Infectious Diseases Research
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 31.
Delayed Plasmodium falciparum clearance following
artesunate-mefloquine combination therapy in
Thailand, 1997-2007
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The paper analyses 31 drug efficacy studies over 10 years. Delayed resolution of parasitaemia increased in eastern Thailand. An important point is that treatment failure probably correlates more with resistance of mefloquine or the artemisinin partner drug rather than the delayed clearance which relates to artemisinin. The paper makes an important point about correlation of delayed clearance with treatment failure and finds little correlation.
Source: Malaria Journal - August 28, 2012 Category: Infectious Diseases Authors: Saowanit VijaykadgaAlisa AlkerWichai SatimaiJohn MacArthurSteven MeshnickChansuda Wongsrichanalai Source Type: research
Variation in apoptosis mechanisms employed by
malaria parasites: the roles of inducers, dose
dependence and parasite stages
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This is an important paper for the field of programmed cell death in malaria parasites. The authors study both chemical and ecological inducers of apoptosis, dose responses, and they also test for a variety of apoptosis markers.
Source: Malaria Journal - August 28, 2012 Category: Infectious Diseases Authors: Holly MatthewsMedhat AliVictoria CarterAnn UnderhillJennifer HuntHannah SzorHilary Hurd Source Type: research
Genetic variation in histidine rich proteins among
Indian Plasmodium falciparum population: possible
cause of variable sensitivity malaria of rapid
diagnostic tests
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The study investigated the genetic diversity of pfhrp2 in P. falciparum isolates collected from six geographical regions in India and its potential impact on the detection limit of HRP2-detecting RDT. The information on the Pfhrp2 sequence diversity in Indian parasites is of interest as this was not included in the global sequence analysis for pfhrp2 and 3.
Source: Malaria Journal - August 28, 2012 Category: Infectious Diseases Authors: Navin KumarJai SinghVeena PandeNeelima MishraBina SrivastavaRidhima KapoorNeena ValechaAnupkumar Anvikar Source Type: research
Trends in availability and prices of subsidized ACT
over the first year of the AMFm: evidence from
remote regions of Tanzania
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This paper presents results for repeated rounds of surveys of accredited drug dispensing outlets in two regions of Tanzania after the first arrival of AMFm subsidized ACT in Tanzania.
Source: Malaria Journal - August 28, 2012 Category: Infectious Diseases Authors: Prashant YadavJessica CohenSarah AlphsJean ArkedisPete LarsonJulius MassagaOliver Sabot Source Type: research
Artemisinin resistance containment project in
Thailand. II: responses to mefloquine-artesunate
combination therapy among falciparum malaria
patients in provinces bordering Cambodia
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This manuscript reports on an important effort to support containment of drug resistant malaria by improving information systems in collaboration with the Ministry of Health.
Source: Malaria Journal - August 28, 2012 Category: Infectious Diseases Authors: Wichai SatimaiPrayuth SudathipSaowanit VijakadgeAmnat KhamsiriwatcharaSurasak SawangThanapon PotithavorananAumnuyphan SangvicheanCharles DelacollettePratap SinghasivanonJaranit KaewkungwalSaranath Lawpoolsri Source Type: research
The prognostic value of schizontaemia in imported
Plasmodium falciparum malaria
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Presence of schizonts on admission was associated with a high positive predictive value for severe malaria. This may be of help to identify patients who are at risk of a more severe course than would be expected when considering peripheral parasitaemia alone.
Source: Malaria Journal - August 28, 2012 Category: Infectious Diseases Authors: Marlies van WolfswinkelMariana de Mendonça MeloKlaske Vliegenthart-JongbloedRob KoelewijnJaap van HellemondPerry van Genderen Source Type: research
High-throughput sorting of mosquito larvae for
laboratory studies and for future vector control
interventions
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One strategy for the control of pest insects has been the release of only males so that a lethal trait can be passed on. With mosquitoes a major stumbling block to the implementation of this strategie has been the ability to effectively identify and separate the sexes at an early stage of development using automated strategies. Here the authors show that this can achieved quite effectively through the combinatorial use of a dedicated FACS, fluorescent reporter genes, and promoters specific for early stages of development.
