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Molecular Mechanisms Regulating Mammalian Aging
The Geroscience Interest Group (GSIG) cordially invites you to the seminar listed above. Dr. Finkel is Chief of the Center for Molecular Medicine in the Division of Intramural Research at the National Heart, Lung, and Blood Institute. Dr. Finkel’s lab investigates the role of cellular metabolism and oxidative stress in aging and age-related diseases. His research has included studies on oxidative homeostasis in stem cell biology, cellular senescence as a model for aging, the role of autophagy in age-related diseases, and interrogating pathways in model organisms to understand their role in mammalian aging. Dr. Finkel is ...
Source: Videocast - All Events - February 19, 2013 Category: Journals (General) Tags: Upcoming Events Source Type: video

Finding your niche: Tales of tissue stem cell biology from the Drosophila testis
Wednesday Afternoon Lecture SeriesAir date: 5/15/2013 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 28, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

The cell biology of genomes: From fundamentals to disease
Wednesday Afternoon Lecture Series, NIH Director's Lecture Air date: 4/10/2013 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 28, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Redox Biology - Redox Biology & Angiogenesis
The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is...
Source: Videocast - All Events - September 17, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Redox Biology - Signal Transduction & Redox Physiology
The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is...
Source: Videocast - All Events - September 17, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Redox Biology - Introduction & Redox Chemistry
The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is encouraged. Re...
Source: Videocast - All Events - September 17, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Redox Biology - Lecture 3: 1)Signal Transduction; 2)Redox Physiology
The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is...
Source: Videocast - All Events - September 12, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Redox Biology - Lecture 1: 1)Redox Introduction; 2)Redox Chemistry
The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is encouraged. Re...
Source: Videocast - All Events - September 12, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Redox Biology - Lecture 2: 1)Redox Biology; 2)Angiogenesis
The Redox Biology course will be held on Tuesday afternoons (except the Oct. 4 lectures) from 4:00-6:00 PM starting September 25 through November 7, 2012 on the Bethesda campus in Bldg. 50, Rooms 1227/1233. In addition, it will be videocast to the Frederick National Lab at Bldg. 549, Rm. A. Redox Biology is designed to provide an overview of general principles of nitric oxide biochemistry, cell biology, signal transduction, physiology, carcinogenesis, chemoprevention, angiogenesis, therapy, immunology and epidemiology. The participation of NIH postdoctoral and clinical fellows interested in redox biology is...
Source: Videocast - All Events - September 12, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Applications of Human Pluripotent Stem Cells - from Pain to Therapeutic Gain?
NIH CRM/SCIG Stem Cell Seminar Series (Extramural): Dr. Lorenz Studer Director, Sloan Kettering Institute for Stem Cell Biology, Department of Developmental Biology Air date: 9/4/2012 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 16, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Applications of Human Pluripotent Stem Cells – from Pain to Therapeutic Gain?
NIH CRM/SCIG Stem Cell Seminar Series (Extramural): Dr. Lorenz Studer Director, Sloan Kettering Institute for Stem Cell Biology, Department of Developmental Biology Air date: 9/4/2012 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 8, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

CC Grand Rounds: (1) Understanding the Complexities of Drug Resistance in Cancer (2) Genetic Retinopathies and Treatment Opportunities
Presented by: (1) Michael M. Gottesman, MD, Deputy Director for Intramural Research, Office of the Director, NIH and Chief, Laboratory of Cell Biology, Center for Cancer Research, NCI (2) Paul A. Sieving, MD, PhD, Director, NEI and Chief, Section on Translational Category: Clinical Center Grand RoundsAired date: 06/27/2012 (Source: Videocast - All Events)
Source: Videocast - All Events - June 27, 2012 Category: Journals (General) Tags: Past Events Source Type: video

NINDS: Making the Invisible Visible, Lecture and Panel Discussion
Discussion June 26 2:00 pm to 4:00 pm Natcher Conference Center, Balcony B (Building 45) Lecture by Rebecca Kamen, Professor of Art, Northern Virginia Community College Title: "Patterns: Discoveries Between Art and Science” Panel Discussion: “Engaging the imagination for science and art” Panelists: Antonina Roll-Mecak, Ph.D., Investigator, Cell Biology and Biophysics Unit, NINDS Kenton Swartz, Ph.D., Senior Investigator, Molecular Physiology and Biophysics Section, NINDS Joe Mindell, M.D., Ph.D., Senior Investigator, Membrane Transport Biophysics Air date: 6/26/2012 2:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - June 22, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Cell-Material Integration Research at iCeMS for Pluripotent Stem Cell Science and Technology
NIH CRM/SCIG Stem Cell Seminar Series: Cell-Material Integration Research at iCeMS forPluripotent Stem Cell Science and Technology Norio Nakatsuji Professor and Director Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Japan The iCeMS was founded as a global researchinstitute of Kyoto University in 2007 for advancement of cross-disciplinaryresearch by integration of cell biology, chemistry and physics. Our targeteddirections are (1) stem cell science and technology focusing on pluripotentstem cells (ES/iPS cells) and (2) creation of novel scientific fields of themesoscopic do...
Source: Videocast - All Events - February 28, 2012 Category: Journals (General) Tags: Upcoming Events Source Type: video

