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This page shows you the most recent publications within this specialty of the MedWorm directory.

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Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. klotho protein content decreases with increasing age, which weakens resistance to oxidative stress, resulting in induced cell death as well as modulating endolymph fluid homeostasis. Down-regulation of klotho also leads to down-regulation of TRPV5 and TRPV6, resulting in modified Ca(2 +) homeostasis in the inner ear, dysfunction of sensory cell transduction and causing hearing loss and/or vestibular disorders. Objective. Expression of klotho, TRPV5 and TRPV6 in the mouse inner ear and age-related changes were analysed. Materials and methods. CBA/J mice aged 8 weeks and 24 months were used in this study. The lo...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Takumida M, Ishibashi T, Hamamoto T, Hirakawa K, Anniko M Tags: Acta Otolaryngol Source Type: journals

Expression of canonical transient receptor potential channel (TRPC) 1-7 in the mouse inner ear.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: It is suggested that TRPCs play a functional role in the sensory cell transduction system in the inner ear. Objective: To study expression of TRPC 1-7 in the mouse inner ear. Materials and methods: The localization of TRPC 1-7 in the inner ear of CBA/J mice was investigated by immunohistochemistry. Results: TRPC immunoreactivity was observed generally in the inner ear, e.g. in the lateral wall of the cochlea, organ of Corti, spiral ganglion, vestibular end organs and vestibular ganglion. The immunofluorescent reaction to TRPC 3, 4, 5, and 7 in the stria vascularis was more intense than in the spiral prominence ...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Takumida M, Anniko M Tags: Acta Otolaryngol Source Type: journals

Effectiveness of different approaches for establishing cisplatin-induced cochlear lesions in mice.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Mouse cochleae are highly resistant to systemicallyadministered cisplatin. However, cochlear lesions can be produced effectively in mice when cisplatin is applied locally through the round window niche or tympanum. Objective: To explore the optimal approach for creating cisplatin-induced cochlear lesions in mice. Materials and methods: Cisplatin was administered to adult C57BL/6J mice via four approaches: (1) transtympanic injection, (2) round window niche injection, (3) intraperitoneal injection (i.p.) at 4 mg/kg/day for 4 consecutive days, and (4) one 15 mg/kg dose i.p. The hearing was monitored using freque...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: He J, Yin S, Wang J, Ding D, Jiang H Tags: Acta Otolaryngol Source Type: journals

The impact of fixated glass ionomer cement and springy cortical bone incudostapedial joint reconstruction on hearing results.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Although it abolishes the incudostapedial joint, use of glass ionomer cement to repair the defect between the stapes head and the long process of the incus is a successful procedure when the hearing results are considered. Objectives: To compare the hearing results obtained by a fixed, stiff reconstruction with glass ionomer cement, and a flexible, springy pseudo-joint built with autologous cortical bone in patients with a small defect between the long process of the incus and the stapes head. Patients and methods: A total of 66 patients who had canal wall up tympanomastoidectomy due to chronic otitis media an...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Celik H, Aslan Felek S, Islam A, Demirci M, Samim E, Oztuna D Tags: Acta Otolaryngol Source Type: journals

Role of surgical management in temporal bone fibrous dysplasia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Surgical treatment of fibrous dysplasia of the temporal bone (TBFD) revealed relatively good outcomes. Also, active surgical intervention is necessary to prevent the formation of secondary cholesteatoma or other complications. In particular, FD involving the inner ear may require greater caution when deciding on the resection area and timing of surgery. Objectives: The purpose of this study was to analyze clinical manifestations of TBFD and its surgical outcomes. Patients and methods: Nine patients diagnosed with TBFD after surgery at three tertiary referral centers were included. Pre- and postoperative clinica...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Kim YH, Song JJ, Choi HG, Lee JH, Oh SH, Chang SO, Koo JW, Kim CS Tags: Acta Otolaryngol Source Type: journals