Source: Malaria Journal - August 28, 2012 Category: Infectious Diseases Authors: Eric MaroisChristina ScaliJulien SoichotChristine KapplerElena LevashinaFlaminia Catteruccia Source Type: research
In vitro antibiotic susceptibility testing of Brucella isolates from Egypt between 1999 and 2007 and evidence of probable rifampin resistance
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Background:
Brucellosis poses a significant public health problem in Mediterranean countries, including Egypt. Treatment of this disease is often empirical due to limited information on the antibiotic susceptibility profiles of Brucella spp. in this region of the world. The aim of this study was to determine the antibiotic susceptibility profiles of Brucella blood isolates in Egypt, a country endemic for brucellosis.
Methods:
Brucella spp. isolates were identified from the blood cultures of acute febrile illness (AFI) patients presenting to a network of infectious disease hospitals from 1999-2007. Minimum inhibitory concen...
Source: BioMed Central - August 28, 2012 Category: Journals (General) Authors: Mohamed Abdel-MaksoudBrent HouseMomtaz WasfyBassem Abdel-RahmanGuillermo PimentelGehan RoshdyErica Dueger Source Type: research
Actinobaculum schaalii an emerging pediatric pathogen?
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Conclusions:
A.schaalii is an emerging pathogen in adults and children. Colonization and subsequent infection seem to be influenced by the age of the patient. In young children with high suspicion of UTI who use diapers or in children who have known abnormalities of their urogenital tract, infection with A. schaalii should be considered and empiric antimicrobial therapy chosen accordingly.
Source: BMC Infectious Diseases - August 28, 2012 Category: Infectious Diseases Authors: Petra ZimmermannLivia BerlingerBenjamin LinigerSebastian GruntPhilipp AgyemanNicole Ritz Source Type: research
A study of the prevalence and risk factors leading to HIV infection among a sample of street children and youth of Kathmandu
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Conclusions:
This sample of street children and youth of Kathmandu has a nearly 20-fold higher prevalence of HIV infection than the general population of Nepal (0.39%). The children and youth engage in number of high risk behaviours, including intravenous drug use, putting them at significant risk of contracting HIV and other sexually transmitted infections.
Source: AIDS Research and Therapy - August 28, 2012 Category: Infectious Diseases Authors: Dibesh KarmacharyaDongmei YuSameer DixitRajesh RajbhandariBhawana SubediSonu ShresthaSulochana ManandharSusan Santangelo Source Type: research
Influence of HTLV-1 on the clinical, microbiologic and immunologic presentation of tuberculosis
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Conclusion:
While the increased susceptibility for tuberculosis infection in HTLV-1 infected subjects may be related to impairment in TNF-alpha production, the severity of tuberculosis in co-infected patients may be due to the enhancement of the Th1 inflammatory response, rather than in their decreased ability to control bacterial growth.
Source: BMC Infectious Diseases - August 28, 2012 Category: Infectious Diseases Authors: Maria de Lourdes BastosSilvane SantosAnselmo SouzaBrooke FinkmooreOhana BispoTasso BarretoIngrid CardosoIana BispoFlavia BastosDaniele PereiraLee RileyEdgar Carvalho Source Type: research
Emergence of extensively drug-resistant Acinetobacter baumannii complex over 10 years: Nationwide data from the Taiwan Surveillance of Antimicrobial Resistance (TSAR) program
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Conclusions:
This longitudinal multicenter surveillance program revealed significant increase and nationwide emergence of IRABC and XDRABC in Taiwan over the years. This study also identified factors associated with IRABC and XDRABC to help guide empirical therapy and at-risk groups requiring more intense interventional infection control measures with focused surveillance efforts.
Source: BMC Infectious Diseases - August 28, 2012 Category: Infectious Diseases Authors: Shu-Chen KuoShan-Chwen ChangHui-Ying WangHui-Fen LaiPei-Chen ChenYih-Ru ShiauI-Wen HuangTsai-Ling Lauderdale Source Type: research
Review of Crimean Congo Hemorrhagic Fever Infection in Kosova in 2008 and 2009: Prolonged Viremias and Virus Detected in Urine by PCR
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
The Nonnucleoside Reverse Transcription Inhibitor MIV-160 Delivered from an Intravaginal Ring, But Not from a Carrageenan Gel, Protects Against Simian/Human Immunodeficiency Virus-RT Infection
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AIDS Research and Human Retroviruses , Vol. 0, No. 0.
