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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 17.

Demethylation of promoter regulatory elements contributes to CD70 overexpression in CD4+ T cells from patients with subacute cutaneous lupus erythematosusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Demethylation of regulatory elements contributes to CD70 overexpression in CD4+ T cells of patients with SCLE.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: Y. Luo, M. Zhao, Q. Lu Source Type: journals

Topical tazarotene vs. coal tar in stable plaque psoriasisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Tazarotene 0.1% gel has comparable clinical efficacy to CCT 5% ointment. CCT ointment remains a cost-effective therapy for plaque psoriasis.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: U. Kumar, I. Kaur, S. Dogra, D. De, B. Kumar Source Type: journals

Prevalence of acquired melanocytic naevi in Brazilian schoolchildrenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. In genetically predisposed people, the body-site distribution of AMN in a heterogeneous population (mixed ethnic backgrounds) is similar to that in a homogeneous population and has the same tendency toward potential proliferation of melanocytes in the presence of ultraviolet radiation. Strategies to reduce the incidence of MM should start at an early age. We believe that these findings will have a direct effect on concepts for preventive strategies. Studies in different populations may serve as a starting point for research into the mechanism underlying increasing rates of AMN.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: S. Yarak, M. M. Ogawa, S. Hirata, F. A. de Almeida Source Type: journals

Supraciliary wrinkles and botulinum toxin Aemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Injection of botulinum toxin type A through the temporal hairline to correct supraciliary wrinkles seems to be safe and effective.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: F. Ghalamkarpour, R. M. Robati, F. Aryanejad, P. Toossi Source Type: journals

c-Ski promotes skin fibroblast proliferation but decreases type I collagen: implications for wound healing and scar formationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Because of the important role of fibroblast proliferation and collagen secretion in tissue repair and scar formation, we speculate that c-Ski may be a new candidate molecule for accelerating wound healing and decreasing scar formation.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: X. Liu, P. Li, X.-Y. Chen, Y.-G. Zhou Source Type: journals

A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentiginesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Undecylenoyl phenylalanine 2% is a novel depigmenting agent, which possibly acts as an [alpha]-melanocyte-stimulating hormone antagonist, thus inhibiting melaninogenesis. It achieved a significant lightening of the lesions with minimal side-effects. Most patients were satisfied with the improvement. Undecylenoyl phenylalanine 2% may represent a safe, effective and inexpensive therapeutic alternative for solar lentigines.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: A. C. Katoulis, A. Alevizou, E. Bozi, M. Makris, A. Zafeiraki, N. Mantas, F. Kousta, M. Mistidou, A. Kanelleas, N. G. Stavrianeas Source Type: journals

Are dark-skinned people really protected from ultraviolet radiation?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Dark-skinned people are not completely protected from the effects of UVR.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: A. L. Young, S. Levy, M. Nighland, R. Grossman, D. N. Silvers, J. T. Celebi Source Type: journals

Effects of hyaluronan and iodine on wound contraction and granulation tissue formation in rat skin woundsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Hyiodine supports wound healing by stimulating wound contraction and epidermal proliferation and by keeping the wound moist through increased exudation.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: R. Slavkovsky, R. Kohlerova, A. Jiroutova, M. Hajzlerova, L. Sobotka, E. Cermakova, J. Kanta Source Type: journals

Pemphigus herpetiformis: analysis of the autoantibody profile during the disease course with changes in the clinical phenotypeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Our patient presented features characteristic of PH. Although circulating anti-Dsg3 antibodies were present, the patient had only cutaneous involvement for a long period. Our findings indicate that the proposed Dsg compensation theory cannot always explain the clinical phenotype, changes in which may occur without apparent modification of the autoantibody profile and antibody specificity. Hence, additional factors, such as Fc[gamma]-dependent neutrophil activation, may critically affect the clinical presentation of pemphigus.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: S. Lebeau, R. Müller, I. Masouyé, M. Hertl, L. Borradori Source Type: journals

