Gastroenterology
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog.
Subscribe to this data using MyMedWorm.
Subscribe to this data using GoogleReader.
Subscribe to this data using Bloglines.
Subscribe to this data using MyYahoo.
Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.
This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 22.
Reviewers
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Source: Colorectal Disease - October 11, 2009 Category: Gastroenterology Tags: Reviewers Source Type: journals
Ulcerative colitis in a Southern European country: A national perspective
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
The incidence, prevalence, and even the clinical behavior of ulcerative colitis (UC) are highly variable in different world regions. In previous studies, Portugal was reported as having a milder clinical behavior. The aim of this study was to apply the Montreal Classification in a large group of UC Portuguese patients in order to describe their clinical characteristics and evaluate variables potentially useful for outcome prediction.A cross-sectional study based on data collected from a nationwide online registry was undertaken.In all, 2863 patients with UC were included. Twenty-one percent had ulcerative proctitis, 52% le...
Source: Inflammatory Bowel Diseases - October 11, 2009 Category: Gastroenterology Authors: Francisco Portela, Fernando Magro, Paula Lago, José Cotter, Isabelle Cremers, João de Deus, Ana Vieira, Horácio Lopes, Paulo Caldeira, Luísa Barros, Jorge Reis, Laura Carvalho, Raquel Gonçalves, Mário J. Campos, Paula Ministro, Maria A. Duarte, Jorg Source Type: journals
Cerebral thromboembolic events in pediatric patients with inflammatory bowel disease
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
We describe the incidence and outcome of CTE in pediatric IBD patients from a single center over 5 years and the relative proportion of stroke reported in the literature in patients with UC and CD before and after January 2000.Demographic data were extracted on all newly diagnosed cases of IBD in our center from January 2003 to January 2008 to ascertain patient characteristics, disease type, risk factors for CTE, modality of neuroimaging, and outcome. A literature search was performed to identify all articles describing stroke in pediatric IBD. All identified studies were stratified into those published before and after Ja...
Source: Inflammatory Bowel Diseases - October 11, 2009 Category: Gastroenterology Authors: A.R. Barclay, J.M. Keightley, I. Horrocks, V. Garrick, P. McGrogan, R.K. Russell Source Type: journals
Mycobacterium avium subsp. Paratuberculosis (MAP) as a modifying factor in Crohn's disease
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Crohn's disease (CD) is a multifactorial syndrome with genetic and environmental contributions. Mycobacterium avium subspecies paratuberculosis (MAP) has been frequently isolated from mucosal tissues of patients with CD but the cellular immune response to this bacterium has been poorly described. Our aim was to examine the influence of MAP on T-cell proliferation and cytokine responses in patients with inflammatory bowel disease (IBD).Peripheral blood mononuclear cells (PBMCs) and mesenteric lymph node cells (MLNCs) were obtained from IBD patients and non-IBD controls. PBMC T-cell proliferation in response to MAP was deter...
Source: Inflammatory Bowel Diseases - October 11, 2009 Category: Gastroenterology Authors: Shomik Sibartie, Paul Scully, John Keohane, Shaun O'Neill, Jim O'Mahony, Deirdre O'Hanlon, William O. Kirwan, Liam O'Mahony, Fergus Shanahan Source Type: journals
The effect of hyperbaric oxygen on apoptosis and proliferation in severe acute pancreatitis
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: During SAP, acini apoptosis and proliferation were increased. Hyperbaric oxygen therapy may improve the condition of SAP by promoting apoptosis and proliferation.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 10, 2009 Category: Gastroenterology Authors: Shir Lin Koh, Joon Win Tan, Vijayaragavan Muralidharan, Christopher Christophi Source Type: journals
Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions Methylation levels in gastric mucosae decreased to certain levels after HP eradication in profiles unique to individual markers. Involvement of chronic inflammation in methylation induction was suggested.
Content Type Journal ArticleCategory Original Article—Alimentary TractDOI 10.1007/s00535-009-0142-7Authors
Takeshi Nakajima, National Cancer Center Research Institute Carcinogenesis Division 5-1-1 Tsukiji, Chuo-ku Tokyo 104-0045 JapanShotaro Enomoto, National Cancer Center Research Institute Carcinogenesis Division 5-1-1 Tsukiji, Chuo-ku Tokyo 104-0045 JapanSatoshi Yamashita, National Can...
