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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

Antibiotics for otitis media with effusion in children
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Authors: M. Daniel Tags: Editorial Comment Source Type: research

Up‐to‐date expert opinion referencing the best evidence available on intraoperative cerebrospinal fluid leak during endoscopic sinus surgery
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Authors: H.A. Reefy, C. Hopkins Tags: What I Do If Things Go Wrong Source Type: research

Young nasopharyngeal cancer patients with radiotherapy and chemotherapy are most prone to ischaemic risk of stroke: a national database, controlled cohort study
ConclusionsPatients with nasopharyngeal carcinoma are at an elevated risk of ischaemic stroke, without significant difference among treatment modalities. The relative risk is more prominent in younger patients. Comorbidity may enhance the risk.
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Authors: Chu C.‐N., Chen P.‐C., Bai L.‐Y., Muo C.‐H., Sung F.‐C., Chen S.‐W. Tags: Original Article Source Type: research

Utility of quantitative 18F‐fluorodeoxyglucose uptake measurement to identify occult tonsillar carcinoma in patients with cervical metastasis of unknown primary tumours: a retrospective case–control study
Conclusion18F‐fluorodeoxyglucose positron emission tomography/computerised tomography with tonsil SUVmax measurement is useful to identify occult tonsillar squamous cell carcinoma.
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Authors: Lee H.J., Kim J.S., Roh J.‐L., Lee J.H., Cho K.‐J., Park G.C., Choi S.‐H., Nam S.Y., Kim S.Y. Tags: Original Article Source Type: research

Acoustic rhinometry, rhinomanometry and visual analogue scale before and after septal surgery: a prospective 10‐year follow‐up
ConclusionsWe found an increase in acoustic values, but an increase in nasal resistance in the long‐term follow‐up. Other factors than nasal area may have an impact on nasal resistance and the feeling of nasal obstruction. The small size on the sample interfered with the results.
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Authors: L.E. Haavisto, J.I. Sipilä Tags: Original Article Source Type: research

Announcement
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Tags: Announcement Source Type: research

Cochrane Colloquium systematic review travel award
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Source Type: research

Acknowledgements to Reviewers
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Tags: Acknowledgements to Reviewers Source Type: research

Clinical Otolaryngology News Issue 36, 2012
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Tags: Clinical Otolaryngology News Source Type: research

What is in this issue
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Tags: What is in This Issue Source Type: research

Phosphorylated EGFR at tyrosine 1173 correlates with poor prognosis in oral squamous cell carcinomas
ConclusionEGFR is highly expressed in OSCC and is phosphorylated in more than one third of the cases. The independent value of pEGFR expression in cause‐specific survival of OSCC suggests that this marker may serve as reliable biological marker to identify high‐risk subgroups and to guide therapy.© 2013 John Wiley & Sons A/S
Source: Oral Diseases - February 17, 2013 Category: ENT & OMF Authors: Luís Silva Monteiro, Sara Ricardo, Maria Leonor Delgado, Fernanda Garcês, Barbas do Amaral, Carlos Lopes Tags: Original Article Source Type: research

Calendar of Events
Source: International Journal of Oral and Maxillofacial Surgery - February 16, 2013 Category: ENT & OMF Source Type: research

Editorial Board/Reviewing Committee
Source: International Journal of Oral and Maxillofacial Surgery - February 16, 2013 Category: ENT & OMF Source Type: research

Immunomodulatory properties of dental tissue‐derived mesenchymal stem cells
Abstract In addition to their well‐established self‐renewal and multipotent differentiation properties, mesenchymal stem cells (MSCs) also possess potent immunomodulatory functions both in vitro and in vivo, which render them a potential novel immunotherapeutic tool for a variety of autoimmune and inflammation related diseases. The major mechanisms may involve (1) the secretion of an array of soluble factors such as prostaglandin E2 (PGE2), indoleamine2, 3‐dioxygenase (IDO), transforming growth factor‐β(TGF‐β), human leukocyte antigen G5 (HLA‐G5) etc.; (2) interactions between MSCs and immune cells such as T ...
Source: Oral Diseases - February 16, 2013 Category: ENT & OMF Authors: Zheng Li, Chun‐miao Jiang, Shu An, Qian Cheng, Yi‐fan Huang, Ya‐ting Wang, Yong‐chao Gou, Lan Xiao, Wen‐jing Yu, Jun Wang Tags: Review Article Source Type: research

