Editorial
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(Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - July 5, 2008 Category: Drugs & Pharmacology Source Type: journals
Actions of the ashp board of directors-- meeting of june 23 and june 26, 2007.
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Actions of the ASHP Board of Directors-- Meeting of June 23 and June 26, 2007.
Am J Health Syst Pharm. 2008 Jul 15;65(14):e18
Authors:
PMID: 18593672 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Tags: Am J Health Syst Pharm Source Type: journals
Health care worker vaccination takes stage as flu season approaches.
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PMID: 18593673 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Traynor K Tags: Am J Health Syst Pharm Source Type: journals
Pharmacists run telehealth clinic to keep veterans independent.
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PMID: 18593674 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Thompson CA Tags: Am J Health Syst Pharm Source Type: journals
Pharmacy schools help educate, treat appalachian patients at virginia health fair.
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Pharmacy schools help educate, treat Appalachian patients at Virginia health fair.
Am J Health Syst Pharm. 2008 Jul 15;65(14):1311-3
Authors: Lavine G
PMID: 18593675 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Lavine G Tags: Am J Health Syst Pharm Source Type: journals
Introduction to pediatric pharmacy practice: reflections of pediatrics practitioners.
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PMID: 18593676 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Pesaturo KA, Ramsey EZ, Johnson PN, Taylor LM Tags: Am J Health Syst Pharm Source Type: journals
Aliskiren: will a novel mechanism improve clinical outcomes?
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PMID: 18593677 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Roffman DS Tags: Am J Health Syst Pharm Source Type: journals
Aliskiren.
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CONCLUSION: Aliskiren at a dosage of 150 or 300 mg daily may be a good option for control of mild-to-moderate hypertension in patients with or without diabetes in whom first-line antihypertensives have failed to adequately control BP; comparative studies with other antihypertensives are needed to determine which patients can most benefit from aliskiren therapy.
PMID: 18593678 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Daugherty KK Tags: Am J Health Syst Pharm Source Type: journals
Paclitaxel-induced sickle cell crisis.
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CONCLUSION: A patient with breast cancer and SCD had a painful crisis after receiving paclitaxel as part of her chemotherapy regimen.
PMID: 18593679 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Wilson NM, Espirito JL, Valero V, Pusztai L Tags: Am J Health Syst Pharm Source Type: journals
Optimizing transdermal drug therapy.
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CONCLUSION: The increasing complexity of transdermal drug products, the growing number of medications available in such dosage forms, and reports of potential safety concerns contribute to the need for clinicians to understand the principles of transdermal drug delivery, safe usage techniques, and proper patient counseling points.
PMID: 18593680 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Ball AM, Smith KM Tags: Am J Health Syst Pharm Source Type: journals
Patient satisfaction and costs associated with insulin administered by pen device or syringe during hospitalization.
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CONCLUSION: Increased patient satisfaction and continuation of the method of insulin administration used in the hospital at home were reported by patients who received insulin pens compared with patients who received conventional vials and syringes during hospitalization. A substantial cost saving was projected for patients in the insulin pen group if insulin pens had been dispensed during their entire hospital stay.
PMID: 18593681 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Davis EM, Christensen CM, Nystrom KK, Foral PA, Destache C Tags: Am J Health Syst Pharm Source Type: journals
Effect of a seminar on pharmacy student attitudes toward residency training.
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CONCLUSION: A mandatory one-hour seminar on residencies did not influence pharmacy students' opinions of and plans for residency training, but it did identify factors affecting their decisions.
PMID: 18593682 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Jacobs TF, Manor SM Tags: Am J Health Syst Pharm Source Type: journals
Formulary decisions for pre-1938 medications.
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CONCLUSION: A systematic approach to reviewing pre-1938 medications for the purpose of formulary revision was successful in addressing safety concerns about these older drug formulations.
PMID: 18593683 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Authors: Culley CM, Carroll BA, Skledar SJ Tags: Am J Health Syst Pharm Source Type: journals
Ashp guidelines on medication cost management strategies for hospitals and health systems.
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ASHP guidelines on medication cost management strategies for hospitals and health systems.