Serum T helper 1 cytokine levels are greater in patients with alopecia areata regardless of severity or atopyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Increased Th1 serum cytokines (IL-2, IL-12 and interferon-[gamma]) and IL-1ra levels are associated with AA regardless of disease severity or the presence of atopy.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: N. Barahmani, A. Lopez, D. Babu, M. Hernandez, S. E. Donely, M. Duvic Source Type: journals

Coudability hairs: a revisited sign of alopecia areata assessed by trichoscopyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Coudability hairs, more closely perceived by trichoscopy, are useful-markers for disease activity in AA and provide a surrogate-marker for the hair-pull test.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: S. Inui, T. Nakajima, S. Itami Source Type: journals

Association of HLA-DRB1* and keloid disease in an Afro-Caribbean populationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. This study does not support an association between HLA-DRB1* alleles and susceptibility to keloid in people of Afro-Caribbean origin.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: J. J. Brown, W. E. R. Ollier, G. Arscott, A. Bayat Source Type: journals

Randomized controlled trial comparing store-and-forward teledermatology alone and in combination with web-camera videoconferencingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Intraobserver reliability is very high in teledermatology. When history taking and training in digital photography are standardised, a hybrid system with audio is no better than SF alone.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: G. Romero, P. Sánchez, M. García, P. Cortina, E. Vera, J. A. Garrido Source Type: journals

Psychiatric treatments in dermatology: an updateemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article summarises common psychiatric conditions seen in patients with skin disease, both primary psychiatric disorders and psychiatric disorders secondary to dermatological pathology. Diagnosis of relevant psychiatric conditions such as anxiety, depression, obsessive[ndash]compulsive disorder, delusional parasitosis and dermatitis artefacta, and psychiatric treatments are discussed. It gives an update of psychopharmacology relevant to the dermatologist including important interactions between psychotropic and dermatological agents.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: R. Sambhi, P. Lepping Source Type: journals

Aggressive digital papillary adenocarcinoma: a reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vigorous treatment of aggressive digital papillary adenocarcinoma (ADPA), including amputation, has been recommended by most authors, but the appropriateness and effectiveness of excision as an alternative to amputation has not been systematically evaluated. To evaluate the appropriateness and effectiveness of excision as an alternative to amputation in the treatment of ADPA, we reviewed the clinical presentations, treatments and patient outcomes presented in case reports on ADPA available on Ovid MEDLINE. We also assessed the results of immunohistochemical staining for proliferation markers in one patient in order to expl...
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: H.-C. Hsu, C.-Y. Ho, C.-H. Chen, C.-H. Yang, H.-S. Hong, Y.-H. Chuang Source Type: journals

Perinatal exposure to endotoxin and the development of eczema during the first 6 years of lifeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. Endotoxin exposure during infancy is unlikely to have a large long-term effect on the development of eczema, especially the atopic form.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: C.-M. Chen, S. Sausenthaler, W. Bischof, O. Herbarth, M. Borte, H. Behrendt, U. Krämer, H. C. Williams, H.-E. Wichmann, J. Heinrich Source Type: journals

Corticosteroid/cyclophosphamide pulse treatment in South African patients with pemphigusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Pulse treatment in our setting was associated with minimal morbidity. In the nine patients who relapsed, the regimen was not strictly followed, emphasizing the importance of compliance. Our use of low-dose oral corticosteroids between treatment pulses, early in the management of poorly controlled patients, supports the current modified recommendation of Pasricha.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: F. Shaik, J. Botha, J. Aboobaker, A. Mosam Source Type: journals

Advances in paracoccidioidomycosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America. It is becoming globally relevant, as increasing numbers of cases have been detected in returning travellers and immigrants from endemic regions. It is characterized by pulmonary involvement, lymphadenopathy, and chronic progression of mucocutaneous lesions. Untreated, systemic disease can be severe and fatal. Skin features are common and characteristic, enabling the dermatologist to diagnose infection early and prevent the development of serious sequelae. This review outlines the clinical features and management of paracoccidioidomycosis and di...
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: M. Ameen, C. Talhari, S. Talhari Source Type: journals