Source: AIDS Research and Human Retroviruses - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Evaluation of the efficacy and safety of biapenem against pneumonia in the elderly and a study on its pharmacokinetics
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Abstract Although biapenem is used in the treatment of pneumonia, the clinical data on elderly patients are yet insufficient. Therefore,
the purpose of this study was evaluating the efficacy and safety of biapenem against pneumonia in the elderly and its pharmacokinetics.
The subjects were patients 65 years of age or older with pneumonia. Biapenem (300 mg) was administered once to three times
per day. For some cases, the drug concentrations in plasma were measured chronologically. The clinical efficacy was evaluated
in reference to the improvement in subjective symptoms and objective opinion. The p...
Source: Journal of Infection and Chemotherapy - August 27, 2012 Category: Infectious Diseases Tags: Journal of Infection and Chemotherapy Source Type: research
The first complete genome sequences of clinical isolates of human coronavirus 229E
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We present
here the first full-length genome sequence of two clinical isolates. Each encoded gene was compared to Inf-1. In general,
little sequence changes were noted, most could be attributed to genetic drift, since the clinical isolates originate from
2009 to 2010 and VR740 from 1962. Hot spots of substitutions were situated in the S1 region of the Spike, the nucleocapsid
gene, and the non-structural protein 3 gene, whereas several deletions were detected in the 3′UTR. Most notable was the difference
in genome organization: instead of an ORF4A and ORF4B, an intact ORF4 was present in clinical isolates.
Conte...
Source: Virus Genes - August 27, 2012 Category: Genetics & Stem Cells Tags: Virus Genes Source Type: research
An unusual presentation of a common infection
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Abstract A 40-year-old Ghanaian woman presented with fever and exanthema. She had anemia, leukopenia, increased erythrocyte sedimentation
rate (ESR), creatinin kinase, lactate dehydrogenase (LDH), and liver enzymes. She was diagnosed with schistosomiasis and was
cured with praziquantel. During the following years, she developed polymyositis, chronic nephritis, and life-threatening perimyocarditis.
High numbers of Epstein–Barr virus (EBV)-encoded RNA copies were demonstrated in CD8+ T-lymphocytes from endomyocardial biopsies.
There was no evidence of any underlying immunosuppression or an EBV-related malign...
Source: Infection - August 27, 2012 Category: Infectious Diseases Tags: Infection Source Type: research
Microbial biofilm formation and catheter-associated bacteriuria in patients with suprapubic catheterisation
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Conclusions This study provides the first analysis of MSPCC. Indwelling time increases, whereas antibiotic prophylaxis decreases the risk
of MSPCC. The spectrum of pathogens is comparable to the one obtained from urethral catheter biofilms. Urine specimens could
not demonstrate the microbial diversity of MSPCC. SPCs are not preferable to urethral catheters to reduce CAB. Whether the
risk of CA-UTI could be minimised by SPCs remains to be clarified.
Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00345-012-0930-1Authors
Gernot Bonkat, Department of Urology, University Hosp...
Source: World Journal of Urology - August 27, 2012 Category: Urology & Nephrology Tags: World Journal of Urology Source Type: research
Post-surgical hemorrhagic infarction of the adrenal gland as the first clinical manifestation of antiphospholipid syndrome after 43 years of antibody-positivity
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We report on a male patient who tested positive for antiphospholipid antibodies for 43 years without thromboembolic manifestation
of antiphospholipid syndrome (APS). He has been followed up in a prospective cohort study since 2001. Following his second
hip replacement surgery, the patient developed acute adrenal failure due to bilateral hemorrhagic infarction. Prophylactic
anticoagulation, surgery, or an immunological reaction to blood transfusion may have triggered this late and unusually located
primary manifestation of APS in our patient.
Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.1007...
