Drugs & Pharmacology 
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Mushrooms as therapeutic agents
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Mushrooms have been known for their nutritional and culinary values and used as medicines and tonics by humans for ages. In modern terms, they can be considered as functional foods which can provide health benefits beyond the traditional nutrients. There are monographs that cover the medicinal and healing properties of some individual traditional mushrooms. There has been a recent upsurge of interest in mushrooms not only as a health food which is rich in protein but also as a source of biologically active compounds of medicinal value which include complementary medicine/dietary supplements for anticancer, antiviral, hepat...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Chemical study and anti-inflammatory activity of Capsicum chacoense and C. baccatumEmail this article to a colleague.
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Capsicum species, Solanaceae, have been used for centuries as food additives by populations of different regions of the world. Capsaicin (trans-methyl-N-vainillyl-nonenamide) is the main pungent compound extracted from the red hot pepper fruit (Capsicum spp.). The capsaicin content was determined by means of a HPLC method. The results showed that Capsicum chacoense Hunz., contains similar amounts of capsaicin (13.9 mg/100 g of dry fruit) in comparison with Capsicum baccatum L. (12.6 mg/100 g) and Capsicum annum L. (10.1 mg/100 g). Dichloromethane (CH2Cl2) and ethanol (EtOH) extracts of C. chacoense elicited a 46% and 38 % ...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Chemical constituents of Rourea donianaEmail this article to a colleague.
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The chromatography fractionation of the hexane, chloroform and ethyl acetate extracts from the leaves and stems of Rourea doniana Baker, Connaraceae, resulted in the isolation of five triterpenes (lupeol, lupenone, α-amyrenone, β-amyrenone, and taraxerol), a flavonol (7,4'-dimethylkaempferol), a coumarin (scopoletin) and four phytosteroids (β-sitosterol, stigmasterol, β-sitosteryl-3-O-β- D-glucopyranoside and stigmasteryl-3-O-β-D-glucopyranoside). All compounds are being for the first time in this species and all triterpenes and the flavonol are being described for the first time in the family Connaraceae. These comp...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Phytochemical screening, antinociceptive and anti-inflammatory activities of Chrysopogon zizanioides essential oilEmail this article to a colleague.
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Chrysopogon zizanioides (L.) Roberty, Poaceae, is a plant widely used in northeast Brazil in folk medicine for the treatment of various pathological conditions, including inflammatory pain. The present study evaluated the antinociceptive and anti-inflammatory effects of C. zizanioides essential oil (EO) in rodents. EO was further characterized by GC/MS. The major components of EO were identified as khusimol (19.57%), E-isovalencenol (13.24%), α-vetivone (5.25%), β-vetivone (4.87%) and hydroxy-valencene (4.64%). Following intraperitoneal injection (i.p.), EO at 50 and 100 mg/kg significantly reduced the number of writhes ...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Erythroxylum pungens elicits vasorelaxation by reducing intracellular calcium concentration in vascular smooth muscle cells of ratsEmail this article to a colleague.
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The cardiovascular effects elicited by the ethanolic extract obtained from the roots of Erythroxylum pungens O.E. Schulz, Erythroxylaceae (EEEP) and the vasorelaxant effect induced by its main tropane alkaloid (pungencine) were investigated. In normotensive rats, administration of EEEP (1, 10, 30 and 60 mg/kg i.v., randomly) produced dose-dependent hypotension (-2±1, -7±0.5 -17.6±1, -24±1 Δ mmHg, n=5) followed by tachycardia (3±0.5, 7±2, 7.1±1, 10±5 Δ bpm, n=5). In intact phenylephrine (Phe, 10 µM)-pre-contracted rings, EEEP (0.01-500 µg/mL) induced concentration-dependent vasorelaxation (EC50 13.7±5.5 µg/mL,...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Attenuating effect of seeds of Adenanthera pavonina aqueous extract in neuropathic pain in streptozotocin-induced diabetic rats: an evidence of neuroprotective effectsEmail this article to a colleague.
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The aim of present study was to investigate the attenuating effects of Adenanthera pavonina L., Leguminosae-Mimosaceae seeds aqueous extract (APSAE), in streptozotocin (STZ)-induced diabetic neuropathy in rats. APSAE (50, 100 and 200 mg/kg per day) was given to diabetic rats for twelve weeks. Cold and hot water tail immersion tests, photoactometer and Rota-rod tests were performed to assess degree of colder, thermal, spontaneous motor activity and motor co-ordination changes respectively at different time intervals i.e., week 0, 4, 8 and 12. Tissue superoxide anion and total calcium levels were determined after twelve week...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Evaluation of wound healing activity of Ammannia baccifera and Blepharis maderaspatensis leaf extracts on ratsEmail this article to a colleague.
