Gastroenterology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 17.
Updates to UK DUETS
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The latest update to the Cochrane Database of Systematic Reviews (Issue 4, 2009) provided 25 new uncertainties to add to the UK DUETS database. Follow the link for details.
Source: Gastroenterology and Liver Diseases Specialist Library - Oesophagus - October 17, 2009 Category: Gastroenterology Source Type: organizations
Risk of pancreatic cancer in chronic hepatitis B virus infection: data from the REVEAL-HBV cohort studyEmail this article to a colleague.
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The relationship between the hepatitis B virus (HBV) and pancreatic cancer remains unclear. Because HBV has been isolated from pancreatic tissue, we hypothesized that HBV may play a role in the development of pancreatic carcinoma. This cohort was recruited between 1991 and 1992. Serum samples obtained at enrolment were tested for HBsAg and HBeAg by radioimmunoassay. Pancreatic cancer diagnosis was ascertained through data linkage with profiles of the National Cancer Registry and Death Certification System in Taiwan from 1 January 1991 to 31 December 2007. Multivariate-adjusted hazards ratios (HRadj) with 95% confidence int...
Source: Liver International - October 16, 2009 Category: Gastroenterology Authors: Uchenna H. Iloeje, Hwai-I Yang, Chin-Lan Jen, Jun Su, Li-Yu Wang, San-Lin You, Sheng-Nan Lu, Chien-Jen Chen Source Type: journals
Gut Bacteria Linked to Immune Response (CME/CE)Email this article to a colleague.
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Specific bacteria in the gut may stimulate the immune system (MedPage Today) -- helping to fight infection in some cases, but perhaps also playing a role in autoimmune disease, researchers said.
Source: MedPage Today Gastroenterology - October 16, 2009 Category: Gastroenterology Source Type: news
Updates to UK DUETSEmail this article to a colleague.
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The latest update to the Cochrane Database of Systematic Reviews (Issue 4, 2009) provided 25 new uncertainties to add to the UK DUETS database. Follow the link for details.
Source: Gastroenterology and Liver Diseases Specialist Library - Common clinical problems - October 16, 2009 Category: Gastroenterology Source Type: organizations
Gastroenterology - Clinical Challenges in Primary CareEmail this article to a colleague.
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A one-day seminar looking at the key challenges for GPs – an opportunity to expand your skills in diagnosis and management
Source: NLH - Gastroenterology & Liver Diseases - Events - October 16, 2009 Category: Gastroenterology Source Type: events
Two indices accurately, noninvasively assess UC disease activityEmail this article to a colleague.
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Researchers have identified two clinical indices that they say are “valid, reliable and responsive” ways to noninvasively assess disease activity in ulcerative colitis patients.
Source: MedWire News - Gastroenterology - October 16, 2009 Category: Gastroenterology Source Type: news
Association of MicroRNA-196a-2 Gene Polymorphism with Gastric Cancer Risk in a Chinese PopulationEmail this article to a colleague.
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Conclusions These findings suggest that the genetic variant within miR-196a-2 could play an important role in the development and progression
of gastric cancer. We expect the findings may be helpful to better understand the mechanism of gastric carcinogenesis.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-009-1007-xAuthors
Sheng Peng, The Fourth Affiliated Hospital of Soochow University Department of Anesthesiology 214062 Wuxi People’s Republic of ChinaZhongshen Kuang, Shihezi University Intensive Care Unit of the First Affiliated Hospital of Medical College 832008 Shihezi P...
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
Proton Pump Inhibitor Therapy Does Not Affect Hydrogen Production on Lactulose Breath Test in Subjects with IBSEmail this article to a colleague.
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Conclusion PPI therapy does not effect hydrogen production on lactulose breath tests in IBS patients. However, there may be an effect
on methane.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-009-1010-2Authors
David Law, GI Motility Program, Cedars-Sinai Medical Center 8730 Alden Drive, Suite 225E Los Angeles CA 90048 USAMark Pimentel, GI Motility Program, Cedars-Sinai Medical Center 8730 Alden Drive, Suite 225E Los Angeles CA 90048 USA
Journal Digestive Diseases and SciencesOnline ISSN 1573-2568Print ISSN 0163-2116
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
Circulating Cytokines Reflect Mucosal Inflammatory Status in Patients with Crohn’s DiseaseEmail this article to a colleague.
