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Ghost-writing used to promote Paxil 1 Comment
Source: Pharmacy Europe Category: Drugs & Pharmacology
Latest Comment by Hunter Flowers - August 21, 2009: It's no news that giants like GSK are using and abusing some black-hat techniques, otherwise there wouldn't be nearly the suffering and death that there are in the world.

Levofloxacin: Hypoglycaemia leading to myelinolysis (first report) and quadriplegia (first report) in a patient with type 2 diabetes: case report 1 Comment
Source: Reactions Category: Drugs & Pharmacology
Latest Comment by WhataBreeze - July 21, 2009: I acquired Central Pontine Myelinolysis in 2002. Since then I have been doing research on this sad disease/disorder that has been termed an iatrogenic (error in physicians treatment) event. All you hear is 1,000,s of issues in regard to alcohol and/or hyponatremia. Some of these clinicians should try living with CPM for a while prior to writing their "VISIONS," as I'm sure it will help give the public some reality. I personally have started a Foundation on my own from my home. I'm not registered as an org. as of yet but I also have not allowed small young children to go without being evaluated as I was. My personal tr...

Key Elements of Bioanalytical Method Validation for Macromolecules 1 Comment
Source: The AAPS Journal Category: Drugs & Pharmacology
Latest Comment by Andre - July 15, 2009: I have issues with the statement: "Standard points outside of the range of quantification (anchor calibrators) are often used to assist in fitting these nonlinear regression models". I agree that anchor points are very helpful in assisting curve fitting, but without defining set rules on how to decide whether they are actually improving the curve, I fear that anchor point rejection remains too subjective. I have read in many places that anchor points should not have the precision & accuracy acceptance criteria used for non-anchor points; I agree, but then what criteria should we use? Some type of sum of squares calculation...

Evaluation of wound healing potential of Chicorium intybus in rats as animal model 1 Comment
Source: Iranian Journal of Pharmacology & Therapeutics (IJPT) Category: Drugs & Pharmacology
Latest Comment by navpreet - March 10, 2009: hello sir, i m doing project in masters of pharmacy(pharmacgnosy).my project is pharmacognostic and phytochemical investigation of roots and leaves of chicorium intybus.can u tell me the procedure u done for wound heeling property? or any suggestion regarding my work

Formulation and evaluation of flurbiprofen microemulsion. 1 Comment
Source: Current Drug Delivery Category: Drugs & Pharmacology
Latest Comment by sushil - February 18, 2009: can we make SEDDS of flurbiprofen? Is it justify?

Modafinil gets a reaction in Australia; ten, actually 1 Comment
Source: Inpharma Category: Drugs & Pharmacology
Latest Comment by BruceAlan - February 14, 2009: So, we have 10 documented delayed-type hypersensitivity "reactions" to Provigil within a short while in Australia. Meanwhile, no cases at all of delayed-type hypersensitivity were reported by the FDA until the very beginning of 2008. That was when, as if by epidemic, 6 similar cases suddenly appeared in the US. That would mean that we are expected to believe that for a full 9 years - NINE YEARS! - following its release by Cephalon after FDA approval in 1998, no cases emerged post-approval due to use of Provigil in the States - a country with 12 times the population of Australia. Yet the FDA's own records reveal th...

Detecting signals of opioid analgesic abuse: application of a spatial mixed effect poisson regression model using data from a network of poison control centers 1 Comment
Source: Pharmacoepidemiology and Drug Safety Category: Drugs & Pharmacology
Latest Comment by Marianne Skolek - January 24, 2009: You should know what I know about Purdue Pharma and OxyContin. I know that in April 2002, I lost my beautiful 29 year old daughter Jill to prescribed OxyContin. I know I worked tirelessly from 2002 until today, to expose Purdue Pharma for criminally marketing OxyContin. I know that in July 2007, I was asked by U.S. Attorney Brownlee of Virginia to make an impact statement in Federal Court at the sentencing of Purdue Pharma's three CEO's Michael Friedman, Howard Udell and Paul Goldenheim for convincing physicians and patients that OxyContin was less likely to be addictive or abused. I know in my statement I called them ...

Anti-diabetic, anti-hyperlipidemic and spermatogenic effects of Amaranthus spinosus Linn. on streptozotocin-induced diabetic rats 1 Comment
Source: Journal of Natural Medicines Category: Drugs & Pharmacology
Latest Comment by s.s.somanathan - December 12, 2008: good day sir. it's excellent. i need PDF of this article soon.

Cefuroxime axetil: Kounis syndrome in an elderly patient: case report 1 Comment
Source: Reactions Category: Drugs & Pharmacology
Latest Comment by Toula Soufra - December 2, 2008: Kounis syndrome seems to be not a rare disease but a very rarely diagnosed disease!

