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This page shows you the most recent publications within this specialty of the MedWorm directory.

Reflection on the teaching of Cariology in Brazil
(Source: Brazilian Oral Research)
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

The prevalence of elder abuse in the Porto Alegre metropolitan area
Abuse of the elderly is a form of violence to come to the public's attention. Dental professionals are in an ideal position to identify physical abuse. The aim of this study was to assess the prevalence of elderly abuse and analyze the database of injury reports that can be identified by dental teams. A documentary analysis study developed by the Elderly Protection Police Station of Porto Alegre, Rio Grande do Sul, was carried out. The information used came from 2,304 complaints filed at the aforementioned institution between the years of 2004 and 2006. The records of abuse are categorized as injury, neglect, mistreatment,...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Association between self-rated oral appearance and the need for dental prostheses among elderly Brazilians
We investigated the association between poor self-rated oral appearance and the need for dental prostheses among elderly Brazilians. National data from an epidemiological survey on oral health in Brazil conducted from 2002 to 2003 by the Ministry of Health (SB, Brazil) with a multistage random sample of 4,839 individuals aged 65–74 years in 250 towns were analyzed. The dependent variable was self-rated oral appearance, dichotomized into “poor” (poor∕very poor) and “good” (fair∕good∕very good). The main independent variable was the need for an upper or lower dental prosthesis. Other variables included sociod...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Effect of a cordless retraction paste on titanium surface: a topographic, chemical and biocompatibility evaluation
Good exposure of the preparation margins and haemostasis in the sulcular gingiva are necessary for accurate impressions to produce precise restorations. The use of cordless retraction paste material in implant dentistry is a relatively novel application. However, few studies have been conducted on the use of retraction pastes and their possible interaction with implant surfaces. Recent literature has described remnants on titanium implant surfaces and expressed the need for an assessment of the biocompatibility of the exposed surface (Chang et al.). This in vitro study evaluated the effect of a cordless gingival retraction...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Effect of chlorhexidine on the bond strength of a self-etch adhesive system to sound and demineralized dentin
This study evaluated the effect of a 2% chlorhexidine-based disinfectant (CHX) on the short-term resin-dentin bond strength of a self-etch adhesive system to human dentin with different mineral contents. Dentinal mineralization was tested at 4 levels (sound, and after 2, 4, or 8 days of demineralization-remineralization cycles) and disinfectant at 2 levels [deionized water (DW, negative control) and CHX]. Dentin demineralization induced by pH-cycling was characterized by cross-sectional hardness (CSH). Each dentin surface was divided into halves, one treated with DW and the other with CHX (5 minutes). Each surface was bo...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Evaluation of bone alterations in the jaws of HIV-infected menopausal women
The advent of highly active antiretroviral therapy (HAART) has caused a reduction in mortality, thus contributing to an increase in the number of women with HIVࢧAIDS who reach the climacteric period, experience decline in ovarian function, and develop complications of viral infection and HAART, which can accelerate bone loss. The aim of this study was to detect possible alterations in the jaws of HIV-infected women by panoramic radiography. The study comprised a total of 120 women above 40 years of age who were divided into the following two groups: women who are HIV positive (Group I) and women with no known HIV infecti...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Influence of disinfectant solutions on test materials used for the determination of masticatory performance
In conclusion, disinfection did not alter the reliability of the test materials for the MP calculation for up to 60 days. (Source: Brazilian Oral Research)
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Radiodensitometric and DXA analyses for the measurement of bone mineral density after systemic alendronate therapy
In conclusion, both of the methods were able to detect an increase in BMD of the proximal tibial metaphysis after alendronate therapy. (Source: Brazilian Oral Research)
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Factors contributing to the surgical retreatment of mandibular fractures
The purpose of this retrospective study was to evaluate contributing factors in patients requiring surgical retreatment of mandibular fractures. Of all the patients with mandibular fractures who were treated using internal fixation at a trauma hospital over a seven-year period, 20 patients (4.7%) required a second surgery and thus composed the “reoperated” group. The control group comprised 42 consecutive patients with mandibular fractures who were treated at the same clinic and who healed without complications. Medical charts were reviewed for gender, age, substance abuse history, dental condition, etiology, location ...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery
The objective of the study was to compare the analgesic effectiveness of dexamethasone and diclofenac sodium administered preemptively after surgical removal of third molars. Forty-four ASA (American Society of Anesthesiologists) I patients (19 men, 35 women; 16–28 years old) randomly and double-blindly received diclofenac sodium (50 mg) or dexamethasone (8 mg) or placebo 1 h before surgery. Intensity of pain, measured with a visual analog scale (VAS), was the variable studied at different postoperative times (1 h, 2 h, 3 h, 6 h, 8 h, 12 h, 48 h, 4 d and 7 d). The total amount of rescue medication...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Relationship among oral habits, orofacial function and oral health-related quality of life in children
The objective was to evaluate the relationship among oral habits, oral function and oral health-related quality of life (OHRQoL) in children. Three hundred and twenty-eight subjects (8–14 years old) were assessed for orofacial function using the Brazilian version of the Nordic Orofacial Test-Screening (NOT-S). OHRQoL was assessed using the Child Perceptions Questionnaires (Brazilian versions) for the 8–10 (CPQ8-10) and 11–14 (CPQ11-14) year age groups. The subjects were distributed into a Habit group and a Habit-free group according to domain III (Habits) of the NOT-S. Oral habits were present in 71.3% of the sample ...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Efficacy of 1.23% APF gel applications on incipient carious lesions: a double-blind randomized clinical trial
The aim of this double-blind randomized clinical trial was to evaluate the efficacy of 1.23% APF gel application on the arrest of active incipient carious lesions in children. Sixty 7- to 12-year-old children, with active incipient lesions were included in the study. Children were divided randomly into 2 groups: 1.23% APF gel and placebo gel applications. Each group received 8 weekly applications of treatment. The lesions were re-evaluated at the 4th and 8th appointments. Poisson regression analysis was used to estimate relative risks of the presence of active white spot lesions. Groups showed similar results (PR = 1.67; C...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Influence of photo-activation source on enamel demineralization around restorative materials
This study evaluated the effects of the photoactivation source and restorative material on the development of caries-like lesions on human enamel after an in vitro pH challenge. Enamel cavities were prepared in 36 blocks, which were assigned to two groups according to the restorative material: resin-modified glass ionomer (RMGI) and composite resin (CR). Samples were exposed to quartz-tungsten-halogen lamp, argon-ion laser, or light-emitting diode (n = 6). The Knoop microhardness (KHN) values of the top surface of all materials were evaluated. Restored enamel blocks were thermocycled and subjected to 10 demineralization-re...
Source: Brazilian Oral Research - May 14, 2013 Category: Dentistry Source Type: research

