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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

Iron deficiency, Helicobacter infection and gastritis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite elegant regulatory mechanisms, iron deficiency anemia (IDA) remains one of the most common nutritional deficiencies of mankind. Iron deficiency is the result of an interplay between increased host requirements, limited external supply, and increased blood loss. When related to increased physiologic needs associated with normal development, iron deficiency is designated physiologic or nutritional. By contrast, pathological iron deficiency, with the exception of gross menorrhagia, is most often the result of gastrointestinal disease associated with abnormal blood loss or malabsorption. If gastroenterologic evalua...
Source: Acta Haematologica - November 13, 2009 Category: Hematology Authors: Hershko C, Ronson A Tags: Acta Haematol Source Type: journals

CLL: promiscuity leads to risksEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Blood)
Source: Blood - October 22, 2009 Category: Hematology Authors: Stamatopoulos, K. Tags: INSIDE BLOOD Source Type: journals

A comprehensive evaluation of the prognostic significance of 13q deletions in patients with B-chronic lymphocytic leukaemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Deletion 13q14 on fluorescence in situ hybridization (FISH) analysis is the most common cytogenetic abnormality in chronic lymphocytic leukaemia (CLL), and is a favourable prognostic biomarker when detected as a sole abnormality. We intensively interrogated clinical outcome in 323 consecutive, untreated CLL patients with isolated 13q- identified within 2 years of diagnosis. We also analyzed outcome in 217 additional patients with deletion 11q22.3 or 17p13.1, or trisomy 12, based on whether these occurred in isolation or in conjunction with 13q-. Patients with a heterozygous 13q- and those with a homozygous deletion had sim...
Source: British Journal of Haematology - November 8, 2009 Category: Hematology Authors: Daniel L. Van Dyke, Tait D. Shanafelt, Timothy G. Call, Clive S. Zent, Stephanie A. Smoley, Kari G. Rabe, Susan M. Schwager, Jessica C. Sonbert, Susan L. Slager, Neil E. Kay Source Type: journals

State of the art in the treatment of CLLEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in adults in the Western world and predominantly affects the elderly. Although CLL remains incurable with standard treatments, important progress in treatment, which classically is given only when the disease has become symptomatic, has been made in recent years. The diagnosis of CLL does not necessarily convey the necessity of treatment. However, treatment has classically been indicated in symptomatic or progressive disease according to criteria defined by stage of disease. Treatment of CLL has been markedly improved by highly effective new drugs and d...
Source: Revista Brasileira de Hematologia e Hemoterapia - October 2, 2009 Category: Hematology Source Type: journals

Medical Articles 6/2Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fluoropolymer Based on a Polyaspartamide containing 1,2,4-Oxadiazole Units: A Potential Artificial Oxygen (O(2)) Carrier. Information is temporarily unavailable. Invasive pulmonary aspergillosis with hematological malignancy caused by Aspergillus terreus and in vitro susceptibility of A. terreus isolate to micafungin. Information is temporarily unavailable. A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia. Information is temporarily unavailable. Farnesyl transferase inhibitor resistance probed by target mutagenesis. (Source: CML Newswire)
Source: CML Newswire - June 3, 2007 Category: Hematology Authors: Rob Tags: Uncategorized Source Type: news

Medical Articles 5/2Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Long-term follow-up of children who underwent hematopoeitic cell transplant (HCT) for AML or ALL at less than 3 years of age. Information is temporarily unavailable. Parapharyngeal abscess by Aspergillus flavus in a neutropenic patient with myelogenous leukaemia. Information is temporarily unavailable. Chronic myelogenous leukemia progenitors display a genetically unstable personality. Information is temporarily unavailable. Fludarabine and busulfan as a myeloablative conditioning regimen for allogeneic stem cell transplantation in high- and standard-risk leukemic patients. (Source: CML Newswire)
Source: CML Newswire - May 3, 2007 Category: Hematology Authors: Rob Tags: Uncategorized Source Type: news

Listing Of CML Clinical TrialsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell TransplantConditions: Cancer; Fatigue; Pain; Psychosocial Effects and Treatment142.RecruitingMoxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With CancerConditions: Adult Solid Tumor; Fever, Sweats, and Hot Flashes; Hematopoietic and Lymphoid Cancer; Infection; Neutropenia143.RecruitingTacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplantation for Hematologic CancerConditions: Childhood Hodgkin's Lymphoma; Childhood ...
Source: CML Newswire Archives: CMLHope.Com - June 3, 2006 Category: Hematology Authors: Rob Source Type: news

Aggressive Prostate Cancer Linked to Trichomonas (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The sexually transmitted infection Trichomonas vaginalis increases risk of clinically-relevant, aggressive prostate cancer, researchers affirmed. (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - September 9, 2009 Category: Hematology Source Type: news

Medical Articles 9/14Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Successfully treated Candida krusei infection of the lumbar spine with combined caspofungin/posaconazole therapy. Information is temporarily unavailable. MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment. Information is temporarily unavailable. Phase 1 study of tipifarnib in combination with imatinib for patients with chronic myelogenous leukemia in chronic phase after imatinib failure. Information is temporarily unavailable. Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia. Information is ...
Source: CML Newswire - September 15, 2007 Category: Hematology Authors: Rob Tags: Uncategorized Source Type: news

