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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 9.

Ac45 silencing mediated by AAV-sh-Ac45-RNAi prevents both bone loss and inflammation caused by periodontitis.
CONCLUSIONS: Local AAV-sh-Ac45 gene therapy efficiently protects against periodontal tissue damage and bone erosion through both inhibition of osteoclast function and attenuating inflammation, and may represent a powerful new treatment strategy for periodontitis. This article is protected by copyright. All rights reserved. PMID: 25952706 [PubMed - as supplied by publisher] (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - May 7, 2015 Category: Dentistry Authors: Zhu Z, Chen W, Hao L, Zhu G, Lu Y, Li S, Wang L, Li YP Tags: J Clin Periodontol Source Type: research

Immediate Loading of Dental Implants in Edentulous Mandibles by Use of Locator® Attachments or Dolder® Bars: Two‐Year Results from a Prospective Randomized Clinical Study
ConclusionWithin the limitations of this study, results from immediate loading of two implants in the edentulous mandible with either Locator or bar attachments hardly differed. Prosthetic complications and aftercare measures in the Locator group were frequent but easy to handle. Ease of repair and cleaning, in particular, might be reasons for choosing the single‐attachment system. (Source: Clinical Implant Dentistry and Related Research)
Source: Clinical Implant Dentistry and Related Research - May 7, 2015 Category: Dentistry Authors: Stefanie Kappel, Nikolaos Nikitas Giannakopoulos, Lydia Eberhard, Peter Rammelsberg, Constantin Eiffler Tags: Original Article Source Type: research

Effect of Ultrasonic Activation of Irrigants on Smear Layer Removal
The objective of this study was to evaluate the efficacy of passive ultrasonic irrigation (PUI) with 17% EDTA and 1% NaOCl solutions on smear layer removal. (Source: Journal of Endodontics)
Source: Journal of Endodontics - May 7, 2015 Category: Dentistry Authors: Tamer F. Schmidt, Cleonice S. Teixeira, Mara C.S. Felippe, Wilson T. Felippe, David H. Pashley, Eduardo A. Bortoluzzi Tags: Basic Research Source Type: research

The European Academy of Paediatric Dentistry and Molar Incisor Hypomineralisation
(Source: European Archives of Paediatric Dentistry)
Source: European Archives of Paediatric Dentistry - May 6, 2015 Category: Dentistry Source Type: research

Review of current concepts of revascularization/revitalization
Abstract This review focuses on the current concepts on revascularization/revitalization therapy. Revascularization/revitalization procedures performed under current protocols have reportedly achieved successful clinical and radiographical outcomes for immature permanent teeth with non‐vital pulps; however, randomized prospective studies are needed to develop evidence‐based methodologies for regenerative endodontic treatment. (Source: Dental Traumatology)
Source: Dental Traumatology - May 6, 2015 Category: Dentistry Authors: Tuğba Bezgin, Hayriye Sönmez Tags: Review Source Type: research

Effect of intentional abutment disconnection on the micro‐movements of the implant–abutment assembly: a 3D digital image correlation analysis
ConclusionMicro‐movements were higher for the group submitted to intentional disconnection and reconnection of the abutment, particularly under average bite forces. (Source: Clinical Oral Implants Research)
Source: Clinical Oral Implants Research - May 6, 2015 Category: Dentistry Authors: Ana Messias, Salomão Rocha, Nuno Calha, Maria Augusta Neto, Pedro Nicolau, Fernando Guerra Tags: Original Article Source Type: research