Molecular mechanisms regulating excitatory synapses
DIRECTOR'S SEMINAR SERIES Dr. Roche received her B.S. from Duke University. In 1995 she received her Ph.D. from Johns Hopkins University, where she worked with Richard Huganir studying the regulation of glutamate receptors. She then did a postdoctoral fellowship with Robert Wenthold in the NIDCD, where she investigated the cell biology of glutamate receptor transport and localization. Dr. Roche joined NINDS as an Investigator in 2001. The main focus of her laboratory is the study of neurotransmitter receptor expression and targeting to the synapse. Research Interests: Glutamate is the major excitatory neurotransmitter in...
Source: Videocast - All Events - December 9, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Epigenetics and plasticity in cardiac and intestine progenitor populations
NIH CRM/SCIG Stem Cell Seminar Series: Dr. Epstein's laboratory studies molecular mechanisms of neural crest and cardiac development, with a particular interest in applying lessons learned from developmental models to the understanding and therapy of adult diseases. One area of interest relates to the role of the Pax3 transcription factor in neural crest cells. Neural crest can differentiate into a multitude of cell types including nerve, bone, vascular smooth muscle and melanocytes. Defects in neural crest, and mutations in Pax3, can lead to common forms of congenital heart disease. We have used mouse models to elucidate...
Source: Videocast - All Events - November 17, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Translating DRiPs: The MHC Class I Pathway to Cell Biology Discoveries
Presented by: Jonathan Yewdell, MD, PhD, Laboratory of Viral Diseases; NIAID NIHCategory: ImmunologyAired date: 06/22/2011 (Source: Videocast - All Events)
Source: Videocast - All Events - June 24, 2011 Category: Journals (General) Tags: Past Events Source Type: video

Translating DRiPs: The MHC Class I Pathway to Cell Biology Discoveries
The Immunology Interest Group Air date: 6/22/2011 4:15:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - June 20, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Stem cell approaches to understanding lung injury repair and lung cancer
NCRM/SCIG Stem Cell Seminar Series: The broad interest of the Kim laboratory is to characterize the biology of stem cells in normal lung tissue and in lung disease. Carla Kim was the first person to develop a method to isolate a stem cell population from the adult murine lung, termed bronchioalveolar stem cells (BASCs), opening new avenues for understanding lung biology and disease. They hypothesize that BASCs play an important role in lung injury repair and may be the targets in some forms of lung disease that involve injured or depleted bronchiolar and alveolar cells. Her lab is currently developing transgenic mouse stra...
Source: Videocast - All Events - May 24, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Genetic and epigenetic control of pluripotent stem cell differentiation to motor neurons
NCRM/SCIG Stem Cell Seminar Series: Hynek Wichterle is an assistant professor holding a joint appointment in the Departments of Pathology and Cell Biology, Neurology, and Neuroscience at Columbia University Medical Center in New York. He received his M.S. degree (1993) from Charles University in Prague and his Ph.D. degree (2000) from The Rockefeller University in New York. He trained as a postdoctoral fellow at Columbia University, where he became Assistant Professor in 2004. His research focuses on developmental programs underlying specification of neuronal diversity in the developing spinal cord. His lab developed met...
Source: Videocast - All Events - March 17, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Frontiers in Intravital Microscopy (Day 2)
Intravital microscopy has developed into an exciting and powerful technique whose potential has not yet been fully explored. The goal of this symposium is to educate investigators within the NIH intramural community about this technique and its potential applicability to their work. The symposium will focus on the state-of-the-art of intravital microscopy in different areas of biomedical sciences such as cell biology, immunology, neuroscience, stem cells and tumor biology. The program includes two days of lectures from top scientists in the field, which is open to the NIH intramural community. John J. Condeelis (Einstein...
Source: Videocast - All Events - March 17, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Frontiers in Intravital Microscopy (Day 1)
Intravital microscopy has developed into an exciting and powerful technique whose potential has not yet been fully explored. The goal of this symposium is to educate investigators within the NIH intramural community about this technique and its potential applicability to their work. The symposium will focus on the state-of-the-art of intravital microscopy in different areas of biomedical sciences such as cell biology, immunology, neuroscience, stem cells and tumor biology. The program includes two days of lectures from top scientists in the field, which is open to the NIH intramural community. John J. Condeelis (Einstein...
Source: Videocast - All Events - March 17, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

