Dermatology News This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 18.

Pegfilgrastim‐induced Sweet's syndrome: a case report
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Mac Machan, Brian Matthys, Garth R. Fraga Tags: Case report Source Type: research

Treatment of a relapsing facial pyoderma gangrenosum (malignant pyoderma)
Abstract A case of rapidly relapsing pyoderma gangrenosum (PG) of the left preauricular area with no undermined borders is described. This might be considered a case of malignant pyoderma (PM), a rare variety of PG. Five months after complete healing obtained with systemic corticosteroids, the preauricular lesion of PG relapsed. As retreatment with oral methylprednisolone induced glucose intolerance and high arterial pressure, sulfa drugs were initially employed with a transitory recovery of the skin lesion. A successive prolonged course with minocycline induced a new complete resolution. To date, at six months' follow‐...
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Lucia Mantovani, Stefania Zauli, Oriele Sarno, Patrizia Querzoli, Monica Corazza, Annarosa Virgili Tags: Pharmacology and therapeutics Source Type: research

Efficacy of topical calcineurin inhibitors in vitiligo
Abstract Topical tacrolimus and pimecrolimus are indicated for the treatment of atopic dermatitis, but they have been studied in many off‐label uses. We reviewed the English language literature to define their roles in treatment of vitiligo. Double‐blind studies show that tacrolimus 0.1% ointment combined with excimer laser is superior to placebo, especially for UV resistant areas, such as bony prominences of the extremities. When used alone, tacrolimus 0.1% ointment is almost as effective as clobetasol propionate 0.05% ointment. Other studies suggest it can also be effective for facial lesions. Double blind studies sh...
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Russell Wong, Andrew N. Lin Tags: Pharmacology and therapeutics Source Type: research

Cutaneous scrotal metastasis: origins and clinical characteristics of visceral malignancies that metastasize to the scrotum
Abstract Cutaneous metastases occur in about 10% of patients with cancer, occasionally presenting as the initial sign of internal malignancy. Most often cutaneous metastases are an indicator of advanced cancer and are associated with a poor prognosis. The scrotum is a rare site of cutaneous metastasis, and metastatic tumor to the scrotum can be mistaken for other skin lesions. We reviewed the published literature regarding patients who developed cutaneous metastasis to the scrotum. We summarized the clinical characteristics of these men, including primary tumor sites, age at diagnosis, treatment regimens, interval between ...
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Brian S. Hoyt, Philip R. Cohen Tags: Review Source Type: research

Glucose transporter member 1 is involved in UVB‐induced epidermal hyperplasia by enhancing proliferation in epidermal keratinocytes
Conclusions We conclude that GLUT‐1 is involved in UVB‐induced epidermal hyperplasia by enhancing proliferation of epidermal basal cells, and the GLUT‐1‐related event might be regulated by an increase in HIF‐1α stimulated by EGF.
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Takumi Tochio, Hiroshi Tanaka, Satoru Nakata Tags: Report Source Type: research

Ustekinumab for the treatment of nail psoriasis in heavily treated psoriatic patients
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Magalys Vitiello, Antonella Tosti, Adriana Abuchar, Martin Zaiac, Francisco A. Kerdel Tags: Case report Source Type: research

Tuberculosis and cancer on a BCG vaccination site: an instance of immunocompromised district
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Ada Lo Schiavo, Marcella Brasiello, Sonia Sangiuliano, Eleonora Ruocco Tags: Correspondence Source Type: research

A case of infantile digital fibromatosis: differential diagnosis and treatment
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Bin Liu, Zhi‐cheng Xu, Ping‐qian Bao, Ting‐ze Hu, Yuan Li Tags: Correspondence Source Type: research

Is there an association between vitiligo and primary sclerosing cholangitis?
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Theodora Nakouti, Evangelos Cholongitas Source Type: research

Secondary syphilis on a psoriatic patient under cyclosporine: a challenging case
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Teresa Pinto‐Almeida, A. Rosmaninho, M. Sanches, R. Alves, M. Selores Tags: Correspondence Source Type: research

Ocular findings in patients with psoriasis
Conclusions Although results of our study support the necessity of routine ophthalmological examination of psoriasis patients for early diagnosis and treatment, we believe that further studies are required on the etiopathogenesis of ocular involvement in psoriasis patients.
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Berna Kilic, Umit Dogan, Ali Haydar Parlak, Nadir Goksugur, Mualla Polat, Didem Serin, Sedat Ozmen Tags: Report Source Type: research