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Wound healing activity of the leaf extracts of Ammannia baccifera L., Lythraceae, and Blepharis maderaspatensis (L.) B.Heyne ex Roth., Acanthaceae, was investigated by excision and incision wound healing models in rats. A phytochemical screening was done to determine the major constituents of the chloroform, ethyl acetate and ethanolic fractions of ethanolic leaf extracts. The excision and incision models were used to assess the effect of the plant extracts on wound healing in rats. Phytochemical screening reveals the presence of tannins, saponins, steroids, terpenoids, and flavonoids in the extract. The wound healing effe...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Evaluation of hepatoprotective activity of aqueous and ethanolic extract of Oxalis corniculata against intoxication of thioacetamide induced ratsEmail this article to a colleague.
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The present study was carried out to evaluate the hepatoprotective activity of aqueous and ethanolic leaves extracts of Oxalis corniculata L., Oxalidaceae, against thioacetamide-induced hepatotoxicity. Hepatotoxicity was induced in Wistar rats of either sex by subcutaneous injection of thioacetamide. An aqueous and ethanolic extract of aerial parts of O. corniculata (200 and 400 mg/kg/day) were evaluated. Oral administration of O. corniculata aqueous and ethanolic leaves extract at 400 mg/kg resulted in a significant reduction in SGOT (146.42±2.54 and 136.75±1.37 IU/L respectively), SGPT (81.96±3.15 and 72.05±2.33 IU/L...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Reversal of CRF- and stress-induced anorexia by an ayurvedic formulationEmail this article to a colleague.
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Trikatu churna is one of the commonly used Ayurvedic formulations in the traditional system of medicine in India for the treatment of agnimandya, i.e. anorexia. Trikatu contains equal amounts of finely powdered rhizomes of Zingiber officinale Roscoe (Zingiberaceae) and fruits of Piper longum L. and Piper nigrum L. (Piperaceae). The chief objective of the study was to determine the antianorectic effects of three drugs individually and to compare these effects with the effect of Trikatu. The activity of the drugs was studied after anorexia was induced in rats by (1) physical stress arising from immobilization for 60 min; (2)...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Healing potential of Iranian traditional medicinal plants on burn wounds in alloxan-induced diabetic ratsEmail this article to a colleague.
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Malva sylvestris, Punica granatum, Amygdalus communis, Arnebia euchroma and Scrophularia deserti are important medicinal plants in Iranian traditional medicine (Unani) whose have been used as remedy against edema, burn, and wound and for their carminative, antimicrobial and anti-inflammatory activities. The ethanol extracts of M. sylvestris and P. granatum flowers, A. communis leaves, A. euchroma roots and S. deserti stems were used to evaluate the burn healing activity in alloxan-induced diabetic rats. Burns were induced in Wistar rats divided into nine groups as following; Group-I: normal rats were treated with simple oi...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
The antigenotoxic activity of latex from Himatanthus articulatusEmail this article to a colleague.
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Himatanthus articulatus (Vahl) Woodson (Apocynaceae) is a native plant to the Amazon popularly used to treat ulcers, tumors, inflammations, cancer, syphilis and malaria. The aim of the present study was to investigate the in vivo genotoxic/antigenotoxic and mutagenic potential of this plant, using the comet and the micronucleus assays in mice. Female and male adult mice were treated with different doses of H. articulatus latex by gavage for two consecutive days. For the experiments, the latex was serially diluted with water to 1:2 (D1); 1:4 (D½) and 1:8 (D¼) and administered to the animals. The blood slides were exposed ...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Anti-tumor activity of the methanolic extracts of Salvia menthifoliaEmail this article to a colleague.
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In the present research we investigated the anti-proliferative activity of Salvia menthifolia Ten. (formerly Salvia menthaefolia), Lamiaceae, on a glioblastoma cell line, since up to date poor therapeutic results have been reported for treatment of malignant glioblastoma. Methanol extracts from different anatomical parts of S. menthifolia were tested on DBTRG-05MG cell line by MTT assay. The most active primary stems extract was also evaluated for apoptosis induction. Results confirmed the anti-tumor property of all the organs and demonstrated that the primary stems extract induced apoptosis after 4 h with the highest valu...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Anticholinesterase activity evaluation of alkaloids and coumarin from stems of Conchocarpus fontanesianusEmail this article to a colleague.