Some H. pylori Strains Reduce Esophageal Adenocarcinoma RiskEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
BETHESDA, Md. (MedPage Today) -- Strains of Helicobacter pylori associated with an increased risk of gastric cancer may have a protective effect for esophageal adenocarcinoma, a meta-analysis found. (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - October 6, 2008 Category: Hematology Source Type: news

Venous thromboembolism in recurrent ovarian cancer-patients: A systematic evaluation of the North-Eastern German Society of Gynaecologic Oncology Ovarian Cancer Study Group (NOGGO)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: ROC-patients appear to have the highest risk for developing VTE when ascites exists and during the first 2 months following chemotherapy initiation. In contrast to primary ovarian cancer, VTE could not be identified to affect overall survival in relapsed malignant ovarian disease. (Source: Thrombosis Research)
Source: Thrombosis Research - October 20, 2009 Category: Hematology Authors: C. Fotopoulou, A. Karavas, R. Trappe, R. Chekerov, W. Lichtenegger, J. Sehouli Tags: Regular Articles Source Type: journals

Liver X receptor alpha (LXRalpha) as a therapeutic target in chronic lymphocytic leukemia (CLL).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19875628 [PubMed - in process] (Source: Journal of Leukocyte Biology)
Source: Journal of Leukocyte Biology - October 31, 2009 Category: Hematology Authors: Christopherson KW, Landay A Tags: J Leukoc Biol Source Type: journals

Hunting for the Achilles' heel of CLLEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Blood)
Source: Blood - November 12, 2009 Category: Hematology Authors: Byrd, J. C. Tags: INSIDE BLOOD Source Type: journals

Practical Approaches in Myeloma: Optimal Management of Newly Diagnosed and Relapsed/Refractory DiseaseFriday, December 04, 2009Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Register today for this CME-certified comprehensive program on multiple myeloma presented as a Friday satellite symposium preceding the 51st ASH Annual Meeting in New Orleans. (Source: International Myeloma Foundation)
Source: International Myeloma Foundation - October 20, 2009 Category: Hematology Source Type: organizations

Newer anticoagulants in 2009Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Several newer anticoagulants are under clinical development. Recently two of them, Dabigatran etexilate/Pradaxa®. and Rivaroxaban/Xarelto® obtained marketing authorization in Europe and Canada for the prevention of thromboembolic events following major orthopedic surgery such as total hip and knee replacement. The results of Phase III clinical studies in thromboprophylaxis in major orthopedic surgery are highlighted and discussed in detail. Ongoing Phase II and III clinical trials assess their efficacy in the secondary prevention and treatment of deep vein thrombosis and pulmonary embolism, and in ...
Source: Journal of Thrombosis and Thrombolysis - October 16, 2009 Category: Hematology Tags: Journal of Thrombosis and Thrombolysis Source Type: journals

Lapalombella et al. Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells. Blood. 2008;112(13):5180-5189.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Blood)
Source: Blood - October 15, 2009 Category: Hematology Tags: ERRATA Source Type: journals

HPV Vaccines for Boys Not Cost-Effective (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vaccinating boys against human papillomavirus (HPV) is unlikely to offer good value for the money, researchers said. (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - October 9, 2009 Category: Hematology Source Type: news

Medical Articles 6/20Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Therapeutic implications of leukemia stem cell development. Information is temporarily unavailable. Tobacco use, body mass index, and the risk of leukemia and multiple myeloma: a nationwide cohort study in sweden. Information is temporarily unavailable. Repression of RUNX1 Activity by EVI1: A New Role of EVI1 in Leukemogenesis. Information is temporarily unavailable. Optimization of novel combi-molecules: Identification of balanced and mixed bcr-abl/DNA targeting properties. Information is temporarily unavailable. [Acute myelogenous leukemia with multilineage myelodysplasia, positive direct Coombs test, and elev...
Source: CML Newswire - June 20, 2007 Category: Hematology Authors: Rob Tags: Uncategorized Source Type: news

Burkitt lymphoma versus diffuse large B-cell lymphoma: a practical approachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Burkitt Lymphoma (BL) is listed in the World Health Organization (WHO) classification of lymphoid tumours as an 'aggressive B-cell non-Hodgkin's lymphoma', characterized by a high degree of proliferation of the malignant cells and deregulation of the c-MYC gene. The main diagnostic challenge in BL is to distinguish it from diffuse large B-cell lymphoma (DLBCL). While in children BL and DLBCL types probably do not differ clinically, and the differential diagnosis between BL and DLBCL may theoretically appear clear-cut, in adults daily practice shows the existence of cases that have morphological features, immunophenotypic a...
Source: Hematological Oncology - October 20, 2009 Category: Hematology Authors: Cristiana Bellan, Lazzi Stefano, De Falco Giulia, Emily A Rogena, Leoncini Lorenzo Source Type: journals

Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The mammalian target of rapamycin (mTOR) is an intracellular serine/threonine protein kinase positioned at a central point in a variety of cellular signaling cascades. The established involvement of mTOR activity in the cellular processes that contribute to the development and progression of cancer has identified mTOR as a major link in tumorigenesis. Consequently, inhibitors of mTOR, including temsirolimus, everolimus, and ridaforolimus (formerly deforolimus) have been developed and assessed for their safety and efficacy in patients with cancer. Temsirolimus is an intravenously administered agent approved by the US Food a...
Source: Journal of Hematology and Oncology - October 27, 2009 Category: Hematology Authors: RuiRong YuanAndrea KayWilliam BergDavid Lebwohl Source Type: journals