Am J Health Syst Pharm. 2008 Jul 15;65(14):1368-84
Authors:
PMID: 18593684 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - July 5, 2008 Category: Drugs & Pharmacology Tags: Am J Health Syst Pharm Source Type: journals
Gene could help in cancer fight
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Gene found to cause apoptosis in cancer without harming healthy cells (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 5, 2008 Category: Drugs & Pharmacology Source Type: news
Us approval for hpv vaccine delayed
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GSK to await results of trial before seeking approval from the FDA (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 5, 2008 Category: Drugs & Pharmacology Source Type: news
High court to rule on sutent access
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UK cancer patient takes battle to High Court after local health trust denies her sunitinib (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 5, 2008 Category: Drugs & Pharmacology Source Type: news
European approval for relistor
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EMEA approve targeted treatment for opioid-induced constipation (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 5, 2008 Category: Drugs & Pharmacology Source Type: news
Pharma worst for employee misunderstanding
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UK pharmaceutical staff misunderstanding costs the sector EUR 29.8m every year (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 5, 2008 Category: Drugs & Pharmacology Source Type: news
Atrial fibrillation due to late amiodarone-induced thyrotoxicosis
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Ibrahim Halil Kurt,Yigit, TalatBulent Mustafa Karademir, Tags: Case Report Source Type: journals
Development of vitreous haemorrhage during treatment with bevacizumab for metastatic rectal cancer
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Huang, Gwo-CheChen, Lee-JenLiu, Hung-ChangChen, Yu-Jen Tags: Case Report Source Type: journals
Voriconazole treatment of invasive aspergillosis: real-world versus health-economic model results
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Hilde Van Campenhout,Marbaix, SophieDerde, Marie-PauleAnnemans, Lieven Tags: Original Research Article Source Type: journals
Relationship between haemoglobin a1c values and recurrent cardiac events: a retrospective, longitudinal cohort study
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Kauffman, Amy B.Delate, ThomasOlson, Kari L.Cymbala, Alicia A.Hutka, Kara A.Kasten, Sheila L.Rasmussen, Jon R. Tags: Original Research Article Source Type: journals
Thioctic acid and acetyl-l-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Memeo, AntonioLoiero, Mario Tags: Original Research Article Source Type: journals
Haemoglobin a1c goal attainment in relation to dose in patients with diabetes mellitus taking metformin: a nested, case-control study
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Beest, Fernie J.A. Penning-vanWolffenbuttel, Bruce H.R.Herings, Ron M.C. Tags: Original Research Article Source Type: journals
Effect of repeated doses of darunavir plus low-dose ritonavir on the pharmacokinetics of sildenafil in healthy male subjects: phase i randomized, open-label, two-way crossover study
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Sekar, V.Lefebvre, E.De Marez, T.De Pauw, M.De Paepe, E.Vangeneugden, T.Hoetelmans, R.M.W. Tags: Original Research Article Source Type: journals
Practical issues with amisulpride in the management of patients with schizophrenia
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(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - July 5, 2008 Category: Drugs & Pharmacology Authors: Pani, LucaVillagran, Jose M.Kontaxakis, Vassilis P.Alptekin, Koksal Tags: Review Article Source Type: journals
Coexistent primary open-angle glaucoma and cataract: preliminary analysis of treatment by cataract surgery and the istent trabecular micro-bypass stent.
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CONCLUSION: In this interim analysis of subjects with glaucoma and cataracts, this novel stent implantation in subjects undergoing cataract surgery represents a new surgical approach to provide clinically significant decreases in IOP and drug burden.
PMID: 18594784 [PubMed - in process] (Source: Advances in Therapy)
Source: Advances in Therapy - July 4, 2008 Category: Drugs & Pharmacology Authors: Spiegel D, García-Feijoó J, García-Sánchez J, Lamielle H Tags: Adv Ther Source Type: journals
Us urges diabetes drug slowdown
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FDA panel says more stringent safety checks are needed for new diabetes treatments (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 4, 2008 Category: Drugs & Pharmacology Source Type: news
Ec present cross-border care proposal
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The European Commission adopts proposed directive for patients' rights in cross-border healthcare (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 4, 2008 Category: Drugs & Pharmacology Source Type: news
Mrsa increases risk of infection
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Study shows MRSA patients have a raised risk of serious subsequent infection (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 4, 2008 Category: Drugs & Pharmacology Source Type: news
Albert hofmann (1906 – 2008) – an obituary
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Planta Med 2008; 74: 791-793DOI: 10.1055/s-2008-1081289© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Full text (Source: Planta Medica)
Source: Planta Medica - July 4, 2008 Category: Drugs & Pharmacology Tags: Editorial Source Type: journals
Triterpenes from
cynomorium songaricium
—analysis of hcv protease inhibitory activity, quantification, and content change under the influence of heating
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Abstract Inhibitory activity of the three major triterpenes from the stems of Cynomorium songaricum—ursolic acid, acetyl ursolic acid, and malonyl ursolic acid hemiester—and their related compounds were tested for their inhibitory
activity on HCV protease; malonyl ursolic acid hemiester was the most potent. A HPLC–PAD (photo diode array detector)–MS method
was established to quantify the contents of each triterpene in C. songaricum. Using this method, the effect heating had on the contents was also investigated. It was found that among the three triterpenes,
the content of malonyl ursolic acid hemiest...
