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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 31.

Medical results of preparticipation examination in adolescent athletes
Conclusion Eligibility for competitive sports is restricted in only 5.5% of adolescent athletes at age 12. Eligibility refusals are rare. However, recommendations for therapy and prevention are frequent, mainly regarding the musculoskeletal system. In spite of time and cost consumption, adolescent preparticipation before entering a career in high-performance sports is supported.
Source: British Journal of Sports Medicine - June 1, 2012 Category: Sports Medicine Authors: Mayer, F., Bonaventura, K., Cassel, M., Mueller, S., Weber, J., Scharhag-Rosenberger, F., Carlsohn, A., Baur, H., Scharhag, J. Tags: Physiotherapy, Musculoskeletal syndromes, Physiotherapy Original articles Source Type: research

Lung Cancer and Elemental Carbon Exposure in Trucking Industry Workers
Conclusions: Lung cancer mortality in trucking industry workers increased in association with cumulative exposure to EC after adjustment for negative confounding by employment duration.
Source: EHP-in-Press - June 1, 2012 Category: Environmental Health Authors: Eric Garshick et al. Source Type: research

Metabolic markers or conditions preceding Parkinson's disease: A case‐control study
AbstractSeveral metabolic markers or conditions have been explored as possible risk or protective factors for Parkinson's disease (PD); however, results remain conflicting. We further investigated these associations using a case–control study design. We used the medical records–linkage system of the Rochester Epidemiology Project to identify 196 subjects who developed PD in Olmsted County, Minnesota, from 1976 through 1995. Each incident case was matched by age (±1 year) and sex to a general population control. We reviewed the complete medical records of cases and controls in the medical records–linkage system to ab...
Source: Movement Disorders - June 1, 2012 Category: Neurology Authors: Rodolfo Savica, Brandon R. Grossardt, J. Eric Ahlskog, Walter A. Rocca Tags: Research Article Source Type: research

Animal Biowarfare Research: Historical Perspective and Potential Future Attacks
SummaryA biological attack on livestock or poultry could result in the loss of valuable animals, costs related to the containment of outbreaks and the disposal of carcasses, lost trade and other economic effects involving suppliers, transporters, distributors and restaurants; however, it is not possible to secure all livestock, and livestock are much less well guarded than human targets. Thus, the vulnerability of the livestock industry to the introduction of biological agents varies for the following reasons: (i) the majority of lethal and contagious biological agents are environmentally resilient, endemic in foreign coun...
Source: Zoonoses and Public Health - May 31, 2012 Category: Infectious Diseases Authors: Jung‐Yong Yeh, Jee‐Yong Park, Yun Sang Cho, In‐Soo Cho Tags: REVIEW ARTICLE Source Type: research

Innovation and Innovators: Does It Take 10,000 Hours?
I would like to talk this afternoon about innovations and innovators and what might be common themes for both. Innovation in surgery has a rich tradition, and the interest and enthusiasm to innovate has never been greater. The combination of new ideas and hands-on applications is a central tenet of surgery and can explain the historical success of surgeons as innovators, as well as the progress that the innovations have created.
Source: The Journal of Hand Surgery - May 31, 2012 Category: Surgery Authors: Jesse B. Jupiter, Jillian S. Gruber Tags: Founder's Lecture Source Type: research

Structure and Age Jointly Influence Rates of Protein Evolution
We report that previously observed structural correlations also hold within each age group – including relationships between solvent accessibility, designabililty, and evolutionary rates. However, age also plays a crucial role: age modulates the relationship between solvent accessibility and rate. Additionally, younger proteins, despite being less designable, tend to evolve faster than older proteins. We show that previously reported relationships between age and rate cannot be explained by structural biases among age groups. Finally, we introduce a knowledge-based potential function to study the stability of proteins th...
Source: PLoS Computational Biology - May 31, 2012 Category: Biology Authors: Macarena Toll-Riera et al. Source Type: research

