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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 25.
Double blind randomized pilot trial evaluating the efficacy of oral propranolol on infantile hemangiomas in infants less than 4 months of age
Since our report of the ability of propranolol to shrink alarming infantile hemangiomas (IHs) (1,2), propranolol has become the first line therapy for life threatening IHs (3‐5). Recently, a randomized clinical trial versus placebo has confirmed the safety and efficacy of 2mg/kg daily oral propranolol in children aged between 9 weeks and 5 years in focal and segmental IH (6). However, the latter study have focused on severe forms of IH, with sometimes a late onset of treatment in a heterogeneous population In the present monocentric pilot randomized, double‐blind, placebo controlled clinical trial, we tested the abilit...
Source: British Journal of Dermatology - January 10, 2013 Category: Dermatology Authors: C. Léauté‐Labrèze, E. Dumas la Roque, F. Nacka, A. Abouelfath, N. Grenier, M. Rebola, K. Ezzedine, N. Moore Tags: Correspondence Source Type: research
Humoral and cell‐mediated autoimmunity in lichen sclerosus
We read with great interest the paper of Edmonds et al. 1 who observed that men with penile lichen sclerosus (PLS) have significantly increased extracellular matrix protein 1 (ECM1) serum levels when compared to healthy controls (HC). Similar results were previously found in women with vulvar LS (VLS).2 Edmonds et al. 1 postulated that anti‐ECM1 antibodies are not the causative mechanism but present an epiphenomenon in LS. Nevertheless, there is evidence for humoral as well as cell‐mediated autoimmunopathogenic mechanisms driving LS.1‐5
Source: British Journal of Dermatology - January 10, 2013 Category: Dermatology Authors: T. Gambichler, D. Belz, S. Terras, A. Kreuter Tags: Correspondence Source Type: research
Ichthyosis vulgaris ‐ the filaggrin mutation disease
Abstract Ichthyosis vulgaris is caused by loss‐of‐function mutations in the filaggrin gene (FLG) and characterized clinically by xerosis, scaling, keratosis pilaris, palmar and plantar hyperlinearity, and a strong association with atopic disorders. According to published studies presented in this review article, FLG mutations are observed in approximately 7.7% of Europeans and 3.0% of Asians, but appear to be infrequent in darker‐skinned populations. This clinical review article provides an overview of ichthyosis vulgaris, epidemiology, related disorders and pathomechanisms. Not only does ichthyosis vulgaris possess ...
Source: British Journal of Dermatology - January 10, 2013 Category: Dermatology Authors: J.P. Thyssen, E. Godoy‐Gijon, P.M. Elias Tags: Review Article Source Type: research
Development of a Novel PCR‐ELISA Assay for the Diagnosis of Trichophyton rubrum Onychomycosis
In conclusion, we have optimized a target gene and DNA extraction method for rapid detection of T. rubrum onychomycosis.
Source: British Journal of Dermatology - January 10, 2013 Category: Dermatology Authors: F. Pankewitz, P. Nenoff, S. Uhrlaß, G. Bezold, I. Winter, Y. Gräser Tags: Original Article Source Type: research
Clinical and epidemiological comparison of patients affected by palmoplantar plaque psoriasis and palmoplantar pustulosis: a case‐series study
ConclusionsOur data suggest a close relationship between PPP and psoriasis. The existing data concerning epidemiology, clinical presentation, genetics, histopathology and pathogenesis do not permit a clear distinction between these two entities, which seem to coincide in many aspects. PPP appears to have a marked predilection among female smokers.
Source: British Journal of Dermatology - January 10, 2013 Category: Dermatology Authors: A.M.G. Brunasso, M. Puntoni, W. Aberer, C. Delfino, L. Fancelli, C. Massone Tags: Original Article Source Type: research
Digital compression of facial arteries facilitates cutaneous nasal surgery
Non‐melanoma skin cancers on the nose frequently present to dermatology for surgical excision. This anatomical area has an excellent vascular supply and, consequently, increased intra‐operative bleeding (Fig. 1 (a)). Pinching the nasal tip to control bleeding is commonly used, however this can be uncomfortable for the patient because the nasal septum may not be anaesthetised (Fig. 1 (b)).