EUS FNA of Solid Pseudopapillary Tumor
Download Video Pathology Description: A 41 year-old female presented to her primary care physician with back pain. Abdominal CT revealed a heterogeneous cystic mass in the body of the pancreas measuring 5.8 x 5.3 x 4.9 cm. Further evaluation with endoscopic ultrasound (EUS) revealed a 5cm multiseptated grossly solid cystic lesion consistent with a pseudopapillary neoplasm. After color doppler was used to rule out any overlying vessels, fine needle aspiration (FNA) was performed in the solid portion. FNA cytology aspirate was composed of small clusters of bland, ovoid eithelioid cells. Th...
Source: The Digital Atlas of Video Education - Gastroenterology - February 21, 2011 Category: Gastroenterology Authors: admin Tags: Pancreas Source Type: video

EUS FNA of Solid Pseudopapillary Tumor
A 41 year-old female presented to her primary care physician with back pain. Abdominal CT revealed a heterogeneous cystic mass in the body of the pancreas measuring 5.8 x 5.3 x 4.9 cm. Further evaluation with endoscopic ultrasound (EUS) revealed a 5cm multiseptated grossly solid cystic lesion consistent with a pseudopapillary neoplasm. After color doppler was used to rule out any overlying vessels, fine needle aspiration (FNA) was performed in the solid portion. FNA cytology aspirate was composed of small clusters of bland, ovoid eithelioid cells. The cell block showed small clusters of epithelioid cells that stained immun...
Source: The Digital Atlas of Video Education - Gastroenterology - February 21, 2011 Category: Gastroenterology Authors: David Arner, MD,, University of Virginia, Bryan Sauer, MD,, University of Virginia, Vanessa Shami, MD,, University of Virginia Source Type: video

Alternative Sources of Human Hematopoietic Progenitors
NCRM and NIH Stem Cell Interest Group lecture Dr. Bhatia is a recognized leader in Canada in the field of human hematopoietic stem cell biology and pluripotent stem cells (both embryonic and reprogrammed adult forms). Dr. Bhatia has made several important advancements in human stem cell research, particularly related to blood forming stem cells. Although stem cells can serve as sources for cellular and organ replacement in tissue damaged by trauma or genetic influences, and for disease intervention, programs focus on human cancer and using human stem cells to understand how cancer begins and how treatment may be revoluti...
Source: Videocast - All Events - February 4, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Cell biology of antigen presentation by dendritic cells
Presented by: Ira MellmanCategory: ImmunologyAired date: 01/19/2011 (Source: Videocast - All Events)
Source: Videocast - All Events - January 21, 2011 Category: Journals (General) Tags: Past Events Source Type: video

Cell biology of antigen presentation by dendritic cells
The Immunology Interest Group (IIG) organizes activities designed to promote information exchange and interactions among NIH scientists interested in the field of immunology, broadly defined. Interactions are facilitated via weekly meetings on current topics as well as an Annual Immunology Retreat. The Immunology Interest Group Air date: 1/19/2011 4:15:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 19, 2011 Category: Journals (General) Tags: Upcoming Events Source Type: video

Band Ligation Endoscopic Mucosal Resection of a Distal Esophageal Granular Cell Tumor
Download Video Pathology Radiology Description: Granular cell tumors (GCT) are relatively uncommon, but can occur through out the length of the gastrointestinal tract, particularly in the esophagus (1). Endoscopically, they appear as firm yellow nodules and can be mistaken for lipomas, carcinoid tumors and gastrointestinal stromal tumors. GCT generally behave in a benign manner, although malignant degeneration can occur about 3% of the time (2). Tumors that are less than 1 cm in size and that are confined to the superficial parts of the gastrointestinal tract, not involv...
Source: The Digital Atlas of Video Education - Gastroenterology - December 21, 2010 Category: Gastroenterology Authors: admin Tags: Esophagus Source Type: video