Contribution to morphological knowledge of the development of the human incudo-mallear joint.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: At the time of birth, the incudo-mallear joint is completely developed. Objective. To study the development of the incudo-mallear joint in human embryos and fetuses. Materials and methods. In all, 46 temporal bones with ages between 9 mm and newborns were studied. The preparations were cut in a series and dyed using Martins' trichrome technique. Results. The incudo-mallear joint acquires the characteristics of a saddle joint at 10 weeks of development. The cartilage that covers the articular surfaces is formed by different strata that develop successively: the superficial stratum at 14 weeks, the transitional b...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Cisneros Gimeno AI, Whyte Orozco JR, Nogues JA, Gotor CY, De La Torre MA, Orozco AW Tags: Acta Otolaryngol Source Type: journals

The functional and anatomical results of the canal wall down tympanoplasty in extensive cholesteatoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Although we have shown that malleus handle and mucosal factors were important prognostic factors for hearing, we were unable to show the positive effect of the stapes superstructure on hearing results. The positive effect of the presence of the stapes superstructure on hearing results is closely related to the quality of the mucosa. Objective: The aim of this study was to investigate the impact of ossicular and mucosal factors on hearing in primary canal wall down (CWD) surgery with ossicular chain reconstruction (OCR) performed for extensive acquired cholesteatoma. Patients and methods: A total of 134 adults w...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Aslan Felek S, Islam A, Celik H, Demirci M, Samim E, Kose SK Tags: Acta Otolaryngol Source Type: journals

Pelizaeus Merzbacher disease: morphological analysis of the vestibulo-cochlear system.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In agreement with previously published findings, our results demonstrate that Pelizaeus Merzbacher disease (PMD) does not affect the development and morphology of the peripheral vestibulo-cochlear system. Objective: PMD is a consequence of X-linked mutation of the main central nervous system (CNS) myelin protein resulting in a complex neurological syndrome. Otorhinolaryngological symptoms include nystagmus and alterations of auditory-evoked brainstem responses. To date no histopathological analysis of the inner ear has been performed. Materials and methods: The temporal bone morphology of an affected fetus was ...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Schmutzhard J, Schwentner I, Glueckert R, Sergi C, Beckmann F, Abraham I, Riechelmann H, Schrott-Fischer A, Müller B Tags: Acta Otolaryngol Source Type: journals

Three-dimensional video-oculography in patients with vestibular neuritis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The nystagmus recorded without visual fixation contained all three components in most patients with vestibular neuritis (VN). The nystagmus was unidirectional, strongly visually suppressed with the loss of vertical component in most patients, and it obeyed Alexander's law. Video-oculography (VOG) is a non-invasive tool for detailed analysis of nystagmus, and hence may improve differential diagnostics in dizzy patients. Objective: To characterize three-dimensional nystagmus findings in patients with acute VN using the VOG technique. Patients and methods: A prospective study in 16 patients with VN was carried ou...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Hirvonen TP, Aalto H Tags: Acta Otolaryngol Source Type: journals

Changes in audiometric thresholds before, during and after attacks of vertigo associated with Meniere's syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: No significant changes in hearing thresholds were observed during vertigo attacks associated with Meniere's disease. Objectives: To determine if the hearing alters during the period of the attacks of vertigo in Meniere's disease. Patients and methods: The study group consisted of patients who had a clinical diagnosis of definite Meniere's syndrome according to the AAOOHNS criteria, a score on the Gibson scale of 7 or over and an enhanced negative summating potential on transtympanic electrocochleography. These patients were supplied with a programmable hearing aid and a portable programmer that allowed them to ...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: McNeill C, Cohen MA, Gibson WP Tags: Acta Otolaryngol Source Type: journals

Meniere's disease and middle ear pressure - vestibular function after transtympanic tube placement.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although an effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa is used as a selection criterion. Objectives: Transtympanic ventilation tube insertion as a treatment option for MD has been reported but its results have been controversial. So far, no investigations on vestibular function in patients with MD after tube insertion have been carried out. Subjects and methods: Twenty-two patients with unilateral MD who were intractabl...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Park JJ, Chen YS, Westhofen M Tags: Acta Otolaryngol Source Type: journals

