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Psoriasis treatment guidelines proposed for patients with concomitant HCVEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Topical therapy and ultraviolet B phototherapy should be considered first-line and second-line therapies for patients with limited psoriasis and concomitant hepatitis C virus infection, suggests a consensus report from the Medical Board of the US National Psoriasis Foundation. (Source: MedWire News - Dermatology)
Source: MedWire News - Dermatology - November 21, 2009 Category: Dermatology Source Type: news

Anika Therapeutics Receives European CE Mark Approval For "ELEVESS Light"Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anika Therapeutics, Inc. (Nasdaq: ANIK), a leader in products for tissue protection, healing and repair based on hyaluronic acid ("HA") technology, announced that it has received European CE Mark approval for "ELEVESS™ Light," the Company's latest aesthetic product used for the treatment of fine lines and facial wrinkles. (Source: Dermatology News From Medical News Today)
Source: Dermatology News From Medical News Today - November 21, 2009 Category: Dermatology Tags: Dermatology Source Type: news

Incidence of Auto-Immune Pemphigus in the Midi-Pyrénées Region in 2002--2006Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dermatology (DOI:10.1159/000261503) (Source: Dermatology)
Source: Dermatology - November 20, 2009 Category: Dermatology Source Type: journals

Burns Patients Awaiting Skin Grafts: Human Embryonic Stem-Cells Could Be Used To Generate Temporary SkinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A study in this week's edition of The Lancet reports that the use of human embryonic stem-cells (hESCs) is a promising alternative for producing temporary skin substitutes for patients awaiting skin grafts after, for example, serious burn injuries. The article is the work of Dr Christine Baldeschi, INSERM and Institute for Stem Cell Therapy and Exploration of Monogenic Diseases, Evry Cedex, France, and colleagues. (Source: Dermatology News From Medical News Today)
Source: Dermatology News From Medical News Today - November 20, 2009 Category: Dermatology Tags: Stem Cell Research Source Type: news

Stem Cells May Be Used as Skin GraftsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Stem Cells May Be Used as Skin GraftsCategory: Health NewsCreated: 11/20/2009 11:01:00 AMLast Editorial Review: 11/20/2009 11:01:19 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - November 20, 2009 Category: Dermatology Source Type: consumer

Text message reminders improve sunscreen useEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Text message reminders can help increase the use of sunscreen, report US researchers. (Source: MedWire News - Dermatology)
Source: MedWire News - Dermatology - November 20, 2009 Category: Dermatology Source Type: news

Scientists reconstruct epidermis from human embryonic stem cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Scientists have succeeded in recreating a whole epidermis from human embryonic stem cells. (Source: MedWire News - Dermatology)
Source: MedWire News - Dermatology - November 20, 2009 Category: Dermatology Source Type: news

Successful use of bimatoprost in the treatment of alopecia of the eyelashesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - November 20, 2009 Category: Dermatology Authors: S. Zaheri, B. Hughes Source Type: journals

Is the Dermatology Life Quality Index really time-sensitive?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - November 20, 2009 Category: Dermatology Authors: S Esmann, GBE Jemec Source Type: journals

Birt–Hogg–Dubé syndrome: clinical and genetic studies of 10 French familiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions We report here the largest series to date of French patients with BHDS. We noted a high prevalence of thyroid nodules and renal cysts. However, the lack of a control group does not allow assessment of whether or not such association with BHDS is fortuitous. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 20, 2009 Category: Dermatology Authors: N. Kluger, S. Giraud, I. Coupier, M.-F. Avril, O. Dereure, B. Guillot, S. Richard, D. Bessis Source Type: journals

Instructions for Category 1 CME CreditEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Frontmatter Source Type: journals

Information for ReadersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Frontmatter Source Type: journals

Table of ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Frontmatter Source Type: journals

Editorial BoardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Frontmatter Source Type: journals

November iotaderma (#190)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Scott A. Norton Tags: JAAD Online Source Type: journals

Iotaderma #191Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Robert I. Rudolph Tags: JAAD Online Source Type: journals

Subject indexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Index to Volume 61 Source Type: journals

Author indexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Index to Volume 61 Source Type: journals

Cover Sheet for IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Index to Volume 61 Source Type: journals

