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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 4.

CD30+ reversible lymphoid dyscrasia (pseudolymphoma) following HIDA scintigraphy and the [Ring1]-[Ring2]-[C=O] generalized structure hypothesis
To the Editor: Eighteen days after hepatobiliary iminodiacetic acid (HIDA) scintigraphy, an 81-year-old woman presented with pruritic, painful, discrete, tender papules in a generalized distribution (). She noted onset of the eruption shortly after the HIDA scan. Biopsy specimen of 2 papules from the right thigh showed an infiltration of mitotically active lymphocytes (, top inset) confined to the upper dermis. The lymphocytes were predominantly CD3+ T cells; occasional scattered CD20+ B cells were present. CD4 and CD8 were present in an approximately 2:1 ratio, and both cell types were noted within the epidermis. Small ag...
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Ryan K. Rader, William V. Stoecker, Kristen A. Hinton, Janine C. Malone, Thomas P. Schuman Tags: JAAD Online Source Type: research

Acneiform eruptions associated with vemurafenib
To the Editor: Acneiform eruptions are follicular reactions composed of comedones and inflammatory papulopustules that simulate acne vulgaris but are most commonly induced by medications. Comedones secondary to ductal hypercornification and subsequent inflammation drive acne, whereas in acneiform reactions, inflammation triggers papule and pustule formation with comedones forming secondarily.
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Tatyana A. Petukhova, Roberto A. Novoa, Kord Honda, Henry B. Koon, Meg R. Gerstenblith Tags: JAAD Online Source Type: research

Long-standing coalescing yellowish papules on the neck
A 24-year-old previously healthy, pregnant white woman complained of dry skin and yellowish bumps on the neck of approximately 10 years’ duration. Blood work, including a complete blood cell count and basic metabolic panel were within normal limits. The physical examination revealed yellowish papules that coalesced into irregular linear plaques on the lateral aspect of the neck () and in the antecubital fossae. There was no skin laxity. Histopathologic examination of a skin biopsy specimen from the neck revealed irregular elastic fibers located in the superficial to mid-dermis, which stained pink-purple on hematoxylin–...
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Laurie Matt, Nairmeen Haller, Eliot Mostow Tags: Images in Dermatology Source Type: research

Exfoliative erythroderma in an 80-year-old man
An 80-year-old man presented with a 12-week history of a generalized pruritic skin eruption. The physical examination revealed diffuse erythema and scaling of the entire body with sparing of his face and palmoplantar surfaces (). A tense bulla was identified on the sole of his left foot (). He was otherwise well and had been taking colchicine for gout for several years. A laboratory study revealed a white blood cell count of 13,000 μL, of which 25% were eosinophils. A biopsy specimen revealed a subepidermal blister containing eosinophils and lymphocytes. Direct immunofluorescence studies are shown in (A, immunoglobulin G; B, complement 3).
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Yu-Ting Lin, Che-Yi Chou, I-Jing Chang Tags: Images in Dermatology Source Type: research

Dermatology Calendar
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Tags: Letters Source Type: research

Cost analysis suggests overemphasis on biopsy rate for melanoma diagnosis
To the Editor: The multiple studies that evaluate the biopsy rate per melanoma diagnosed, also referred to as the number needed to excise (NNE), reflect the emphasis on minimizing NNE in order to decrease the overall costs and morbidity of melanoma evaluation. The research necessary to establish a target or benchmark biopsy rate for melanoma diagnosis, however, has not been performed. I present a cost analysis of NNE in relation to person-years of life saved to contribute this essential perspective to the discussion of an appropriate biopsy rate for melanoma diagnosis.
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Stuart M. Goldsmith Tags: Research Letters Source Type: research

Topical antibiotic use following dermatologic procedures
In this study, we describe current dermatologists’ practices regarding use of topical antibiotics following procedures.
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Peggy A. Wu, Kenneth A. Katz, William D. James Tags: Research Letters Source Type: research

Skin scan: A demonstration of the need for FDA regulation of medical apps on iPhone
To the Editor: With the widespread use of electronic devices, it has become increasingly common for patients to seek medical advice through applications available in the App Store. Spot Check claims it will send images of your moles to a dermatologist for evaluation, WebLantis offers to teach you how to remove unsightly moles, and numerous apps claim to be able to analyze moles for their risk of evolving into or being a melanoma (Skin of Mine, Skin Prevention, Mole Detective 2, and Skin Scan). To investigate the potential danger of such apps, we searched the app store for “skin cancer” and the first app listed, Skin Sc...
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Natalie Anne Ferrero, Dean S. Morrell, Craig Nathaniel Burkhart Tags: Research Letters Source Type: research