The ice-water caloric test.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Three possible results are commonly seen after ice-water caloric irrigation and to correctly interpret them the function of the corresponding vestibular receptor and of normal endolymphatic flow must be taken into account. Bedside vestibular examination helps to interpret discrepant findings. Objective: To review the findings obtained with the ice-water caloric test in patients with dizziness and to compare the results with those of the bedside test. Patients and methods: The study was undertaken in a university hospital, tertiary medical center. The indications to perform the ice-water caloric test were: 1) u...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Batuecas-Caletrio A, Montes-Jovellar L, Boleas-Aguirre MS, Perez-Fernandez N Tags: Acta Otolaryngol Source Type: journals

High-dose intratympanic gentamicin instillations for treatment of Meniere's disease: long-term results.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Administration of high-dose gentamicin for intractable Meniere's disease appears to be effective in achieving long-term control of vertigo. However, the safety of this route of administration with respect to the patient's hearing has not yet been sufficiently established. Objectives: The study aimed to analyze the long-term results of patients receiving high-dose intratympanic gentamicin (ITG) instillation for refractory Meniere's disease. Patients and methods: Fourteen patients with Meniere's disease according to 1995 American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guidelines who had failed...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Hsieh LC, Lin HC, Tsai HT, Ko YC, Shu MT, Lin LH Tags: Acta Otolaryngol Source Type: journals

Investigation of pitch discrimination and the effect of learning for virtual channels realized by current steering.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: As virtual channels could be perceived by the majority of implant users, they promise potential for advanced speech coding strategies, providing enhanced spectral resolution. An improvement in resolution was found from first stimulation up to 6 months afterwards. Objective: Independent current sources allow distribution of the current between adjacent electrode contacts in a defined ratio, thus steering the current. The goal of our study was to investigate a) whether all users were able to distinguish between adjacent physical channels, b) how many users could perceive a distinct pitch as the current was steere...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Brendel M, Frohne-Buechner C, Stoever T, Lenarz T, Buechner A Tags: Acta Otolaryngol Source Type: journals

A longitudinal study of hearing decline in women with Turner syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Young and middle-aged women with Turner syndrome (TS) have a progressive type of hearing impairment, deteriorating rapidly in adult age. The hearing decline seems to consist of two patterns: a mid-frequency dip, likely of a genetic origin, and a high-frequency loss resembling age-related hearing impairment - possibly influenced by estrogen deficiency. Objectives: This was a longitudinal study of hearing thresholds in a group of women with TS that also aimed to determine whether the factors initial age, initial hearing level, karyotype, and presence/absence of a mid-frequency dip influence the rate of decline an...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Hederstierna C, Hultcrantz M, Rosenhall U Tags: Acta Otolaryngol Source Type: journals

Implementation of perceptual channels in children implanted with a HiRes 90K device.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The increased spectral resolution that characterizes the HiRes 120 device contributes to improvement of performance. Discrimination and identification in noise are consistent with reports of improved perception under everyday listening situations. Objectives: This work focuses on speech perception findings after implementation of current steering in HiResolution strategy of children implanted with Clarion HiRes 90K. Subjects and methods: Comparison was made between three groups of children: standard HiRes control group, a second group switched over from HiRes to HiRes 120 and the third group switched on with H...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Mancini P, Bosco E, D'agosta L, Traisci G, Nicastri M, Capelli G, Ballantyne D, Filipo R Tags: Acta Otolaryngol Source Type: journals

Off-channel effect of high-frequency overstimulation on duration tuning of low-frequency inferior colliculus neurons in guinea pigs.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. High-frequency overstimulation can cause the loss of duration selectivity in low-frequency inferior colliculus neurons in guinea pigs. Objective. To investigate the effect of high-frequency overstimulation on duration tuning in low-frequency inferior colliculus neurons in guinea pigs. Materials and methods. Duration tuning pattern was recorded by measuring the spikes of single neurons in response to the best frequency (BF) of different durations. The effect of high-frequency overstimulation was verified by comparing the responses before and after the tone exposure. Results. In total, 40 duration-tuned neurons w...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Chen Z, Yu D, Feng Y, Su K, Wang J, Yin S Tags: Acta Otolaryngol Source Type: journals