Source: Journal of Natural Medicines - July 4, 2008 Category: Drugs & Pharmacology Tags: Journal of Natural Medicines Source Type: journals
Lignan and flavonoid glycosides from
urtica laetevirens
maxim.
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Abstract A new compound named pinoresinol 4-O-α-l-rhamnopyranosyl (1 → 2)-β-d-glucopyranoside (1) together with six known compounds, isolariciresinol 9-O-β-D-glucopyranoside (2), apigenin 6,8-di-C-β-d-glucopyranoside (3), luteolin 7-O-neohesperidoside (4), luteolin 7-O-β-d-glucopyranoside (5), 5-methoxyluteolin 7-O-β-d-glucopyranoside (6), and rutin (7), were isolated from the aerial parts of Urtica laetevirens Maxim. All of the above compounds were isolated from this plant for the first time.
Content Type Journal ArticleCategory Natural Medicine NoteDOI 10.1007/s11418-008-0274-8Authors
Yu...
Source: Journal of Natural Medicines - July 4, 2008 Category: Drugs & Pharmacology Tags: Journal of Natural Medicines Source Type: journals
Optimal modeling for phase i design of a two drug combination—results of a phase i study of cisplatin with 9-nitrocamptothecin
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The objectives of this study were to determine MTD
range and toxicity profile of combinations of oral 9-nitrocamptothecin (9NC) and intravenous cisplatin in patients with refractory
solid tumors. Each course was 28 days starting on day 1 with cisplatin, and then 9NC daily for 5 days/week for three weeks.
A new two arm crossing design was created: patients in arm 1 were treated with at the single agent recommended dose of cisplatin
(50 mg/m2), and increasing doses of 9NC and in arm 2 with the single agent recommended dose of 9NC (1.5 mg/day) and increasing dose
of cisplatin. Once a dose limiting tox...
Source: Investigational New Drugs - July 4, 2008 Category: Drugs & Pharmacology Tags: Investigational New Drugs Source Type: journals
Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration
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Abstract
Aim The aim of the present study was to investigate the existence of time-dependent pharmacokinetics of artesunate (ARS) during
5 consecutive days of oral administration to 10 healthy Vietnamese subjects (aged 21–52 years and weighing 49–90 kg).
Methods Each volunteer received 200 mg oral doses of ARS once daily for 5 consecutive days. Blood samples (3 ml each) were collected
on days 1 and 5 at 0 (before dosing), 0.5, 1, 2, 3, 4, and 6 h after drug administration. During days 2, 3, and 4, the same
volumes of blood were collected at 0, 1, 2, an...
Source: European Journal of Clinical Pharmacology - July 4, 2008 Category: Drugs & Pharmacology Tags: European Journal of Clinical Pharmacology Source Type: journals
Roles of trp channels in the development of cardiac hypertrophy
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Abstract Cardiac hypertrophy is induced by various stresses such as hypertension and myocardial infarction. It is believed that hypertrophy
is adaptive in the early phase but becomes maladaptive in the late phase. Cardiac hypertrophy develops heart failure when
the heart is exposed persistently to the stresses. The increase in intracellular Ca2+ ([Ca2+]i) plays an important role in the development of hypertrophy. It is generally thought that the increase in [Ca2+]i for hypertrophy occurs via Gq-stimulated production of inositol-1,4,5-trisphosphate (IP3) and IP3-mediated release of Ca2+ from intracellular store...
