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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 28.
Pharmacotherapy in type 2 diabetes: a functional schema for drug classification.
Abstract With growing awareness that long-term hyperglycemia is directly implicated in the tissue damage characteristic of diabetes, there has been a corresponding increase in clinicians' willingness to employ intensive treatment to achieve euglycemia, which may require diabetes drugs in combination. The expanding array of drugs with different mechanisms of action calls for a clear method of classification to guide rational combination therapy. Contemporary and historical literature was surveyed to document changes in awareness of toxicity from hyperglycemia and consequent changes in treatment strategy. References ...
Source: Current Diabetes Reviews - July 1, 2012 Category: Endocrinology Authors: McGill JB Tags: Curr Diabetes Rev Source Type: research
Pediatric emergency department crowding is associated with a lower likelihood of hospital admission.
Conclusions: Increasing ED crowding is associated with a lower likelihood of hospital admission and lower frequency of return visits within 48 hours. PMID: 22724551 [PubMed - in process]
Source: Accident and Emergency Nursing - July 1, 2012 Category: Emergency Medicine Authors: Michelson KA, Monuteaux MC, Stack AM, Bachur RG Tags: Acad Emerg Med Source Type: research
Cell versus protoplasm: revisionist history.
Abstract Recent investigations give reason to question anew the historical status of the 'cell theory' as the ultimate driving force in the development of our understanding of life's processes at the most fundamental level. A revisitation of critical research papers and commentaries from the 19th Century shows that the disregarded (and historically maligned) 'protoplasmic theory of life' played a more deterministic role in the early advancement of knowledge on cell structure and function. PMID: 22681391 [PubMed - in process]
Source: Cell Biology International - July 1, 2012 Category: Cytology Authors: Welch GR, Clegg JS Tags: Cell Biol Int Source Type: research
The interplay of mitochondria with calcium: An historical appraisal.
Abstract Indirect findings in the 1950s had indicated that mitochondria could accumulate Ca(2+), but only in 1961 isolated mitochondria were directly shown to take it up in a process driven by the activity of the respiratory chain or by the hydrolysis of added ATP. The uptake of Ca(2+) could be accompanied by the simultaneous uptake of inorganic phosphate, leading to the precipitation of hydroxyapatite in the matrix and to the effective buffering of the free Ca(2+) concentration in it. The uptake of Ca(2+) occurred via an electrophoretic uniporter that has been molecularly identified only recently. Ca(2+) was then ...
Source: Cell Calcium - July 1, 2012 Category: Cytology Authors: Carafoli E Tags: Cell Calcium Source Type: research
Rupture rate for patients with untreated unruptured intracranial aneurysms in South Korea during 2006-2009.
Conclusions The overview of the incidence of rupture indicates the need for a preventive strategy and future studies to prevent rupture in Asian patients with UIAs. PMID: 22519434 [PubMed - in process]
Source: Journal of Neurosurgery - July 1, 2012 Category: Neurosurgery Authors: Lee EJ, Lee HJ, Hyun MK, Choi JE, Kim JH, Lee NR, Hwang JS, Kwon JW Tags: J Neurosurg Source Type: research
Revisiting the ants of Melanesia and the taxon cycle: historical and human-mediated invasions of a tropical archipelago.
Abstract Understanding the historical evolution of biotas and the dynamics of contemporary human-mediated species introductions are two central tasks of biology. One hypothesis may address both-the taxon cycle. Taxon cycles are phases of range expansion and contraction coupled to ecological and evolutionary niche shifts. These historical invasion processes resemble human-mediated invasions in pattern and possibly mechanism, but both the existence of historical cycles and the roles of recent introductions are in question. We return to the system that originally inspired the taxon cycle-Melanesian ants-and perform no...
Source: The American Naturalist - July 1, 2012 Category: Biology Authors: Economo EP, Sarnat EM Tags: Am Nat Source Type: research
Species-specific stable isotope analysis by the hyphenation of chromatographic techniques with MC-ICPMS.
Abstract This work reviews the basis and all the existing publications on the hyphenation of chromatography-based techniques to MC-ICPMS for isotopic studies that were published until the end of 2010. A brief historical retrospective of the measurement of isotope ratios from transient signals by ICPMS with different sample introduction techniques is also included. The most important experimental parameters and data reduction strategies affecting the accurate and precise measurement of compound-specific isotope ratios by either HPLC or GC coupled to MC-ICPMS are discussed. All the applications are reported and criti...
