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Basic measures and systemic medical treatment of patients with toxic epidermal necrolysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Immediate beginning of therapy is essential for a successful treatment of toxic epidermal necrolysis. Besides systemic therapy with corticosteroids, certain basic measures such as isolation of patients at adequate room temperature to prevent hypothermia, strict control of circulation, temperature and laboratory parameters, daily smears of skin and mucous membranes and a diet rich in calories due to the catabolic metabolic status are very important for successful outcome.
Source: JDDG - October 22, 2009 Authors: Imke Hanken, Melanie Schimmer, Christian A. Sander

Acceleration of permeability barrier recovery by exposure of skin to 10–30 kHz soundemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions These results suggest that epidermal keratinocytes might be influenced by ultrasound in a manner that results in modulation of epidermal permeability barrier homeostasis.
Source: British Journal of Dermatology - October 22, 2009 Authors: M. Denda, M. Nakatani

Upregulation of cathepsin S in psoriatic keratinocytesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Upregulation of cathepsin S in psoriatic keratinocytes. Experimental Dermatology 2009.Abstract: Cathepsin S (CATS) is a cysteine protease, well known for its role in MHC class II-mediated antigen presentation and extracellular matrix degradation. Disturbance of the expression or metabolism of this protease is a concomitant feature of several diseases. Given this importance we studied the localization and regulation of CATS expression in normal and pathological human/mouse skin. In normal human skin CATS-immunostaining is mainly present in the dermis and is localized in macrophages, Langerhans, T-...
Source: Experimental Dermatology - October 22, 2009 Authors: Alexander Schönefuß, Wiebke Wendt, Benjamin Schattling, Roxane Schulten, Klaus Hoffmann, Markus Stuecker, Christian Tigges, Hermann Lübbert, Christine Stichel

Dysregulation of CD36 upon TLR-2 stimulation in monocytes from patients with atopic dermatitis and the TLR2 R753Q polymorphismemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The differences in CD36 expression in TLR-2 polymorph AD patients compared to wild type AD patients and healthy controls may be associated with an enhanced susceptibility to skin infections with S. aureus.
Source: Experimental Dermatology - October 22, 2009 Authors: Margarete Niebuhr, Jens Langnickel, Stefanie Sigel, Thomas Werfel

Influence of narrowband UVB phototherapy on vitamin D and folate statusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Low-dose nUVB treatment gives a significant increase (P < 0.001) of the vitamin D status in persons with low initial levels of 25(OH)D, but no effect on the folate level.
Source: Experimental Dermatology - October 22, 2009 Authors: Emanuela Cicarma, Cato Mørk, Alina Carmen Porojnicu, Asta Juzeniene, Tran Thi Thu Tam, Arne Dahlback, Johan Moan

Mouse models for melanoma: a personal perspectiveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Mouse models for melanoma: a personal perspective. Experimental Dermatology 2009.Abstract: Complex biological processes often require in vivo analysis, and many important research advances have been made using mice as a model for the study of various biological systems. Cutaneous melanomas are tumors originating from skin melanocytes, which are present in hair follicles, and interfollicular epidermal and dermal layers. Until recently, mouse melanoma models were largely based on transplantation models, i.e. transplantation of either syngeneic or xenogeneic melanoma cells into wild type or genetica...
Source: Experimental Dermatology - October 22, 2009 Authors: Jürgen C. Becker, Roland Houben, David Schrama, Heike Voigt, Selma Ugurel, Ralph A. Reisfeld

Effect of topical application and intraperitoneal injection of oregonin on atopic dermatitis in NC/Nga miceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Effect of topical application and intraperitoneal injection of oregonin on atopic dermatitis in NC/Nga mice. Experimental Dermatology 2009.Abstract: The diarylheptanoid, oregonin (ORE), which was isolated from the bark of Alnus japonica Steudel that grows natively in Korea, has been known to exert antioxidative, anti-inflammatory, anti-cancer and immune response inhibitory effects. The antioxidative effect of ORE was observed on the superoxide and 1,1-diphenyl-2-picrylhydrazyl radical, as well as on the expression of inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide-treat...
Source: Experimental Dermatology - October 22, 2009 Authors: Sun Eun Choi, Mi Sook Jeong, Myung Joo Kang, Do Ik Lee, Seong Soo Joo, Chung Soo Lee, Hyoweon Bang, Mi-Kyung Lee, Soon-Chul Myung, Young Wook Choi, Kap-sok Lee, Seong Jun Seo, Min Won Lee