Dental, skeletal asymmetries and functional characteristics in Class II subdivision malocclusions
This study was a cross‐sectional investigation of the characteristics of Angle Class II subdivision malocclusion, including dental, skeletal and functional factors, by comparison of the subdivision group and the normal occlusion group. The evaluations of dental and skeletal asymmetries of both groups were carried out by cone‐beam computed tomography (CBCT) and analysis of dental casts. The functional deviations were evaluated by cast mounting and measuring. In the subdivision group, the asymmetric position of the glenoid fossa was found to be the most significant skeletal asymmetry. No dentoalveolar asymmetry was found...
Source: Journal of Oral Rehabilitation - May 6, 2015 Category: Dentistry Authors: J. Li, Y. He, Y. Wang, T. Chen, Y. Xu, X. Xu, H. Zeng, J. Feng, Z. Xiang, C. Xue, X. Han, D. Bai Tags: Original Article Source Type: research

Five HighPointe nurses among healthcare workers disciplined by state
Five nurses formerly employed at HighPointe on Michigan nursing home were among eight local nurses and a dentist disciplined by state officials in March and April following reviews by the state Board of Regents. The disciplinary actions come a year after the State Attorney General brought charges against 17 health workers at the Kaleida Health facility of endangering the welfare of an incompetent or physically disabled person and falsifying business records. The five licensed practical nurses received… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - May 6, 2015 Category: Biotechnology Authors: Tracey Drury Source Type: news

Compiling a 'dentist's handbook' for penis worms
(University of Cambridge) A new study of teeth belonging to a particularly phallic-looking creature has led to the compilation of a prehistoric 'dentist's handbook' which may aid in the identification of previously unrecognized specimens from the Cambrian period, 500 million years ago. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 6, 2015 Category: Biology Source Type: news

Clinical Pathologic Conference Case 1: A Multilocular Radiolucency in the Posterior Mandible
A 22-year-old white female presented to the general dentist with swelling in the right mandible and submandibular area. Clinical examination confirmed expansion of the right mandible. Panoramic radiographic examination revealed a large, well-circumscribed multilocular radiolucency distal to the canine within the body of the mandible (Figure 1). An incision and drainage procedure was performed but was unsuccessful. Aspiration of the lesion also failed to yield output. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - May 6, 2015 Category: ENT & OMF Authors: Colin Eliot, Harvey P. Kessler Tags: Oral and maxillofacial pathology Source Type: research

Clinical Pathologic Conference Case 3: A 15-Year-Old Male With a Radiolucent Jaw Lesion
A 15-year-old male presented to his dentist with a well-circumscribed radiolucent lesion in the right posterior mandible (Figures 1 and 2). His medical history was noncontributory, and it was reported that the patient was quite active in sports with a particular interest in karate. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - May 6, 2015 Category: ENT & OMF Authors: D. White, L.A. Franklin Tags: Oral and maxillofacial pathology Source Type: research

Dimensional soft tissue changes following soft tissue grafting in conjunction with implant placement or around present dental implants: a systematic review
ConclusionsThe present systematic review discovered that connective tissue grafts enhanced keratinised mucosa width and soft tissue thickness for an observation period of up to 48 months. However, some shrinkage may occur, resulting in decreases in soft tissue, mostly for the first three months. Further investigations using accurate evaluation methods need to be done to evaluate the appropriate time for grafting. (Source: Clinical Oral Implants Research)
Source: Clinical Oral Implants Research - May 6, 2015 Category: Dentistry Authors: Lukas Poskevicius, Antanas Sidlauskas, Pablo Galindo‐Moreno, Gintaras Juodzbalys Tags: Review Source Type: research

Clinical performance of two‐piece zirconia implants in the posterior mandible and maxilla: a prospective cohort study over 2 years
ConclusionWithin the limitations of a prospective cohort study, it was concluded that this two‐piece zirconium implant/fibreglass abutment system can be successfully used in the clinical indication investigated. (Source: Clinical Oral Implants Research)
Source: Clinical Oral Implants Research - May 6, 2015 Category: Dentistry Authors: Jürgen Becker, Gordon John, Kathrin Becker, Saskia Mainusch, Gabriele Diedrichs, Frank Schwarz Tags: Original Article Source Type: research

