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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.

Mitochondria toxin-induced acute cochlear cell death indicates cellular activity-correlated energy consumption
Abstract  The different cell types within the cochlea may have a specific contribution to the pathological changes during metabolism failure, which may provide clues for developing novel strategies for inner ear therapy. In order to evaluate activity-correlated cell death during metabolism failure in the cochlea, 3-nitropropionic acid was used to irreversibly inhibit the respiratory chain. Dose–response of the cochlear cells to 3-nitropropionic acid was analyzed in vitro. 3-Nitropropionic acid was administered onto the round window of guinea pigs. Cell death was identified by terminal transferase labeling t...
Source: European Archives of Oto-Rhino-Laryngology - November 25, 2012 Category: ENT & OMF Tags: European Archives of Oto-Rhino-Laryngology Source Type: research

Fixation of mandibular angle fractures: clinical studies
Conclusions  Prospective randomized controlled studies of MAFs repair techniques are scarce. The available data at best predict that complications are associated with all kinds of fixation techniques. The similar results of complications in studies using different methods of fixation indicate that biomechanics are only one factor to be considered when treating MAFs. A second fracture in the mandible (which was observed in the majority of the studies’ population) can confound the outcome data because the fixation requirements of a double fracture are often different from those for an isolated fracture. It ca...
Source: Oral and Maxillofacial Surgery - November 25, 2012 Category: ENT & OMF Tags: Oral and Maxillofacial Surgery Source Type: research

Botulinum toxin treatment of salivary fistulas following parotidectomy: follow-up results
Conclusion  In summary, botulinum toxin injections into the parotid tissue remaining after surgery appear to be an effective treatment for salivary fistulas following parotidectomy. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s10006-012-0375-0Authors Rainer Laskawi, Department of Otorhinolaryngology, University of Göttingen Medical Center, Robert-Koch-Str. 40, 37075 Göttingen, Lower Saxony, GermanyJan Winterhoff, Department of Otorhinolaryngology, University of Göttingen Medical Center, Robert-Koch-Str. 40, 37075 Göttingen, Lower Saxony, GermanySabrina Köhler, Depart...
Source: Oral and Maxillofacial Surgery - November 25, 2012 Category: ENT & OMF Tags: Oral and Maxillofacial Surgery Source Type: research

Oral myiasis: case report and review of literature
Abstract Introduction  The term myiasis is applied to the injurious action that larvae of certain Diptera cause in vertebrate animals by growing in living or dead tissue. Because of its great destructive potential, appropriate and preventive treatment is necessary. Oral myiasis is a rare pathology in humans and is associated with poor oral hygiene, alcoholism, senility, suppurating lesion, severe halitosis, and other conditions. Method  We have presented a case of oral myiasis in a mentally challenged patient. Results  Reviewing the literature revealed that most of the case...
Source: Oral and Maxillofacial Surgery - November 25, 2012 Category: ENT & OMF Tags: Oral and Maxillofacial Surgery Source Type: research

Nerve Growth Factor induced after Temporomandibular Joint Inflammation Decelerates Chondrocyte Differentiation
ConclusionsNGF‐TrkA signaling in the TMJ provides potentially a means of protection against the development of osteoarthritis by decelerating chondrocyte differentiation. This discovery may lead to the development of novel therapies for osteoarthritis of the TMJ and other joints.© 2012 John Wiley & Sons A/S
Source: Oral Diseases - November 24, 2012 Category: ENT & OMF Authors: Hechang Huang, Gregory Shank, Li Ma, Ross H Tallents, Stephanos Kyrkanides Tags: Original Article Source Type: research

In Children With Prader-Willi Syndrome, Adenotonsillectomy May Help Resolve Obstructive Sleep Apnea
Children with Prader-Willi syndrome may receive relief from sleep disorders after undergoing an adenotonsillectomy, suggests a new study from Nationwide Children's Hospital published in the November print issue of the Archives of Otolaryngology-Head and Neck Surgery. "Patients with Prader-Willi syndrome are at risk for sleep disordered breathing as growth hormone commonly used to treat their condition can cause the tonsils and adenoids to enlarge," said the study's lead author Kris Jatana, MD, FAAP, with Otolaryngology Head & Neck Surgery at Nationwide Children's...
Source: Health News from Medical News Today - November 23, 2012 Category: Consumer Health News Tags: Ear, Nose and Throat Source Type: news