Apical extrusion of debris: A literature review of an inherent occurrence during root canal treatment
This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)
Source: International Endodontic Journal - May 14, 2013 Category: Dentistry Authors: J. Tanalp, T. Güngör Tags: Review Source Type: research

A randomised trial of a simplified method for complete denture fabrication: patient perception and quality
This study compared a simplified method for complete denture fabrication to a conventional protocol in terms of oral health‐related quality of life (OHRQoL), patient satisfaction and denture quality. Forty‐two edentulous patients requesting treatment with complete dentures were randomly allocated into two study groups. Group S received dentures fabricated by a simplified method and Group C received conventionally fabricated dentures. Before interventions and after three and 6 months following insertion, OHRQoL and patient satisfaction were analysed by specific instruments. A prosthodontist assessed denture quality 3 ...
Source: Journal of Oral Rehabilitation - May 14, 2013 Category: Dentistry Authors: R. R. Regis, T. R. Cunha, M. P. Della Vecchia, A. B. Ribeiro, C. H. Silva‐Lovato, R. F. de Souza Tags: Original Article Source Type: research

Evaluation of scaling and root planing effect in generalized chronic periodontitis by fractal and multifractal analysis
ConclusionIt has been shown that fractal and multifractal analysis of tissue images as a non‐invasive technique could be used to measure contrasting morphologic changes within human gingival cells and tissues and can provide detailed information for investigation of healthy and diseased gingival mucosa from patients with GCP. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - May 14, 2013 Category: Dentistry Authors: A. E. Pârvu, Ş. Ţălu, C. Crăciun, S. F. Alb Tags: Original Article Source Type: research

Fractographic analyses of all-ceramic crowns: A study of 27 clinically fractured crowns
Abstract: Objectives: The use of all-ceramic restorations has been steadily increasing in the decades since the introduction of high-strength core ceramics as an alternative to metal cores. Even with high-strength ceramic cores, the crowns are susceptible to fractures during clinical function, probably the major concern associated with all-ceramic restorations. The aim of this study was to analyze fracture features of clinically fractured crowns in order to determine crack initiation sites and crack propagation paths.Methods: Fractographic methods were used to analyze 27 all-ceramic full coverage crowns with alumina cores ...
Source: Dental Materials - May 14, 2013 Category: Materials Science Authors: Marit Øilo, Nils Roar Gjerdet Tags: Online only articles Source Type: research

