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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 25.

Stratum corneum integrity as a predictor for peristomal skin problems in ostomatesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Successive tape stripping, a situation analogous to the normal use of a pouching system, caused a higher degree of barrier damage more rapidly in patients with PSP, indicating an impaired mechanical quality of the barrier. The SLS exposure test suggested a generally increased susceptibility to irritant dermatitis as assessed by TEWL. Our findings suggest tape stripping and SLS testing may have a role as predictive tests to identify patients at risk of PSP.
Source: British Journal of Dermatology - October 7, 2009 Category: Dermatology Authors: H. Nybaek, S. Lophagen, T. Karlsmark, D. Bang Knudsen, G.B.E. Jemec Source Type: journals

Burn Rate in Kids Has Dropped, But Still Causes Concernemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Burn Rate in Kids Has Dropped, But Still Causes ConcernCategory: Health NewsCreated: 10/6/2009 12:10:00 PMLast Editorial Review: 10/7/2009
Source: MedicineNet Skin General - October 7, 2009 Category: Dermatology Source Type: consumer

The association between hand eczema and nickel allergy has weakened among young women in the general population following the Danish nickel regulation: results from two cross-sectional studiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Regulatory control of nickel exposure may have reduced the effect of nickel on hand eczema in the young female population.
Source: Contact Dermatitis - October 6, 2009 Category: Dermatology Authors: Jacob Pontoppidan Thyssen, Allan Linneberg, Torkil Menné, Niels Henrik Nielsen, Jeanne Duus Johansen Source Type: journals

Author Index / Subject Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:44 (DOI:10.1159/000247292)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Editor's Remarksemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:41-43 (DOI:10.1159/000247291)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Cyclosporin Therapy in Psoriasis: Recommendations for Treatmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:38-40 (DOI:10.1159/000247290)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Management of Erythrodermic Psoriasis with Low-Dose Cyclosporinemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:30-37 (DOI:10.1159/000247289)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Short- and Long-Term Considerations concerning the Management of Plaque Psoriasis with Low-Dose Cyclosporinemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:19-29 (DOI:10.1159/000247288)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Contents, Vol. 187, Supplement 1, 1993email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:I (DOI:10.1159/000247287)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Cyclosporin versus Etretinate: Italian Multicenter Comparative Trial in Severe Plaque-Form Psoriasisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:8-18 (DOI:10.1159/000247286)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Cyclosporin in Psoriasis: Pathophysiology and Experimental Dataemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:3-7 (DOI:10.1159/000247285)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Editor's Introductionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:1 (DOI:10.1159/000247284)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Subject Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:319-320 (DOI:10.1159/000247283)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Author Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:317-318 (DOI:10.1159/000247282)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Acknowledgment to Refereesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:315 (DOI:10.1159/000247281)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Erratumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:314 (DOI:10.1159/000247280)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Superficial Granulomatous Pyodermaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:312-314 (DOI:10.1159/000247279)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Keratosis extremitatum (Greither's Disease): Clinical Features, Histology, infrastructureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:309-311 (DOI:10.1159/000247278)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Bullous Systemic Lupus ergthematosusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:306-308 (DOI:10.1159/000247277)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

The Incidence of Sweet's Syndrome in Genevaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:303-305 (DOI:10.1159/000247276)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Chronic Cutaneous Infection Caused by Mycobacterium gordonaeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:301-302 (DOI:10.1159/000247275)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Mycobacterium chelonae Infection of Lymph Nodes in an HIV-lnfected Patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:299-300 (DOI:10.1159/000247274)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Pili trianguli et canaliculi: A Distinctive Hair Shaft Defect Leading to Uncombable Hairemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatology 1993;187:296-298 (DOI:10.1159/000247273)
Source: Dermatology - October 6, 2009 Category: Dermatology Source Type: journals

Vitiligoemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: VitiligoCategory: Diseases and ConditionsCreated: 7/11/1999 5:59:00 AMLast Editorial Review: 10/6/2009
Source: MedicineNet Skin General - October 6, 2009 Category: Dermatology Source Type: consumer