Source: Modern Rheumatology - August 27, 2012 Category: Rheumatology Tags: Modern Rheumatology Source Type: research
Antibiotics Linked to Weight Gain
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From Nature magazine [More]
Source: Scientific American - Official RSS Feed - August 27, 2012 Category: Science Tags: Health,Health,Pharmaceuticals,More Science,Ethics,Infectious Diseases,Biology,Society & Policy Source Type: research
Antibiotics Linked to Weight Gain in Mice
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From Nature magazine [More]
Source: Scientific American - Official RSS Feed - August 27, 2012 Category: Science Tags: Health,Health,Pharmaceuticals,More Science,Ethics,Infectious Diseases,Biology,Society & Policy Source Type: research
Hand Hygiene: State-of-the-Art Review With Emphasis on New Technologies and Mechanisms of Surveillance
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Abstract Hand hygiene (HH) is an important measure in infection prevention to decrease transmission of microbial pathogens; however,
HH compliance by health-care workers (HCWs) remains suboptimal. One of the principal recommendations of current guidelines
is that waterless, alcohol-based hand rubs are the preferred method for HH in most situations, due to the superior efficacy
of these agents in rapidly reducing bacterial counts on hands and their ease of use. Improving HH compliance is a good quality
indicator for hospital patient safety programs. Observers can follow HCWs to perform direct HH observations;...
Source: Current Infectious Disease Reports - August 27, 2012 Category: Infectious Diseases Tags: Current Infectious Disease Reports Source Type: research
Commentary
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This article serves as a reminder that in addition to ultrasonographic probes being a potential vector for bacteria, nonsterile ultrasonographic gel may also transmit pathogens. It is important for emergency physicians to recognize the risk of transmitting infection by ultrasonographic examination and the methods that can be used to prevent this transmission. The risk is intensified when the probe and gel contact mucus membranes and nonintact skin.
Source: Annals of Emergency Medicine - August 27, 2012 Category: Emergency Medicine Authors: Daniel Weingrow Tags: Infectious Disease Source Type: research
Pseudomonas aeruginosa Respiratory Tract Infections Associated With Contaminated Ultrasound Gel Used for Transesophageal Echocardiography—Michigan, December 2011–January 2012
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[Centers for Disease Control and Prevention. Pseudomonas aeruginosa respiratory tract infections associated with contaminated ultrasound gel used for transesophageal echocardiography—Michigan, December 2011–January 2012. MMWR Morb Mortal Wkly Rep. 2012;61:262-264.]
Source: Annals of Emergency Medicine - August 27, 2012 Category: Emergency Medicine Authors: Centers for Disease Control and Prevention Tags: Infectious Disease Source Type: research
Recent Advances (2011-2012) in Technology-Delivered Interventions for People Living with HIV
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Abstract Technology is rapidly advancing and becoming a cost effective option for intervention delivery particularly for isolated and
hard to reach populations, such as people living with HIV/AIDS. A systematic review was conducted to identify recent technology
based interventions for people living with HIV. The review yielded 12 studies that were grouped by the health behavior that
it addressed and then the type of technology utilized. The majority of studies reviewed focused on medication adherence and
used several different technologies to deliver the intervention including SMS/text messaging, cell phones...
Source: Current HIV/AIDS Reports - August 27, 2012 Category: Infectious Diseases Tags: Current HIV/AIDS Reports Source Type: research
Interferon-based Therapy for e-antigen Negative Chronic Hepatitis B Virus Infection
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Abstract The prevalence of the hepatitis B e antigen (HBeAg)-negative form of chronic hepatitis B (CHB) has increased over the years
and is generally more difficult to treat. Pegylated interferon (PEG-IFN) offers a durable response, finite treatment duration
and absence of viral resistance. On the other hand, the risk of viral relapse for patients discontinuing nucleos(t)ide analogues
remains a major concern for this form of treatment, raising the spectre of drug resistance and safety with long-term use.
PEG-IFN remains one of the first-line drugs for a select group of CHB patients, and with its dual immunom...
Source: Current Hepatitis Reports - August 27, 2012 Category: Infectious Diseases Tags: Current Hepatitis Reports Source Type: research
No Serologic Evidence for Zoonotic Canine Respiratory Coronavirus Infections among Immunocompetent Adults
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This study supports the premise that humans are not at risk for CRCoV infections; however, infrequent cross‐species transmission of CRCoV cannot be ruled out.