Efficacy of selective percutaneous embolization for the treatment of intractable posterior epistaxis and juvenile nasopharyngeal angiofibroma (JNA).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Percutaneous embolization reduces the reappearance of epistaxis and the mean length of hospital stay for patients with intractable epistaxis or juvenile nasopharyngeal angiofibroma (JNA). Objectives. To assess whether percutaneous embolization is effective for the treatment of intractable epistaxis and JNA. Patients and methods. Twenty-eight patients with intractable posterior epistaxis treated by embolization (25 males; m = 59.78 years; SD = 14.3) and 28 unembolized patients (24 males; m = 59.21 years; SD = 15.13) were studied retrospectively. Eight patients with JNA (all males; mean = 16.5 years; SD = 2.35; f...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Santaolalla F, Araluce I, Zabala A, López A, Garay M, Sanchez JM Tags: Acta Otolaryngol Source Type: journals

Mometasone furoate nasal spray reduces symptoms and improves quality of life in Chinese patients with moderate to severe allergic rhinitis: a multicenter open-label study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: mometasone furoate nasal spray (MFNS) can reduce the symptoms and improve quality of life in Chinese patients with moderate to severe allergic rhinitis (AR). Objective: To evaluate the effects of MF on symptoms and quality of life in Chinese patients with moderate to severe AR. Patients and methods: In a multicenter and open-label study, 500 patients with moderate to severe AR were enrolled and received MFNS 200 microg once daily. We visited the patients four times (at baseline, and week 1, 2, and 4) to record symptom scores and the influence of AR on daytime activities and quality of sleep. The Mini Rhinoconju...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Zhang L, Xu G, Wang X, Liu S, Li Y, Wang S, Yang B, Zheng C, Wang C, Dong P, Lin Z, Zhang H, Han D Tags: Acta Otolaryngol Source Type: journals

Complication rates of radiofrequency surgery in the upper airways: a single institution experience.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Radiofrequency (RF) surgery of the upper airways appears to be a safe procedure with an acceptable incidence of minor and moderate complications. Objectives: RF surgery is increasingly used in the treatment of patients with sleep disordered breathing and inferior turbinate hypertrophy. Our aim was to investigate the incidence and the severity of the complications of RF surgery in the upper airways. Patients and methods: This was a retrospective, observational study at a tertiary care centre, academic teaching hospital during 1 year. Data from medical records were collected on 753 consecutive patients treated wi...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Bäck LJ, Liukko T, Sinkkonen ST, Ylikoski J, Mäkitie AA Tags: Acta Otolaryngol Source Type: journals

Dynamic upper airway changes during sleep in patients with obstructive sleep apnea syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different strategies should be selected in upper airway management. Objectives: To identify the sites of narrowing and evaluate dynamic upper airway movement in patients with obstructive sleep apnea syndrome (OSAS) while awake and asleep. Patients and methods: This study included 10 patients treated for OSAS between Au...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Chuang LP, Chen NH, Li HY, Lin SW, Chou YT, Wang CJ, Liao YF, Tsai YH Tags: Acta Otolaryngol Source Type: journals

Treatment outcome in patients undergoing surgery for carcinoma larynx and hypopharynx - a follow-up study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Compared with larynx cancers salvage rates are poorer for hypopharyngeal cancers and the role of primary surgery seems to be significantly higher and more decisive in overall survival (OS). Hypopharyngeal cancers therefore warrant a closer follow-up after an organ preservation protocol, to detect recurrence at the earliest stage and plan for an effective salvage surgery. Objective: To evaluate the survival and morbidity of patients treated by surgery for carcinoma of the larynx and hypopharynx according to site. Patients and methods: All patients who had undergone laryngectomy at the Division of Surgical Oncol...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Varghese BT, Sebastian P, Mathew A Tags: Acta Otolaryngol Source Type: journals