Effect of levothyroxine treatment on clinical symptoms and serum cytokine levels in euthyroid patients with chronic idiopathic urticaria and thyroid autoimmunityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. These results suggest that levothyroxine treatment is not a reasonable option in euthyroid patients with CIU and thyroid autoimmunity. Augmentation of cytokine production after levothyroxine treatment seems to be related to the immunomodulatory effects of TSH-suppressive treatment.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: S. Kiyici, O. O. Gul, E. B. Baskan, S. Hacioglu, F. Budak, E. Erturk, S. Imamoglu Source Type: journals

Predictors of patient satisfaction with initial diagnosis and management of malignant melanomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Patients whose initial biopsy was taken by dermatologist were more satisfied than those with a biopsy taken by a GP. The number of visits was an important predictor of patient satisfaction.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: N. Sheth, S. J. Sarker, M. Harries, C. Healy, R. Russell-Jones, K. Acland Source Type: journals

Axillary hair removal with 1064-nm Nd:YAG laser increases sweat productionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. The results of this study confirm that treatment of axillary hair using the 1064-nm Nd:YAG laser can cause hyperhidrosis, and this effect is not transient. We did not evaluate the eccrine glands histologically, which is a limitation of the study.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: F. Aydin, G. S. Pancar, N. Senturk, Y. Bek, E. P. Yuksel, T. Canturk, A. Y. Turanli Source Type: journals

Neurotropin inhibits both capsaicin-induced substance P release and nerve growth factor-induced neurite outgrowth in cultured rat dorsal root ganglion neuronesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. These results suggest that NTP exerts its antipruritic effects by inhibiting both SP release and neurite outgrowth of cutaneous sensory nerves.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: K. Taneda, M. Tominaga, S. Tengara, H. Ogawa, K. Takamori Source Type: journals

Genotoxic effects of 1064-nm Nd:YAG and 532-nm KTP lasers on fibroblast cell culturesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Different patterns of cellular damage were seen for different cell-culture passages, treatment doses, and laser wavelengths. These dose ranges are generally used for the treatment of vascular and pigmented lesions and for rejuvenation purposes. As replicative ageing or cell senescence is one of the critical factors determining the extent of cell damage induced by laser therapy, these results may have important implications for clinical practice.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: N. Senturk, A. Bedir, B. Bilgici, F. Aydin, A. Okuyucu, Z. C. Ozmen, A. Y. Turanli Source Type: journals

The profile of dermatological problems in primary careemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Dermatological disorders make up a significant proportion of general practitioners' workload. The diagnostic profile of primary-care dermatology differs markedly from that of hospital practice. General practitioners may benefit from training specifically tailored to the common primary-care dermatological conditions.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: O. A. Kerr, M. J. Tidman, J. J. Walker, R. D. Aldridge, E. C. Benton Source Type: journals

Mucosal (oral and vulval) lichen planus in women: are angiotensin-converting enzyme inhibitors protective, and beta-blockers and non-steroidal anti-inflammatory drugs associated with the condition?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Beta-blockers and NSAIDS are associated with LP, suggesting that withdrawal of these drugs should be considered. Further studies are needed to confirm or refute the inverse relationship between mucosal LP and use of ACE inhibitors.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: R. Clayton, S. Chaudhry, I. Ali, S. Cooper, T. Hodgson, F. Wojnarowska Source Type: journals

Clopidogrel: mechanisms of action and review of the evidence relating to use during skin surgery proceduresemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article examines the mechanism of action of clopidogrel, current practice, and evidence for or against continuing its use during skin surgery. The mechanisms of action of aspirin, warfarin, heparin and NSAIDS will also be briefly discussed.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: L. C. Stewart, J. A. A. Langtry Source Type: journals

Therapeutic options for palmoplantar pustulosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Palmoplantar pustulosis (PPP) is a common chronic and recurrent pustular dermatosis characterized by multiple sterile pustules and erythematous plaques on the palms and soles. The exact cause and pathogenesis of the disease remain unknown, and there is still debate about whether PPP is a variant of psoriasis or a distinct condition. A review of the medical literature revealed that a wide range of treatments have been used in the treatment of PPP over the years. The literature in PPP is restricted to case reports or small case series, and there is a lack of well-documented clinical studies, which makes it difficult to selec...
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: E. Adişen, M. A. Gürer Source Type: journals