Successful treatment of cheilitis granulomatosa with intralesional injection of triamcinoloneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Journal of the European Academy of Dermatology and Venereology - October 22, 2009 Authors: C Bacci, ML Valente

Topical Antibiotic Treatment for Uncomplicated Skin and Skin Structure Infections: Review of the Literatureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Are topical antibiotic treatment options for uncomplicated skin infections effective? Expert Review of Anti-Infective Therapy
Source: Medscape Dermatology Headlines - October 21, 2009 Tags: Infectious Diseases

With Microdermabrasion, Rough Seems to Work Betteremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: With Microdermabrasion, Rough Seems to Work BetterCategory: Health NewsCreated: 10/21/2009 8:10:00 AMLast Editorial Review: 10/21/2009
Source: MedicineNet Skin General - October 21, 2009

About the cutaneous targets of bexarotene in CTCL patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: About the cutaneous targets of bexarotene in CTCL patients. Experimental Dermatology 2009.Abstract: There are several approved therapies for cutaneous T-cell lymphoma (CTCL). The retinoids are one of the major biologic response modifiers used in CTCL, producing good response rates but few complete responses. Bexarotene has been demonstrated to act on malignant T-cells by inducing their apoptosis, but nothing is known about its role on keratinocytes and Langerhans cells. Immunohistochemical analysis using CD1a, HLA-DR, ICAM-1 (activation markers), CD95 and CD40 (apoptosis markers) was conducted on...
Source: Experimental Dermatology - October 21, 2009 Authors: Anne Chantal Knol, Gaëlle Quéreux, Anabelle Brocard, Fabienne Ballanger, Amir Khammari, Jean-Michel Nguyen, Brigitte Dréno

Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes. Experimental Dermatology 2009: 00: 000[ndash]000.Abstract: Honey has been used since ancient times as a remedy in wound healing. However, even though the results from randomized clinical trials document that honey accelerates wound healing, no study dealing with its influence on human skin cells (epidermal keratinocytes and dermal fibroblast) has been performed. We demonstrate that keratinocytes, which are known to be involved in wound healing, are responsible for elevated production...
Source: Experimental Dermatology - October 21, 2009 Authors: Juraj Majtan, Pawan Kumar, Tomas Majtan, Andrew F. Walls, Jaroslav Klaudiny

Absence of modulation of CD4+CD25high regulatory T cells in CTCL patients treated with bexaroteneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Absence of modulation of CD4+CD25high regulatory T cells in CTCL patients treated with bexarotene. Experimental Dermatology 2009.Abstract: Cutaneous T-cell lymphoma (CTCL) are a heterogeneous group of lymphoproliferative disorders, characterized by the infiltration of the epidermis by mature and activated malignant CD4+ T-lymphocytes. Retinoids such as retinoic acid and synthetic analogues have long been used alone or in combination with other therapies for CTCL. Bexarotene, the first synthetic highly selective RXR retinoid, was approved for the treatment of all stages of CTCL in patients refract...
Source: Experimental Dermatology - October 21, 2009 Authors: Anne Chantal Knol, Gaëlle Quéreux, Anabelle Brocard, Fabienne Ballanger, Amir Khammari, Jean-Michel Nguyen, Brigitte Dréno

Probing tumor and peritumoral tissues in superficial and nodular basal cell carcinoma using polarized Raman microspectroscopyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study reports the use of polarized Raman microspectroscopy on the nodular and superficial types to discriminate between healthy epidermis and tumor, and between normal and peritumoral stroma. This technique probes additional information than conventional Raman spectroscopy because it is sensitive to the molecular ordering of tissue components. Depolarization ratios and hierarchical cluster analysis demonstrate that polarized Raman microspectroscopy can better identify the tumor and the peritumoral dermis than conventional Raman microspectroscopy, and hence gives potential complementary data about their molecular chara...
Source: Experimental Dermatology - October 21, 2009 Authors: Elodie Ly, Anne Durlach, Frank Antonicelli, Philippe Bernard, Michel Manfait, Olivier Piot