Fifty years of Weibel–Palade bodies: the discovery and early history of an enigmatic organelle of endothelial cells1
Summary. In 1962, a rod‐shaped cytoplasmic organelle of endothelial cells, later called the Weibel–Palade body, was serendipitously discovered by electron microscopy. It contains a set of parallel tubules and is wrapped in a membrane. Subsequent studies in the following decades established the unique localization of this organelle in endothelial cells of all vertebrates studied, meaning that it could serve as a marker of endothelial cells in tissue cultures. However, these studies did not reveal its functional significance, except for an indication that it could be related to an undefined thromboplastic substance. T...
Source: Journal of Thrombosis and Haemostasis - May 31, 2012 Category: Hematology Authors: E. R. WEIBEL Tags: HISTORIC REVIEW Source Type: research

Gene therapy for Leber congenital amaurosis: advances and future directions
Conclusions Initial safety studies indicated promising results of subretinal delivery of viral vector with subclinical immunologic or surgical sequelae. Overall, these initial studies demonstrate that viral vector gene therapy results are very promising, safe, and effective. Future studies measuring potential improvement in photoreceptor function may rely on recent advances in retinal imaging and electrophysiologic testing. Content Type Journal ArticleCategory Review ArticlePages 1-12DOI 10.1007/s00417-012-2028-2Authors Robert B. Hufnagel, Department of Pediatrics, Division of Pediatric Ophthalmolo...
Source: Graefe's Archive for Clinical and Experimental Ophthalmology - May 30, 2012 Category: Opthalmology Tags: Graefe's Archive for Clinical and Experimental Ophthalmology Source Type: research

Sorafenib or sunitinib as postoperative adjuvant therapy for Chinese patients with locally advanced clear cell renal cell carcinoma at high risk for disease recurrence.
CONCLUSIONS: Targeted adjuvant therapy postoperatively with sorafenib or sunitinib in patients with CC-RCC who are at a high risk for disease recurrence was well tolerated and effective in reducing the rate of CC-RCC recurrence in these patients. This study is an attempt to assess the utility of adjuvant tyrosine kinase inhibitors (TKIs) after surgery for renal carcinoma. The apparently improved outcomes, compared with a historical control population, are of sufficient interest to support the continuation of an ongoing randomized clinical trial to validate the hypothesis. PMID: 22658883 [PubMed - as supplied by publisher]
Source: Urologic Oncology - May 30, 2012 Category: Urology & Nephrology Authors: Zhao J, Zhu Y, Zhang C, Wang X, He H, Wang H, Wu Y, Zhou W, Shen Z Tags: Urol Oncol Source Type: research

Tioguanine in the treatment of refractory coeliac disease – a single centre experience
ConclusionsTioguanine appears to be a convenient drug for the treatment of refractory coeliac disease type I based on higher histological and similar clinical response rates as compared with historical conventional therapies.
Source: Alimentary Pharmacology and Therapeutics - May 30, 2012 Category: Drugs & Pharmacology Authors: G. J. Tack, D. P. Asseldonk, R. L. J. Wanrooij, A. A. Bodegraven, C. J. Mulder Tags: Original Article Source Type: research

Efficacy of olanzapine long-acting injection in patients with acutely exacerbated schizophrenia: an insight from effect size comparison with historical oral data
Conclusions: Patients treated acutely with olanzapine LAI showed a similar pattern of improvement to that seen historically with oral olanzapine. With the exception of injection-related adverse events, the efficacy and tolerability profile of olanzapine LAI is similar to oral olanzapine.Trial RegistrationClinicalTrials.gov ID; URL: http//www.clinicaltrials.gov/: NCT00088478; ClinicalStudyResults.org ID; URL: http://www.clinicalstudyresults.org/: 917, 978, 982, and 5984.
Source: BMC Psychiatry - Latest articles - May 30, 2012 Category: Psychiatry Authors: Holland DetkeFangyi ZhaoMichael Witte Source Type: research

Alcohol licensing in Scotland: a historical overview
Conclusion Scotland has developed alcohol policies several times addressing long‐standing licensing weaknesses throughout the United Kingdom. Some Scottish alcohol policies have later become the norm in England and Wales.
Source: Addiction - May 30, 2012 Category: Addiction Authors: James Nicholls Source Type: research

Treating Peripheral Arterial Disease Percutaneously with Atherectomy
Section: Original Contribution Issue Number: Volume 24 - Issue 6 - June 2012 Author(s): Bryan G. Schwartz, MD1, Robert A. Kloner, MD, PhD1,2, Steven Burstein, MD3, Christina Economides, MD3, Guy S. Mayeda, MD3 Abstract: Purpose. To determine clinical outcomes of patients who underwent percutaneous revascularization (PR) with multiple devices. Methods. PR cases at a private, tertiary referral hospital were reviewed retrospectively. Limb salvage and patency rates were calculate...
Source: The Journal of Invasive Cardiology - May 29, 2012 Category: Cardiology Authors: hmpeditor Tags: Original Contribution Source Type: research