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Conclusion Serum cytokine levels are excellent predictors of endoscopic activity in patients with CD.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-009-1016-9Authors
Farid Ljuca, University of Tuzla Faculty of Medicine Univerzitetska 1 Tuzla Bosnia and HerzegovinaAdnan Gegic, University Clinical Center Tuzla Department of Gastroenterology, Internal Medicine Hospital Trnovac bb 75000 Tuzla Bosnia and HerzegovinaNermin N. Salkic, University Clinical Center Tuzla Department of Gastroenterology, Internal Medicine Hospital Trnovac bb 75000 Tuzla Bosnia and HerzegovinaNada Pavlovic-C...
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
Bacterial Translocation to Mesenteric Lymph Nodes Increases in Chronic Portal Hypertensive RatsEmail this article to a colleague.
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Conclusions The enlargement of the stenosed portal tract related to triple partial portal vein ligation in the rat, since it increases
the resistance to the portal blood flow, may be a key factor involved in one of the pathological consequences of portal hypertension,
as is bacterial translocation to mesenteric lymph nodes.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-009-1001-3Authors
Miguel-Ángel Llamas, Complutense University of Madrid Microbiology Department, Biology School Madrid SpainMaría-Ángeles Aller, Complutense University of Madrid Surgery I Department, Medicin...
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
Safety and Efficacy of Total-Dose Infusion of Low Molecular Weight Iron Dextran for Iron Deficiency Anemia in Patients with Inflammatory Bowel DiseaseEmail this article to a colleague.
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Conclusion Total parenteral iron replacement with LMW iron dextran is an easy, safe, and effective alternative method for treating iron
deficiency anemia in IBD. Harmless adverse reactions may develop in a minority of patients.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-009-1022-yAuthors
Ioannis E. Koutroubakis, University Hospital Heraklion Department of Gastroenterology P.O. Box 1352 71110 Heraklion, Crete GreecePantelis Oustamanolakis, University Hospital Heraklion Department of Gastroenterology P.O. Box 1352 71110 Heraklion, Crete GreeceChristos Karakoidas, Evangelismos...
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
A Prospective Randomized Study on Computed Virtual Chromoendoscopy Versus Conventional Colonoscopy for the Detection of Small Colorectal AdenomasEmail this article to a colleague.
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Conclusions Colonoscopy with the CVC mode identified more patients with small colorectal adenomas than conventional white-light colonoscopy.
Therefore, CVC might be a supplementary tool aiding the colonoscopist in the detection of small adenomas; however, further
studies will need to demonstrate whether these results are reproducible across patients in varied clinical settings.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-009-1003-1Authors
Jae Myung Cha, East–West Neo Medical Center Department of Internal Medicine, Kyunghee University College of Medicine 149 Sangil-dong Ga...
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
A Prospective Assessment of Renal Impairment After Preparation for Colonoscopy: Oral Sodium Phosphate Appears to Be Safe in Well-Hydrated Subjects with Normal Renal StatusEmail this article to a colleague.
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Conclusions Renal failure was not detected after the use of OSPS for colonoscopy preparation in subjects with recently documented normal
renal function who were able to consume the required amounts of water after each dose. However, based on the number of subjects
studied, the theoretical risk of this complication is still between 0 and 6.3%. Thus, it is appreciated that only a very large
prospective trial would have yielded a more accurate estimate of the likelihood of renal compromise after OSPS. Despite this
caveat, OSPS has advantages over PEG in terms of the adequacy of colonic visualization and the num...
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
Consensus Guidelines in the Management of Branch Duct Intraductal Papillary Mucinous Neoplasm: A Cost-Effectiveness AnalysisEmail this article to a colleague.
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Conclusions Immediate surgery is the most effective, but may be prohibitively expensive. The surveillance strategy is a cost-effective
option compared to no surveillance.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10620-009-1014-yAuthors
Edward S. Huang, Massachusetts General Hospital Gastrointestinal Unit 101 Merrimac Street 10th Floor Boston MA 02114 USAG. Scott Gazelle, Massachusetts General Hospital Department of Radiology Boston MA USAChin Hur, Massachusetts General Hospital Gastrointestinal Unit 101 Merrimac Street 10th Floor Boston MA 02114 USA
Journal Digestive Dis...
Source: Digestive Diseases and Sciences - October 16, 2009 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: journals
Health Tip: Help Prevent StrokeEmail this article to a colleague.