Source: Zoonoses and Public Health - August 27, 2012 Category: Infectious Diseases Authors: W. S. Krueger, G. L. Heil, G. C. Gray Tags: ORIGINAL ARTICLE Source Type: research
Editorial Board
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Source: International Journal of Infectious Diseases - August 27, 2012 Category: Infectious Diseases Source Type: research
Evaluation of the Infectiousness to Mice of Soil Contaminated with Yersinia pestis-Infected Blood
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Relationship Between Crimean-Congo Hemorrhagic Fever Virus Strains Circulating in Iran and Turkey: Possibilities for Transborder Transmission
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Nanospheres Encapsulating Anti-Leishmanial Drugs for Their Specific Macrophage Targeting, Reduced Toxicity, and Deliberate Intracellular Release
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Detection of Chikungunya Virus in Wild Populations of Aedes albopictus in Kerala State, India
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Evaluation of Chimeric Yellow Fever 17D/Dengue Viral Replication in Ticks
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
The 31-kDa Antigen of Angiostrongylus cantonensis Comprises Distinct Antigenic Glycoproteins
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Zoonotic Vector-Borne Bacterial Pathogens in California Mountain Lions (Puma concolor), 1987–2010
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Freshwater Clams As Bioconcentrators of Avian Influenza Virus in Water
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Seroprevalence of Crimean Congo Hemorrhagic Fever Virus in Ijara District, Kenya
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Rickettsia Species in Ticks Removed from Humans in Istanbul, Turkey
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Vector-Borne and Zoonotic Diseases , Vol. 0, No. 0.
Source: Vector-Borne and Zoonotic Diseases - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Hepatitis D in the Middle East and North Africa (MENA): Update and Challenges Ahead
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Abstract Hepatitis D virus (HDV) is a defective RNA virus and its life cycle is dependent on hepatitis B virus (HBV). Worldwide, it
is estimated that 15 to 20 million individuals are HDV- infected representing approximately 5 % of the 350 million cases of
HBV chronically- infected individuals. The belief that HDV is under control is far from true. Studies from Europe have clearly
shown that HDV reservoirs have been maintained via import from Southern or Eastern Europe, and from endemic areas such as
countries of the Middle East and North Africa (MENA region). The current review highlights the underestim...
Source: Current Hepatitis Reports - August 27, 2012 Category: Infectious Diseases Tags: Current Hepatitis Reports Source Type: research
Preventing Perinatal Transmission of HBV: An Australian Perspective
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This article provides an up-to-date account of the available evidence
of the safety and efficacy of ante partum antiviral therapy options and a management plan is proposed. Mothers with HBV infection
and high viral load should have the opportunity to consider this evidence. Post-partum HBV flares are common but usually mild.
It is unclear whether post partum flares are best ignored till they settle or if they represent an opportunity for intervention
to increase the chance of HBV clearance.
Content Type Journal ArticleCategory Global Perspectives: Australia (W Sievert, Section Editor)Pages 1-7DOI 10.1007/s11901-01...
Source: Current Hepatitis Reports - August 27, 2012 Category: Infectious Diseases Tags: Current Hepatitis Reports Source Type: research
CXCR4-Tropic, But Not CCR5-Tropic, Human Immunodeficiency Virus Infection Is Inhibited by the Lipid Raft-Associated Factors, Acyclic Retinoid Analogs, and Cholera Toxin B Subunit
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AIDS Research and Human Retroviruses , Vol. 0, No. 0.
Source: AIDS Research and Human Retroviruses - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Short Communication Emerging Transmitted HIV Type 1 Drug Resistance Mutations Among Patients Prior to Start of First-Line Antiretroviral Therapy in Middle and Low Prevalence Sites in China
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AIDS Research and Human Retroviruses , Vol. 0, No. 0.
Source: AIDS Research and Human Retroviruses - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Presence of High-Risk Human Papillomavirus Genotype and Human Immunodeficiency Virus DNA in Anal High-Grade and Low-Grade Squamous Intraepithelial Lesions
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AIDS Research and Human Retroviruses , Vol. 0, No. 0.
Source: AIDS Research and Human Retroviruses - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Transmitted Antiretroviral Drug Resistance in Newly HIV-Infected and Untreated Patients in Ségou and Bamako, Mali
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AIDS Research and Human Retroviruses , Vol. 0, No. 0.