Source: Journal of Gastroenterology - October 10, 2009 Category: Gastroenterology Tags: Journal of Gastroenterology Source Type: journals
A new approach to percutaneous transhepatic portal embolization using ethanolamine oleate iopamidol
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion EOI is a safe embolic material that can be used to induce greater liver hypertrophy, in comparison to fibrin glue, in PTPE
for liver tumors.
Content Type Journal ArticleCategory Original Article—Liver, Pancreas, and Biliary TractDOI 10.1007/s00535-009-0143-6Authors
Toru Beppu, Kumamoto University Department of Gastroenterological Surgery, Graduate School of Medical Sciences Honjo 1-1-1 Kumamoto 860-8556 JapanMasaaki Iwatsuki, Kumamoto University Department of Gastroenterological Surgery, Graduate School of Medical Sciences Honjo 1-1-1 Kumamoto 860-8556 JapanHirohisa Okabe, Kumamoto Univers...
Source: Journal of Gastroenterology - October 10, 2009 Category: Gastroenterology Tags: Journal of Gastroenterology Source Type: journals
Overlap of primary biliary cirrhosis and autoimmune hepatitis: Characteristics, therapy, and long term outcomes
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: PBC-AIH overlap is not a rare entity; it was observed in 11% of PBC patients in this study. Further studies will be required to investigate whether PBC-AIH overlap is distinct from the two individual diseases in terms of long-term outcomes and therapeutic implications.
Source: Journal of Gastroenterology and Hepatology - October 9, 2009 Category: Gastroenterology Authors: Junko Yokokawa, Hironobu Saito, Yukiko Kanno, Fumiko Honma, Kyoko Monoe, Natsumi Sakamoto, Kazumichi Abe, Atsushi Takahashi, Hirohide Yokokawa, Hiromasa Ohira Source Type: journals
Association between blood flow and inflammatory state in a T-cell transfer model of inflammatory bowel disease in mice
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Adoptive transfer of naive T-lymphocyte subsets into lymphopenic mice initiates chronic gut inflammation that mimics several aspects of inflammatory bowel disease (IBD). Patients with IBD can have profound alterations in intestinal blood flow, but whether the same is true in the T-cell transfer model has yet to be determined.In the current study, chronic intestinal inflammation was induced in recombinase-activating gene-1-deficient (RAG-/-) mice by adoptive transfer of CD4+ T-lymphocytes obtained from interleukin-10 deficient (IL-10-/-) mice.Four weeks later, widespread colonic inflammation was observed in the reconstitute...
Source: Inflammatory Bowel Diseases - October 9, 2009 Category: Gastroenterology Authors: Norman R. Harris, Patsy R. Carter, Seungjun Lee, Megan N. Watts, Songlin Zhang, Matthew B. Grisham Source Type: journals
The impact of pre-operative serum creatinine on short-term outcomes after liver resection
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: After liver resection, renal failure is rare but patients with an elevated creatinine pre-operatively are at an increased risk of both renal and non-renal complications.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 9, 2009 Category: Gastroenterology Authors: Thomas Armstrong, Fenella K.S. Welsh, John Wells, Kandiah Chandrakumaran, Timothy G. John, Myrddin Rees Source Type: journals
Cumulative sum (Cusum) analysis provides an objective measure of competency during training in endoscopic retrograde cholangio-pancreatography (ERCP)
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion: Cusum analysis enables sensitive and continuous monitoring of a trainee's performance to objectively determine competency. Wider and systematic use may enable appropriate benchmarks to be identified and more objective assessment of a trainee's experience.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 9, 2009 Category: Gastroenterology Authors: Hayley M. Waller, Saxon J. Connor Source Type: journals
Combined pancreaticoduodenectomy and extended right hemicolectomy: outcomes and indications
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: This series suggests that PD combined with an en bloc extended right hemicolectomy is feasible and can achieve complete tumour clearance with acceptable morbidity.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 9, 2009 Category: Gastroenterology Authors: Eric T. Kimchi, Mehrdad Nikfarjam, Niraj J. Gusani, Diego M. Avella, Kevin F. Staveley-O'Carroll Source Type: journals
Hepatic resection for large hepatocellular carcinoma in the era of UCSF criteria
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: Surgical resection, if feasible, is suggested in patients with large HCC and can be performed with acceptable overall and disease-free survival and morbidity rates. In patients eligible for transplantation, resection may also have a place in the management strategy when waiting list time is prolonged for reasons of organ shortage or when the candidate has low priority as a result of a low MELD (model for end-stage liver disease) score.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 9, 2009 Category: Gastroenterology Authors: Spiros G. Delis, Andreas Bakoyiannis, Nikos Tassopoulos, Kostas Athanassiou, Aristotelis Kechagias, Dimitrios Kelekis, Juan Madariaga, Christos Dervenis Source Type: journals