Dermatology podcasting: An untapped resource for continuing education
To the Editor: Keeping up with the fast-paced environment of medicine and the latest medical research can prove challenging for dermatologists. Because of this, educational resources are becoming more accessible to increase the ease of continuing medical education. Daily e-mails conveying the latest research updates, educational webinars, and podcasts are all helping to make continuing medical education more efficient.
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Jill Henley, Mahsa Amir, Blake Sampson, Jennifer M. Tamai, Robert P. Dellavalle Tags: Research Letters Source Type: research

The protective effect of sunscreens, vitamin E 6% cream, and betamethasone 0.1% cream on solar-simulating radiation-induced erythema and neutrophil influx
To the Editor: Exposing skin to erythemogenic doses of solar-simulating radiation (SSR) results in an influx of neutrophils. Our group has previously shown that neutrophils are a major source of enzymatically active, photoaging-associated, proteolytic enzymes, and thereby appear to be important contributors to photoaging. Preventing neutrophils from infiltrating the skin after SSR exposure, therefore, should limit the amount of SSR-induced skin damage.
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Feiko Rijken, Ilse C. Bihari, Kees L.H. Guikers, Huib van Weelden, Piet L.B. Bruijnzeel Tags: Research Letters Source Type: research

Deficiency of serum concentration of 25-hydroxyvitamin D correlates with severity of disease in chronic plaque psoriasis
To the Editor: We read with interest the article by Orgaz-Molina et al regarding the vitamin D status in patients with chronic plaque psoriasis. The authors report a high prevalence (25.6%) of vitamin D deficiency [25(OH)D levels
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Federica Ricceri, Leonardo Pescitelli, Lara Tripo, Francesca Prignano Tags: Notes & Comments Source Type: research

Reply
To the Editor: We appreciate the comments submitted by Ponti and Longo in response to our article, ‘‘Sebaceous neoplasms with mismatch repair protein expressions and the frequency of co-existing visceral tumors.’’ They raise several interesting points. We are aware that solitary keratoacanthoma (KA) can be associated with Muir-Torre syndrome (MTS). However, since KA can have overlapping histologic features with invasive squamous cell carcinoma with keratoacanthomatous features, the diagnosis of KA was not made frequently in one of our institutions. Therefore we chose to study sebaceous tumors, diagnosis of which is...
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Dongsi Lu Tags: Notes & Comments Source Type: research

Microsatellite instability and mismatch repair protein expression in sebaceous tumors, keratocanthoma, and basal cell carcinomas with sebaceous differentiation in Muir-Torre syndrome
To the Editor: Recently the Journal of the American Academy of Dermatology featured an interesting article by Lee et al investigating the frequency of internal malignancies in patients with sebaceous tumors. We read this article with interest, and we would like to highlight some aspects and express the following concerns regarding this report:
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Giovanni Ponti, Caterina Longo Tags: Notes & Comments Source Type: research

The AIDS epidemic, then and now
As part of the celebration of the Academy's 75th anniversary, this year each monthly issue of JAAD features an expert commentary on a previously published article of particular significance to practicing dermatologists.
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Marcus A. Conant Tags: AAD 75th Anniversary Article Source Type: research

Announcing New Features in JAAD Online
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Tags: Continuing Medical Education Source Type: research

Answers to CME examination
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Tags: Continuing Medical Education Source Type: research

Change of Address
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Tags: Continuing Medical Education Source Type: research

CME examination
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Tags: Continuing Medical Education Source Type: research

Compassionate care: Enhancing physician–patient communication and education in dermatology: Part II: Patient education
Patient education is a fundamental part of caring for patients. A practice gap exists, where patients want more information, while health care providers are limited by time constraints or difficulty helping patients understand or remember. To provide patient-centered care, it is important to assess the needs and goals, health beliefs, and health literacy of each patient. This allows health care providers to individualize education for patients. The use of techniques, such as gaining attention, providing clear and memorable explanations, and assessing understanding through “teach-back,” can improve patient education. Ve...
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Judith Hong, Tien V. Nguyen, Neil S. Prose Tags: Continuing Medical Education Source Type: research