Source: AIDS Research and Human Retroviruses - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
Safety, Tolerability, and Efficacy of KP-1461 as Monotherapy for 124 Days in Antiretroviral-Experienced, HIV Type 1-Infected Subjects
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AIDS Research and Human Retroviruses , Vol. 0, No. 0.
Source: AIDS Research and Human Retroviruses - August 27, 2012 Category: Infectious Diseases Tags: article Source Type: research
A live weight–heart girth relationship for accurate dosing of east African shorthorn zebu cattle
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Abstract The accurate estimation of livestock weights is important for many aspects of livestock management including nutrition, production
and appropriate dosing of pharmaceuticals. Subtherapeutic dosing has been shown to accelerate pathogen resistance which can
have subsequent widespread impacts. There are a number of published models for the prediction of live weight from morphometric
measurements of cattle, but many of these models use measurements difficult to gather and include complicated age, size and
gender stratification. In this paper, we use data from the Infectious Diseases of East Africa calf c...
Source: Tropical Animal Health and Production - August 27, 2012 Category: Veterinary Research Tags: Tropical Animal Health and Production Source Type: research
Atypical mycobacterial spondylitis as a challenging differential diagnosis to metastatic disease of the spine: a case report
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We present a case involving a tumor-like
disseminated MAC infection with spondylitis in a 68-year-old man whose symptoms started with severe lower back pain and fever.
Treatment for malignancy was performed initially but soon stopped after tissue proving MAC infection. Symptoms then improved
dramatically after a four-drug combined anti-nontuberculous mycobacteria treatment.
Content Type Journal ArticleCategory Up-to date Review and Case ReportPages 1-5DOI 10.1007/s00590-012-1068-yAuthors
Chien-Shun Wang, Department of Orthopedics and Traumatology, Veterans General Hospital-Taipei, National Yang-Ming University Sc...
Source: European Journal of Orthopaedic Surgery and Traumatology - August 27, 2012 Category: Orthopaedics Tags: European Journal of Orthopaedic Surgery & Traumatology Source Type: research
A delivery system of linezolid to enhance the MRSA osteomyelitis prognosis: in vivo experimental assessment
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Abstract
Staphylococcus aureus, a major responsible microorganism of osteomyelitis, represents a challenge to treat because of the poor penetration of antibiotics
in bone and increasing minimum inhibitory concentrations (MICs) to glycopeptides. The calcium-deficient apatites (CDA), closer
to the biological components found in bone and other calcified tissues, have osteoconductive properties. So, to process severe
osseous infections, CDA can be used to deliver in the infectious site antibiotics like linezolid. The acute experimental osteomyelitis
due to methicillin-resistant Staphylococcus aureus (MRSA) was...
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 27, 2012 Category: Microbiology Tags: European Journal of Clinical Microbiology & Infectious Diseases Source Type: research
Implantable electrophysiologic cardiac device infections: a risk factor analysis
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Abstract The risk of cardiac device infection (CDI) is rising significantly, with several risk factors identified. The purpose of this
study is to determine the rate of CDI at our center and to assess the associated risk factors, in order to define appropriate
measures to prevent this complication. We retrospectively reviewed all cases of patients with CDI at St. George Hospital between
February 1999 and July 2010. Each case was matched with three controls. We performed a descriptive and bivariate analysis
to identify significant risk factors. Eighteen case patients and 54 control subjects met the inclusion ...
Source: European Journal of Clinical Microbiology and Infectious Diseases - August 27, 2012 Category: Microbiology Tags: European Journal of Clinical Microbiology & Infectious Diseases Source Type: research
Cytomegalovirus ventriculoencephalitis with compartmentalization of antiviral-resistant cytomegalovirus in a T cell–depleted haploidentical peripheral blood stem cell transplant recipient
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We describe a case of cytomegalovirus (CMV) ventriculoencephalitis and retinitis with compartmentalization of antiviral drug–resistant CMV across the blood–brain barrier after T cell–depleted haploidentical peripheral blood stem cell transplantation.
Source: Diagnostic Microbiology and Infectious Disease - August 27, 2012 Category: Microbiology Authors: Tae-Dong Jeong, Heungsup Sung, Sang-Ho Choi, Sang-Oh Lee, Hye-Kyung Yoon, Mi-Na Kim, Ho Joon Im Tags: Case Reports Source Type: research