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Conchocarpus fontanesianus (A. St.-Hill.) Kallunki & Pirani, Rutaceae, popularly known as pitaguará, is a native and endemic tree from São Paulo and Rio de Janeiro States, Brazil. Based in the information that anticholinesterasic derivatives could act as new prototypes to treatment of Alzheimer disease, this work describes the fractionation guided by evaluation of the anticholinesterase activity of the ethanolic stems extract from C. fontanesianus. This procedure afforded the alkaloids dictamnine (1), γ-fagarine (2), skimianine (3), and 2-phenyl-1-methyl-4-quinolone (4), as well as the coumarin marmesin (5). (Source: Re...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Effect of Arrabidaea chica extracts on the Ehrlich solid tumor developmentEmail this article to a colleague.
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In conclusion, the ethanol and aqueous extracts of A. chica have immunomodulatory and antitumor activities attributed to the presence of flavonoids, such as kaempferol. These effects appear to be related to different mechanisms of action for each extract. This study demonstrates the potential of A. chica as an antitumor agent confirming its use in traditional popular medicine. (Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Effect of petroleum ether and ethanol fractions of seeds of Abrus precatorius on androgenic alopeciaEmail this article to a colleague.
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Seeds of Abrus precatorius L., Fabaceae, are commonly used as purgative, emetic, aphrodisiac and in nervous disorder in traditional and folk medicines. In present study petroleum ether and ethanolic extracts of A. precatorius seeds are evaluated for reversal of androgen (testosterone by i.m route) induced alopecia in male albino wistar rats and compared to topical administration of standard antiandrogenic drug finasteride for 21 days. The results were reflected from visual observation and histological study of several skin sections via various parameters as anagen to telogen ratio and follicle density/mm area of skin surfa...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Metabolic and biological prospecting of Coreopsis tinctoriaEmail this article to a colleague.
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Coreopsis tinctoria Nutt., Asteraceae, flowering tops infusion has been traditionally used in many countries to control hyperglycaemia. In this work we report for the first time fatty acids and volatile compounds in this species. Fifteen fatty acids and sixteen volatile compounds were determined by GC-ITMS, being saturated fatty acids and monoterpenes the main compounds. The antioxidant and antibacterial potential of this matrix was checked for the first time by several in vitro assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Antibacterial capacity was assessed aga...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Effect of a plant origin drug on the biodistribution of 99mTc-DTPA in Wistar albino ratsEmail this article to a colleague.
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In recent years all over the world, medicinal plants are used quite a lot but side effects of biological and chemical contents and radiopharmaceutical interactions for each consumer in question aren't entirely well-known. The studies of plant origin drug interaction with radiopharmaceuticals are highly relevant and desired. One of them is passiflora syrup (Passiflora incarnata L., Passifloraceae) which is widely used for depression, insomnia, anxiety and menopause period. The aim of current study is to evaluate possible effects of passiflora syrup on the biodistribution of 99mTc-DTPA and its blood cells uptake. DTPA was la...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Syzygium aromaticum extracts as good source of betulinic acid and potential anti-breast cancerEmail this article to a colleague.
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This study aims to investigate the anti-breast cancer effect of extracts from leaves, stem and bark of S. aromaticum and to develop a method for preparation of betulinic acid fraction from the leaves. Betulinic acid, ursolic acid and oleanolic acid contents of the extracts were determined by HPLC. A betulinic acid fraction was prepared by simple crystallization of leaves extract and was characterized by HPLC and mass analysis. Anti-breast cancer effects were studied on MCF-7 and MDA-MB-231 cells. The extracts were found to contain high levels of betulinic acid particularly the leaves extract which contained 17% wt/wt. The ...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Polyphenols of Mangifera indica modulate arsenite-induced cytotoxicity in a human proximal tubule cell lineEmail this article to a colleague.
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Inorganic arsenic is an ubiquitous environmental contaminant able to cause severe pathologies in humans, including kidney disorders. The possible protective effects of Mangifera indica L., Anacardiaceae, stem bark extract (MSBE) and some mango phenols on the cytotoxicity of arsenite (AsIII) in the proximal tubule cell line HK-2 was investigated. In cells cultured for 24 h in presence of AsIII, a dose-dependent loss of cell viability occurred that was significantly alleviated by MSBE, followed by gallic acid, catechin and mangiferin. Mangiferin complexed with Fe+++ proved more efficacious than mangiferin alone. MSBE and pur...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Chemical constituents and evaluation of the toxic and antioxidant activities of Averrhoa carambola leavesEmail this article to a colleague.