CME examination
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Tags: Continuing Medical Education Source Type: research

American Board of Dermatology Examination Dates
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Tags: Continuing Medical Education Source Type: research

Compassionate care: Enhancing physician–patient communication and education in dermatology: Part I: Patient-centered communication
The motivation for developing patient-centered communication stems from a desire to enhance the quality of patient care, fulfill professional competency requirements, reduce medical errors, and improve health outcomes and patient satisfaction. Patient-centered communication skills can optimize the physician–patient relationship without significantly prolonging office visits. We propose a series of practical and generally effective techniques for verbal and nonverbal communication. We also suggest a targeted approach for specific difficult conversations that may occur frequently in the practice of dermatology.
Source: Journal of the American Academy of Dermatology - February 11, 2013 Category: Dermatology Authors: Tien V. Nguyen, Judith Hong, Neil S. Prose Tags: Continuing Medical Education Source Type: research

Health-Related Quality of Life, Patient Satisfaction, and Adherence to Treatment in Patients With Moderate or Severe Atopic Dermatitis on Maintenance Therapy: The CONDA-SAT Study.
CONCLUSIONS: Patients with moderate and severe AD receiving maintenance therapy experience a reduction in the number and duration of flares and an improvement in HRQOL. While treatment satisfaction is high, adherence rates could be improved. PMID: 23411041 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - February 11, 2013 Category: Dermatology Authors: Torrelo A, Ortiz J, Alomar A, Ros S, Pedrosa E, Cuervo J Tags: Actas Dermosifiliogr Source Type: research

[Use of Matriderm(®) 1mm in reconstructive surgery. Series of 31 cases.]
CONCLUSIONS: Matriderm(®) 1mm, dermal substitute commonly used in acute burn treatment can be indicated in reconstructive surgery. This series show that it permits to obtain a good graft taken rate, a quick healing with a satisfying aesthetic and functional results and permit an early discharge. However, its indications are limited by its cost. PMID: 23410720 [PubMed - as supplied by publisher]
Source: Annales de Chirurgie Plastique et Esthetique - February 11, 2013 Category: Cosmetic Surgery Authors: Lamy J, Gourari A, Atlan M, Zakine G Tags: Ann Chir Plast Esthet Source Type: research

Association of Denervation Severity in the Dermis with the Development of Mechanical Allodynia and Hyperalgesia in a Murine Model of Postherpetic Neuralgia.
CONCLUSIONS:The present results suggest that the severity of dermal denervation in the scarred skin is associated with the development of postherpetic allodynia and hyperalgesia that extend beyond the margins of the initial rash area. The decrease of epidermal nerve density in the scarred and stimulation skins may not be associated with postherpetic allodynia and hyperalgesia. PMID: 23400987 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - February 11, 2013 Category: Anesthesiology Authors: Inomata Y, Gouda M, Kagaya K, Yamagami K, Sasaki A, Andoh T, Kuraishi Y Tags: Anesth Analg Source Type: research

Does filaggrin expression correlate with severity of clinical signs in dogs with atopic dermatitis?
CONCLUSIONS AND CLINICAL IMPORTANCE: No inverse correlation exists between the severity of clinical signs and filaggrin expression; the clinical relevance of filaggrin in canine AD is unknown. PMID: 23398596 [PubMed - as supplied by publisher]
Source: Veterinary Dermatology - February 11, 2013 Category: Veterinary Research Authors: Marsella R Tags: Vet Dermatol Source Type: research

A keratoma horn following deep brain stimulation
An 84-year-old man underwent deep brain stimulation (DBS) for mixed rest-action tremors. One year later, he developed a keratoma where the DBS wire emerged from the insertion cap. It was suspected to be a foreign body reaction and removed by a dermatologist but returned and grew conically over the next 4 years, reaching a height of 4 cm (figure). The surrounding skin began to break down with protrusion of the adjacent extension wire. We recommended removal of the lead but due to continued efficacy and advanced age, he decided to continue with the stimulator in place under observation.
Source: Neurology - February 11, 2013 Category: Neurology Authors: Pourfar, M., Mogilner, A., Mammis, A., Goodman, R. Tags: Parkinson's disease/Parkinsonism, Tremor, Surgery/Stimulation NEUROIMAGE Source Type: research