Source: Mass Spectrometry Reviews - July 1, 2012 Category: Molecular Biology Authors: Rodríguez-González P, Epov VN, Pecheyran C, Amouroux D, Donard OF Tags: Mass Spectrom Rev Source Type: research
Out of bounds? A critique of the new policies on hyperandrogenism in elite female athletes.
Abstract In May 2011, more than a decade after the International Association of Athletics Federations (IAAF) and the International Olympic Committee (IOC) abandoned sex testing, they devised new policies in response to the IAAF's treatment of Caster Semenya, the South African runner whose sex was challenged because of her spectacular win and powerful physique that fueled an international frenzy questioning her sex and legitimacy to compete as female. These policies claim that atypically high levels of endogenous testosterone in women (caused by various medical conditions) create an unfair advantage and must be regu...
Source: The American Journal of Bioethics : AJOB - July 1, 2012 Category: Medical Ethics Authors: Karkazis K, Jordan-Young R, Davis G, Camporesi S Tags: Am J Bioeth Source Type: research
Phylogeny, ecology, and the coupling of comparative and experimental approaches.
Abstract Recent progress in the development of phylogenetic methods and access to molecular phylogenies has made comparative biology more popular than ever before. However, determining cause and effect in phylogenetic comparative studies is inherently difficult without experimentation and evolutionary replication. Here, we provide a roadmap for linking comparative phylogenetic patterns with ecological experiments to test causal hypotheses across ecological and evolutionary scales. As examples, we consider five cornerstones of ecological and evolutionary research: tests of adaptation, tradeoffs and synergisms among ...
Source: Trends in Ecology and Evolution - July 1, 2012 Category: Science Authors: Weber MG, Agrawal AA Tags: Trends Ecol Evol Source Type: research
The continuing evolution of the Langendorff and ejecting murine heart: new advances in cardiac phenotyping.
Abstract The isolated retrograde-perfused Langendorff heart and the isolated ejecting heart have, over many decades, resulted in fundamental discoveries that form the underpinnings of our current understanding of the biology and physiology of the heart. These two experimental methodologies have proven invaluable in studying pharmacological effects on myocardial function, metabolism, and vascular reactivity and in the investigation of clinically relevant disease states such as ischemia-reperfusion injury, diabetes, obesity, and heart failure. With the advent of the genomics era, the isolated mouse heart preparation ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - July 1, 2012 Category: Physiology Authors: Liao R, Podesser BK, Lim CC Tags: Am J Physiol Heart Circ Physiol Source Type: research
Identification of ancient Olea europaea L. and Cornus mas L. seeds by DNA barcoding.
Abstract The analysis of ancient DNA (aDNA) provides archaeologists and anthropologists with innovative, scientific and accurate data to study and understand the past. In this work, ancient seeds, found in the "Mora Cavorso" archaeological site (Latium, Central Italy), were analyzed to increase information about Italian Neolithic populations (plant use, agriculture, diet, trades, customs and ecology). We performed morphological and genetic techniques to identify fossil botanical species. In particular, this study also suggests and emphasizes the use of DNA barcode method for ancient plant sample analysis. Scanning ...
Source: Comptes Rendus Biologies - July 1, 2012 Category: Biology Authors: Gismondi A, Rolfo MF, Leonardi D, Rickards O, Canini A Tags: C R Biol Source Type: research
Dairy products and physical stature: a systematic review and meta-analysis of controlled trials.
In conclusion, there is moderate quality evidence that dairy products supplementation stimulate linear growth supporting hypotheses that changing levels of consumption of dairy products in the 19th and 20th centuries contributed to trends in height. PMID: 21890437 [PubMed - in process]
Source: Economics and Human Biology - July 1, 2012 Category: Biology Authors: de Beer H Tags: Econ Hum Biol Source Type: research
The health transition and biological living standards: adult height and mortality in 20th-century Spain.
Abstract This paper seeks new insights concerning the health transition in 20th century Spain by analyzing both traditional (mortality-based) and alternative (anthropometric-based) health indicators. Data were drawn from national censuses, vital and cause-of-death statistics and seven National Health Surveys dating from 1987 to 2006 (almost 100,000 subjects aged 20-79 were used to compute cohort height averages). A multivariate regression analysis was performed on infant mortality and economic/historical dummy variables. Our results agree with the general timing of the health transition process in Spain as has been...