Histiocytoid Sweet syndrome
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Serap Gunes Bilgili, Ayse Serap Karadag, Omer Calka, Gulay Bulut Tags: Correspondence Source Type: research

Kaposi’s sarcoma beneath a cutaneous horn
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Ümran Yavuzekinci, Deren Özcan, Ayşe Tülin Güleç Tags: Correspondence Source Type: research

Dots/globules on dermoscopy in nail‐apparatus melanoma
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Yuji Inoue, Scott W. Menzies, Satoshi Fukushima, Hazuki Nishi‐Kogushi, Azusa Miyashita, Shinichi Masukuchi, Faith Muchemwa, Toshiro Kageshita, Hironobu Ihn Tags: Case report Source Type: research

Five‐year history of pruritic plaques
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: John C. Chapman, Andrea Murina, Erin Boh Tags: Correspondence Source Type: research

Superficial angiomyxoma of the vulva complicated with condyloma acuminatum and Staphylococcus hominis infection
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Liancheng Zhu, Wei Zhao, Yu Shi, Bei Lin Tags: Case report Source Type: research

Targetoid lesions and neutrophilic dermatosis: an initial clinical and histological presentation of neonatal lupus erythematosus
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Sang Hee Lee, Mi Ryung Roh Tags: Case report Source Type: research

Lichen planus pemphigoides: four new cases and a review of the literature
We report four cases of LPP (three women aged respectively 47, 51, and 53 years old, and a 53‐year‐old man). All patients presented with bullae on lichenoid and normal skin, predominately on the extremities. The diagnosis was confirmed by immunohistological findings. Our patients were treated with oral corticosteroids with a good response. Our review of the literature of 78 cases of LPP (65 adults and 13 children) showed that it involved adults (mean age: 54 years), with a slight female preponderance. A mean lag time between LP and the development of LPP was 8.3 months. LPP is characterized by developing blisters...
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Ines Zaraa, Anis Mahfoudh, Myriam Kallel Sellami, Ines Chelly, Dalenda El Euch, Mohamed Zitouna, Mourad Mokni, Sondes Makni, Amel Ben Osman Tags: Review Source Type: research

Dermatophytoma: a clinicopathologic entity important for dermatologists and dermatopathologists to identify
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Daniel Bennett, Adam I. Rubin Tags: Correspondence Source Type: research

Fructose‐1,6‐bisphosphate aldolase A levels decrease in hair keratinocytes during androgenetic alopecia
Source: International Journal of Dermatology - January 20, 2013 Category: Dermatology Authors: Takumi Tochio, Hiroshi Tanaka, Satoru Nakata Tags: Correspondence Source Type: research

Clinical Snippets
Source: Experimental Dermatology - January 20, 2013 Category: Dermatology Tags: Clinical Snippets Source Type: research

Effect of human skin explants on the neurite growth of the PC12 cell line
Abstract The skin is a densely innervated organ. After a traumatic injury, such as an amputation, burn, or skin graft, nerve growth and the recovery of sensitivity take a long time and are often incomplete. The roles played by growth factors and the process of neuronal growth are crucial. We developed an in vitro model of human skin explants co‐cultured with a rat pheochromocytoma cell line differentiated in neuron in presence of nerve growth factor (NGF). This model allowed the study of the influence of skin explants on nerve cells and nerve fibre growth, probably through mediators produced by the explant, in a simplifi...
Source: Experimental Dermatology - January 20, 2013 Category: Dermatology Authors: Nicolas Lebonvallet, Jean‐Pierre Pennec, Christelle Gall, Ulysse Pereira, Nicholas Boulais, Jeremy Cheret, Christine Jeanmaire, Louis Danoux, Gilles Pauly, Laurent Misery Tags: Letter to the Editors Source Type: research