The sound of silence: autosomal recessive congenital ichthyosis caused by a synonymous mutation in ABCA12
We report a consanguineous family of Arab Muslim origin with several members displaying a severe form of congenital ichthyosiform erythroderma. Using a panel of polymorphic microsatellite markers, we identified a region of homozygosity shared by all patients on 2q34, in a region harboring the ABCA12 gene. Direct sequencing of genomic DNA derived from a patient failed to reveal any obviously pathogenic change in the coding sequence of this gene. In contrast, cDNA sequence analysis revealed the existence of a 163 bp long deletion in exon 24, thus pointing to a splicing defect. Careful reanalysis of the genomic DNA sequence r...
Source: Experimental Dermatology - February 11, 2013 Category: Dermatology Authors: T. Goldsmith, D. Fuchs‐Telem, S. Israeli, O. Sarig, G. Padalon‐Brauch, R. Bergman, M. Indelman, E. Sprecher, J. Nousbeck Tags: Regular Article Source Type: research

E‐FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro
Abstract Epidermal fatty acid‐binding protein (E‐FABP) is a lipid carrier, originally discovered in human epidermis. We show that E‐FABP is almost exclusively expressed in post mitotic (PM) keratinocytes, corresponding to its localization in the highest suprabasal layers, while it is barely expressed in keratinocyte stem (KSC) and transit amplifying (TA) keratinocytes. Transfection of normal human keratinocytes with recombinant (r) E‐FABP induces overexpression of K10 and involucrin. On the other hand, E‐FABP inhibition by siRNA downregulates K10 and involucrin expression in normal keratinocytes through NF‐κB ...
Source: Experimental Dermatology - February 11, 2013 Category: Dermatology Authors: K Dallaglio, A Marconi, F Truzzi, R Lotti, E Palazzo, T Petrachi, A Saltari, M Coppini, C Pincelli Tags: Regular Article Source Type: research

Imbalance of intermediate filament component keratin 14 contributes to increased stress signaling in epidermolysis bullosa simplex
Abstract An important characteristic of epidermolysis bullosa simplex Dowling‐Meara (EBS‐DM) keratinocytes is the increased level of Jun N‐terminal kinase (JNK) stress‐signaling, which is thought to contribute to the disease phenotype. In this work, we report on the dramatic up‐regulation of cytokeratin 14 (K14) in the EBS‐DM model cell line KEB7 at both the transcriptional and translational levels, which is noteworthy because KEB7 patient cells are heterozygous for a missense mutation (R125P) in K14. By performing functional assays we show a direct link between overexpressed wild‐type K14 and increased JNK�...
Source: Experimental Dermatology - February 11, 2013 Category: Dermatology Authors: Martin Wagner, Andrea Trost, Helmut Hintner, Johann W. Bauer, Kamil Onder Tags: Letter to the Editors Source Type: research

Approach towards developing a novel procedure to selectively quantify topically applied substances in the hair follicles of the model tissue porcine ear skin
Abstract Hair follicles represent reservoirs for localized drug therapy and transport pathways for systemic drug delivery. The present work describes an approach towards developing a novel procedure for quantifying topically applied substances located in the hair follicles of porcine ear skin, a model for human in vivo skin, using a fluorescent dye. Approximately 5% of the topically applied dye was recovered from the hair follicles, which is an accordance with a previous study.
Source: Experimental Dermatology - February 11, 2013 Category: Dermatology Authors: F. Knorr, A. Patzelt, H. Richter, S. Schanzer, W. Sterry, J. Lademann Tags: Methods Letter to the Editors Source Type: research

Staphylococcus aureus subverts cutaneous defense by D‐alanylation of teichoic acids
Abstract The gram‐positive bacterium Staphylococcus aureus is a frequent skin colonizer which often causes severe skin infections. It has been reported that neutralizing the negatively charged bacterial surface through the incorporation of D‐alanine in its lipoteichoic acids confers reduced susceptibility of S. aureus towards cationic antimicrobial peptides (AMP). Using a S. aureus strain deficient in D‐alanylated teichoic acids (dltA mutant) we demonstrate that D‐alanylation of its surface reduces the susceptibility of S. aureus to skin‐derived AMP such as RNase 7 and human beta‐defensins. This is accompanied ...
Source: Experimental Dermatology - February 11, 2013 Category: Dermatology Authors: M. Simanski, R. Gläser, B. Köten, U. Meyer‐Hoffert, Stefanie Wanner, Christopher Weidenmaier, A. Peschel, J. Harder Tags: Letter to the Editors Source Type: research

