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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 20.
Combined ivermectin and topical therapy significantly reduces treatment time in aged scabietic patients
Source: The Journal of Dermatology - January 5, 2013 Category: Dermatology Authors: Miki Ichikawa, Maya Tanaka, Yuji Naritomi, Masutaka Furue Tags: Letter to the Editor Source Type: research
Consensus guidelines for the management of atopic dermatitis: An Asia–Pacific perspective
Abstract Atopic dermatitis (AD) is a relatively common disease in patients in the Asia–Pacific region. It presents a particular clinical challenge and requires careful clinical management. The chronic nature of AD characterized by flares, exacerbations and periods of quiescence requires a multipronged approach aimed at reducing itch, inflammation and the appearance of secondary lesions. In addition, varying levels of maintenance therapy may be required to avoid exacerbations. Survey data from the region indicate that there is significant variation across the Asia–Pacific with regard to current treatment practices. The ...
Source: The Journal of Dermatology - January 5, 2013 Category: Dermatology Authors: Diana Rubel, Thiru Thirumoorthy, Retno W. Soebaryo, Steven C. K. Weng, Teresita M. Gabriel, Lillian L. Villafuerte, Chia‐Yu Chu, Sandipan Dhar, Deepak Parikh, Li‐Chuen Wong, Kuen‐Kong Lo, Tags: Original Article Source Type: research
RNAi functionalized collagen-chitosan/silicone membrane bilayer dermal equivalent for full-thickness skin regeneration with inhibited scarring.
Abstract Scar inhibition of dermal equivalent is one of the key issues for treatment of full thickness skin defects. To yield a bioactive RNAi functionalized matrix for skin regeneration with inhibited scarring, collagen-chitosan/silicone membrane bilayer dermal equivalent (BDE) was combined with trimetylchitosan (TMC)/siRNA complexes which could induce suppression of transforming growth factor-β1 (TGF-β1) pathway. The RNAi-BDE functioned as a reservoir for the incorporated TMC/siRNA complexes, enabling a prolonged siRNA release. The seeded fibroblasts in the RNAi-BDE showed good viability, internalized the TMC/s...
Source: Biomaterials - January 4, 2013 Category: Materials Science Authors: Liu X, Ma L, Liang J, Zhang B, Teng J, Gao C Tags: Biomaterials Source Type: research
Porocarcinoma: an exceedingly rare tumor or a tumor eclipse phenomenon?—Reply
At the outset, we thank the author for the in-depth study of our article and apologize for any entirely unintentional discrepancies. We would, however, like to emphasize that the premise of the study was in differentiating porocarcinoma from squamous cell carcinoma and the utility of immunohistochemical stains as a histopathologic adjunct in the differentiation of these 2 entities—it was never meant to be an epidemiological study. Having said that, the authors (M. M. and M. H.) stand by their original contention that the frequency of porocarcinoma is not as high as that encountered by Dr Urso based on their more than 20 ...
Source: Human Pathology - January 4, 2013 Category: Pathology Authors: Meera Mahalingam, Mai P. Hoang Tags: Correspondence Source Type: research
Occupational airborne contact dermatitis caused by usnic acid in a domestic worker.
PMID: 23295019 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - January 4, 2013 Category: Allergy & Immunology Authors: Pacheco D, Travassos AR, Antunes J, Soares de Almeida L, Filipe P, Correia T Tags: Allergol Immunopathol (Madr) Source Type: research
Nephrogenic Systemic Fibrosis-Like Effects of Magnetic Resonance Imaging Contrast Agents in Rats with Adenine-Induced Renal Failure
Nephrogenic systemic fibrosis (NSF) is a scleroderma-like disease associated with prior administration of certain gadolinium chelates (GCs). NSF occurs in patients with severe renal failure. The purpose of this study was to set up a rat model of GC-associated NSF to elucidate the mechanism of this devastating disease. Firstly, after characterization of the model, male Wistar rats received a 0.75% adenine-enriched diet for 8, 14, or 16 days to obtain various degrees of renal failure. Rats received five consecutive daily iv injections of saline or gadodiamide (2.5 mmol/kg/day). Secondly, the safety profile and in vivo propen...