Inhibition of UV‐induced uric acid production using Allopurinol prevents suppression of the contact hypersensitivity response
Abstract Exposure to solar ultraviolet (UV) radiation suppresses adaptive immune responses. This contributes to skin carcinogenesis, but may protect from some autoimmune diseases. However, the molecular changes occurring within UV exposed skin that precipitate the downstream events leading to immune suppression are not fully understood. Using a combination of in vitro and in vivo mouse models we have discovered that UV induces significant cutaneous production of immune suppressive uric acid. The ability of UV‐induced uric acid to inhibit a contact hypersensitivity response was successfully blocked by the gout‐treating ...
Source: Experimental Dermatology - January 20, 2013 Category: Dermatology Authors: Sarah Leighton, Lai‐Fong Kok, Gary M. Halliday, Scott N. Byrne Tags: Regular Article Source Type: research

Hemizygous mutations in SNAP29 unmask autosomal recessive conditions and contribute to atypical findings in patients with 22q11.2DS
Background 22q11.2 deletion syndrome (22q11.2DS) is the most common microdeletion disorder, affecting an estimated 1 : 2000–4000 live births. Patients with 22q11.2DS have a broad spectrum of phenotypic abnormalities which generally includes congenital cardiac abnormalities, palatal anomalies, and immunodeficiency. Additional findings, such as skeletal anomalies and autoimmune disorders, can confer significant morbidity in a subset of patients. 22q11.2DS is a contiguous gene DS and over 40 genes are deleted in patients; thus deletion of several genes within this region contributes to the clinical features. Mutations o...
Source: Journal of Medical Genetics - January 20, 2013 Category: Genetics & Stem Cells Authors: McDonald-McGinn, D. M., Fahiminiya, S., Revil, T., Nowakowska, B. A., Suhl, J., Bailey, A., Mlynarski, E., Lynch, D. R., Yan, A. C., Bilaniuk, L. T., Sullivan, K. E., Warren, S. T., Emanuel, B. S., Vermeesch, J. R., Zackai, E. H., Jerome-Majewska, L. A. Tags: Open access, Editor's choice, Genetic screening / counselling, Molecular genetics, Dermatology, Epidemiology Genotype-phenotype correlations Source Type: research

Interexaminer reliability of infrared thermography for the diagnosis of complex regional pain syndrome
ConclusionsThe reliability of IRT for assessing skin temperature abnormalities in CRPS was high when the ROIs were determined based on patient history and symptoms.
Source: Skin Research and Technology - January 20, 2013 Category: Dermatology Authors: Eunjoo Choi, Pyung‐Bok Lee, Francis Sahngun Nahm Tags: Original Article Source Type: research

Can light‐field photography ease focusing on the scalp and oral cavity?
ConclusionLight‐field digital cameras are fast and easy to use. They can capture more information on the full depth of field compared with conventional cameras. However, the resolution of the pictures is relatively low.
Source: Skin Research and Technology - January 20, 2013 Category: Dermatology Authors: Arash Taheri, Steven R. Feldman Tags: Original Article Source Type: research

Seasonal and annual variation in the intensity of facial wrinkles
ConclusionThere was a gender‐dependent difference in the annual variation of wrinkle depth in subjects around 40 years of age. Seasonal environmental changes may affect on the eye wrinkles depth in men within a year.
Source: Skin Research and Technology - January 20, 2013 Category: Dermatology Authors: Kazue Tsukahara, Osamu Osanai, Takashi Kitahara, Yoshinori Takema Tags: Original Article Source Type: research

Automatic measurement of skin textures of the dorsal hand in evaluating skin aging
ConclusionThe method introduced in present study can be used to measure some skin aging parameters automatically and objectively. And it will save much time, reduce labor, and avoid measurement errors of deferent investigators when evaluating a great deal of skin images in a short time.
Source: Skin Research and Technology - January 20, 2013 Category: Dermatology Authors: Qian Gao, Jiaming Yu, Fang Wang, Tiantian Ge, Liwen Hu, Yang Liu Tags: Original Article Source Type: research

Development of skin aging scale by using dermoscopy
ConclusionDPAS is a reliable and valid diagnostic tool that can evaluate photoaged skin quantitatively by the help of objective criteria so can be used to evaluate the effect of preventive and therapeutic applications for skin aging.
Source: Skin Research and Technology - January 20, 2013 Category: Dermatology Authors: Burcu Isik, Mehmet S. Gurel, Asli T. Erdemir, Ozgu Kesmezacar Tags: Original Article Source Type: research