Safety of thromboprophylaxis after oncologic head and neck surgery. Study of 1018 patients
ConclusionsOur analysis shows no benefit from chemoprophylaxis in oncologic head and neck surgery patients, with no VTE events. Our analysis shows higher rates of morbid side effects from using chemoprophylaxis, and we therefore conclude that chemoprophylaxis should not be routinely used. © 2012 Wiley Periodicals, Inc. Head Neck, 2012
Source: Head and Neck - November 22, 2012 Category: ENT & OMF Authors: Haim Gavriel, Evan Thompson, Stephen Kleid, SorWay Chan, Andrew Sizeland Tags: Original Article Source Type: research

Healing acceleration in hamsters of oral mucositis induced by 5-fluorouracil with topical Calendula officinalis
Conclusions: Calendula officinalis extract accelerated the healing of oral mucositis in hamsters.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 22, 2012 Category: ENT & OMF Authors: Nader Tanideh, Parisa Tavakoli, Mohammad Ali Saghiri, Franklin Garcia-Godoy, Dariush Amanat, Azadeh Andisheh Tadbir, Soleiman Mohammadi Samani, Amin Tamadon Tags: Oral Medicine Source Type: research

Effect of single-dose extended-release oral azithromycin on anticoagulation status in warfarinized patients
Conclusions: The results of this study suggest that prophylactic administration of AZ-ER to patients receiving daily warfarin therapy with a stable coagulation status has no relevant effect on the anticoagulant effect of warfarin.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 22, 2012 Category: ENT & OMF Authors: Yuji Kusafuka, Hiroshi Kurita, Shinichi Sakurai, Shigeru Suzuki, Yoshitaka Nakanishi, Yoshihiko Katsuyama, Shigeru Ohmori Tags: Medical Management and Pharmacology Update Source Type: research

[Tongue base schwannoma in a child.]
DISCUSSION: The particularities of this report are the patient's very young age and the tumor's tongue base location. The prognosis is usually good after complete excision, if there is only one tumor. Type 2 neurofibromatosis should be excluded, given the risk of malignant degeneration. PMID: 23182691 [PubMed - as supplied by publisher]
Source: Revue de Stomatologie et de Chirurgie Maxillo-Faciale - November 22, 2012 Category: ENT & OMF Authors: Bouguila J, Khalef I, Benali M, Sriha B, Soyah N, Boughammoura L Tags: Rev Stomatol Chir Maxillofac Source Type: research

Saliva: a ‘solubilizer’ of lipophilic antioxidant polyphenols
Source: Oral Diseases - November 22, 2012 Category: ENT & OMF Authors: I Ginsburg, R Kohen, E Koren Tags: Letter to the Editor Source Type: research

Prevalence of Oral Lesions of Autoimmune Etiology in Patients with Primary Sjögren's Syndrome
ConclusionThe results of our analysis suggest that patients with pSS have a 12% prevalence of OLAIE with a wide range (7.3%‐21.2%) found between practices. This difference is likely related to the different screening protocols for oral dryness between sites.© 2012 John Wiley & Sons A/S
Source: Oral Diseases - November 22, 2012 Category: ENT & OMF Authors: K Likar, C Stewart, I Al‐Hashimi, W Curtis, K Berg, K Cherian, PB Lockhart, MT Brennan Tags: Original Manuscript Source Type: research

