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Complementary Medicine

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.

Short-term periodic consumption of multiprobiotic from childhood improves insulin sensitivity, prevents development of non-alcoholic fatty liver disease and adiposity in adult rats with glutamate-induced obesity
Conclusions: These results have shown that periodic treatment with multiprobiotic prevents the MSG-induced obesity and NAFLD development. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 16, 2014 Category: Complementary Medicine Authors: Oleksandr SavcheniukNazarii KobyliakMaryana KondroOleksandr VirchenkoTetyana FalalyeyevaTetyana Beregova Source Type: research

Design of a randomised acupuncture trial on functional neck/shoulder stiffness with two placebo controls
DiscussionIn addition to intention-to-treat analysis, we will conduct subgroup analysis based on practitioners' or patients' guesses to discuss the efficacy and effectiveness of treatments with skin piercing and various placebo controls. The results of practitioner and patient blinding will be discussed. We believe this study will further distinguish the role of different components of acupuncture.Trial registration: Current Controlled Trial ISRCTN76896018 (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 16, 2014 Category: Complementary Medicine Authors: Nobuari TakakuraMiho TakayamaAkiko KawaseTed KaptchukJian KongHiroyoshi Yajima Source Type: research

Antifungal and cytotoxicity activities of the fresh xylem sap of Hymenaea courbaril L. and its major constituent fisetin
Conclusion: Naturally occurring fisetin can provide excellent starting points for clinical application and can certainly represent a therapeutic potential against fungal infections, because it showed in vitro antifungal activity and low toxicity on animal cells. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 16, 2014 Category: Complementary Medicine Authors: Maysa da CostaMarize BozinisWanessa AndradeCarolina CostaAlessandro da SilvaCecília Alves de OliveiraLucília KatoOrionalda FernandesLúcia SouzaMaria Silva Source Type: research

Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats
Conclusion: Our research exertion clearly indicates the considerable antihyperglycemic, antihyperlipidemic, antioxidant & pancreas/renal/hepatic/cardiac protective action of ALEx. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 16, 2014 Category: Complementary Medicine Authors: Danish AhmedVikas KumarAmita VermaPushpraj GuptaHemant KumarVishal DhingraVatsala MishraManju Sharma Source Type: research

A case of mucocutaneous leishmaniasis diagnosed by serology
Abstract A 43‐year‐old Japanese Bolivian male had been suffering from a right leg ulcer after an insect bite during his residence in Bolivia. The ulcer healed after herbal medicine treatment. Ten years later, the patient had symptoms of nasal obstruction, nasal bleeding, and pharyngodynia, which were accompanied by a destructive ulcer with surrounding erythema involving the right nostril apex and columella. Papillary, irregular mucosal lesions were seen on the soft palate. Giemsa staining and polymerase chain reaction (PCR) using biopsy specimens of the papillary mucosal lesions on the soft palate failed to identify Le...
Source: The Journal of Dermatology - July 16, 2014 Category: Dermatology Authors: Yoko Okumura, Asako Yamauchi, Isao Nagano, Makoto Itoh, Keisuke Hagiwara, Kenzo Takahashi, Hiroshi Uezato, Manabu Maeda, Mariko Seishima Tags: Concise Communication Source Type: research

Carnosic Acid Stimulates Glucose Uptake in Skeletal Muscle Cells via a PME-1/PP2A/PKB Signalling Axis.
In this study, we hypothesized that CA may act to improve glycaemic status through enhancing peripheral glucose clearance. Herein, we demonstrate that CA acts to mimic the metabolic actions of insulin by directly stimulating glucose uptake in rat skeletal L6 myotubes, concomitant with increased translocation of the GLUT4 glucose transporter to the plasma membrane. Mechanistically, CA-induced glucose transport was found to be dependent on protein kinase B (PKB/Akt) but not AMPK, despite both kinases being activated by CA. Crucially, in accordance with its ability to activate PKB and stimulate glucose uptake, we show that CA...
Source: Cellular Signalling - July 16, 2014 Category: Cytology Authors: Lipina C, Hundal HS Tags: Cell Signal Source Type: research

