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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 27.

Molecular ‘portraits’ of tumours match patients with trials in everyday clinical practice
Researchers in France are taking advantage of the progress in genetic and molecular profiling to analyse the make-up of individual cancer patients’ tumours and, using this information, assign them to particular treatments and phase I clinical trials – an approach that could become part of everyday clinical practice.
Source: ScienceDaily Headlines - November 8, 2012 Category: Science Source Type: news

Researchers Introduce New Genetics-Based Lung Cancer Test to Predict Chemotherapy Response
Response Genetics adapted two of their existing tests to identify a larger population of non-small cell lung cancer patients who could benefit from the chemotherapy drug crizotinib.
Source: Asbestos and Mesothelioma News - November 8, 2012 Category: Environmental Health Authors: faith Tags: Treatment Lung Cancer Research Source Type: news

Unexplained intellectual disability explained by state-of-the-art genetic analysis
A research team reported that next generation sequencing of the exome, the one to two percent of the DNA containing the genes that code for proteins, enabled the identification of the genetic causes of unexplained intellectual disability in over 50 percent of patients in a study.
Source: ScienceDaily Headlines - November 8, 2012 Category: Science Source Type: news

Genetically modified foods measure fails
At every election, California's ballot is filled with initiatives, but none received more attention this year than Proposition 37.
Source: CNN.com - Health - November 8, 2012 Category: Consumer Health News Source Type: news

Genetic Risk for Alzheimer's Manifests Early (CME/CE)
(MedPage Today) -- Patients at genetic risk for Alzheimer's disease developed changes in the brain in their 20s, long before clinical symptoms would have been expected to appear, two imaging studies showed.
Source: MedPage Today Neurology - November 8, 2012 Category: Neurology Source Type: news

MicroRNAs in plants: Regulation of the regulator
MicroRNAs are essential regulators of the genetic program in multicellular organisms. Because of their potent effects, the production of these small regulators has itself to be tightly controlled, new research demonstrates.
Source: ScienceDaily Headlines - November 8, 2012 Category: Science Source Type: news

Scientists uncover secrets of how intellect and behavior emerge during childhood
This study helps explain how genetic mutations can cause profound cognitive and behavioral problems.
Source: ScienceDaily Headlines - November 8, 2012 Category: Science Source Type: news

New, improved mouse model of human Alzheimer's may enable drug discovery
Researchers have developed a transgenic mouse that carries a human gene known to increase risk of Alzheimer's 15-fold. The new mouse, which mimics the genetics of the human disease more closely than any existing model, provides new evidence for the earliest cause of Alzheimer's and may prove more useful in the development of drugs to prevent or treat the disease.
Source: ScienceDaily Headlines - November 8, 2012 Category: Science Source Type: news

The Origins of Shame
Joseph Burgo, Ph.D. discusses a video lecture by Allan Schore of the UCLA Department of Psychiatry and Behavioral in which he and other researchers show how failures of attachment during the first two years of life permanently affect and limit brain development in the infant.read more
Source: Psychology Today Parenting Center - November 8, 2012 Category: Psychiatry & Psychology Authors: Joseph Burgo, Ph.D. Tags: Child Development Neuroscience Parenting Therapy allan schore attachment theory behavioral sciences brain stem caretakers clinical faculty fallacies genetic makeup genetic material heredity lecturer myelinated narcissism Source Type: news

Preclinical muscular dystrophy data shows promise
Researchers have found that an experimental compound may help stem the debilitating effects of muscular dystrophy by restoring normal blood flow to muscles affected by the genetic disorder.
Source: ScienceDaily Headlines - November 8, 2012 Category: Science Source Type: news

Genetically modified foods prop fails
At every election, California's ballot is filled with initiatives, but none received more attention this year than Proposition 37.
Source: CNN.com - Health - November 8, 2012 Category: Consumer Health News Source Type: news

'Autism gene discovered' by researchers
Conclusion This study provides a target for future research into autistic spectrum disorders. The researchers have characterised the role that one protein plays in the signalling process of certain brain cells. But whether this research ultimately leads to the development of treatments for ASDs remains to be seen. Even if further research reveals that the mutations to the ProSAP2/Shank3 protein play a causative role in autism, it is unlikely to account for or lead to a treatment for all ASDs. The various types of ASD suggest a complex origin of the disorders and a mutation to a single gene is unlikely to account for all t...
Source: NHS News Feed - November 8, 2012 Category: Consumer Health News Tags: Genetics/stem cells Neurology Mental health Source Type: news