Source: Economics and Human Biology - July 1, 2012 Category: Biology Authors: Spijker JJ, Cámara AD, Blanes A Tags: Econ Hum Biol Source Type: research
Photodynamic therapy: A review and its prospective role in the management of oral potentially malignant disorders
AbstractWith the unreliability of epithelial dysplasia as a predictor to determine the risk of future malignant development, subjectivity associated in evaluating dysplasia by pathologists and paucity of biomarkers that could accurately predict the progression risks in oral potentially malignant disorders (PMDs), eradication of the lesions appears to be the most desirable approach to minimize the risk of invasive cancer formation. Interventions, such as surgery and chemoprevention, have not shown promising long‐term results in the treatment of these lesions, and lack of guidelines and general consensus on their managemen...
Source: Oral Diseases - July 1, 2012 Category: ENT & OMF Authors: Rajan Saini, Catherine F. Poh Tags: Review Article Source Type: research
Dengue and dengue-like outbreaks in the past: the case of the Macau epidemic fever of 1874.
Abstract Historical sources abound in references to outbreaks of a disease resembling dengue fever. Medical observers reported on its rapid onset and great expansion in the population, the diversity and changeability of its clinical features and its overall mildness. In 1874, an epidemic disease with fever, rash and rheumatic pains as main symptoms broke out in the Portuguese colony of Macau, South China. It was similar to the epidemic disease which swept the colony 2 years before during the socalled dengue pandemic of 1870-1873. The 1874 epidemic disease was variously labeled by local physicians, including dengue ...
Source: Infection, Genetics and Evolution - July 1, 2012 Category: Genetics & Stem Cells Authors: Buchillet D Tags: Infect Genet Evol Source Type: research
Infectious Insecurities: H1N1 and the politics of emerging infectious disease.
Abstract Responses to the 2009 H1N1 pandemic, and criticisms of those responses, were framed by issues endemic to the meeting of 'health' and 'security' as governing domains. Offering an editorial introduction to the selection of papers in this special issue, it is suggested that existing scholarship in the emerging field of 'health security' can be categorized according to realist-advocacy, historical-analytic, problematization and critical-inequality approaches. In contributing to this literature through an event-based focus on the pandemic, the papers embrace the opportunity to examine health security architectu...
Source: Health and Place - July 1, 2012 Category: Environmental Health Authors: Barker K Tags: Health Place Source Type: research
First steps: bovine genomics in historical perspective.
This study is a review of the early years of bovine gene mapping leading up to the sequencing and assembly of the bovine genome in 2009. A historical perspective of parasexual, linkage and physical mapping is provided with a focus on the contribution of these maps to the eventual assignment and orientation of genes and sequence to cattle chromosomes. PMID: 22742498 [PubMed - in process]
Source: Animal Genetics - July 1, 2012 Category: Genetics & Stem Cells Authors: Womack JE Tags: Anim Genet Source Type: research
Graft survival rate following renal transplantation in diabetic patients.
This study is a historical cohort study, which examined the graft survival rate among 103 kidney transplant patients with diabetes. The Kaplan-Meier method was used to determine the survival rate and the log-rank test was used to compare survival curves; P-value of less than 0.05 was considered significant. The mean follow-up period of patients was 48.15 ± 31.05 months (range: 3.07-118.03 months), and the estimated nine-year graft survival rate was 84.2% (±0.045). Based on the results of the Cox regression model, age of the donor was a contributing factor to graft survival rate. In summary, the graft survival rate in our...
Source: Saudi Journal of Kidney Diseases and Transplantation - July 1, 2012 Category: Urology & Nephrology Authors: Rajaeefard AR, Almasi-Hashiani A, Hassanzade J, Salahi H Tags: Saudi J Kidney Dis Transpl Source Type: research
A clinical trial primer: Historical perspective and modern implementation.
Abstract The structure of modern clinical trials is designed to protect patient safety while generating safety and efficacy data. Safety is the primary concern, and United States regulations are shaped by a series of responses to incidents, including notable safety lapses and unethical trials. These regulations focus on 3 essential components, defined by the 1979 Belmont Report: respect for persons, beneficence, and justice. Further, the international community has formally outlined good clinical practice (GCP), which mandates that trials are designed to produce meaningful data, conform to international ethics regu...