Nerve-muscle pedicle implantation facilitates re-innervation of long-term denervated thyroarytenoid muscle in rats.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Nerve-muscle pedicle (NMP) implantation was effective in the recovery from atrophic changes in long-term denervated thyroarytenoid (TA) muscle. Re-innervation occurred via the transferred nerve. However, the effectiveness of the NMP method may decline with increasing duration of denervation. Objectives: To evaluate the effects of NMP implantation on long-term denervated rat TA muscle. Materials and methods: Wistar rats (n=105) were divided into two groups in which the left recurrent laryngeal nerve (RLN) was transected without (DNV group) or with (NMP group) subsequent NMP implantation, and subgroups of each g...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Miyamaru S, Kumai Y, Ito T, Sanuki T, Yumoto E Tags: Acta Otolaryngol Source Type: journals

Endoscope-assisted partial-superficial parotidectomy through two small skin incisions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Endoscope-assisted partial-superficial parotidectomy is a feasible method for treatment of benign parotid superficial lobe tumors located at the anterior or the inferior of the auricular lobule. The main advantage of this procedure is that the small operative scar resulted in improved cosmetic results. Objectives. This study evaluated the feasibility of endoscope-assisted partial parotidectomy through two small skin incisions. Patients and methods. Thirty cases with benign parotid superficial lobe tumors with a diameter < 30 mm located at the anterior or the inferior of the auricular lobule underwent endosco...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Sun W, Xu YD, Zheng YQ, Liu X, Zeng L, Liu W, Huang X Tags: Acta Otolaryngol Source Type: journals

Surgical management of tracheal shaving for papillary thyroid carcinoma with tracheal invasion.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Patients showed improved quality of life following tracheal shaving and the carcinoma was well controlled locally, as long as invasion had not progressed to the mucosal surface of the trachea. However, compared with papillary thyroid carcinoma (PTC) with no tracheal invasion, metastasis was common and invasion of organs other than the trachea was frequent, putting many patients into the high-risk group. The clinical course for such patients thus requires careful monitoring, with particular attention to metastasis to other locations. Tracheal shaving can be recommended for patients with PTC with tracheal invasio...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Tsukahara K, Sugitani I, Kawabata K Tags: Acta Otolaryngol Source Type: journals

Head and neck cancer in young people: a series of 52 SCCs of the oral tongue in patients aged 35 years or less.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Prognosis was very poor as soon as a local failure developed. Up-front treatment should be optimized to control this rare disease. We propose producing and reporting recommendations via a concerted oncologic physician referral network. PMID: 19922105 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Mallet Y, Avalos N, Le Ridant AM, Gangloff P, Moriniere S, Rame JP, Poissonnet G, Makeieff M, Cosmidis A, Babin E, Barry B, Fournier C Tags: Acta Otolaryngol Source Type: journals

In situ tissue engineering of canine skull with guided bone regeneration.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Calcium alginate (CA) membrane prevents excessive fibrous tissue intrusion and/or dislocation of a bone scaffold. However, CA membrane did not always accelerate cranial bone regeneration. Objective: We previously reported skull regeneration using a bone substitute material (BSM), which consisted of collagen-coated beta-tricalcium phosphate and autologous bone fragments, and bone marrow-derived stromal cells (BSCs). However, excessive fibrous tissue intrusion or dislocation of the BSM occasionally interrupted bone regeneration. To avoid such problems, we examined CA membrane, which is useful for guided bone rege...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Umeda H, Kanemaru SI, Yamashita M, Ohno T, Suehiro A, Tamura Y, Hirano S, Nakamura T, Omori K, Ito J Tags: Acta Otolaryngol Source Type: journals

