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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 16.

Effects of Kaixin Powder on Expression of 5-HT Receptor in Hippocampus of Depressed Rats Induced by CUMS
Conclusion The result indicated that the depression performance of depressed rats induced by CUMS can be ameliorated by Kaixin Powder, and the mechanism maybe concerned with increasing the contents of 5-HT, exciting 5-HT1A receptor, and antagonising 5-HT2A receptor. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

Anti-inflammation of Tripterygium wilfordii Polycoride on Macrophages and Its Regulation to Inflammation via TLR4/NF-κB
Conclusion The research shows that down regulation of TLR4 and NF-kB p65 may be one of the mechanisms about the TWP inhibitory effect on TNF-α and IL-1β. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

Total Flavonoids from Flowers of Abelmoschus manihot for Amelioration of α-naphthylisothiocyanate-induced Cholestasis by Regulating Expression of Transporters
Conclusion TFA exerts a therapeutic effect on ANIT-induced liver injury in rats with cholestasis, possibly through regulating the expressions of hepatic transporters. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

Inhibition of Magnolol and Honokiol on Cytochrome P450 Enzymes in Rat and Human Liver Microsomes
Conclusion HN is a moderate or weak inhibitor of human CYP1A2. Both MN and HN are weak or non inhibitors of the other tested human CYP isoforms. The results suggest that no significant metabolic interaction seems likely to occur when the substrate drugs of CYP isoforms tested in the present work are co-administered with MN and HN. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

Xiyanping Injection in Treatment of Viral Pneumonia in Children: A Meta-analysis of Random Control Trials
Conclusion The existing research indicated that Xiyanping Injection is a secure and efficient scheme for viral pneumonia in children. Because of the poor quality of present researches, these results should be verified by strictly-designed and large-scale sample RCTs. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

Saponin Accumulation in Flower Buds of Panax notoginseng
Conclusion The saponin contents from the flower buds of P. notoginseng vary depending on the growth area and duration. The fingerprints show that the saponin contents and compositions vary depending on the part of P. notoginseng. These results are useful for the pharmacological evaluation and quality control of P. notoginseng. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

Simultaneous Determination of Two Major Triterpenoid Saponins: Celosins I and II in Celosiae Semen by HPLC-ELSD
Conclusion The sun light may be a key factor influencing the contents of the two saponins, indicating that the environment has a great impact on the quality of Celosiae Semen. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

A New Geranylated 2-Arylbenzofuran from Morus alba
Conclusion Compound 1 is a new geranylated 2-arylbenzofuran. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 23, 2015 Category: Complementary Medicine Source Type: research

In vitro simulation of the equine hindgut as a tool to study the influence of phytosterol consumption on the excretion of anabolic–androgenic steroids in horses
Publication date: Available online 18 June 2015 Source:The Journal of Steroid Biochemistry and Molecular Biology Author(s): A.I. Decloedt , L. Bailly-Chouriberry , J.Vanden Bussche , P. Garcia , M-A Popot , L. Vanhaecke Traditionally, steroids other than testosterone are considered to be synthetic, anabolic steroids. Nevertheless, in stallions, it has been shown that β-Bol can originate from naturally present testosterone. Other precursors, including phytosterols from feed, have been put forward to explain the prevalence of low levels of steroids (including β-Bol and ADD) in urine of mares and geldings. However, the po...
Source: The Journal of Steroid Biochemistry and Molecular Biology - June 23, 2015 Category: Biochemistry Source Type: research

Vanda roxburghii chloroform extract as a potential source of polyphenols with antioxidant and cholinesterase inhibitory activities: identification of a strong phenolic antioxidant
Conclusion: These results suggest that the chloroform extract of V. roxburghii, possibly due to its phenolic compounds, exert potential antioxidant and cholinesterase inhibitory activities, which may be useful in the treatment of AD. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - June 23, 2015 Category: Complementary Medicine Authors: Md. UddinRejina AfrinMd. UddinMd. UddinA. AlamAziz RahmanGolam Sadik Source Type: research

The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cells
Background: The green tea catechin epigallocatechin gallate (EGCG) was shown to effectively inhibit tumor growth in various types of cancer including biliary tract cancer (BTC). For most BTC patients only palliative therapy is possible, leading to a median survival of about one year. Chemoresistance is a major problem that contributes to the high mortality rates of BTC. The aim of this study was to investigate the cytotoxic effect of EGCG alone or in combination with cisplatin on eight BTC cell lines and to investigate the cellular anti-cancer mechanisms of EGCG. Methods: The effect of EGCG treatment alone or in combinatio...
Source: BMC Complementary and Alternative Medicine - June 23, 2015 Category: Complementary Medicine Authors: Christian MayrAndrej WagnerDaniel NeureiterMartin PichlerMartin JakabRomana IlligFrieder BerrTobias Kiesslich Source Type: research