Anatomic hepatectomy as a definitive treatment for hepatolithiasis: a cohort study
Conclusions: Anatomic liver resection is an effective treatment in selected patients with hepatolithiasis and is associated with low morbidity and no mortality. At longterm follow‐up, anatomic hepatectomy in these patients was associated with a lower rate of recurrence.
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - May 29, 2012 Category: Gastroenterology Authors: Nicolás Jarufe, Eduardo Figueroa, César Muñoz, Fabrizio Moisan, Julian Varas, José R. Valbuena, Claudia Bambs, Jorge Martínez, Fernando Pimentel Source Type: research

[News] New treatment options in advanced bladder cancer
In a multicentre phase 3 trial of 360 patients with muscle-invasive bladder cancer, British researchers compared radiation therapy alone against radiation and synchronous chemotherapy with fluorouracil and mitomycin C and found that patients given the combination lived longer than did those on radiation alone. Moreover, patients assigned to combination therapy lived as long as did historical controls who had cystectomy, the gold standard. At 2 years, rates of locoregional disease-free survival were 67% for combination therapy and 54% for patients receiving radiation alone, and at 5 years, overall survival was 48% versus 35%, respectively.
Source: The Lancet Oncology - May 29, 2012 Category: Cancer & Oncology Authors: Vicki Brower Tags: News Source Type: research

Interaction of Nitrate and Folate on the Risk of Breast Cancer Among Postmenopausal Women.
Abstract Ingested nitrate can be endogenously reduced to nitrite, which may form N-nitroso compounds, known potent carcinogens. However, some studies have reported no or inverse associations between dietary nitrate intake and cancer risk. These associations may be confounded by a protective effect of folate, which plays a vital role in DNA repair. We evaluated the interaction of dietary and water nitrate intake with total folate intake on breast cancer risk in the Iowa Women's Health Study. Dietary intake was assessed at study baseline. Nitrate intake from public water was assessed using a historical database on Io...
Source: Nutrition and Cancer - May 29, 2012 Category: Cancer & Oncology Authors: Inoue-Choi M, Ward MH, Cerhan JR, Weyer PJ, Anderson KE, Robien K Tags: Nutr Cancer Source Type: research

ORGAN EXTRACTS AND THE DEVELOPMENT OF PSYCHIATRY: HORMONAL TREATMENTS AT THE MAUDSLEY HOSPITAL 1923–1938
This article explores the way in which Maudsley doctors justified these treatments by tying together psychological theories of the unconscious with experimental data drawn from laboratory studies of human organs. It explores the logic behind these treatments and examines beliefs about their efficacy. The connection between this historical episode and current research in endocrinology and psychology is explored.
Source: Journal of the History of the Behavioral Sciences - May 29, 2012 Category: Psychiatry & Psychology Authors: BONNIE EVANS, EDGAR JONES Tags: Original Article Source Type: research

Brains, tools, innovation and biogeography in crows and ravens
Conclusions: Our study supports monophyly of the genus Corvus and further demonstrates the directionand timing of colonization from the area of origin in the Palaearctic to other continents andarchipelagos. The Caribbean was probably colonized from North America, although someNorth American ancestor may have gone extinct, and the Pacific was colonized multipletimes from Asia and Australia. We did not find a correlation between relative brain size, tooluse, innovative feeding strategies and dispersal success. Hence, we propose that all crows andravens have relatively large brains compared to other birds and thus the potenti...
Source: BMC Evolutionary Biology - Latest articles - May 29, 2012 Category: Molecular Biology Authors: Knud JønssonPierre-Henri FabreMartin Irestedt Source Type: research

Breakthrough: Arthur Blakemore and Arthur Voorhees, Jr
In 1912, the Nobel Prize in medicine was given to Alexis Carrel, recognizing his research achievements in operations on blood vessels and the transplantation of organs. He was not a clinical surgeon and did not take care of patients. Benefits to mankind were postponed 5 decades. One challenge he could not solve was to replace the aorta with a functioning graft.
Source: Journal of Vascular Surgery - May 28, 2012 Category: Surgery Authors: Sheldon Marvin Levin Tags: Historical vignettes in vascular surgery Source Type: research