Soft tissue stability after segmental distraction of the anterior mandibular alveolar process: a 5.5 year follow-up
Abstract: Soft tissue changes were analysed retrospectively in 17 patients following distraction osteogenesis (DO) of the mandibular anterior alveolar process. Lateral cephalograms were traced by hand, digitized, superimposed, and evaluated at T1 (17.0 days), after DO at T2 (mean 6.5 days), at T3 (mean 24.4 days), at T4 (mean 2.0 years), and at T5 (mean 5.5 years). Statistical analysis was carried out using Kolmogorov–Smirnov test, paired t-test, Pearson's correlation coefficient, and linear backward regression analysis. 5.5 years postoperatively, the net effect for the soft tissue at point B′ was 88% of the advancemen...
Source: International Journal of Oral and Maxillofacial Surgery - November 21, 2012 Category: ENT & OMF Authors: C.U. Joss, A. Triaca, M. Antonini, S. Kiliaridis, A.M. Kuijpers-Jagtman Tags: Orthognathic Surgery Source Type: research

Neutralizing antibody against granulocyte/macrophage colony–stimulating factor inhibits inflammatory response in experimental otitis media
Conclusions:Systemic injection of granulocyte/macrophage colony–stimulating factor neutralizing antibody inhibits the middle ear inflammation induced by lipopolysaccharide in mice. Our findings suggest that granulocyte/macrophage colony–stimulating factor may offer a novel therapeutic target for the management of intractable otitis media.
Source: The Laryngoscope - November 21, 2012 Category: ENT & OMF Authors: Shin Kariya, Mitsuhiro Okano, Takaya Higaki, Seiichiro Makihara, Takenori Haruna, Motoharu Eguchi, Kazunori Nishizaki Tags: Otology/Neurotology Source Type: research

Bilateral pharyngocele surgery under local anesthesia: Let the patient help the surgeon
Source: The Laryngoscope - November 21, 2012 Category: ENT & OMF Authors: Igor Leuchter, Minerva Becker, Pavel Dulguerov Tags: Head and Neck Source Type: research

Standardized letter of recommendation for otolaryngology residency selection
Conclusions:SLORs require little writing time, save reviewing time, and are easier to review compared to NLORs. Our SLOR had higher inter‐rater reliability in four of seven categories and was correlated with our rank list. This tool conveys standardized information in an efficient manner.
Source: The Laryngoscope - November 21, 2012 Category: ENT & OMF Authors: Jonathan N. Perkins, Conan Liang, Kim McFann, Mona M. Abaza, Sven‐Olrik Streubel, Jeremy D. Prager Tags: General Otolaryngology Source Type: research

A novel approach for surgical repair of dehiscent high jugular bulb
Source: The Laryngoscope - November 21, 2012 Category: ENT & OMF Authors: Mohammad F. Shaikh, Hossein Mahboubi, Michael German, Hamid R. Djalilian Tags: Otology/Neurotology Source Type: research

Cervical Vertebral Maturation of Female Children With Orofacial Clefts.
Conclusions :  Girls with cleft lip and/or palate are at a higher risk of delayed pubertal growth. PMID: 23167817 [PubMed - as supplied by publisher]
Source: The Cleft Palate-Craniofacial Journal - November 20, 2012 Category: ENT & OMF Authors: Li W, Sun L Tags: Cleft Palate Craniofac J Source Type: research

Superparamagnetic iron oxide-enhanced interstitial magnetic resonance lymphography to detect a sentinel lymph node in tongue cancer patients.
Conclusion: This is the first report on human sentinel node (SN) detection by interstitial magnetic resonance (MR) lymphography with superparamagnetic iron oxide (SPIO) in tongue cancer patients who also underwent lymphoscintigraphy. Our results indicate that further studies are warranted, as this novel method may replace current scintigraphic techniques. Objectives: To examine the feasibility of interstitial MR lymphography using SPIO for SN detection in the head and neck region. Methods: MR images were acquired sequentially at 10 min, 30 min, and 24 h after submucosally injecting 0.1 ml SPIO (ferucarbotran) around the tu...
Source: Acta Oto-Laryngologica - November 20, 2012 Category: ENT & OMF Authors: Mizokami D, Kosuda S, Tomifuji M, Araki K, Yamashita T, Shinmoto H, Shiotani A Tags: Acta Otolaryngol Source Type: research