Health Tip: Reduce Your Risk of Skin Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Health Tip: Reduce Your Risk of Skin CancerCategory: Health NewsCreated: 10/6/2009 8:10:00 AMLast Editorial Review: 10/6/2009
Source: MedicineNet Skin General - October 6, 2009 Category: Dermatology Source Type: consumer

Human eyelash characterizationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions The eyelash is structurally very close to curly hair but some biological processes related to follicle cycle and pigmentation differ markedly.
Source: British Journal of Dermatology - October 5, 2009 Category: Dermatology Authors: S. Thibaut, E. De Becker, L. Caisey, D. Baras, S. Karatas, O. Jammayrac, P.J. Pisella, B.A. Bernard Source Type: journals

Erythema gyratum repens, not always a bad omen for patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Journal of the European Academy of Dermatology and Venereology - October 5, 2009 Category: Dermatology Authors: E Demonchy, J-P Lacour, J-P Ortonne, T Passeron Source Type: journals

Treatment of nail psoriasis with adalimumab: an open label unblinded studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Despite the lack of a control group, our results demonstrate a beneficial effect of adalimumab on psoriatic nail disease.
Source: Journal of the European Academy of Dermatology and Venereology - October 5, 2009 Category: Dermatology Authors: D Rigopoulos, S Gregoriou, E Lazaridou, E Belyayeva, Z Apalla, M Makris, A Katsambas, D Ioannides Source Type: journals

Quality of life and psychological adaptation of Korean adolescents with vitiligoemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion The quality of life of adolescents with vitiligo is closely related to the patients' apprehensions about their disease, psychosocial adjustment, and psychiatric morbidity, rather than the clinical severity of the condition itself. Clinicians should recognize and deal with psychological adaptation along with medical intervention when treating adolescent patients with vitiligo.
Source: Journal of the European Academy of Dermatology and Venereology - October 5, 2009 Category: Dermatology Authors: S Choi, D-Y Kim, S-H Whang, J-H Lee, S-K Hann, Y-J Shin Source Type: journals

Photoepilation with variable pulsed light in non-facial body areas: evaluation of efficacy and safetyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion The VPL[trade] System is a relatively efficient and safe treatment for long-term hair removal. Higher SPT (III and IV) with black and medium to coarse hair, and younger age of the patients appear to be factors of significant importance predicting long-term efficacy.
Source: Journal of the European Academy of Dermatology and Venereology - October 5, 2009 Category: Dermatology Authors: G Holzer, H Nahavandi, R Neumann, R Knobler Source Type: journals

Guidelines for practical use of MAL-PDT in non-melanoma skin canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Methyl aminolaevulinate photodynamic therapy is increasingly practiced in the treatment of actinic keratoses, Bowen's disease and basal cell carcinomas. This method is particularly suitable for treating multiple lesions, field cancerization and lesions in areas where a good cosmetic outcome is of importance. Good treatment routines will contribute to a favourable result. The Norwegian photodynamic therapy (PDT) group consists of medical specialists with long and extensive PDT experience. With support in the literature, this group presents guidelines for the practical use of topical PDT in non-melanoma skin cancer.
Source: Journal of the European Academy of Dermatology and Venereology - October 5, 2009 Category: Dermatology Authors: E Christensen, T Warloe, S Kroon, J Funk, P Helsing, AM Soler, HJ Stang, Ø Vatne, C Mørk Source Type: journals

The possible relevance of sex hormones on irritant and allergic responses: their importance for skin testingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dermatological responses are affected by the menstrual cycle phase in female patients, an unsurprising observation as oestrogen and progesterone affect the skin and immunological function, with oestrogen suppression of cellular immunity in particular. Exacerbation of dermatological symptoms is typically observed in either the latter phase of the menstrual cycle or during menstruation. The allergic response is diminished in the ovulatory phase and heightened in the progestinic phase. Definitive conclusions with regard to the effect of reproductive hormones on skin disorders have been somewhat hampered by a body of research ...
Source: Contact Dermatitis - October 5, 2009 Category: Dermatology Authors: Miranda A. Farage, Enzo Berardesca, Howard Maibach Source Type: journals