Effects of Hyul-Bu-Chuke-Tang on Erythrocyte Deformability and Cerebrovascular CO2 Reactivity in Normal Subjects
Conclusions. We demonstrated that HCEt improved erythrocyte deformability and CVR. Our findings suggest that an improvement in erythrocyte deformability contributes to HCEt’s effect on cerebral microcirculation.
Source: Journal of Biomedicine and Biotechnology - May 28, 2012 Category: Biotechnology Source Type: research

Impact of Pharmacist-Managed Erythropoiesis-Stimulating Agents Clinics for Patients With Non–Dialysis-Dependent CKD
Conclusions: Relative to usual care, pharmacist-managed clinics provided improved quality of ESA dosing and monitoring for patients with NDD-CKD.
Source: American Journal of Kidney Diseases - May 28, 2012 Category: Urology & Nephrology Authors: Sherrie L. Aspinall, Francesca E. Cunningham, Xinhua Zhao, Joy S. Boresi, Ivy Q. Tonnu-Mihara, Kenneth J. Smith, Roslyn A. Stone, Chester B. Good, ESA Clinic Study Group Tags: Pathogenesis and Treatment of Kidney Disease Source Type: research

Glutathione S-transferase Pi expression predicts response to adjuvant chemotherapy for stage C colon cancer: a matched historical control study
Expression levels of Glutathione S-transferase Pi (GST Pi) are associated with overall survival of patients with stage C colon cancer and identify patients that would benefit from adjuvant therapy after resection, independently of genotype.
Source: BMC Cancer - May 28, 2012 Category: Cancer & Oncology Authors: Lucy JankovaGraham RobertsonCharles ChanKing TanMaija Kohonen-CorishCaroline FungCandice ClarkeBetty LinMark MolloyPierre ChapuisLes BokeyOwen DentStephen Clarke Source Type: research

From adaptive behavior to human cognition: a review of Enaction
Critics of the paradigm of enaction have long argued that enactive principles will be unable to account for the traditional domain of orthodox cognitive science, namely "higher-level" cognition and specifically human cognition. Moreover, even many of the paradigm’s "lower-level" insights into embodiment and situatedness appear to be amenable to a functionalist reinterpretation. In this review, I show on the basis of the recently published collection of papers, Enaction, that the paradigm of enaction has (a) a unique foundation in the notion of sense-making that places fundamental limits on the scope of functionalist ...
Source: Adaptive Behavior - May 28, 2012 Category: Nursing Authors: Froese, T. Tags: Articles Source Type: research

A Historical Perspective on Sepsis.
Abstract In North America, approximately 700,000 cases of sepsis occur each year, with mortality ranging between 30% and 50%. The American Journal of Pathology has featured numerous articles on the topic, revealing mechanistic insights gleaned from both experimental rodent models and human sepsis. Nonetheless, there remains urgent need to determine the basis for sepsis-related complications and how they can be avoided, as well as how they can be most effectively treated once recognized. This Historical Perspective reviews what we currently understand about the mechanisms of sepsis, as well as the barriers that rema...
Source: The American Journal of Pathology - May 26, 2012 Category: Pathology Authors: Ward PA, Bosmann M Tags: Am J Pathol Source Type: research

Entrevista con la Profesora Marta Shuare
This article explores the study of emotions in the Vigotski work, listing some texts that demonstrate his underlying conception of emotion before the main publishing about this subject, Emotions Theory, written between 1931 and 1933, and left unfinished by the author due to his death. This book, with the recuperation of the philosophic Cartesian base in Psychologies of emotions, introduces the predominant naturalism in Psychological science in the early twentieth century. Vigotsky analyses the need to rescue the dialectic between biological and cultural factors in the emotions constitution, to conceive them in terms of the...
Source: Psicologia em Estudo - May 25, 2012 Category: Psychiatry & Psychology Source Type: research