The midline electroneurography method for facial palsy reflects total nerve degeneration.
Conclusion: The midline electroneurography (ENoG) method might reflect total facial nerve degeneration. Objective: We compared ENoG values in patients with facial palsy using two different methods, the midline method and five electroneurogram recordings, to reveal whether the ENoG value obtained with the midline method reflects total facial nerve degeneration. Methods: Forty patients with facial palsy were enrolled. Compound muscle action potentials (CMAPs) were recorded using the midline method, in which the anode was placed on the mental protuberance and the cathode was placed on the philtrum. Additionally, five electron...
Source: Acta Oto-Laryngologica - November 20, 2012 Category: ENT & OMF Authors: Wada SI, Haginomori SI, Mori A, Ichihara T, Kanazawa A, Kawata R, Takubo T, Yorifuji S Tags: Acta Otolaryngol Source Type: research

Genetic analysis of PAX3 for diagnosis of Waardenburg syndrome type I.
Conclusion: PAX3 genetic analysis increased the diagnostic accuracy for Waardenburg syndrome type I (WS1). Analysis of the three-dimensional (3D) structure of PAX3 helped verify the pathogenicity of a missense mutation, and multiple ligation-dependent probe amplification (MLPA) analysis of PAX3 increased the sensitivity of genetic diagnosis in patients with WS1. Objectives: Clinical diagnosis of WS1 is often difficult in individual patients with isolated, mild, or non-specific symptoms. The objective of the present study was to facilitate the accurate diagnosis of WS1 through genetic analysis of PAX3 and to expand the spec...
Source: Acta Oto-Laryngologica - November 20, 2012 Category: ENT & OMF Authors: Matsunaga T, Mutai H, Namba K, Morita N, Masuda S Tags: Acta Otolaryngol Source Type: research

Reliability and validity of the Italian self‐evaluation of communication experiences after laryngeal cancer questionnaire
ConclusionPreliminary evidence supports the convergent validity, test‐retest reliability, and internal consistency of the I‐SECEL, notwithstanding low internal consistency and test–retest reliability for 1 subscale. © 2012 Wiley Periodicals, Inc. Head Neck, 2012
Source: Head and Neck - November 20, 2012 Category: ENT & OMF Authors: Antonio Schindler, Francesco Mozzanica, Francesca Brignoli, Patrizia Maruzzi, Paul Evitts, Francesco Ottaviani Tags: Original Article Source Type: research

Continuous intraoperative vagus nerve stimulation for identification of imminent recurrent laryngeal nerve injury
ConclusionCIONM reliably signaled impending nerve injury, enabling immediate corrective action. © 2012 Wiley Periodicals, Inc. Head Neck, 2012
Source: Head and Neck - November 20, 2012 Category: ENT & OMF Authors: Rick Schneider, Gregory W. Randolph, Carsten Sekulla, Eimear Phelan, Phuong Nguyen Thanh, Michael Bucher, Andreas Machens, Henning Dralle, Kerstin Lorenz Tags: Original Article Source Type: research

Speech rehabilitation during the first year after total laryngectomy
ConclusionsSpeech improves considerably between 6 months and 1 year after total laryngectomy. Nonattendance of rehabilitation is associated with a worse functional outcome in speech rehabilitation. Head Neck, 2012
Source: Head and Neck - November 20, 2012 Category: ENT & OMF Authors: Susanne Singer, Dorit Wollbrück, Andreas Dietz, Juliane Schock, Friedemann Pabst, Hans‐Joachim Vogel, Jens Oeken, Annett Sandner, Sven Koscielny, Karl Hormes, Kerstin Breitenstein, Heike Richter, Andreas Deckelmann, Sarah Cook, Michael Fuchs, Sylvia Me Tags: Original Article Source Type: research

Sharing a diagnosis of HPV‐related head and neck cancer: The emotions, the confusion, and what patients want to know
ConclusionsAdditional educational resources explaining the facts about HPV in HNSCC in a consistent way including content of highest priority to patients may improve understanding of HPV. © 2012 Wiley Periodicals, Inc. Head Neck, 2012
Source: Head and Neck - November 20, 2012 Category: ENT & OMF Authors: Shrujal S. Baxi, Andrew G. Shuman, Geoffrey W. Corner, Elyse Shuk, Eric J. Sherman, Elena B. Elkin, Jennifer L. Hay, David G. Pfister Tags: Original Article Source Type: research