Suppression of acute pancreatitis by L-lysine in mice
Background: Acute pancreatitis is an inflammatory disease caused by several factors such as viral infection, drugs, and diagnostic endoscopy. The aim of this study was to evaluate the potential protective or therapeutic effects of L-lysine on pancreatitis induced by L-arginine in mice. Methods: Four groups of mice (10 in each group) were assessed. Group I was the control. Animals in groups II–IV were injected intraperitoneally with L-arginine hydrochloride (400 mg/kg body weight [bw]) for 3 days. Group III animals were orally pre-treated with L-lysine (10 mg/kg bw), whereas group IV animals were orally post-treated wi...
Source: BMC Complementary and Alternative Medicine - June 23, 2015 Category: Complementary Medicine Authors: Abdulrahman Al-Malki Source Type: research

Ethnic differences in medicinal plant use among University students: a cross-sectional survey of self-reported medicinal plant use at two Midwest Universities
Conclusions: Results are consistent with preexisting data showing higher rates of medicinal plant use among college students compared to the larger US population of adults and demonstrate previously documented health disparities in Native American populations compared to non-Native Americans. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - June 23, 2015 Category: Complementary Medicine Authors: Rachel CraftKatrina McClureSteven CorbettMaria FerreiraAshley StiffarmKelly Kindscher Source Type: research

Influence of different drying methods on drying period, essential oil content and composition of Lippia citriodora Kunth
Publication date: Available online 22 June 2015 Source:Journal of Applied Research on Medicinal and Aromatic Plants Author(s): M.T. Ebadi , M. Azizi , F. Sefidkon , N. Ahmadi The influence of four drying methods (shade drying, freeze drying, oven drying and vacuum drying at 40, 50 and 60°C) on the essential oil content and composition of lemon verbena (Lippia citriodora Kunth.) was evaluated. The essential oil content and composition of dried samples were determined by hydro-distillation using a Clevenger apparatus and gas chromatography (GC) and gas chromatography–mass spectrometry (GC–MS) respectively. Results sho...
Source: Journal of Applied Research on Medicinal and Aromatic Plants - June 23, 2015 Category: Complementary Medicine Source Type: research

Proteomic analysis of amino acid metabolism differences between wild and cultivated Panax ginseng
Conclusion This study elucidates the differences in amino acids between wild and cultivated ginseng. These results will provide a reference for further studies on the medicinal functions of wild ginseng. (Source: Journal of Ginseng Research)
Source: Journal of Ginseng Research - June 23, 2015 Category: Complementary Medicine Source Type: research

In-vitro antioxidant and antidiabetic potentials of Dianthus basuticus Burtt Davy whole plant extracts
This study evaluated the antioxidant and antidiabetic potential of Dianthus basuticus using an in-vitro model. The antioxidant activity was determined using iron chelation, 1,1-diphenyl–2 picrylhydrazyl (DPPH), hydroxyl and superoxide anion radical scavenging abilities of the aqueous, ethanol and hydro-ethanol extracts of D. basuticus while the antidiabetic potential was assessed by evaluating the inhibitory effects of the extracts on the activities of α-amylase, α-glucosidase, maltase and sucrase. Aqueous extract displayed significantly higher (p < 0.05) DPPH (2.56μg/mL) and superoxide radical (7.22μg/mL) sca...
Source: Journal of Herbal Medicine - June 23, 2015 Category: Complementary Medicine Source Type: research

Global identification and quantitative analysis of chemical constituents in traditional Chinese medicinal formula Qi-Fu-Yin by ultra-high performance liquid chromatography coupled with mass spectrometry
In this study, an ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UHPLC-QTOF MS) was developed for comprehensive analysis of chemical constituents in QFY. By using characteristic ions and fragmentation rules, a reliable identification of 156 compounds was described here, including 69 triterpene saponins, 23 oligosaccharide esters, 22 flavanoids, 9 alkaloids, 9 phenolic acids, 8 phthalides, 7 phenylethanoid glycosides, 3 xanthones, 3 sesquiterpene lactones, 2 ionones and 1 iridoid glycoside. Twenty-six major compounds were then determined in a single run by UHPLC...
Source: Journal of Pharmaceutical and Biomedical Analysis - June 23, 2015 Category: Drugs & Pharmacology Source Type: research