Source: British Journal of Dermatology - January 10, 2013 Category: Dermatology Authors: B. Moran, C. Foley, P. Ormond Tags: Correspondence Source Type: research
Cholinergic Urticaria Responding to Botulinum Toxin injection for Axillary Hyperhidrosis
A 43 year old caucasion gentleman had been receiving Botulinum toxin type A injections (BOTOX®, Allergan) for his axillary hyperhidrosis since 2004 with good effect. In June 2009 he gave an 18 month history of developing small prutitic wheals on his chest, arms and to a lesser extent his legs and back.. The lesions lasted between 5 and 120mins. There was no dermographism. Triggers included anxiety, physical exercise and hot showers.
Source: British Journal of Dermatology - January 10, 2013 Category: Dermatology Authors: A. Sheraz, S. Halpern Tags: Correspondence Source Type: research
Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
Conclusions: Our findings implicate estrogens in the fibrotic process and may explain the preponderance of SSc in women. ICI or other ER signaling antagonists may be effective agents for the treatment of fibrosis.
Source: Arthritis Research and Therapy - January 10, 2013 Category: Rheumatology Authors: Keiko Aida-YasuokaChristine PeoplesHidekata YasuokaPamela HershbergerKatelynn ThielJane CauleyThomas MedsgerCarol Feghali-Bostwick Source Type: research
A new therapeutic option for facial seborrhoeic dermatitis: indole‐3‐acetic acid photodynamic therapy
Conclusion IAA‐PDT is a safe and effective therapeutic option for facial seborrhoeic dermatitis.
Source: Journal of the European Academy of Dermatology and Venereology - January 10, 2013 Category: Dermatology Authors: S.H. Kwon, M.Y. Jeong, K.C. Park, S.W. Youn, C.H. Huh, J.I. Na Tags: ORIGINAL ARTICLE Source Type: research
Tacrolimus abrogates TGF‐β1‐induced type I collagen production in normal human fibroblasts through suppressing p38MAPK signalling pathway: implications on treatment of chronic atopic dermatitis lesions
ConclusionsThe present results demonstrated that tacrolimus significantly inhibited physiological functions of fibroblasts enhanced by TGF‐β1 in vitro. Clinically, we propose that topical tacrolimus may not only reduce AD recurrence but also ameliorate dermal fibrosis often seen in chronic AD lesions.
Source: Journal of the European Academy of Dermatology and Venereology - January 10, 2013 Category: Dermatology Authors: C.‐C.E. Lan, A.‐H. Fang, P.‐H. Wu, C.‐S. Wu Tags: Original Article Source Type: research
Molecular microarray analysis reveals allergen‐ and exotoxin‐specific IgE repertoires in children with atopic dermatitis
ConclusionAllergenic molecule microarray analysis can be regarded as a suitable research tool for large‐scale IgE screening in infants and children with atopic dermatitis (AD). Still, further studies in well‐defined populations are needed to exactly identify its tangible benefits in the diagnostic and therapeutic management of affected patients in daily clinical practice.
Source: Journal of the European Academy of Dermatology and Venereology - January 10, 2013 Category: Dermatology Authors: H. Ott, S. Weißmantel, L.N. Kennes, H.F. Merk, J.M. Baron, R. Fölster‐Holst Tags: Original Article Source Type: research
Adult female acne: a new paradigm
This article reviews the specific characteristics of adult female acne, and provides recommendations for acne therapy in this patient group.
Source: Journal of the European Academy of Dermatology and Venereology - January 10, 2013 Category: Dermatology Authors: B. Dréno, A. Layton, C.C. Zouboulis, J.L. López‐Estebaranz, A. Zalewska‐Janowska, E. Bagatin, V.A. Zampeli, Y. Yutskovskaya, J.C. Harper Tags: REVIEW ARTICLE Source Type: research
Imaging actinic keratosis by high‐definition optical coherence tomography. Histomorphologic correlation: a pilot study
Abstract With the continued development of non‐invasive therapies for actinic keratosis such as PDT and immune therapies, the non‐invasive diagnosis and monitoring become increasingly relevant. High‐definition optical coherence tomography is a high‐resolution imaging tool, with micrometre resolution in both transversal and axial directions, enable to visualize individual cells up to a depth of around 570 μm filling the imaging gap between conventional optical coherence tomography and reflectance confocal microscopy. We sought to determine the feasibility of detecting and grading of actinic keratosis by this techn...
