Hospital Management Research This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 22.

A phase II study of combined fulvestrant and RAD001 (everolimus) in metastatic estrogen receptor (ER) positive breast cancer after aromatase inhibitor (AI) failure.
Conclusions: Combined everolimus with fulvestrant is feasible and has manageable toxicities in this cohort of women with metastatic ER-positive breast cancer. Detailed efficacy analysis along with updated toxicity data will be presented at the meeting.Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P2-14-05.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Croley, J., Black, E., Romond, E., Chambers, M., Waynick, S., Slone, S., Waynick, C., Stevens, M., Weiss, H., Massarweh, S. Tags: Poster Session 2 - Treatment: Endocrine Therapy - Advanced Disease Source Type: research

Understanding the complex non face-to-face interventions delivered by the clinical nurse specialists in metastatic breast cancer.
Introduction: Despite improving survival rates in breast cancer, globally one third of patients diagnosed with primary breast cancer will go onto develop metastatic breast cancer. In recent years treatment for metastatic breast cancer in the United Kingdom has moved to the ambulatory setting using treatments such as, oral chemotherapies, oral biological and bisphosphonate therapies meaning telephone consultation and clinical management, pivotal to confluent care.Research Objectives: To determine the number and complexity of incoming telephone calls, the stage of the metastatic breast cancer disease pathway for example at d...
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Warren, M., Mackie, D., Leary, A. Tags: Poster Session 2 - Psychosocial, Quality of Life, and Educational Aspects: Quality of Life - Supportive Care Source Type: research

Psycho-spiritual therapy for improving the quality of life and spiritual well-being of women with breast cancer
Conclusions: The results of this trial showed that the psycho-spiritual therapy program can improve the spiritual well-being and QOL of women with breast cancer. This program, with its ease of implementation and home practice, could be adopted in comprehensive care programs for women with breast cancer.Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P2-12-10.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Loghmani, A., Jafari, N., Zamani, A., Farajzadegan, Z., Bahrami, F., Emami, H. Tags: Poster Session 2 - Psychosocial, Quality of Life, and Educational Aspects: Quality of Life - Supportive Care Source Type: research

Perception and practice of reproductive specialists towards fertility preservation of young breast cancer patients
Conclusion Reproductive specialists recognize the needs of FP in YBC patients and are willing to participate and support care for YBC. Affiliation of reproductive specialists was related to positive attitude towards to egg preservation. Various concerns regarding FP among reproductive specialists indicate the need for evidence that supports the safety of FP for YBC patients and guidelines that facilitate the practice and communication of oncologists and reproductive specialists.Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P2-11-02.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Shimizu, C., Kato, T., Tamura, N., Asada, Y., Hiroko, B., Mizota, Y., Yamamoto, S., Fujiwara, Y. Tags: Poster Session 2 - Psychosocial, Quality of Life, and Educational Aspects: Survivorship Research Source Type: research

Development and validation of ClinicoMolecular Triad Classification (CMTC), a platform for breast cancer (BC) prognostic and predictive gene signature portfolios.
This study aimed to validate the CMTC classification using an independent BC cohort.Study design/ results: RNA from fine needle aspirates were collected in a prospective BC cohort (n = 340) between 2008 and 2010 at Princess Margaret Hospital and Mount Sinai Hospital, Toronto, we included all newly diagnosed BC patients going for surgery who consented to join the study. DNA microarray analyses were carried out using genome-wide Illumina Human Ref-8 version 3 Beadarrays, which contained >24K oligonucleotide probes. After excluding tumors with low RNA yield (n = 8, success rate 97%), non-invasive cancers (n = 27), insuffic...
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Leong, W., Wang, D.-Y., Done, S., McCready, D. Tags: Poster Session 2 - Prognostic and Predictive Factors: Prognostic Factors - Clinical Source Type: research

