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Cytotoxic activity of diterpenes and extracts of juniperus brevifoliaemail this article save this article to My Clippings discuss this articlediscuss this article
Planta MedDOI: 10.1055/s-2008-1074529AbstractThe hexane, dichloromethane, acetone and ethanol extracts of the leaves, bark and wood of were subjected to screening against human tumour cells lines from the cervix (HeLa) and larynx (Hep-2) in two different stages of the cell cycle. The dichloromethane and the chloroform-soluble portions of the acetone extracts of the leaves were active against both tumour cell lines. Chemical investigation of one of the most active extracts (dichloromethane extract from leaves) by preparative chromatography afforded compounds . Among these, compounds were isolated for the first time from the...
Source: Planta Medica - May 17, 2008 Category: Drugs & Pharmacology Source Type: journals

Anticomplementary activity of triterpenoids from the whole plant of aceriphyllum rossii against the classical pathwayemail this article save this article to My Clippings discuss this articlediscuss this article
Planta MedDOI: 10.1055/s-2008-1074534AbstractTo provide a better understanding of the anti-complement activity of triterpenoids, seven unusual pentacyclic triterpenoids bearing a carboxyl group at C-27 were evaluated for their anticomplement activities against the classical pathway of the complement system. The triterpenoids were isolated from the whole plant of of the family Saxifragaceae and were determined to be 3α,23-isopropylidenedioxyolean-12-en-27-oic acid (), 3-oxoolean-12-en-27-oic acid (), 3α-hydroxyolean-12-en-27-oic acid (), β-peltoboykinolic acid (), 3α,23-diacetoxyolean-12-en-27-oic acid (...
Source: Planta Medica - May 17, 2008 Category: Drugs & Pharmacology Source Type: journals

Glucuronidated metabolites of the flavonoid quercetin do not auto-oxidise, do not generate free radicals and do not decrease nitric oxide bioavailabilityemail this article save this article to My Clippings discuss this articlediscuss this article
Planta MedDOI: 10.1055/s-2008-1074525AbstractQuercetin, the most abundant flavonoid in the diet, reduces blood pressure and restores endothelial dysfunction in hypertensive animals. However, quercetin (as the aglycone) is usually not present in plasma, but it is rapidly metabolised during absorption by methylation, glucuronidation and sulfation. Depending on the experimental conditions, quercetin can show anti-oxidant or pro-oxidant effects. We have analysed the pro-oxidant effects of quercetin and its methylated (3-methylquercetin or isorhamnetin), sulfated (quercetin 3′-sulfate), glucuronidated (quercetin 3-glucuro...
Source: Planta Medica - May 17, 2008 Category: Drugs & Pharmacology Source Type: journals

Madecassoside isolated from centella asiatica herbs facilitates burn wound healing in miceemail this article save this article to My Clippings discuss this articlediscuss this article
Planta MedDOI: 10.1055/s-2008-1074533AbstractThe current study was designed to investigate the effect of madecassoside, the major triterpene in , on burn wound healing and its possible mechanism of action. An oral administration of madecassoside (6, 12, 24 mg/kg) facilitated wound closure in a time-dependent manner and reached its peak effect, nearly completely wound closure, on day 20 in the group receiving the highest dose of 24 mg/kg of madecassoside. Further histopathological analysis revealed that madecassoside alleviated infiltration of inflammatory cells as well as enhanced epithelisation resulting from dermal proli...
Source: Planta Medica - May 17, 2008 Category: Drugs & Pharmacology Source Type: journals

Growth inhibition of a spectrum of bacterial and fungal pathogens by sulforaphane, an isothiocyanate product found in broccoli and other cruciferous vegetablesemail this article save this article to My Clippings discuss this articlediscuss this article
Planta MedDOI: 10.1055/s-2008-1074520AbstractIn addition to its documented antitumor effects, previous and infectivity experiments have shown that sulforaphane (SFN), an isothiocyanate compound found abundantly in broccoli and other cruciferous vegetables, inhibits the growth of the bacterial pathogen No recent evidence exists, however, on the possible microbial activity of SFN against a broader range of microorganisms, including those that may develop resistance to conventional antibiotics. The aim of this study was to determine the susceptibility patterns of SFN against a wide variety of bacterial and fungal pathogens. S...
Source: Planta Medica - May 17, 2008 Category: Drugs & Pharmacology Source Type: journals