Positive nickel patch tests in infants are of low clinical relevance and rarely reproducible
ConclusionsOnly 9.5% of the children had reproducible nickel sulphate reactivity, while 62% became negative. The results are noteworthy and can be interpreted in different ways: Repeated nickel patch tests did not cause patch test sensitization. The test reactions in infancy are probably of irritant or non‐specific nature. Hence, nickel patch tests should only be performed in small children if there is a clinical suspicion of nickel‐induced allergic contact dermatitis.
Source: Pediatric Allergy and Immunology - January 20, 2013 Category: Allergy & Immunology Authors: Charlotte G. Mortz, Henrik F. Kjaer, Esben Eller, Morten Osterballe, Lene A. Norberg, Arne Høst, Carsten Bindslev‐Jensen, Klaus E. Andersen Tags: Original Article Source Type: research

Bronchial allergen challenges in children – safety and predictors
ConclusionsThe value of using the specific IgE and MCT as predictors was confirmed in a large number of patients. We also showed, for the first time, that the eNO predicted the EAR. The logistic regression model is repeatable with a good accuracy.
Source: Pediatric Allergy and Immunology - January 20, 2013 Category: Allergy & Immunology Authors: Johannes Schulze, Wanda Reinmüller, Eva Herrmann, Martin Rosewich, Markus A. Rose, Stefan Zielen Tags: Original Article Source Type: research

Molecular Dermatology
Methods and Protocolsseries:Methods in Molecular BiologyThe sustained skin research efforts over the past decades has led to the accumulation of a significant collection of information on skin structure and physiology as well as on the pathogenesis of cutaneous diseases. In Molecular Dermatology: Methods and Protocols, leading experts in the field provide a collection of state-of-the-art reliable protocols covering a wide spectrum of techniques ...
Source: Springer Biomedical Sciences titles - January 19, 2013 Category: Biomedical Science Tags: Molecular Medicine Source Type: news

Dynamic tensile properties of human skin - Gallagher AJ, Ni Anniadh A, Bruyere-Garnier K, Ottenio M, Xie H, Gilchrist MD.
The mechanical properties of skin are important for a number of applications including surgery, dermatology, impact biomechanics and forensic science. Studies have shown that the anisotropic effects of skin have been linked to sample orientation with respe...
Source: SafetyLit: All (Unduplicated) - January 19, 2013 Category: Global & Universal Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

Systems biology approaches to evaluate arsenic toxicity and carcinogenicity: An overview.
Abstract Long term exposure to arsenic, either through groundwater, food stuff or occupational sources, results in a plethora of dermatological and non-dermatological health effects including multi-organ cancer and early mortality. Several epidemiological studies, across the globe have reported arsenic-induced health effects and cancerous outcomes; but the prevalence of such diseases varies depending on environmental factors (geographical location, exposure level), and genetic makeup (and variants thereof); which is further modulated by several other factors like ethnicity, age-sex, smoking status, diet, etc. It is...
Source: International Journal of Hygiene and Environmental health - January 19, 2013 Category: Environmental Health Authors: Bhattacharjee P, Chatterjee D, Singh KK, Giri AK Tags: Int J Hyg Environ Health Source Type: research

Idiopathic Facial Aseptic Granuloma.
PMID: 23339993 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - January 19, 2013 Category: Dermatology Authors: Hiraldo-Gamero A, Vera-Casaño A, Sanz-Trélles A Tags: Actas Dermosifiliogr Source Type: research

Papular Mycosis Fungoides on the Legs: A Case Report.
PMID: 23339994 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - January 19, 2013 Category: Dermatology Authors: Santamarina-Albertos A, Muñoz-Martínez R, Alvarez-Gago T, Miranda-Romero A Tags: Actas Dermosifiliogr Source Type: research

Aggravation of Atopic Dermatitis‐Like Symptoms by Consecutive Low Concentration of Formaldehyde Exposure in NC/Nga Mice
In conclusion, we suggest that increased skin mRNA expressions of IL‐13, IL‐25/IL‐17E and COX‐2 by independent low concentration of FA exposure might be a key factor to exacerbate HDM‐mediated AD‐like skin inflammation.
Source: Experimental Dermatology - January 19, 2013 Category: Dermatology Authors: Ji‐Yun Kim, Mi Sook Jeong, Kui Young Park, Seong Jun Seo Tags: Letter to the Editors Source Type: research