Association between circulating tumor cells and molecular breast cancer subtypes
Conclusion: Our study suggests that presence of CTCs was more frequently found in patients with HER2+ and Luminal B subtypes. The presence of CTCs in patients with TNBC subtype was not as high as we wished. Theoretically, the positive rate of CTCs in TNBC subtype should be higher than that of others subtypes for being more aggressive histologically features and having increased potential to be invasive. One possible explanation for this might because of lacking epithelial markers expression and epithelial-mesenchyme transition (EMT) characteristics, CTCs of TNBC subtype are missed when using the standard EpCAM-based method...
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Gang, N., Haibo, W., Funian, L., Chen, L., Xiaoyi, L., Xingang, W., Zhidong, L. Tags: Poster Session 2 - Prognostic and Predictive Factors: Prognostic Factors - Clinical Source Type: research

Chemotherapy-Induced Neutropenia in Breast Cancer Patients Receiving Sequential Anthracycline and Taxane Chemotherapy: An institutional experience
Conclusions: Sequential use of EC followed by D in combination with prophylactic pegfilgrastim results in lower den expected FN rate [1]. In contrast to most published trials EC leads to significantly more neutropenias than D. However, the use of pegfilgrastim reduces both EC and D associated neutropenias grade 3 and 4 to a similar extent.References:1. Aapro, M.S., et al., 2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours. Eur J Cancer. 47(1): p. 8&nda...
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Staudigl, C., Seifert, M., Tea, M.-K., Pfeiler, G., Fink-Retter, A., Fritzer, N., Singer, C. Tags: Poster Session 1 - Treatment: Toxicities - Management Source Type: research

Higher toxicity of docetaxel for obese women with early breast cancer: lean body mass is a significant predictor of chemotherapy dose intensity reduction
Conclusion: Docetaxel is less well tolerated and the dose intensity received is lower for obese patients. The lean body mass measured by computed tomography is a new significative predictor of docetaxel dose intensity reduction in the early breast cancer.Key Words: Early breast cancer-Chemotherapy-Docetaxel-Epirubicine-Body Mass Index-Lean Body Mass-Dose Intensity-ToxicityCitation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P1-15-08.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Gouerant, S., Clatot, F., Modzlewski, R., Chaker, M., Rigal, O., Veyret, C., Leheurteur, M. Tags: Poster Session 1 - Treatment: Toxicities - Management Source Type: research

The impact of musculoskeletal toxicity on adherence to endocrine therapy in women with early stage breast cancer- observations in a non-trial setting
Conclusions: This large cohort study reports similar MSKT rates with AI therapy as reported in the literature. AIs have higher incidence of self-reported MSKTs (64%) compared to TAM (36%). Patients discontinued treatment due to MSKT significantly more with AI (22%) than TAM (14%) but adherence to AI therapy increased when treated for MSKT. These encouraging results reflect the real life experience of women exposed to ET.Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P1-15-06.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Dent, S., Campbell, M., Crawley, F., Clemons, M. Tags: Poster Session 1 - Treatment: Toxicities - Management Source Type: research

Patterns of granulocyte colony stimulating factor (G-CSF) use in elderly breast cancer (BC) patients receiving myelosuppressive chemotherapy
Conclusion: NCCN recommends PPG be used with HR regimens and older age (notably >65 yr), an important risk factor for developing severe neutropenic complications. Despite this, PPG was used for elderly breast cancer patients in only 52% of chemotherapy courses with high risk of FN and in 10% of IR courses. More than 10% of patients with a HR regimen had an FN hospitalization. Careful attention to FN risk factors, including regimen and patient age, is needed when planning treatment strategy.HR regimens: TAC (389); dose dense AC->T (345); docetaxel+trastuzumab (61); doxorubicin+docetaxel (50); doxorubicin+paciltaxel (2...
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Blaes, A., Chia, V., Solid, C., Page, J., Barron, R., Choi, M., Arneson, T. Tags: Poster Session 1 - Treatment: Toxicities - Management Source Type: research