The relationship between root concavities in first premolars and chronic periodontitis
ConclusionRoot concavities of the first premolars were associated with periodontal disease, and the type of interproximal alveolar bone defect. Root concavities may be important in contributing to local periodontal disease of the first premolars. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - May 14, 2013 Category: Dentistry Authors: H. Zhao, H. Wang, Y. Pan, C. Pan, X. Jin Tags: Original Article Source Type: research

Assessment of the quality of reporting in abstracts of systematic reviews with meta‐analyses in periodontology and implant dentistry
ConclusionAbstracts of SRs with meta‐analyses in periodontology and implant dentistry currently have no uniform standard of reporting, which may hinder readers’ understanding of study outcomes. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - May 14, 2013 Category: Dentistry Authors: C. M. Faggion, J. Liu, F. Huda, M. Atieh Tags: Review Article Source Type: research

No evidence of triclosan‐resistant bacteria following long‐term use of triclosan‐containing toothpaste
ConclusionThe use of TCS‐containing toothpaste did not appear to lead to an increase in MIC of TCS of oral bacterial isolates. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - May 14, 2013 Category: Dentistry Authors: M. P. Cullinan, P. S. Bird, N. C. K. Heng, M. J. West, G. J. Seymour Tags: Original Article Source Type: research

Effectiveness of metronidazole as an adjunct to scaling and root planing in the treatment of chronic periodontitis: a systematic review and meta‐analysis
ConclusionThe meta‐analysis results seem to support the effectiveness of adjunctive MET with SRP compared to SRP alone. However, given the low number of included studies and limitations of meta‐analysis, future studies are needed to confirm these results. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - May 14, 2013 Category: Dentistry Authors: F. Sgolastra, M. Severino, A. Petrucci, R. Gatto, A. Monaco Tags: Review Article Source Type: research

Developmental defects of enamel in primary teeth and association with early life course events: a study of 6--36 month old children in Manyara, Tanzania
In northern Tanzania, low birth weight children have a greater prevalence of developmental enamel defects at ages 6-36 months, providing new insight into the risk factors for dental problems in early childhood (Source: BMC Oral Health - Latest articles)
Source: BMC Oral Health - Latest articles - May 14, 2013 Category: Dentistry Authors: Ray MasumoAsgeir BårdsenAnne Åstrøm Source Type: research

Dental caries prevalence, oral health knowledge and practice among indigenous Chepang school children of Nepal.
Conclusions: Caries prevalence of 5--6 --year- old Chepang school children is above the recommended target set by FDI/WHO. The study reported 31% schoolchildren aged 8-16-year old suffered oral pain and decayed component constituted almost the entire dmft/DMFT index. The brushing habit was reportedly low with only 24% of the children brushing twice daily. A nationwide scientifically proven, cost effective school based interventions is needed for prevention and control of caries in schoolchildren in Nepal. (Source: BMC Oral Health - Latest articles)
Source: BMC Oral Health - Latest articles - May 14, 2013 Category: Dentistry Authors: Lonim Prasai DixitAjay ShakyaManash ShresthaAyush Shrestha Source Type: research

A rare presentation of multiple primary squamous cell carcinoma of the tongue in a patient with recurrent hepatitis C infection
ABSTRACT Hepatitis C virus (HCV) infection has been implicated as a risk factor for development of oral squamous cell carcinoma (SCC). Multiple primary sites of oral SCC associated with HCV infection occurs infrequently. This case report describes a rare presentation of multiple primary SCCs of the tongue in a patient with recurrent HCV cirrhosis status post liver transplant that required interdisciplinary medical and surgical management. It is important for oral health care providers to understand the local and systemic implications of HCV infection and perform routine clinical examinations to monitor for development of o...
Source: Special Care in Dentistry - May 14, 2013 Category: Dentistry Authors: Eric T. Stoopler, Ying Wai Sia, Ara A. Chalian, Bert W. O'Malley, Faizan Alawi Tags: Case History Report Source Type: research