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Title: Health Tip: Help Prevent StrokeCategory: Health NewsCreated: 10/16/2009 8:10:00 AMLast Editorial Review: 10/16/2009
Source: MedicineNet Crohn's Disease General - October 16, 2009 Category: Gastroenterology Source Type: consumer
National oesophago-gastric cancer audit 2009Email this article to a colleague.
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Source: NHS Evidence - Gastroenterology and liver diseases - News - October 16, 2009 Category: Gastroenterology Source Type: organizations
Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort studyEmail this article to a colleague.
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Source: NHS Evidence - Gastroenterology and liver diseases - News - October 16, 2009 Category: Gastroenterology Source Type: organizations
Latest updates to UK DUETSEmail this article to a colleague.
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Source: NHS Evidence - Gastroenterology and liver diseases - News - October 16, 2009 Category: Gastroenterology Source Type: organizations
The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancerEmail this article to a colleague.
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Conclusions:
Our data suggested that the VEGF-634G>C SNP may be a marker for susceptibility to gastric cancer, and this finding needs to be validated in larger studies.
Source: BMC Gastroenterology - October 15, 2009 Category: Gastroenterology Authors: Xiaoxiang GuanHui ZhaoJiangong NiuDongfeng TanJaffer AjaniQingyi Wei Source Type: journals
Decrease in nerve fibre density in human sigmoid colon circular muscle occurs with growth but not agingEmail this article to a colleague.
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Conclusions & Inferences In human sigmoid colon circular muscle, there are reductions in nNOS-, VIP- and SP-IR nerve fibre density with growth from newborn to late adolescence but little further change with aging. The reduction in nerve density is due to an increase in circular muscle thickness rather than a loss of nerve fibres.
Source: Neurogastroenterology and Motility - October 15, 2009 Category: Gastroenterology Authors: b. r. southwell, t. l. koh, s. q. wong, s. k. king, s.-y. ong, m. lee, p. j. farmer, c. j. peck, j. r. sutcliffe, m. p. stanton, j. keck, d. j. cook, c. w. chow, j. m. hutson Source Type: journals
TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's diseaseEmail this article to a colleague.
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Tumor necrosis factor (TNF)-like protein 1A (TL1A) is a member of the TNF superfamily and contributes to the pathogenesis of Crohn's disease (CD) by stimulating T-helper (Th) 1 cells. In addition to Th1, recent studies have focused on the role of Th17 cells in the pathogenesis of CD. Here we tried to clarify the role of TL1A in Th1 and Th17 immunity in CD.TL1A expression was assessed by quantitative reverse-transcription polymerase chain reaction (RT-PCR) in lamina propria (LP) macrophages (LP-M[phis]s) from normal controls (NC) and patients with CD or ulcerative colitis (UC). Purified LP CD4+ T cells were stimulated with ...
Source: Inflammatory Bowel Diseases - October 15, 2009 Category: Gastroenterology Authors: Nobuhiko Kamada, Tadakazu Hisamatsu, Haruki Honda, Taku Kobayashi, Hiroshi Chinen, Tetsuro Takayama, Mina T. Kitazume, Susumu Okamoto, Kazutaka Koganei, Akira Sugita, Takanori Kanai, Toshifumi Hibi Source Type: journals
Importance of duodenal bulb biopsies in children for diagnosis of celiac disease in clinical practiceEmail this article to a colleague.
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Conclusion:
The lesion in celiac disease in children can be patchy with duodenal bulb mucosa being the only area showing histological changes. The recommendations regarding the site of biopsies should be revised to include biopsies not only from distal duodenum but also from bulb to improve the diagnostic yield.
Source: BMC Gastroenterology - October 15, 2009 Category: Gastroenterology Authors: Mohsin RashidAndrea MacDonald Source Type: journals
Double-stranded RNA-activated protein kinase inhibits hepatitis C virus replication but may be not essential in interferon treatmentEmail this article to a colleague.
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Double-stranded RNA-activated protein kinase (PKR), an interferon (IFN)-stimulated gene, is activated by binding with double-stranded RNA, a putative replicative intermediate of the hepatitis C virus (HCV). Activated PKR phosphorylates the [alpha] subunit of eukaryotic initiation factor-2 to inhibit the translation of viral protein. We established stable PKR knockdown Huh7 cells using RNA interference and investigated the effect of PKR against HCV replication using a subgenomic replicon that expressed luciferase reporter protein and the JFH1 full-length HCV genome. In stable PKR knockdown cells that harboured a subgenomic ...
