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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 5.

Patient‐reported outcome measures in nonmelanoma skin cancer of the face: a systematic review
Summary Nonmelanoma skin cancer (NMSC) is the most common malignancy in the western world, with an incidence of 98 000 in the U.K. Since 2009 the Department of Health (DoH) has collected patient‐reported outcome measure (PROM) data following four common surgical procedures. However, a DoH PROM for NMSC does not exist. A systematic review of questionnaires published on patient concerns due to NMSC of the face was conducted. Keywords relevant to PROMs, NMSC and the facial region were comprehensively searched in medical databases. Inclusion criteria stipulated questionnaires from relevant papers that recruited patients wit...
Source: British Journal of Dermatology - February 6, 2013 Category: Dermatology Authors: A.S. Bates, C.R. Davis, A. Takwale, G.J. Knepil Tags: Review Article Source Type: research

Synthesis of (cinnamate-zinc layered hydroxide) intercalation compound for sunscreen application
Conclusions: (Cinnamate-zinc layered hydroxide) intercalation compound is suitable to be used as a safe and effective sunscreen with long UV protection effect.
Source: Chemistry Central Journal - February 6, 2013 Category: Chemistry Authors: Sumaiyah MohsinMohd HusseinSiti SarijoSharida FakuraziPalanisamy ArulselvanTaufiq-Yap Hin Source Type: research

21st-Century Alternatives to Classic Resurfacing Techniques.
PMID: 23395529 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - February 5, 2013 Category: Dermatology Authors: Pérez-García B Tags: Actas Dermosifiliogr Source Type: research

Evaluation of Surgical Margins in Basal Cell Carcinoma by Surgical Specialty.
CONCLUSIONS: Accurate macroscopic identification of tumor margins, which are often difficult to see, and familiarity with the natural history of BCC are key factors in the successful surgical treatment of BCCs. The higher rate of tumor-free margins achieved by dermatologists in this study is probably mainly due to their greater experience in these 2 areas. PMID: 23395530 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - February 5, 2013 Category: Dermatology Authors: Bassas P, Hilari H, Bodet D, Serra M, Kennedy FE, García-Patos V Tags: Actas Dermosifiliogr Source Type: research

Dog and Cat Exposures to Hazardous Substances Reported to the Kansas State Veterinary Diagnostic Laboratory: 2009-2012.
Abstract Pet dogs and cats in the USA are commonly exposed to potentially hazardous substances found in domestic environments. Requests for assistance and advice received by the Kansas State Veterinary Diagnostic Laboratory regarding exposures in dogs and cats to substances perceived by their caretakers to be potentially harmful included 1,616 phone calls, over a 3-year period covering 2009-2012. Enquiries occurred more often during summer. Dogs were involved in 84.7 % of calls and cats in 15.3 %. Oral exposures were reported in 95.5 % of calls, dermal exposures in 3.7 % of calls, inhalation exposures in 0.6 %...
Source: Journal of Medical Toxicology - February 5, 2013 Category: Toxicology Authors: Mahdi A, Van der Merwe D Tags: J Med Toxicol Source Type: research

Esophageal human beta-defensin expression in eosinophilic esophagitis.
Conclusion:Diminished expression of hBD1 and hBD3 may make the esophageal epithelium more susceptible to the development and/or perpetuation of EoE.Pediatric Research (2013); doi:10.1038/pr.2013.23. PMID: 23385963 [PubMed - as supplied by publisher]
Source: Pediatric Research - February 5, 2013 Category: Pediatrics Authors: Schroeder S, Robinson ZD, Masterson JC, Hosford L, Moore W, Pan Z, Harris R, Souza RF, Spechler SJ, Fillon SA, Furuta GT Tags: Pediatr Res Source Type: research

Why does allergic contact dermatitis exist?
Abstract The skin immune system's propensity to produce allergic contact dermatitis (ACD) to harmless chemicals, whilst otherwise being an efficient defence system, represents a dermatological paradox. We postulate that a major role in signaling in ACD is played by Toll-like receptor (TLR) 2 and TLR4 that arises from their activation by extracellular DAMPs (danger associated molecular patterns). Ligand activation of TLR4/2 results in the expression of interleukins (IL) IL-1β, IL-6, IL-12, IL-18 and IL-23, tumour necrosis factor-α (TNF-α) and interferon-α (IFN-α). These cytokines promote acquisition of sensitis...
Source: The British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: McFadden JP, Puangpet P, Basketter DA, Dearman RJ, Kimber I Tags: Br J Dermatol Source Type: research