A zona de desenvolvimento próximo na análise de Vigotski sobre aprendizagem e ensino
This article explores the study of emotions in the Vigotski work, listing some texts that demonstrate his underlying conception of emotion before the main publishing about this subject, Emotions Theory, written between 1931 and 1933, and left unfinished by the author due to his death. This book, with the recuperation of the philosophic Cartesian base in Psychologies of emotions, introduces the predominant naturalism in Psychological science in the early twentieth century. Vigotsky analyses the need to rescue the dialectic between biological and cultural factors in the emotions constitution, to conceive them in terms of the...
Source: Psicologia em Estudo - May 25, 2012 Category: Psychiatry & Psychology Source Type: research

Emotions theory in Vigotski
This article explores the study of emotions in the Vigotski work, listing some texts that demonstrate his underlying conception of emotion before the main publishing about this subject, Emotions Theory, written between 1931 and 1933, and left unfinished by the author due to his death. This book, with the recuperation of the philosophic Cartesian base in Psychologies of emotions, introduces the predominant naturalism in Psychological science in the early twentieth century. Vigotsky analyses the need to rescue the dialectic between biological and cultural factors in the emotions constitution, to conceive them in terms of the...
Source: Psicologia em Estudo - May 25, 2012 Category: Psychiatry & Psychology Source Type: research

Notes on the constitution of the subject, subjectivity and language
Este artigo discorre sobre a constituição do sujeito e da subjetividade na abordagem sócio-histórica, trazendo para discussão a questão da linguagem e produção de sentido em autores contemporâneos estudiosos de Vygotsky. O estudo é teórico e contextualiza a elaboração conceitual da obra de Vygotsky, a qual é marcada pela complexidade e inacabamento, condições que geram diversidades nas/das interpretações entre os autores. Busca-se explicitar e compreender as diferentes noções de sujeito e de produção de sentido entre eles. Para tanto são levadas em conta as contribuições de González Rey na sua arg...
Source: Psicologia em Estudo - May 25, 2012 Category: Psychiatry & Psychology Source Type: research

Adjustments between cohabiting parents and adult children: boundary and transgression
O objetivo deste trabalho é investigar a relação entre pais e filhos adultos coabitantes no ambiente doméstico familiar e sublinhar os aspectos transformadores dessa dimensão interativa. Empreendemos uma discussão teórica interdisciplinar, incluindo autores como Singly, Giddens, Berger e Luckman. Pesquisamos esse universo por meio de um estudo de campo, realizando entrevistas semiestruturadas com oito famílias cariocas de classe média. Foram entrevistadas, separadamente e depois em conjunto, quatro díades mãe-filho, três díades mãe-filha e uma díade pai-filha. Entre os temas que emergiram da análise dos dad...
Source: Psicologia em Estudo - May 25, 2012 Category: Psychiatry & Psychology Source Type: research

The thinking on the practical activity: implications in the pedagogical process
O estudo apresenta uma síntese teórica sobre a lógica e as formas de pensamento na atividade prática como decorrentes das relações entre o homem e a realidade objetiva e suas implicações no processo pedagógico. Os aspectos teórico-metodológicos do estudo centram-se na psicologia histórico-cultural e no materialismo histórico-dialético. Conclui-se que os processos ativos de apropriação do conhecimento, quando não consideram as relações lógico-históricas do desenvolvimento e da constituição do psiquismo humano, criam limitações a que o pensamento e a linguagem sejam potenciados pelo processo educativ...
Source: Psicologia em Estudo - May 25, 2012 Category: Psychiatry & Psychology Source Type: research

Fostering excellence: development of a course to prepare graduate students for research on migration and health
In this study, we provide an analytic overview including course description, objectives, assignments, and specific class topics. Areas of focus include historical and theoretical considerations; determinants of immigrant health; refugee health; cultural competence and cultural safety; research challenges, approaches, and skills; policy‐relevant research; and educational imperatives in the health and related disciplines. Salient research is introduced in each of these classes. While Canada is the main focus, comparative data are provided and there is relevance for nurse‐researchers in other immigrant‐receiving countries.
Source: Nursing Inquiry - May 25, 2012 Category: Nursing Authors: Linda Ogilvie, Gina Higginbottom, Elizabeth Burgess‐Pinto, Christina Murray Tags: Review Source Type: research