The role of PET-CT in patients with incidental gallbladder cancer
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: For patients presenting with stage T1b or greater IGC, the use of 18FDG PET-CT will help reduce the number of patients undergoing non-therapeutic re-exploration and may help to determine the likely prognosis. 18FDG PET-CT might be a useful tool for the selection of patients for potentially curative treatment.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 9, 2009 Category: Gastroenterology Authors: Jean M. Butte, Francisca Redondo, Enrique Waugh, Manuel Meneses, Rossana Pruzzo, Hugo Parada, Horacio Amaral, Hernán A. De La Fuente Source Type: journals
Photodynamic therapy is associated with an improvement in survival in patients with irresectable hilar cholangiocarcinoma
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion: This prospective clinical cohort study has demonstrated that radical surgery and palliative Photofrin-PDT are associated with an increased survival in patients with hilar cholangiocarcinoma.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - October 9, 2009 Category: Gastroenterology Authors: Aaron J. Quyn, Dorin Ziyaie, Francesco M. Polignano, Iain S. Tait Source Type: journals
Diet Supplements Do Not Affect Colorectal Cancer Markers
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Use of prebiotic, probiotic, and synbiotic dietary supplementation leads to changes in fecal microflora but not to variables associated with colorectal cancer, according to Australian and US researchers. Reuters Health Information
Source: Medscape Gastroenterology Headlines - October 9, 2009 Category: Gastroenterology Tags: Hematology-Oncology Source Type: info
H. pylori eradication prevention of gastric cancer questioned
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Eradicating Helicobacter pylori to treat peptic ulcers may not prevent gastric cancer, a large, prospective, Japanese study suggests.
Source: MedWire News - Gastroenterology - October 9, 2009 Category: Gastroenterology Source Type: news
Editorial Board
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Source: Digestive and Liver Disease - October 9, 2009 Category: Gastroenterology Source Type: journals
NASH and HCC
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Primary liver cancer is the fifth most common malignancy worldwide and the third leading cause of cancer mortality. Non-alcoholic fatty liver disease is the most common cause of chronic liver disease in the United States encompassing a spectrum of entities marked by hepatic steatosis in the absence of significant alcohol consumption. Although simple steatosis follows a generally benign course, the more aggressive form, non-alcoholic steatohepatitis, can progress to cirrhosis and result in complications including hepatocellular carcinoma. A significant number of cases of hepatocellular carcinoma remain cryptogenic without k...
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: John M. Page, Stephen A. Harrison Source Type: journals
Lifestyle Modification as the Primary Treatment of NASH
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This article reviews the rationale and data behind recommending lifestyle changes to prevent and reverse NASH, focusing specifically on changes that lead to increased physical activity in sedentary patients, changes in dietary habits, and decreased calorie consumption to achieve gradual and sustained weight loss in those who are overweight or obese. In a culture that values avoiding even minimal exertion these are not easy changes to make. Ultimately, the success of care providers in helping patients to recognize and overcome these barriers depends on a patient's motivation, but clinicians can be more persuasive and able t...
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Brent A. Neuschwander-Tetri Source Type: journals
Pharmacologic Therapy of Non-Alcoholic Steatohepatitis
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This article discusses this therapy, with particular emphasis on pharmacologic therapy.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Vlad Ratziu, Shira Zelber-Sagi Source Type: journals
Non-Alcoholic Fatty Liver Disease: Is Bariatric Surgery the Answer?
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
As the worldwide obesity epidemic continues to increase, the prevalence of non-alcoholic fatty liver disease (NAFLD) and specifically non-alcoholic steatohepatitis (NASH) will become increasingly prominent. NASH will surpass chronic hepatitis C infection as the primary indication for orthotopic liver transplantation in the near future. With the evolution of surgical techniques, bariatric surgery is currently recognized as the most effective method for achieving sustained weight loss and reversing numerous comorbidities in severely obese individuals. This review focuses on the potential risks and benefits of bariatric surge...