Young age: predicts poor response rate after neoadjuvant chemotherapy in endocrine-responsive breast cancer
Conclusions: The very young age group showed lower ORR(CR+PR) to neoadjuvant chemotherapy, although there was no significant difference in pCR rate between the two age groups in HR-positive breast cancer patients. We might have to consider and revalue the chemotherapeutic role as neoadjuvant therapy in very young age, HR-positive group, since they had lower survival rate than others.Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P1-14-16.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Kim, M., Noh, D.-Y., Han, W., Moon, H.-G., Ahn, S.-K., Kim, J., Kim, T., Kim, J., Lee, J. Tags: Poster Session 1 - Treatment: Neoadjuvant Chemotherapy Source Type: research

---
Conclusions: Our results show the low level of discordance for ER and HER2 between the primary and metastatic tumor. But re-biopsy should be considered in the patients with long TTR, since it is likely to impact treatment choice. Further study is needed to determine the value of re-biopsy.Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P1-02-02.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Tags: Poster Session 1 - Detection/Diagnosis: Biopsy Techniques Source Type: research

Sentinel lymph node biopsy in breast cancer: The approach in day surgery under local anaesthesia for quality-of-life and significant cost reduction
This study was approved by an ethics committee, was discussed with all patients and informed consent was obtained.Purpose of the study is to investigate the approach in DS under LA for quality of life and significant cost reduction.Results: Six patients underwent pre-operative lymphoscintigraphy the radiotracer did not show any sentinel lymph node (SLN), in five cases we performed axillary dissection (AD). In one case of young patient who had previously been treated with chemotherapy for non-Hodgkin's lymphoma, negative positron emission tomography (PET), we performed quadrantectomy without AD. In three cases the axilla wa...
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Ricci, F., Capuano, L., Saralli, E., Di Legge, P., Violante, A., Polistena, A., Scala, T., Pacchiarotti, A., Cannas, P., Cianni, R., Fanelli, G., Bellardini, P., De Masi, C. Tags: Poster Session 1 - Detection/Diagnosis: Axillary Staging and Sentinel Nodes Source Type: research

Patterns of definitive axillary management in the era prior to reporting ACOSOG Z0011: comparison between NCCN Centers and hospitals in Michigan
Conclusions: Omission of CALND occurred frequently in women with SLN positive breast cancer cared for in both NCCN and MiBOQI institutions in advance of reporting results of ACOSOG-Z0011. This shift was seen in management of patients undergoing lumpectomy as well as mastectomy. Further study is warranted to determine the extent of durable practice changes as well as any impact on survival and local-regional control.Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P1-01-13.
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Breslin, T., Hwang, S., Mamet, R., Hughes, M., Otteson, R., Edge, S., Moy, B., Rugo, H., Wong, Y.-N., Wilson, J., Laronga, C., Weeks, J., Silver, S., Marcom, P. Tags: Poster Session 1 - Detection/Diagnosis: Axillary Staging and Sentinel Nodes Source Type: research

Factors which affect surgical management in an underinsured, county hospital population
Conclusions: Breast conservation and mastectomy with reconstruction can be achieved in a significant proportion (74%) of underscreened and underinsured patients. Patients who underwent preoperative chemotherapy were more likely to undergo breast conservation. Younger patients and patients with adequate HL were more likely to choose reconstruction after mastectomy. Patients treated by breast surgical oncologists were more likely to have breast conservation or mastectomy with reconstruction. Even in an underscreened population, presentation with metastatic disease is uncommon in patients with operable breast cancer.Citation ...
Source: Cancer Research - December 17, 2012 Category: Cancer & Oncology Authors: Komenaka, I., Olsen, L., Klemens, A., Hsu, C.-H., Nodora, J., Martinez, M., Thompson, P., Bouton, M. Tags: Poster Discussion 8 - Disparities Source Type: research