Nestin and SOX9 and SOX10 transcription factors are coexpressed in melanomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, the expression levels of nestin, BRN2, SOX9 and SOX10 were analysed in tissues of melanoma (n = 78) and melanocytic nevi (n = 26) by immunohistochemistry. All proteins were highly expressed in primary and metastatic melanomas and, apart from BRN2, showed much lower levels in melanocytic nevi. Significant coexpression of nestin with SOX9 and SOX10 was found in primary melanoma confirming our in vitro data. Correlation analysis with clinicopathological data revealed that nestin was significantly associated with presence of ulceration in primary tumors and SOX9 with more advanced stage of disease. Our data reve...
Source: Experimental Dermatology - October 21, 2009 Authors: Renato M. Bakos, Tanja Maier, Robert Besch, Dominik S. Mestel, Thomas Ruzicka, Richard A. Sturm, Carola Berking

The NF-κB signalling pathway is involved in the LPS/IL-2-induced upregulation of FoxP3 expression in human CD4+CD25high regulatory T cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: The NF-[kappa]B signalling pathway is involved in the LPS/IL-2-induced upregulation of FoxP3 expression in human CD4+CD25high regulatory T cells. Experimental Dermatology 2009.Abstract: Regulatory T cells (Treg) have been found to be central for host defense regulation against microbial antigens, the prevention of allergic and autoimmune diseases and the suppression of effective tumor immune responses. However, the influence of the microenvironment and the mechanisms leading to their activation in the periphery still remain unclear. In vitro infection models revealed that survival and suppressive...
Source: Experimental Dermatology - October 21, 2009 Authors: Linda Milkova, Verena Voelcker, Inka Forstreuter, Ulrich Sack, Ulf Anderegg, Jan-C. Simon, Corinna Maier-Simon

Corrigendumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Experimental Dermatology - October 21, 2009

Fluorescence induction of protoporphyrin IX by a new 5-aminolevulinic acid nanoemulsion used for photodynamic therapy in a full-thickness ex vivo skin modelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Fluorescence induction of protoporphyrin IX by a new 5-aminolevulinic acid nanoemulsion used for photodynamic therapy in a full-thickness ex vivo skin model. Experimental Dermatology 2009.Abstract: An ex vivo porcine skin model was utilized to analyse the penetration of 5-aminolevulinic acid (5-ALA) contained in a nanoemulsion-based formulation BF-200 ALA (10% 5-ALA-hydrochloride) versus 16% aminolevulinate methyl ester-hydrochloride in a commercially cream (MAL cream) by fluorescence microscopy of their common metabolite protoporphyrin IX (PpIX) after 3, 5, 8 and 12 h. Fluorescence signals of Pp...
Source: Experimental Dermatology - October 21, 2009 Authors: Tim Maisch, Francesco Santarelli, Stephan Schreml, Philipp Babilas, Rolf-Markus Szeimies

Lipidome of narrow-band ultraviolet B irradiated keratinocytes shows apoptotic hallmarksemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: NB-UVB affected the cellular lipidome of keratinocytes in strictly apoptosis-specific manner.
Source: Experimental Dermatology - October 21, 2009 Authors: Adam Reich, Dominik Schwudke, Michael Meurer, Bodo Lehmann, Andrej Shevchenko

Personalien und Tagesnachrichtenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:104 (DOI:10.1159/000252967)
Source: Dermatology - October 21, 2009

Buchbesprechungenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:103-104 (DOI:10.1159/000252966)
Source: Dermatology - October 21, 2009

Société Française de Dermatologie et de Syphiligraphieemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:97-103 (DOI:10.1159/000252965)
Source: Dermatology - October 21, 2009

Zur Therapie der Hauttuberkulose unter besonderer Berücksichtigung des Lupus vulgarisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:87-96 (DOI:10.1159/000252964)
Source: Dermatology - October 21, 2009

Der Tripperemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:46-86 (DOI:10.1159/000252963)
Source: Dermatology - October 21, 2009

Die chemotherapeutische Wirksamkeit der Goldverbindung des Derivates eines natürlichen Schwefeleiweißesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:39-45 (DOI:10.1159/000252962)
Source: Dermatology - October 21, 2009