Acne severity and itch are associated: results from a Norwegian survey of 3775 adolescents.
Abstract Acne and itch(1) are highly associated with stress, but the relationship between acne and itch is not defined. Two small studies showed itch to be common among acne patients in Singapore(2) and Poland(3) . The aim of this study was to examine the association between acne severity and itch in a large sample of adolescents from the general population. This was a cross-sectional and questionnaire-based study, conducted at the University of Oslo with the Norwegian Institute of Public Health and the Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway. The study methods are previo...
Source: The British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: Dalgard F, Halvorsen JA, Kwatra SG, Yosipovitch G Tags: Br J Dermatol Source Type: research

Refractory cutaneous angiosarcoma successfully treated with sunitinib.
Abstract Angiosarcomas, one of the rare and aggressive tumours, are malignant vascular tumours that comprise only approximately 2% of all soft tissue sarcomas.(1) Cutaneous angiosarcoma is the most common type of these malignancies, with head and neck regions most often affected.(2) However, the outcome of such patients are very poor, with 5-year disease-free survival rate and 5-year survival rate less than 50% and 10-20%, respectively.(3) Surgery combined with radiation therapy is the optimal approach to eradicate the primary tumour.(4) Doxorubicin- or paclitaxel- based chemoregimens also reveal clinical benefit f...
Source: The British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: Lu HJ, Chen PC, Yen CC, Hsiao FC, Tzeng CH, Ma H, Shiau CY, Chao TC Tags: Br J Dermatol Source Type: research

Evaluation tool for children with subjective symptoms of eczema: Does the lack of correlation between several scale scores of eczema and percent of moving in the night by actigraphy leads to abandon the use of activity monitoring?
Abstract Wootton et al. reported on outcomes from a randomized controlled trial on the validity and acceptability of actigraphy for the measurement of disease severity in children with eczema.(1) Target patients were recruited from the Softened Water Eczema Trial, and three standardized questionnaires relating to dermatitis were adopted convergent and divergent validity assessment. The mean age of 235 patients was 5.7 years, and questionnaire survey was conducted or assisted by parents. PMID: 23383966 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: Kawada T Tags: Br J Dermatol Source Type: research

Actigraphy for children with eczema.
Abstract Dr Kawada raises several concerns regarding our paper. Our study used data generated through the randomized controlled Softened Water Eczema Trial, and we aimed to specifically evaluate how useful actigraphy is as an outcome measure in clinical trials that are evaluating response to treatment. Therefore actigraphy data would have had to correlate with other, already validated outcome measures as well as demonstrate responsiveness to changes in disease activity to prove useful in our stated context. PMID: 23384001 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: Wootton C, Thomas K Tags: Br J Dermatol Source Type: research

A case of pili torti in a young adult domestic short-haired cat.
CONCLUSIONS AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is the first case report of pili torti in a healthy young adult cat. PMID: 23384010 [PubMed - as supplied by publisher]
Source: Veterinary Dermatology - February 5, 2013 Category: Veterinary Research Authors: Maina E, Colombo S, Abramo F, Pasquinelli G Tags: Vet Dermatol Source Type: research

Why does allergic contact dermatitis exist?
Abstract The skin immune system's propensity to produce allergic contact dermatitis (ACD) to harmless chemicals, whilst otherwise being an efficient defence system, represents a dermatological paradox. We postulate that a major role in signaling in ACD is played by Toll‐like receptor (TLR) 2 and TLR4 that arises from their activation by extracellular DAMPs (danger associated molecular patterns). Ligand activation of TLR4/2 results in the expression of interleukins (IL) IL‐1β, IL‐6, IL‐12, IL‐18 and IL‐23, tumour necrosis factor‐α (TNF‐α) and interferon‐α (IFN‐α). These cytokines promote acquisition...
Source: British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: J.P. McFadden, P. Puangpet, D.A. Basketter, R.J. Dearman, I. Kimber Tags: Review Article Source Type: research