Dermatology CalendarEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Source Type: journals

Life with epidermolysis bullosa (EB): Etiology, diagnosis, multidisciplinary care and therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This is the first new book devoted to epidermolysis bullosa (EB) to hit the shelves since Jo-David Fine's masterpiece that came out about a decade ago; the book is packed with epidemiologic data from the National EB Registry in the United States, which he founded. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Dedee F. Murrell Tags: Book Reviews Source Type: journals

Requisites in dermatology: General dermatologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
When asked to review this book, I wondered why someone would write another “general dermatology,” book and I further wondered how I could sit down and read another textbook of dermatology. Then I read the forward. The purpose of the series is to present topics—in this case, diseases—with an emphasis on the key points essential for residents and practicing clinicians. Their purpose has been fulfilled. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Erin Boh Tags: Book Reviews Source Type: journals

Circumscribed palmar hypokeratosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: Circumscribed palmar or plantar hypokeratosis (CPH) is a new entity recently described by Perez et al in 2002. To the best of our knowledge, only a few cases have been reported in the literature. It may be underdiagnosed, because most of the cases are asymptomatic, and sometimes it is misdiagnosed as palmar porokeratosis or Bowen disease. A 47-year-old woman presented to our department with an asymptomatic, solitary, circumscribed patch of depressed skin on the left thenar palm that had been present for approximately 10 years. There was no history of trauma or other notable incident. Her medications consiste...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Alejandro Fueyo-Casado, Susana Mallo-García, Convadonga Martínez-González, Jorge Santos-Juanes Tags: Case Letters Source Type: journals

Congenital dacryocystoceleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: A 5-day-old female was seen in consultation by the pediatric dermatology service for a bluish discoloration over the right medial infraorbital area. This resembled a bruise at 2 days of age. On the fifth day of life, a gradually enlarging nodule was noted in the same area that caused some distortion of her lower eyelid. On examination, there was a 9- × 7-mm, very firm blue nodule present inferior to the right medial canthus (). There was no purulent drainage. The differential diagnosis included a deep infantile hemangioma or a midline developmental defect; however, a diagnosis of dacryocystocele was favored...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Sheila M. Greenlaw, Keri S. Chaney, Leah Belazarian, Karen Wiss Tags: Case Letters Source Type: journals

Persistent agmination of lymphomatoid papulosis evolving to classical lesions of lymphomatoid papulosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: Heald et al described seven patients with what they called persistent agmination of lymphomatoid papulosis (LyP) and classified them as a distinct clinical subset within CD30+ lymphoproliferative disorders. Patients had waxing and waning papules and nodules within a persistent erythematous and scaly plaque, histopathologically compatible with a LyP, but with a different clinical behavior. We observed a similar case with the same clinical presentation but a distinct clinical evolution. A 27-year-old male without medical history had a 4-month history of several asymptomatic, stable nodules between 10 and 20 mm...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Alberto Romero-Maté, Luz Martín-Fragueiro, Román Miñano-Medrano, Cristina Martinez-Morán, Dolores Arias-Palomo, Jesús Borbujo Tags: Case Letters Source Type: journals

Radiation recall dermatitis induced by erlotinibEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of radiation recall dermatitis induced by erlotinib, a selective epidermal growth factor receptor (EGFR) inhibitor. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Jean-Noël Dauendorffer, Alain Dupuy Tags: Research Letters Source Type: journals

Videodermatoscopy enhances diagnostic capability in psoriatic balanitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: Balanitis is an inflammatory condition of the glans penis that may be caused by a wide range of dermatologic conditions, including psoriasis. Psoriatic balanitis is clinically characterized by erythematous, nonscaling plaques most commonly located proximally on the glans and under the prepuce. Most often, genital psoriasis is part of a more generalized disease process, but in the case of exclusively penile involvement, the correct diagnosis may be difficult to make, and several investigations, including a skin biopsy, are often necessary. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Francesco Lacarrubba, Maria Rita Nasca, Giuseppe Micali Tags: Research Letters Source Type: journals