Cutaneous lymphocyte associated antigen (CLA) as a novel predictive marker of TNF‐alpha inhibitor biological therapy in psoriasis
Abstract A considerable number of psoriatic patients shows secondary resistance during long‐term TNF‐alpha inhibitor therapy, necessitating the identification of reliable predictive markers. Predictive role of cutaneous lymphocyte associated antigen (CLA) was investigated. 38 severe psoriatic patients were treated for a 24‐week‐long study period. Clinical responsiveness (PASI) and changes of flow cytometry‐measured peripheral lymphocyte CLA expression (week 0‐2‐6) were statistically analysed. Regarding 24‐week‐long treatment outcome patients were divided into two groups: During the first 6 weeks mean CLA ...
Source: Experimental Dermatology - January 19, 2013 Category: Dermatology Authors: Hajnalka Jókai, József Szakonyi, Orsolya Kontár, Gábor Barna, Dóra Inotai, Sarolta Kárpáti, Péter Holló Tags: Letter to the Editors Source Type: research

P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis
Abstract Irritant contact dermatitis (ICD) is an inflammatory reaction caused by chemical toxicity on the skin. The P2X7 receptor (P2X7R) is a key mediator of cytokine release, which recruits immune cells to sites of inflammation. We investigated the role of P2X7R in croton oil (CrO)‐induced ICD using in vitro and in vivo approaches. ICD was induced in vivo by CrO application on the mouse ear and in vitro by incubation of murine macrophages and dendritic cells (DCs) with CrO and ATP. Infiltrating cells were identified by flow cytometry, histology and myeloperoxidase (MPO) determination. Effects of the ATP scavenger apyra...
Source: Experimental Dermatology - January 19, 2013 Category: Dermatology Authors: G. L. da Silva, N. D. M. Sperotto, T. J. Borges, C. Bonorino, C. M. Takyia, R. Coutinho‐Silva, M. M. Campos, R. F. Zanin, F. B. Morrone Tags: Regular Article Source Type: research

A lentiviral vector‐based genetic sensor system for comparative analysis of permeability and activity of vitamin D3 analogues in xenotransplanted human skin
In this study, we wish to establish an in vivo model that allows the comparison of permeability and activity of vitamin D3 analogues in human skin. We generate a bipartite, genetic sensor technology that combines efficient lentivirus‐directed gene delivery to xenotransplanted human skin with vitamin D3‐induced expression of a luciferase reporter gene and live imaging of animals by bioluminescence imaging. Based on the induction of a transcriptional activator consisting of the vitamin D receptor fused to the Gal4 DNA‐binding domain, the vitamin D3‐responsive sensor facilitates noninvasive and rapid assessment of per...
Source: Experimental Dermatology - January 19, 2013 Category: Dermatology Authors: Nicklas Heine Staunstrup, Rasmus O. Bak, Yujia Cai, Lars Svensson, Thomas K. Petersen, Cecilia Rosada, Karin Stenderup, Lars Bolund, Jacob Giehm Mikkelsen Tags: Regular Article Source Type: research

International guidelines for the in vivo assessment of skin properties in non‐clinical settings: Part 2. transepidermal water loss and skin hydration
ConclusionIt is anticipated that these guidelines will promote consistent data reporting, which will facilitate inter‐comparison of study results.
Source: Skin Research and Technology - January 19, 2013 Category: Dermatology Authors: Johan du Plessis, Aleksandr Stefaniak, Fritz Eloff, Swen John, Tove Agner, Tzu‐Chieh Chou, Rosemary Nixon, Markus Steiner, Anja Franken, Irena Kudla, Linn Holness Tags: Original Article Source Type: research

3T‐MRI analysis of epidermis and dermis moisturizing using the T2‐mapping sequence
Source: Skin Research and Technology - January 19, 2013 Category: Dermatology Authors: Calzolari Laura, Kastler Adrian, Mac‐Mary Sophie, Humbert Philippe, Kastler Bruno, Aubry Sebastien Tags: Letter to the Editor Source Type: research

Comparing the rates of absorption and weight loss during a desorption test using near infrared spectroscopy
Abstract The importance of determining skin hydration has over the years prompt the development of many instruments and methods, specifically designed to assess this parameter or water contents especially in the stratum corneum, and have greatly matured to suit different anatomical sites and measure multiple attributes. Of those, Near Infrared Spectroscopy (NIRS) has gained wide interest as a precise, safe, fast and noninvasive technique for determining skin hydration due to its high sensitivity to hydrogen bonding and ability to measure the amount of water in skin directly using the intensities of overtone and combination...
Source: Skin Research and Technology - January 19, 2013 Category: Dermatology Authors: M. Qassem, P. A. Kyriacou Tags: Original Article Source Type: research