New American Chemical Society Prized Science Video: Personalizing Medicine
Personalized medicine - the promise of customizing treatments that will work best for each individual patient - could get a boost from advances in understanding how the proteins that help determine health and disease take the three-dimensional shapes needed to work in the body. That's the message of the latest episode of the 2012 edition of a popular video series from the American Chemical Society (ACS), the world's largest scientific society. The videos are available at www.acs.org/PrizedScience and on DVD...
Source: Health News from Medical News Today - November 8, 2012 Category: Consumer Health News Tags: Genetics Source Type: news

Scottsdale student creates tennis match to benefit TGen cancer research
Nov. 11 ‘Rally for Research’ pairs kids and adults in doubles tournament
Source: TGen News - November 8, 2012 Category: Genetics & Stem Cells Authors: TGEN Tags: Science News Source Type: news

New Method Helps Link Genomic Variation To Protein Production
Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according to a presentation at the American Society of Human Genetics 2012 meeting in San Francisco. In the 0.1% of the DNA that differs between any two individuals, scientists search for the biological mechanisms underlying human genetic differences, including disease susceptibility...
Source: Health News from Medical News Today - November 8, 2012 Category: Consumer Health News Tags: Genetics Source Type: news

DNA Sequencing Of Infants And Children With Anatomical Defects Of Unknown Causes
A presentation at the American Society of Human Genetics 2012 meeting updated genetics experts about a one-year-old research initiative that brought together researchers, clinicians and policy experts to tackle the challenges of incorporating new genomic technologies into clinical care of newborns, infants and children with anatomical defects whose causes are unknown. Among the challenges is interpreting how variations in patients' DNA cause or contribute to their medical problems, said Duke University Assistant Professor of Pediatrics Erica E. Davis, Ph.D...
Source: Health News from Medical News Today - November 8, 2012 Category: Consumer Health News Tags: Genetics Source Type: news

Genetic mutation discovered in people with autism
A genetic mutation that cuts communication between brain cells to about one-tenth of normal levels has been discovered in people with autism.
Source: Telegraph Health - November 8, 2012 Category: Consumer Health News Source Type: news

Next up on the list of ridiculous jabs: A 'bad fat-battling' vaccine
There are a variety of reasons why Americans in particular tend to struggle with weight issues -- a heavily-processed, high-grain diet tainted with all sorts of genetically-modified organisms (GMOs) and synthetic additives is just one reason among many why as many as...
Source: NaturalNews.com - November 8, 2012 Category: Consumer Health Advice Source Type: news

Oregon court temporarily halts GM canola plantings after determining crop will cause 'irreparable harm' to important growing region
Efforts by the biotechnology industry to begin planting genetically-modified (GM) canola, also known as rapeseed, in Oregon's prized Willamette Valley have been thwarted, at least temporarily, thanks to persistent opposition from farmers and farmer advocacy groups. The...
Source: NaturalNews.com - November 8, 2012 Category: Consumer Health Advice Source Type: news

Total hypocrisy: Monsanto, agribusiness and big food companies spent more than $45 million to kill 'costly' Prop 37 GMO labeling bill
Labeling genetically-modified organisms (GMOs) is simply too costly, and any law requiring that GMOs be properly labeled will raise food prices significantly. This was one of the many lies propagated by the biotechnology and processed food industries in the months and...
Source: NaturalNews.com - November 8, 2012 Category: Consumer Health Advice Source Type: news

After Loss, Fight to Label Modified Food Continues
Advocates of the labeling of genetically modified food vowed to carry their fight to other states and to the federal government after suffering a defeat in California.
Source: NYT Health - November 8, 2012 Category: Consumer Health News Authors: By ANDREW POLLACK Tags: Biotechnology Mondelez International Inc. MDLZ NASDAQ Pepsico Inc PEP NYSE Monsanto Company MON NYSE Labeling and Labels Food DuPont Co DD NYSE Coca-Cola Company KO NYSE Elections California Source Type: news

Molecular 'portraits' of tumors match patients with trials in everyday clinical practice
(ECCO-the European CanCer Organisation) Researchers in France are taking advantage of the progress in genetic and molecular profiling to analyse the make-up of individual cancer patients' tumours and, using this information, assign them to particular treatments and phase I clinical trials -- an approach that could become part of everyday clinical practice. The research is presented at the 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.
Source: EurekAlert! - Cancer - November 8, 2012 Category: Cancer & Oncology Source Type: news

Renewal grant supports genetic research into arthritis of the spine
(University of Texas Health Science Center at Houston) An international team of scientists searching for genes that determine the susceptibility and severity of arthritis of the spine has been awarded a five-year renewal grant of $4.3 million from the National Institutes of Health.
Source: EurekAlert! - Medicine and Health - November 8, 2012 Category: Global & Universal Source Type: news