Dietary supplements consumption among cardiac patients admitted to internal medicine and cardiac wards.
CONCLUSIONS: Consumption of dietary supplements is common among cardiac patients. It is more common in those admitted to Internal Medicine Departments than in those admitted to the Cardiology Wards. Due to the risk of various drug-supplement interactions consumed by patients with cardiac diseases, there is a need to increase awareness and knowledge among medical staff regarding the intake of dietary supplements. PMID: 26100832 [PubMed - as supplied by publisher] (Source: Cardiology Journal)
Source: Cardiology Journal - June 23, 2015 Category: Cardiology Authors: Karny-Rahkovich O, Blatt A, Elbaz-Greener GA, Ziv-Baran T, Golik A, Berkovitch M Tags: Cardiol J Source Type: research

Puerarin attenuates glucocorticoid-induced apoptosis of hFOB1.19 cells through the JNK- and Akt-mediated mitochondrial apoptotic pathways.
In conclusion, puerarin prevented DEX‑induced apoptosis of hFOB1.19 cells via inhibition of the JNK pathway and activation of the PI3K/Akt signaling pathway in the cells, dependent on the mitochondrial apoptotic pathway. These results support puerarin as a promising target in the treatment of GC-induced osteoporosis. PMID: 26101183 [PubMed - as supplied by publisher] (Source: International Journal of Molecular Medicine)
Source: International Journal of Molecular Medicine - June 23, 2015 Category: Molecular Biology Authors: Yu D, Mu S, Zhao D, Wang G, Chen Z, Ren H, Fu Q Tags: Int J Mol Med Source Type: research

Effects of transcutaneous electrical nerve stimulation on rats with the third lumbar vertebrae transverse process syndrome.
CONCLUSIONS: TENS at both local (BL23) and distant (ST36) acupuncture points had a pain-relieving effect in rats with the third lumbar vertebrae transverse process syndrome, and LAS appeared to have greater anti-inflammatory and analgesic effects than DAS. TRIAL REGISTRATION NUMBER: 09073. PMID: 26104377 [PubMed - as supplied by publisher] (Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society)
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - June 23, 2015 Category: Complementary Medicine Authors: Li H, Shang XJ, Dong QR Tags: Acupunct Med Source Type: research

[Platelet-rich plasma in knee osteoarthritis treatment].
Abstract The biological changes that commonly cause degenerative articular cartilage injuries in the knee are primarily associated to misalignment of the joint and metabolic changes related to age, as occurs in osteoarthritis. Furthermore, the capacity for cartilage self-regeneration is quite limited due to the lack of vascularity of the tissue. To date there is no ideal treatment capable to stimulate cartilage regeneration; thus there is a need to seek alternative therapies for the treatment of such conditions. The number of publications demonstrating the therapeutic and regenerative benefits of using platelet-ric...
Source: Cirugia y Cirujanos - June 23, 2015 Category: Surgery Authors: Simental-Mendía MA, Vílchez-Cavazos JF, Martínez-Rodríguez HG Tags: Cir Cir Source Type: research

Essential Role of Constitutive Androstane Receptor in Ginkgo biloba Extract Induced Liver Hypertrophy and Hepatocarcinogenesis.
Abstract Ginkgo biloba extract (GBE) is commonly used as an herbal supplement. The National Toxicology Program (NTP) study of GBE reported clear evidence of hepatocarcinogenicity in mice. To clarify the mode of action (MOA) for hepatocarcinogenesis by GBE, we investigated the involvement of the constitutive androstane receptor (CAR) in hepatocarcinogenesis induced by GBE using CAR-knockout (CARKO) and wild type (WT) mice. We used the same lot of GBE that was used for the NTP study. In 1-week GBE dietary treatment, hepatocellular DNA replication was increased in WT mice but not in CARKO mice. In 4- or 13-week treatm...
Source: Food and Chemical Toxicology - June 23, 2015 Category: Food Science Authors: Maeda J, Inoue K, Ichimura R, Takahashi M, Kodama Y, Saito N, Yoshida M Tags: Food Chem Toxicol Source Type: research

Look The Way Nature Intended
Since the ’70s, at least a half-dozen Big Pharma drugs have been approved only to get shelved, because they ended up causing serious health problems. These problems have ranged from psychiatric and neurologic disorders to increased risks of heart attacks and strokes. The side effects have also included depression, vomiting, fainting, headaches, high blood pressure and liver damage. The truth is, reliable weight loss shouldn’t involve risking your life. I have successfully helped thousands of people lose weight with safe and natural herbs and supplements for decades – and I still do. Today, I’m going to show you how...
Source: Al Sears, MD Natural Remedies - June 22, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Nutrition Weight Loss diet FDA nutrients Source Type: news

