Na Li, Liang Cao, Gang Ding, Zhen-zhong Wang, Wei Xiao Chinese medical herbs could treat complex diseases through the synergistic effect of multi-components, multi-targets and multi-channels. However, it was difficult to systematically investigate the pharmacological mechanisms of action due to the complex chemical composition and the lack of an effective research approach. Fortunately, network pharmacology as an integrated approach was proposed to systematically investigate an...
Source: Journal of Ethnopharmacology - July 28, 2015 Category: Drugs & Pharmacology Source Type: research

Ethnobotanical survey of medicinal plants in Bozyazı district of Mersin, Turkey
Conclusion Throughout the research carried out Bozyazı district, it has been observed that people living in rural areas have more knowledge and experience about the use and benefits of plants, compared to the people living in the district center. It was detected that the medicinal plants have been used mostly in the therapy of Hemorrhoids. The most information is obtained from the mountain villagers and Yuruk nomads, having average ages of 46.3, during the whole study. In terms of ethnobotanical perspective, the district has stayed valuable due to the winding roads over the mountains and along the coast is very difficult ...
Source: Journal of Ethnopharmacology - July 28, 2015 Category: Drugs & Pharmacology Source Type: research

Gastro-protective and Anti-stress Efficacies of Monomethyl Fumarate and a Fumaria indica Extract in Chronically Stressed Rats.
Abstract Results of the very first experiments conducted to evaluate therapeutic potentials of a fumarate containing Fumaria indica extract and of fairly low daily oral doses of monomethyl fumarate for prevention of chronic unavoidable foot-shock stress-induced gastric ulcers, and possible involvement of diverse neuro-hormonal and oxidative process in their stress response desensitizing effects are reported and discussed in this article. Preventive effects of 21 daily oral 60, 120, and 240 mg/kg doses of a standardized 50 % methanolic F. indica extract (MFI) and 1.25, 2.50, and 5.00 mg/kg/day of pure monomethyl ...
Source: Cellular and Molecular Neurobiology - July 28, 2015 Category: Cytology Authors: Shakya A, Soni UK, Rai G, Chatterjee SS, Kumar V Tags: Cell Mol Neurobiol Source Type: research

A sham-controlled trial of acupressure on the quality of sleep and life in haemodialysis patients.
CONCLUSIONS: Acupressure seems to have a positive effect on the sleep quality in haemodialysis patients. CLINICAL TRIAL REGISTRATION: IRCT201106145864N2. PMID: 26215770 [PubMed - as supplied by publisher] (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - July 27, 2015 Category: Complementary Medicine Authors: Arab Z, Shariati AR, Asayesh H, Vakili MA, Bahrami-Taghanaki H, Azizi H Tags: Acupunct Med Source Type: research

Acupuncture for chronic fatigue syndrome and idiopathic chronic fatigue: a multicenter, nonblinded, randomized controlled trial
Background: The causes of chronic fatigue syndrome (CFS) and idiopathic chronic fatigue (ICF) are not clearly known, and there are no definitive treatments for them. Therefore, patients with CFS and ICF are interested in Oriental medicine or complementary and alternative medicine. For this reason, the effectiveness of complementary and alternative treatments should be verified. We investigated the effectiveness of two forms of acupuncture added to usual care for CFS and ICF compared to usual care alone. Methods: A three-arm parallel, non-blinded, randomized controlled trial was performed in four hospitals. We divided 150 p...
Source: Trials - July 26, 2015 Category: Journals (General) Authors: Jung-Eun KimByung-Kwan SeoJin-Bong ChoiHyeong-Jun KimTae-Hun KimMin-Hee LeeKyung-Won KangJoo-Hee KimKyung-Min ShinSeunghoon LeeSo-Young JungAe-Ran KimMi-Suk ShinHee-Jung JungHyo-Ju ParkSung-Phil KimYong-Hyeon BaekKwon-Eui HongSun-Mi Choi Source Type: research

Is There a Role for Homeopathy in Cancer Care? Questions and Challenges
Abstract Patients with cancer commonly use complementary and integrative medicine, including homeopathy. Homeopathy has grown in popularity with the public but is viewed with skepticism by medical academia and is still excluded from conventionally prescribed treatments. In recent years, homeopathy has been used in cancer care in Europe and other countries worldwide. This use raised the question if there is any benefit in utilizing this type of care with cancer patients. The purpose of this manuscript is to explore the evidence related to the benefit of homeopathy in cancer care. Limited research has suggested tha...
Source: Current Oncology Reports - July 26, 2015 Category: Cancer & Oncology Source Type: research

Effects of Electroacupuncture on Pro-/Anti-inflammatory Adipokines in Serum and Adipose Tissue in Lean and Diet-induced Obese Rats
Publication date: Available online 2 July 2015 Source:Journal of Acupuncture and Meridian Studies Author(s): Jacqueline J.T. Liaw, Philip V. Peplow The effects of electroacupuncture (EA) on pro-/anti-inflammatory cytokines and blood glucose (BG) in lean and obese Long Evans rats were investigated. Group 1 and Group 3 had five lean and seven obese rats, respectively, and received EA at the Zhongwan/Guanyuan acupoints on Day 1, Day 3, Day 5, Day 8, Day 10, and Day 12. Group 2 and Group 4, with five lean and seven obese rats, respectively, did not undergo EA. After induction of anesthesia, BG was measured at 10 minutes an...
Source: Journal of Acupuncture and Meridian Studies - July 26, 2015 Category: Complementary Medicine Source Type: research

The endemic medicinal plants of Northern Balochistan, Pakistan and their uses in traditional medicine
Conclusions The Balochistan is rich in endemic and other medicinal plants, still needs more exploration and study. Thus, it is important to document and reconstitute the remainders of the ancient medical practices which exist in Balochistan and other areas of the world, and preserve this knowledge for future generations. The endemic species which are used in traditional medicine in the region lacks phototherapeutic evidence. It is necessary to perform phytochemical or pharmacological studies to explore the potential of plants used for medicinal purposes. Overgrazing, urbanization and unsustainable harvesting of such rare a...
Source: Journal of Ethnopharmacology - July 26, 2015 Category: Drugs & Pharmacology Source Type: research

Prescription patterns of Chinese herbal products for patients with fractures in Taiwan: A nationwide population-based study
Conclusions Our study identified the TCM utilization for patients with fractures in Taiwan. Integration of TCM treatment reduced the medical costs for hospitalization. Further basic research and clinical studies to investigate the mechanism and clinical efficacies of CHPs are warranted. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - July 26, 2015 Category: Drugs & Pharmacology Source Type: research

Ethnopharmacological analysis of medicinal plants used against non-communicable diseases in Rodrigues Island, Indian Ocean
Conclusion Given the dearth of updated information on traditional medicine of Rodrigues, this study can provide an opportunity to establish valuable primary information on the different MP used by the local people and hence can open new perspectives for further pharmacological research. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - July 26, 2015 Category: Drugs & Pharmacology Source Type: research

Zyflamend, a polyherbal mixture, inhibits lipogenesis and mTORC1 signalling via activation of AMPK
The objective in this study was to determine if the antiproliferative effects are mediated, in part, through the activation of AMPK signalling and inhibition of its downstream targets, lipogenesis and mTORC1 complex. By increasing the phosphorylation of AMPK in CWR22Rv1 and PC3 prostate cancer cell lines, Zyflamend decreased de novo lipid biosynthesis by decreasing the activity of acetyl-CoA carboxylase and the expressions of fatty acid synthase and SREBP-1c, with a concomitant up regulation of fatty acid oxidation. In addition, via AMPK, Zyflamend inhibited the activity of mTORC1 complex by directly phosphorylating raptor...
Source: Journal of Functional Foods - July 25, 2015 Category: Nutrition Source Type: research

Therapeutic effect of polysaccharide fraction of Atractylodis macrocephalae Koidz. in bovine subclinical mastitis
Conclusions: Subcutaneous injection of RAMP-O in the area of supramammary lymph node had therapeutic value in the treatment of bovine subclinical mastitis by reducing SCC, NAGase and IMIs in milk. Considering both the therapeutic effect and the cost of RAMP-O, 32 mg per dose was found most suitable to reduce milk SCC and NAGase. Therefore, RAMP-O deserves further study for its use in treatment of bovine mastitis. (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - July 25, 2015 Category: Veterinary Research Authors: Wei XuRan GuanYisong LuXiaoyan SuYe XuAifang DuSonghua Hu Source Type: research