Source: Toxicological Sciences - January 4, 2013 Category: Toxicology Authors: Fretellier, N., Bouzian, N., Parmentier, N., Bruneval, P., Jestin, G., Factor, C., Mandet, C., Daubine, F., Massicot, F., Laprevote, O., Hollenbeck, C., Port, M., Idee, J.-M., Corot, C. Tags: Research Article Source Type: research
Effects of Parabens on Adipocyte Differentiation
Parabens are a group of alkyl esters of p-hydroxybenzoic acid that include methylparaben, ethylparaben, propylparaben, butylparaben, and benzylparaben. Paraben esters and their salts are widely used as preservatives in cosmetics, toiletries, food, and pharmaceuticals. Humans are exposed to parabens through the use of such products from dermal contact, ingestion, and inhalation. However, research on the effects of parabens on health is limited, and the effects of parabens on adipogenesis have not been systematically studied. Here, we report that (1) parabens promote adipogenesis (or adipocyte differentiation) in murine 3T3-...
Source: Toxicological Sciences - January 4, 2013 Category: Toxicology Authors: Hu, P., Chen, X., Whitener, R. J., Boder, E. T., Jones, J. O., Porollo, A., Chen, J., Zhao, L. Tags: Research Article Source Type: research
Activated LTB4 pathway in muscle tissue of patients with polymyositis or dermatomyositis
Conclusion The LTB4 pathway is upregulated in muscle tissue from patients with PM/DM and this upregulation correlated negatively to muscle performance, suggesting a role for LTB4 in myositis muscle weakness. The immunosuppressive treatment was insufficient on the LTB4 pathway and, for patients with high expression of FLAP, FLAP inhibitors may be considered as possible therapy.
Source: Annals of the Rheumatic Diseases - January 4, 2013 Category: Rheumatology Authors: Loell, I., Alemo Munters, L., Pandya, J., Zong, M., Alexanderson, H., Fasth, A. E., Stahl Hallengren, C., Radmark, O., Lundberg, I. E., Jakobsson, P.-J., Korotkova, M. Tags: Immunology (including allergy), Muscle disease, Connective tissue disease, Musculoskeletal syndromes Basic and translational research Source Type: research
Allergic Contact Dermatitis to Fragrances: Part 2.
Abstract Allergic contact dermatitis due to fragrances usually manifests as subacute or chronic dermatitis because fragrances are found in a wide range of products to which patients are repeatedly exposed. The typical patient is a middle-aged woman with dermatitis on her hands and face, although other sites may be affected depending on the allergen and the product in which it is found. The standard patch test series of the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) contains 4 fragrance markers: balsam of Peru, fragrance mix i, fragrance mix ii, and lyral. Testing with a specific fragrance s...
Source: Actas Dermo-Sifiliograficas - January 3, 2013 Category: Dermatology Authors: Arribas MP, Soro P, Silvestre JF Tags: Actas Dermosifiliogr Source Type: research
Claudin-5 Controls Intercellular Barriers of Human Dermal Microvascular but not Human Umbilical Vein Endothelial Cells.
CONCLUSIONS: Claudin-5 expression and junctional organization control HDMEC and arteriolar-capillary paracellular barriers, whereas HUVEC and venular junctions use vascular endothelial-cadherin. PMID: 23288152 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - January 3, 2013 Category: Cardiology Authors: Kluger MS, Clark PR, Tellides G, Gerke V, Pober JS Tags: Arterioscler Thromb Vasc Biol Source Type: research
Increased Interstitial Protein Because of Impaired Lymph Drainage Does Not Induce Fibrosis and Inflammation in Lymphedema.
CONCLUSIONS: Our data suggest that a high interstitial protein concentration and longstanding edema is not sufficient to induce fibrosis and inflammation characteristic for the human condition and may have implications for our understanding of the pathophysiology of this condition. PMID: 23288156 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - January 3, 2013 Category: Cardiology Authors: Markhus CE, Karlsen TV, Wagner M, Svendsen OS, Tenstad O, Alitalo K, Wiig H Tags: Arterioscler Thromb Vasc Biol Source Type: research
Comparison of work-related ill-health data from different GB sources
Conclusions SWI is more inclusive than THOR-GP; however, reports are unsubstantiated by medical opinion. Clinical specialist reports are subject to biases such as severity and referral patterns. GP data benefit from their inclusion of less severe cases than reports from secondary care and may give a better reflection of the incidence of diseases with a work-related aetiology unrecognized by self-reporting individuals.