Temporomandibular disorder in a patient with pseudoxanthoma elasticum: a case report and review
We present a case of a 46‐year‐old female with PXE diagnosed with temporomandibular disorder (TMD). To our knowledge, this is the first report of a patient with TMD coexisting with PXE in the scientific literature. (Source: Special Care in Dentistry)
Source: Special Care in Dentistry - May 14, 2013 Category: Dentistry Authors: Christine Nadeau, Arthur S. Kuperstein, Muralidhar Mupparapu, Eric T. Stoopler Tags: Case History Report Source Type: research

Differentiation of human dental stem cells reveals a role for microRNA‐218
ConclusionThese data reveal a miRNA‐regulated pathway for the differentiation of human DSCs and a select network of human miRNAs that control DSC osteogenic differentiation. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - May 13, 2013 Category: Dentistry Authors: I. Gay, A. Cavender, D. Peto, Z. Sun, A. Speer, H. Cao, B. A. Amendt Tags: Original Article Source Type: research

Commentary to Manfredini et al. J Oral Rehabil. 2012;39:463–71
(Source: Journal of Oral Rehabilitation)
Source: Journal of Oral Rehabilitation - May 13, 2013 Category: Dentistry Authors: G. M. Tartaglia, C. M. Felicio, C. Sforza Tags: Commentary Source Type: research

Correlation of previous experience, patient expectation and the number of post‐delivery adjustments of complete dentures with patient satisfaction in a Brazilian population
The objective of this study was to verify possible correlations between previous experience with dentures, patient expectation and the number of post‐delivery adjustments with patient satisfaction after treatment. One hundred patients (mean age 61·9 ± 10·3) rated their previous experiences with complete dentures and their expectations before and satisfaction after treatment on a visual analogue scale (VAS) using scores from 0 (worst results) to 10 (best results). The number of post‐delivery adjustments and other patient‐related clinical variables was also noted. Patient expectation scores were higher than previo...
Source: Journal of Oral Rehabilitation - May 12, 2013 Category: Dentistry Authors: M. G. Gaspar, M. B. F. Dos Santos, J. F. F. Dos Santos, L. Marchini Tags: Original Article Source Type: research

In vitro chipping behaviour of all‐ceramic crowns with a zirconia framework and feldspathic veneering: comparison of CAD/CAM‐produced veneer with manually layered veneer
Summary The purpose of this in vitro study was to assess the breaking load of zirconia‐based crowns veneered with either CAD/CAM‐produced or manually layered feldspathic ceramic. Thirty‐two identical zirconia frameworks (Sirona inCoris ZI, mono L F1), 0·6 mm thick with an anatomically shaped occlusal area, were constructed (Sirona inLab 3.80). Sixteen of the crowns were then veneered by the use of CAD/CAM‐fabricated feldspathic ceramic (CEREC Bloc, Sirona) and 16 by the use of hand‐layered ceramic. The CAD/CAM‐manufactured veneer was attached to the frameworks by the use of Panavia 2.0 (Kuraray). Half of the ...
Source: Journal of Oral Rehabilitation - May 11, 2013 Category: Dentistry Authors: M. Schmitter, D. Mueller, S. Rues Tags: Original Article Source Type: research

Profiling biomarkers in gingival crevicular fluid using multiplex bead immunoassay
Conclusion: IL-1β levels in GCF correlate with the PDs, BOP and the presence of P. gingivalis in subgingival plaque. Multiplex bead assays can be useful in GCF studies. These findings can help in identifying new diagnostic methods in the diagnosis of periodontal disease. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Yasuko Shimada, Koichi Tabeta, Noriko Sugita, Hiromasa Yoshie Tags: Periodontology Source Type: research

Toll-like receptor activation and mechanical force stimulation promote the secretion of matrix metalloproteinases 1, 3 and 10 of human periodontal fibroblasts via p38, JNK and NF-kB
Abstract: Matrix metalloproteinases (MMPs) are known to play a key role during orthodontic treatment leading to periodontal remodelling and tooth movement. MMPs may be induced by mechanical forces. However, the role played by toll-like receptors (TLRs) in modulating the effects of the mechanical force on periodontal fibroblasts is not known. To investigate the interaction between mechanical force and TLR stimulation, primary cultures of human periodontal fibroblasts were submitted to centrifugation in the presence of LPS and Pam3Cys, which are known TLR-4 and TLR-2 ligands, respectively. The expression of MMP-1, -2, -3, -8...
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Rodolfo Assis Lisboa, Marcus Vinícius Andrade, José Renan Cunha-Melo Tags: Periodontology Source Type: research