Acne severity and itch are associated: results from a Norwegian survey of 3775 adolescents
Abstract Acne and itch1 are highly associated with stress, but the relationship between acne and itch is not defined. Two small studies showed itch to be common among acne patients in Singapore2 and Poland3. The aim of this study was to examine the association between acne severity and itch in a large sample of adolescents from the general population. This was a cross‐sectional and questionnaire‐based study, conducted at the University of Oslo with the Norwegian Institute of Public Health and the Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway. The study methods are previously descri...
Source: British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: F. Dalgard, J.A. Halvorsen, S.G. Kwatra, G. Yosipovitch Tags: Correspondence Source Type: research

Refractory cutaneous angiosarcoma successfully treated with sunitinib
Abstract Angiosarcomas, one of the rare and aggressive tumours, are malignant vascular tumours that comprise only approximately 2% of all soft tissue sarcomas.1 Cutaneous angiosarcoma is the most common type of these malignancies, with head and neck regions most often affected.2 However, the outcome of such patients are very poor, with 5‐year disease‐free survival rate and 5‐year survival rate less than 50% and 10‐20%, respectively.3 Surgery combined with radiation therapy is the optimal approach to eradicate the primary tumour.4 Doxorubicin‐ or paclitaxel‐ based chemoregimens also reveal clinical benefit for t...
Source: British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: H.‐J. Lu, P.C.‐H. Chen, C.‐C. Yen, F.‐C. Hsiao, C.‐H. Tzeng, H. Ma, C.‐Y. Shiau, T.‐C. Chao Tags: Correspondence Source Type: research

Evaluation tool for children with subjective symptoms of eczema: Does the lack of correlation between several scale scores of eczema and percent of moving in the night by actigraphy leads to abandon the use of activity monitoring?
Wootton et al. reported on outcomes from a randomized controlled trial on the validity and acceptability of actigraphy for the measurement of disease severity in children with eczema.1 Target patients were recruited from the Softened Water Eczema Trial, and three standardized questionnaires relating to dermatitis were adopted convergent and divergent validity assessment. The mean age of 235 patients was 5.7 years, and questionnaire survey was conducted or assisted by parents.
Source: British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: T. Kawada Tags: Correspondence Source Type: research

Actigraphy for children with eczema
Dr Kawada raises several concerns regarding our paper. Our study used data generated through the randomized controlled Softened Water Eczema Trial, and we aimed to specifically evaluate how useful actigraphy is as an outcome measure in clinical trials that are evaluating response to treatment. Therefore actigraphy data would have had to correlate with other, already validated outcome measures as well as demonstrate responsiveness to changes in disease activity to prove useful in our stated context.
Source: British Journal of Dermatology - February 5, 2013 Category: Dermatology Authors: C. Wootton, K. Thomas Tags: Correspondence Source Type: research

Whole microvascular unit deletions in dermatomyositis
Conclusions Capillary loss may not be the primary cause of muscle ischaemia in DM. The primary event rather stands upstream, probably at the level of perimysial arcade arteries around which inflammatory infiltrates predominate and which lumen may show narrowing in chronic DM. Ischaemia-reperfusion injury, which is favoured by autoimmune backgrounds in experimental models and which activates the complement cascade in capillaries, could represent an hitherto unsuspected (and potentially preventable) mechanism of muscle damage in DM.
Source: Annals of the Rheumatic Diseases - February 5, 2013 Category: Rheumatology Authors: Gitiaux, C., Kostallari, E., Lafuste, P., Authier, F.-J., Christov, C., Gherardi, R. K. Tags: Immunology (including allergy), Muscle disease, Radiology, Connective tissue disease, Musculoskeletal syndromes, Clinical diagnostic tests Basic and translational research Source Type: research