Preparation and Evaluation of Chitosan/Carrageenan Beads for Controlled Release of Sodium Diclofenac 1 Comment
Source: AAPS PharmSciTech Category: Drugs & Pharmacology
Latest Comment by Ms.Dipali Dhoke - November 14, 2008: can I use the drug ACECLOFENAC for preparing such types of beads by using diffrent polymer combination.

Might statins be associated with increased risk of ALS? 3 Comments
Source: NeLM Headline News Category: Drugs & Pharmacology
Latest Comment by kevin.price20@ntlworld.com - November 12, 2008: My Mum of 67 has MND, SHE IS CONVINCED IT HAS BEEN CAUSED BY STATINS. My Mum has been taking a high dose of 80mg for over 6 mths and started to notice spasams in her legs within six mounths.After a year and many disagreemets with her GP she came off all tablets only o find she has MND.Can anyone tell me if the two are linked?

Recent challenges in insulin delivery systems: A review 1 Comment
Source: Indian Journal of Pharmaceutical Sciences Category: Drugs & Pharmacology
Latest Comment by Dan - September 24, 2008: The Pumpers: Better compliance for Insulin-dependent diabetic patients? With some diabetic patients, the hormone insulin may be absent, yet necessary for their survival. As I recall, a man named Pauescu developed the concept of insulin replacement, and discovered a method of using insulin secreted from pigs as a replacement method for humans, which was effective at that time. Legend has it that this concept originated in a dream this man had on a night soon before his idea became reality several decades ago. Yet presently, this hormone which is naturally produced by the pancreas normally has advanced as far as treat...

Measles, mumps and rubella virus vaccine: Epididymo-orchitis: case report 1 Comment
Source: Reactions Category: Drugs & Pharmacology
Latest Comment by anacleta05 - September 9, 2008: this website is really a good help for me specially when im searching for different diseases.

GSK issues “Dear Healthcare Professional” letter warning of risk of oral clefts with lamotrigine use in early pregnancy 1 Comment
Source: NeLM Headline News Category: Drugs & Pharmacology
Latest Comment by smile - August 30, 2008: I took lamictal when I was pregnant only because my dr prescribed it and my baby was born with a bilateral cleft lip and palate. Does anyone have any legal suggestions

Age and gender effects evident in hypertension treatment. 1 Comment
Source: Inpharma Weekly Category: Drugs & Pharmacology
Latest Comment by jerica - May 3, 2008: gud

Chief Dental Officer issues letter in response to NICE Guidance on antibiotic prophylaxis against infective endocarditis 1 Comment
Source: NeLM Headline News Category: Drugs & Pharmacology
Latest Comment by Dr David Shanson - April 23, 2008: The risk of fatal anaphylaxis after amoxicillin has probably been overestimated and there is a lack of good data on amoxicillin compared with anaphylaxis after penicillin or ampicillin.A survey in the UK showed no evidence of reports of fatal anaphylaxis after amoxicillin prophylaxis of endocarditis : Lee P and Shanson D Results of a UK survey of fatal anaphylaxis after oral amoxicillin J Antimicrob Chemother 2007; 60: 1172-1173 The American Heart Association(AHA) 2007 guidelines aso stated amoxicillin is a safe drug without reports of fatal anaphylaxis associated with the prophylaxis of endocarditis. The cost effectiv...

An alternative therapy for graves' disease. 1 Comment
Source: Biological and Pharmaceutical Bulletin Category: Drugs & Pharmacology
Latest Comment by GayE - April 21, 2008: This is very interesting BUT I can't find any references for Ahnjeonbaekho-tang. So cannot compare without side effects, availability, administration, etc details.

Might statins be associated with increased risk of ALS? 3 Comments
Source: NeLM Headline News Category: Drugs & Pharmacology
Latest Comment by Frankie Dolan - March 14, 2008: Sorry to hear about your sad loss David. Thank-you for sharing this information.

Might statins be associated with increased risk of ALS? 3 Comments
Source: NeLM Headline News Category: Drugs & Pharmacology
Latest Comment by David McM, Glasgow - March 14, 2008: My wife Pauline McMurtrie [aged 74] who died six weeks ago from effects of MND - diagnosed in Glasgow in December, 2005, by Dr Richard Petty, Southern General, Glasgow, and confirmed in London by Prof. Nigel Leigh, at King's College Hospital - firmly contended her use of statins [after heart attack] from 1995 to 2004 contributed to the onset of MND. It began with muscle spasms and cramps in legs, which reduced and almost ceased when statins were withdrawn. No medical opinion confirmed she was correct in her suspicions, with the answer being this was unlikely. Her worry, and mine, if this is not the case is that the MND co...