Source: Experimental Dermatology - January 10, 2013 Category: Dermatology Authors: Marc A. L. M. Boone, Sarah Norrenberg, Gregor B. E. Jemec, Veronique Marmol Tags: Original Article Source Type: research
Keratins and lipids in ethnic hair
Human hair has an important and undeniable relevance in society due to its important role in visual appearance and social communication. Hair is mainly composed of structural proteins, mainly keratin and keratin associated proteins, and lipids. Herein, we report a comprehensive study of the content and distribution of the lipids among ethnic hair, African, Asian and Caucasian hair. More interestingly, we also report the study of the interaction between those two main components of hair, specifically the influence of the hair internal lipids in the structure of the hair keratin. This was achieved by the use of a complete se...
Source: International Journal of Cosmetic Science - January 10, 2013 Category: Dermatology Authors: Célia F. Cruz, Margarida M. Fernandes, Andreia C. Gomes, Luisa Coderch, Meritxell Martí, Sandra Méndez, Luís Gales, Nuno G. Azoia, Ulyana Shimanovich, Artur Cavaco‐Paulo Tags: Original Article Source Type: research
Tibial artery calcification predicts foot ulceration
Tibial artery calcification is a significant risk factor for foot ulcers in patients with Type 2 diabetes, research suggests.
Source: MedWire News - Dermatology - January 9, 2013 Category: Dermatology Source Type: news
Arthritis Drugs May Trigger Shingles (CME/CE)
(MedPage Today) -- Patients with rheumatoid arthritis undergoing treatment with agents such as Enbrel (etanercept), Remicade (infliximab), or Humira (adalimumab) appear to have a significantly increased risk for developing shingles.
Source: MedPage Today Dermatology - January 9, 2013 Category: Dermatology Source Type: news
Photoprotective Properties of the Fluorescent Europium Complex in UV-Irradiated Skin
Skin Pharmacol Physiol 2013;26:76–84 (DOI:10.1159/000345976)
Source: Skin Pharmacology and Physiology - January 9, 2013 Category: Dermatology Source Type: research
Provectus Pharmaceuticals Announces H. Lee Moffitt Cancer Center Initiates Phase 1 Study Of PV-10 To Elucidate Bystander Effect
Provectus Pharmaceuticals, Inc. (OTCBB: PVCT), a development-stage oncology and dermatology biopharmaceutical company, reports that the Moffitt Cancer Center has initiated a Phase 1 study to investigate potential immune biomarkers in both tumor tissue and peripheral blood after intralesional ("IL") PV-10 injection of melanoma tumors. Amod Sarnaik, M.D. member of the Experimental Therapeutics Program at Moffitt and faculty member at the University of South Florida, is the principal investigator for the study, which is expected to enroll up to 15 subjects...
Source: Health News from Medical News Today - January 9, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
Novum Pharmaceutical Research Services Announces New Medical Director...
Novum Pharmaceutical Research Services has announced that Orin Goldblum, MD has joined its executive team as Medical Director of Dermatology and Locally Acting Products.(PRWeb January 08, 2013)Read the full story at http://www.prweb.com/releases/2013/1/prweb10299937.htm
Source: PRWeb: Medical Pharmaceuticals - January 9, 2013 Category: Pharmaceuticals Source Type: news
Multifocal Fixed Drug Eruption Probably Induced by Mefenamic Acid.
PMID: 23313442 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - January 9, 2013 Category: Dermatology Authors: Pérez-Pérez L, García-Gavín J, Allegue F, Zulaica A Tags: Actas Dermosifiliogr Source Type: research
Deep Vein Thrombosis in A Patient with Lepromatous Leprosy Receiving Thalidomide to Treat Leprosy Reaction.
We describe a case of deep vein thrombosis in a 43-year-old man with lepromatous leprosy who was being treated with thalidomide and prednisone for a type 2 leprosy reaction (erythema nodosum leprosum); the patient also had transiently positive antiphospholipid antibody results. We stress the importance of considering deep vein thrombosis, a potentially fatal complication, in dermatology patients treated with thalidomide. PMID: 23313443 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - January 9, 2013 Category: Dermatology Authors: Hebe Petiti-Martin G, Villar-Buill M, de la Hera I, Fuertes L, Burgués-Calderón M, Rivera-Díaz R, Vanaclocha F Tags: Actas Dermosifiliogr Source Type: research
Transient Myeloproliferative Syndrome Associated With Down Syndrome.