Chemokine RANTES/CCL5 as an unknown link between wound healing in the jawbone and systemic disease: is prediction and tailored treatments in the horizon?
Conclusions As RANTES is discussed in the literature as a possible contributor to inflammatory diseases, and though it might have oncogenic effects, we hypothesize that FDOJ in areas of improper and incomplete wound healing in the jawbone might act as hyperactivated signaling pathways, while serving as an unknown source of “silent inflammation”. Because of the wide range of RANTES in immune diseases, treating FDOJ can cover many potential prediction or prognosis of individual outcomes. (Source: EPMA Journal)
Source: EPMA Journal - May 6, 2015 Category: Global & Universal Source Type: research

The origin of endodontic Enterococcus faecalis explored by comparison of virulence factor patterns and antibiotic resistance to that of isolates from stool samples, blood cultures and food
ConclusionsEvidence for a food‐borne transmission, explaining the high reported prevalence of E. faecalis in root filled teeth, could not be determined based on similarities in virulence factor patterns and antibiotic susceptibility. The only linkage between isolates from food and root canals consisted of a shared common combination of the genes gelE, efaA and ace. The high occurrence of putative virulence traits in food isolates question the safety of E. faecalis in food products.This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)
Source: International Endodontic Journal - May 6, 2015 Category: Dentistry Authors: R. Vidana, MU. Rashid, V. Özenci, A. Weintraub, B. Lund Tags: Original Scientific Article Source Type: research

Prescribing errors in antibiotic prophylaxis by dentists in a large Brazilian city
Publication date: Available online 29 April 2015 Source:American Journal of Infection Control Author(s): Sheila Monteiro Lisboa , Maria Auxiliadora Parreiras Martins , Lia Silva de Castilho , Maria Elisa de Souza e Silva , Mauro Henrique Nogueira Guimarães Abreu Prescribing errors may contribute to antibiotic resistance and other drug-related problems. To investigate the quality of prescriptions involving antibiotic prophylaxis by dentists in a large Brazilian city, 366 dental prescriptions were randomly selected from 31,105. A prophylaxis indication represented 24.9% of the prescriptions, and only 12 (13.2%; 95% confid...
Source: American Journal of Infection Control - May 6, 2015 Category: Infectious Diseases Source Type: research

Quantitative evaluation of apically extruded debris with Twisted File Adaptive instruments in straight root canals: reciprocation with different angles, adaptive motion, and continuous rotation
ConclusionMovement kinematics affected the amount of apically extruded debris when using Twisted File Adaptive instruments.This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)
Source: International Endodontic Journal - May 6, 2015 Category: Dentistry Authors: E Karataş, H Arslan, D Ö Kırıcı, M Alsancak, İ D Çapar Tags: Original Scientific Article Source Type: research

Effect of final irrigation protocols on push‐out bond strength of an epoxy resin root canal sealer to dentin
Abstract The purpose of the present study was to evaluate the effect of different final irrigation protocols on push‐out bond strength of an epoxy resin root canal sealer to dentin. Eighty single‐rooted anterior teeth were used. The root canals were partially prepared using a rotary system and the final diameter was standardised using a #5 Gates‐Glidden drill prior to the push‐out bond test. During chemomechanical preparation, 5.25% NaOCl or 2% CHX gel was used. For smear layer removal, 17% ethylenediaminetetraacetic acid (EDTA) or QMix 2 in 1 was applied for 3 min. As final irrigant, 1 mL of NaOCl, CHX solutio...
Source: Australian Endodontic Journal - May 6, 2015 Category: Dentistry Authors: Fernanda Leal, Renata Antoun Simão, Sandra Rivera Fidel, Rivail Antônio Sérgio Fidel, Maíra Prado Tags: Original Research Source Type: research

Impact of lateral occlusion schemes: A systematic review
Conclusion Although there are immediate differences between the different lateral occlusion schemes, patients have the capability to successfully adapt to CGO or GFO. (Source: The Journal of Prosthetic Dentistry)
Source: The Journal of Prosthetic Dentistry - May 6, 2015 Category: Dentistry Source Type: research