Acupuncture for Cancer-Related Fatigue in Patients With Breast Cancer: A Pragmatic Randomized Controlled Trial [Complementary Therapy]
Conclusion Acupuncture is an effective intervention for managing the symptom of CRF and improving patients' quality of life.
Source: Journal of Clinical Oncology - December 17, 2012 Category: Cancer & Oncology Authors: Molassiotis, Bardy, Finnegan-John, Mackereth, Ryder, Filshie, Ream, Richardson Tags: Supportive Care, Complementary & Alternative Medicine Complementary Therapy Source Type: research

Table of Contents
Abstract SAMHSA Issues Final Rule Allowing OTPs to Dispense Take‐Home Buprenorphine Vt. Hospital Program Manages Planned and Unexpected Growth Program to Screen Staff for Relapse Risk after DUI Tragedy Where Recovery Residences Fit in Health Care Reform Bill White ‘Retiring’ but Will Continue Work in the Field Study: Binge Eating in Teens Associated with Initiating Drug Use Resources Obituary Coming up
Source: Alcoholism and Drug Abuse Weekly - December 17, 2012 Category: Addiction Source Type: research

Post-discharge experiences of children and their families following children's surgery
In conclusion, recovery from surgery is influenced by multiple factors; overall, families and children are resilient. There is a role for health professionals to tailor and improve information provision to parents and children about post-operative recovery, including assessment and management of pain. Information should be made available that describes the experience of other families who have undergone a similar surgery, and families should be made aware of what information they need and how to access it before and after discharge.
Source: Journal of Child Health Care - December 16, 2012 Category: Pediatrics Authors: Ford, K., Courtney-Pratt, H., FitzGerald, M. Tags: Articles Source Type: research

Checking out HOK's other designs
Most college newspapers have slowed the pace of their online news sites as finals and winter break approach, so Miner Business will forego this week's summary of WNY campus news. In lieu, it's worth pointing out this recent story, updating progress on the University at Buffalo's new medical school. Renderings are not yet available, that's coming in January, so checking out architect HOK's other health-related designs around the world in an interesting exercise in the meantime. There are hospitals…
Source: bizjournals.com Health Care:Hospitals headlines - December 15, 2012 Category: Hospital Management Authors: Dan Miner Source Type: research

Senate moves bill covering fertility care for vets
The Senate passed a bill Thursday to update the Veterans Affairs Department's medical coverage for trauma to a soldier's reproductive organs, Federal News Radio reports. Nearly 2,000 service members suffered such wounds between 2003 and 2011. The legislation is estimated to cost $568 million over five years, to be covered through savings from scaling down military operations in Afghanistan and Iraq.
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Source Type: research

SLU professors get $1.8 million NIH grant to study lupus
Two Saint Louis University professors received a $1.8 million grant from the National Institutes of Health to study the physiological and biochemical functions of lupus, an autoimmune disease. Terry Moore and Anil Chauhan, who both work in the department of rheumatology at SLU, will use the funds to study the role of T-cells and immune complexes in the disease. A normal T-cell, a type of white blood cell, functions as a line of defense against infection. However, with lupus patients the body’s…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Matthew Hibbard Source Type: research

Allina's Sister Kenny to merge with Courage Center
Allina Health System's Sister Kenny Rehabilitation Institute and the Courage Center, a Twin Cities nonprofit that offers medical rehabilitation services and community recreation programs, have reached a deal to merge. The merger is expected to close in spring 2013. Who will lead the combined organization has yet to be decided, Courage Center spokesman Ryan Hoffman said. The foundations of both Sister Kenny and Courage Center are expected to merge along with the organizations. Golden Valley-based…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Katharine Grayson Source Type: research

Nashville's Healthiest Employers offer advice on workplace wellness
So you've heard about the benefits of workplace wellness programs — savings on health care premiums, reduced absenteeism, etc. — but you don't know where to begin. As part of our 2012 Healthiest Employers awards, we asked our finalists and winners so share their best advice. To see what's worked for them, check out the photo gallery to the right, which features our finalists practicing what they preach. Winners of this year's awards were announced during a luncheon Thursday at the Loews Vanderbilt…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Eric Snyder Source Type: research