PMID: 23313444 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - January 9, 2013 Category: Dermatology Authors: Borregón P, Menárguez J, Navarro N, Campos M Tags: Actas Dermosifiliogr Source Type: research
Ulceras Dolorosas en Lengua.
PMID: 23313445 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - January 9, 2013 Category: Dermatology Authors: Escoda M, Gardiello M, Muntané MJ Tags: Actas Dermosifiliogr Source Type: research
Changes in IL-10 and specific antibodies associated to successful Dermatophagoides pteronyssinus immunotherapy in children during the first year of treatment.
PMID: 23313160 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - January 9, 2013 Category: Allergy & Immunology Authors: Boquete-París M Tags: Allergol Immunopathol (Madr) Source Type: research
Analysis of the association between air pollution and allergic diseases exposure from nearby sources of ambient air pollution within elementary school zones in four Korean cities.
In this study, seven elementary schools were selected and they were classified into three categories. The selection included one school with no traffic-related or other pollutants, three with traffic-related pollutants, and three with traffic-related and other pollutants from industrial and filling station sources. The ISAAC questionnaire survey was given to all of the students except to those in the 1st grade who were presumed to be less likely to be exposed to the school environment than the remainder of the students attending those seven schools. The assessment of allergic disease was conducted on a total of 4,545 stude...
Source: Environmental Science and Pollution Research International - January 9, 2013 Category: Environmental Health Authors: Kim HH, Lee CS, Jeon JM, Yu SD, Lee CW, Park JH, Shin DC, Lim YW Tags: Environ Sci Pollut Res Int Source Type: research
Dermatan sulfate synergizes with heparin in murine sperm chromatin decondensation.
Abstract The mammalian sperm nucleus contains an unusually condensed chromatin, due to replacement of the majority of histones by protamines. However, soon after the spermatozoon penetrates the ooplasm at fertilization, decondensation of this densely packed chromatin must occur to allow formation of the male pronucleus and syngamy. Decondensation is accomplished by protamine disulfide bond reduction by oocyte glutathione and replacement of protamines by oocyte histones with the aid of an acceptor molecule. Previous results from our laboratory have demonstrated that heparan sulfate (HS) present in the ooplasm functi...
Source: Systems Biology in Reproductive Medicine - January 9, 2013 Category: Reproduction Medicine Authors: Sanchez MC, Sedo CA, Julianelli VL, Romanato M, Calvo L, Calvo JC, Fontana VA Tags: Syst Biol Reprod Med Source Type: research
Prevention, recognition and treatment of dry skin conditions.
Abstract Dry skin is common and impacts on wound healing, the severity of other skin disorders, such as inflammatory dermatoses, and on the patient's quality of life. Dry skin may delay wound healing, especially in patients with venous leg ulcers and those with pressure ulcers. The aim of this review was to help clinicians recognise where dry skin may impact on patient management in general and on the patient's quality of life. The review addresses causes of dry skin and the impact dry skin can have on patients. The presentation of dry skin is discussed and a classification tool for dry skin is proposed. Prevention...
Source: British Journal of Nursing - January 9, 2013 Category: Nursing Authors: Andriessen A Tags: Br J Nurs Source Type: research
Efficacy and Safety of a Novel Botulinum Toxin Type A Product for the Treatment of Moderate to Severe Glabellar Lines: A Randomized, Double‐Blind, Active‐Controlled Multicenter Study
ConclusionNBoNT is equally as effective as OBoNT for the treatment of glabellar frown lines. Both toxins were well tolerated.
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Chong H. Won, Hyung M. Lee, Woo S. Lee, Hoon Kang, Beom J. Kim, Won S. Kim, Ju H. Lee, Dong H. Lee, Chang H. Huh Tags: Original Article Source Type: research
A New Botulinum Toxin Potentially Bioequivalent to OnabotulinumtoxinA: Are There Any Differences at All?