Chemotaxonomic study of medicinal taxus species with fingerprint and multivariate analysisemail this article save this article to My Clippings discuss this articlediscuss this article
Planta MedDOI: 10.1055/s-2008-1074531AbstractSpecies delimitation in has been controversial and it is very difficult to distinguish yew materials by their morphological characters. In this paper, a valid HPLC fingerprinting method coupled with multivariate analysis was used to define a framework for species identification and classification. Fingerprint-based similarity was employed for a chemotaxonomic study by hierarchical clustering analysis (HCA) and principal component analysis (PCA). Based on the PCA loadings, twelve chemical constituents were selected as chemotaxonomic markers which can be used to establish a more p...
Source: Planta Medica - May 17, 2008 Category: Drugs & Pharmacology Source Type: journals

Zaleplon: hallucinations and illusions: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 35 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Venlafaxine overdose: fatal heart arrest: 2 case reports.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 34 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Vitamin d analogues overdose: hypercalcaemia and nephrocalcinosis in infants, treated with alendronic acid: 2 case reports.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 34 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Vitamin d analogues abuse: hypercalcaemia and renal failure: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 34 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Venlafaxine: anticholinergic-type symptoms following accidental administration: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 33 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Venlafaxine: increased libido and spontaneous orgasms: 3 case reports.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 33 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Valproic acid: haematological disorders: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 33 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Trastuzumab: first report of ectopic pregnancy: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 32 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Sulpiride: hyperprolactinaemia and sexual function disorders, treated with aripiprazole: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 32 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Tioguanine: portal hypertension, variceal haemorrhage and nodular hyperplasia: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 32 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Sirolimus: kidney disorders: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 31 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Squaric acid dibutylester: contact dermatitis leading to dle exacerbation: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 31 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Spiramycin/metronidazole: anaphylaxis (first report with metronidazole): case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 31 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Solanaceous alkaloids: central diabetes insipidus: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 31 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Pyridoxine: severe sensorimotor neuropathy following excessive use in an elderly patient: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 30 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Salbutamol: first report of anaphylaxis: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 30 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Sertraline: serotonin syndrome in an elderly patient: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 30 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Risperidone: tic treated with aripiprazole: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 30 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Pregabalin: first report of neutropenia: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 29 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Prednisone: exacerbation of kaposi's sarcoma: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 29 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Potassium bromide: bromoderma in a child: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 29 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Pioglitazone: mitral valve regurgitation: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 28 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Peginterferon-[alpha]-2a: maculopapular eruption: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 28 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Oxycodone: first report of cholestatic hepatitis: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 27 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Opioid analgesics: apnoea, bradycardia and decreased respiratory rates in paediatric patients: 3 case reports.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 27 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Pamidronic acid/zoledronic acid: osteonecrosis of the jaw: 8 case reports.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 27 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Orlistat: calcium oxalate crystalluria and acute tubular necrosis?: 2 case reports.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 27 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Nevirapine overdose: neutropenia and hyperlactataemia in a neonate: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 26 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Morphine overdose: miosis, consciousness disorders and respiratory insufficiency in an elderly patient: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 26 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Modafinil: short manic-like episodes: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 26 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Mivacurium chloride: apnoea in a patient with cholinesterase ii deficiency, treated by plasma transfusion: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 25 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Minoxidil: stevens-johnson syndrome: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 25 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Mifepristone/misoprostol: first report of mobius syndrome in a neonate following in utero exposure: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 25 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Magnesium oxide abuse: quadriparesis (first report), secondary to hypermagnesaemia: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 24 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Mefloquine: psychotic mania: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 24 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Meglumine antimonate: eczema and anaphylaxis following topical and intramuscular administration: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 24 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Metoprolol/paroxetine interaction: complete atrioventricular block: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 24 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Lithium/tamoxifen: depression in a patient with bipolar disorder: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 23 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Lithium/ziprasidone interaction: hyperprolactinaemia and galactorrhoea: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 23 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Lithium/antiepileptic drugs/naproxen/aripiprazole/memantine interaction: cognition disorders: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 23 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Levofloxacin/norfloxacin: recall urticaria: 2 case reports.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 22 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Lithium: lingual thyroid enlargement: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 22 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Isoflavones: pseudolymphoma: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 22 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Lithium: hypercalcaemia and hypoparathyroidism leading to delirium: case report.email this article save this article to My Clippings discuss this articlediscuss this article
Page: 22 (Source: Reactions Weekly)
Source: Reactions Weekly - May 17, 2008 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

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