What is a nurse? Is there an international consensus?
Conclusion: Until proper consensus is reached on what a nurse is and does, any skill mix or clinical role developments will only have limited international relevance, especially in OECD countries. If nursing qualifications are to be valid even across the European Union, then recommended standards such as those of the ICN, must be specified in terms of what different categories of nurses actually can do, and their responsibilities and roles within that scope of practice. Standardization of definitions of categories of nurse internationally should reduce confusion and promote better understanding of patterns of nurse staf...
Source: International Nursing Review - May 25, 2012 Category: Nursing Authors: E.J. Currie, R.A. Carr‐Hill Source Type: research

Targeted fluconazole prophylaxis for high-risk very low birth weight infants
Conclusion Targeted fluconazole prophylaxis in VLBW infants is effective in preventing fungal infections without increasing the risk of BSI among low-risk infants. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00431-012-1760-2Authors Asaph Rolnitsky, Neonatal Intensive Care Unit, Schneider Children’s Medical Center of Israel, 14 Kaplan Street, Petah Tikva, Israel 49202Itzhak Levy, Infectious Disease Unit, Schneider Children’s Medical Center of Israel, Petah Tikva, IsraelLea Sirota, Neonatal Intensive Care Unit, Schneider Children’s Medical Center of Israel, 14 Kaplan Street, Petah T...
Source: European Journal of Pediatrics - May 25, 2012 Category: Pediatrics Tags: European Journal of Pediatrics Source Type: research

State tobacco revenues compared with tobacco control appropriations--United States, 1998-2010.
Abstract In 1999, CDC published Best Practices for Comprehensive Tobacco Control, which outlined the elements of an evidence-based state tobacco control program and provided a recommended state funding range to substantially reduce tobacco-related disease, disability, and death. Best Practices recommended that states invest a combined $1.6-$4.2 billion annually in such programs and subsequently updated that recommendation to $3.7 billion annually in 2007. To analyze states' historical investments in tobacco control and calculate the amount of funding necessary to achieve Best Practices recommendations, CDC tracked ...
Source: MMWR Morb Mortal Wkl... - May 25, 2012 Category: Epidemiology Authors: Centers for Disease Control and Prevention (CDC) Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Vaccination therapy for non-small-cell lung cancer: review of agents in phase III development
The historical results of cancer vaccination for non-small-cell lung cancer (NSCLC) were disappointing. In the current decade, however, new insights in the interaction between tumours and the immune system have led to the development of immunotherapy as a fundamentally new concept for the treatment of NSCLC. Modern NSCLC vaccine strategies rely on better identification of antigenic targets, addition of strong immunoadjuvants, and use of more efficient delivery systems. These treatments have convincingly demonstrated to elicit potent immune responses and have shown promising efficacy signals and excellent tolerability in ph...
Source: Annals of Oncology - May 25, 2012 Category: Cancer & Oncology Authors: Decoster, L., Wauters, I., Vansteenkiste, J. F. Tags: reviews Source Type: research

Appropriate Use Criteria for Echocardiography: New Applications for a New Era of Utilization
Appropriate Use Criteria (AUC) for a variety of cardiac imaging procedures were developed in response to the dramatic increase in the performance of and expenditures on cardiac imaging over the last two decades. The cumulative growth in medical diagnostic imaging of 85% (2000-2009), including a near doubling in the volume of transthoracic echocardiography (TTE), has exceeded the growth of any other physician service. This increase in utilization has raised questions from governmental and private payers about potential misuse and overuse of cardiac imaging procedures and placed cardiac diagnostic imaging in the vortex of th...
Source: Journal of the American Society of Echocardiography - May 24, 2012 Category: Cardiology Authors: R. Parker Ward Tags: Editorial Comment Source Type: research

Estimation of historical effective population size using linkage disequilibria with marker data
This study considers the impact of several developments on the estimation of Ne using both simulated and equine high‐density single‐nucleotide polymorphism data, when Ne is assumed to be constant a priori and when it is not. In all models, estimates of Ne were highly sensitive to thresholds imposed upon minor allele frequency (MAF) and to a priori assumptions on the expected r2 for adjacent markers. Where constant Ne was assumed a priori, then estimates with the lowest mean square error were obtained with MAF thresholds between 0.05 and 0.10, adjustment of r2 for finite sample size, estimation of a [the limit for r2 as...
Source: Journal of Animal Breeding and Genetics - May 24, 2012 Category: Genetics & Stem Cells Authors: L.J. Corbin, A.Y.H. Liu, S.C. Bishop, J.A. Woolliams Tags: ORIGINAL ARTICLE Source Type: research