Efficacy of anti-IL-1 treatment in Majeed syndrome
Conclusions The differential response to treatment with TNF-α or IL-1 blocking agents sheds light into disease pathogenesis; it supports the hypothesis that Majeed syndrome is an IL-1β dependent autoinflammatory disorder, and further underscores the importance of IL-1 in sterile bone inflammation.
Source: Annals of the Rheumatic Diseases - February 5, 2013 Category: Rheumatology Authors: Herlin, T., Fiirgaard, B., Bjerre, M., Kerndrup, G., Hasle, H., Bing, X., Ferguson, P. J. Tags: Genetics, Immunology (including allergy), Bone and joint infections, Inflammation, Musculoskeletal syndromes, Epidemiology, Calcium and bone Clinical and epidemiological research Source Type: research

Differences in fungi present in induced sputum samples from asthma patients and non-atopic controls: a community based case control study
Conclusion: This study is novel in providing evidence for the widespread nature of fungi in the sputum of healthy and asthmatic individuals. Differences in the pattern of fungi present in asthma patients and controls merit further investigation. Of particular interest was the presence of Malassezia pachydermatis, which is known to be associated with atopic dermatitis.
Source: BMC Infectious Diseases - February 5, 2013 Category: Infectious Diseases Authors: Hugo van WoerdenClive GregoryRichard BrownJulian MarchesiBastiaan HoogendoornIan Matthews Source Type: research

Management of sexual dysfunction due to vulvar lichen sclerosus in postmenopausal women
Abstract Lichen sclerosus is a chronic skin disease, probably immune‐mediated, with a strong genetic component. It shows a predilection for external genitalia. It is most common in postmenopausal women, although it has been documented at all ages and in both sexes. The exact prevalence of lichen sclerosus is unknown. However, in recent years much progress has been made in defining its etiology and epidemiology, and we now know that it is far more frequent than previously thought. The purpose of this review is to focus more attention on the relationship between LS and sexual dysfunction, and on a few important aspects of ...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: Sara Pinelli, Angelo Massimiliano D'Erme, Torello Lotti Tags: Therapeutic Hotline Source Type: research

Treatment of severe nail psoriasis with acitretin: an impressive therapeutic result
Abstract Nail psoriasis is common in adult psoriatic patients. Although several new drugs have recently been introduced for the treatment of skin psoriasis, treatment of nail psoriasis still remains a challenge. Topical treatments (e.g., corticosteroids, tazarotene, 5‐fluorouracil, calcipotriol) are the first line in the management of skin psoriasis. The efficacy of these drugs in nail disease, however, is limited, mainly due to the difficulty in penetrating the nail bed and nail matrix. In cases of nail disease resistant to topical treatment, methotrexate, ciclosporin, acitretin, or biological agents can be used. The pr...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: F. Ricceri, L. Pescitelli, L. Tripo, A. Bassi, F. Prignano Tags: Therapeutic Hotline Source Type: research

Etanercept‐induced Wegener granulomatosis in a patient with rheumatoid arthritis
Abstract A very rare case of etanercept‐induced Wegener's granulomatosis in a patient with long‐standing rheumatoid arthritis is reported. A thorough critical analysis on Wegener's granulomatosis pathogenetic mechanisms is done. The peculiarities of etanercept pharmacodynamic features are also presented together with some suggestions of possible induction pathways.
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: Valentina Broshtilova, Emil Iliev, Mary Gantcheva Tags: Therapeutic Hotline Source Type: research

Successful treatment of hydroquinone‐resistant melasma using topical methimazole
Abstract Melasma is an acquired hyperpigmentation skin disorder in sun‐exposed areas. It occurs almost exclusively over the face, and is most commonly seen in women. Several depigmenting agents have been used for the treatment of melasma among which hydroquinone has been the most widely used due to its efficacy and safety in short‐term use. However, hydroquinone is recently reported to be a cytotoxic and mutagenic compound in mammalian cells and is thus banned in several countries. Hydroquinone ban has caused investigators to search for alternative depigmenting agents for the treatment of melasma in recent years. Methi...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: Joelle Malek, Adele Chedraoui, Damian Nikolic, Neda Barouti, Samer Ghosn, Ossama Abbas Tags: Therapeutic Hotline Source Type: research

