Drugs & Pharmacology Top 20
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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.
Arthritis "healing" advert banned
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An advert claiming that a special patch can help to heal arthritis, back pain, sciatica and fibromyalgia has been banned by the advertising watchdog (Source: Pharmacy Europe)
Source: Pharmacy Europe - November 18, 2009 Category: Drugs & Pharmacology Source Type: news
Swine flu may increase MRSA cases
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An increasing number of swine flu patients being treated in hospitals may lead to a rise in cases of MRSA (Source: Pharmacy Europe)
Source: Pharmacy Europe - October 21, 2009 Category: Drugs & Pharmacology Source Type: news
MHRA extends ADR reporting programme for H1N1 (swine flu) antivirals to include vaccines
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Source: MHRA
Area: News
The MHRA has extended its dedicated Adverse Drug Reaction (ADR) website for reporting suspected side effects to H1N1 (swine flu) antivirals to now include separate reports about the recently introduced vaccines. A dedicated team of drug safety scientists are responsible for reviewing ADR reports submitted to the Agency through the Swine Flu Portal allowing fast, real-time surveillance of possible side effects. (Source: NeLM - News)
Source: NeLM - News - October 22, 2009 Category: Drugs & Pharmacology Source Type: organizations
Tysabri alert over brain infection
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Labelling of multiple sclerosis drug has been changed to point up the increased risk of contracting multifocal leukoencephalopathy (Source: Pharmacy Europe)
Source: Pharmacy Europe - November 9, 2009 Category: Drugs & Pharmacology Source Type: news
MHRA announce safety monitoring programme for swine flu vaccines
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(Source: Reactions)
Source: Reactions - October 31, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
Novartis receives regulatory approval in Germany for Celtura
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Approval of Celtura marks an important milestone in the process of replacing 50 year-old egg-based flu vaccine production with modern biotechnology (Source: Pharmacy Europe)
Source: Pharmacy Europe - November 5, 2009 Category: Drugs & Pharmacology Source Type: news
Swine flu guidance for planners (October 2009)
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Source: Department of Health (DH)
Area: News
The Department of Health and the Cabinet Office have published new guidance to support pandemic planners based on the latest science and understanding of the swine flu virus. The latest evidence indicates that the pandemic may peak at a lower rate than originally thought, but does not suggest that there should be any change to response in terms of ensuring the NHS and social care organisations are as prepared and resilient as possible for the winter months. The National Director for NHS Flu Resilience, and the Director General, NHS Finance, Performance and Operations, have writ...
Source: NeLM - News - October 22, 2009 Category: Drugs & Pharmacology Source Type: organizations
Creation Of New Transatlantic Task Force On Global Antibiotic Resistance Threat Applauded By U.S. And European Experts
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Experts on both sides of the Atlantic applaud President Barack Obama and Swedish Prime Minister Fredrik Reinfeldt, representing the European Union (EU) Presidency, for establishing a transatlantic task force to address antibiotic resistance, an urgent and growing problem that threatens patient safety and public health worldwide. During a summit held this week in Washington, D.C. (Source: MRSA / Drug Resistance News From Medical News Today)
Source: MRSA / Drug Resistance News From Medical News Today - November 9, 2009 Category: Drugs & Pharmacology Tags: MRSA / Drug Resistance Source Type: news
New Three-Year Grant From The Bill & Melinda Gates Foundation Announced By Keystone Symposia
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Keystone Symposia on Molecular and Cellular Biology is pleased to announce that it has received a second grant from the Bill & Melinda Gates Foundation to fund conferences on infectious disease in its "Keystone Symposia Global Health Series." In 2006, the Colorado, USA-based nonprofit organization received its first three-year grant; the funding for that ended with the October 20-25, 2009 conference on "Overcoming the Crisis of TB and AIDS" in Arusha, Tanzania. The new grant provides $2. (Source: MRSA / Drug Resistance News From Medical News Today)
Source: MRSA / Drug Resistance News From Medical News Today - November 9, 2009 Category: Drugs & Pharmacology Tags: HIV / AIDS Source Type: news
Improving Follow-Up Rates in Spontaneous Adverse Drug Reaction Reporting: Effectiveness of a Targeted Letter Used by a Regional Centre in the UK
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(Source: Drug Safety)
Source: Drug Safety - November 18, 2009 Category: Drugs & Pharmacology Authors: Anton, ChristopherCox, Anthony R.Ferner, Robin E. Tags: Short Communications Source Type: journals
What information is NHS Direct giving patients about swine flu vaccination? - updated November 2009
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Source: London Medicines Information Service
Area: Evidence > Medicines Q & A
NHS Direct Medicines Fact Sheet - Swine flu vaccine
At the time of writing, three swine flu vaccines have been approved for use by the European Medicines Agency - Pandemrix® (GSK), Celvapan® (Baxter) and Focetria® (Novarits; not available in the UK). This fact sheet contains the following information about the vaccines:
. General information . Indications . Contraindications . Warnings and cautions . Dose and administration . Common adverse effects . Rare adverse effects . Time to eff...
Source: NeLM - Medicines Q & A - November 9, 2009 Category: Drugs & Pharmacology Source Type: organizations
HPA weekly pandemic flu update 22 October 2009
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Source: Health Protection Agency
Area: News
The latest pandemic flu update from the HPA for the week ending 22 October 2009 includes the following data:
. Flu-like illness rate in England from the RCGP scheme increased to 39.1 per 100,000 in week 42 compared to 29.1 in week 41; an increase was seen in all age groups.