Cissampelos sympodialis Eichl. (Menispermaceae), a medicinal plant, presents antimotility and antidiarrheal activity in vivo
Conclusions: The antidiarrheal activity of C. sympodialis can be attributed to the chemical compounds already isolated and quantified in this species, mainly alkaloids. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 25, 2015 Category: Complementary Medicine Authors: Igor de SalesFlavia MachadoAlexsandro MarinhoAna LúcioJosé FilhoLeônia Batista Source Type: research

Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate induced hepatotoxicity in male albino rat
Conclusions: This study recommends that the co-administration of MUL with MTX that may have therapeutic benefits against MTX-hepato-cytotoxicity. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 25, 2015 Category: Complementary Medicine Authors: Hend Tag Source Type: research

Antioxidant activity and hepatoprotective potential of Cedrelopsis grevei on cypermethrin induced oxidative stress and liver damage in male mice
Background: The liver is the most sensitive and main target organ of pesticide toxicity and damage, they play an essential role in metabolism and detoxification of pesticides. Due to these functions, hepatotoxicity continues to be among the main threats to public health, and they remain problems throughout the world. Therefore, the present study was designed to evaluate the antioxidant and hepatoprotective effects of Cedrelopsis grevei leaves against cypermethrin (Cyp) induced oxidative stress and liver damage in male mice. Methods: The extracts were subjected to different analyses (phenolics, tannin, flavonoids, antioxida...
Source: BMC Complementary and Alternative Medicine - July 25, 2015 Category: Complementary Medicine Authors: Abdel-Tawab MossaTarek HeikalMeriam BelaibaEmmanuel RaoelisonHicham FerhoutJalloul Bouajila Source Type: research

Crude triterpenoid saponins from Anemone flaccida (Di Wu) exert anti-arthritic effects on type II collagen-induced arthritis in rats
This study aims to evaluate the underlying action mechanism of A. flaccida crude triterpenoid saponins (AFS) on RA using a type II collagen (CII)-induced arthritis (CIA) rat model, and to assess the anti-inflammatory effects of the main active compounds of AFS, namely flaccidoside II, anhuienoside E, glycoside St-I4a, hemsgiganoside B, hederasaponin B, and 3-O-α-l-rhamnopyranosyl (1 → 2)-β-d-glucopyranosyl oleanolic acid 28-O-β-d-glucopyranosyl (1 → 6)-β-d-glucopyranosyl ester. Methods: Male Wistar rats (n = 50) were randomly separated into five groups (n = 10) and immunized by CII injection. AFS (200 or 40...
Source: Chinese Medicine - July 25, 2015 Category: Complementary Medicine Authors: Qing LiuXiu-Zhen ZhuRui-Bing FengZhong LiuGui-Yang WangXi-Feng GuanGuo-min OuYao-Lan LiYing WangMan-Mei LiWen-Cai Ye Source Type: research

Ephedra protects vascular endothelium cells from vinorelbine‐induced cytotoxicity by preserving endothelial nitric oxide synthase activity
ConclusionEphedra extract preserved eNOS phosphorylation following vinorelbine‐induced oxidative stress, thereby protecting cells from vinorelbine‐induced cytotoxicity. Moreover, the protective effect of ephedra extract is dependent on the increase of [Ca2+]i and the Ca2+/calmodulin‐dependent signal transduction pathway. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 25, 2015 Category: Complementary Medicine Authors: Ken Konaka, Kota Moriyama, Naoto Okada, Hirotaka Nishisako, Masayuki Shono, Kazuyoshi Kawazoe, Keisuke Ishizawa Tags: ORIGINAL ARTICLE Source Type: research

Review of dietary supplements for the management of osteoarthritis in dogs in studies from 2004 to 2014
Osteoarthritis (OA) is a chronic, painful, degenerative and inflammatory disease that affects the synovial joints and leads finally to the loss of mobility. It is highly prevalent in dogs. Nowadays, no cure exists, and the pharmacological treatment is limited to clinical signs alleviation. Some positive beneficial effects have been highlighted with dietary supplements in the course of dog OA. The goals of this narrative review are to summarize the scientific data available in the literature on dietary supplements assessed in dog OA and to discuss some trails about how to improve several aspects of research and issues with ...
Source: Journal of Veterinary Pharmacology and Therapeutics - July 24, 2015 Category: Veterinary Research Authors: F. Comblain, S. Serisier, N. Barthelemy, M. Balligand, Y. Henrotin Tags: Review Article Source Type: research