Reactions to resin-based dental materials in patients–type, time to onset, duration, and consequence of the reactionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Immediate reactions to resin-based materials were more prevalent than delayed allergic reactions, and the mechanism of the immediate reactions is probably non-allergic in most cases. There is a need for developing provocation tests to verify the association between the reaction and the material, and also to identify the offending component.
Source: Contact Dermatitis - October 5, 2009 Category: Dermatology Authors: Anders Tillberg, Berndt Stenberg, Anders Berglund Source Type: journals

Does allergic contact dermatitis from formaldehyde in clothes treated with durable-press chemical finishes exist in the USA?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objectives of this review are (i) to investigate whether clothes sold in the USA may contain enough free formaldehyde to elicit ACD in previously sensitized individuals and (ii) to assess the validity of US reports on ACD from formaldehyde in DPCF treated clothes. Literature was examined using various resources. The threshold level for formaldehyde in clothes that may cause ACD in sensitized individuals is unknown; we present data suggesting that levels < 200 ppm will be safe for most patients and that textiles will rarely contain higher amounts. All US studies presenting patients with ACD from formaldehyde in clothes ...
Source: Contact Dermatitis - October 5, 2009 Category: Dermatology Authors: Anton C De Groot, Howard I. Maibach Source Type: journals

Expression of hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha with progression of keratinocytic neoplasmsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Low oxygen levels are frequently encountered in solid tumors, and tumor growth, angiogenesis, invasion and metastasis are regulated by hypoxia-stimulated genes, such as hypoxia-inducible factors (HIFs) . Under low oxygen concentration, HIF-1alpha and HIF-2alpha translocate to the nucleus, heterodimerize with HIF-1beta, and activate target genes. High expression of HIFs has been correlated with frequent mutations of tumor suppressor genes such as p53 and PTEN, enhanced cellular proliferation, and decreased apoptosis . C-myc controls the G1-S cell-cycle transition and is overexpressed in many human tumors. HIF-1alpha is know...
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Xie Lining, Hiroshi Uchi, Sayaka Hayashida, Gaku Tsuji, Makiko Kido, Takeshi Nakahara, Satoshi Takeuchi, Masakazu Takahara, Yoichi Moroi, Masutaka Furue Tags: Letters to the Editor Source Type: journals

Olopatadine hydrochloride inhibits scratching behavior induced by a proteinase-activated receptor 2 agonist in miceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Proteinase-activated receptors (PARs), a group of G protein-coupled receptors, are activated by the cleavage of their N-terminal domain by serine proteinases . The proteolytic cleavage of the N-terminal region of PARs unmasks a new N-terminal sequence that acts as a tethered ligand that binds and activates the receptor itself . The PAR2 subtype is highly expressed in the skin, is activated by trypsin and mast cell tryptase, and can be activated without the need for proteolysis by synthetic PAR2 agonists, such as SLIGRL-NH2 . Tryptase and PAR2 are up-regulated on sensory nerves in the skin from atopic dermatitis patients . ...
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Ayumi Yoshizaki, Shinichi Sato Tags: Letters to the Editor Source Type: journals

Announcementsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Source Type: journals

Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-κB and MAPK pathwaysemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Our results indicate that nicotinamide inhibits IL-8 production through the NF-κB and MAPK pathways in an in vitro keratinocytes/P. acnes model of inflammation. Keratinocytes involved in the innate immune response may be a suitable target for treatment during the early phase of inflammation.
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Philippe A. Grange, Joël Raingeaud, Vincent Calvez, Nicolas Dupin Tags: Regular articles Source Type: journals