Source: Urologic Oncology - July 1, 2012 Category: Urology & Nephrology Authors: Karsh LI Tags: Urol Oncol Source Type: research
Acetabular considerations during total hip arthroplasty for hip dysplasia.
Abstract The wide spectrum of anatomic abnormalities that characterize hip dysplasia dictate the need for different reconstructive techniques when hip replacement is required. Multiple factors such as young age and high activity level of this patient population, coupled with the increased complexity of surgery, explain the somewhat elevated historical failure rate of hip arthroplasty in DDH and emphasize the need for careful analysis of each case and selection of the most appropriate reconstruction options. One particular problem specific to acetabular reconstruction is the deficient bone stock that may limit the ...
Source: The Orthopedic Clinics of North America - July 1, 2012 Category: Orthopaedics Authors: Dapuzzo MR, Sierra RJ Tags: Orthop Clin North Am Source Type: research
Improving older trauma patients' outcomes through targeted occupational therapy and functional conditioning.
CONCLUSION. Targeted occupational therapy and FCP can improve LOS in older trauma patients. PMID: 22742691 [PubMed - in process]
Source: The American Journal of Occupational Therapy - July 1, 2012 Category: Occupational Health Authors: O'Brien L, Bynon S, Morarty J, Presnell S Tags: Am J Occup Ther Source Type: research
[Intergenerational evolution of stature in Pernambuco State, Brazil (1945-2006): 1 - descriptive aspects].
Abstract Linear regression models with random intercepts were used to describe the evolution in stature among residents in Pernambuco State, Brazil, in 2006, born from 1945 onward. From 1947 to 1987, yearly height gain was 0.23cm in adult men and 0.15cm in women. In relation to World Health Organization standard values (2006), children and adolescents showed a declining annual height deficit of -0.019 z-scores (H/A) for girls and -0.013 for boys (1987-2006). Men and women who completed 19 years of age in 1987 showed a height deficit of 5.0cm. Projecting the trends observed in 2006, adult men and women in Pernambuco...
Source: Cadernos de Saude Publica - July 1, 2012 Category: Global & Universal Authors: Figueiroa JN, Alves JG, Lira PI, Batista Filho M Tags: Cad Saude Publica Source Type: research
Passive Immunotherapeutic Strategies for the Treatment of Malignant Gliomas
This review provides historical and recent perspectives related to passive immunotherapy for high-grade gliomas. The authors discuss approaches that use lymphokine-activated killer cells, cytotoxic T lymphocytes, and monoclonal antibodies.
Source: Neurosurgery Clinics of North America - July 1, 2012 Category: Neurosurgery Authors: Daniel T. Nagasawa, Christina Fong, Andrew Yew, Marko Spasic, Heather M. Garcia, Carol A. Kruse, Isaac Yang Source Type: research
Molecular Characteristics and Pathways of Avastin for the Treatment of Glioblastoma Multiforme
This article provides historical background and current research involving the use of bevacizumab for the treatment of recurrent glioblastoma. Although bevacizumab, approved by the Food and Drug Administration, prolongs glioblastoma progression free survivial, decreases tumor vascularization, and reduces permeability of vessels, it does not seem to prolong overall survival. Despite slowed primary tumor progression, bevacizumab treatment may facilitate transformation to a more invasive phenotype. Adaptive responses, which make glioblastoma particularly resistant to various treatment modalities have been described. Conferred...
Source: Neurosurgery Clinics of North America - July 1, 2012 Category: Neurosurgery Authors: Marko Spasic, Frances Chow, Claire Tu, Daniel T. Nagasawa, Isaac Yang Source Type: research
Clinical Considerations for Regenerative Endodontic Procedures
This article summarizes historical, current, and future regenerative treatment approaches.
Source: Dental Clinics of North America - July 1, 2012 Category: Dentistry Authors: Todd M. Geisler Source Type: research
Ramstedt and the centennial of pyloromyotomy
In this year of 2012, we note a number of centennials with varying degrees of enthusiasm: the 100th anniversaries of the sinking of the Titanic in the North Atlantic, the ending of the Qing Dynasty in China, the misfire of the British expedition to the South Pole, and the first baseball game in Boston's Fenway Park among others—including one of special significance to pediatric surgeons and the thousands of babies saved because of a discovery reported in a German journal 100 years ago. In this year, the pediatric surgical community will celebrate the 100th anniversary of Conrad Ramstedt's report, “Zur Operation der ang...