Source: Occupational Medicine - January 3, 2013 Category: Respiratory Medicine Authors: Hussey, L., Carder, M., Money, A., Turner, S., Agius, R. Tags: Original Paper Source Type: research
How to optimize HCV therapy in genotype 1 patients: management of side‐effects
Abstract Antiviral therapy for chronic hepatitis C has dramatically changed with the advent of triple therapy incorporating direct‐acting antivirals (DAAs) such as the protease inhibitors (PI) boceprevir and telaprevir. Such triple‐therapy is associated with a new spectrum of side‐effects which can hamper quality of life. These may lead to dosage reduction and sometimes discontinuation of therapy. This review presents practical tips to help manage adverse effects appropriately and efficiently. The main adverse effects causing discontinuation of therapy are varied. Although the most common adverse effects are the ‘f...
Source: Liver International - January 3, 2013 Category: Gastroenterology Authors: Angeli Chopra, Patricia L. Klein, Thia Drinnan, Samuel S. Lee Tags: Review Article Source Type: research
Composite‐Graft zur Nasenflügelkantenrekonstruktion
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Justinus A. Wagner, Michael Kendler, Jan C. Simon, Tino Wetzig Tags: Dermatochirurgie – Tricks of the Trade Source Type: research
Rote juckende Papeln mit narbiger Abheilung bei einem jungen, sonst gesunden Mann
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Christine Hallermann, Marc Oliver Bodendorf, Jan Christoph Simon, Regina Treudler Tags: Diagnosequiz Source Type: research
Erfolgreiche Behandlung von zwei Patienten mit multiläsionaler kutaner Leishmaniasis mit liposomalem Amphotericin
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Florian Butsch, Michael Faulde, Andrea Debus, Christian Bogdan, Esther von Stebut Tags: Clinical Letters Source Type: research
Beteiligung der Ohrläppchen bei chronischer lymphatischer Leukämie
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Triantafyllia Koletsa, Aikaterini Patsatsi, Ioannis Kostopoulos, Elisavet Georgiou, Dimitrios Sotiriadis Tags: Clinical Letters Source Type: research
Die kutane Tumorzelllast korreliert mit dem Überleben von Patienten mit Sézary‐Syndrom
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Nina Booken, Jan Peter Nicolay, Christel Weiss, Claus‐Detlev Klemke Tags: Originalarbeit Source Type: research
Inzision und Drainage vor definitiver Operation verringert die 20‐Jahres‐Langzeitrezidivrate in 583 Patienten mit primär operierter Steißbeinfistel
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Dietrich Doll, Edouard Matevossian, Christian Hoenemann, Sebastian Hoffmann Tags: Originalarbeit Source Type: research
Umgang mit Antikoagulation bei dermatochirurgischen Eingriffen in Deutschland – Ergebnisse einer Querschnittsstudie
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Alexander Nast, Henriette Ernst, Stefanie Rosumeck, Ricardo Erdmann, Birte Sporbeck, Joachim W. Fluhr Tags: Originalarbeit Source Type: research
,,Die juckende Hand”– wichtige Differenzialdiagnosen und Therapie
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Elke Weisshaar, Ursula Kallen, Melanie Weiß Tags: Review Source Type: research
Maligne epitheliale Tumoren: Teil II. Therapie und Prävention
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Ioannis Manousaridis, Martin Leverkus Tags: CME‐Artikel Source Type: research
Malignant epithelial tumors: Part II. Therapy and prevention
Summary A multitude of surgical and non‐surgical therapies are available to treat malignant epithelial tumors of the skin. The article summarizes the current treatment options for basal cell carcinoma, squamous cell carcinoma and keratoacanthoma. Moreover, the possibilities of primary and secondary prevention for high‐risk patients are reviewed. The decision about the best therapeutic option depends on location, age, and general health of the patient as well as the risk of tumor recurrence.
Source: JDDG - January 3, 2013 Category: Dermatology Authors: Ioannis Manousaridis, Martin Leverkus Tags: CME Article Source Type: research
Routine Skin Cancer Screening in Germany: Four Years of Experience from the Dermatologists’ Perspective
Source: Dermatology - January 2, 2013 Category: Dermatology Source Type: research
Ichthyosis keeps surprising us.