Cultured human melanocytes express functional Toll-like receptors 2–4, 7 and 9email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Present study indicates human melanocytes express a panel of functional TLRs. The ligation of TLRs can turn these cells into active players of the skin innate immunity.
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Ning Yu, Shujie Zhang, Fuguo Zuo, Kefei Kang, Ming Guan, Leihong Xiang Tags: Regular articles Source Type: journals

Histamine induces human β-defensin-3 production in human keratinocytesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: It is suggested that histamine induces hBD-3 production in human keratinocytes through H1 receptors by activating STAT3 and AP-1 via JAK2 and MEK/ERK. Histamine may promote cutaneous antimicrobial defense, inflammation, and wound repair through hBD-3.
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Takeko Ishikawa, Naoko Kanda, Carren S. Hau, Yayoi Tada, Shinichi Watanabe Tags: Regular articles Source Type: journals

Endogenous expression of TRPV1 channel in cultured human melanocytesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The vanilloid receptor 1 (transient receptor potential vanilloid type 1, TRPV1) is a non-selective cation channel that binds vanilloids and was originally described to be activated by the naturally occurring lipophilic alkaloid capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), a substance not synthesized in the human body . Recently, endogenous ligands including anandamide (arachidonylethanolamine) and lipoxygenases by-products such as 12-hydroperoxyeicosatetraenoic acid, N-arachidonyldopamine, and N-oleoyldopamine were also described to activate TRPV1 . Therefore, TRPV1 was suggested as a key integrator molecule of vari...
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Tae-Young Choi, Sang-Young Park, Ji Yoon Jo, Gun Kang, Jin Bong Park, Jin-Gu Kim, Seong-Geun Hong, Chang-Deok Kim, Jeung-Hoon Lee, Tae-Jin Yoon Tags: Letters to the Editor Source Type: journals

The first case report of a Chinese Hermansky–Pudlak syndrome patient with a novel mutation on HPS1 geneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Hermansky–Pudlak syndrome (HPS; OMIM 203300) is an autosomal recessive and a genetically heterogeneous disorder characterized by oculocutaneous albinism (OCA), bleeding tendency, and ceroid deposition which may cause lung fibrosis, colitis, and cardiomyopathy. Patients with HPS often die in their middle ages . The hallmark of pathological features of HPS is the disrupted biogenesis of lysosome-related organelles (LROs), such as melanosomes and platelet dense granules . The identification of the first HPS gene, HPS1, in 1996 prompts the identification of seven other HPS genes (HPS2–HPS8) during the past decade .
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Aihua Wei, Shi Lian, Lejin Wang, Wei Li Tags: Letters to the Editor Source Type: journals

Morphological relationship between nerve fibers and Langerhans cells in the epidermis of psoriasis vulgaris and lichen simplex chronicusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
It is generally accepted that skin is a target organ of the stress reaction . There is a close correlation between psoriasis vulgaris (PV), lichen simplex chronicus (LSC) and certain psychoneural factors. Both PV and LSC are associated with psychologic disorders and can be aggravated by anxiety or depression. Quantitative analysis of nerve fibers in the lesions of PV provides morphological evidence for the functional role of nervous system in PV . However, quantitative analysis of nerve fibers in the lesions of LSC and morphological relationship between nerve fibers and LCs in the lesions of PV and LSC have not been reported.
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Shaoshan Cui, Ting Xiao, Yan Wang, Hongguang Lu, Yakun Wang, Xing-Hua Gao, Huachen Wei, Hong-Duo Chen Tags: Letters to the Editor Source Type: journals

DNA damage responses in skin biology—Implications in tumor prevention and aging accelerationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: UV irradiation is the main etiological cause of most types of skin cancers and can accelerate skin photoaging. UV irradiation results in several types of DNA damage in eukaryotic cells, such as DNA single strand breaks, DNA interstrand cross-links, and nucleotide base modifications. In response to such DNA damages, mammalian cells exert DNA damage responses including cell cycle checkpoints, well-developed DNA repair, apoptosis and premature senescence to prevent genomic instability. Cell cycle checkpoints are important surveillance systems to maintain genomic integrity. Once checkpoint systems sense the abnormal ...
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Makoto Nakanishi, Hiroyuki Niida, Hiroshi Murakami, Midori Shimada Tags: Invited review article Source Type: journals

Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Rapamycin selectively blocks K6a expression in human keratinocytes. The improvement of symptoms in PC patients following rapamycin treatment suggests rapamycin (or rapamycin analogs) may be a therapeutic option, particularly if topical formulations can be developed that avoid the side effects associated with systemic administration.
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Robyn P. Hickerson, Devin Leake, Lana N. Pho, Sancy A. Leachman, Roger L. Kaspar Tags: Regular articles Source Type: journals

Effectiveness of different substrate materials for in vitro sunscreen testsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, several substrates have been fully characterized for in vitro sunscreen testing.Methods: The following different substrates have been utilised in the study: roughened PMMA plates, Transpore, Vitro-Skin, roughened quartz plate and a laboratory prepared roughened PTFE plate. The suitability of these substrates for SPF evaluation has been investigated by performing total absorbance measurements of seven sunscreen products with different SPF values produced by the same manufacturer.Results and conclusions: Application of sunscreen products on Transpore, roughened quartz plate, PMMA, PTFE and Vitro-Skin was perfo...
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Denis Garoli, Maria Guglielmina Pelizzo, Piergiorgio Nicolosi, Andrea Peserico, Elena Tonin, Mauro Alaibac Tags: Regular articles Source Type: journals

Eczema, respiratory allergies, and traffic-related air pollution in birth cohorts from small-town areasemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Background: Traffic-related air pollution (TAP) impairs respiratory health and could influence the development of allergies, as was demonstrated in urban areas with relatively high pollution. Whether eczema is affected by TAP was rarely investigated.Objective: To investigate whether exposure to TAP affects eczema and respiratory allergies also in small-town areas with lower concentrations of pollution.Methods: Between 1995 and 1999, we recruited 3390 newborns from small-town areas. Diagnoses and symptoms of eczema and respiratory allergies were recorded by annual questionnaires. Seventy-seven percent of families ...
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Ursula Krämer, Dorothea Sugiri, Ulrich Ranft, Jean Krutmann, Andrea von Berg, Dietrich Berdel, Heidrun Behrendt, Thomas Kuhlbusch, Matthias Hochadel, Heinz-Erich Wichmann, Joachim Heinrich, the GINIplus and LISAplus study groups Tags: Regular articles Source Type: journals

Editorial Boardemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Source Type: journals

The international role of the Japanese Society for Investigative Dermatology (JSID): Secretary General's Perspectiveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
After serving as the Editor-in-Chief of the Journal of Dermatological Science (JDS) for the past 5 years, I assumed the five-year Secretary Generalship of the JSID in 2008. With Prof. Yoshiki Tokura as the new president and Prof. Akimichi Morita as the new JDS Editor-in-Chief, I believe it is an appropriate time to consider the JSID's future. Together with increases in the quality and impact factor of the JDS, the JSID's international role on skin science has become clearer
Source: Journal of Dermatological Science - October 5, 2009 Category: Dermatology Authors: Hiroshi Shimizu Tags: Editorial Source Type: journals

Allopurinol-Induced DRESS Syndrome in an Adolescent Patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: A 16-year-old male patient, with a history of essential hypertension enrolled in an experimental drug protocol using allopurinol, presented to our emergency department with a 10-day history of fever. Initial laboratory evaluation revealed leukocytosis, eosinophilia, and transaminitis. After extensive work-up and exclusion of infectious and oncologic etiologies, the diagnosis of allopurinol-induced drug reaction and eosinophilia with systemic symptoms syndrome was carried out. The patient responded to administration of IV methylprednisolone, with complete resolution of symptoms and improvement of laboratory abnorm...
Source: Pediatric Dermatology - October 4, 2009 Category: Dermatology Authors: Ashvin K. Dewan, Ricardo A. Quinonez Source Type: journals