Identification of bio-active components in leaf extracts of Aloe vera, Ocimum tenuiflorum (Tulasi) and Tinospora cordifolia (Amrutballi)
Plants are an integral part of life in many indigenous communities. Besides, being the source of food, fodder, fuel, etc., the use of plants as herbal medicines in curing several ailments goes parallel with the human civilization. The present study was carried out to identify the bio-active compounds in various leaf extracts of Aloe vera, Ocimum tenuiflorum and Tinospora cordifolia using dif... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - July 24, 2015 Category: Complementary Medicine Source Type: research

Serjania erecta Radlk. improves endothelial function in isolated aortic rings
Arterial hypertension presents a high incidence in the population, and it is a chronic degenerative disease. The roots of Serjania erecta Radlk. popularly known as cip-cinco-folhas, are used as a decoction against hypertension. This plant belongs to the Sapindaceae family and is plentiful in the Brazilian swamps. The present study was designed to study the effects of daily intake of S. erect... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - July 24, 2015 Category: Complementary Medicine Source Type: research

Bavachalcone Enhances RORα Expression, Controls Bmal1 Circadian Transcription, and Depresses Cellular Senescence in Human Endothelial Cells.
Authors: Dang Y, Ling S, Ma J, Ni R, Xu JW Abstract The circadian clock regulates many aspects of (patho)physiology in the central nervous system and in the peripheral tissues. RAR-related orphan receptor α (RORα), an orphan nuclear receptor, is involved in circadian rhythm regulation, including regulation of cardiovascular function. Bavachalcone, a prenylchalcone, is a major bioactive chalcone isolated from Psoralea corylifolia. This natural ingredient activated RORα1 luciferase reporter activity on drug screening. In addition, bavachalcone induced RORα1 expression in mRNA and protein levels in a dose-dependen...
Source: Evidence-based Complementary and Alternative Medicine - July 24, 2015 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Clinical Effect of Shenfu Injection in Patients with Septic Shock: A Meta-Analysis and Systematic Review.
Conclusions. Based on the findings in present review, Shenfu injection is more effective than conventional therapy in increasing mean arterial pressure, normalizing heart rate, clearing serum lactate, and reducing mortality. These results should be confirmed in higher level clinical trials in the future. PMID: 26199638 [PubMed] (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - July 24, 2015 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Effect of Luteolin on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney.
Authors: Tang L, Deng B, Shi L, Wei B, Ren B, Fu X Abstract 11Beta-hydroxysteroid dehydrogenase (11β-HSD) enzymes control the glucocorticoid (GC) signaling, which is essential in regulating homeostasis. Our previous study revealed that Eclipta prostrata (EP) affected the activity and expression of 11β-HSD enzymes which might improve the efficacy and reduce the adverse drug effects of glucocorticoid in patients undergoing combinational therapy. However, it is still unclear which composition of EP plays a major role and how it works. In this paper, we chose Luteolin which is one of the main ingredients of EP and ev...
Source: Evidence-based Complementary and Alternative Medicine - July 24, 2015 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Liquiritigenin Protects Rats from Carbon Tetrachloride Induced Hepatic Injury through PGC-1α Pathway.
Authors: Zhang Y, He Y, Yu H, Ma F, Wu J, Zhang X Abstract The lack of effective treatment for liver cirrhosis and hepatocellular carcinomas imposes serious challenges to the healthcare system. Here, we investigated the efficacy and mechanism of liquiritigenin involved in preventing or retarding the progression of liver diseases in a rat model with chronic carbon tetrachloride (CCl4) exposure. Sprague Dawley rats were given CCl4 and lliquiritigenin alone or simultaneously for 8 weeks before liver was harvested to check histological changes by Hematoxylin and Eosin (H&E) staining, apoptosis by TUNEL assay, ROS b...
Source: Evidence-based Complementary and Alternative Medicine - July 24, 2015 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research