Galera headquarters move demonstrates need for local venture capital
Here at BizNext we like to point out when local startups raise money, launch products or hit other milestones of success. But occasionally we also like to point out that without local investors to back the local startups, they may not remain local for much longer. For example, in the days of old when BizNext was launched (last August), we brought you a Q&A with Silicon Valley venture capitalist Henry Wong. One of the questions we asked him was what local startups had to do to make sure they…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Amir Kurtovic Source Type: research

UNC Health Care names new boss at WakeBrook
In today’s paper, I wrote about how UNC Health Care applied to add 16 inpatient beds at WakeBrook, a mental health hospital it is taking over in the new year. As part of the transition, UNC named Dr. Brian Sheitman the man to oversee the new facility. Sheitman joined UNC in 1996 and is a clinical professor in the UNC-Chapel Hill School of Medicine’s Department of Psychiatry and also is medical director of the UNC Center for Excellence in Community Mental Health. He has held various leadership…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Jason deBruyn Source Type: research

Grooming the next generation in health care
Nashville’s biggest industry is on the brink of rapid transformation. Health care, a $70 billion sector of our city that encompasses more than 250 local companies and 200,000 local jobs, faces unprecedented levels of reform, cost pressures and broadening access. Nashville is poised to take on these challenges, which is why many of the city’s top health care executives and I have signed on to spearhead the Nashville Health Care Council’s Fellows initiative, a program designed to engage, educate…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Bill Frist Source Type: research

More women choosing birthing centers, midwives as delivery alternatives
When Nashville resident Hannah Phaneuf was pregnant with her now 3-year-old son, she chose to deliver him at Vanderbilt University, choosing a midwife instead of a doctor. Nine months ago, she went even further from the traditional hospital setting and delivered her daughter in a cabin at The Farm Midwifery Center in Summertown, Tenn. “It’s a more personable level of care,” she said of her original decision. “With a midwife, you’re going to spend an hour or two talking about any fears.…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Jamie McGee Source Type: research

SimulTOF Systems raises first tranche of $6M round
Sudbury-based Virgin Instruments Corp., which does business under the name of SimulTOF Systems, has raised $1.5 million out of a potential $6 million round of equity, according to federal filings. The company makes mass spectrometry equipment for biological and clinical research, and was founded in 2006 by Chief Scientific Officer Marvin Vestal. Vestal holds more than 50 patents in the field of mass spectrometry, a method of determining masses of particles that helps to identify the chemical structures…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Don Seiffert Source Type: research

On mental health, Atkinson, Roper agree
In the past year or so, Bill Atkinson and Bill Roper have found plenty about which to disagree. When it comes to expanding mental health care, however, they seem to be on the same page. UNC Health Care, led by Roper, plans to expand a mental health hospital at WakeBrook, and Atkinson, WakeMed Health & Hospitals president and CEO, gave his full support, particularly if it helps defray some of the care that he says WakeMed has largely shouldered in Wake County. “These patients often remain in a…
Source: bizjournals.com Health Care:Hospitals headlines - December 14, 2012 Category: Hospital Management Authors: Jason deBruyn Source Type: research

Tending the job stresses of health-care providers
Doctors, nurses and other direct-care workers know that any day could bring unexpected deaths, families fighting over patient care, an unsympathetic patient or babies born too soon. Too many such days can wear on an individual and ultimately impair the care he or she delivers, some attest. “To a degree, we know what we signed up for,” says the Rev. Dale Stanley, manager of spiritual care at Sisters Hospital. “I don’t know if we knew the cumulative effect that 24/7 for five, 10, 15 years…
Source: bizjournals.com Health Care:Biotechnology headlines - December 14, 2012 Category: Biotechnology Authors: Annemarie Franczyk Source Type: research

Use of Noninsulin Antidiabetic Medications in Hospitalized Patients
This article details the different classes of noninsulin antidiabetic medications, the mechanism of action, metabolism, elimination, dose form, usual and maximum doses, contraindications, precautions, common adverse reactions, and implications for use in the hospitalized patient.
Source: Critical Care Nursing Clinics of North America - December 14, 2012 Category: Nursing Authors: Cori Kopecky Source Type: research