Issue information
(Source: Special Care in Dentistry)
Source: Special Care in Dentistry - May 6, 2015 Category: Dentistry Tags: Issue information Source Type: research

Remembering Dr. Carlos Salinas
(Source: Special Care in Dentistry)
Source: Special Care in Dentistry - May 6, 2015 Category: Dentistry Authors: Maureen Munnelly Perry Tags: MEMORIAL Source Type: research

Changes of Root Length and Root-to-Crown Ratio after Apical Surgery: An Analysis by Using Cone-beam Computed Tomography
Apical surgery is an important treatment option for teeth with post-treatment periodontitis. Although apical surgery involves root-end resection, no morphometric data are yet available about root-end resection and its impact on the root-to-crown ratio (RCR). The present study assessed the length of apicectomy and calculated the loss of root length and changes of RCR after apical surgery. (Source: Journal of Endodontics)
Source: Journal of Endodontics - May 6, 2015 Category: Dentistry Authors: Thomas von Arx, Simon S. Jensen, Michael M. Bornstein Tags: Clinical Research Source Type: research

Ridge regeneration of damaged extraction sockets using rhBMP-2: an experimental study in canine.
CONCLUSIONS: Buccal-bone-deficiency may lead to significant volume reduction after tooth extraction along the entire length of the socket, and socket grafting accompanied by rhBMP-2 or covered with a membrane can be candidate therapies for preservation of the buccolingual dimension and successful ridge regeneration. This article is protected by copyright. All rights reserved. PMID: 25946650 [PubMed - as supplied by publisher] (Source: Journal of Clinical Periodontology)
Source: Journal of Clinical Periodontology - May 6, 2015 Category: Dentistry Authors: Lee JS, Jung JS, Im GI, Kim BS, Cho KS, Kim CS Tags: J Clin Periodontol Source Type: research

Antibacterial Properties Associated with Chitosan Nanoparticle Treatment on Root Dentin and 2 Types of Endodontic Sealers
The aim of this study was to evaluate the efficacy of carboxymethyl chitosan (CMCS) and chitosan nanoparticles (CNps) to inactivate bacteria and prevent biofilm formation at sealer-dentin interfaces. (Source: Journal of Endodontics)
Source: Journal of Endodontics - May 6, 2015 Category: Dentistry Authors: Aldo del Carpio-Perochena, Anil Kishen, Annie Shrestha, Clovis Monteiro Bramante Tags: Basic Research Source Type: research

A First Step in Synthesis of a Living Pulp Tissue Replacement Using Dental Pulp MSCs and Tissue Growth Factors, Encapsulated within a Bioinspired Alginate Hydrogel
A living, self-supporting pulp tissue replacement in vitro and for transplantation is an attractive yet unmet bioengineering challenge. Our aim is to create 3-dimensional alginate-based microenvironments that replicate the shape of gutta-percha and comprise key elements for the proliferation of progenitor cells and the release of growth factors. (Source: Journal of Endodontics)
Source: Journal of Endodontics - May 6, 2015 Category: Dentistry Authors: Manasi Bhoj, Chengfei Zhang, David W. Green Tags: Basic Research Source Type: research

Salvaging an implant with damaged internal threads
Publication date: Available online 5 May 2015 Source:The Journal of Prosthetic Dentistry Author(s): Burak Yilmaz , Faye Mascarenhas (Source: The Journal of Prosthetic Dentistry)
Source: The Journal of Prosthetic Dentistry - May 6, 2015 Category: Dentistry Source Type: research