Dental caries and chemical analyses in reconstruction of diet, health and hygienic behaviour in the Middle Euphrates valley (Syria)
Discussion: These data suggest a similar socio-economic status during the Late Roman and Islamic periods. The diet of the population living in the Late Roman and Islamic periods contained a larger number of products containing strontium than calcium. In the modern population these proportions have been reversed. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Jacek Tomczyk, Krzysztof Szostek, Iulian Komarnitki, Hanna Mańkowska-Pliszka, Marta Zalewska Tags: Paleodontology Source Type: research

Evaluation of the effects of transient or continuous PTH administration to odontoblast-like cells
Abstract: Parathyroid hormone participates in the metabolism of mineralized tissue. Its role in the formation of dentine is, as yet, incompletely understood. In the present study we analyzed the effect of transient (1 and 24-h/cycle) or continuous hPTH (1–34) treatment in odontoblast-like cells (MDPC-23) to the following parameters: mineral deposition detected by alizarin red, mRNA expression of the type I collagen (COL1), alkaline phosphatase (ALP), biglycan (BGN), matrix metalloproteinase 2 (MMP-2) and dentine sialophosphoprotein (DSPP) quantified by qRT-PCR. MMP-2 and ALP activities were quantified by zymography and c...
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Gustavo Narvaes Guimarães, Rafael Nóbrega Stipp, Thaisângela Lopes Rodrigues, Ana Paula de Souza, Sergio Roberto Peres Line, Marcelo Rocha Marques Tags: Bone Biology Source Type: research

TGF-β1 and BMP-4 carried by liposomes enhance the healing process in alveolar bone
Conclusion: The present study indicates growth factors carried by liposomes, either in isolated or associated forms, as successful enhancers of the healing process in rat tooth sockets. We also conclude that the expression of fibronectin and collagen type III increases during the early phases of bone repair. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Cynthia Lopes Ferreira, Fernando Antônio Mauad de Abreu, Gerluza Aparecida Borges Silva, Frank Ferreira Silveira, Luana Beatriz Araújo Barreto, Tony de Paiva Paulino, Melissa Nunes Miziara, José Bento Alves Tags: Bone Biology Source Type: research

Factors associated with specific clinical forms of oral candidiasis in HIV-infected Brazilian adults
Conclusion: The data indicates that the odds of having all clinical forms of OC are higher in HIV-infected adults not receiving HAART. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Lucio Souza Gonçalves, Arley Silva, Sônia Maria Soares Ferreira, Celso Oliveira Sousa, Tatiana Vasconcellos Fontes, Mario Vianna Vettore, Sandra Regina Torres Tags: Mucosal Biology Source Type: research

Bioinformatics and systems biology analysis of genes network involved in OLP (Oral Lichen Planus) pathogenesis
Conclusions: Even with the limitations of any ab initio analysis, this study can suggest targeted experimentation, focused on the leader genes and therefore simpler to be analysed than mass scale molecular genomics. Moreover, it may suggest new potential risk factors and therapeutic targets. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: B. Orlando, N. Bragazzi, C. Nicolini Tags: Mucosal Biology Source Type: research

Association between occlusal curvature and masticatory movements with different test foods in human young adults with permanent dentitions
This study investigated the association between occlusal curvature and mandibular movements while chewing a variety of food items.Design: Forty-six young adults with complete dentitions (mean age, 25.0 years) participated in the study. Sphere radius of occlusal curvature was determined by a three-dimensional analysis of the mandibular arch based on the Broadrick flag method. Mandibular movements during unilateral chewing of six test food items (chewing gum, cheese, kamaboko, boiled beef, gummy jelly and raw carrot) until the subjects felt ready to swallow were recorded using a six-degrees-of-freedom mandibular movement rec...
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Kenji Fueki, Eiko Yoshida, Kota Okano, Yoshimasa Igarashi Tags: Mastication Source Type: research

Identification of disulphide stress–responsive extracytoplasmic function sigma factors in Rothia mucilaginosa
Summary: Rothia mucilaginosa is known as a member of commensal bacterial flora in the oral cavity and has received attention as a potential opportunistic pathogen. We previously determined the genomic sequence of R. mucilaginosa DY-18, a clinical strain with biofilm-like structures isolated from an infected root canal of a tooth with persistent apical periodontitis. We found that the DY-18 genome had only two sigma factor genes that encoded the primary and extracytoplasmic function (ECF) sigma factors. Genomic analysis on the available database of R. mucilaginosa ATCC 25296 (a type strain for R. mucilaginosa) revealed that...
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Takayuki Nambu, Kazuyoshi Yamane, Takeshi Yamanaka, Chiho Mashimo, Hugo Maruyama, Masahiro Yoshida, Hiroyuki Hayashi, Kai-Poon Leung, Hisanori Fukushima Tags: Oral Microbiology Source Type: research