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Anjana A. Pillai, Mary E. Rinella Source Type: journals
Index
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Source Type: journals
Contents
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Source Type: journals
Forthcoming issues
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Source Type: journals
Preface
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Our understanding of nonalcoholic fatty liver disease (NAFLD) has grown exponentially in the past 29 years since Ludwig and colleagues first described the histologic lesions that comprise a subset of NAFLD known as nonalcoholic steatohepatitis (NASH). A recent PubMed search using the term “nonalcoholic fatty liver disease” generated 1475 articles published since 1980, of which 1405 were published since the year 2000. Concern for this liver disease is validated, as NAFLD is becoming, if it has not already become, the number one chronic liver disease in this country and in many others around the world. As the prevalence ...
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Stephen A. Harrison Source Type: journals
Epidemiology and Natural History of Non-Alcoholic Steatohepatitis
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This article describes the epidemiology and natural history of this disorder. It also describes current diagnostic and treatment methods and describes future implications NAFLD may have.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Curtis K. Argo, Stephen H. Caldwell Source Type: journals
Histopathology of Non-Alcoholic Fatty Liver Disease
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Current imaging methodologies can detect steatosis with increasing accuracy but cannot detect inflammation or pre-cirrhotic fibrosis or remodeling of the liver parenchyma. Imaging also cannot assess types or localization of hepatic steatosis. With the increased use of rodents to study NAFLD/NASH, careful analysis or reading highlights the fact that liver tissue evaluations reported in many of the popular animal models of NAFLD/NASH often do not imitate many of the significant aspects of the human disease, despite similar terminology applied by investigators. This review will focus on the findings in human disease.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Elizabeth M. Brunt Source Type: journals
Role of Insulin Resistance and Lipotoxicity in Non-Alcoholic Steatohepatitis
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
It is well established that the development of NAFLD and NASH are closely linked to an excess flow of free fatty acids (FFA) arising from dysfunctional/insulin resistant adipose tissue causing ectopic fat deposition in many organs. In the liver, when chronic lipid supply surpasses the metabolic ability to adapt it will induce hepatocellular damage as FFA are redirected into harmful pathways of non-oxidative metabolism with intracellular accumulation of toxic lipid-derived metabolites. Multiple mechanisms have been implicated including mitochondrial dysfunction, endoplasmic reticulum stress, and activation of multiple infla...
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Kenneth Cusi Source Type: journals
Apoptosis and Cytokines in Non-Alcoholic Steatohepatitis
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This article summarizes the process of apoptosis and roles of putative cytokines in progressive NAFLD.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Wing-Kin Syn, Steve S. Choi, Anna Mae Diehl Source Type: journals
Endoplasmic Reticulum Stress and the Unfolded Protein Response
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This article reviews the pathways by which the UPR unfolds and its potential role in the development and progression of NAFLD.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Ashwani Kapoor, Arun J. Sanyal Source Type: journals
Predictors of Steatohepatitis and Advanced Fibrosis in Non-Alcoholic Fatty Liver Disease
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Non-alcoholic fatty liver disease is the most common cause of chronic liver disease in the United States. The development of non-alcoholic steatohepatitis increases the risk for cirrhosis and its complications. The gold standard for diagnosis is liver biopsy, the costs and risks of which make it impractical. Some demographic factors, blood tests, and imaging studies can be used to predict a higher risk of steatohepatitis or advanced fibrosis, but are of limited sensitivity and specificity. More accurate predictors and scoring systems would allow identifying who would benefit most from liver biopsy and monitor disease progr...
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Mangesh Pagadala, Claudia O. Zein, Arthur J. McCullough Source Type: journals
New Imaging Techniques for Non-Alcoholic Steatohepatitis
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
No imaging modality has yet been proven to reliably differentiate simple hepatic steatosis from steatohepatitis. This review focuses on the predominant non-nuclear imaging modalities available to clinicians at the present time. The key feature of the techniques outlined in this review that demonstrate the most interesting results have one thing in common: imaging is not performed in a passive manner but is undertaken as a method to investigate functional differences between simple hepatic steatosis and steatohepatitis based upon the current working model for pathogenesis and progression. The purpose of this article is to r...
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Jeffrey D. Browning Source Type: journals
Fatty Liver and Liver Transplantation
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This article addresses some of these challenges.
Source: Clinics in Liver Disease - October 9, 2009 Category: Gastroenterology Authors: Edith Koehler, Kymberly Watt, Michael Charlton Source Type: journals
Cancer Signs in Teens Often Overlooked
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Title: Cancer Signs in Teens Often OverlookedCategory: Health NewsCreated: 10/9/2009 10:48:00 AMLast Editorial Review: 10/9/2009 10:48:10 AM
Source: MedicineNet Crohn's Disease General - October 9, 2009 Category: Gastroenterology Source Type: consumer
Ulcers: What Causes Ulcers?