Clinical significance of measuring levels of tumor necrosis factor-alpha and soluble interleukin-2 receptor in nasopharyngeal carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Changes in tumor necrosis factor-alpha (TNF-alpha) and soluble interleukin-2 (sIL-2R) levels appear to be closely related to tumor progression and prognosis in nasopharyngeal carcinoma (NPC). Further investigation is suggested. Objectives: The study examined whether changes in TNF-alpha and sIL-2R in NPC can be used to predict tumor progression and prognosis. Patients and methods: The study was carried out in 58 patients with NPC newly diagnosed from December 2003 to December 2006 at a single institution and 60 control subjects of comparable age. Blood levels of TNF-alpha and sIL-2R were monitored before, durin...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Hsiao SH, Lee MS, Lin HY, Su YC, Ho HC, Hwang JH, Lee CC, Hung SK Tags: Acta Otolaryngol Source Type: journals

Commercially available high-speed system for recording and monitoring vocal fold vibrations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have developed a special purpose adaptor making it possible to use a commercially available high-speed camera to observe vocal fold vibrations during phonation. The camera can capture dynamic digital images at speeds of 600 or 1200 frames per second. The adaptor is equipped with a universal-type attachment and can be used with most endoscopes sold by various manufacturers. Satisfactory images can be obtained with a rigid laryngoscope even with the standard light source. The total weight of the adaptor and camera (including battery) is only 1010 g. The new system comprising the high-speed camera and the new adaptor c...
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Sekimoto S, Tsunoda K, Kaga K, Makiyama K, Tsunoda A, Kondo K, Yamasoba T Tags: Acta Otolaryngol Source Type: journals

Objective assessment of dry mouth using a non-invasive device.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19922109 [PubMed - as supplied by publisher] (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - November 21, 2009 Category: ENT & OMF Authors: Ishimoto SI, Tsunoda K, Akiya K, Fujimaki Y, Okada K, Kinoshita M, Yoshida T Tags: Acta Otolaryngol Source Type: journals

Guide for AuthorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Source Type: journals

Calendar of EventsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Source Type: journals

A child with lipoid proteinosis of larynx, skin and lymph nodesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We read with interest the article by Acar et al. in which they reported four cases of lipoid proteinosis (LP) of the larynx. LP also known as Urbach–Wiethe syndrome. This is an extremely rare autosomal recessive disorder characterised by hyaline and lipid deposits especially involving the upper respiratory tract and skin. Laryngeal lesion cause hoarseness and a weak cry as the first signs of the disease. The etiology remains unclear, but the symptoms relate to deposition of an amorphous eosinophilic hyaline-like material. This can occur in the skin, particularly around dermal microvessels, mucosa and sometimes internal o...
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Gürkan İş, Funda Çorapcıoğlu, Sinan Taş Tags: Letter to the Editor Source Type: journals

Evaluation for language and speech development in Kabuki make-up syndrome: A case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Kabuki make-up syndrome (KMS) is defined as a rare syndrome with mental retardation, growth deficiency and multiple anomalies of unknown cause. Cases have a characteristic facial appearance of broad and low auricles, wide forehead, broad and flattened nose root. In this article, 4-year, 10-month-old boy with speech delay reported due to characteristics of the facial appearance is considered as KMS, a rare syndrome. Otological, audiological and developmental evaluation of the patient consisted of six parameters. (1) ENT examination: normal. (2) Audiological findings were at normal hearing levels. (3) General devel...
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Nuray Bayar Muluk, Fulya Yalçınkaya, Bilgehan Budak, Selen Gündüz, Kıvanç Ayas Tags: Case reports Source Type: journals

Microdebrider resection of acquired subglottic cysts: Case series and review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The laryngeal microdebrider offers a safe and effective way to remove SGC with a low recurrence rate. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Evan R. Ransom, Marcelo B. Antunes, Lee P. Smith, Ian N. Jacobs Tags: Case reports Source Type: journals

Retrograde nasal intubation via the cleft in Pierre-Robin Sequence neonates: A case seriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Pierre-Robin Sequence, the triad of glossoptosis, micrognathia and cleft palate, provides a challenge in airway management both in and out of the operating room. Transnasal intubation is greatly preferred during its surgical intervention for maximum oral exposure in these very small patients without the added encumbrance of an oral endotracheal tube. From 2001 to 2009, three neonates with Pierre-Robin Sequence who underwent surgery to improve their airway had a novel method of securing a transnasal airway performed in the operating theater. After successful placement of a laryngeal mask airway (LMA) and subsequen...
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Joel E. Portnoy, Sherard Tatum Tags: Case reports Source Type: journals