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The liquid-liquid partitioning of a crude hydroalcoholic extract of Averrhoa carambola L., Oxalidaceae, leaves led to the isolation of a sterol and three flavone C-glycosides. From the n-hexane fraction β-sitosterol was isolated and from the ethyl acetate fraction apigenin-6-C-β-L-fucopyranoside (1) and apigenin6-C-(2"-O-α-L-rhamnopyranosyl)-β-L-fucopyranoside (2) were obtained. Apigenin6-C-(2"-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside (3) was isolated from the n-butanol fraction. Compound 3 is new, while 1 and 2 have been previously isolated from A. carambola. The antioxidant activity was measured using the DPPH ra...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Anti-schistosomiasis triterpene glycoside from the Egyptian medicinal plant Asparagus stipularisEmail this article to a colleague.
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Bioassay-guided isolation using an in vitro assay testing for anti- schistosomiasis yielded a novel triterpene saponin, asparagalin A, from the n-butanol extract of the roots of Asparagus stipularis Forssk., Asparagaceae. The structure was elucidated by spectroscopic analysis and chemical transformations. Administration of asparagalin A resulted in a retardation of worm growth and locomotion at the first day and showed a significant activity of egg-laying suppression at 200 µg/mL concentration. (Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Antiherpetic activity of a flavonoid fraction from Ocotea notata leavesEmail this article to a colleague.
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This study describes the isolation of a flavonoid fraction from leaves of Ocotea notata (Nees & Mart.) Mez, Lauraceae, the identification of six major compounds (an A-type proanthocyanidin trimer [3], isoquercitrin [4], reynoutrin [5], miquelianin [6], quercitrin [7], afzelin [8]) and four minor compounds (catechin [1], epicatechin [2], quercetin [9], kaempferol [10]) present in the fraction and its activity against the Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). The 50% effective concentrations values (EC50) calculated from the dose-response curve and the selectivity indices (SI) against the virus were: EC50 3...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Essential oil composition and isolation of freeradical-scavenging phenolic glycosides from the aerial parts of Ajuga chamaepitys growing in IranEmail this article to a colleague.
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From the methanolic extract of the aerial parts of Ajuga chamaepitys (L.) Schreb., Lamiaceae, one of the Iranian medicinal plants, the phenylethanoid glycoside, acteoside, and two flavone glycosides, chrysoeriol 7-O-glucopyranoside (3'-methoxy-luteolin 7-O-glucopyranoside) and apigenin 7-O-rhamnopyranoside, were isolated by a combination of solid-phase extraction (SPE) and preparative reversed-phase high-performance liquid chromatography (prep-RP-HPLC) methods. Structures of the isolated compounds were elucidated by spectroscopic means. The free-radical-scavenging properties of the extracts, fractions and isolated compound...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Chemical composition and antioxidant activity of lichen Toninia candidaEmail this article to a colleague.
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In the present investigation, methanol, chloroform and petrol ether extracts from the lichen Toninia candida (Weber) Th. Fr, Catillariaceae, were assayed for their antioxidant activity. The phenolic composition of the extracts was determined by HPLC-UV analysis. The predominant phenolic compound in all the extracts was depsidone, norstictic acid. All the tested extracts of T. candida contain, besides norstictic acid, atranorin, stictic, protocetraric and usnic acid, but in different amounts and relations. The lichen extracts showed comparable and strong antioxidant activity, exhibited higher DPPH and hydroxyl radical scave...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Physicochemical characteristics and antioxidant activity of melanoidin pigment from the fermented leaves of Orthosiphon stamineusEmail this article to a colleague.
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The melanoidin pigment (OS-M) was isolated from fermented leaves of Orthosiphon stamineus Benth. (Lamiaceae), with a 0.37% yield (from dry plant weight), and characterised. OS-M is a phenolic polymer with a molecular weight Keywords: of 4.4 kDa. Determination of basic physicochemical parameters using elemental antioxidant activity analysis, functional group analysis, UV-Vis-and FTIR-spectroscopy of OS-M fermented leaves indicated that the isolated polymer was similar to typical melanoidins. Experimental Lamiaceae data show that aromatic fragments dominate the OS-M structure, which also contains melanoidin a small amount of...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Composition and antimicrobial activities of the leaf essential oil of Machilus zuihoensis from TaiwanEmail this article to a colleague.