Source: Naunyn-Schmiedeberg's Archives of Pharmacology - July 4, 2008 Category: Drugs & Pharmacology Tags: Naunyn-Schmiedeberg's Archives of Pharmacology Source Type: journals
Bioavailability enhancement and targeting of stomach tumors using gastro-retentive floating drug delivery system of curcumin-"a technical note"
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Bioavailability Enhancement and Targeting of Stomach Tumors Using Gastro-Retentive Floating Drug Delivery System of Curcumin-"A Technical Note"
AAPS PharmSciTech. 2008 Jul 4;
Authors: Shishu , Gupta N, Aggarwal N
PMID: 18600460 [PubMed - as supplied by publisher] (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - July 4, 2008 Category: Drugs & Pharmacology Authors: Shishu , Gupta N, Aggarwal N Tags: AAPS PharmSciTech Source Type: journals
Lignan and flavonoid glycosides from urtica laetevirens maxim.
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Lignan and flavonoid glycosides from Urtica laetevirens Maxim.
Nat Med (Tokyo). 2008 Jul 4;
Authors: Zhou Y, Wang W, Tang L, Yan XG, Shi LY, Wang YQ, Feng BM
A new compound named pinoresinol 4-O-alpha-L: -rhamnopyranosyl (1 --> 2)-beta-D: -glucopyranoside (1) together with six known compounds, isolariciresinol 9-O-beta-D-glucopyranoside (2), apigenin 6,8-di-C-beta-D: -glucopyranoside (3), luteolin 7-O-neohesperidoside (4), luteolin 7-O-beta-D: -glucopyranoside (5), 5-methoxyluteolin 7-O-beta-D: -glucopyranoside (6), and rutin (7), were isolated from the aerial parts of Urtica laetevirens Maxim. All of the ab...
Source: Natural Medicines - July 4, 2008 Category: Drugs & Pharmacology Authors: Zhou Y, Wang W, Tang L, Yan XG, Shi LY, Wang YQ, Feng BM Tags: Nat Med (Tokyo) Source Type: journals
Triterpenes from cynomorium songaricium-analysis of hcv protease inhibitory activity, quantification, and content change under the influence of heating.
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Triterpenes from Cynomorium songaricium-analysis of HCV protease inhibitory activity, quantification, and content change under the influence of heating.
Nat Med (Tokyo). 2008 Jul 4;
Authors: Ma CM, Wei Y, Wang ZG, Hattori M
Inhibitory activity of the three major triterpenes from the stems of Cynomorium songaricum-ursolic acid, acetyl ursolic acid, and malonyl ursolic acid hemiester-and their related compounds were tested for their inhibitory activity on HCV protease; malonyl ursolic acid hemiester was the most potent. A HPLC-PAD (photo diode array detector)-MS method was established to quantify the contents of ...
Source: Natural Medicines - July 4, 2008 Category: Drugs & Pharmacology Authors: Ma CM, Wei Y, Wang ZG, Hattori M Tags: Nat Med (Tokyo) Source Type: journals
Who benefits from antihypertensive therapies? ash meeting offers clues
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Here are highlights from the most recent ASH meeting. (Source: Drug Topics - Drug Information)
Source: Drug Topics - Drug Information - July 4, 2008 Category: Drugs & Pharmacology Source Type: news
Practice pointer: consultations for people from minority groups
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This article provides practical suggestions on ways to improve communication with people from minority ethnic and faith groups; the following subjects are discussed:
• Challenges to delivering culturally competent and sensitive care
• Summary of the evidence for interventions
• Strategies and approaches to enhancing delivery of care
• Responding to diversity in the consultation (Source: NeLM Headline News)
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: National Health Service Source Type: organizations
Review: new drug developments for crohn’s disease
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In this review on future directions in the management of Crohn’s disease, the authors review mechanisms of actions of new drugs and their efficacy and safety from clinical trial data. The pathways discussed include:
• T-cell blockade
• Blockade of T-cell differentiation or activation
• Resetting T-cells, Anti TNF strategies
• Regulatory T-cell modulation
• Blocking cell recruitment
• Enhancing repair
• Innate immune stimulation
• Induction of oral tolerance (Source: NeLM Headline News)
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: 1.5 Chronic bowel disorders, Inflammatory bowel disease, Drug reviews, New drugs Source Type: organizations
Seminar acute aortic dissection
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In this seminar, the authors discuss advances in the epidemiology, presentation, pathogenesis, diagnosis, and management of acute aortic dissection. In terms of drug treatment, they note that on the basis of data from patients with Marfan's syndrome, long-term beta blockade is usually recommended in patients with aortic dissection to maintain BP less than 130/80 mmHg. They add that pathways blocking angiotensin II may help to prevent aortic dissection and clinical trials investigating this are underway. (Source: NeLM Headline News)
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: 2.4 Beta-adrenoceptor blocking drugs, 2.5.5 Drugs affecting the renin-angiotensin system, Cardiac Surgery Source Type: organizations
Bmj analysis of nhs at 60: recent reforms and threat to founding principles
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In the final article in the BMJ series on the NHS at 60, the author looks at the effects of recent reforms and assesses the threat to its founding principles. He concludes “the most thoughtful birthday present the NHS could receive would be an assurance that after implementation of the Darzi inspired reforms there will be an extended period of calm before the next round of reforms is unleashed.” (Source: NeLM Headline News)
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: National Health Service Source Type: organizations
Uk surveillance data on imported malaria and high risk groups
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A study by the Health Protection Agency’s (HPA) Malaria Reference Laboratory published in the BMJ shows that “despite highly effective measures available to prevent malaria, the burden of disease among UK travellers has steadily increased over the last 20 years.”