PMID: 23291016 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - January 2, 2013 Category: Dermatology Authors: Traupe H Tags: Actas Dermosifiliogr Source Type: research
Chronic radiodermatitis following percutaneous transluminal coronary angioplasty
Source: JDDG - January 2, 2013 Category: Dermatology Authors: Julia GarcÌa Reitbîck, Robert Feldmann, Kerstin Rühringer, Friedrich Breier, Andreas Steiner Tags: Clinical Letters Source Type: research
Brachioradial pruritus – descriptive analysis of Brazilian case series
Conclusions: Although uncommon, brachioradial pruritus should not be neglected in dermatological diagnosis. This case series analysis indicated that Brazilian patients from a tropical climate show characteristics similar to those described in other series from more temperate regions.
Source: JDDG - January 2, 2013 Category: Dermatology Authors: Paula Y. Masuda, Antonio Carlos Ceribelli Martelli, Patrick A. Wachholz, Hélcio T. Akumatsu, Ana L. G. P. Martins, Nathália M. Silva Tags: Original Article Source Type: research
Treatment of advanced cutaneous T‐cell lymphomas with non‐pegylated liposomal doxorubicin – Consensus of the lymphoma group of the Working Group Dermatologic Oncology
Conclusions: The clinical use of NPLD in the treatment of CTCL is reasonable. In analogy to the clinical trials of NPLD in non‐Hodgkin lymphoma a dosage of 50 mg/m2 every three weeks is recommended for the treatment of CTCL.
Source: JDDG - January 2, 2013 Category: Dermatology Authors: Chalid Assaf, Jürgen C. Becker, Marc Beyer, Antonio Cozzio, Edgar Dippel, Claus‐Detlev Klemke, Peter Kurschat, Michael Weichenthal, Rudolf Stadler Tags: Original Article Source Type: research
Alopecia areata during treatment with adalimumab: therapy with an alternative TNF‐alpha inhibitor is possible
Source: JDDG - January 2, 2013 Category: Dermatology Authors: Carolin Zschoche, Mona Bidier, Eva Hadaschik Tags: Clinical Letters Source Type: research
Wound‐associated macrophages control collagen 1α2 transcription during the early stages of skin wound healing
In conclusion, our results demonstrate an important role of wound macrophages in the control of collagen production during wound healing.
Source: Experimental Dermatology - January 2, 2013 Category: Dermatology Authors: Mathieu P. Rodero, Julien M. D. Legrand, George Bou‐Garios, Kiarash Khosrotehrani Tags: Letter to the Editor Source Type: research
The biodisposition and hypertrichotic effects of bimatoprost in mouse skin
Abstract Studies on bimatoprost were performed with two objectives: (i) to determine whether bimatoprost possesses hair growth‐stimulating properties beyond eyelash hypertrichosis and (ii) to investigate the biodisposition of bimatoprost in skin for the first time. Bimatoprost, at the dose used clinically for eyelash growth (0.03%) and given once daily for 14 days, increased pelage hair growth in C57/black 6 mice. This occurred as a much earlier onset of new hair growth in shaved mice and the time taken to achieve complete hair regrowth, according to photographic documentation and visual assessment. Bimatoprost biodispo...
Source: Experimental Dermatology - January 2, 2013 Category: Dermatology Authors: David F. Woodward, Elaine S.‐H. Tang, Mayssa Attar, Jenny W. Wang Tags: Letter to the Editor Source Type: research
Eliminating Hospital-Acquired Pressure Ulcers: Within Our Reach
This article provides data from the Collaborative Alliance for Nursing Outcomes (CALNOC) that shows a significant reduction in HAPUs in adults from 78 acute care hospitals over 8 years (2003–2010).
Source: Advances in Skin and Wound Care - January 1, 2013 Category: Dermatology Tags: Features: Original Investigations Source Type: research
Addressing the Educational Needs of Wound Care Professionals
No abstract available
Source: Advances in Skin and Wound Care - January 1, 2013 Category: Dermatology Tags: Departments: Needs Assessment Source Type: research
Serum eosinophil cationic protein level in Chinese subjects with nonallergic and local allergic rhinitis and its relation to the severity of disease.