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Gi‐Hyeok Yang, Hyun Ho Jung Tags: Mini Review Source Type: research
Comparative Study of Biological Activity of Four Botulinum Toxin Type A Preparations in Mice
ConclusionThe dose‐conversion ratio between onabotulinumtoxinA and abobotulinumtoxinA was determined to be 1:2.6; previous reports of 1:3 were considered too high. A dose‐conversion ratio between onabotulinumtoxinA and new botulinum toxin of 1:1 was deemed appropriate. OnabotulinumtoxinA and incobotulinumtoxinA demonstrated a dose‐conversion ratio of 1:1.07. The efficacy of incobotulinumtoxinA was slightly lower than that of onabotulinumtoxinA. These dose‐conversion ratios are applicable solely from an efficacy standpoint and not for safety. This study was conducted in mice, so it may not translate perfectly to human applications.
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Myung Eun Chung, Dae Heon Song, Joo Hyun Park Tags: Original Article Source Type: research
A Pharmacodynamic Comparison Study of Different Botulinum Toxin Type A Preparations
ConclusionNeu‐BoNT/A and ona‐BoNT/A may be interchangeable based on a simple dose ratio.
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Sung‐Beom Kim, Bhupal Ban, Keun‐Suk Jung, Gi‐Hyeok Yang Tags: Original Article Source Type: research
Spectrum of skin changes secondary to insulin injections in Type 1 diabetes mellitus patients
Source: Journal of the European Academy of Dermatology and Venereology - January 9, 2013 Category: Dermatology Authors: G.U. Sawatkar, A.J. Kanwar, S. Dogra, S.K. Bhadada, D. Dayal Tags: LETTER TO THE EDITOR Source Type: research
Galderma to acquire Spirig
Pharmaceutical company Galderma is poised to acquire Spirig Pharma, a move that will boost its line of products for treating various dermatologic conditions.
Source: Modern Medicine - January 9, 2013 Category: Journals (General) Source Type: news
Cellular versus acellular matrix devices in treatment of diabetic foot ulcers: study protocol for a comparative efficacy randomized controlled trial
DiscussionIf our hypothesis is correct, then immense cost savings could be realized by using the orders-of-magnitude less expensive acellular ECM device without compromising patient health outcomes. The article describes the protocol proposed to test our hypothesis.Trial registration: ClinicalTrials.gov: NCT01450943. Registered: 7 October 2011
Source: Trials - January 9, 2013 Category: Journals (General) Authors: Hadar Lev-TovChin-Shang LiSara DahleRoslyn Isseroff Source Type: research
Measurement of stress–strain behaviour of human hair fibres using optical techniques
In this study, a more accurate ‘true’ stress–strain curve of human hair was determined by applying optical techniques to the images of the hair deformed under tension. This was achieved by applying digital image cross‐correlation (DIC) to 10× magnified images of hair fibres taken under increasing tension to estimate the strain increments. True strain was calculated by summation of the strain increments according to the theoretical definition of ‘true’ strain. The variation in diameter with the increase in longitudinal elongation was also measured from the 40× magnified images to estimate the Poisson's ratio a...
Source: International Journal of Cosmetic Science - January 9, 2013 Category: Dermatology Authors: J. Lee, H. J. Kwon Tags: Original Article Source Type: research
Letter: Immunocryotherapy for Difficult‐to‐Treat Basal Cell Carcinoma of the Eyelid
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Zoe Apalla, Anatoli Karteridou, Aimilios Lallas, Elena Sotiriou, Thrasivoulos Tzellos, Dimitrios Varytimiadis, Ioanna Lefaki Tags: LETTER Source Type: research
Letter: Comment on Basal Cell Carcinoma of the Scrotum: Clinicopathologic Analysis of 10 Cases
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Oscar SuÁrez‐Amor Tags: LETTER Source Type: research
Letter: Photodynamic Therapy with Methyl‐Aminolevulinate for the Treatment of Double Extramammary Paget's Disease
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Maria I. Longo‐Imedio Tags: LETTER Source Type: research
Commentary: Serum Lidocaine Levels and Cutaneous Side Effects After Application of 23% Lidocaine/7% Tetracaine Ointment to the Face
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: Joseph F. Sobanko Tags: COMMENTARY Source Type: research
Commentary: Inflammation and Fibrosis: Pitfalls for the Mohs Surgeon
Source: Dermatologic Surgery - January 9, 2013 Category: Dermatology Authors: John K. Geisse Tags: COMMENTARY Source Type: research
Gefitinib: Erosive pustular dermatosis of the scalp-like eruption with alopecia in an elderly patient: case report
Source: Reactions - January 8, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Atlas of Trichoscopy
Dermoscopy in Hair and Scalp DiseaseTrichoscopy – the use of dermoscopy to diagnose diseases of hair and scalp – was initially named in 2006 and thus it is still very much in its childhood. With so much still to learn in the great field of hair and scalp disorders, recent years have brought multiple results from original studies into trichoscopy, new case descriptions, and analytic reviews, as well as know-how derived from ...