Management of ichthyosis and related conditions gene‐based diagnosis and emerging gene‐based therapy
Abstract Knowledge of the molecular basis of many inherited diseases has grown exponentially during the past decade. Inherited skin diseases, including the ichthyoses and related conditions, benefited from that explosion of information, much of which has relevance for the clinical setting. In this section, the authors review the genes now known to be involved in ichthyosis, the methods for detecting mutations in those genes in the clinical diagnostic laboratory, options for using that information for diagnosis and pregnancy/family planning decisions, and current and future therapies based on the knowledge of the molecular ...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: Gabriele Richard, Keith Choate, Leonard Milstone, Sherri Bale Tags: Invited Article Source Type: research

Pathogenesis‐based therapies in ichthyoses
Abstract During the past 20 years, tremendous progress has been made in our understanding of the molecular basis of many genetic skin conditions. The translation of these laboratory findings into effective therapies for affected individuals has been slow, however, in large part due to the risk of carcinogenesis from random viral genomic integration and the lack of efficacy of topically applied genetic material and most proteins. As intervention at the gene level still appears remote for most genetic disorders, increased knowledge about the cellular and biochemical pathogenesis of disease allows specific targeting of pathwa...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: Joey E. Lai‐Cheong, Peter M. Elias, Amy S. Paller Tags: Invited Article Source Type: research

Complications of ichthyosis beyond the skin
Abstract Although ichthyoses are noted for their skin features, like many dermatologic conditions, patients are often impacted in ways beyond the skin. Much has been described in recent years regarding quality of life and skin disorders. This is certainly the case for ichthyosis. For neonates or others with diffuse involvement of their skin, nutritional needs are often exceeding normal requirements. These can often result in growth abnormalities. Lastly, with specific subtypes of ichthyosis, compromise of tissues around the eyes and ears can be of concern to some patients. Certainly, some forms of ichthyosis are routinely ...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: Lucia Z. Diaz, John C. Browning, Aimee C. Smidt, William B. Rizzo, Moise L. Levy Tags: Invited Article Source Type: research

Systemic retinoids in the management of ichthyoses and related skin types
Abstract The term retinoid includes both natural and synthetic derivatives of vitamin A. Retinoid‐containing treatments have been used since ∼1550BC by the early Egyptians. Treatment of ichthyosiform disorders with retinoids dates back at least to the 1930s. Early use of high‐dose vitamin A demonstrated efficacy, but because vitamin A is stored in the liver, toxicity limited usefulness. Interest turned to synthetic retinoids in an effort to enhance efficacy and limit toxicity. Acetretin, isotretinoin and, in the past etretinate, have provided the most effective therapy for ichthyosiform conditions. They have been use...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: John J. DiGiovanna, Theodora Mauro, Leonard M. Milstone, Matthias Schmuth, Jorge R Toro Tags: Invited Article Source Type: research

Topical treatment of ichthyoses
Abstract Management of ichthyoses is a complex and continuously dynamic process. Primary treatments of ichthyosis are by means of topical moisturizers and topical medications. Patients and families need to have reasonable and realistic expectations when it comes to topical therapy. Topical medications cannot cure the scaling, but can gradually reduce it and thus improve their condition. No one treatment regimen works for everyone, and the best topical therapy for each patient may be the result of months (or years) of painstaking effort on both the physician's and the patient's behalf. As patients get older and their activi...
Source: Dermatologic Therapy - February 5, 2013 Category: Dermatology Authors: Philip Fleckman, Brandon D. Newell, Maurice A. Steensel, Albert C. Yan Tags: Invited Article Source Type: research

Transplantation of cyclic stretched fibroblasts accelerates the wound-healing process in streptozotocin-induced diabetic mice.
In this study, we found that mechanical strain prevents apoptosis and increases the adhesive ability of dermal fibroblasts in vitro, and thus confers the survival advantage in vivo after transplantation of fibroblasts into the full-thickness wound of diabetic mice. Cyclic stretch at a frequency of 0.5 Hz and maximum elongation of 20% stimulates cellular survival mediated by the activation of extracellular signal-regulated kinases (ERKs), c-Jun N-terminal kinases (JNKs), and the serine/threonine kinase Akt (AKT). Stretching of the fibroblasts increases the synthesis of extracellular matrix proteins and the formation of dens...
Source: Cell Transplantation - February 4, 2013 Category: Cytology Authors: Lee E, Kim DY, Chung E, Lee EA, Park KS, Son Y Tags: Cell Transplant Source Type: research