YKL‐40 is a serum biomarker reflecting the severity of cutaneous lesions in psoriatic arthritis
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Yasutomo Imai, Seiko Aochi, Keiji Iwatsuki, Hajime Sano, Kiyofumi Yamanishi Tags: Letter to the Editor Source Type: research

Spontaneous multiple eruptive milia in a 91‐year‐old man
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Yuta Kurashige, Tetsuo Nagatani Tags: Letter to the Editor Source Type: research

Epiplakin modifies the motility of the HeLa cells and accumulates at the outer surfaces of 3‐D cell clusters
Abstract Elimination of epiplakin (EPPK) by gene targeting in mice results in acceleration of keratinocyte migration during wound healing, suggesting that epithelial cellular EPPK may be important for the regulation of cellular motility. To study the function of EPPK, we developed EPPK knock‐down (KD) and EPPK‐overexpressing HeLa cells and analyzed cellular phenotypes and motility by fluorescence/differential interference contrast time‐lapse microscopy and immunolocalization of actin and vimentin. Cellular motility of EPPK‐KD cells was significantly elevated, but that of EPPK‐overexpressing cells was obviously de...
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Hiromitsu Shimada, Akiko Nambu‐Niibori, Masayo Wilson‐Morifuji, Souhei Mizuguchi, Norie Araki, Hideaki Sumiyoshi, Mitsuru Sato, Yoshihiro Mezaki, Haruki Senoo, Kazushi Ishikawa, Yutaka Hatano, Osamu Okamoto, Sakuhei Fujiwara Tags: Original Article Source Type: research

NEMO gene rearrangement (exon 4–10 deletion) and genotype–phenotype relationship in Japanese patients with incontinentia pigmenti and review of published work in Japanese patients
Abstract Incontinentia pigmenti (IP) is a rare X‐linked dominant genodermatosis caused by mutations of the NEMO gene, which is required for activation of the nuclear factor‐κB signaling pathway. NEMO gene rearrangement, exon 4–10 deletion, is the most common mutation with a frequency of 60–80%. Only four case reports about NEMO rearrangement in Japanese IP cases have been published. In our study, NEMO gene rearrangement was examined in 10 Japanese IP patients and their mothers and was revealed in five of 10 patients and three of their mothers. Interestingly, NEMO gene rearrangement was confirmed in the mothers of ...
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Mayuko Okita, Gen Nakanishi, Noriki Fujimoto, Mariko Shiomi, Taku Yamada, Mari Wataya‐Kaneda, Chincho Takijiri, Yoko Yokoyama, Akiyo Sunohara, Toshihiro Tanaka Tags: Case Report Source Type: research

Pustular eruption induced by sorafenib in a case of psoriasis vulgaris
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Nobuki Maki, Mayumi Komine, Yuka Takatsuka, Takeo Maekawa, Satoru Murata, Mamitaro Ohtsuki Tags: Letter to the Editor Source Type: research

Allergic contact dermatitis due to epsilon‐aminocaproic acid: A case report and mini‐review of the published work
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Yuriko Yamamoto, Makoto Wada, Noriaki Nakai, Norito Katoh Tags: Letter to the Editor Source Type: research

Therapeutic preferences are different in psoriatic and atopic dermatitis patients: A questionnaire‐based study
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Kotaro Ito, Shinichi Imafuku, Juichiro Nakayama Tags: Letter to the Editor Source Type: research

Case of paraneoplastic pemphigus with follicular lymphoma treated with rituximab
Source: The Journal of Dermatology - February 11, 2013 Category: Dermatology Authors: Jun Aoi, Katsunari Makino, Keisuke Sakai, Shinichi Masuguchi, Satoshi Fukushima, Masatoshi Jinnin, Yuji Inoue, Hiroshi Koga, Takashi Hashimoto, Hironobu Ihn Tags: Letter to the Editor Source Type: research