?Talk, talk, cry, laugh?: learning, healing and building an Aboriginal workforce to address family violence.
PMID: 23237329 [PubMed - as supplied by publisher]
Source: Australian Health Review - December 14, 2012 Category: Hospital Management Authors: Lauw ML, Spangaro J, Herring S, McNamara LD Tags: Aust Health Rev Source Type: research

The affordability of prescription medicines in Australia: are copayments and safety net thresholds too high?
PMID: 23237385 [PubMed - as supplied by publisher]
Source: Australian Health Review - December 14, 2012 Category: Hospital Management Authors: Searles A, Doran E, Faunce TA, Henry D Tags: Aust Health Rev Source Type: research

Universal access to ambulance does not increase overall demand for ambulance services in Queensland, Australia.
PMID: 23237427 [PubMed - as supplied by publisher]
Source: Australian Health Review - December 14, 2012 Category: Hospital Management Authors: Tippett VC, Toloo GS, Eeles D, Ting JY, Aitken PJ, Fitzgerald GJ Tags: Aust Health Rev Source Type: research

The hidden cost of medical student education: an exploratory study.
PMID: 23237477 [PubMed - as supplied by publisher]
Source: Australian Health Review - December 14, 2012 Category: Hospital Management Authors: Oates RK, Goulston KJ Tags: Aust Health Rev Source Type: research

Finding a living kidney donor: experiences of New Zealand renal patients.
PMID: 23237503 [PubMed - as supplied by publisher]
Source: Australian Health Review - December 14, 2012 Category: Hospital Management Authors: Martin P Tags: Aust Health Rev Source Type: research

Impact on hospital mortality of catheter removal and adequate antifungal therapy in Candida spp. bloodstream infections
Conclusions Delay in catheter withdrawal and in administration of adequate antifungal therapy was associated with increased mortality in candidaemic patients. Catheter management did not influence the prognosis of secondary non-catheter-related candidaemia.
Source: Journal of Antimicrobial Chemotherapy - December 14, 2012 Category: Microbiology Authors: Garnacho-Montero, J., Diaz-Martin, A., Garcia-Cabrera, E., Ruiz Perez de Pipaon, M., Hernandez-Caballero, C., Lepe-Jimenez, J. A. Tags: Original research Source Type: research

Methotrexate or expectant management in women with an ectopic pregnancy or pregnancy of unknown location and low serum hCG concentrations? A randomized comparison
STUDY QUESTION What is the treatment success rate of systemic methotrexate (MTX) compared with expectant management in women with an ectopic pregnancy or a pregnancy of unknown location (PUL) with low and plateauing serum hCG concentrations? SUMMARY ANSWER In women with an ectopic pregnancy or a PUL and low and plateauing serum hCG concentrations, expectant management is an alternative to medical treatment with single-dose systemic MTX. WHAT IS KNOWN AND WHAT THIS PAPER ADDS MTX is often used in asymptomatic women with an ectopic pregnancy or a PUL with low and plateauing serum hCG concentrations. These pregnancies may b...
Source: Human Reproduction - December 14, 2012 Category: Reproduction Medicine Authors: van Mello, N. M., Mol, F., Verhoeve, H. R., van Wely, M., Adriaanse, A. H., Boss, E. A., Dijkman, A. B., Bayram, N., Emanuel, M. H., Friederich, J., van der Leeuw-Harmsen, L., Lips, J. P., Van Kessel, M. A., Ankum, W. M., van der Veen, F., Mol, B. W., Haj Tags: Early pregnancy Source Type: research