Cyanotoxins: Characteristics, production and degradation routes in drinking water treatment with reference to the situation in Serbia.
Abstract Cyanobacteria are members of phytoplankton of the surface freshwaters. The accelerated eutrophication of freshwaters, especially reservoirs for drinking water, by human activity has increased the occurrence and intensity of cyanobacterial blooms. They are of concern due to their ability to produce taste and odors compounds, a wide range of toxins, which have a hepatotoxic, neurotoxic, cytotoxic and dermatotoxic behavior, being dangerous to animal and human health. Therefore, the removal of cyanobacteria, without cell lysis, and releasing of intracellular metabolites, would significantly reduce the concentr...
Source: Chemosphere - February 4, 2013 Category: Chemistry Authors: Pantelić D, Svirčev Z, Simeunović J, Vidović M, Trajković I Tags: Chemosphere Source Type: research

Allergic Contact Dermatitis Caused by Methyl Aminolevulinate.
PMID: 23391490 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - February 4, 2013 Category: Dermatology Authors: Pastor-Nieto MA, Jiménez-Blázquez E, Sánchez-Herreros C, Belmar-Flores P Tags: Actas Dermosifiliogr Source Type: research

Erratum
Source: Australasian Journal of Dermatology - February 4, 2013 Category: Dermatology Tags: ERRATUM Source Type: research

Letter to the Editor
Source: Australasian Journal of Dermatology - February 4, 2013 Category: Dermatology Authors: Suran Fernando Tags: LETTER TO THE EDITOR Source Type: research

RE: The management of toxic epidermal necrolysis
Source: Australasian Journal of Dermatology - February 4, 2013 Category: Dermatology Authors: Chris Jalilian, Andrew Jevtic Tags: LETTER TO THE EDITOR Source Type: research

Chilblain lupus erythematosus in a patient affected by Hodgkin lymphoma
Source: Australasian Journal of Dermatology - February 4, 2013 Category: Dermatology Authors: Beatrice Passarini, Alessandro Pileri, Iria Neri, Bianca Maria Piraccini, Camilla Reggiani, Annalisa Patrizi Tags: LETTER TO THE EDITOR Source Type: research

In Other Journals
Source: Australasian Journal of Dermatology - February 4, 2013 Category: Dermatology Authors: Alan Watson Tags: IN OTHER JOURNALS Source Type: research

Porocarcinoma on the Face: A Rare Location. Review of the Literature to Explore Its Biological Behavior
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Brenda Guerrero‐Ramos, Judith Dominguez‐Pedroza, Lilly Esquivel‐Pedroza, Marcela Saeb‐Lima Tags: Communications and Brief Reports Source Type: research

Open Clinical Trial for Evaluation of Efficacy and Safety of a Portable “Dry‐Type” Iontophoretic Device in Treatment of Palmar Hyperhidrosis
ConclusionThe device is an effective therapeutic modality for palmar hyperhidrosis in addition to local injection of botulinum toxin, endoscopic sympathectomy, and conventional iontophoretic treatments.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Yoon Hyuk Choi, Seok‐Jong Lee, Do Won Kim, Weon Ju Lee, Gun Yoen Na Tags: Original Article Source Type: research

Multicenter, Randomized, Phase III Study of a Single Dose of IncobotulinumtoxinA, Free from Complexing Proteins, in the Treatment of Glabellar Frown Lines
ConclusionA single dose of 20 U of incobotulinumtoxinA demonstrated efficacy and safety in the treatment of glabellar frown lines using new Food and Drug Administration efficacy variables.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Alastair Carruthers, Jean Carruthers, William P. Coleman, Lisa Donofrio, Timothy Flynn, Michael Gold, Moritz Heinz, Laura Harrington, Derek Jones, David McDaniel, Thomas Rohrer, Andrea Schlöbe, Nowell Solish, Robert A. Weiss Tags: Original Article Source Type: research