Über Hauterscheinungen bei Trichinoseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:34-39 (DOI:10.1159/000252961)
Source: Dermatology - October 21, 2009

Zur Behandlung des rezidivierenden Herpesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:27-33 (DOI:10.1159/000252960)
Source: Dermatology - October 21, 2009

Klinische und kulturelle Beobachtungen bei Achorion Quinckeanumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:21-27 (DOI:10.1159/000252959)
Source: Dermatology - October 21, 2009

Zur Frage der Ätiologie, Therapie und Prophylaxe der Hautschädigungen durch Salvarsanemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1934;68:1-20 (DOI:10.1159/000252958)
Source: Dermatology - October 21, 2009

Personalien und Tagesnachrichtenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:394 (DOI:10.1159/000252956)
Source: Dermatology - October 21, 2009

Buchbesprechungenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:391-394 (DOI:10.1159/000252955)
Source: Dermatology - October 21, 2009

Société Française de Dermatologie et de Syphiligraphieemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:382-390 (DOI:10.1159/000252954)
Source: Dermatology - October 21, 2009

Royal Society of Medicine. Section of Dermatologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:380-382 (DOI:10.1159/000252953)
Source: Dermatology - October 21, 2009

Die Bedeutung des elektrischen Schneidens mit der Drahtschlinge für die Behandlung der Hautkrankheitenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:370-380 (DOI:10.1159/000252952)
Source: Dermatology - October 21, 2009

Syphilis und andere Spirochätosenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:340-370 (DOI:10.1159/000252951)
Source: Dermatology - October 21, 2009

Schlußwort zu vorstehenden Bemerkungen / Bemerkungen zur Arbeit von v.Vonno und J. Struycken (Bäckerekzem)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:338-339 (DOI:10.1159/000252950)
Source: Dermatology - October 21, 2009

Weitere klinische und tierexperimentelle Untersuchungsergebnisse über die Ursache der Berufsekzeme bei Bäckernemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:337 (DOI:10.1159/000252949)
Source: Dermatology - October 21, 2009

Erfahrungen mit der Flavadinbehandlung der weiblichen Gonorrhoeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:331-336 (DOI:10.1159/000252948)
Source: Dermatology - October 21, 2009

Phytogene Hauterkrankungen, mit besonderer Rücksicht auf die Wiesendermatitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologische Zeitschrift 1933;67:324-331 (DOI:10.1159/000252947)
Source: Dermatology - October 21, 2009

Internet-supported gathering of treatment data and patient benefits in psoriasisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion The findings suggest that patients in the online sample are less satisfied with their health care, which also could have been their motive for participating online. It is important to gather data online because it increases the data pool and permits inclusion of people who are not incorporated in clinical settings. However, online data cannot directly replace data collected in clinics because they are also subject to selections.
Source: Journal of the European Academy of Dermatology and Venereology - October 21, 2009 Authors: AK Langenbruch, I Schäfer, N Franzke, M Augustin

Treatment of scalp psoriasis with clobetasol-17 propionate 0.05% shampoo: a study on daily clinical practiceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Short-contact treatment with clobetasol-17 propionate 0.05% shampoo has high user convenience and patient satisfaction rates. Moreover, the treatment is well-tolerated and efficacious from patients' perspective. Subgroup analyses did not reveal factors predicting treatment outcome, although treatment success tended to be more evident in patients who had received fewer treatments previously.
Source: Journal of the European Academy of Dermatology and Venereology - October 21, 2009 Authors: HJ Bovenschen, PCM Van de Kerkhof

Residents Lack Skill in Skin Cancer Exams (CME/CE)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Opportunities to learn how to perform skin cancer examinations during medical training are inadequate, with three-quarters of residents reporting never having been taught this skill, a survey found.
Source: MedPage Today Dermatology - October 20, 2009

Medications for RA Linked to Skin Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Medications for RA Linked to Skin CancerCategory: Health NewsCreated: 10/20/2009 11:18:00 AMLast Editorial Review: 10/20/2009 11:18:19 AM
Source: MedicineNet Skin General - October 20, 2009

More Doctors Need to Learn to Spot Skin Cancersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: More Doctors Need to Learn to Spot Skin CancersCategory: Health NewsCreated: 10/19/2009 4:10:00 PMLast Editorial Review: 10/20/2009
Source: MedicineNet Skin General - October 20, 2009