Source: Liver International - October 15, 2009 Category: Gastroenterology Authors: Jin-Hai Chang, Naoya Kato, Ryosuke Muroyama, Hiroyoshi Taniguchi, Bayasi Guleng, Narayan Dharel, Run-Xuan Shao, Keisuke Tateishi, Amarsanaa Jazag, Takao Kawabe, Masao Omata Source Type: journals
A curvilinear lesion arising from the right lobe of liverEmail this article to a colleague.
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Source: Liver International - October 15, 2009 Category: Gastroenterology Authors: Nitin Ghonge, Bharat Aggarwal Source Type: journals
Antibiotic therapy for Shigella dysenteryEmail this article to a colleague.
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Source: Cochrane Library
Area: Evidence > Disease Focused Reviews
Background Shigella dysentery is a relatively common illness and occasionally causes death, worldwide. Mild symptoms are self-limiting but in more severe cases, antibiotics are recommended for cure and preventing relapse. The antibiotics recommended are diverse, have regional differences in sensitivity, and have side effects.
Objectives To evaluate the efficacy and safety of antibiotics for treating Shigella dysentery.
Search strategy In June 2009 we identified all relevant trials from the following databases: Cochrane Infectious Dis...
Source: NeLM - Gastroenterology - October 15, 2009 Category: Gastroenterology Source Type: organizations
Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative dataEmail this article to a colleague.
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Conclusion:
Ontario has one of the highest rates of childhood-onset IBD in the world, and there is an accelerated increase in incidence in younger children.
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Benchimol, E I, Guttmann, A, Griffiths, A M, Rabeneck, L, Mack, D R, Brill, H, Howard, J, Guan, J, To, T Tags: Endoscopy, Colon cancer Inflammatory bowel disease Source Type: journals
Modelling dysplasia detection in ulcerative colitis: clinical implications of surveillance intensityEmail this article to a colleague.
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Conclusions:
Random biopsy surveillance is sufficiently sensitive to detect large dysplastic fields with significant colorectal cancer risk. Enhanced endoscopy can detect much smaller dysplastic fields, but these have unknown (perhaps much lower) colorectal cancer risk. Small dysplastic fields should not be assumed to indicate a high colorectal cancer risk that warrants colectomy. Prospective studies are needed to define the colorectal cancer risk and optimal management of small dysplastic lesions.
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Awais, D, Siegel, C A, Higgins, P D R Tags: Ulcerative colitis, Colon cancer Colorectal cancer Source Type: journals
Standard steroid treatment for autoimmune pancreatitisEmail this article to a colleague.
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Conclusions:
The major indication for steroid treatment in AIP is the presence of symptoms. An initial prednisolone dose of 0.6 mg/kg/day, is recommend, which is then reduced to a maintenance dose over a period of 3–6 months. Maintenance treatment with low-dose steroid reduces but dose not eliminate relapses.
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Kamisawa, T, Shimosegawa, T, Okazaki, K, Nishino, T, Watanabe, H, Kanno, A, Okumura, F, Nishikawa, T, Kobayashi, K, Ichiya, T, Takatori, H, Yamakita, K, Kubota, K, Hamano, H, Okamura, K, Hirano, K, Ito, T, Ko, S B H, Omata, M Tags: Pancreas and biliary tract, Pancreatitis Source Type: journals
Intracapillary leucocyte accumulation as a novel antihaemorrhagic mechanism in acute pancreatitis in miceEmail this article to a colleague.
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Conclusions:
ILA represents a novel protective and potentially lifesaving mechanism of haemostasis in acute pancreatitis. This process depends on expression of LFA-1 and ICAM-1 and precedes the classical steps of the leucocyte recruitment cascade.
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Ryschich, E, Kerkadze, V, Deduchovas, O, Salnikova, O, Parseliunas, A, Marten, A, Hartwig, W, Sperandio, M, Schmidt, J Tags: Pancreas and biliary tract, Pancreatitis Source Type: journals
Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in ratsEmail this article to a colleague.
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Conclusions:
Celecoxib shows a proapoptotic effect on HSCs through Akt inactivation and shows antifibrogenic effects in BDL- and TAA-treated rats, suggesting celecoxib as a novel antifibrotic agent of hepatic fibrosis.