Patient preferences for dermatology visitsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: In recent years, multiple sources have reported long wait times for new patient appointments in some major metropolitan cities across the United States. However, little information has been collected pertaining to patient perceptions of these wait times and consumer preferences for dermatology visits compared to other providers in terms of access. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Jane Y. Yoo, Darcy L. Pancir, Alexa B. Kimball Tags: Research Letters Source Type: journals

Reporting clinical trials: Why one plus one does not equal twoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: We read with interest Thiboutot et al's November 2008 report of safety and efficacy of a product containing clindamycin phosphate 1.2% and benzoyl peroxide 2.5% for treatment of acne. In the report, Thiboutot et al present combined data from two randomized controlled trials (RCTs) as if the two RCTs were in fact one large RCT. Unfortunately, such an approach is invalid. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Kenneth A. Katz, Clara Y. Kim, Hywel C. Williams Tags: Notes & Comments Source Type: journals

Physiologic changes in vascular birthmarks during early infancy: Mechanisms and clinical implicationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: In the April 2009 issue of the Journal, Cordoro et al stated that physiologic vascular changes in infants may alter the appearance of some vascular birthmarks; they incorrectly suggested that these changes contribute to the efficacy of pulsed dye laser (PDL) treatment of port wine stains (PWS) in infancy. We have recently shown that high energy PDL of PWS before 6 months of age offers the best chance of eradication of these lesions. Factors related to laser–tissue interactions are far more responsible for this high cure rate than are physiologic changes in the vasculature. (Source: Journal of the American ...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Anne M. Chapas, Roy G. Geronemus Tags: Notes & Comments Source Type: journals

Nonmelanoma skin cancer in vitiligo patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: In the June 2009 issue of the Journal, Hexsel et al reported the incidence of nonmelanoma skin cancer (NMSC) in a cohort of patients with vitiligo. In the “Introduction” section, they noted that the frequency of skin cancer in patients with vitiligo seems to be uncommon, with only a few reports in the literature. They identified 477 patients at their hospital with vitiligo, six of whom (42% of the study group) had a NMSC. Four were basal cell carcinomas, and two were squamous cell carcinomas (SCCs). The pathology specimens were stained for the presence of melanocytes. Two of the six cancers arose in viti...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: James J. Nordlund Tags: Notes & Comments Source Type: journals

Tinea capitis treatment in SpainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report the authors compared the efficacy and safety of terbinafine hydrochloride oral granules with that of oral griseofulvin suspension in children with tinea capitis. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Anouk Jaén-Larrieu, Asunción Vicente-Villa, Paula Aguilera-Pérez, María Antonia González-Enseñat, Teresa Juncosa-Morros, Victoria Fumadó-Pérez Tags: Notes & Comments Source Type: journals

Freedom of expression or protectionism in the debate on sentinel node biopsy in melanomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: The Organizing Committee of the 6th Biennial International Sentinel Node Society (ISNS) Meeting in Sydney, Australia, held from February 18-20, 2008, refused to allow any presentations from the podium that did not support sentinel node biopsy (SNB) in melanoma. The members of the international panel who prepared the subsequent “consensus statement” all represented the same opinion. All but one of the references cited in the May 2009 commentary by Balch et al in the Journal were written by the authors themselves. As a result, it is my opinion that both the commentary and the consensus statement are biased...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: J. Meirion Thomas Tags: Notes & Comments Source Type: journals

Volunteers NeededEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Source Type: journals

CorrectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patel RV, Clark LN, Lebwohl M, Weinberg JM. Treatments for psoriasis and the risk of malignancy. J Am Acad Dermatol 2009;60:1001-17. On page 1002 of the article above, the following statement was incorrect: Patients with mild psoriasis have a relative risk of 1.42 and 3.18 of developing Hodgkin's lymphoma and CTCL, respectively. Patients with severe psoriasis have a relative risk of 4.10 and 10.75 of developing Hodgkin's lymphoma and CTCL, respectively. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Corrections Source Type: journals

CorrectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Lupi O, Bartlett BL, Haugen RN, Dy LC, Sethi A, Klaus SN, Machado Pinto J, Bravo F, Tyring SK. Tropical dermatology: Tropical diseases caused by protozoa. J Am Acad Dermatol 2009;60:897-925. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Tags: Corrections Source Type: journals