Band Ligation Endoscopic Mucosal Resection of a Distal Esophageal Granular Cell Tumor
Granular cell tumors (GCT) are relatively uncommon, but can occur through out the length of the gastrointestinal tract, particularly in the esophagus (1). Endoscopically, they appear as firm yellow nodules and can be mistaken for lipomas, carcinoid tumors and gastrointestinal stromal tumors. GCT generally behave in a benign manner, although malignant degeneration can occur about 3% of the time (2). Tumors that are less than 1 cm in size and that are confined to the superficial parts of the gastrointestinal tract, not involving the muscularis propria, are amenable to endoscopic management (3). Endoscopic ultrasound can b...
Source: The Digital Atlas of Video Education - Gastroenterology - December 21, 2010 Category: Gastroenterology Authors: John C. Deutsch, MD,, St. Mary's Duluth Clinic Source Type: video

EUS-guided FNA of a Solid Pseudopapillary Tumor of the Pancreas
Conclusion Our patient has been symptom free since the resection and a repeat CT abdomen did not show any evidence of recurrence over a period of 15 months. Surgery is the treatment of choice for the solid pseudopapillary tumor of the pancreas with an excellent prognosis. (Source: The Digital Atlas of Video Education - Gastroenterology)
Source: The Digital Atlas of Video Education - Gastroenterology - December 3, 2010 Category: Gastroenterology Authors: Truptesh H. Kothari, MD,, Lenox Hill Hospital, David H. Robbins, MD,, Lenox Hill Hospital, Deepak Vadada, MD,, Lenox Hill Hospital Source Type: video

Alternative Sources of Human Hematopoietic Progenitors
NCRM and NIH Stem Cell Interest Group lecture Dr. Bhatia is a recognized leader in Canada in the field of human hematopoietic stem cell biology and pluripotent stem cells (both embryonic and reprogrammed adult forms). Dr. Bhatia has made several important advancements in human stem cell research, particularly related to blood forming stem cells. Although stem cells can serve as sources for cellular and organ replacement in tissue damaged by trauma or genetic influences, and for disease intervention, programs focus on human cancer and using human stem cells to understand how cancer begins and how treatment may be revoluti...
Source: Videocast - All Events - November 9, 2010 Category: Journals (General) Tags: Upcoming Events Source Type: video

Epithelial Stem Cell and Regenerative Medicine
NCRM (NIH Center for Regenerative Medicine) Lecture Michele De Luca is Full Professor of Biochemistry, University of Modena and Reggio Emilia, and Director of the Centre for Regenerative Medicine and the Department of Stem Cells and Regenerative Medicine of the same University. He is Scientific Director of Holostem Terapie Avanzate S.r.l. Prof. De Luca was Scientific Director of the Veneto Eye Bank Foundation (2002-2007), Director of the Laboratory of Tissue Engineering at the Istituto Dermopatico dell’Immacolata, Rome (1996-2002), Deputy Head, Laboratory of Cell Differentiation, Istituto Nazionale per la Ricerca sul Ca...
Source: Videocast - All Events - October 6, 2010 Category: Journals (General) Tags: Upcoming Events Source Type: video

EUS FNA of Melanoma Metastatic to the Spleen
An 84 year old male with history of melanoma of the scalp diagnosed two years prior, was found to have a splenic lesion on abdominal CT scan. CT scan showed a round, hypoechoic lesion in the spleen as shown by the arrow. Linear EUS examination identified a 2 cm round, hypoechoic, hypovascular and heterogeneous lesion in the spleen as shown by the arrow. Arrow in the image points towards the splenic vessels surrounding this lesion. After confirming the absence of the vessels, 25 G needle was used to perform the FNA. Cytology showed giant tumor cells with enlarged nuclei. This image shows HMB 45 immunostains of the FNA cytol...
Source: The Digital Atlas of Video Education - Gastroenterology - September 17, 2010 Category: Gastroenterology Authors: Manmeet Padda, MD, Advanced Endoscopy Fellow, Yale University, Harry Aslanian, M.D., Associate Professor of Medicine, Yale University Source Type: video

Probing the Potential of Human Pluripotent Stem Cells
NCRM (NIH Center for Regenerative Medicine) Lecture Bill Lowry grew up in Seattle, WA and received his B.S. from the University of Washington in 1996. He then moved to New York to do his graduate work in signal transduction and cell biology with Xin-Yun Huang at Cornell Medical College in the fall of 1997. Bill then went across the street to work with Elaine Fuchs at the Rockefeller University in 2002 where he studied the mechanisms of quiescence and activation in stem cells of the Epidermis. In the summer of 2006 Bill joined the Department of Molecular, Cell and Developmental Biology at UCLA to explore adult stem cells ...
Source: Videocast - All Events - September 15, 2010 Category: Journals (General) Tags: Upcoming Events Source Type: video