Incidence and trends of heart failure admissions after coronary artery bypass grafting surgery
Conclusions Pre-operative EF is a strong predictor of HF admission within 2 years after CABG surgery. The use of beta-blockers decreased HF admission after CABG, especially in patients with EF <35%. Despite the more pronounced benefit and increasing use of beta-blockers in patients with a low EF, HF admission rates in this group of patients are rising. This suggests that more comprehensive management of factors associated with HF is necessary.
Source: European Journal of Heart Failure - December 14, 2012 Category: Cardiology Authors: Moreyra, A. E., Deng, Y., Wilson, A. C., Cosgrove, N. M., Kostis, W. J., Kostis, J. B., for the MIDAS 18 study group Tags: EPIDEMIOLOGY Source Type: research

Randomized Clinical evaluatiON of wireless fluid monitoriNg and rEmote ICD managemenT using OptiVol alert-based predefined management to reduce cardiac decompensation and health care utilization: The CONNECT-OptiVol study
Conclusion: The CONNECT-OptiVol study aims to answer whether wireless fluid monitoring integrated into RM may reduce cardiac decompensations and health care utilization in ICD patients. The results can be used to adequately power future studies evaluating the benefit of these features. Study enrollment has been completed, and follow-up is expected to be finished in September 2012.
Source: Contemporary Clinical Trials - December 13, 2012 Category: Radiology Authors: Markus Zabel, Dirk Vollmann, Lars Lüthje, Joachim Seegers, Christian Sohns, Dieter Zenker, Gerd Hasenfuss Tags: Study Design, Statistical Design, Study Protocols Source Type: research

The need for expanded monitoring of adverse events in behavioral health clinical trials
Abstract: Monitoring for possible adverse events is ethically required by Institutional Review Boards and Good Clinical Practice guidelines for all human research involving the delivery of treatment interventions in a clinical trial. The monitoring of adverse events is a well-established and routine practice for contemporary clinical trials involving medications and medical devices. However, these same guidelines have not been fully integrated into clinical trials involving the use of behavioral health interventions and psychotherapy. Most behavioral health clinical trials limit adverse event monitoring to serious adverse ...
Source: Contemporary Clinical Trials - December 13, 2012 Category: Radiology Authors: Alan L. Peterson, John D. Roache, Jeslina Raj, Stacey Young-McCaughan, for the STRONG STAR Consortium Tags: Clinical Trial Management and Optimization Source Type: research

[Diagnostic and evolutionary aspects of hemorrhagic syndromes of the newborn in Dakar.]
CONCLUSION: This study reveals the high mortality due to hemorrhagic syndromes caused by these three diseases for which prevention must be stressed. PMID: 23245867 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - December 13, 2012 Category: Pediatrics Authors: Faye BF, Sylla A, Seck M, Sall A, Toure AO, Gueye NR, Signate-Sy H, Sall MG, Sow D, Diop S Tags: Arch Pediatr Source Type: research

Factors influencing the adoption and implementation of teledentistry in the UK, with a focus on orthodontics
ConclusionsImplementing teledental applications necessitates full comprehension and consideration of the healthcare environment and also a commitment to completely integrate teledentistry within that environment. This is a process that demands strategic alignment with clinical and organizational goals, clinical engagement and strong political support. The challenges within each stakeholder group must be specifically targeted.
Source: Community Dentistry and Oral Epidemiology - December 13, 2012 Category: Dentistry Authors: Reena N. Patel, Gregory S. Antonarakis Tags: Original Article Source Type: research

The practice of adult genetics: A 7‐year experience from a single center
Abstract The purpose of our study is to familiarize the reader with genetic disorders commonly seen in adults and identify challenges and barriers that limit provision of services. We conducted a retrospective chart analysis of patients seen in the adult Genetics clinics from January 2004 to December 2010 in a metropolitan medical center consisting of an academic private clinic and a county hospital clinic. During the study period, a total of 1,552 patients (n = 1,108 private clinic patients; n = 444 county clinic patients) were evaluated and managed. Of these, 790 and 280 were new patient visits at the private cli...
Source: American Journal of Medical Genetics Part A - December 13, 2012 Category: Genetics & Stem Cells Authors: Tanya N. Eble, Sandesh C.S. Nagamani, Luis M. Franco, Sharon E. Plon, Maria Blazo, Shweta U. Dhar Tags: Research Article Source Type: research