Source: Journal of Pediatric Surgery - July 1, 2012 Category: Surgery Authors: Anthony Shaw Tags: Historical Vignette Source Type: research
Acetabular Considerations During Total Hip Arthroplasty for Hip Dysplasia
The wide spectrum of anatomic abnormalities that characterize hip dysplasia dictate the need for different reconstructive techniques when hip replacement is required. Multiple factors such as young age and high activity level of this patient population, coupled with the increased complexity of surgery, explain the somewhat elevated historical failure rate of hip arthroplasty in DDH and emphasize the need for careful analysis of each case and selection of the most appropriate reconstruction options. One particular problem specific to acetabular reconstruction is the deficient bone stock that may limit the ability to place ...
Source: Orthopedic Clinics of North America - July 1, 2012 Category: Orthopaedics Authors: Michele R. Dapuzzo, Rafael J. Sierra Source Type: research
Should the definition of “sleep hygiene” be antedated of a century? A historical note based on an old book by Paolo Mantegazza, rediscovered
This article intends to demonstrate that the concept of sleep hygiene was developed many years before, thanks to the pioneering work of Paolo Mantegazza, a scientist and a professor in the Medical School of the University of Pavia, Italy. After presenting briefly the history of the University of Pavia and illustrating the profile of Paolo Mantegazza, the article presents the original book published by Mantegazza in 1864 (second edition in 1865). The authors report extensive citations of Mantegazza’s original book dealing with sleep hygiene. Mantegazza’s indications, compared with Hauri’s rules show important sim...
Source: Neurological Sciences - June 29, 2012 Category: Neurology Tags: Neurological Sciences Source Type: research
Is the combination of Cetuximab with chemo-radiotherapy regimens worthwhile in the treatment of locally advanced head and neck cancer? A review of current evidence
Abstract: The administration of Cetuximab in combination with radiotherapy and chemotherapy has shown clear survival improvements within the locally advanced and the relapsed/metastatic settings respectively. These results have provided the clinical rational for the inclusion of Cetuximab into chemo-radiation regimens. Trials assessing the combination of Cetuximab with induction chemotherapy, concomitant chemo-radiotherapy or both are reviewed. Taken together, their results suggest that the addition of Cetuximab is promising in trials of induction chemotherapy, showing almost uniformly response rates higher than historical...
Source: Critical Reviews in Oncology Hematology - June 29, 2012 Category: Cancer & Oncology Authors: Gianmauro Numico, Pierfrancesco Franco, Antonella Cristofano, Fernanda Migliaccio, Silvia Spinazzé, Nicola Silvestris, Domenico Cante, Piera Sciacero, Maria Rosa La Porta, Franco Girelli, Umberto Ricardi Source Type: research
Undifferentiated Altered Mental Status: A Late Presentation of Toxic Acetaminophen Ingestion
We describe a case of acetaminophen-induced acute liver failure that was diagnosed and treated prior to obtaining definitive historical or laboratory information about the etiology. The physical exam finding of scleral icterus in this case was a key element to rapid identification and treatment of this life-threatening condition. A discussion of appropriate N-acetylcysteine treatment for acute liver failure and acetaminophen intoxication is included.
Source: Experimental Diabetes Research - June 28, 2012 Category: Endocrinology Source Type: research
Making the Improbable Probable: Communication across Models of Medical Practice
This article draws upon elements of Habermas’s theory of communicative action in order to suggest the kind of pluralogue that is required for stakeholders in modern medicine to benefit more from publicly conversing with each other than speaking alone or using debate to argue against each other. This reasoned perspective has lessons for all discourse when deep value-based and epistemological differences cannot be easily adjudicated. Content Type Journal ArticleCategory Original ArticlePages 1-14DOI 10.1007/s10728-012-0214-3Authors Stephen Buetow, Department of General Practice and Primary Health Care, University ...