Comparison of a Fractional Microplasma Radio Frequency Technology and Carbon Dioxide Fractional Laser for the Treatment of Atrophic Acne Scars: A Randomized Split‐Face Clinical Study
ConclusionBoth modalities have good effects on treating atrophic scars. PIH was not seen with the fractional microplasma RF, which might make it a better choice for patients with darker skin.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Zhen Zhang, Ye Fei, Xiangdong Chen, Wenli Lu, Jinan Chen Tags: Original Article Source Type: research

Combined Treatment of Earlobe Keloids with Shaving, Cryosurgery, and Intralesional Steroid Injection: A 1‐Year Follow‐Up
ConclusionThese results are highly encouraging because all patients showed improvement. Shaving associated with cryosurgery seems to be a useful treatment for large keloids scars.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Mariana Figueiroa Careta, Ana C. Fortes, Maria Cristina Messina, Celina W. Maruta Tags: Original Article Source Type: research

Modified Abscess Drainage in Treatment of Eight Cases with Hidradenitis Suppurativa in China
ConclusionModified abscess drainage is a simple and effective surgery for HS lesions, and patients tolerated this treatment well.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Xu Haoxiang, Li Chengrang, Wang Baoxi, Wu Xinfeng Tags: Original Article Source Type: research

Recurrence Rates of Aggressive Histologic Types of Basal Cell Carcinoma After Treatment with Electrodesiccation and Curettage Alone
ConclusionWe report a 27% recurrence rate for histologically aggressive BCCs treated using EDC alone with median 6.5 years follow‐up.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Elizabeth Blixt, David Nelsen, Erik Stratman Tags: Original Article Source Type: research

Prognosis of Patients with Transected Melanomas
ConclusionA high number of melanomas are transected at diagnosis, many of which lack visible tumor. The original Breslow's depth of transected melanomas without residual tumor on re‐excision accurately predicts survival and prognosis.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Kathryn J. Martires, Tina Nandi, Kord Honda, Kevin D. Cooper, Jeremy S. Bordeaux Tags: Original Article Source Type: research

Muscle Atrophy Beyond the Clinical Effect After a Single Dose of OnabotulinumtoxinA Injected in the Procerus Muscle: A Study with Magnetic Resonance Imaging
ConclusionThe gap between long‐term focal muscular atrophy and regained function remains to be elucidated. Future studies will be needed to investigate the complex interaction between focal neurogenic atrophy and potential compensatory functional muscle changes.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Inga K. Koerte, A. Sebastian Schroeder, Urban M. Fietzek, Ingo Borggraefe, Martina Kerscher, Steffen Berweck, Maximilian Reiser, Birgit Ertl‐Wagner, Florian Heinen Tags: Original Article Source Type: research

A Decade of Experience with Injectable Poly‐L‐Lactic Acid: A Focus on Safety
ConclusionImportant lessons have been learned that have enhanced the safety and efficacy of injectable PLLA and have made it a desirable product for restoring facial volume.
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Cynthia Bartus, C. William Hanke, Elizabeth Daro‐Kaftan Tags: Review Article Source Type: research

Vascular Skin Lesions in Children: A Review of Laser Surgical and Medical Treatments
Vascular anomalies are a common finding in children. Although most of these lesions are benign, they can be a severe cosmetic problem and cause structural and functional damage to nearby tissues. As a result, physicians are tasked with developing effective treatment options with superior safety profiles. Vascular anomalies may be divided into tumors and malformations. Vascular tumors, such as infantile hemangiomas, typically appear a few months after birth, whereas the majority of vascular malformations, such as port‐wine stains, are present at birth. Although these lesions vary in appearance, etiology, and disease cours...
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Lauren M. Craig, Tina S. Alster Tags: Review Article Source Type: research

Full‐Thickness Skin Grafts May Not Need Tie‐Over Bolster Dressings
Source: Dermatologic Surgery - February 4, 2013 Category: Dermatology Authors: Ikue Shimizu, Deborah F. MacFarlane Tags: Communications and Brief Reports Source Type: research

Kongresskalender 2013
Source: JDDG - February 4, 2013 Category: Dermatology Source Type: research