Bone morphogenetic protein 6 stimulates mineralization in human dental follicle cells without dexamethasone
Conclusion: These findings suggest that hDFCs can differentiate to osteogenic lineage cells osteogenic induction medium without DEX, and BMP6 is a key gene in the osteogenic differentiation of hDFCs, and has therapeutic utility for bone regeneration and bone research. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Kosuke Takahashi, Naomi Ogura, Haruna Aonuma, Ko Ito, Daisuke Ishigami, Yoshikazu Kamino, Toshirou Kondoh Tags: Stem cells Source Type: research

Comparison of the differentiation potential of neural crest derived progenitor cells from apical papilla (dNC-PCs) and stem cells from exfoliated deciduous teeth (SHED) into mineralising cells
Conclusion: Our results suggest that dNC-PCs are precursors for primary odontoblasts, whereas SHED differentiate into replacement odontoblasts. These different odontogenic differentiation potentials of dNC-PCs and SHED have to be considered for cellular therapies and tissue engineering approaches in the future. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Martin Gosau, Werner Götz, Oliver Felthaus, Tobias Ettl, Andreas Jäger, Christian Morsczeck Tags: Stem cells Source Type: research

Compressive stress induced the up-regulation of M-CSF, RANKL, TNF-α expression and the down-regulation of OPG expression in PDL cells via the integrin-FAK pathway
Conclusions: Results of this study indicate that the integrin-FAK pathway regulates compressive stress-induced expression of M-CSF, TNF-α, RANKL and OPG and suggests that the integrin-FAK complex acts as a mechanoreceptor in PDL cells. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Soo-Jung Kim, Ki-Ho Park, Young-Guk Park, Suk-Won Lee, Yoon-Goo Kang Tags: Periodontology Source Type: research

The effects of non-surgical periodontal therapy on oxidant and anti-oxidant status in smokers with chronic periodontitis
Abstract: Aim: The aim of this study was to determine the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) and serum oxidant–antioxidant levels in smoking and non-smoking patients with chronic periodontitis.Methods: Twenty-nine patients with chronic periodontitis (15 smokers (CP-S) and 14 non-smokers (CP-NS)) and 20 periodontally healthy subjects (10 smokers (H-S) and 10 non-smokers (H-NS)) totalling 49 subjects were included in this study. GCF was collected from at least two pre-selected sites (one moderate and one deep pocket) in patients with CP. In the healthy group, GCF samples were co...
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Aysun Akpinar, Hulya Toker, Hakan Ozdemir, Vildan Bostanci, Huseyin Aydin Tags: Periodontology Source Type: research

Editorial board
(Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Source Type: research

Ascorbic acid and its pro-oxidant activity as a therapy for tumours of oral cavity – A systematic review
Conclusion: The results of our systematic review show that the pro-oxidant activity of pharmacologic ascorbic acid is a part of its dose-dependent bimodal activity and is a result of the proposed Fenton mechanism. In vitro, animal and ex vivo studies of pharmacologic ascorbic acid (AA) have yielded meritorious results proving vitamin C as an effective cytotoxic agent against oral neoplastic cells with potentially no harming effects on normal cells. However, a shortage of clinical trials and in vivo human studies pertaining to evaluation of anti-tumour activity of vitamin C in tumours of oral cavity remains a lacuna in conc...
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Manisha Chandini Putchala, Pratibha Ramani, Herald J. Sherlin, Priya Premkumar, Anuja Natesan Tags: Review Source Type: research

The effect of dentinal fluid flow during loading in various directions—Simulation of fluid–structure interaction
Conclusion: This study suggests that experiments to investigate the relationship between loading in various directions and dental pain should avoid measuring the bulk pulpal fluid flow from radicular pulp, but rather should measure the dentinal fluid flow in the dentinal tubules or coronal pulp. The FSI analysis used here could provide a powerful tool for investigating problems with coupled solid and fluid structures in dental biomechanics. (Source: Archives of Oral Biology)
Source: Archives of Oral Biology - May 10, 2013 Category: Dentistry Authors: Kuo-Chih Su, Chih-Han Chang, Shu-Fen Chuang, Eddie Yin-Kwee Ng Tags: Tooth Biology Source Type: research