Molecular 'portraits' of tumours match patients with trials in everyday clinical practice
(ECCO-the European CanCer Organisation) Researchers in France are taking advantage of the progress in genetic and molecular profiling to analyse the make-up of individual cancer patients' tumours and, using this information, assign them to particular treatments and phase I clinical trials -- an approach that could become part of everyday clinical practice. The research is presented at the 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.
Source: EurekAlert! - Cancer - November 8, 2012 Category: Cancer & Oncology Source Type: news

MicroRNAs in plants: Regulation of the regulator
(Max-Planck-Gesellschaft) MicroRNAs are essential regulators of the genetic program in multicellular organisms. Because of their potent effects, the production of these small regulators has itself to be tightly controlled. That is the key finding of a new study performed by Tuebingen scientists at the Max Planck Institute for Developmental Biology.
Source: EurekAlert! - Biology - November 8, 2012 Category: Biology Source Type: news

Regular exercise of benefit even without weight loss
Life expectancy greater at even moderate physical activity levelsRelated items from OnMedicaMedicine must embrace sport and exercise, say PhysiciansLack of exercise global killer on a par with smoking and obesityExercise programme cuts falls in the elderlyCombine aerobics and weights for diabetesExercise tackles ‘genetic’ obesity
Source: OnMedica Latest News - November 8, 2012 Category: UK Health Source Type: news

Autism Speaks announces the release of new genetic data for researchers
(Autism Speaks) Autism Speaks has released biological and clinical data from 383 new families (653 individuals) participating in Autism Speaks Autism Genetic Resource Exchange (AGRE) to researchers. This resource for scientists is comprised of clinical and biological data from families who have two or more children on the autism spectrum. This brings the total data available on people with an ASD to 3348 and affected family members without an ASD to 9335 individuals, more than a 24 percent increase.
Source: EurekAlert! - Social and Behavioral Science - November 8, 2012 Category: Global & Universal Source Type: news

Teleconcussion--A new, innovative strategy for assessing young athletes
(Mary Ann Liebert, Inc./Genetic Engineering News) Concussion is a common disorder estimated to affect no fewer than 1.7-3.8 million people in the US each year. Many more people with concussion likely do not seek medical care for symptoms of concussion and may suffer long-lasting, progressive, and profoundcognitive, psychiatric, and neurologic effects.
Source: EurekAlert! - Medicine and Health - November 8, 2012 Category: Global & Universal Source Type: news

New, improved mouse model of human Alzheimer's may enable drug discovery
(University of Illinois at Chicago) Researchers have developed a transgenic mouse that carries a human gene known to increase risk of Alzheimer's 15-fold. The new mouse, which mimics the genetics of the human disease more closely than any existing model, provides new evidence for the earliest cause of Alzheimer's and may prove more useful in the development of drugs to prevent or treat the disease.
Source: EurekAlert! - Medicine and Health - November 8, 2012 Category: Global & Universal Source Type: news

California rejects labeling of genetically altered food
LOS ANGELES/KANSAS CITY (Reuters) - California voters rejected a ballot measure that would have made the state the first in the nation to require special labeling of foods with genetically modified ingredients.
Source: Modern Medicine - November 8, 2012 Category: Journals (General) Source Type: news

Firm molecular handshake needed for hearing and balance
Researchers have mapped the precise 3-D atomic structure of a thin protein filament critical for cells in the inner ear and calculated the force necessary to pull it apart. These findings show the characteristics of the most vulnerable area of a structure called the tip link, and open avenues for research in fields related to noise-induced hearing loss and certain genetic diseases.
Source: ScienceDaily Headlines - November 7, 2012 Category: Science Source Type: news

American Society of Human Genetics (ASHG) 62nd Annual MeetingAmerican Society of Human Genetics (ASHG) 62nd Annual Meeting
Read clinically focused news coverage of key developments from ASHG 2012. Medscape Pathology
Source: Medscape Today Headlines - November 7, 2012 Category: Consumer Health News Tags: Conference Coverage Source Type: news

Parents of baby who died from a genetic fault that went undetected sue hospital for £300,000
Jasper Allibone's parents are suing a London hospital for £300,000 for failing to spot a rare genetic fault they claim killed him aged three months.
Source: the Mail online | Health - November 7, 2012 Category: Consumer Health News Source Type: news