Acupuncture for smoking cessation: where now?
PMID: 25030215 [PubMed - as supplied by publisher] (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - July 16, 2014 Category: Complementary Medicine Authors: White A, Taylor A Tags: Acupunct Med Source Type: research

Survey of plants popularly used for pain relief in Rio Grande do Sul, southern Brazil
In conclusion, the folk use of native plants with therapeutic purposes is widespread in RS State (Brazil), being pain relief an important property. (Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - July 15, 2014 Category: Drugs & Pharmacology Source Type: research

Ethnopharmacology in Ireland: an overview
This study attempts to attest, observe and comment on the diversity of plants, as well as the accompanying information which inevitably is vital for the future development of herbal medicines for human therapy. Initially, the information in relation to medicinal plants in Ireland only was extracted from the above-mentioned book and organised in tables. Afterwards, it was analysed through the construction of maps and the positioning of each piece of information in specific geographical regions of the country. Its division into provinces was taken into consideration as well as into counties within the provinces. These maps a...
Source: Revista Brasileira de Farmacognosia - July 15, 2014 Category: Drugs & Pharmacology Source Type: research

Traditional use and safety of herbal medicines
In the European Union, traditional herbal medicines that are regarded as "acceptably safe, albeit not having a recognized level of efficacy" fit into a special category of drugs ("traditional herbal medicine products") for which requirements of non-clinical and clinical studies are less rigorous. A regulation proposal published by the Brazilian National Health Surveillance (Anvisa) defines a similar drug category ("traditional phytotherapeutic products") for registration purposes. Regarding herbal medicines, both agencies seem to be lenient regarding proof of efficacy, and consider long-standing folk use as evidence of saf...
Source: Revista Brasileira de Farmacognosia - July 15, 2014 Category: Drugs & Pharmacology Source Type: research

Sale of medicinal herbs in pharmacies and herbal stores in Hurlingham district, Buenos Aires, Argentina
In this paper, the sale of medicinal plants was described in the urban city of Buenos Aires, Argentina. Semi-structured interviews were conducted with pharmacists and herb store owners about different characteristics of retail. Likewise, different types of retailers were compared, and the phytomedicine degree of acceptance was consulted. The percentage of customers who buy medicinal plants in herb stores is higher than in pharmacies. The five most demanded species were: "malva" (Malva sp.), 18%; "manzanilla" (Matricaria recutita), 13%; "tilo" (Tilia sp.), 12%; "cuasia" (Picrasma crenata), 8%; and "boldo" (Peumus boldus), 7...
Source: Revista Brasileira de Farmacognosia - July 15, 2014 Category: Drugs & Pharmacology Source Type: research

Public Notification: Lingzhi Cleansed Slim Tea Contains Hidden Drug Ingredient
FDA Public Notification [07-08-2014] The Food and Drug Administration (FDA) is advising consumers not to purchase or use Lingzhi Cleansed Slim Tea, a product promoted and sold for weight loss on various websites and possibly in some retail stores. (Source: NCCAM Featured Content)
Source: NCCAM Featured Content - July 15, 2014 Category: Complementary Medicine Authors: NCCAM Source Type: news

Efficacy of Auriculotherapy for Constipation in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The Journal of Alternative and Complementary Medicine , Vol. 0, No. 0. (Source: The Journal of Alternative and Complementary Medicine)
Source: The Journal of Alternative and Complementary Medicine - July 15, 2014 Category: Complementary Medicine Tags: article Source Type: research

Giving voice to cancer patients: assessing non‐specific effects of an integrative oncology therapeutic program via short patient narratives
ConclusionsShort patient narratives should be considered for patient‐reported outcomes, expressing perspectives of both effects and experience of care. CM may promote patient QoL‐related outcomes through non‐specific effects, enhancing patient‐centered care. The benefits of CM dependent on general therapeutic incidental aspects (i.e., common factors) warrant attention regarding non‐specific components of treatment. Copyright © 2014 John Wiley & Sons, Ltd. (Source: Psycho-Oncology)
Source: Psycho-Oncology - July 15, 2014 Category: Cancer & Oncology Authors: Yael Keshet, Elad Schiff, Noah Samuels, Eran Ben‐Arye Tags: Paper Source Type: research