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This study investigated the chemical composition, and antimicrobial and anti-wood-decay fungal activities of the essential oil isolated from the leaf of endemic Machilus zuihoensis Hayata, Lauraceae, of Taiwan. The essential oil from the fresh leaves of M. zuihoensis was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. A total of 104 compounds were identified, representing 100% of the oil. The main components identified were n-dodecanal (23.8%) and (E)-nerolidol (10.5%). The antimicrobial activity of the oil was tested by the disc diffusion method and micro-broth diluti...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Wogonin and neobaicalein from Scutellaria litwinowii roots are apoptotic for HeLa cellsEmail this article to a colleague.
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Chemical investigation on the CH2Cl2 fraction of the Scutellaria litwinowii Bornm. & Sint., Lamiaceace, root extract for the first time resulted in the isolation of wogonin, and neobaicalein. These compounds were evaluated for their cytotoxicity towards HeLa cell lines and lymphocytes. Meanwhile, the role of apoptosis was explored in this toxicity. The cells were cultured in RPMI medium and incubated with different concentrations of isolated flavonoids. Cell viability was quantified by MTS assay. Apoptotic cells were determined using propidium iodide staining of DNA fragmentation by flow cytometry (sub-G1peak). Wogonin, an...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Evaluating methods for the isolation of marine-derived fungal strains and production of bioactive secondary metabolitesEmail this article to a colleague.
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In the present investigation we evaluate methods for the isolation and growth of marine-derived fungal strains in artificial media for the production of secondary metabolites. Inoculation of marine macroorganisms fragments in Petri dishes proved to be the most convenient procedure for the isolation of the largest number of strains. Among the growth media used, 3% malt extract showed the best result for strains isolation and growth, and yielded the largest number of strains from marine macroorganisms. The percentage of strains isolated using each of the growth media which yielded cytotoxic and/or antibiotic extracts was in ...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Centrolobium tomentosum: macro-and microscopic diagnosis of the leaf and stemEmail this article to a colleague.
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Centrolobium tomentosum Guillemin ex Benth., Fabaceae, known as "araribá-rosa", is a large tree that is widespread throughout Brazil. The bark of its stem is used in folk medicine as an astringent and the leaves are employed as a poultice for wounds and bruises. The aim of this study was to contribute to the pharmacognostic quality control of this medicinal species through a macro- and microscopic diagnosis of its leaves and stems. Mature leaves and young stems were collected at Embrapa (Colombo, PR) and analyzed using standard microtechniques. The leaves are opposite or alternate, compound, imparipinnate, oblong-lanceola...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Ethnobotanical, pharmacognostical, pharmacological and phytochemical studies on Smilax domingensis in GuatemalaEmail this article to a colleague.
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This article reports the taxonomic determination, cultivation of drug material, evaluation of use by in vitro and in vivo pharmacological assays, and phytochemical characterization. Extracts from cultivated material was evaluated by antimicrobial, anti-inflammatory, analgesic and immunomodulatory models, confirming the antimicrobial and immunomodulatory activities. Phytochemistry was done in the crude drug and extracts. Quality control parameters are described (micrographic drawings and phytochemical characteristics). Evidence is presented that cultivated rhizome has antimicrobial and immunomodulatory activities, validatin...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research
Zuclopenthixol: Various toxicities: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Zolpidem: Somnambulism in an elderly patient: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Zolpidem: Nocturnal sleep-related eating disorder: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Zoledronic acid: First report of cutaneous B-cell pseudolymphoma: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Paracetamol/venlafaxine overdose: Cardiomyopathy: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Warfarin: Purple toe syndrome: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Various drugs: Acute pancreatitis: 11 case reportsEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Ustekinumab: Cutaneous infarction: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Valproic acid: Eosinophilic pleural effusion: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Vancomycin: Linear IgA dermatosis in an elderly patient: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Valproic acid: Leucocytoclastic vasculitis: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Tretinoin: Scrotal ulcer: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Thiamazole: Agranulocytosis in an elderly patient: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Thiamazole: Aplasia cutis congenita and other anomalies following in utero exposure: 2 case reportsEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Tacrolimus: Dysarthria, leading to mutism: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Sildenafil: Nonarteritic anterior ischaemic optic neuropathy: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Sirolimus: Stent thrombosis associated with Kounis syndrome: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Rituximab: Myocardial infarction: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Rituximab: Interstitial pneumonitis: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
Risperidone: Neuroleptic malignant syndrome in a child: case reportEmail this article to a colleague.
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Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research