Sleep disturbances in psoriasis.
CONCLUSIONS: Patients with psoriasis suffer from sleep disturbances and pruritus more than those without psoriasis. Although sleep disturbances are more prevalent, this may be secondary to depression rather than related to a direct effect of psoriasis. PMID: 23374943 [PubMed - in process]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Shutty BG, West C, Huang KE, Landis E, Dabade T, Browder B, O'Neill J, Kinney MA, Feneran AN, Taylor S, Yentzer B, McCall WV, Fleischer AB, Feldman SR Tags: Dermatol Online J Source Type: research

Radiation-induced angiosarcoma.
CONCLUSION: We recommend that new skin lesions within or adjacent to radiation ports should be considered for biopsy. Also, for lesions that are larger, ill-defined, or both, several sites should be sampled to ensure an accurate diagnosis and to prevent the possibility of a false negative interpretation. PMID: 23374944 [PubMed - in process]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Anzalone CL, Cohen PR, Diwan AH, Prieto VG Tags: Dermatol Online J Source Type: research

Solitary congenital self-healing Langerhans cell histiocytosis: A benign variant of Langerhans cell histiocytosis?
We present two cases of solitary CSH-LCH (sCSH-LCH) and highlight certain unique characteristics including the favorable prognosis and lack of documented progression to systemic involvement in reported cases. PMID: 23374945 [PubMed - in process]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Yurkovich M, Wong A, Lam JM Tags: Dermatol Online J Source Type: research

Supernumerary nipple and seminoma: Case report and review of polythelia and genitourinary cancers.
We describe a 53-year-old man with an accessory nipple on the left chest who presented with stage IIA testicular seminoma at the age of 47. Published reports of patients with polythelia and genitourinary malignancies, as well as other neoplasms, are reviewed. Because patients with accessory nipples have a predisposition to develop visceral cancers, polythelia should be considered as a genodermatosis with malignant potential. PMID: 23374946 [PubMed - in process]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Grimshaw EC, Cohen PR Tags: Dermatol Online J Source Type: research

Primary cutaneous adenoid cystic carcinoma: An unusual case.
We present a case of primary adenoid cystic carcinoma in a young woman located on the skin of the upper limb, which is an unusual place. PMID: 23374947 [PubMed - as supplied by publisher]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Lestouquet FR, Sánchez Moya AI, Guerra SH, Cardona Alzate CJ Tags: Dermatol Online J Source Type: research

[Ross syndrome in a 38-year-old male].
We present a case of Ross Syndrome in a 38-year-old male with heat intolerance, which interfered with his daily work practice. PMID: 23374948 [PubMed - in process]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Pérez-García P, Bernat-García J, Mateu-Puchades A Tags: Dermatol Online J Source Type: research

Clopidogrel-associated vasculopathic cutaneous reaction.
We present a case report of a man who experienced vascular thromboses, which subsequently resolved following discontinuation of clopidogrel. PMID: 23374949 [PubMed - in process]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Fathi R, Shamma HN, Fathi A Tags: Dermatol Online J Source Type: research

The evolution of clinicopathologic features in eruptive lichen planus: A case report and review of literature.
Abstract "Eruptive" or "exanthematous" lichen planus (LP) is a rare variant of lichen planus. Here we report a middle-aged woman with a 6-month history of episodic eruptive LP presenting as generalized, erythematous, flat-topped, round, polygonal, or umbilicated papules and hyperpigmented macules. The disease was under good control with continuous low-dose prednisolone over one year. We had the opportunity to correlate the clinical and pathologic findings based on histopathologic examination of three separate skin lesions that appeared to represent different stages of evolution. Recognition of these 3 chronological...
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Liu KC, Lee JY, Hsu MM, Hsu CK Tags: Dermatol Online J Source Type: research

Exogenous insulin-derived acanthosis nigricans: Could it be a cause of increased insulin requirement?
Abstract Acanthosis nigricans is a cutaneous manifestation of insulin resistance. We herein present a case of localized acanthosis nigricans over the abdomen in a 14-year-old boy with type 1 diabetes mellitus. The acanthosis nigricans appeared secondary to repeated insulin injection over same site. After advising the patient about rotating the injection site there was better disease control along with drop in insulin requirement and a significant reduction in the size of the lesion. PMID: 23374951 [PubMed - in process]
Source: Dermatol Online J - February 10, 2013 Category: Dermatology Authors: Dhingra M, Garg G, Gupta M, Khurana U, Thami GP Tags: Dermatol Online J Source Type: research