CONCLUSION: The present study provides the first evidence that LAR exists in Chinese subjects. This study also suggests that eosinophils and ECP take part in the pathogenesis of NAR. A local examination for ECP and specific IgE in nasal lavage fluid or secretions in patients with LAR should be performed in a future study. PMID: 23406588 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Cheng KJ, Xu YY, Liu HY, Wang SQ Tags: Am J Rhinol Allergy Source Type: research
The development of allergic rhinitis in children previously diagnosed as nonallergic rhinitis.
CONCLUSION: Children with NAR who had family history of atopy, persistent nasal symptoms, and symptoms triggered by aeroallergens should be reevaluated periodically for the development of AR. This study was part of the clinical trial NCT01068808 registered in www.clinicaltrials.gov. PMID: 23406600 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Veskitkul J, Vichyanond P, Visitsunthorn N, Jirapongsananuruk O Tags: Am J Rhinol Allergy Source Type: research
Is There a Role for the Detection of Autoantibodies in the Clinical Practice of Treating Infants with Bullous Pemphigoid? A Case Report
We present a case of infantile bullous pemphigoid (BP) triggered by primary infection with varicella zoster virus and we analyze the correlation between autoantibody levels and disease activity. With this report we suggest that serum autoantibody titers may not necessarily mirror the clinical course of the disease or represent a helpful tool in guiding therapeutic decisions in infantile BP.
Source: Pediatric Dermatology - January 1, 2013 Category: Dermatology Authors: Valeria Brazzelli, Vincenzo Grasso, Grazia Bossi, Giovanni Borroni Tags: Brief Report Source Type: research
Adjunctive hyperbaric oxygen therapy in the treatment of thermal burns.
Abstract A significant and consistently positive body of evidence from animal and human studies of thermal injury support the use of hyperbaric oxygen as a means of preventing dermal ischemia, reducing edema, modulating the zone of stasis, preventing partial- to full-thickness conversion, preserving cellular metabolism and promoting of healing. The vast majority of clinical reports have shown reduction in mortality, length of hospital stay, number of surgeries and cost of care. Hyperbaric oxygen has been demonstrated to be safe in the hands of those thoroughly trained in rendering therapy in the critical care setti...
Source: Undersea and Hyperbaric Medicine - January 1, 2013 Category: Sports Medicine Authors: Cianci P, Slade JB, Sato RM, Faulkner J Tags: Undersea Hyperb Med Source Type: research
Aberrant epidermal expression of semaphorin 3A and nerve growth factor in prurigo nodularis
Source: The Journal of Dermatology - January 1, 2013 Category: Dermatology Authors: Shinnosuke TAKADA, Kenzen KOU, Yoji NAGASHIMA, Zenro IKEZAWA, Michiko AIHARA Tags: Letter to the Editor Source Type: research
Epidermolytic palmoplantar keratoderma caused by activation of a cryptic splice site in KRT9
Summary Epidermolytic palmoplantar keratoderma (EPPK) is caused by mutations in KRT9 and less often, KRT1. All known mutations in KRT9 have been found in regions of the gene encoding the conserved central α‐helix rod domain. In the present study, we investigated the molecular basis of EPPK in a patient of Ashkenazi Jewish origin. The patient was found to carry a novel missense mutation in KRT9, resulting in the substitution of a poorly conserved leucine for valine at position 11 of the amino acid sequence. Despite its unusual location, the mutation was shown to be pathogenic through activation of a cryptic donor splice ...
Source: Clinical And Experimental Dermatology - January 1, 2013 Category: Dermatology Authors: D. Fuchs‐Telem, G. Padalon‐Brauch, O. Sarig, E. Sprecher Tags: Experimental dermatology • Source Type: research
Vitiligo: the white armor?
The difficulty in the management of the patient with vitiligo is that long‐term UVB narrowband phototherapy is the recognized mainstay for treatment contrasting with the fact that dermatologists warn constantly their patients about the dangers of sun exposure to limit skin aging and cancer. Ambivalent reasoning has not a great appeal in the profession and many dermatologists just prefer to give vitiligo patients sunscreens for white skin and advice for reinforced photoprotection. In this context, the retrospective study by Teulings et al. in a Dutch population indicating that patients with vitiligo have a decreased risk ...
Source: Pigment Cell Research - January 1, 2013 Category: Cytology Authors: Alain Taïeb, Khaled Ezzedine Tags: News & Views Source Type: research