Source: Health Care Analysis - June 28, 2012 Category: Health Management Tags: Health Care Analysis Source Type: research
Screening for lung cancer using low-dose spiral CT: 10 years later, state of the art
Abstract Ten years after the first papers on this subject, this editorial represents a brief review on lung cancer screening with low-dose spiral CT. The aim is to present the main theoretical and practical problems related to lung cancer screening, the historical background and results of observational studies and the main ongoing randomised controlled trials. In particular, the National Lung Screening Trial (NLST), which was interrupted early, is discussed. The opinion of the authors is that too many questions are still awaiting an answer. Content Type Journal ArticleCategory Chest Radiology / Radiolo...
Source: La Radiologia Medica - June 28, 2012 Category: Radiology Tags: La Radiologia Medica Source Type: research
The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: Background and Consensus Recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology.
Abstract Abstract The terminology for human papillomavirus (HPV)-associated squamous lesions of the lower anogenital tract has a long history marked by disparate diagnostic terms derived from multiple specialties. It often does not reflect current knowledge of HPV biology and pathogenesis. A consensus process was convened to recommend terminology unified across lower anogenital sites. The goal was to create a histopathologic nomenclature system that reflects current knowledge of HPV biology, optimally uses available biomarkers, and facilitates clear communication across different medical specialties. The Lower Ano...
Source: Archives of Pathology and Laboratory Medicine - June 28, 2012 Category: Laboratory Medicine Authors: Darragh TM, Colgan TJ, Cox JT, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC, Members Of The Last Project Work Groups Tags: Arch Pathol Lab Med Source Type: research
Reliability of Indicators of Decline in Abundance.
Abstract Although there are many indicators of endangerment (i.e., whether populations or species meet criteria that justify conservation action), their reliability has rarely been tested. Such indicators may fail to identify that a population or species meets criteria for conservation action (false negative) or may incorrectly show that such criteria have been met (false positive). To quantify the rate of both types of error for 20 commonly used indicators of declining abundance (threat indicators), we used receiver operating characteristic curves derived from historical (1938-2007) data for 18 sockeye salmon ...
Source: Conservation Biology - June 28, 2012 Category: Biology Authors: Porszt EJ, Peterman RM, Dulvy NK, Cooper AB, Irvine JR Tags: Conserv Biol Source Type: research
Vanadium pentoxide: Use of relevant historical control data shows no evidence for a carcinogenic response in F344/N rats.
Abstract The National Toxicology Program (NTP) chronic inhalation bioassay of vanadium pentoxide (V(2)O(5)) produced "clear" evidence of lung tumors in B6C3F1 mice, but only "some" and "equivocal" evidence in male and female F344/N rats, respectively. No significant pairwise differences or trends with V(2)O(5) concentration in male or female rat poly-3-adjusted tumor incidence were reported. The "some" and "equivocal" evidence descriptors arose from comparisons of V(2)O(5)-exposed group incidence rates with NTP-2000- and NIH-07-fed historical control (HC) group incidence ranges. NTP acknowledged that use of data fr...
Source: Regulatory Toxicology and Pharmacology : RTP - June 28, 2012 Category: Toxicology Authors: Starr TB, Macgregor JA, Ehman KD, Nikiforov AI Tags: Regul Toxicol Pharmacol Source Type: research
Prospective study of erythropoietin use on quality of life and cost effectiveness in acute myeloid leukemia and allogeneic hematopoietic stem cell transplantation patients
CONCLUSIONS:ESAs have a clinical and economic benefit on Hb recovery, could improve a patient's QoL, and lead to a significant reduction in number of RBC transfusions with no effect on survival. Cancer 2012. © 2012 American Cancer Society.
Source: Cancer - June 28, 2012 Category: Cancer & Oncology Authors: Mauricette Michallet, Karine Goldet, Mohamad Sobh, Stéphane Morisset, Youcef Chelghoum, Xavier Thomas, Fiorenza Barraco, Sophie Ducastelle, Hélène Labussière, Catherine Renzullo, Carole Paillet, Christine Pivot, Perrine Badol‐Van Straaten, Angelique Tags: Original Article Source Type: research
NIH Image to ImageJ: 25 years of image analysis
Eliceiri For the past 25 years NIH Image and ImageJ software have been pioneers as open tools for the analysis of scientific images. We discuss the origins, challenges and solutions of these two programs, and how their history can serve to advise and inform other software projects.