A case–control analysis and laboratory study of the two feet–one hand syndrome in two dermatology hospitals in Chinaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. Contact between hands and feet probably results in the transmission of dermatophytes from the feet to the scratching hand.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: P. Zhan, Y. P. Ge, X. L. Lu, X. D. She, Z. H. Li, W. D. Liu Source Type: journals

Oxidative protein damage and antioxidant status in systemic lupus erythematosusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions. The findings suggest that protein oxidation may play a role in the pathogenesis of chronic organ damage in SLE.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: Q. Zhang, D. Q. Ye, G. P. Chen, Y. Zheng Source Type: journals

Comparison of two dye lasers in the treatment of port-wine stainsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. Both laser systems are equivalent in terms of efficacy and pain.
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: M. Frohm Nilsson, S. Passian, D. Wiegleb Edstrom Source Type: journals

Strahlenheilkundeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologica 1940;82:400-423 (DOI:10.1159/000253843)
Source: Dermatology - October 22, 2009 Category: Dermatology Source Type: journals

Lymphogranuloma inguinale, Ulcus molle, Bekämpfung der Geschlechtskrankheiten, Sexualwissenschaftemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologica 1940;82:369-400 (DOI:10.1159/000253842)
Source: Dermatology - October 22, 2009 Category: Dermatology Source Type: journals

Zur Frage der als Spätformen des Lymphogranulom-Erregers beschriebenen Gebildeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatologica 1940;82:364-368 (DOI:10.1159/000253841)
Source: Dermatology - October 22, 2009 Category: Dermatology Source Type: journals

Retrospective analysis of systemic treatments for psoriasis patients attending a Psocare center in Florence. Relevance of biological drugs use and comorbiditiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Current treatments have to consider general health conditions and patients habits. In this picture, biological drugs are emerging as the therapy of choice for their good efficacy in the long term management of psoriasis.
Source: Journal of the European Academy of Dermatology and Venereology - October 22, 2009 Category: Dermatology Authors: F Prignano, L Pescitelli, F Ricceri, T Lotti Source Type: journals

An Italian shared dermatological and rheumatological proposal for the use of biological agents in psoriatic diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion We provide a shared dermatological and rheumatological proposal for the use of biological agents in PD.
Source: Journal of the European Academy of Dermatology and Venereology - October 22, 2009 Category: Dermatology Authors: A Marchesoni, G Altomare, M Matucci-Cerinic, N Balato, I Olivieri, C Salvarani, T Lotti, R Scarpa, GA Vena, G Valesini, A Giannetti Source Type: journals

Analysis of four prevalent filaggrin mutations (R501X, 2282del4, R2447X and S3247X) in Austrian and German patients with atopic dermatitisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Our data confirm and extend the knowledge of the influence of FLG mutations in AD.
Source: Journal of the European Academy of Dermatology and Venereology - October 22, 2009 Category: Dermatology Authors: EK Greisenegger, N Novak, L Maintz, T Bieber, F Zimprich, D Haubenberger, A Gleiss, G Stingl, T Kopp, A Zimprich Source Type: journals

The risk of psoriatic arthritis remains constant following initial diagnosis of psoriasis among patients seen in European dermatology clinicsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions The incidence of PsA was constant after initial diagnosis of psoriasis, leading to a higher prevalence of concomitant PsA over time. PsA is associated with decreased QoL and increased work-related problems, HCRU and comorbidities. Dermatologists should screen for PsA in their patients, especially long-standing patients who did not initially present with PsA.
Source: Journal of the European Academy of Dermatology and Venereology - October 22, 2009 Category: Dermatology Authors: E Christophers, JNWN Barker, CEM Griffiths, E Daudén, G Milligan, C Molta, R Sato, R Boggs Source Type: journals