A historical perspective of PCL bracing
Conclusions There is limited information evaluating the specific effectiveness of PCL knee braces. A properly designed PCL brace should apply correct anatomic joint forces that vary with the knee flexion angle and also provide adjustability to satisfy the demands of various activities. No braces are currently available with biomechanical evidence that satisfies these requirements. Level of evidence IV. Content Type Journal ArticleCategory KneePages 1-7DOI 10.1007/s00167-012-2048-9Authors Kyle S. Jansson, Department of BioMedical Engineering, Steadman Philippon Research Institute, V...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - May 24, 2012 Category: Orthopaedics Tags: Knee Surgery, Sports Traumatology, Arthroscopy Source Type: research

Blinded Measure of Trendelenburg Angle in Pelvic Robotic Surgery
Conclusions: A mean Trendelenburg angle of 28.0 degrees was adequate to complete most gynecologic robotic surgical procedures when compared with historical control angle of 40 degrees.
Source: The Journal of Minimally Invasive Gynecology - May 24, 2012 Category: OBGYN Authors: Claire Gould, Thomas Cull, Ying Xing Wu, Blake Osmundsen Tags: Original Articles Source Type: research

How unique is continuity of care? A review of continuity and related concepts
Conclusions. The identified themes appear to be core elements of care to patients. Thus, it may be valuable to develop an instrument to measure these three common themes universally. In the patient-centred medical home, such an instrument might turn out to be an important quality measure, which will enable researchers and policy makers to compare care settings and practices and to evaluate new care interventions from the patient perspective.
Source: Family Practice - May 24, 2012 Category: Primary Care Authors: Uijen, A. A., Schers, H. J., Schellevis, F. G., van den Bosch, W. J. H. M. Tags: REVIEWS Source Type: research

Does the African-American–White Mortality Gap Persist After Playing Professional Basketball? A 59-Year Historical Cohort Study
Conclusions: The African-American–white mortality gap for males is largely ameliorated (1.5 years vs. 6.1 years) in professional basketball but still persists.
Source: Annals of Epidemiology - May 23, 2012 Category: Epidemiology Authors: Tyler Lawler, Frank Lawler, Jack Gibson, Rachael Murray Source Type: research

Historical influence of predation pressure on escape by Podarcis lizards in the Balearic Islands
Island tameness (reduced escape behaviour on islands where prey have experienced prolonged relaxation of predation pressure) is known in several taxa, although the relationships between recent predation pressure and escape on islands are poorly known. We investigated escape by numerous populations exposed to differing predation pressure of two sister species of Podarcis lizards in the Balearic Islands. Our main findings are that flight initiation distance was greater in Podarcis pityusensis than Podarcis lilfordi and increased as predation pressure increased in P. pityusensis. Island tameness led to extinction of P. li...
Source: Biological Journal of the Linnean Society - May 23, 2012 Category: Research Authors: WILLIAM E. COOPER JR, VALENTÍN PÉREZ‐MELLADO Source Type: research

Frequency of Genital Involvement in Women with Oral Lichen Planus in Southern Iran
Conclusion. In spite of low genital involvement possibly due to inadequate patient population, lack of follow-up visits, and contribution of genetic or ethnic factors, for conservative patient care, women with the oral lichen planus in particular those having some relevant genital symptoms, should preferably be referred for careful vulvovaginal examination. Multicenter cohort studies on women of different geographical regions or ethnicities who have genital lichen planus alone or in combination with other common sites are encouraged.
Source: Journal of Cancer Epidemiology - May 23, 2012 Category: Epidemiology Source Type: research

Representations of the subject 'woman' and the politics of abortion: an analysis of South African newspaper articles from 1978 to 2005.
Abstract A key element in cultural and gender power relations surrounding abortion is how women who undergo an abortion are represented in public talk. We analyse how women were named and positioned, and the attendant constructions of abortion, in South African newspaper articles on abortion from 1978 to 2005, a period during which there were radical political and legislative shifts. The name 'woman' was the most frequently used (70% of articles) followed by 'girl/teenager/child' (25%), 'mother' (25%), 'patient' (11%) and 'minor' (6%). The subject positionings enabled by these names were dynamic and complex and wer...
Source: Culture, Health and Sexuality - May 23, 2012 Category: Global & Universal Authors: Macleod CI, Feltham-King T Tags: Cult Health Sex Source Type: research