Smartphone melanoma apps cause for concern
Smartphone applications that claim to be able to diagnose melanoma should be treated with extreme caution, say researchers.
Source: MedWire News - Dermatology - January 18, 2013 Category: Dermatology Source Type: news

Two Percent Of People Have Armpits That Never Smell
Two percent of people carry an unusual form of a specific gene (ABCC11) that means their armpits never smell. The finding came from new research involving 6,495 women who are enrolled in the Children of the 90s study at the University of Bristol, England, and was published in the Journal of Investigative Dermatology. In the study, 117 (2%) of the subjects were lucky enough to carry this gene that allows them to never have to worry about using deodorant...
Source: Health News from Medical News Today - January 18, 2013 Category: Consumer Health News Tags: Genetics Source Type: news

One million Brits can 'dump their deodorants'
Conclusion This is intriguing research following up on the previous finding that a particular DNA sequence variation in the ABCC11 gene is associated with both earwax and armpit sweat odour. One form of the variant is linked with dry earwax and less odorous sweat, while another is linked with wet earwax and more odorous sweat. The researchers did find that there was a link between which variant mothers had and their deodorant usage. However, almost 80% of women with the dry earwax, “non-odorous” variant still reported using deodorant around once a week. The researchers’ results indicate the same may be true for men,...
Source: NHS News Feed - January 18, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Genetics/stem cells Source Type: news

Top Of The List Of Reasons People Visit Doctors Are Skin Problems, Joint Disorders
A new Mayo Clinic Proceedings study shows that people most often visit their health care providers because of skin issues, joint disorders and back pain. Findings may help researchers focus efforts to determine better ways to prevent and treat these conditions in large groups of people. "Much research already has focused on chronic conditions, which account for the majority of health care utilization and costs in middle-aged and older adults," says Jennifer St. Sauver, Ph.D...
Source: Health News from Medical News Today - January 18, 2013 Category: Consumer Health News Tags: Dermatology Source Type: news

Tanning Bed Cancer Risk Double That Of Summer Sun
The risk of skin cancer from tanning beds is two times higher than spending the same length of time in the Mediterranean midday summer sun. The finding came from a new study conducted by a team of researchers at the University of Dundee, Scotland, and published in the British Journal of Dermatology. The scientists examined 400 tanning beds in the UK and measured their levels of ultraviolet (UV) radiation. UV radiation was emitted at levels above British and EU guidelines in nine out of ten beds...
Source: Health News from Medical News Today - January 18, 2013 Category: Consumer Health News Tags: Melanoma / Skin Cancer Source Type: news

Trichodysplasia spinulosa: A benign adnexal proliferation with follicular differentiation associated with polyomavirus.
Abstract Trichodysplasia spinulosa is a rare polyomavirus-associated cutaneous eruption occurring in the setting of immunosuppression. Clinically it is characterised by multiple centrofacial folliculocentric papules with spinous protuberances. The histopathology is distinct and treatment with antiviral agents appears to be the most effective. PMID: 23330716 [PubMed - as supplied by publisher]
Source: The Australasian Journal of Dermatology - January 18, 2013 Category: Dermatology Authors: Lee YY, Tucker SC, Prow NA, Setoh YX, Banney LA Tags: Australas J Dermatol Source Type: research

Recent advances in cutaneous melanoma: towards a molecular model and targeted treatment.
This article reviews the mechanisms of melanoma oncogenesis and classic molecular signalling pathways, targeted treatment approaches based on the molecular model and immunotherapy, and the advent of next-generation sequencing technologies in understanding the complexity of the melanoma pathogenome. In addition to the known somatic activating mutations BRAF and NRAS, exome sequencing has recently identified RAC1, a novel UV-signature gain-of-function mutation. Germline mutations associated with familial melanoma have added a further dimension to the molecular underpinnings of melanoma, implicating BAP1 and MITF as melanoma ...
Source: The Australasian Journal of Dermatology - January 18, 2013 Category: Dermatology Authors: Read J Tags: Australas J Dermatol Source Type: research