How to manage the chronic pelvic pain syndrome in men presenting to sexual health services
Background Chronic pelvic pain syndrome (CPPS) in men is an important and common condition in genitourinary medicine (GUM) and other sexual health services. It has a lifetime prevalence of 2%–14%.1–4 The terms CPPS and chronic prostatitis are often used interchangeably to describe a syndrome which causes perineal and genital pain that can be unrelenting and physically, as well as emotionally, exhausting.1–5 The median age of patients affected is 43 years and the syndrome is usually of sudden onset,2 4 though classically CPPS is only diagnosed when symptoms have been present for at least 3 months...
Source: Sexually Transmitted Infections - July 15, 2014 Category: Sexual Medicine Authors: Crofts, M., Mead, K., Persad, R., Horner, P. Tags: Drugs: infectious diseases, Urinary tract infections, Sexual and gender disorders, Complementary medicine, Prostatitis, Sexual and gender disorders, Sexual dysfunction, Urethritis, Vulvovaginal disorders, Prostate, Urinary tract infections Education Source Type: research

Ethnobotanical and economic value of Ravenala madagascariensis Sonn. in Eastern Madagascar
Conclusions: Ravenala madagascariensis is very important to the Ambalabe communities because for local population, it represents the Betsimisaraka cultural and traditional use of the plant for house building. Moreover, none of its parts are discarded. The harvest and sale of R. madagascariensis for building materials can also provide an additional source of income to the family. Besides, using Ravenala in house construction reduces the use of slow growing trees and contributes to the sustainable use of natural forest resources. (Source: Journal of Ethnobiology and Ethnomedicine)
Source: Journal of Ethnobiology and Ethnomedicine - July 15, 2014 Category: Complementary Medicine Authors: Nivo RakotoariveloAina RazanatsimaFortunat RakotoarivonyLucien RasoavietyAro RamarosandratanaVololoniaina JeannodaAlyse KuhlmanArmand RandrianasoloRainer Bussmann Source Type: research

Haptic Simulation for Acupuncture Needle Manipulation
The Journal of Alternative and Complementary Medicine , Vol. 0, No. 0. (Source: The Journal of Alternative and Complementary Medicine)
Source: The Journal of Alternative and Complementary Medicine - July 14, 2014 Category: Complementary Medicine Tags: article Source Type: research

Pain and Opioid Use in U.S. Soldiers: The Imperative for Researching Effective Pain Management Options in the Military
In this blog post, NCCAM Director Dr. Josephine Briggs explains the Center’s efforts to help address the serious problems of chronic pain and opioid use among members of the U.S. military. (Source: NCCAM Featured Content)
Source: NCCAM Featured Content - July 14, 2014 Category: Complementary Medicine Authors: Josephine P. Briggs, M.D. Source Type: news

Silent, not deadly; how farts cure diseases
A recent study from the University of Exeter has been reported as showing that smelling farts can cure cancer, as well as many other diseases. Although the study itself doesnt actually say this at any point, if farts do have healing powers it would have numerous wide-reaching implications Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - July 14, 2014 Category: Science Authors: Dean Burnett Tags: Science Health Biology Science and scepticism Alternative medicine & wellbeing Media Source Type: news

Oryeongsan inhibits LPS-induced production of inflammatory mediators via blockade of the NF-kappaB, MAPK pathways and leads to HO-1 induction in macrophage cells
Conclusions: We further demonstrate the anti-inflammatory effects and inhibitory mechanism of OR in LPS-stimulated macrophages for the first time. OR contains strong anti-inflammatory activity and affects various mechanism pathways including NF-kappaB, MAPKs and HO-1. Our results suggest that OR has potential value to be developed as an inflammatory therapeutic agent from a natural substance. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 14, 2014 Category: Complementary Medicine Authors: You-Chang OhYun Hee JeongJeong-Ho HaWon-Kyung ChoJin Yeul Ma Source Type: research