Capparis spinosa protects against oxidative stress in systemic sclerosis dermal fibroblastsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, ECS exhibits a notable activity in protecting against oxidative stress and interrupting of ROS-ERK1/2-Ha-Ras signal loop in SSc, suggesting its potential protective effects against skin sclerosis. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00403-009-0998-7Authors Yue-lan Cao, Zhejiang University Department of Dermatology, Second Affiliated Hospital, School of Medicine 88 Jiefang Road 310009 Hangzhou ChinaXin Li, Hangzhou Center for Disease Control and Prevention Department of STD and AIDS Prevention 310006 Hangzhou ChinaMin Zheng, Zhejiang University Department of Dermatology, Sec...
Source: Archives of Dermatological Research - October 22, 2009 Category: Dermatology Tags: Archives of Dermatological Research Source Type: journals

Basic measures and systemic medical treatment of patients with toxic epidermal necrolysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Immediate beginning of therapy is essential for a successful treatment of toxic epidermal necrolysis. Besides systemic therapy with corticosteroids, certain basic measures such as isolation of patients at adequate room temperature to prevent hypothermia, strict control of circulation, temperature and laboratory parameters, daily smears of skin and mucous membranes and a diet rich in calories due to the catabolic metabolic status are very important for successful outcome.
Source: JDDG - October 21, 2009 Category: Dermatology Authors: Imke Hanken, Melanie Schimmer, Christian A. Sander Source Type: journals

Acceleration of permeability barrier recovery by exposure of skin to 10–30 kHz soundemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions These results suggest that epidermal keratinocytes might be influenced by ultrasound in a manner that results in modulation of epidermal permeability barrier homeostasis.
Source: British Journal of Dermatology - October 21, 2009 Category: Dermatology Authors: M. Denda, M. Nakatani Source Type: journals

Upregulation of cathepsin S in psoriatic keratinocytesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Upregulation of cathepsin S in psoriatic keratinocytes. Experimental Dermatology 2009.Abstract: Cathepsin S (CATS) is a cysteine protease, well known for its role in MHC class II-mediated antigen presentation and extracellular matrix degradation. Disturbance of the expression or metabolism of this protease is a concomitant feature of several diseases. Given this importance we studied the localization and regulation of CATS expression in normal and pathological human/mouse skin. In normal human skin CATS-immunostaining is mainly present in the dermis and is localized in macrophages, Langerhans, T-...
Source: Experimental Dermatology - October 21, 2009 Category: Dermatology Authors: Alexander Schönefuß, Wiebke Wendt, Benjamin Schattling, Roxane Schulten, Klaus Hoffmann, Markus Stuecker, Christian Tigges, Hermann Lübbert, Christine Stichel Source Type: journals

Dysregulation of CD36 upon TLR-2 stimulation in monocytes from patients with atopic dermatitis and the TLR2 R753Q polymorphismemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The differences in CD36 expression in TLR-2 polymorph AD patients compared to wild type AD patients and healthy controls may be associated with an enhanced susceptibility to skin infections with S. aureus.
Source: Experimental Dermatology - October 21, 2009 Category: Dermatology Authors: Margarete Niebuhr, Jens Langnickel, Stefanie Sigel, Thomas Werfel Source Type: journals

Influence of narrowband UVB phototherapy on vitamin D and folate statusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Low-dose nUVB treatment gives a significant increase (P < 0.001) of the vitamin D status in persons with low initial levels of 25(OH)D, but no effect on the folate level.
Source: Experimental Dermatology - October 21, 2009 Category: Dermatology Authors: Emanuela Cicarma, Cato Mørk, Alina Carmen Porojnicu, Asta Juzeniene, Tran Thi Thu Tam, Arne Dahlback, Johan Moan Source Type: journals