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Title: Ulcers: What Causes Ulcers?Category: Doctor's ViewsCreated: 2/10/2005Last Editorial Review: 10/9/2009
Source: MedicineNet Crohn's Disease General - October 9, 2009 Category: Gastroenterology Source Type: consumer
Clinical significance of pT sub-classification in surgical pathology of colorectal cancer
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions pT3 sub-classification was significantly associated with patient outcome. In contrast, pT2 and pT4 sub-classification did
not show clinical significance.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00384-009-0801-4Authors
Marion J. Pollheimer, Medical University Institute of Pathology Auenbruggerplatz 25 8036 Graz AustriaPeter Kornprat, Medical University Department of Surgery, Division of General Surgery Auenbruggerplatz 29 8036 Graz AustriaVerena S. Pollheimer, Medical University Institute of Pathology Auenbruggerplatz 25 8036 Graz AustriaRichard A. Lindtner, Medical...
Source: International Journal of Colorectal Disease - October 9, 2009 Category: Gastroenterology Tags: International Journal of Colorectal Disease Source Type: journals
Capsule endoscopy for the small bowel in juvenile polyposis
syndrome: a case series
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
In conclusion, capsule endoscopy
provided information additional to conventional endoscopy in patients with
juvenile polyposis syndrome and was well tolerated. However, no lesions
requiring clinical intervention were identified and polyp numbers were small.
Capsule endoscopy may appropriately be used as a baseline investigation for the
identification of patients with large or dense small-bowel polyps for whom
ongoing small-bowel investigation would be recommended. Patients in whom polyps
are confined to the colon are unlikely to require ongoing small-bowel
review.[...]© Georg Thieme Verlag ...
Source: Endoscopy - October 9, 2009 Category: Gastroenterology Tags: Case report Source Type: journals
How can we really reduce the morbidity of inflammatory bowel disease — Research on genes and cytokines, or find out the causative factors in the environment?
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Dear Sir, Right now, millions of patients all over the world are suffering from the devastating inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC), both of which have very high incidences in children and adolescence and are still regarded as incurable. Currently, the main efforts of research on IBD remain largely on genes, cytokines, and other cellular and molecular changes, with the utmost finding by the recent genome-wide association study that more than 30 distinct susceptibility loci are associated with CD. It revealed the complex in the pathogenesis of IBD. However, all these ...
Source: Journal of Critical Care - October 9, 2009 Category: Gastroenterology Authors: Xiaofa Qin Tags: Letters to the editor Source Type: journals
Systematic review and meta-analysis on the adverse events of rimonabant treatment: Considerations for its potential use in hepatology
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions:
Rimonabant is associated with an increased risk of adverse events. Despite of an increasing interest for its use on fatty liver, the security profile and efficacy it is needs to be carefully assessed before its recommendation. At present the use of rimonabant on fatty liver cannot be recommended.
Source: BMC Gastroenterology - October 8, 2009 Category: Gastroenterology Authors: Norberto Chavez-TapiaFelix Tellez-AvilaGiorgio BedogniLory CroceFlora MasuttiClaudio Tiribelli Source Type: journals
Is there any association between disturbed gastrointestinal visceromotor and sensory function and impaired quality of life in functional dyspepsia?
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions & Inferences In EPS and PDS, delayed gastric empting and altered sensory function are disease markers but not directly linked to the severity of HRQOL impairment or clinical presentation of FD.
Source: Neurogastroenterology and Motility - October 8, 2009 Category: Gastroenterology Authors: s. haag, w. senf, s. tagay, g. heuft, g. gerken, n. j. talley, g. holtmann Source Type: journals
Monitoring of CD95 and CD38 expression in peripheral blood T lymphocytes during active human cytomegalovirus infection after orthotopic liver transplantation
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: The present study showed that CD38+CD8+ T cells can be an appropriate immunological marker for early detection and antiviral therapeutic monitoring of HCMV infection. The evaluation of CD95 molecule levels may be used routinely in clinical practice to assess the level of immunosuppression.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Yuliang Wang, Yawu Liu, Ruifa Han, Qiang Li, Zhi Yao, Wenyan Niu, Yuhua Yuan, Zhiqin Tang, Zhijun Zhu, Zhongyang Shen Source Type: journals
Renal failure in patients with hepatocellular carcinoma and ascites undergoing transarterial chemoembolization
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
This study aimed to investigate the incidence and risk factors of ARF and prognostic predictors in HCC patients with ascites undergoing TACE. A total of 591 HCC patients receiving TACE were enrolled. In a mean follow-up duration of 19±17 months, 239 (40.4%) patients undergoing TACE died. Ascites, which was present in 91 (15.4%) patients at entry, independently predicted a poor prognosis in the Cox proportional hazard model [risk ratio (RR): 1.71, P=0.002]. Of these, 11 (12.6%) of 87 patients with complete follow-up developed ARF after TACE. Serum albumin level 400 ng/ml (RR: 1.84, P=0.04), multiple tumours (RR: 2.11, P=0....