Antibacterial activities of Beilschmiedia obscura and six other Cameroonian medicinal plants against multi-drug resistant gram-negative phenotypes
Conclusion: The overall results of the present investigation provide information for the possible use of the methanol extracts of the studied plant species, especially B. obscura to fight infectious diseases caused by Gram-negative bacteria including MDR phenotypes. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 14, 2014 Category: Complementary Medicine Authors: Aimé FankamJules KuiateVictor Kuete Source Type: research

Ameliorating effects of Juzentaihoto on restraint stress and -induced alveolar bone loss
Juzentaihoto (JTX) is a traditional Japanese medicine that consists of 10 herbs. The purpose of this study was to evaluate the efficacy of multi-herbal medicine JTX as a preventive and therapeutic drug for periodontal bone resorption and for reducing restraint stress. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - July 14, 2014 Category: Dentistry Authors: Orie Takeda, Toshizo Toyama, Kiyoko Watanabe, Takenori Sato, Kenichi Sasaguri, Susumu Akimoto, Sadao Sato, Toshitsugu Kawata, Nobushiro Hamada Source Type: research

SafetyNET: An interdisciplinary research program to support a safety culture for spinal manipulation therapy
Conclusion: One outcome of the SafetyNET initiative is to provide a model for other disciplines and jurisdictions with respect to improving safety in procedures common to several regulated health disciplines.This article belongs to the Special Issue: Ensuring and Improving Patients Safety in Integrative Health Care. (Source: European Journal of Integrative Medicine)
Source: European Journal of Integrative Medicine - July 14, 2014 Category: Complementary Medicine Authors: Sunita Vohra, Greg N. Kawchuk, Heather Boon, Timothy Caulfield, Katherine A. Pohlman, Maeve O’Beirne Tags: Original articles Source Type: research

The battle between Big Pharma and herbal supplements
(NaturalNews) Dr. Mehmet Oz appeared before the Senate Subcommittee on Consumer Protection on Tuesday. He was charged with making false weight-loss claims and was there to testify. Chairwoman of the subcommittee Senator Claire McCaskill stated, "You are being made an example of today... (Source: NaturalNews.com)
Source: NaturalNews.com - July 13, 2014 Category: Consumer Health Advice Source Type: news

Angelica sinensis Induces Hair Regrowth via the Inhibition of Apoptosis Signaling.
Abstract Hair loss is accompanied by keratinocyte apoptosis-regression during catagen and prolonged telogen. Angelica sinensis was reported to promote hair growth in vitro. Based on previous studies, we explored the hair growth effect and the mechanism of A. sinensis related to keratinocyte apoptosis-regression during catagen in mice. The 70% Ethanol extract of A. sinensis was applied topically at doses of 1 and 100 mg/mL to the dorsa of C57BL/6 mice for 2 weeks. The A. sinensis-treated group showed noticeable hair regrowth. Treatment with A. sinensis restored the lengths of hair shafts and size of hair follicles. ...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Kim MH, Choi YY, Cho IH, Hong J, Kim SH, Yang WM Tags: Am J Chin Med Source Type: research

Gastrodia elata Shows Neuroprotective Effects via Activation of PI3K Signaling against Oxidative Glutamate Toxicity in HT22 Cells.
Abstract Dried roots of Gastrodia elata have traditionally been used in Korean medicine for the treatment of neurological disorders such as scotodinia, paralysis, and epilepsy. In our study, we attempted to investigate the neuroprotective effects of methanol extract from G. elata (MEGE) against glutamate-mediated oxidative stress and to explore underlying neuroprotective mechanisms. Analyses for cell viability, lactate dehydrogenase (LDH), flow cytometry, Western blot, and reactive oxygen species (ROS) were performed in HT22 hippocampal cells. Pretreatment with MEGE resulted in a potent neuroprotective effect again...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Han YJ, Je JH, Kim SH, Ahn SM, Kim HN, Kim YR, Choi YW, Shin HK, Choi BT Tags: Am J Chin Med Source Type: research