Boston Children’s brings CLARITY to families living with complex diseases
Genome sequencing may help parents of children with rare disease The future of medicine is closer than you think. Today, scientists are able to learn more than ever about how our genes are likely to affect our health—and the diseases or conditions we may face later in life—thanks to a process known as genome sequencing (in-depth studying of our DNA). And because of technological advances made in recent years, the process has become less expensive, meaning it could soon be an important aspect of everyday care. (A decade ago it cost $3 million to sequence a person’s genes. Today the process runs about $1,000.) But...
Source: Thrive, Children's Hospital Boston - November 7, 2012 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Children's in the news Diseases & conditions Our patients’ stories Research Gene Partnership Project (GPP) gene therapy genes genetic conditions genetics Source Type: news

Fossils and genes brought together to piece together evolutionary history
Scientists have reviewed recent studies that have used modern genetic techniques to shed light on fossils, and vice versa.
Source: ScienceDaily Headlines - November 7, 2012 Category: Science Source Type: news

California Rejects Labeling Of Genetically Modified Food; Supporters Vow To Fight On
A closely watched vote on food labeling ends at California's ballot box, but supporters of genetically modified food labeling say a new food movement is just getting warmed up. Labeling supporters were far outspent by opponents like major food companies Monsanto and Kraft.» E-Mail This » Add to Del.icio.us
Source: NPR Health and Science - November 7, 2012 Category: Consumer Health News Source Type: news

Prop 37: Californian voters reject GM food labelling
Polls show 53.7% voted against the contentious measure that was seen as a testbed case for the US as a wholeA Californian ballot proposing the labelling of genetically modified ingredients in food products has been rejected by the state's voters .With 95% of votes counted, the polls showed 47% voted in favour and 53% against. The contentious measure, proposition 37, would have required GM labels on food sold in supermarkets, and was seen as a testbed case for the US as a whole.Monsanto and other agribusiness and food companies such as PepsiCo and Nestle spent $45m on advertising and lobbying for the "no" campaign, compared...
Source: Guardian Unlimited Science - November 7, 2012 Category: Science Authors: Adam Vaughan Tags: United States Farming World news guardian.co.uk Food GM Environment Science Source Type: news

Addiction History In Smokers' DNA May Show Cancer Risk
Smokers leave a chemical "footprint" of their addiction history on the surface of their DNA, and this may serve as a measure of their risk for developing cancer, say researchers from the UK and Italy who presented their findings at a conference in Liverpool, UK, this week. While the underlying genetic code of DNA remains unaltered, a history of smoking leaves a footprint on the surface of DNA, something that is referred to as an "epigenetic modification". Epigenetic modifications don't change the underlying genomic code as such, but they influence how it is interpreted...
Source: Health News from Medical News Today - November 7, 2012 Category: Consumer Health News Tags: Genetics Source Type: news

Whole-Genome Sequencing Trials Suggest Time Has Come to Bring Personalized Medicine to Cancer Field
Pathologists will be interested to learn how French researchers used whole genome sequencing of breast cancer tumors to help with diagnosis and decisions about therapy Pathologists take note! Human whole-genome sequencing of tumors was the source of information for making treatment decisions in a recently-published study. For the first time, researchers conducted a large trial [...]
Source: Dark Daily - November 7, 2012 Category: Laboratory Medicine Authors: jude Tags: Digital Pathology Instruments & Equipment Laboratory News Laboratory Operations Laboratory Pathology biomarker clinical laboratory ESMO European Society for Medical Oncology Fabrice André genetic testing INSERM Institut Gustave Ro Source Type: news

Prop 37: Californian voters likely to reject GM food labelling
With four in five votes counted, the polls showed 46.3% voting in favour and 53.7% against the contentious measureA Californian ballot proposing the labelling of genetically modified ingredients in food products looks likely to be rejected by the state's voters on Wednesday.With four in five votes counted, the polls showed 46.3% voting in favour and 53.7% against. The contentious measure, proposition 37, would have required GM labels on food sold in supermarkets, and was seen as a testbed case for the US as a whole.Monsanto and other agribusiness and food companies such as PepsiCo and Nestle spent $45m on advertising and l...
Source: Guardian Unlimited Science - November 7, 2012 Category: Science Authors: Adam Vaughan Tags: United States Farming World news guardian.co.uk Food GM Environment Science Source Type: news

How mum's menopause can affect your fertility
Conclusion This cross-sectional study highlighted a relationship between early maternal age of menopause (before 45 years of age) and lower levels of ovarian reserve in their daughters. The strengths of this study include its moderately large sample size and its dual methods of estimating ovarian reserve. However, the study also has significant limitations. Information on age at maternal menopause was obtained retrospectively, and may be prone to recall bias and a tendency to round to simple, easy-to-remember numbers. For example, a woman may have experienced her menopause at the age of 47, but her daughter may remember it...
Source: NHS News Feed - November 7, 2012 Category: Consumer Health News Tags: Pregnancy/child Source Type: news