High symptom burden prior to radiation therapy for head and neck cancer: A patient‐reported outcomes study
ConclusionsA substantial proportion of patients were experiencing high symptom burden. Because few interventions currently exist for several of the most problematic symptoms, research in symptom reduction that targets the pattern of symptoms described here is greatly needed. © 2012 Wiley Periodicals, Inc. Head Neck, 2012
Source: Head and Neck - November 20, 2012 Category: ENT & OMF Authors: G. Brandon Gunn, Tito R. Mendoza, Clifton D. Fuller, Ibrahima Gning, Steven J. Frank, Beth M. Beadle, Ehab Y. Hanna, Charles Lu, Charles S. Cleeland, David I. Rosenthal Tags: Original Article Source Type: research

Clinical assessment is an accurate predictor of which patients will need septoplasty
Conclusions:Clinical assessment at initial presentation of patients with nasal obstruction and deviated septum is highly accurate in predicting which patients will need septoplasty.
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: Ahmad R. Sedaghat, Nicolas Y. Busaba, Michael J. Cunningham, David A. Kieff Tags: General Otolaryngology Source Type: research

Nasal backflow and the difficulty of relaxation in the upper esophageal sphincter
Conclusion:Nasal backflow was closely associated with the presence of aspiration; the opening of upper esophageal sphincters significantly decreased in the cases of nasal backflow.
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: Jin‐Woo Park, Bum Sun Kwon, Ji Hae Chang, Kyoung Bo Sim Tags: Laryngology Source Type: research

Effects of tensor tympani muscle contraction on the middle ear and markers of a contracted muscle
Conclusions:These markers should be searched for in otologic pathology states where the tensor tympani is suspected of being hypercontracted.
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: Manohar Bance, Fawaz M. Makki, Philip Garland, Wael A. Alian, Rene G. van Wijhe, Julian Savage Tags: Otology/Neurotology: Triological Society Candidate Thesis Source Type: research

Periostin may play a protective role in the development of eosinophilic chronic rhinosinusitis with nasal polyps in a mouse model
Conclusions:The loss of periostin appears to enhance polyplike lesion formation and mast cell infiltration in a mouse model of eosinophilic rhinosinusitis with nasal polyps.
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: Sang‐Wook Kim, Jin Hyun Kim, Myeong Hee Jung, Dong Gu Hur, Hong‐Kyoung Lee, Sea‐Yuong Jeon, Dae Woo Kim Tags: Allergy/Rhinology Source Type: research

Total soft palate reconstruction using the palatal island and lateral pharyngeal wall flaps
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: William E. Karle, Sumeet M. Anand, Jason B. Clain, Sophie Scherl, Mark L. Urken Tags: Head and Neck Source Type: research

Nasal manifestations of immunoglobulin G4‐related disease
Conclusions:The inflammatory lesions associated with IgG4‐related disease exist on the nasal membrane. Thus, the nasal manifestations of IgG4‐related disease were thought to be different from AR.
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: Masanobu Suzuki, Yuji Nakamaru, Shigeru Akazawa, Takatsugu Mizumachi, Masanori Maeda, Dai Takagi, Kanako C. Hatanaka, Satoshi Fukuda Tags: Allergy/Rhinology Source Type: research

Intraoral removal of stones in the proximal submandibular duct: Usefulness of a surgical landmark for the hilum
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: Hae Sang Park, So Young Pae, Kyung Yeon Kim, Sung Min Chung, Han Su Kim Tags: Head and Neck Source Type: research

Drug‐induced sleep endoscopy for upper airway evaluation in children with obstructive sleep apnea
Conclusion:The oropharynx/lateral walls are the most common site of obstruction in children with single site obstruction. Combined oropharynx/lateral walls and velum obstruction was the most common sites of obstruction in children with multiple site obstruction. Children with grade I and grade II tonsils may suffer from complete airway obstruction. DISE is a useful tool to identify upper airway obstruction sites in addition to adenotonsillar hypertrophy.
Source: The Laryngoscope - November 20, 2012 Category: ENT & OMF Authors: Seckin O. Ulualp, Peter Szmuk Tags: Sleep Medicine Source Type: research