Chinese Prescription Kangen-karyu and Salviae Miltiorrhizae Radix Improve Age-Related Oxidative Stress and Inflammatory Response through the PI3K/Akt or MAPK Pathways.
This study examined whether Kangen-karyu and its crude drug, Salviae Miltiorrhizae Radix, have a reno-protective effect on the age-related oxidative stress and inflammatory response through the phosphoinositide 3-kinase (PI3K)/Akt or mitogen-activated protein kinase (MAPK) pathways in aged rats. Kangen-karyu or Salviae Miltiorrhizae Radix (20 mg/kg body weight/day) was administered orally to old groups of rats for 16 days, and their effects were compared with the vehicle-treated old and young rats. The administration of Kangen-karyu caused a slight decrease in the serum glucose level and a significant decrease in the serum...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Park CH, Kim DH, Park MH, Kim MK, Kim ND, Kim CM, Tanaka T, Yokozawa T, Chung HY, Moon HR Tags: Am J Chin Med Source Type: research

Salvia plebeia Suppresses Atopic Dermatitis-Like Skin Lesions.
In this study, we investigated the effects of S. plebeia extract (SPE) on atopic dermatitis (AD)-like skin lesions and defined underlying mechanisms of action. We established an AD model in BALB/c mice by repeated local exposure of house dust mite extract (Dermatophagoides farinae extract, DFE) and 2,4-dinitrochlorobenzene (DNCB) to the ears. Repeated alternative treatment of DFE/DNCB caused AD-like skin lesions. The oral administration of SPE decreased AD symptoms based on ear thickness and histopathological analysis, in addition to serum IgE and IgG2a levels. SPE suppressed mast cell infiltration into the ear and serum h...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Choi JK, Oh HM, Lee S, Kwon TK, Shin TY, Rho MC, Kim SH Tags: Am J Chin Med Source Type: research

Millettia pachycarpa Exhibits Anti-Inflammatory Activity Through the Suppression of LPS-Induced NO/iNOS Expression.
Abstract The present study was designed to investigate the in vitro and in vivo anti-inflammatory activity of flavonoids isolated from Millettia pachycarpa Benth. The seeds of M. pachycarpa Benth were extracted with ethanol and subjected to chromatographic separation for the isolation of bioactive compounds. Their structures were elucidated by spectroscopic methods. The anti-inflammatory activity of the compounds was investigated by evaluating the inhibition ability of NO production, iNOS activity and iNOS protein expression induced by LPS-stimulated RAW264.7 macrophages in vitro and the carrageenan-induced hind pa...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Ye H, Xie C, Wu W, Xiang M, Liu Z, Li Y, Tang M, Li S, Yang J, Tang H, Chen K, Long C, Peng A, Chen L Tags: Am J Chin Med Source Type: research

Suppressive effects of britanin, a sesquiterpene compound isolated from inulae flos, on mast cell-mediated inflammatory responses.
Abstract Mast cells are central players in immediate-type hypersensitvity and inflammatory responses. In the present study, the effects of britanin on the passive cutaneous anaphylaxis (PCA) reaction in mice and on the phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-induced production of pro-inflammatory cytokines in human mast cell line (HMC-1) were evaluated. The oral administration of britanin (10-20 mg/kg) decreased the mast cell-mediated PCA reaction in IgE-sensitized mice. In the activity and mechanism of britanin in vitro assay, britanin suppressed the gene expression and secretion of pr...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Park HH, Kim SG, Park YN, Lee J, Lee YJ, Park NY, Jeong KT, Lee E Tags: Am J Chin Med Source Type: research