Source: Liver International - October 8, 2009 Category: Gastroenterology Authors: Chia-Yang Hsu, Yi-Hsiang Huang, Chien-Wei Su, Han-Chieh Lin, Jen-Huey Chiang, Pui-Ching Lee, Fa-Yauh Lee, Teh-Ia Huo, Shou-Dong Lee Source Type: journals
Cow's milk protein allergy: An entity for recognition in developing countries
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: CMPA is not uncommon in a developing country such as India. Presence of aphthous ulcers and abnormal rectal biopsy are clues to initial diagnosis. Milk challenge confirms the diagnosis in all if it is done on time.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Ujjal Poddar, Surender Kumar Yachha, Narendra Krishnani, Anshu Srivastava Source Type: journals
Diagnosis of obscure gastrointestinal hemorrhage with capsule endoscopy in combination with multiple-detector computed tomography
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion: The contribution of CE is critical in the diagnosis of GHOO, given the fact that there is a significant difference in the detection rate between CE and MDCT, but there is no significant difference in the rate between CE plus MDCT and CE alone.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Bing-Ling Zhang, Ling-Ling Jiang, Chun-Xiao Chen, Bai-Shu Zhong, You-Ming Li Source Type: journals
Simple diagnostic approach to childhood fecal retention using the Leech score and Bristol stool form scale in medical practice
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: The Leech score and the Bristol stool form scale may be simple and useful diagnostic tools for pediatricians to access childhood fecal loading in outpatient clinics along with a thorough clinical history.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Hong Koh, Mi Jung Lee, Myung Joon Kim, Jae Il Shin, Ki Sup Chung Source Type: journals
Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion: Since the presence of the rs2304052 C allele is associated with an increased risk (odds ratio: 2.76) of developing hepatocarcinoma, our results allowed us to identify a SNP in the SPARC gene correlating to HCC susceptibility.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Ludovica Segat, Michele Milanese, Doroti Pirulli, Chiara Trevisiol, Francesco Lupo, Mauro Salizzoni, Antonio Amoroso, Sergio Crovella Source Type: journals
Ursodeoxycholic acid and artesunate in the treatment of severe falciparum malaria patients with jaundice
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: In severe PF malaria patients with jaundice, combined therapy with UDCA and artesunate is safe, but does not significantly improve liver tests compared to placebo and artesunate.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Sombat Treeprasertsuk, Udomsak Silachamroon, Srivicha Krudsood, Arun Huntrup, Plengsakoon Suwannakudt, Suparp Vannaphan, Polrat Wilairatana Source Type: journals
Therapeutic effects of pegylated interferon plus ribavirin in chronic hepatitis C patients with occult hepatitis B virus dual infection
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusion: Occult HBV infection in CHC patients is rare. The biochemical and virological responses to combined PEG[ndash]IFN and RBV therapy might be similar in CHC patients with or without occult HBV infection. The serum HBV[ndash]DNA level was low in patients with occult HBV/HCV dual infection who responded to combined therapy.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Li-Wei Chen, Rong-Nan Chien, Cho-Li Yen, Jia-Jang Chang, Ching-Jung Liu, Chih-Lang Lin Source Type: journals
High incidence of zinc deficiency among Filipino children with compensated and decompensated liver disease
Email this article to a colleague.
Save this article to My Clippings.
Discuss or comment on this article.
Conclusions: Children with chronic liver disease, whether in a compensated or decompensated state, had lower serum zinc levels compared with the healthy controls. As the severity of liver disease worsened, the zinc levels decreased. The study suggests that zinc supplementation should constitute part of the micronutrient intake of children with chronic liver disease.
Source: Journal of Gastroenterology and Hepatology - October 8, 2009 Category: Gastroenterology Authors: Perlina Umusig-Quitain, Germana V Gregorio Source Type: journals