Development of oral health policy in Nigeria: an analysis of the role of context, actors and policy process
Conclusions: The OHP development succeeded through a complex inter-relationship of context, process and actors, clearly illustrating that none of these factors could have, in isolation, catalyzed the policy development. Availability of evidence is necessary but not sufficient for developing policies in this area. Wider socio-political contexts in which actors develop policy can facilitate and/or constrain actors’ roles and interests as well as policy process. These must be taken into consideration at stages of policy development in order to produce policies that will strengthen the health system, especially in low and mi...
Source: BMC Oral Health - May 6, 2015 Category: Dentistry Authors: Enyi EtiabaNkoli UguruBassey EbensoGiuliano RussoNkoli EzumahBenjamin UzochukwuObinna Onwujekwe Source Type: research

Influence of CAD/CAM tool and material on tool wear and roughness of dental prostheses after milling
Conclusion Tool lifetime calculated by volume of milled material removed should be the measure provided by CAD/CAM manufacturers instead of a number of blocks. This tool lifetime should be provided for the milling conditions associated with the material milled. Material hardness and tool grit are key factors for achieving a given roughness. (Source: The Journal of Prosthetic Dentistry)
Source: The Journal of Prosthetic Dentistry - May 6, 2015 Category: Dentistry Source Type: research

In vitro evaluation of accuracy and precision of automated robotic tooth preparation system for porcelain laminate veneers
Conclusions For the data from all sites, the experimental procedure was able to prepare the tooth model as accurately as the control, and the control procedure was able to prepare the tooth model with better precision. The experimental group showed better accuracy and precision at the finish line. (Source: The Journal of Prosthetic Dentistry)
Source: The Journal of Prosthetic Dentistry - May 6, 2015 Category: Dentistry Source Type: research

Effect of simulated mastication on the surface roughness of three ceramic systems
Conclusions The surfaces of monolithic zirconia ceramic and lithium disilicate did not become as rough as the surface of conventional feldspathic porcelain after enamel wear. (Source: The Journal of Prosthetic Dentistry)
Source: The Journal of Prosthetic Dentistry - May 6, 2015 Category: Dentistry Source Type: research

Accelerated Osteogenic OrthodonticsTM for retreatment of a patient with diminished root length and absence of the maxillary central incisor
In conclusion, surgically facilitated orthodontics (specifically, AOOTM) is an efficient and safe therapeutic tool for treating or retreating orthodontic patients with diminished root length. (Source: The Saudi Dental Journal)
Source: The Saudi Dental Journal - May 6, 2015 Category: Dentistry Source Type: research

Efficacy of mepivacaine‐tramadol combination on the success of inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis: a randomized clinical trial
ConclusionThe combination of mepivacaine‐tramadol achieved similar success rates for IANB when compared to mepivacaine 2% epinephrine 1:100000. There was no significant difference in the anaesthetic efficacy between the control and experimental solutions and none of the solutions tested were completely successful.This article is protected by copyright. All rights reserved. (Source: International Endodontic Journal)
Source: International Endodontic Journal - May 6, 2015 Category: Dentistry Authors: L. Rodríguez‐Wong, A. Pozos‐Guillen, D. Silva‐Herzog, D. Chavarría‐Bolaños Tags: Original Scientific Article Source Type: research

A 7-day recall period for a clinical application of the oral health impact profile questionnaire
Conclusion When assessed in international prosthodontic patients, OHIP scores using the new 7-day recall period were as reliable and valid as the scores using the 1-month recall period. Clinical relevance Conceptual advantages make a 7-day recall period a preferred frame of reference in clinical applications of the OHIP questionnaire. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - May 6, 2015 Category: Dentistry Source Type: research

What Hillary Clinton Could Do About the Opioid Crisis
During a recent campaign stop, presidential candidate Hillary Clinton promised to make the "quiet epidemic" involving heroin and prescription opioids an important part of her presidential campaign -- and, presumably, of her presidency, should she be elected. She mentioned the issue of substance misuse again in her highly publicized speech on criminal justice reform last week. As someone intimately familiar with the devastating impact of this public health crisis on individuals, families and communities, I was very pleased to hear this, and thought of several ways she could make good on her pledge. Here are five simple ...
Source: Science - The Huffington Post - May 5, 2015 Category: Science Source Type: news