CD47 blockade inhibits tumor progression human osteosarcoma in xenograft models.
In conclusion, our findings demonstrate that CD47 is a critical regulator in the metastasis of osteosarcoma and suggest that targeted inhibition of this antigen by anti-CD47 may be a novel immunotherapeutic approach in the management of this tumor. PMID: 26093091 [PubMed - as supplied by publisher] (Source: Oncotarget)
Source: Oncotarget - June 22, 2015 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Brain Food for Alzheimer-Free Ageing: Focus on Herbal Medicines.
Authors: Hügel HM Abstract Healthy brain aging and the problems of dementia and Alzheimer's disease (AD) are a global concern. Beyond 60 years of age, most, if not everyone, will experience a decline in cognitive skills, memory capacity and changes in brain structure. Longevity eventually leads to an accumulation of amyloid plaques and/or tau tangles, including some vascular dementia damage. Therefore, lifestyle choices are paramount to leading either a brain-derived or a brain-deprived life. The focus of this review is to critically examine the evidence, impact, influence and mechanisms of natural products as che...
Source: Advances in Experimental Medicine and Biology - June 22, 2015 Category: Research Tags: Adv Exp Med Biol Source Type: research

Non-pharmacological approaches for pain relief during labour can improve maternal satisfaction with childbirth and reduce obstetric interventions
Commentary on: Chaillet N, Belaid L, Crochetière C, et al. Non-pharmacological approaches for pain management during labour compared with usual care: a meta-analysis. Birth 2014:41;122–37. Implications for practice and research Most non-pharmacological methods of pain management are non-invasive and appear to provide benefits, and are safe for the mother and baby. In future trials, usual care needs to be more clearly defined and relevant outcomes such as measures of pain need to be assessed. Caregivers need to gain expertise in the use of non-pharmacological pain relief techniques so that they can be better in...
Source: Evidence-Based Nursing - June 22, 2015 Category: Nursing Authors: Jones, L. V. Tags: Midwifery, Drugs: CNS (not psychiatric), Pain (neurology), Contraception, Drugs: obstetrics and gynaecology, Pregnancy, Reproductive medicine, Hospice, Pain (palliative care), Complementary medicine, Resuscitation Source Type: research

A fortified follow-up formula for 3-4-year-olds reduces episodes of acute respiratory infection and antibiotic use compared with cow's milk
Commentary on: Li F, Jin X, Liu B, et al.. Follow-up formula consumption in 3- to 4-year-olds and respiratory infections: an RCT. Pediatrics 2014;133:e1533–40. Implications for practice and research Follow-up formula enriched with prebiotic components and yeast β-glucan might decrease the incidence and duration of respiratory tract infections in childhood. It is unclear which specific additive of the follow-up formula or the role of other dietary habits has the most beneficial effect in relation to the incidence of respiratory tract infections. Further studies are needed to improve understanding of the role of a...
Source: Evidence-Based Nursing - June 22, 2015 Category: Nursing Authors: den Dekker, H. T., Duijts, L. Tags: Diarrhoea, Child health, Immunology (including allergy), Drugs: infectious diseases, TB and other respiratory infections, Childhood nutrition, Diet, Vitamins and supplements, Reproductive medicine, Child health, Infant nutrition (including breastfeeding) Source Type: research

The immunoregulatory effects of Chinese herbal medicine on the maturation and function of dendritic cells
Conclusion This review provides useful information for understanding the mechanism of CHM on the treatment of diseases, which facilitates to improve the efficacy of CHM. Based on the immunoregulatory effects of CHM on DCs, it indicated that some CHM and its components could be use to develop adjuvant to enhance antigen-specific immune responses or tolerogenic adjuvant to generate antigen-specific immune tolerance. Graphical abstract Highlights CHM regulates the immune responses through modulating the maturation and function of DCs (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 22, 2015 Category: Drugs & Pharmacology Source Type: research

Medicinal uses, phytochemistry and pharmacology of the genus Dictamnus (Rutaceae)
Conclusion In this review, we summarized the chemical constituents, pharmacology, quality control and toxicology of the species from genus Dictamnus. Phytochemical investigations indicated that quinoline alkaloids and limonoids were the major bioactive components with potential cytotoxic, neuroprotective, anti-inflammatory, antimicrobial, anti-platelet-aggregation and vascular relaxing activities. These two kinds of compounds have attracted great interests in the past few years and may have great potential to be new drug lead compounds. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 22, 2015 Category: Drugs & Pharmacology Source Type: research