Comparison of antiallergic effects of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine in a murine model of allergic rhinitis
Conclusion and Clinical RelevanceBoth PV and PCV suppressed the allergen‐specific T helper 2 response and induced regulatory T cells in a murine model of allergic rhinitis. However, PV and PCV may activate Treg cells via different mechanisms. Level of EvidenceN/A. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Boo‐Young Kim, Ji‐Hyeon Shin, Hyang Rim Park, Sung Won Kim, Soo Whan Kim Tags: Allergy/Rhinology Source Type: research

Comparison of Scholarly Impact Among Surgical Specialties
Conclusionsh‐indices among the different surgical specialties vary and are potentially impacted by the number of practitioners as well as research emphasis within a field. The mean h‐index of academic otolaryngologists falls in the lower values for academic surgeons. Because this metric varies among different fields, it is most relevant for comparison when examining values within a field. H‐indices reliably increase with increasing academic rank through professor and offer a quantifiable and objective alternative to other metrics when evaluating faculty members for academic advancement. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Peter F. Svider, Anna A. Pashkova, Zaid Choudhry, Nitin Agarwal, Olga Kovalerchik, Soly Baredes, James K. Liu, Jean Anderson Eloy Tags: General Otolaryngology Source Type: research

Septal Button Insertion
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Jonathan Abbas, Shahram Anari Tags: Allergy/Rhinology Source Type: research

A Qualitative Analysis of Faculty Motivation to Participate in Otolaryngology Simulation Boot Camps
ConclusionEnjoyment of teaching; benefits to all participants; and opportunities for self‐improvement emerged as themes of faculty motivation to participate in SBBC. SBBC have unique characteristics which provide an opportunity to facilitate teaching experiences that motivate faculty. Level of Evidence5. Laryngoscope, 2012
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Ellen S. Deutsch, Alberto Orioles, Kathryn Kreicher, Kelly M. Malloy, David L. Rodgers Tags: General Otolaryngology Source Type: research

Clinical Characteristics and Prognostic Factors of Adenoid Cystic Carcinoma of the Head and Neck
ConclusionsAge, DM, tumor site, histologic grade, and stage were independently significant prognostic factors for ACCHN. In addition, an adequate dose of postoperative radiotherapy can improve local control and DFS of patients with ACCHN. Level of Evidence2b. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Yunsuk Choi, Sung‐Bae Kim, Dok Hyun Yoon, Ji Youn Kim, Sang‐wook Lee, Kyung‐Ja Cho Tags: Head and Neck Source Type: research

Evaluating Endoscopic and Endoscopic‐Assisted Access to the Infratemporal Fossa
ConclusionsThis evaluation paradigm provides useful data in evaluating an endoscopic or endoscopic‐assisted approach to the ITF. Using this paradigm, the SLT and MMA were analyzed. Each provided adequate access to the ITF, but visualization and maneuverability were better in SLT. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Anand K. Devaiah, David Reiersen, Todd Hoagland Tags: Allergy/Rhinology Source Type: research

Invasive Fungal Rhinosinusitis
ConclusionsDSS and OS remain low for patients with AIFR. Extensive surgical resection in patients with these poor prognostic signs should be considered carefully in light of their poor survival. Long‐term survivors are at significant risk of sinonasal complications and should be followed closely. Level of Evidence4. Laryngoscope, 2012
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Marcus M. Monroe, Max McLean, Nathan Sautter, Mark K. Wax, Peter E. Andersen, Timothy L. Smith, Neil D. Gross Tags: Allergy/Rhinology Source Type: research

Patterns of Care Before and After the Adult Sinusitis Clinical Practice Guideline
ConclusionsCare patterns for the medical treatment of acute adult sinusitis have changed after guideline publication, with an increase in oral antibiotic prescription rates in cases of acute sinusitis and increase in the use of amoxicillin as the first‐line antimicrobial agent. The latter is strongly in keeping with guideline recommendation. Clinicians' espousal of the analgesic recommendations likely needs improvement to better comply with guideline recommendations. Level of Evidence2b. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Neil Bhattacharyya, Lynn J. Kepnes Tags: Allergy/Rhinology Source Type: research