NHLBI Exome Sequencing Project Reported Surprising Findings
A multi-institutional team of researchers has sequenced the DNA of 6,700 exomes, the portion of the genome that contains protein-coding genes, as part of the National Heart, Lung and Blood Institute (NHLBI)-funded Exome Sequencing Project, one of the largest medical sequencing studies ever undertaken. Scientists participating in the project initially expected that individual rare variants would have a greater effect on over 80 heart, lung and blood related traits and diseases of high public health significance, said Suzanne M. Leal, Ph.D...
Source: Health News from Medical News Today - November 7, 2012 Category: Consumer Health News Tags: Genetics Source Type: news

In Children With 22q11.2 Deletion Syndrome, Higher Anxiety Associated With Poorer Functioning
UC Davis researchers have found that for children with the genetic disorder known as chromosome 22q11.2 deletion syndrome anxiety - but not intelligence - is linked to poorer adaptive behaviors, such as self-care and communication skills, that affect daily life. The developmental syndrome, which is associated with a constellation of physical, cognitive and psychiatric problems, usually is apparent at birth or early childhood, and leads to lifelong challenges...
Source: Health News from Medical News Today - November 7, 2012 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news

Growth Of Cystic Kidney Halted
Autosomal-dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders, affecting one in every 1,000 people and responsible for up to ten percent of patients on dialysis worldwide. The disease is characterized by the development of cysts that lead to progressive kidney failure and necessitate dialysis or a kidney transplant in most patients aged around fifty. Moreover, the persistent cyst growth causes high blood pressure and painful complications...
Source: Health News from Medical News Today - November 7, 2012 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Plaque Build-Up In Mice Decreased By Consumption Of Genetically Engineered Tomatoes
For the first time, genetically engineered tomato plants produced a peptide that mimics the actions of good cholesterol when eaten, researchers reported at the American Heart Association's Scientific Sessions 2012. In the study, mice that ate the freeze-dried, ground tomatoes had less inflammation and reduced atherosclerosis (plaque build-up in the arteries). "We have found a new and practical way to make a peptide that acts like the main protein in good cholesterol, but is many times more effective and can be delivered by eating the plant," said Alan M. Fogelman, M.D...
Source: Health News from Medical News Today - November 7, 2012 Category: Consumer Health News Tags: Cholesterol Source Type: news

Lower Vitamin D Levels, Genetic Variants And Familial Longevity
Low levels of vitamin D may be associated with longevity, according to a study involving middle-aged children of people in their 90s published in CMAJ (Canadian Medical Association Journal). "We found that familial longevity was associated with lower levels of vitamin D and a lower frequency of allelic variation in the CYP2R1 gene, which was associated with higher levels of vitamin D," writes Dr. Diana van Heemst, Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands, with coauthors...
Source: Health News from Medical News Today - November 7, 2012 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

GMOs - Suspected culprit in devastating 'fiber disease'
Straight out of a sci-fi horror film, a mysterious disease that produces sores, rashes and sharp fibers beneath the skin may be linked with genetically modified organisms. Along with bug-like crawling sensations, Morgellons disease causes other alarming symptoms: extreme...
Source: NaturalNews.com - November 7, 2012 Category: Consumer Health Advice Source Type: news

Children activists join the battle for GMO food labeling, fighting for 'real food'
An unanticipated but welcomed voice in the debate over whether or not to label genetically-modified organisms (GMOs), children are increasingly speaking the bold truth to their peers and even adults about the importance of eating real food, according to a recent CNN...
Source: NaturalNews.com - November 7, 2012 Category: Consumer Health Advice Source Type: news

Cedars-Sinai research: Preclinical muscular dystrophy data shows promise
(Cedars-Sinai Medical Center) Cedars-Sinai Heart Institute researchers have found that an experimental compound may help stem the debilitating effects of muscular dystrophy by restoring normal blood flow to muscles affected by the genetic disorder.
Source: EurekAlert! - Medicine and Health - November 7, 2012 Category: Global & Universal Source Type: news

Recent studies bring fossils and genes together to piece together evolutionary history
(Society of Vertebrate Paleontology) In the current issue of the Journal of Vertebrate Paleontology, Hans Thewissen, Ingalls-Brown Professor at Northeast Ohio Medical University (NEOMED), and his colleagues review recent studies that have used modern genetic techniques to shed light on fossils, and vice versa.
Source: EurekAlert! - Biology - November 7, 2012 Category: Biology Source Type: news