What Hillary Clinton Could Do About the Opioid Crisis
During a recent campaign stop, presidential candidate Hillary Clinton promised to make the "quiet epidemic" involving heroin and prescription opioids an important part of her presidential campaign -- and, presumably, of her presidency, should she be elected. She mentioned the issue of substance misuse again in her highly publicized speech on criminal justice reform last week. As someone intimately familiar with the devastating impact of this public health crisis on individuals, families and communities, I was very pleased to hear this, and thought of several ways she could make good on her pledge. Here are five simple ...
Source: Healthy Living - The Huffington Post - May 5, 2015 Category: Consumer Health Advice Source Type: news

One step closer to an insulin vaccine for type 1 diabetes
An international team of researchers from Bristol, Dresden, Munich, Vienna and Denver have successfully completed the first step in the development of an insulin vaccine to prevent type 1 diabetes. (Source: University of Bristol news)
Source: University of Bristol news - May 5, 2015 Category: Universities & Medical Training Tags: Research; Faculty of Medicine and Dentistry, Faculty of Medicine and Dentistry, School of Clinical Sciences; Press Release Source Type: news

Estimating the frequency of Candida in oral squamous cell carcinoma using Calcofluor White fluorescent stain
ConclusionThe presence of Candida in OSCC solely does not justify its role in carcinogenesis. Further appraisal to evaluate a direct causal role of the micro‐organism in potentially malignant disorders and OSCC is required. (Source: Journal of Investigative and Clinical Dentistry)
Source: Journal of Investigative and Clinical Dentistry - May 5, 2015 Category: Dentistry Authors: D. S. Sanketh, Shankargouda Patil, Roopa S. Rao Tags: Original Article Source Type: research

Dimensional accuracy of different techniques used for complete‐arch multi‐implant impressions
ConclusionCasts obtained from the direct nonsplinted transfer impression technique were significantly less accurate than those obtained from the other impression techniques used in this study. (Source: Journal of Investigative and Clinical Dentistry)
Source: Journal of Investigative and Clinical Dentistry - May 5, 2015 Category: Dentistry Authors: Rabab A. Ghanem, Mohammad Z. Nassani, Kusai Baroudi, Amany Abdel Fattah Tags: Original Article Source Type: research

A comparison of the sedative effect of oral versus nasal midazolam combined with nitrous oxide in uncooperative children
Conclusion The intranasal route of midazolam administration has a quick onset of action and a quick recovery of the patient from sedation as compared to the oral route of midazolam administration. Midazolam administered through the intranasal route is as effective as the oral route at a lower dosage. Therefore, it is an effective alternative to oral route for a paediatric dental situation. (Source: European Archives of Paediatric Dentistry)
Source: European Archives of Paediatric Dentistry - May 5, 2015 Category: Dentistry Source Type: research

Impact of lateral occlusion schemes: A systematic review
Although several lateral occlusion philosophies have been proposed in the literature, there is a lack of compelling evidence supporting any scheme. (Source: Journal of Prosthetic Dentistry)
Source: Journal of Prosthetic Dentistry - May 5, 2015 Category: Dentistry Authors: Jaafar Abduo, Marc Tennant Tags: Systematic Review Source Type: research

A comparison of the sedative effect of oral versus nasal midazolam combined with nitrous oxide in uncooperative children
Conclusion The intranasal route of midazolam administration has a quick onset of action and a quick recovery of the patient from sedation as compared to the oral route of midazolam administration. Midazolam administered through the intranasal route is as effective as the oral route at a lower dosage. Therefore, it is an effective alternative to oral route for a paediatric dental situation. (Source: European Archives of Paediatric Dentistry)
Source: European Archives of Paediatric Dentistry - May 5, 2015 Category: Dentistry Source Type: research