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Paik, Y-H, Kim, J K, Lee, J I, Kang, S H, Kim, D Y, An, S H, Lee, S J, Lee, D K, Han, K-H, Chon, C Y, Lee, S I, Lee, K S, Brenner, D A Tags: Cirrhosis, Pancreas and biliary tract Hepatology Source Type: journals
Hepatitis B virus protein preS2 potentially promotes HCC development via its transcriptional activation of hTERTEmail this article to a colleague.
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Conclusions:
HBV protein preS2 upregulates hTERT via the PRR element in promoting HCC development.
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Luan, F, Liu, H, Gao, L, Liu, J, Sun, Z, Ju, Y, Hou, N, Guo, C, Liang, X, Zhang, L, Sun, W, Ma, C Tags: Hepatic cancer Hepatology Source Type: journals
A Crohn's disease patient with pustules and feverEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Bouma, G, Neve, S, van Grieken, N C T, Mulder, C J, Stoof, T J Tags: GUT Snapshot Editor's quiz Source Type: journals
The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 yearsEmail this article to a colleague.
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Conclusions:
Children with NAFLD may develop end-stage liver disease with the consequent need for liver transplantation. NAFLD in children seen in a tertiary care centre may be associated with a significantly shorter survival as compared to the general population.
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Feldstein, A E, Charatcharoenwitthaya, P, Treeprasertsuk, S, Benson, J T, Enders, F B, Angulo, P Tags: Nonalcoholic steatosis, Editor's choice Hepatology Source Type: journals
JournalScanEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Tags: JournalScan Source Type: journals
MicroRNAs: tools for cancer diagnosticsEmail this article to a colleague.
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Recently, a novel class of global gene regulators called microRNAs (miRNAs), were identified in both plants and animals. MiRNAs can reduce protein levels of their target genes with a minor impact on the target genes’ mRNAs. Accumulating evidence demonstrates the importance of miRNAs in cancer. MiRNAs that are overexpressed in cancer may function as oncogenes, and miRNAs with tumour suppressor activity in normal tissue may be downregulated in cancer. Although major advances have been achieved in our understanding of cancer biology, as well as in the development of new targeted therapies, the progress in developing imp...
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Paranjape, T, Slack, F J, Weidhaas, J B Tags: GUT Recent advances in basic science Source Type: journals
Diagnosis, management and prevention of drug-induced liver injuryEmail this article to a colleague.
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Drug-induced liver injury (DILI) is increasingly being recognised as a significant cause of both acute and chronic liver disease. The most commonly implicated agents are paracetamol, antimicrobials, non-steroidal anti-inflammatory drugs, statins, isoniazid and herbal remedies. Drug-induced hepatotoxicity is generally idiosyncratic in nature. The pathogenesis of DILI remains enigmatic, but involves exposure to the toxic agent, mitochondrial injury, failure of adaptation, and innate and adaptive immune responses. Diagnosis of drug-induced liver diseases can be difficult, but the key to causality is to diligently exclude othe...
Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Verma, S, Kaplowitz, N Tags: GUT Recent advances in clinical practice Source Type: journals
The contribution of megakaryocytes to liver fibrosisEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Thachil, J Tags: PostScript Source Type: journals
Letter in response to 'Coagulation and fibrosis in chronic liver disease'Email this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Borensztajn, K, Peppelenbosch, M P, Spek, C A Tags: PostScript Source Type: journals
Applicability of BARD score to Japanese patients with NAFLDEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Fujii, H, Enomoto, M, Fukushima, W, Tamori, A, Sakaguchi, H, Kawada, N Tags: PostScript Source Type: journals
Authors' replyEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Harrison, S A, Neuschwander-Tetri, B A Tags: PostScript Source Type: journals
Gastrointestinal manifestations among Chilean patients infected with novel influenza A (H1N1) 2009 virusEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Riquelme, A, Alvarez-Lobos, M, Pavez, C, Hasbun, P, Dabanch, J, Cofre, C, Jimenez, J, Calvo, M Tags: PostScript Source Type: journals
DigestEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Spiller, R., Vermeire, S. Tags: Digest Source Type: journals
Obesity and Barrett's oesophagus: more than just refluxEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Abrams, J. A Tags: Commentaries Source Type: journals
Corticosteroid treatment for autoimmune pancreatitisEmail this article to a colleague.
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Source: Gut - October 15, 2009 Category: Gastroenterology Authors: Pannala, R., Chari, S. T Tags: Commentaries Source Type: journals