Source: Nature Methods - June 28, 2012 Category: Research Authors: Caroline A SchneiderWayne S RasbandKevin W Eliceiri Tags: Historical Commentary Source Type: research
Cephalic Arch Stenosis in Autogenous Haemodialysis Fistulas: Treatment With the Viabahn Stent-Graft
Conclusion The use of the Viabahn stent-graft in the management of CAS is technically feasible and, in this small series, showed patency rates that compare favorably with historical data of angioplasty and bare stents. Content Type Journal ArticleCategory Clinical InvestigationPages 1-7DOI 10.1007/s00270-012-0433-xAuthors Andrew Shawyer, Radiology Department, The Royal London Hospital, London, UKNicos I. Fotiadis, Radiology Department, The Royal Marsden NHS Foundation Trust, Royal Marsden Hospital, London, SW3 6JJ UKGirish Namagondlu, Renal Medicine Department, The Royal London Hospital, London, UKAr...
Source: CardioVascular and Interventional Radiology - June 27, 2012 Category: Radiology Tags: CardioVascular and Interventional Radiology Source Type: research
The paraty artisanal fishery (southeastern Brazilian coast): ethnoecology and management of a social-ecological system (SES)
This study intends to give recommendations to the management of Paraty fishery in Brazil through an interplay of local and scientific knowledge. In particular, the objectives are the following: 1) to describe the Paraty fishery; 2) to compare the fishermen's local ecological knowledge with recorded fish landings and previous studies in Paraty; 3) to combine the data on local fishing and on local/Caicara livelihoods with the SES (social-ecological systems) Model. The methods include a systematic survey of fishing in Tarituba and Praia Grande, which are located in the northern end and the central part of the Paraty municipal...
Source: Journal of Ethnobiology and Ethnomedicine - June 27, 2012 Category: Complementary Medicine Authors: Alpina BegossiSvetlana SalyvonchykVinicius NoraPriscila LopesRenato Silvano Source Type: research
Social Determinants of Infant Mortality in a Historical Swedish Cohort
Conclusions: Our findings of determinants of neonatal and post‐neonatal mortality in 1915–1929 are strikingly consistent with results from contemporary cohorts. On the other hand, contrary to most recent findings, there is no evidence of a LBW paradox in this historical cohort.
Source: Paediatric and Perinatal Epidemiology - June 27, 2012 Category: Perinatology & Neonatology Authors: Ulla Sovio, Amanda Dibden, Ilona Koupil Source Type: research
Effects of georeferencing effort on mapping monkeypox case distributions and transmission risk
Conclusions: The importance of careful georeferencing cannot be overlooked, despite it being a time- and labor-intensive process. Investment in archival storage of primary disease-occurrence data is merited, and improved digital gazetteers are needed to support public health mapping activities, particularly in developing countries, where maps and geographic information may be sparse.
Source: International Journal of Health Geographics - June 27, 2012 Category: Global & Universal Authors: R Ryan LashDarin CarrollChristine HughesYoshinori NakazawaKevin KaremInger DamonA Townsend Peterson Source Type: research
All Psychoanalysis is Local
This article discusses the idea that psychoanalysis, like politics, is based in the “local”. Although there are universal aspects of human nature reflected in psychoanalysis, such as the method and the basic technique, there is great diversity in those who practice, train and work in particular environments and historical epochs. This article examines the development of psychoanalytic institutes and institutions as freestanding rather than university based. It discusses psychoanalytic training and the implications of the top‐down foundation of the International Psychoanalytical Association as an organization that ult...
Source: Psychotherapy and Politics International - June 27, 2012 Category: Psychiatry & Psychology Authors: Douglas Kirsner Tags: Research Article Source Type: research
Housing Instability among People Who Inject Drugs: Results from the Australian Needle and Syringe Program Survey
Abstract High rates of substance dependence are consistently documented among homeless people, and are associated with a broad range of negative outcomes among this population. Investigations of homelessness among drug users are less readily available. This study examined the prevalence and correlates of housing instability among clients of needle syringe programs (NSPs) via the Australian NSP Survey, annual cross-sectional seroprevalence studies among NSP attendees. Following self-completion of a brief, anonymous survey and provision of a capillary blood sample by 2,396 NSP clients, multivariate logistic re...
Source: Journal of Urban Health - June 26, 2012 Category: Health Management Tags: Journal of Urban Health Source Type: research
The top cited clinical research articles on sepsis: a bibliometric analysis
Conclusions: Our bibliometric analysis provides a historical perspective on the progress of clinical research on sepsis. Articles originating from the United States and published in high-impact journals are most likely to be cited in the field of sepsis research.