Bacteremic methicillin-resistant Staphylococcus aureus deep neck abscess in a newborn—Case report and review of literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe an unusual localization of methicillin-resistant Staphylococcus aureus infection (MRSA) in a very young newborn. A 3-week-old male infant was admitted with fever, irritability, sialorrhea and stiffed left neck. The ENT examination revealed a deep neck mass and an ultrasound examination showed diffuse swelling of the left latero-pharyngeal area. A CT examination confirmed a deep neck abscess with difficult-to-define borders. Blood and nasopharyngeal cultures returned positive for MRSA. Treatment was started with intravenous teicoplanin and continued for 14 days with a marked decrease in abscess's dimensions and ...
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Oana Falup-Pecurariu, Eugene Leibovitz, Carmen Pascu, Cristian Falup-Pecurariu Tags: Case reports Source Type: journals

Successful treatment of isolated subglottic haemangioma with propranolol aloneEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe the successful treatment with propranolol, of a stridulous four-month-old child with a 95% obstructing subglottic haemangioma. This was achieved without the need for tracheostomy or any other surgical intervention, and with no reported side effects. We now believe the new discovery of a dramatic response to propranolol allows treatment in the acute setting and following further study may render surgical treatment of subglottic haemangioma obsolete. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Chris G. Jephson, Francesca Manunza, Samira Syed, Nikki A. Mills, John Harper, Ben E.J. Hartley Tags: Case reports Source Type: journals

Complete traumatic laryngotracheal disruption—A case report and reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Blunt neck trauma is an infrequent cause of injury in the pediatric population; however, significant injury is possible even with minor trauma to the neck. The authors present the previously unreported case of a combined laryngotracheal and esophageal disruption as well as a severe laryngeal crush injury in a pediatric patient following a blunt, clothesline neck injury. Immediate management of laryngotracheal or esophageal separation is frequently discussed, but little information exists concerning long-term treatment and management of total laryngotracheal disruption and crush injuries in pediatric patients. A r...
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: David F. Smith, Sara Rasmussen, Angela Peng, Charles Bagwell, Charles Johnson Tags: Case reports Source Type: journals

Migratory foreign body of neck in a battered baby: A case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report here a case of battered baby with homicidal marble ingestion which perforated the esophagus and migrated into the soft tissue of neck. It was diagnosed after 21 days asymptomatic period. The foreign body migrated into the tracheo-esophageal groove, lying deep to strap muscles, which was removed by neck exploration. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Jaimanti Bakshi, Roshan K. Verma, Saravanan Karuppiah Tags: Case reports Source Type: journals

Outpatient administration of radioactive iodine after total thyroidectomy for pediatric thyroid cancer: A report of three casesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Radioactive iodine is used as an anti-cancer reagent for papillary and follicular thyroid carcinomas. Patients that are administered a large dose of radioactive iodine are required to stay alone in an isolated room for several days. Some young children with thyroid carcinoma who cannot take care of themselves are not able to undergo this therapy. We tried outpatient administration of 131I for these patients. In Japan, administration for outpatients is restricted to 500MBq (13.5mCi). We administrated 13mCi 131I to three patients suffering from pediatric thyroid carcinomas. One patient with recurrent follicular car...
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Toru Takano, Katsunari Yane, Takaharu Oue, Naoki Otsuki, Ken-ichi Nibu, Yoh Hidaka Tags: Case reports Source Type: journals

Patency of nasopharynx and a cephalometric image in the children with orthodontic problemsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In cases of malocclusion of skeletal character, coexisting with adenoid hypertrophy, adenoidectomy should be carried out as early as possible. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Jarosław Wysocki, Marta Krasny, Piotr H. Skarżyński Tags: Research papers Source Type: journals