The observational study used prospectively gathered surveillance data and data on destinations from the international passenger survey and reported the following findings:
• There were 39,300 cases of proved malaria in the UK between 1987 and 2006; 20,488 of these were in UK travellers and the remainder were visitors to the UK.
• Reported cases of imp...
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: 5.4.1 Antimalarials, Malaria, General Advice, Health Protection Agency, Healthcare statistics / epidemiology, Information provision, Prescribing and supply of medicines, Public Health Source Type: organizations
Relistor (methylnaltrexone bromide) approved in eu for opioid-induced constipation in palliative care setting
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Marketing approval has been granted in the EU for Relistor™ (methylnaltrexone bromide) subcutaneous injection for the treatment of opioid-induced constipation in patients with advanced illness receiving palliative care who have not responded adequately to usual laxative therapy. The drug is a peripherally acting mu-opioid receptor antagonist that reduces the constipating effects of opioids in the GI tract without affecting their ability to relieve pain. (Source: NeLM Headline News)
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: 1.2 Antispasmodics and other drugs altering gut motility, Motility and visceral sensation, Palliative care, 4.7.2 Opioid analgesics, Adverse Drug Reactions, New drugs, European Agency for the Evaluation of Medicinal Products (EMEA) Source Type: organizations
Review: inflammatory bowel disease in pregnancy
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The latest in a series of occasional articles about how to manage a pre-existing medical condition during pregnancy discusses inflammatory bowel disease; the following questions are addressed:
• How does pregnancy affect inflammatory bowel disease?
• How does inflammatory bowel disease affect the outcome of pregnancy and the baby?
• How is inflammatory bowel disease treated in pregnancy?
• What preconception advice should I give women with inflammatory bowel disease?
• How does inflammatory bowel disease affect fertility?
• Does breast feeding carry any risks? (Source: NeLM Headline News)
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: 8.2.2 Corticosteroids and other immunosuppressants, 1.5 Chronic bowel disorders, Drugs in pregnancy, General Advice, Information provision Source Type: organizations
North american menopause society issues position statement on hrt
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The North American Menopause Society (NAMS) has issued an updated position statement on the use of post-menopausal hormone replacement therapy (HRT). On the basis of current evidence, they suggest that starting HRT near the time of menopause has a positive risk to benefit balance. This becomes more unfavourable with ageing and time since menopause for untreated women.
The evidence-based position statement discusses the factors that affect a woman's risk and the benefits she may derive from HRT. There is good evidence that use improves most menopause-related symptoms and improves bone density. In recently post-menopausal ...
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: 6.4.1 Female sex hormones, Endocrinology, Obstetrics & amp; Gynaecology, Clinical guidelines Source Type: organizations
Npsa rapid response report: reducing dosing errors with opioid medicines
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The NPSA has issued a rapid response report on reducing dosing errors with opioid medicines, following reports of five deaths and over 4200 dose-related patient safety incidents up to June 2008. It states that every member of the team has a responsibility to check that the intended dose is safe for the individual patient, and knowledge of previous opioid dose is essential for the safe use of these products.
The agency has advised that when opioid medicines are prescribed, dispensed or administered, in anything other than acute emergencies, the healthcare practitioner concerned, or their clinical supervisor, should:
• ...
Source: NeLM Headline News - July 3, 2008 Category: Drugs & Pharmacology Tags: 4.7.2 Opioid analgesics, Pain control, General Advice, Medication errors, Drug Administration, Information provision, Prescribing and supply of medicines, National Patient Safety Agency (NPSA), Adverse Drug Reactions Source Type: organizations