Inhaled foreign bodies in children: A global perspective on their epidemiological, clinical, and preventive aspects
ConclusionsFew countries have good systematic data collection and there's a lack of sensibility in parents and clinicians in terms of acknowledge of the choking risk. On the contrary, international surveillance systems able to collect information in a standardized way need to be implemented. Pediatr Pulmonol. © 2012 Wiley Periodicals, Inc.
Source: Pediatric Pulmonology - November 20, 2012 Category: Respiratory Medicine Authors: Francesca Foltran, Simonetta Ballali, Hugo Rodriguez, Arjan B. (Sebastian) van As, Desiderio Passali, Achal Gulati, Dario Gregori Tags: Original Article: Epidemiology Source Type: research

Identification and characterization of the bacterial etiology of clinically problematic acute otitis media after tympanocentesis or spontaneous otorrhea in German children
Conclusions: NTHi, S. pneumoniae and S. pyogenes are implicated as important causes of complicated AOM in children in Germany. NTHi disease appears prevalent in all ages. The impact of vaccination to prevent NTHi and S. pneumoniae AOM may be substantial in this population and is worth investigating.
Source: BMC Infectious Diseases - November 20, 2012 Category: Infectious Diseases Authors: Gerhard GreversSusanne WiedemannJan-Christof BohnRolf-Werner BlasiusThomas HarderWerner KroenigerVolker VetterJean-Yves PirçonCinzia Marano Source Type: research

Information for Readers
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Tags: Frontmatter Source Type: research

Editorial Board
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Tags: Frontmatter Source Type: research

Contents
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Tags: Frontmatter Source Type: research

Acknowledgment of Reviewers
The editors of Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology thank the following reviewers and editorial board members for their dedication and time-consuming work on behalf of the journal during the period from July 1, 2011 through June 30, 2012. They have provided rigorous peer review of submissions necessary to ensure that readers of the journal receive sound and reliable information.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Tags: Acknowledgment of Reviewers Source Type: research

Prevalence of cone beam computed tomography imaging findings according to the clinical stage of bisphosphonate-related osteonecrosis of the jaw
Conclusion: Cancellous bone destruction, cortical bone erosion, sequestration, and osteosclerosis can be seen across all stages and prevalence seems to decrease with decreasing severity of BRONJ. The occurrence of periosteal new bone formation seems to start in high-stage BRONJ.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Frank Wilde, Marcus Heufelder, Kai Lorenz, Susanne Liese, Jan Liese, Jens Helmrich, Alexander Schramm, Alexander Hemprich, Edgar Hirsch, Karsten Winter Tags: Oral and Maxillofacial Radiology Source Type: research

Calcifying cystic odontogenic tumor and adenomatoid odontogenic tumor: radiographic evaluation
Conclusions: Radiolucency with numerous radiopaque foci (particularly when the radiolucency surrounds a portion of the root or entire tooth) is suggestive of an AOT rather than a CCOT.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Jira Chindasombatjaroen, Sopee Poomsawat, Naoya Kakimoto, Hiroaki Shimamoto Tags: Oral and Maxillofacial Radiology Source Type: research

Incidental pneumoparotid detected on computed tomography: Should it raise an alarm?
Conclusions: Pneumoparotid may be an incidental finding in patients asked to blow air in a closed mouth during CT/magnetic resonance acquisition. An awareness of this benign finding would prevent sudden alarm of interpreting it as an anaerobic infection of the parotid in such patients.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Chirag Kamal Ahuja, Mukesh Kumar Yadav, Vivek Gupta, Niranjan Khandelwal Tags: Oral and Maxillofacial Radiology Source Type: research