Humulus scandens Exhibits Immunosuppressive Effects in Vitro and in Vivo by Suppressing CD4(+) T Cell Activation.
In this study, the major active faction of Humulus scandens (H.S) was prepared. Then, its immunosuppressive effects and underlying mechanisms on T cell activation were investigated in vitro and in vivo. Results showed that H.S significantly inhibited the proliferation of splenocytes induced by concanavalin A, lipopolysaccharides, and mixed-lymphocyte reaction in vitro. Additionally, H.S could dramatically suppress the proliferation and interferon-γ (IFN-γ) production from T cells stimulated by anti-CD3 and anti-CD28. Flow cytometric results confirmed that H.S could suppress the differentiation of IFN-γ-producing type 1 ...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Feng J, Wu Y, Yang Y, Jiang W, Hu S, Li Y, Yang Y Tags: Am J Chin Med Source Type: research

Flavonoids from Litsea coreana Decreases TNF-α Secretion from Peritoneal Macrophages in Adjuvant-Induced Arthritis Rats via UPR Pathway.
This study was designed to detect the effects of total flavonoids from Litsea coreana Levl. (TFLC) on the complete Freund's adjuvant-induced (CFA-induced) arthritis (AA) in rats and to explore whether inflammatory cytokines were induced by the IRE1/mTORC1/TNF-α-dependant mechanism in peritoneal macrophages. In vivo, our data indicated that TFLC (100, 200 mg/kg, i.g. × 10 days) could significantly suppress secondary paw swelling and serum levels of TNF-α and IL-1β. Histopathological figures showed that TFLC treatment improved the morphologic changes of articular cartilages and synovium. Results of RT-PCR and western blo...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Zhong J, Ma T, Huang C, Liu H, Chen Z, Cao L, Li X, Li J Tags: Am J Chin Med Source Type: research

Anti-Inflammatory Effect of Lycii radicis in LPS-Stimulated RAW 264.7 Macrophages.
In this study, the anti-inflammatory effect of LRC was investigated in lipopolysaccharide (LPS)-stimulated mouse macrophage, RAW 264.7 cells. LRC extract significantly decreased the LPS-induced production of inflammatory mediators, nitric oxide (NO), prostaglandin (PG) E2 and pro-inflammatory cytokines, interleukin (IL)-1β and IL-6 in the cells. In addition, LRC extract inhibited the LPS-induced expression of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 mRNA and protein, and inflammatory cytokines mRNA in the cells. The action mechanism of LRC underlies the blocking of LPS-mediated p38 and Jun N-terminal kinase...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Song MY, Jung HW, Kang SY, Kim KH, Park YK Tags: Am J Chin Med Source Type: research

Lotus Leaf (Nelumbo nucifera) and its Active Constituents Prevent Inflammatory Responses in Macrophages via JNK/NF-κB Signaling Pathway.
In this study, we investigated the leaves of Nelumbo nucifera Gaertn, an aquatic perennial plant cultivated in eastern Asia and India, in anti-inflammatory pharmacological effects in the murine macrophage cell line RAW264.7. Results showed that lipopolysaccharide (LPS) increased the protein expression of inducible nitric oxide synthase (iNOS) and COX-2, as well as the mRNA expression and level of IL-6 and TNF-α, while NNE significantly reduced these effects of LPS. LPS also induced phospho-JNK protein expression. The JNK-specific inhibitor SP600125 decreased the proteins expression of phospho-JNK, iNOS, COX-2, and the mRN...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Liu SH, Lu TH, Su CC, Lay IS, Lin HY, Fang KM, Ho TJ, Chen KL, Su YC, Chiang WC, Chen YW Tags: Am J Chin Med Source Type: research

Anti-Hepatitis C Virus Activity of Crude Extract and Fractions of Entada africana in Genotype 1b Replicon Systems.
This study reports for the first time, the effects of Ea crude extract and fractions on HCV replication. Furthermore, the effect of one Ea fraction on the transcriptional expression of two interferon-stimulated genes (ISGs) was also investigated. A methylene chloride-methanol (MCM) stem bark crude extract and different MCM fractions (EaF0, EaF5, EaF10, EaF25, and EaF100) were prepared and tested on LucUbiNeo-ET and Huh 5.15 cells lines used as genotype 1b (GT1b) replicon systems. The cells were incubated with crude extract and fractions at various concentrations. Then, the antiviral activity was assessed by luciferase repo...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Galani Tietcheu BR, Sass G, Njayou NF, Mkounga P, Tiegs G, Moundipa PF Tags: Am J Chin Med Source Type: research

Ocimum gratissimum is Effective in Prevention against Liver Fibrosis in Vivo and in Vitro.
In this study, we tested in vivo and in vitro the effectiveness of O. gratissimum extracts (OGEs) in anti-hepatic fibrosis in rats. Male Wistar rats were administered with carbon tetrachloride (CCl4) by intraperitoneal injection and varying amounts of oral injection of OGE doses (0-40 mg/kg body weight) for 8 weeks. Our experiments showed that OGE significantly reduced liver damage, including steatosis and fibrosis, in a dose-dependent manner, as well as significantly decreased the elevation in plasma aspartate aminotransferase (AST) and alanine aminotransferase (ALT). It also inhibited the formation of lipid peroxidative ...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Chiu YW, Chao PY, Tsai CC, Chiou HL, Liu YC, Hung CC, Shih HC, Lai TJ, Liu JY Tags: Am J Chin Med Source Type: research

Treatment of stress urinary incontinence by ginsenoside rh2.
In conclusion, the ginsenoside Rh2 may offer therapeutic potential against SUI. PMID: 25004877 [PubMed - in process] (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Chen YH, Lin YN, Chen WC, Hsieh WT, Chen HY Tags: Am J Chin Med Source Type: research

Notoginsenoside R1 Attenuates Hypoxia and Hypercapnia-Induced Vasoconstriction in Isolated Rat Pulmonary Arterial Rings by Reducing the Expression of ERK.
Abstract Pulmonary arterial hypertension (PAH) is a disease of the small pulmonary arteries characterized by increased vascular resistance. Pulmonary vasoconstriction has been proven to play a pivotal role in PAH. We have previously hypothesized that Panax notoginseng saponins (PNS) might attenuate hypoxia-hypercapnia-induced pulmonary vasoconstriction. The specific objective of the present study was to investigate the role of notoginsenoside R1, a main ingredient of PNS, in this process and the possible underlying mechanism. The third order pulmonary rings from the Sprague-Dawley rats were treated with different c...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Xu Y, Lin L, Tang L, Zheng M, Ma Y, Huang L, Meng W, Wang W Tags: Am J Chin Med Source Type: research

Baicalein Inhibits HMGB1 Release and MMP-2/-9 Expression in Lipopolysaccharide-Induced Cardiac Hypertrophy.
Abstract Myocardial dysfunction, a common complication after sepsis, significantly contributes to the death of patients with septic shock. In the search for potentially effective drugs to decrease mortality from sepsis, we investigated the cardioprotective effects of baicalein, a flavonoid present in the root of Scutellaria baicalensis, on lipopolysaccharide (LPS)-induced pro-inflammatory cytokine production and matrix metalloproteinase-2 and -9 (MMP-2/-9) expression. We found that baicalein significantly attenuated LPS-induced cardiac hypertrophy and counteracted reactive oxygen species (ROS) generation in neonata...
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Chen HM, Liou SF, Hsu JH, Chen TJ, Cheng TL, Chiu CC, Yeh JL Tags: Am J Chin Med Source Type: research

Ginkgo biloba on Focal Cerebral Ischemia: A Systematic Review and Meta-Analysis.
In conclusion, EGB exerts a significant protective effect on experimental focal cerebral ischemia. However, possible experimental bias should be taken into account in future clinical studies. PMID: 25004874 [PubMed - in process] (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - July 12, 2014 Category: Complementary Medicine Authors: Yin B, Xu Y, Wei R, Luo B Tags: Am J Chin Med Source Type: research