Immunomodulatory therapy of cutaneous T-cell lymphoma: A multimodality approach in advanced diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Jacqueline M. Junkins-Hopkins, MD, are provided after each discussion as a topic summary and are provided here as a special service to readers of the Journal of the American Academy of Dermatology. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Jacqueline M. Junkins-Hopkins Tags: Dialogues in Dermatology Source Type: journals

Pain associated with aminolevulinic acid-photodynamic therapy of skin diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Gamma-aminobutyric acid receptors, cold/menthol receptors (transient receptor potential cation channel, subfamily M, member 8), and vanilloid/capsaicin receptors (transient receptor potential cation channel, subfamily V, member 1) may be involved in pain perception during ALA-PDT and are therefore worthy of further investigation. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Christine B. Warren, Laszlo J. Karai, Allison Vidimos, Edward V. Maytin Tags: Reviews Source Type: journals

Initial presentation of stasis dermatitis mimicking solitary lesions: A previously unrecognized clinical scenarioEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Stasis dermatitis may present as a solitary lesion mimicking a neoplasm. Early recognition of stasis dermatitis can lead to appropriate treatment and possibly prevent further morbidity. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Joshua Weaver, Steven D. Billings Tags: Dermatopathology Source Type: journals

Microscopically differentiating dermatophytes from sock fibersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: While textile fibers may be present in KOH preparations, their general appearance typically differs from that of dermatophytes; an observer who is familiar with these distinctions will be able to differentiate between the two. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Abraar Karan, Ali Alikhan, Steven R. Feldman Tags: Dermatopathology Source Type: journals

Surgical management of congenital dermatofibrosarcoma protuberansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Congenital dermatofibrosarcoma protuberans (DFSP) is a rare tumor with varying clinical presentations that is commonly misdiagnosed. Treatment of congenital DFSP is complicated by delays in diagnosis and its propensity for subclinical spread. Of 61 reported cases, 11 (18%) were treated with Mohs micrographic surgery (MMS) and 46 (75%) were treated with wide local excision (WLE). One case was treated with imatinib, and the remaining 3 did not differentiate between receiving MMS or WLE. In the cases of congenital DFSP treated with MMS the clearance rate was 100% with an average follow-up of 4.3 years. The clearance rate seen...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: W. Elliot Love, Susan A. Keiler, Joan E. Tamburro, Kord Honda, Arun K. Gosain, Jeremy S. Bordeaux Tags: Dermatologic Surgery Source Type: journals

Change of AddressEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Source Type: journals

Answers to CME examinationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Source Type: journals

CME examinationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Source Type: journals

Earn CME and MOC Credits Through a New Online e-Blue FeatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Source Type: journals

Angiogenesis in cutaneous disease: Part IIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This review will discuss the role of angiogenesis in specific cutaneous diseases. Scientific evidence now points to the role of angiogenesis in tumor development and many other cutaneous disorders. Angiogenesis is a complex process that involves angiogenic growth factors and inhibitors, many of which could be a potential target for pharmacologic intervention. Antiangiogenic agents have recently been applied to dermatologic diseases with promising efficacy.Learning objectives: After completing this learning activity, participants should be able to recognize cutaneous diseases where angiogenesis is likely to be an important ...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Vivian Laquer, Van Hoang, Amy Nguyen, Kristen M. Kelly Source Type: journals

American Board of Dermatology Examination DatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Source Type: journals

Angiogenesis in cutaneous disease: Part IEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Angiogenesis is an important process in normal physiology and disease pathogenesis. Angiogenesis is controlled in a healthy body by a system of angiogenic growth factors and angiogenesis inhibitors. When angiogenic growth factors are predominantly expressed, blood vessel growth occurs and disease may result. Successful therapies have been developed that target growth factors, their receptors, or the cascade pathways that are activated by growth factor/receptor interactions. There is good evidence that angiogenesis plays an important role in a wide range of cutaneous maladies, and angiogenesis-targeting therapies are playin...
Source: Journal of the American Academy of Dermatology - November 19, 2009 Category: Dermatology Authors: Amy Nguyen, Van Hoang, Vivian Laquer, Kristen M. Kelly Tags: Continuing Medical Education Source Type: journals