Multidimensional Voice Outcomes After Type I Gore‐Tex Thyroplasty in Patients With Nonparalytic Glottic Incompetence
ConclusionsRegardless of etiology, patients with nonparalytic GI demonstrated improved subjective and perceptual measures following GTP. Although showing trends toward improvement, vocal fold scar patients performed worse than all other subgroups across all three voice outcome measures. Level of Evidence4. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Rupali N. Shah, Allison M. Deal, Robert A. Buckmire Tags: Laryngology Source Type: research

Three‐Dimensional Analysis of Pharyngeal High‐Resolution Manometry Data
ConclusionThree‐dimensional analysis led to improved classification of swallows based on pharyngeal HRM. Artificial neural network performance with both two‐dimensional and three‐dimensional analyses was effective, classifying a large percentage of swallows correctly, thus demonstrating its potential clinical utility. Level of Evidence4. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Zhixian Geng, Matthew R. Hoffman, Corinne A. Jones, Timothy M. McCulloch, Jack J. Jiang Tags: Laryngology Source Type: research

Clinical Characteristics of Patients With Narrow Bony Cochlear Nerve Canal
ConclusionsNarrow bony cochlear nerve canal is not likely to have a simple Mendelian inheritance pattern, especially in unilateral cases. The contribution of a Mendelian genetic etiology to bilateral narrow bony cochlear nerve canals remains elusive. More frequent coexistence of internal auditory canal narrowing among unilateral narrow bony cochlear nerve canal cases suggests that bilateral narrow bony cochlear nerve canals are not just a duplicate of the unilateral narrow bony cochlear nerve canal. Level of Evidence4. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Sung‐Woo Cho, Seong Il Kang, Sung Joon Park, Ah Reum Kim, Ja Won Koo, Chong Sun Kim, Jun Ho Lee, Sun O Chang, Seung‐Ha Oh, Byung Yoon Choi Tags: Otology/Neurotology Source Type: research

Trends in Otolaryngologic Utilization of Computed Tomography for Sinonasal Disorders
ConclusionsDespite widespread availability of imaging and a strong prevalence of sinonasal diagnoses, otolaryngologists' CT ordering patterns have not resulted in increased utilization over the past 6 years. This suggests that otolaryngologists are remaining consistent in their ordering patterns for sinonasal CT. Level of Evidence2c. Laryngoscope, 2013
Source: The Laryngoscope - February 16, 2013 Category: ENT & OMF Authors: Neil Bhattacharyya Tags: Allergy/Rhinology Source Type: research

Evaluation of salivary biomarker profiles following non‐surgical management of chronic periodontitis
ConclusionsOur data suggest that salivary sTLR‐2 is a potential prognostic or maintenance marker for chronic periodontitis. The observed variability of salivary cytokines is consistent with the role of these cytokines in the progression of chronic periodontitis.© 2013 John Wiley & Sons A/S
Source: Oral Diseases - February 15, 2013 Category: ENT & OMF Authors: S. Prakasam, M. Srinivasan Tags: Original Article Source Type: research

Osler-Weber-Rendu syndrome simulating pulmonary metastasis
Osler–Weber–Rendu syndrome, also known as hereditary haemorrhagic telangiectasia (HHT), is an autosomal dominant disorder of abnormal blood vessel formation manifesting as telangiectasias and arteriovenous malformations (AVMs). The criteria for the diagnosis of HHT are epistaxis, multiple telangiectasias at mucocutaneous surfaces, AVMs in larger organ systems, and a family history of HHT.1–3 Recurrent epistaxis is the most common presenting complaint. Cerebral AVMs occur in about 10–20% of patients with HHT, and are associated with high mortality and morbidity due to stroke or brain abscess. MRI is ...
Source: Postgraduate Medical Journal - February 15, 2013 Category: Journals (General) Authors: Pereira e Silva, J. L., Zanetti, G., Marchiori, E. Tags: GI bleeding, Genetics, Echocardiography, Stroke, Radiology, Surgical diagnostic tests, General surgery, Radiology (diagnostics), Ear, nose and throat/otolaryngology, Epidemiology Images in medicine Source Type: research

Low/negative expression of DDX3 might predict poor prognosis in non‐smoker patients with oral cancer
ConclusionsLow/negative DDX3 expression in tumor cells was significantly associated with aggressive clinical manifestations and might be an independent survival predictor, particularly in non‐smoker patients with OSCC.
Source: Oral Diseases - February 15, 2013 Category: ENT & OMF Authors: C‐H Lee, S‐H Lin, S‐F Yang, S‐M Yang, M‐K Chen, H Lee, J‐L Ko, C‐J Chen, K‐T Yeh Tags: Original Article Source Type: research

Boron neutron capture therapy for oral precancer: proof of principle in an experimental animal model
ConclusionBNCT can be optimized for the integral treatment for head and neck cancer, considering the implications for field‐cancerized tissue.
Source: Oral Diseases - February 15, 2013 Category: ENT & OMF Authors: A Monti Hughes, ECC Pozzi, S Thorp, MA Garabalino, RO Farías, SJ González, EM Heber, ME Itoiz, RF Aromando, AJ Molinari, M Miller, DW Nigg, P Curotto, VA Trivillin, AE Schwint Tags: Original Article Source Type: research

Hydrogen peroxide alters sternohyoid muscle function
Abstract Upper airway (UA) dilator muscles are critical for the maintenance of airway patency. Injury or fatigue to this group of muscles, as observed in obstructive sleep apnoea (OSA) patients and animal models of OSA, may leave the UA susceptible to collapse. Although the mechanisms underlying respiratory muscle dysfunction are not completely understood, there is strong evidence suggesting a link between increased production of reactive oxygen species and altered muscle function. The aim of this study was to examine the effects of H2O2 on rat sternohyoid muscle function in vitro. Sternohyoid contractile and endurance pro...
Source: Oral Diseases - February 15, 2013 Category: ENT & OMF Authors: Christine M. Shortt, Ken D. O'Halloran Tags: Original Article Source Type: research

Morbidity prior to a Diagnosis of Sleep-Disordered Breathing: A Controlled National Study
Conclusions:Patients with SDB show significant morbidities several years prior to a diagnosis of OSA or OHS. OSA should be considered in all medical specialties as an important comorbidity. In our study, evidence points to particular emphasis for considering this diagnosis in endocrinology and metabolic specialties.Citation:Jennum P; Ibsen R; Kjellberg J. Morbidity prior to a diagnosis of sleep-disordered breathing: a controlled national study. J Clin Sleep Med 2013;9(2):103–108.
Source: Journal of Clinical Sleep Medicine : JCSM - February 14, 2013 Category: Sleep Medicine Source Type: research

The management of ingested foreign bodies in an Ear Nose and Throat emergency unit: Prospective study of 204 cases.
CONCLUSIONS: Patients with ingestion of foreign body who ingest fish bone, present within the first 6hours or complain of symptoms at or above cricoid cartilage deserve greater investment in terms of time and resources for retrieval of ingested foreign body by Ear Nose and Throat team. PMID: 23415608 [PubMed - as supplied by publisher]
Source: Acta Otorrinolaringologica Espanola - February 14, 2013 Category: ENT & OMF Authors: Marçal N, Soares JB, Pereira G, Guimarães J, Gonçalves M, Godinho T Tags: Acta Otorrinolaringol Esp Source Type: research

Follicular dendritic cell sarcoma of the tonsil.
PMID: 23415609 [PubMed - as supplied by publisher]
Source: Acta Otorrinolaringologica Espanola - February 14, 2013 Category: ENT & OMF Authors: Ribeiro L, Lima N, Almeida A, Condé A Tags: Acta Otorrinolaringol Esp Source Type: research

[Efficacy of a novel warming blanket : Prospective randomized trial.]
CONCLUSIONS: In the studied patient group the new conductive warming blanket (Barrier® EasyWarm®) showed no superiority compared to conventional thermal insulation alone. PMID: 23404220 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - February 14, 2013 Category: Anesthesiology Authors: Brandes IF, Müller C, Perl T, Russo SG, Bauer M, Bräuer A Tags: Anaesthesist Source Type: research

Sore throat consultations in general practice prior to tonsillectomy among eight hundred and sixty three children in England: is this in accordance with the SIGN guidelines?
KEY POINTSThe Scottish Intercollegiate Guidelines Network first published guidelines on the indications for tonsillectomy for sore throats in adults and children in 1999.These guidelines highlighted the importance of reserving the operation for those who are severely affected by recurrent sore throats and by applying the Paradise criteria.We aimed to determine if the guidelines have been adopted by general practitioners.The percentage of children aged 4‐15 years who underwent tonsillectomy who also fulfilled the The Scottish Intercollegiate Guidelines Network criteria for the minimum number of documented prior sore throa...
Source: Clinical Otolaryngology - February 14, 2013 Category: ENT & OMF Authors: Koshy Elizabeth, Curcin Vasa, Bottle Alex, Sharland Mike, Saxena Sonia Tags: Our Experience Source Type: research

Focal Dermal Hypoplasia: an updated review of the new discoveries in the last two decades
Abstract Focal dermal hypoplasia (FDH), or Goltz‐Gorlin syndrome, is a rare syndrome and may result in multisystem disorders. Several reviews of FDH have been published. However, the last comprehensive review of this disorder appeared more than 20 years ago. To date, a number of new clinical manifestations have been reported and considerable knowledge has accumulated regarding etiology and pathogenetic mechanisms. The purpose of this review is to gather this more recent data and to provide organized and reliable information. So we reviewed 159 cases of FDH which had been reported from 1990 to 2012, summarized the new dis...
Source: Oral Diseases - February 13, 2013 Category: ENT & OMF Authors: Lili Wang, Xin Jin, Xin Zhao, Dongjuan Liu, Ting Hu, Lu Jiang, Hongxia Dan, Xin Zeng, Qianming Chen Tags: Review Article Source Type: research

Modern day relevance of William Hunter's approach to teaching “The organ of hearing”
William Hunter, a pioneering teacher of Anatomy in the the eighteenth century, championed the use of dissected specimens as aids in the teaching of anatomy. Although Hunter promoted the Paris method of learning Anatomy, by student dissection, he also used prosected material as an adjunct to his lectures. We are fortunate that Hunter bequeathed his extensive collection of over 3,000 museum specimens to the University of Glasgow, many of which are housed in the Laboratory of Human Anatomy in the Thomson Building. Regions such as the temporal bone are frequently difficult for students, and indeed postgraduate trainees in ear ...
Source: Clinical Anatomy - February 13, 2013 Category: Anatomy Authors: Helena Roth, Robert A. Smith, Sarah Mackay Tags: A Glimpse of Our Past Source Type: research

Radio‐Protective Effects Of Nigella Sativa Oil On Oxidative Stress In Tongue Tissue Of Rats
ConclusionN.S. oil may be a beneficial agent in protecting against ionizing radiation‐related tissue injury.© 2013 John Wiley & Sons A/S
Source: Oral Diseases - February 12, 2013 Category: ENT & OMF Authors: Kemal Üstün, Seyithan Taysı, Ufuk Sezer, Elif Demir, Elif Baysal, Tuncer Demir, Edibe Sarıçiçek, Hilal Alkış, Suleyman Ziya Şenyurt, Mehmet Tarakçıoğlu, Nurten Aksoy Tags: Original Article Source Type: research

Are you a 'supertaster'?
About a quarter of the population has an especially sensitive sense of taste. What does it mean, and how can you find out if you're one of them?If you're passionate about an art form, be it musical, visual or culinary, it can be galling when others claim to feel your beloved medium more intensely than you. Oh please, you might silently harrumph, you can't prove that. And anyway, I can't hear a note of the Carpenters without my Adam's apple bobbing meaningfully, so bog off.But when it comes to tasting, superior sensitivity can actually be proven. A quick test could reveal you to be what sensory perception scientists refer t...
Source: Guardian Unlimited Science - February 12, 2013 Category: Science Authors: Amy Fleming Tags: Blogposts guardian.co.uk Food & drink Life and style Food science Source Type: news

Videofluoroscopic‐guided botulinum toxin injections for pharyngoesophageal spasm after total laryngectomy
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Matthew E. Spector, Elizabeth Callaway, Erin L. McKean, Mark E. Prince Tags: Head and Neck Source Type: research

The impact of treatment modality and radiation technique on outcomes and toxicity of patients with locally advanced oropharyngeal cancer
Conclusions:Compared to radiation alone, chemoradiotherapy significantly improved oncologic outcomes, but with significantly increased toxicity. Compared to 3DCRT, the introduction of IMRT resulted in a significant reduction of acute and late toxicity with slightly better, or at least comparable, outcomes. Despite the improvements achieved by the implementation of chemo‐IMRT, different new strategies to further improve outcome and reduce toxicity need to be thoroughly investigated in prospective, preferably, randomized trials.
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Abrahim Al‐Mamgani, Peter van Rooij, Gerda M. Verduijn, Robert Mehilal, Jeroen D. Kerrebijn, Peter C. Levendag Tags: Head and Neck Source Type: research

Oncocytic carcinoma of the parotid gland
Conclusions:Conservative parotidectomy is not radical enough to treat oncocytic carcinoma of the parotid gland. Elective neck dissection is recommended for patients with cancer stage T2 to 4. Surgery with postoperative 125I brachytherapy leads to good local control for patients with advanced disease or with positive or close resection margins.
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Ming‐Wei Huang, Jian‐Guo Zhang, Jie Zhang, Shu‐Ming Liu, Lei Zheng, Yan Shi, Dian‐Yin Shi, Guang‐Yan Yu Tags: Head and Neck Source Type: research

The addition of a contralateral routing of signals microphone to a unilateral cochlear implant system—A prospective study in speech outcomes
ConclusionsAdding a contralateral microphone to a unilateral CI resulted in a significant improvement in speech understanding in different conditions. This method could provide a greater cost/benefit ratio than bilateral CIs and be a potential improvement for those who are not candidates for bilateral CIs. Level of Evidence2b. Laryngoscope, 2013
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Roochi Arora, Hosam Amoodi, Suzanne Stewart, Lendra Friesen, Vincent Lin, Julian Nedzelski, Joseph Chen Tags: Otology/Neurotology Source Type: research

Assessment of fine needle aspiration feasibility and specimen adequacy for molecular diagnostics of benign vocal fold lesions
ConclusionsFNA of the vocal fold lamina propria is technically feasible to perform. Further improvement in the FNA technology is desirable to optimize RNA quality for reliable gene expression analysis.
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Nicole Y. K. Li, Seth Dailey, Susan L. Thibeault Tags: Laryngology Source Type: research

First stage in predicative measure for transnasal transsphenoidal approach to petrous apex cholesterol granuloma
ConclusionsNormative data on consistent petrous apex radiographic landmarks are important for assessing the feasibility of the transphenoidal approach to the petrous apex for cholesterol granuloma drainage. Based on a large population of normal computed tomography scans, the majority of temporal bones (82.8%) have a petrous angle ranging between 10.0 and 20.0 degrees.
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Neal Shoman, Angela M. Donaldson, Jeffrey Ksiazek, Myles L. Pensak, Lee A. Zimmer Tags: Cranial Base Source Type: research

Prevalence of clarithromycin‐resistant Helicobacter pylori in patients with chronic tonsillitis by allele‐specific scorpion real‐time polymerase chain reaction assay
ConclusionsThe reported rate of resistance to clarithromycin is of great variation among H. pylori strains isolated from specimens in different countries. Our study showed that the most prevalent genotypes in our H. pylori‐positive specimens was A2142G followed by A2143G, which is different from reported results of allele‐specific genotyping of H. pylori strains isolated from gastric biopsy and may be a result of cross‐resistance to erythromycin and other macrolides.
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Taghi Naserpour Farivar, Reza Najafipour, Pouran Johari Tags: Laryngology Source Type: research

Computer‐assisted assessment of ocular synkinesis: A comparison of methods
ConclusionsThe Facial Assessment by Computer Evaluation program yields rapid, consistent, palpebral fissure width measurements, and when combined with a subjective self‐assessment questionnaire yields a comprehensive measure of ocular synkinesis. Our modified application of the Glasgow Facial Palsy Scale did not appear to be a reliable method for quantitative ocular synkinesis assessment. Level of Evidence3b Laryngoscope, 2013
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: Ingrid J. Kleiss, Marc H. Hohman, Olivia E. Quatela, Henri A. M. Marres, Tessa A. Hadlock Tags: Facial Plastics and Reconstructive Surgery Source Type: research

Predicting positive margins in resection of cutaneous melanoma of the head and neck
ConclusionsIn this large series of head and neck melanomas excised using National Comprehensive Cancer Network–recommended margins, histopathologic margin status could be predicted based on age but not on lesion characteristics. This finding is surprising given the published data showing that melanoma in situ has a higher rate of positive margin compared to subtypes of invasive melanoma. It reinforces the need for delaying reconstruction until margins are clear or performing reconstruction at a time of resection that does not compromise the ability to resect margins further (e.g., skin graft). Level of Evidence2c Laryngoscope, 2013
Source: The Laryngoscope - February 12, 2013 Category: ENT & OMF Authors: J. Jared Christophel, Andrew K. Johnson, Timothy L. McMurry, Stephen S. Park, Paul A. Levine Tags: Head and Neck Source Type: research