Mori Fructus improves cognitive and neuronal dysfunction induced by beta-amyloid toxicity through the GSK-3β pathway in vitro and in vivo
Conclusions These results indicate that ME protects cognition and neurons in AD-like models induced by Aβ via reduction of tau phosphorylation and apoptosis through GSK-3β inactivation. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 22, 2015 Category: Drugs & Pharmacology Source Type: research

Medicinal plants of the Kamiesberg, Namaqualand, South Africa
Conclusion The results showed that the Kamiesberg is an important focal point of Khoisan (Nama) traditional knowledge but that the medicinal plants have not yet been systematically recorded in the scientific literature. There are numerous new use records and new species records that are in need of scientific study. Comparative data is now available for broader comparisons of the pattern of Khoisan plants use in southern Africa and the study represents another step towards a complete synthesis of Cape Herbal Medicine. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 22, 2015 Category: Drugs & Pharmacology Source Type: research

Prescription patterns of Chinese herbal products for patients with uterine fibroid in Taiwan: A nationwide population-based study
Conclusions Our study identified the characteristics and prescription patterns of TCM for patients with uterine fibroid in Taiwan. Further basic mechanistic studies and clinical trials are needed to confirm the therapeutic effects and mechanisms. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 22, 2015 Category: Drugs & Pharmacology Source Type: research

Herbal composition Gambigyeongsinhwan (4) from curcuma longa, Alnus japonica, and Massa Medicata Fermentata inhibits lipid accumulation in 3T3-L1 cells and regulates obesity in Otsuka long-Evans Tokushima fatty rats
Conclusions These results demonstrate that GGH(4) has an antiobesity effects through the inhibition of adipocyte lipid accumulation, and this process may be mediated in part through adipose PPARα activation. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 22, 2015 Category: Drugs & Pharmacology Source Type: research

Sulphur alters NFκB-p300 cross-talk in favour of p53-p300 to induce apoptosis in non-small cell lung carcinoma.
Abstract Adverse side effects of chemotherapy during cancer treatment have shifted considerable focus towards therapies that are not only targeted but are also devoid of toxic side effects. We evaluated the antitumorigenic activity of sulphur, and delineated the molecular mechanisms underlying sulphur-induced apoptosis in non-small cell lung carcinoma (NSCLC) cells. A search for the underlying mechanism revealed that the choice between the two cellular processes, NFκBp65-mediated survival and p53-mediated apoptosis, was decided by the competition for a limited pool of transcriptional coactivator protein p300 in NS...
Source: International Journal of Oncology - June 22, 2015 Category: Cancer & Oncology Authors: Saha S, Bhattacharjee P, Guha D, Kajal K, Khan P, Chakraborty S, Mukherjee S, Paul S, Manchanda R, Khurana A, Nayak D, Chakrabarty R, Sa G, Das T Tags: Int J Oncol Source Type: research

Effects of polyphenol-rich plant products from grape or hop as feed supplements on iron, zinc and copper status in piglets.
Abstract Polyphenol-rich plant products as feed supplements have been shown to exert beneficial effects on feed efficiency in piglets. However, tannins as components of polyphenol-rich plant products are able to reduce the absorption of various trace elements. The present study investigated the effect of two polyphenol-rich dietary supplements, grape seed and grape marc meal extract (GME) and spent hops (SH), on iron (Fe), zinc (Zn) and copper (Cu) status in piglets supplied adequately with those trace elements. A trial with three groups of piglets which received a Control diet or the same diet supplemented with ei...
Source: Archives of Animal Nutrition - June 22, 2015 Category: Nutrition Authors: Fiesel A, Ehrmann M, Geßner DK, Most E, Eder K Tags: Arch Anim Nutr Source Type: research

Association of Auricular Reflective Points and Status of Type 2 Diabetes Mellitus: A Matched Case-Control Study.
Authors: Suen LK, Yeh CH, Kwan JY, Lee PH, Yeung GS, Wong EC, Lau BC, Tsang SC, Cheung AS, Yeung VT Abstract The reflexive property of the ear can cause various physical attributes to appear on the auricle in the presence of bodily disorders. The association of auricular signals (presence or absence of discoloration, marks after pressing, tenderness, and electrical resistance) and diabetes mellitus (DM) should be further investigated because auricular diagnosis is an objective, painless, and noninvasive method that provides rapid access to information. A matched case-control study on 282 subjects was conducted. Cas...
Source: Evidence-based Complementary and Alternative Medicine - June 21, 2015 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research