Histopathological features of bisphosphonate-associated osteonecrosis: findings in patients treated with partial mandibulectomies
The present study investigated the histopathologic and radiographic features of stage 3 bisphosphonate–associated osteonecrosis of the jaw (BAONJ) in patients who were treated with partial mandibulectomies. Bisphosphonates had been orally administered to 10 patients with osteoporosis and intravenously administered to 1 patient with metastatic carcinoma. On radiographic images, massive osteolysis and periosteal bone formations were conspicuous, and a thin mandibular cortical width was observed in 5 of 10 osteoporosis patients despite the previous use of bisphosphonate. Microscopically, the mandibulectomy specimens of the ...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Young-Ah Cho, Hye-Jung Yoon, Jae-Il Lee, Sam-Pyo Hong, Seong-Doo Hong Tags: Oral and Maxillofacial Pathology Source Type: research

BRAF and GNAQ mutations in melanocytic tumors of the oral cavity
Conclusions: The finding of BRAF mutations in oral benign and malignant melanocytic lesions points to a potential initiating role of BRAF in malignant transformation, which may have important therapeutic implications as those with BRAF mutations may benefit from specific treatment using RAF inhibitors.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Yoram Cohen, Nitza Goldenberg-Cohen, Sharon Akrish, Tali Shani, Ninette Amariglio, Olga Dratviman-Storobinsky, Ilana Kaplan, Iris Barshack, Abraham Hirshberg Tags: Oral and Maxillofacial Pathology Source Type: research

Osteogenic genes related to the canonic WNT pathway are down-regulated in ameloblastoma
Conclusions: These findings suggest that WNT-related bone-forming genes are down-regulated in ameloblastoma. Concurrent sFRP-2 overexpression suggests that both bone-forming and bone-inhibiting genes equally contributed to reduced bone formation in this neoplasm.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Gulsan A. Sathi, Hidetsugu Tsujigiwa, Satoshi Ito, Chong Huat Siar, Naoki Katase, Ryo Tamamura, Hidemitsu Harada, Hitoshi Nagatsuka Tags: Oral and Maxillofacial Pathology Source Type: research

Metagenomic investigation of microbes and viruses in patients with jaw osteonecrosis associated with bisphosphonate therapy
Conclusions: Individuals with jaw osteonecrosis harbored different microbial assemblages than nonaffected patients, and in general viral abundance and prophage induction increased with biofilm formation, suggesting that biofilm formation encouraged lysogenic interactions between viruses and microbial hosts and may contribute to pathogenicity.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Parish P. Sedghizadeh, Shibu Yooseph, Douglas W. Fadrosh, Lisa Zeigler-Allen, Mathangi Thiagarajan, Hamid Salek, Farid Farahnik, Shannon J. Williamson Tags: Oral and Maxillofacial Pathology Source Type: research

The relationship of denosumab pharmacology and osteonecrosis of the jaws
Denosumab is a new bone antiresorptive agent that has received approval by the Food and Drug Administration for use in patients with osteoporosis and metastatic cancer to the bones. Like the bisphosponates that are used as antiresorptive medications, denosumab has been associated with osteonecrosis of the jaws (ONJ). However, because the pharmacodynamics and pharmacokinetics of denosumab differ from that of the bisphosphonates, ONJ related to denosumab may resolve more rapidly with a drug holiday than bisphosphonate-related osteonecrosis of the jaws (BRONJ). This paper describes the management of a patient who developed ON...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: John Malan, Kyle Ettinger, Erich Naumann, O. Ross Beirne Tags: Medical Management and Pharmacology Update Source Type: research

Medical school–based education in dentistry: an exciting history and an opportune future
Medical school–based education for dentists has resulted in propelling some of the greatest advances in medicine and surgery of the past century. Varaztad Kazanjian, DMD, MD, a professor of prosthodontics at Harvard, returned from the Great War to train in medicine. He became a leader in the treatment of trauma and edentulism and was a principle founder of the specialty of plastic surgery. His procedures and instruments are in use today. Reed Dingman, DDS, MD, the first general practice resident in dentistry, became interested in head and neck cancer and trauma, returned to medical school, and was a pioneer in the develo...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Authors: Leon Assael Tags: Editorial Source Type: research

Society Page
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - November 19, 2012 Category: ENT & OMF Source Type: research