Is Carhart notch an accurate predictor of otitis media with effusion?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Significant CN is a sensitive diagnostic tool for detection of MEE but not specific. The diagnosis of OME in children requires a combinational diagnostic methods including tympanometry and audiometric variables especially CN. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: M. Shishegar, A. Faramarzi, N. Esmaili, S.T. Heydari Tags: Research papers Source Type: journals

Psychological stress and family functioning in mothers of children with allergic rhinitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Psychiatric symptoms observed in mothers of children with allergic rhinitis might be associated with child disease and the functioning of the entire family rather than features of the mother alone. Having a child with allergic rhinitis does not affect family functions according to the mother's aspect. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Ozkaya Emin, Solmaz Mustafa, Samancı Nedim Tags: Research papers Source Type: journals

Parents’ views on the quality of life of their children 2–3 years after cochlear implantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Parents report that cochlear implants affect their children in a wide variety of ways that cannot be summarized by a single scale. A broader descriptive framework is required to capture their experiences adequately. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: K. Huttunen, S. Rimmanen, S. Vikman, N. Virokannas, M. Sorri, S. Archbold, M.E. Lutman Tags: Research papers Source Type: journals

Evaluation of the upper airway in children and adolescents with cystic fibrosis and obstructive sleep apnea syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Bone and soft tissue structural alterations of the upper airway and chronic rhinosinusitis were associated with the OSAS group patients. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Regina Terse Trindade Ramos, Cristina Salles, Paloma Baiardi Gregório, Alessandro Tunes Barros, Angélica Santana, José Bouzas Araújo-Filho, Angelina Xavier Acosta Tags: Research papers Source Type: journals

Depressive emotioning in adolescents with cochlear implant and normal hearingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: As a result of these findings, it was thought that cochlear implantation had a positive effect on life quality and it was suggested that the adolescents and their families should get assistance from experts about the characteristics and principles of approaching the child in this period. The adolescent should be directed towards social activities and courses, their positive sides should be supported and further studies should be carried out with different case groups on this matter. In addition to, examining the interactions of hearing loss effects can help professionals determine the individuals who are at a ...
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Sanem Sahli, Umut Arslan, Erol Belgin Tags: Research papers Source Type: journals

Prevalence of habitual snoring and symptoms of sleep-disordered breathing in adolescentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: We found the prevalence of habitual snoring to be 4.0% in adolescents from the province of Manisa, Turkey which is low compared to previous studies. Habitual snoring is an important problem in adolescents and habitual snorers had significantly more nighttime symptoms of sleep-disordered breathing compared to non-snorers. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Ayhan Sogut, Ozge Yilmaz, Gonul Dinc, Hasan Yuksel Tags: Research papers Source Type: journals

Validation of the LittlEARS® Auditory Questionnaire in children with normal hearingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The LittlEARS® Auditory Questionnaire is a valid, language-independent tool for assessing the early auditory behaviour of infants and toddlers with normal hearing. The results of this study suggest that the LittlEARS® Auditory Questionnaire could also be very useful for documenting children's progress with their current amplification, providing evidence of the need for implantation, or highlighting the need for follow-up in other developmental areas. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: F. Coninx, V. Weichbold, L. Tsiakpini, E. Autrique, G. Bescond, L. Tamas, A. Compernol, M. Georgescu, I. Koroleva, G. Le Maner-Idrissi, W. Liang, J. Madell, B. Mikić, A. Obrycka, A. Pankowska, A. Pascu, R. Popescu, L. Radulescu, T. Rauhamäki, P. Rouev, Tags: Research papers Source Type: journals

Effect of lipooligosaccharide mutations of Haemophilus influenzae on the middle and inner earsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: LOS mutants of NTHi appear to have a reduced ability to pass through the round window membrane resulting in less inner ear inflammation and pathological changes. (Source: International Journal of Pediatric Otorhinolaryngology)
Source: International Journal of Pediatric Otorhinolaryngology - November 20, 2009 Category: ENT & OMF Authors: Patricia A. Schachern, Vladimir Tsuprun, Beinan Wang, Michael A. Apicella, Sebahattin Cureoglu, Michael M. Paparella, Steven K. Juhn Tags: Research papers Source Type: journals