Source: Critical Care - June 26, 2012 Category: Intensive Care Authors: Tianzhu TaoXiaohong ZhaoJingsheng LouLulong BoFei WangJinbao LiXiaoming Deng Source Type: research
Global cellular regulation including cardiac function by post-translational protein arginylation
In this issue a very significant contribution to cardiology describing critical roles of ATE1 appears by Kurosaka et al. . In view of this paper, as the discoverers of ATE1, we have been asked to contribute an article (editorial) regarding ATE1 (enzyme which transfers arginine from arginyl tRNA to protein acceptors). This short article consists of three sections: 1) a historical anecdote describing how ATE1 was discovered; 2) its possible role in aging and cellular transformation, and most importantly; 3) its role in the development and maintenance of cardiac activity. The last section has direct bearing to the Kurosaka et al. paper.
Source: Journal of Molecular and Cellular Cardiology - June 25, 2012 Category: Cytology Authors: Hideko Kaji, Akira Kaji Tags: Editorials Source Type: research
Ubi irritatio, ibi affluxus: a 19th century perspective on haemodynamic brain activity
Abstract: The impact of cognitive operations on haemodynamic activity in the human brain is a cornerstone of modern cognitive neuroscience. This essay presents an early speculation about why there is increased blood flow following cognitive operations: Emil Harleß, a 19th century German physiologist, proposed that this blood flow responds to irritations caused by “the will” in order to restore homeostasis. Peculiar from a modern perspective, this speculation shows how neuroscientific concepts – and corresponding perspectives on cognitive function – have changed over the centuries.
Source: Cortex - June 25, 2012 Category: Neuroscience Authors: Roland Pfister, Katharina A. Schwarz, Markus Janczyk Tags: Historical Papers Source Type: research
Language Planning for the 21st Century: Revisiting Bilingual Language Policy for Deaf Children
For over 25 years in some countries and more recently in others, bilingual education involving sign language and the written/spoken vernacular has been considered an essential educational intervention for deaf children. With the recent growth in universal newborn hearing screening and technological advances such as digital hearing aids and cochlear implants, however, more deaf children than ever before have the potential for acquiring spoken language. As a result, the question arises as to the role of sign language and bilingual education for deaf children, particularly those who are very young. On the basis of recent rese...
Source: Journal of Deaf Studies and Deaf Education - June 25, 2012 Category: Audiology Authors: Knoors, H., Marschark, M. Tags: none Source Type: research
Smoking behavior of Mexicans: patterns by birth-cohort, gender, and education
Conclusion Mexico’s development may have triggered forces that decrease smoking, such as the spread of health information. Although smoking rates are falling, projections suggest that they will be persistently high for several future generations. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00038-012-0376-7Authors Rebekka Christopoulou, Department of Policy Analysis and Management, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853, USADean R. Lillard, Department of Policy Analysis and Management, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY...
Source: International Journal of Public Health - June 24, 2012 Category: Global & Universal Tags: International Journal of Public Health Source Type: research
Pharmacokinetics and safety of 6 % hydroxyethyl starch 130/0.4 in healthy male volunteers of Japanese ethnicity after single infusion of 500 ml solution
Conclusion Single administration of a 500 ml solution of 6 % HES 130/0.4 was confirmed to be safe and tolerable in healthy male Japanese subjects. A rapid renal excretion was observed within 24 h after drug administration, accounting for 96 % of the total amount excreted. A comparison with pharmacokinetic data derived from Caucasians did not reveal significant differences to Japanese and confirmed the good tolerability in both ethnic groups. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00540-012-1430-6Authors Michiaki Yamakage, Department of Anesthe...
Source: Journal of Anesthesia - June 23, 2012 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: research
Rising to the challenge of health care reform with entrepreneurial and intrapreneurial nursing initiatives.
This article provides a global perspective on evolving nursing roles for innovation in health care. A historical overview of entrepreneurship and intrapreneurship is offered. Included also is discussion of a social entrepreneurship approach for nursing, settings for nurse entre/intrapreneurship, and implications for research and practice. PMID: 22686113 [PubMed - in process]
Source: Online Journal of Issues in Nursing - June 22, 2012 Category: Nursing Authors: Wilson A, Whitaker N, Whitford D Tags: Online J Issues Nurs Source Type: research