Source: Springer Medicine titles - January 8, 2013 Category: Databases & Libraries Tags: Dermatology Source Type: news
Long-term efficacy of a single-dose Radio Frequency Heat therapy versus intralesional antimonials for cutaneous leishmaniasis in India.
CONCLUSIONS: A single application topical RFH therapy was safe, cosmetically acceptable and effective in inducing long-term cure of CL. PMID: 23298394 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - January 8, 2013 Category: Dermatology Authors: Bumb RA, Prasad N, Khandelwal K, Aara N, Mehta RD, Ghiya BC, Salotra P, Wei L, Peters S, Satoskar AR Tags: Br J Dermatol Source Type: research
In vivo pharmacokinetics and in vitro antifungal activity of iodiconazole, a new triazole, determined by microdialysis sampling
In this study, the distribution of a new triazole drug, iodiconazole, in rat dermal interstitial fluid and blood was investigated by double-site microdialysis following dermal administration. It was demonstrated that well-calibrated microdialysis sampling in rats could be used to assess the percutaneous penetration kinetics of iodiconazole cream. Iodiconazole penetrated rapidly and cleared slowly from the dermis. The ratio of area under the concentration–time curve in dermis (AUCdermis) to that in blood (AUCblood) was close to 20, which meant that the free iodiconazole concentration had a higher distribution in the targe...
Source: International Journal of Antimicrobial Agents - January 8, 2013 Category: Drugs & Pharmacology Authors: Ning Sun, Ying Xie, Chunquan Sheng, Yongbing Cao, Wannian Zhang, Hongzhuan Chen, Guorong Fan Tags: Full length articles Source Type: research
Host plant adaptation and pesticide resistance [Agricultural Sciences]
Plants produce a wide range of allelochemicals to defend against herbivore attack, and generalist herbivores have evolved mechanisms to avoid, sequester, or detoxify a broad spectrum of natural defense compounds. Successful arthropod pests have also developed resistance to diverse classes of pesticides and this adaptation is of critical importance to...
Source: Proceedings of the National Academy of Sciences - January 8, 2013 Category: Science Authors: Dermauw, W., Wybouw, N., Rombauts, S., Menten, B., Vontas, J., Grbic, M., Clark, R. M., Feyereisen, R., Van Leeuwen, T. Tags: PNAS Plus Source Type: research
Atherosclerotic cardiovascular disease and dermatomyositis: an analysis of the Nationwide Inpatient Sample survey
Patients suffering from both dermatomyositis and an atherosclerotic cardiovascular disease (CVD) are twice as likely to die during inpatient stay compared to controls with CVD, and dermatomyositis patients without CVD.
Source: Arthritis Research and Therapy - January 8, 2013 Category: Rheumatology Authors: Eleni LinosDavid FiorentinoBharathi LingalaEswar KrishnanLorinda Chung Source Type: research
Can acitretin be given to patients with renal impairment or patients on renal replacement therapies?
Source: South West Medicines Information and Training Area: Evidence > Medicines Q & A There are very few data to support the use of acitretin in patients with renal impairment (RI) or in those undergoing renal replacement therapy (RRT) and further studies are needed. The information that is available is conflicting. Acitretin should only be prescribed by, or under the supervision of a dermatological specialist. The decision to prescribe acitretin to a patient with RI or on RRT lies with the physician and should be based on an appropriate assessment of the likely risk versus benefit ratio. If acitretin is prescribed...
Source: NeLM - Medicines Q and A - January 8, 2013 Category: Drugs & Pharmacology Source Type: news