Mouse models for melanoma: a personal perspectiveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Mouse models for melanoma: a personal perspective. Experimental Dermatology 2009.Abstract: Complex biological processes often require in vivo analysis, and many important research advances have been made using mice as a model for the study of various biological systems. Cutaneous melanomas are tumors originating from skin melanocytes, which are present in hair follicles, and interfollicular epidermal and dermal layers. Until recently, mouse melanoma models were largely based on transplantation models, i.e. transplantation of either syngeneic or xenogeneic melanoma cells into wild type or genetica...
Source: Experimental Dermatology - October 21, 2009 Category: Dermatology Authors: Jürgen C. Becker, Roland Houben, David Schrama, Heike Voigt, Selma Ugurel, Ralph A. Reisfeld Source Type: journals

Effect of topical application and intraperitoneal injection of oregonin on atopic dermatitis in NC/Nga miceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Please cite this paper as: Effect of topical application and intraperitoneal injection of oregonin on atopic dermatitis in NC/Nga mice. Experimental Dermatology 2009.Abstract: The diarylheptanoid, oregonin (ORE), which was isolated from the bark of Alnus japonica Steudel that grows natively in Korea, has been known to exert antioxidative, anti-inflammatory, anti-cancer and immune response inhibitory effects. The antioxidative effect of ORE was observed on the superoxide and 1,1-diphenyl-2-picrylhydrazyl radical, as well as on the expression of inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide-treat...
Source: Experimental Dermatology - October 21, 2009 Category: Dermatology Authors: Sun Eun Choi, Mi Sook Jeong, Myung Joo Kang, Do Ik Lee, Seong Soo Joo, Chung Soo Lee, Hyoweon Bang, Mi-Kyung Lee, Soon-Chul Myung, Young Wook Choi, Kap-sok Lee, Seong Jun Seo, Min Won Lee Source Type: journals

Successful treatment of cheilitis granulomatosa with intralesional injection of triamcinoloneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Journal of the European Academy of Dermatology and Venereology - October 21, 2009 Category: Dermatology Authors: C Bacci, ML Valente Source Type: journals

Topical Antibiotic Treatment for Uncomplicated Skin and Skin Structure Infections: Review of the Literatureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Are topical antibiotic treatment options for uncomplicated skin infections effective? Expert Review of Anti-Infective Therapy
Source: Medscape Dermatology Headlines - October 21, 2009 Category: Dermatology Tags: Infectious Diseases Source Type: info

Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase A, in systemic sclerosis: association with pulmonary fibrosis and vascular damageemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Systemic sclerosis (SSc) is a connective tissue disease characterized by fibrosis and vascular changes in the skin and internal organs with autoimmune background. It has been suggested that oxidative stress plays an important role in the development of SSc. To determine the prevalence and clinical correlation of autoantibody to methionine sulfoxide reductase A (MSRA), one of the antioxidant repair enzymes, in SSc, serum anti-MSRA autoantibody levels were examined in patients with SSc by enzyme-linked immunosorbent assay using recombinant MSRA. The presence of anti-MSRA antibody was evaluated by immu...
Source: Archives of Dermatological Research - October 21, 2009 Category: Dermatology Tags: Archives of Dermatological Research Source Type: journals

With Microdermabrasion, Rough Seems to Work Betteremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: With Microdermabrasion, Rough Seems to Work BetterCategory: Health NewsCreated: 10/21/2009 8:10:00 AMLast Editorial Review: 10/21/2009
Source: MedicineNet Skin General - October 21, 2009 Category: Dermatology Source Type: consumer

Over-the-counter scar products for postsurgical patients: Disparities between online advertised benefits and evidence regarding efficacyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Surgical patients frequently read about over-the-counter (OTC) scar products online and ask physicians for advice about product use. We summarized the characteristics of the 20 best-selling scar products on the Web site drugstore.com and reviewed the medical literature for data supporting the efficacy of OTC scar products used on fresh postsurgical wounds. Products had an average price of $16.25 (range $9.49-$59.99) and an average of 9.2 ingredients (range 1-29). Silicone, vitamin E, and onion extract were common ingredients. Although weak evidence indicates that silicone gel dressings may improve postsurgical scar appeara...
Source: Journal of the American Academy of Dermatology - October 21, 2009 Category: Dermatology Authors: Pamela Morganroth, Alissa Cowden Wilmot, Christopher Miller Tags: JAAD Online Source Type: journals