. The main burden of flu-like illness nationally is in the 1 to 4 and 5 to 14 years age groups.
. This week, the antiviral collection numbers in the National Pandemic Flu Service have continued to increase and this has been seen in all age groups except the 75+....
Source: NeLM - News - October 22, 2009 Category: Drugs & Pharmacology Source Type: organizations
Why Certain Drug Combinations Backfire
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Combination drug therapy has become a staple for treating many infections. For instance, doctors treat extensively drug resistant forms of tuberculosis with one drug that breaks down the pathogen's protective barriers and opens the door for another to deliver the deathblow. Just as some drugs work better together, however, other pairings are counter-productive. (Source: MRSA / Drug Resistance News From Medical News Today)
Source: MRSA / Drug Resistance News From Medical News Today - November 16, 2009 Category: Drugs & Pharmacology Tags: MRSA / Drug Resistance Source Type: news
New Chemical May Play Key Role In Hospital Superbugs' Battle, UK
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A new chemical compound that mimics the body's ability to fight bacteria could help target hospital-acquired infections such as MRSA and C.difficile. The compound, which could be added to detergents or used as a coating for hospital equipment, is able to trap and release the gas nitric oxide - which is also produced by our own immune systems to kill bugs. (Source: MRSA / Drug Resistance News From Medical News Today)
Source: MRSA / Drug Resistance News From Medical News Today - November 20, 2009 Category: Drugs & Pharmacology Tags: MRSA / Drug Resistance Source Type: news
NSAID switching and short-term gastrointestinal outcome rates after the withdrawal of rofecoxib
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The consequences of the rofecoxib withdrawal on upper GI toxicity are largely unknown. We sought to estimate the effect of switching from selective Cox-2 inhibitors to non-selective non-steroidal anti-inflammatory drugs (nsNSAIDs) on the incidence of upper GI adverse events following the withdrawal of rofecoxib on 30 September 2004.We identified a cohort of 33 045 patients with arthritis and chronic use of any selective Cox-2 inhibitor during the 6 months before the withdrawal of rofecoxib in claims data from several US health plans. We calculated monthly rates of hospitalization for upper GI adverse events or upper GI end...
Source: Pharmacoepidemiology and Drug Safety - October 20, 2009 Category: Drugs & Pharmacology Authors: Sebastian Schneeweiss, Robert J. Glynn, Jerry Avorn, Muhammad Mamdani, Helen Mogun, Daniel H. Solomon Source Type: journals
'Clever Cleaning' The Way To Beat Hospital Superbugs, UK
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Just one extra cleaner on a hospital ward can save lives and money, according to new research sponsored by UNISON, the UK's largest public service union. The detailed study found that one extra cleaner, using targeted cleaning methods, had a "measurable effect on the clinical environment," cutting the number of patients who contracted MRSA and saving the hospital an estimated £30,000 - £70,000. (Source: MRSA / Drug Resistance News From Medical News Today)
Source: MRSA / Drug Resistance News From Medical News Today - November 6, 2009 Category: Drugs & Pharmacology Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Synthesis and Antistaphylococcal Activity of N-Substituted-1H-benzimidazole-sulphonamides
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A series of N-substituted-1H-benzimidazole-5(6)-sulfonamides and 3-(5,6-dichloro-1H-benzimidazol-2-yl)-N-substituted benzensulfonamides were synthesized and evaluated for antibacterial activity against Staphylococcus aureus and methicillin-resistant S. aureus (MRSA). Certain compounds inhibit bacterial growth with low MIC ([mu]g/mL) values. The most active compounds 30, 31, and 32 have the lowest MIC values with 0.39 to 0.19 [mu]g/mL. Among the compounds having sulfonamido moities, 16, 23, and 24 exhibited the strongest antibacterial activity with 1.56 [mu]g/mL MIC values. (Source: Archiv der Pharmazie)
Source: Archiv der Pharmazie - November 20, 2009 Category: Drugs & Pharmacology Authors: M. Orhan Püsküllü, Sulhiye Y[inodot]ld[inodot]z, Hakan Göker Source Type: journals
Cytarabine: MRSA pyomyositis: case report
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(Source: Reactions)
Source: Reactions - November 11, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
The benzoxathiolone LYR-71 down-regulates interferon-γ-inducible pro-inflammatory genes by uncoupling tyrosine phosphorylation of STAT-1 in macrophages
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Conclusions and implications: Taken together, LYR-71 could restrain IFN-[gamma]-induced inflammatory responses through uncoupling the tyrosine phosphorylation of STAT-1, an activation index of JAK[ndash]STAT-1 signalling, in macrophages. These results may provide a molecular mechanism underlying anti-inflammatory actions shown by benzoxathiolone derivatives. (Source: British Journal of Pharmacology)
Source: British Journal of Pharmacology - November 18, 2009 Category: Drugs & Pharmacology Authors: E-Y Chung, B-H Kim, I-J Lee, E Roh, S-J Oh, J-A Kwak, Y-R Lee, B Ahn, S-Y Nam, S-B Han, Y Kim Source Type: journals
Certain lots of Tylenol [paracetamol, acetaminophen] Arthritis Pain Caplets are being voluntarily recalled in the US.
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(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals
