Endocrinology This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the most recent publications within this specialty of the MedWorm directory.

Thyroid consensuses: guidelines for clinical practice
(Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

Highlights of the new consensuses on thyroid diseases of the Brazilian Society of Endocrinology and Metabolism
(Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

The Brazilian consensus for the clinical approach and treatment of subclinical hypothyroidism in adults: recommendations of the thyroid Department of the Brazilian Society of Endocrinology and Metabolism
CONCLUSION: Treatment with levothyroxine was recommended for all patients with persistent SCH with serum TSH values > 10 mU/L and for certain patient subgroups. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

Congenital hypothyroidism: recommendations of the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism
O hipotireoidismo congênito (HC) é o distúrbio endócrino congênito mais frequente, com incidência variando de 1:2.000 a 1:4.000 crianças nascidas vivas e uma das principais causas de retardo mental que pode ser prevenida. Os Programas de Triagem Neonatal para a doença permitem a identificação precoce dos afetados e seu tratamento de modo a evitar as complicações da falta do hormônio. A maioria dos casos de hipotireoidismo congênito é decorrente de disgenesias tireoidianas (85%), entre elas a ectopia, hipoplasia ou agenesia tireoidianas, e os demais resultam de defeitos de síntese hormonal. As crianças afet...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

The clinical use of thyroid function tests
The objective of this article is to do a critical analysis of the appropriate use of the most important thyroid function tests, including serum concentrations of thyrotropin (TSH), thyroid hormones and antithyroid antibodies. Through a survey in the MedLine database, we discuss the major pitfalls and interferences related to daily use of these tests and recommendations are presented to optimize the use of these diagnostic tools in clinical practice. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

The Brazilian consensus for the diagnosis and treatment of hyperthyroidism: recommendations by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism
CONCLUSIONS: The clinical diagnosis of hyperthyroidism usually offers no difficulty and should be made with measurements of serum TSH and thyroid hormones. The treatment can be performed with antithyroid drugs, surgery or administration of radioactive iodine according to the etiology of thyrotoxicosis, local availability of methods and preferences of the attending physician and patient. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

Contributors
(Source: Endocrinology and Metabolism Clinics of North America)
Source: Endocrinology and Metabolism Clinics of North America - May 24, 2013 Category: Endocrinology Source Type: research

Contents
(Source: Endocrinology and Metabolism Clinics of North America)
Source: Endocrinology and Metabolism Clinics of North America - May 24, 2013 Category: Endocrinology Source Type: research

Forthcoming Issues
(Source: Endocrinology and Metabolism Clinics of North America)
Source: Endocrinology and Metabolism Clinics of North America - May 24, 2013 Category: Endocrinology Source Type: research

Frailty, Sarcopenia, and Hormones
Frailty is now a definable clinical syndrome with a simple screening test. Age-related changes in hormones play a major role in the development of frailty by reducing muscle mass and strength (sarcopenia). Selective Androgen Receptor Molecules and ghrelin agonists are being developed to treat sarcopenia. The role of Activin Type IIB soluble receptors and Follistatin-like 3 mimetics is less certain because of side effects. Exercise (resistance and aerobic), vitamin D and protein supplementation, and reduction of polypharmacy are keys to the treatment of frailty. (Source: Endocrinology and Metabolism Clinics of North America)
Source: Endocrinology and Metabolism Clinics of North America - May 24, 2013 Category: Endocrinology Authors: John E. Morley, Theodore K. Malmstrom Source Type: research

Index
(Source: Endocrinology and Metabolism Clinics of North America)
Source: Endocrinology and Metabolism Clinics of North America - May 24, 2013 Category: Endocrinology Source Type: research

microRNAs regulate adipocyte differentiation.
Abstract The number of adipocytes is relevant to the extent of differentiation from pluripotent stem cells into pre-adipocytes, whereas the size of adipocytes relates to the extent of differentiation from pre-adipocytes into mature fat cells and the accumulation of triglyceride. Investigation of the molecular regulatory mechanism of adipocyte differentiation is not only essential for understanding the physiological processes of adipogenesis, but it is also important for identifying new biomarkers and therapeutic targets for some metabolic diseases, such as obesity and diabetes. microRNAs (miRNAs) appear to play imp...
Source: Cell Biology International - May 24, 2013 Category: Cytology Authors: Chen L, Song J, Cui J, Hou J, Zheng X, Li C, Liu L Tags: Cell Biol Int Source Type: research

Induced autologous stem cell transplantation for treatment of rabbit type 1 diabetes.
In conclusion, treatment with induced multipotent stem cells can reduce blood sugar levels, improve islet cell function, and repair damaged pancreas in a rabbit model of type 1 diabetes. PMID: 23483723 [PubMed - in process] (Source: Cell Biology International)
Source: Cell Biology International - May 24, 2013 Category: Cytology Authors: Hu MJ, Ruan GP, Yao X, Ruan GH, Wang JX, Pang RQ, Cai XM, Zhu XQ, He J, Pan XH Tags: Cell Biol Int Source Type: research

Some statins 'raise diabetes risk'
Some drugs taken to protect the heart may increase the risk of developing Type-2 diabetes, according to researchers in Canada. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 24, 2013 Category: Consumer Health News Source Type: news

Effectiveness of topical maxacalcitol for acquired perforating disorder
We report the case of a 69-year-old Japanese woman with numerous pruritic eruptions on her trunk, arms, and legs that had existed for 5 months. She had had diabetes mellitus for 20 years and had received hemodialysis for renal failure 2 months prior to her presentation. On examination, multiple erythematous and umbilicated papules with a central keratotic plug, 3 to 5 mm in diameter, were scattered on the trunk and extremities (, A). Histopathologic examination revealed crusts containing keratin, neutrophil debris, and degenerated basophilic collagen fibers in the center of the acanthotic epidermis, an appearance consisten...
Source: Journal of the American Academy of Dermatology - May 24, 2013 Category: Dermatology Authors: Hiroyuki Yoshiya, Ryuhei Okuyama, Hisashi Uhara Tags: JAAD Online Source Type: research

Tumor necrosis factor inhibition and glucose homeostasis
We report the development of hyperglycemia related to adalimumab therapy in a patient with psoriasis. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - May 24, 2013 Category: Dermatology Authors: Ammon J. Larsen, Jennie T. Clarke Tags: JAAD Online Source Type: research

The role of insulin-like growth factor I and hypoxia inducible factor 1α in vascular endothelial growth factor expression in type 2 diabetes.
CONCLUSIONS: Our data demonstrate that HIF-1α and IL-6 could regulate VEGF expression, and that higher levels of HIF-1α, IL-6, and VEGF may contribute to the pathogenesis of diabetic micro-angiopathy. PMID: 23462604 [PubMed - in process] (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - May 23, 2013 Category: Laboratory Medicine Authors: Jiang F, Tang YT, Guo L, Jiao XY Tags: Ann Clin Lab Sci Source Type: research

Statin diabetes link
New research shows certain statins may increase diabetes risk among older people (Source: BHF National News)
Source: BHF National News - May 23, 2013 Category: Cardiology Source Type: news

Two studies address diabetes risks with statins—one good news, one so-so
While one study is reassuring for older patients treated with statins, with researchers finding no evidence of an increased risk of diabetes in acute coronary syndrome patients, the other suggests that the more potent statins, such as rosuvastatin, atorvastatin, and simvastatin, do pose an increased risk compared with pravastatin. (Source: theHeart.org)
Source: theHeart.org - May 23, 2013 Category: Cardiology Source Type: news

GRADE Trial to Compare Top Diabetes Drugs
(MedPage Today) -- Researchers are launching a large-scale comparative effectiveness trial that will help determine which of the top type 2 diabetes drugs are best for glycemic control. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 23, 2013 Category: Cardiology Source Type: news

FDA Approves AIC Test to Diagnose DiabetesFDA Approves AIC Test to Diagnose Diabetes
FDA Approvals (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 23, 2013 Category: Consumer Health News Tags: Diabetes & Endocrinology News Alert Source Type: news

Marijuana: The next diabetes drug?
Toking up may help marijuana users to stay slim and lower their risk of developing diabetes, according to the latest study, which suggests that cannabis compounds may help in controlling blood sugar. (Source: CNN.com - Health)
Source: CNN.com - Health - May 23, 2013 Category: Consumer Health News Source Type: news

Hypothyroidism Hikes Death Risk in Blacks (CME/CE)
(MedPage Today) -- African Americans with hypothyroidism face an increased risk of death, and in patients with congestive heart failure, even mild underactive thyroid disease raises mortality risk, a retrospective cohort study found. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - May 23, 2013 Category: Endocrinology Source Type: news

Marijuana tied to better blood sugar control
NEW YORK (Reuters Health) - People who had used marijuana in the past month had smaller waists and lower levels of insulin resistance - a diabetes precursor - than those who never tried the drug, in a new study. (Source: Reuters: Health)
Source: Reuters: Health - May 23, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

FDA allows marketing of first A1c test labeled for diagnosing diabetes
Today the U.S. Food and Drug Administration announced that it is allowing marketing of the COBAS INTEGRA 800 Tina-quant HbA1cDx assay (Tina-quant HbA1cDx assay) for the diagnosis of diabetes by health care professionals. This is the first HbA1c test that FDA has allowed to be marketed for this use. (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 23, 2013 Category: American Health Source Type: news

TODAY Study Sounds Alarm Bell for Youth with Type 2 DiabetesTODAY Study Sounds Alarm Bell for Youth with Type 2 Diabetes
Youths with an aggressive form of type 2 diabetes may have complications such as kidney and cardiovascular disease as early as their 20s and 30s, new data from the TODAY study suggest. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 23, 2013 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Fish body oil may reduce risk of type 2 diabetes
BOSTON, May 23 (UPI) -- Fish body oil supplements modestly increase amounts of a hormone associated with lower risk of type 2 diabetes and heart disease, U.S. researchers say. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 23, 2013 Category: Consumer Health News Source Type: news

Diabetes Drug Shows Promise in Parkinson'sDiabetes Drug Shows Promise in Parkinson's
Results of small proof-of-concept trial should spur further interest in funding a larger controlled trial of exenatide in patients with PD. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 23, 2013 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Trans Fats Still Sneaking into Food Supply (CME/CE)
(MedPage Today) -- With the growing focus on the ill effects of trans-fatty acids, the majority of food companies have lowered levels of the ingredient in their products -- but only about half completely eliminated use of the processed fat, researchers found. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - May 23, 2013 Category: Endocrinology Source Type: news

A National Web Conference on Using Health IT To Improve Outcomes in Vulnerable and Disadvantaged Populations
Date: June 3, 2013 Time: 10:30a.m-12:00 p.m., PST Overall Purpose: The Agency for Healthcare Research and Quality (AHRQ) has identified a gap in health care and public health practitioners’ knowledge of health IT using multiple mechanisms, including the findings of the continuing education (CE) planning group. This series of Webinars is designed to increase practitioners’ ability to improve health care decisionmaking, support patient-centered care, and improve the quality and safety of care through the use of health IT. Health IT can enhance self-management and quality of life for patients within traditionally vulnera...
Source: Dragonfly - May 23, 2013 Category: Databases & Libraries Authors: Mahria Lebow Tags: Public Health Technology Source Type: news

High tumor necrosis factor-α/interleukin-10 ratio is associated with hepatocellular carcinoma in patients with chronic hepatitis C.
Abstract Hepatitis C virus (HCV) is the main cause of chronic liver disease, cirrhosis and hepatocellular carcinoma (HCC) worldwide. The risk for the development of HCC increases with the severity of liver inflammation and fibrosis. The hepatic inflammation caused by HCV involves host regulatory immune response, which is mediated by cytokines with anti-viral role upon the interaction of viral polypeptides with innate and adaptive immunity. Two cytokines; tumor necrosis factor-α (TNF-α) and interleukin-10 (IL-10) play key roles in the regulation of cellular immune response in HCV infection. The aim of the present ...
Source: Cytokine - May 23, 2013 Category: Molecular Biology Authors: Aroucha DC, do Carmo RF, Moura P, Silva JL, Vasconcelos LR, Cavalcanti MS, Muniz MT, Aroucha ML, Siqueira ER, Cahú GG, Pereira LM, Coêlho MR Tags: Cytokine Source Type: research

Self-antigen expression in thymic epithelial cells in Ifn-γ or Tnf-α deficiency.
The objective of this study was to examine the physiological role of these cytokines in vivo. For this purpose, we examined whether these cytokines have a physiological role in regulating thymic insulin expression using the Ifn-γ and Tnf-α knockout models. We found that insulin expression increased in the knockout mice compared to their wild-type counterparts. Aire transcriptional regulator, a known switch for self-antigen expression in the thymus, was also increased in the knockout animals. Four antigens targeted in other autoimmune disorders were also found to have a pattern of increase in the Ifn-γ or Tnf-α knockout...
Source: Cytokine - May 23, 2013 Category: Molecular Biology Authors: Levi D, Polychronakos C Tags: Cytokine Source Type: research

Erythropoietin Receptor (EpoR) Agonism Is Used to Treat a Wide Range of Disease.
Abstract The erythropoietin receptor (EpoR) was discovered and described in red blood cells (RBCs), stimulating its proliferation and survival. The target in humans for EpoR agonists drugs appears clear-to treat anemia. However, there is evidence of the pleitropic actions of erythropoietin (Epo). For that reason, rhEpo therapy was suggested as a reliable approach for treating a broad range of pathologies, including heart and cardiovascular diseases, neurodegenerative disorders (Parkinson's and Alzheimer's disease), spinal cord injury, stroke, diabetic retinopathy and rare diseases (Friedreich ataxia). Unfortunately...
Source: Molecular Medicine - May 23, 2013 Category: Molecular Biology Authors: Sanchis-Gomar F, Perez-Quilis C, Lippi G Tags: Mol Med Source Type: research

Enhancement of wound closure in diabetic mice by ex vivo expanded cord blood CD34(+) cells.
This study aimed to investigate the influence on wound closure of treatments using expanded human cord blood CD34(+) cells (CB-CD34(+) cells), freshly isolated CB-CD34(+) cells and a cytokine cocktail. The test subjects were mice with streptozotocin-induced diabetes. Wounds treated with fresh CB-CD34(+) cells showed more rapid repair than mice given the PBS control. Injection of expanded CB-CD34(+) cells improved wound closure significantly, whereas the injection of the cytokine cocktail alone did not improve wound repair. The results also demonstrated a significant decrease in epithelial gaps and advanced re-epithelializa...
Source: Cellular and Molecular Biology Letters - May 23, 2013 Category: Biochemistry Authors: Chotinantakul K, Dechsukhum C, Dejjuy D, Leeanansaksiri W Tags: Cell Mol Biol Lett Source Type: research

Total Arterial Coronary Artery Bypass Grafting in Patients with Diabetes
Introduction: Coronary artery bypass grafting using arterial conduits may improve survival and minimise harvest site complications. However, in diabetes, the outcomes of coronary artery bypass grafting performed exclusively using arterial conduits are uncertain. We reviewed our experience with this approach. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - May 23, 2013 Category: Cardiology Authors: Sean D. Galvin, William Y. Shi, John A. Fuller, Philip A. Hayward, Brian F. Buxton Tags: Abstracts Source Type: research

The Role of Closure Techniques in Sternal Dehiscence – An Artificial Model
Introduction: Sternal wound complications are a cause of significant post-operative morbidity and mortality and are generally more common in patients undergoing cardiac surgery who are elderly, have severe COPD, osteoporosis, diabetes or are undergoing bilateral mammary harvest . Many surgeons have a preferred method of sternal closure and it has been suggested that how the sternum is closed may affect the risk of dehiscence . This project was aimed at developing an artificial model of sternal dehiscence, given the difficulties of procuring cadaveric sternums and to see if there was a difference in dehiscence between the t...
Source: Heart, Lung and Circulation - May 23, 2013 Category: Cardiology Authors: Felicity Meikle, Sean Galvin, Yuanji Zhang, Kim Pickering, Adam El-Gamel Tags: Abstracts Source Type: research

High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia.
We examined the relationship of these bacteria and their resistance mechanisms to the diabetic disease status of patients in Saudi Arabia. Susceptibilities of 271 isolates to carbapenems, tigecycline and colistin were determined, followed by detection of carbapenemase genes. A blaVIM gene was detected in ~95 % of isolates; blaOXA-23 and blaOXA-40 genes were also prevalent. Diabetic patients were significantly more likely to carry carbapenem-resistant isolates. Carbapenem-resistant A. baumannii is a serious problem in diabetic patients, and molecular detection of resistance mechanisms in these isolates is required. PM...
Source: Journal of Medical Microbiology - May 23, 2013 Category: Microbiology Authors: Alsultan AA, Evans BA, Elsayed EA, Al-Thawadi SI, Al-Taher AY, Amyes SG, Al-Dughaym AM, Hamouda A Tags: J Med Microbiol Source Type: research