Viability: A Cultural Calculus of Personhood at the Beginnings of Life
This article addresses birth and the recognition of personhood. It is about the calculated acts of recognition that take place at the beginnings of life when the obligation to protect and extend physical care is uncertain. It examines these dilemmas from the perspective of clinicians and scientists who assist in birth through their work with embryos, fetuses, and extremely premature infants in the United States. Through multisited ethnography and in‐depth interviews at a leading U.S. teaching hospital, this article argues that the concept of viability operates as a placeholder for the recognition of personhood at the beg...
Source: Medical Anthropology Quarterly - December 13, 2012 Category: Global & Universal Authors: Astrid Christoffersen‐Deb Source Type: research

Informal patient payments in maternity hospitals in Kiev, Ukraine
The objective of this paper is to explore the practice of informal payments for maternity care in Ukraine, specifically in cases of childbirth in Kiev maternity hospitals. The paper provides an ethnographic study on the consumers' and providers' experiences with informal payments. The results suggest that informal payments for childbirth are an established practice in Kiev maternity hospitals. The bargaining process between the pregnant woman (incl. her partner) and the obstetrician is an important part of the predelivery arrangement, including the informal payment. To deal with informal payments in Kiev maternity hospital...
Source: The International Journal of Health Planning and Management - December 13, 2012 Category: Health Management Authors: Tetiana Stepurko, Milena Pavlova, Olena Levenets, Irena Gryga, Wim Groot Tags: Research Article Source Type: research

Pattern of paediatric corneal laceration injuries in the university of port Harcourt teaching hospital, rivers state, Nigeria
Conclusion: Most eye injuries in children are preventable. In this study, the prognosis was better in those whose injuries were confined to a peripheral part of the cornea, with no other associated injury, who presented within 5 days and who did not have any intraocular infection at the time of presentation. The importance of health education, adult supervision of play and application of appropriate measures that is necessary for reducing the incidence and severity of trauma is emphasized.
Source: BMC Research Notes - December 13, 2012 Category: Research Authors: Adio OmobolanleNwachukwu Henrietta Source Type: research

Snakebite on the hand: lessons from two clinical cases illustrating difficulties of surgical indication
Snakebite is a particularly important health problem in rural areas of tropical regions. A large number of victims survive with permanent physical sequelae due to local tissue necrosis. However, necrosis may be associated with compartment syndrome especially when the bite is on the hands or feet. Herein, we describe two cases reported at a rural district hospital in Central African Republic. The present study suggests that active multidisciplinary management may improve patient prognosis while evidencing how difficult it is to decide on surgical intervention.
Source: Journal of Venomous Animals and Toxins including Tropical Diseases - December 12, 2012 Category: Tropical Medicine Source Type: research

Epidemiological investigation on envenomation: from theory to practice
A better understanding of the epidemiology of envenoming would improve care, provided that the survey is representative, reliable and accurate. Several types of surveys could help to clarify the incidence, severity, circumstances, factors and determinants of envenomations. The relevant information may be collected and analyzed from hospital records or case report forms (for retrospective studies) or established from a protocol of longitudinal observation of cases attended at health facilities during a given period (prospective study). The household survey includes interviewing all or part of the population of a locality wi...
Source: Journal of Venomous Animals and Toxins including Tropical Diseases - December 12, 2012 Category: Tropical Medicine Source Type: research

Phoenix to tax hospitals to cover uninsured patients
The city of Phoenix has passed a short-term tax on local hospitals that could garner about $200 million to help pay for uninsured people. The Arizona Republic reported the measure was passed Tuesday and could bring in $130 million, with the federal government providing $2 in matching funds for every dollar raised. The measure received support from doctors, nurses and other health care representatives.
Source: bizjournals.com Health Care:Hospitals headlines - December 12, 2012 Category: Hospital Management Source Type: research