Immunotherapies in Dermatologic Disorders
Treatment modalities and therapeutic response experience support the use of immunotherapy in the treatment of many diseases in all fields of medicine. The aim of this article is to conduct and present a review of literature on the use of immunotherapy in the treatment of skin diseases analyzing scientific literature available up to January 2012. Studies that presented evidence-based data were selected. The article discusses how blocking or reverting the effect of a specific immunologic disequilibrium can treat dermatoses and intends to transfer a large amount of immunotherapy knowledge into a historical perspective for phy...
Source: Medical Clinics of North America - May 23, 2012 Category: Primary Care Authors: Robyn S. Fallen, Collin R. Terpstra, Hermenio C. Lima Source Type: research

Victorian illness narratives and their meanings: a book review of Tuberculosis and the Victorian Literary Imagination
Katherine Byrne's new book Tuberculosis and the Victorian Literary Imagination is a welcome addition to the recent medical humanities scholarship on the interrelationship between literature and medicine in nineteenth-century Britain. It fits well with other studies in Gillian Beer's Cambridge Studies in Nineteenth Century Literature and Culture series such as Miriam Bailin's The Sickroom in Victorian Fiction: The Art of Being Ill (1994), Pamela K Gilbert's Disease, Desire, and the Body in Victorian Women's Popular Novels (1997), and Janis McLarren Caldwell's Literature and Medicine in Nineteenth-Century Britain from Mary S...
Source: Medical Humanities - May 23, 2012 Category: Global & Universal Authors: McKechnie, C. C. Tags: Reviews Source Type: research

On the relevance of morality in social psychology: An introduction to a virtual special issue
AbstractRecently, social psychology has become central in the study of morality. This turn to morality as a topic builds on social psychologists' long‐standing interest in issues closely related to morality, such as cooperation, empathy, fairness, social norms and deviance. The present paper introduces a (virtual) special issue on morality by highlighting some of the 41 articles on “moral” or “morality” that have appeared in the European Journal of Social Psychology from 1973 to the present. The nineteen highlighted papers are organized into the main topics covered in research on morality published in EJSP: Emoti...
Source: European Journal of Social Psychology - May 23, 2012 Category: Psychiatry & Psychology Authors: Stefano Pagliaro Tags: Virtual Issue Editorial Source Type: research

Q&A: The graphic historian
Q&A: The graphic historian Nature 485, 7399 (2012). doi:10.1038/485445a Author: Jascha Hoffman New York-based author and illustrator Jonathan Fetter-Vorm makes hand-printed books on Darwin and other historical scientific subjects — including a hand-stitched treatise on surgical suturing. As he releases Trinity, a graphic history of the atomic bomb, Fetter-Vorm talks about crafting science chronicles.
Source: Nature - May 23, 2012 Category: Research Authors: Jascha Hoffman Tags: Books and Arts Source Type: research

Concurrent radiation with irinotecan and carboplatin in intermediate‐ and high‐risk rhabdomyosarcoma: A report on toxicity and efficacy from a prospective pilot phase II study
ConclusionsPreliminary results of irinotecan and carboplatin administered with concurrent RT in intermediate‐ and high‐risk RMS demonstrated favorable tolerability, efficacy, and local control. Reduced rates of acute grades 3–4 mucositis were observed when compared with historical results. Pediatr Blood Cancer © 2012 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - May 22, 2012 Category: Cancer & Oncology Authors: Kavita V. Dharmarajan, Leonard H. Wexler, Suzanne L. Wolden Tags: Research Article Source Type: research

Breakthrough: Arthur Blakemore and Arthur Voorhees
In 1912, the Nobel Prize in medicine was given to Alexis Carrel, recognizing his research achievements in operations on blood vessels and the transplantation of organs. He was not a clinical surgeon and did not take care of patients. Benefits to mankind were postponed 5 decades. One challenge he could not solve was to replace the aorta with a functioning graft.
Source: Journal of Vascular Surgery - May 22, 2012 Category: Surgery Authors: Sheldon Marvin Levin Tags: Historical vignettes in vascular surgery Source Type: research