Angiokeratoma: a cutaneous marker of Fabry's diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The initial symptoms of Fabry's disease (FD) may seem harmless and may delay its diagnosis. A survey and screening for FD were performed on men with biopsy-proven angiokeratoma and some of their relatives (n = 29). Three patients were identified. Dermatologists should be aware of this prominent early feature and investigate unexplained cutaneous vascular lesions to detect FD.
Source: Clinical And Experimental Dermatology - October 20, 2009 Authors: L. M. J. Albano, C. Rivitti, D. R. Bertola, R. S. Honjo, S. V. Kelmann, R. Giugliani, C. A. Kim

THE CUTTING EDGE: Fractional Photothermolysis: A New Therapeutic Modality for Xanthelasmaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Archives of Dermatology - October 19, 2009 Authors: Katz, T. M., Goldberg, L. H., Friedman, P. M. Tags: Ophthalmology, Ophthalmological Disorders, External Eye Disease, Dermatology, Dermatologic Disorders, Dermatologic Disorders, Other, Dermatologic Procedures, Dermatologic Procedures, Other The Cutting Edge

STUDY: Large Sample of Nephrogenic Systemic Fibrosis Cases From a Single Institutionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  Despite the limitations, this study, which reviewed a large number of patients who underwent intravascular GBCA injections, demonstrates a 77-fold higher risk of NSF among patients who undergo hemodialysis and a 69-fold higher risk in patients with renal transplantation. This increased risk is thought to be associated with poor clearance of most GBCAs.
Source: Archives of Dermatology - October 19, 2009 Authors: Lee, C. U., Wood, C. M., Hesley, G. K., Leung, N., Bridges, M. D., Lund, J. T., Lee, P. U., Pittelkow, M. R. Tags: Dermatology, Dermatologic Disorders, Renal Diseases, Dialysis, Renal Diseases, Other, Transplantation, Kidney Transplantation, Dermatologic Disorders, Other Study

STUDY: Highly Sensitive Multivariable Assay Detection of Melanocytic Differentiation Antigens and Angiogenesis Biomarkers in Sentinel Lymph Nodes With Melanoma Micrometastasesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  Quantitative assessment of melanocytic differentiation antigens in SLNs, which has prognostic value, is more specific than qualitative assessment. Prognosis may be more effectively predicted by the combination of quantitative assessment of melanocytic differentiation antigens in SLNs with histologic assessment. A significant association was found between the presence of micrometastases and the expression of angiogenesis biomarkers.
Source: Archives of Dermatology - October 19, 2009 Authors: Vitoux, D., Mourah, S., Kerob, D., Verola, O., Basset-Seguin, N., Baccard, M., Schartz, N., Ollivaud, L., Archimbaud, A., Servant, J.-M., Revol, M., Toubert, M.-E., Podgorniak, M.-P., Plassa, F., Porcher, R., Lebbe, C. Tags: Oncology, Skin Cancer, Oncology, Other, Dermatology, Dermatologic Disorders, Neoplasms, Diagnosis, Prognosis/ Outcomes Study

NOTABLE NOTES: The Incredible Being of Lightnessemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Archives of Dermatology - October 19, 2009 Authors: Bernhardt, M. Tags: Humanities Notable Notes

STUDY: Molecular Analysis of Aggressive Microdermabrasion in Photoaged Skinemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  Microdermabrasion using a coarse diamond-studded handpiece induces a dermal remodeling cascade similar to that seen in incisional wound healing. Optimization of these molecular effects is likely the result of more aggressive treatment with a more abrasive handpiece. Trial Registration  clinicaltrials.gov Identifier: NCT00111254
Source: Archives of Dermatology - October 19, 2009 Authors: Karimipour, D. J., Rittie, L., Hammerberg, C., Min, V. K., Voorhees, J. J., Orringer, J. S., Sachs, D. L., Hamilton, T., Fisher, G. J. Tags: Aging/ Geriatrics, Dermatology, Dermatologic Disorders, Wound Healing, Dermatologic Procedures, Dermatologic Procedures, Other, Dermatology, Other, Facial Plastic Surgery, Cosmetic Surgery/ Procedures, Dermabrasion/ Chemical Peels, Facial Plastic Surgery,