Infectious Diseases
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 7.
Missed Opportunities for Early HIV Diagnosis in Correctional Facilities
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AIDS Patient Care and STDs , Vol. 0, No. 0.
Source: AIDS Patient Care and STDs - November 12, 2009 Category: Infectious Diseases Tags: article Source Type: journals
Reversal of Growth Failure in HIV-Infected Thai Children Treated with Non-Nucleoside Reverse Transcriptase Inhibitor–Based Antiretroviral Therapy
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AIDS Patient Care and STDs , Vol. 0, No. 0.
Source: AIDS Patient Care and STDs - November 12, 2009 Category: Infectious Diseases Tags: article Source Type: journals
Prevalence and Correlates of Elevated Body Mass Index among HIV-Positive and HIV-Negative Women in the Women's Interagency HIV Study
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AIDS Patient Care and STDs , Vol. 0, No. 0.
Source: AIDS Patient Care and STDs - November 12, 2009 Category: Infectious Diseases Tags: article Source Type: journals
Infectious Encephalitis in France in 2007: A National Prospective Study
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Conclusions. Our prospective study provides an overview of the clinical and etiologic patterns of acute infectious encephalitis in adults in France. Herpes simplex virus 1 remains the main cause of encephalitis, but bacteria accounts for the highest case‐fatality rates.
Source: Clinical Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals
Central Line–Associated Bloodstream Infections in Limited‐Resource Countries: A Review of the Literature
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Clinical Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles.
Central line–associated bloodstream infections (CLABSIs) are considered a significant cause of mortality in hospitalized patients; however, the incidence of CLABSIs in limited‐resource countries has not been explored analytically. Likewise, the appropriate interventions to prevent, control, and reduce CLABSIs have yet to be analyzed thoroughly. This review demonstrates that the CLABSI rate ranged from 1.6 to 44.6 cases per 1000 central line days in adult and pediatric intensive care units (ICUs) and from 2.6 to 60.0 cases per 1000 central...
Source: Clinical Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article HEALTHCARE EPIDEMIOLOGY Source Type: journals
Botswana: What's Driving HIV in Selebi-Phikwe?
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In most respects, there is nothing remarkable about Selebi-Phikwe, a mining town in northeastern Botswana with a population of about 50,000. The central business district is a sun-baked main street with a few shops and a taxi rank; the copper and nickel mine on its outskirts is the main source of employment.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
Age‐Related Increase in the Frequency of CD4+ T Cells That Produce Interferon‐γ in Response to Staphylococcal Enterotoxin B during Childhood
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Conclusions. These observations indicate that the IFN‐γ response of CD4+ T cells to SEB remains limited for a much longer interval than was reported elsewhere, extending to the second decade of life. Observed differences in CD45RO+CD4+ T cell function indicate that CD4+ T cells with the same phenotypes do not possess equivalent functional capabilities.
Source: The Journal of Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals
HIV‐1 Evolution Following Transmission to an HLA‐B*5801‐Positive Patient
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The Journal of Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles.
The human immunodeficiency virus type 1 (HIV‐1)–specific immune responses of patients with the HLA‐B*57/5801 alleles who spontaneously control viral replication serve as an important model for T cell–based HIV‐1 vaccines. Determining the breadth of this response and the extent of virologic escape in primary infection in these patients is therefore critical. Here we document the development of mutations in 3 HLA‐B*5801‐restricted epitopes in gag, nef, and pol in an HLA‐B*5801‐positive patient who had a viral load of onl...
Source: The Journal of Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article BRIEF REPORT Source Type: journals
Cost‐Effectiveness of Adult Circumcision in a Resource‐Rich Setting for HIV Prevention among Men Who Have Sex with Men
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Conclusions. Circumcision of adult MSM may be cost‐effective in this resource‐rich setting. However, the intervention costs are high relative to the costs spent on other HIV prevention programs.
Source: The Journal of Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals
A Live Attenuated H1N1 M1 Mutant Provides Broad Cross‐Protection against Influenza A Viruses, Including Highly Pathogenic A/Vietnam/1203/2004, in Mice
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The Journal of Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles.
The emergence of novel influenza A H1N1 and highly pathogenic avian influenza (HPAI) H5N1 viruses underscores the urgency of developing efficient vaccines against an imminent pandemic. M(NLS‐88R) (H1N1), an A/WSN/33 mutant with modifications in the multibasic motif 101RKLKR105 of the matrix (M1) protein and its adjacent region, was generated by reverse genetics. The M(NLS‐88R) mutant had in vitro growth characteristics similar to those of wild‐type A/WSN/33 (wt‐WSN), but it was attenuated in mice. Vaccination with M(NLS‐88R) n...
Source: The Journal of Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals
Efficacy of Inactivated Split‐Virus Influenza Vaccine against Culture‐Confirmed Influenza in Healthy Adults: A Prospective, Randomized, Placebo‐Controlled Trial
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Conclusion. TIV is efficacious against culture‐confirmed influenza in healthy adults. Trial Registration. ClinicalTrials.gov identifier: NCT00363870.
Source: The Journal of Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals
Borrelia burgdorferi Stimulates Macrophages to Secrete Higher Levels of Cytokines and Chemokines than Borrelia afzelii or Borrelia garinii
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The Journal of Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles.
To delineate the inflammatory potential of the 3 pathogenic species of Borrelia burgdorferi sensu lato, we stimulated monocyte‐derived macrophages from healthy human donors with 10 isolates each of B. burgdorferi, Borrelia afzelii, or Borrelia garinii recovered from erythema migrans skin lesions of patients with Lyme borreliosis from the United States or Slovenia. B. burgdorferi isolates from the United States induced macrophages to secrete significantly higher levels of interleukin (IL)‐8, CCL3, CCL4, IL‐6, IL‐10, and tumor nec...
Source: The Journal of Infectious Diseases Latest Issue - November 12, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals
Information for Pregnant Women Working in Education, Child Care, and Health Care Settings
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This revised document updates the information for employed women so that it is consistent with the most recent infection control guidance posted by CDC.
Source: CDC Swine Flu Updates - November 12, 2009 Category: Infectious Diseases Source Type: organizations
Africa: Lack of Political Will Threatens Aids Funding
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Universal access to antiretrovirals in poor countries is under threat as donors reduce funding for AIDS programmes, warns Medecins Sans Frontieres (MSF).
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
NEW: CDC Estimates of 2009 H1N1 Influenza Cases, Hospitalizations and Deaths in the United States, April - October 17, 2009
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CDC has developed a method to provide an estimated range of the total number of 2009 H1N1 cases, hospitalizations and deaths in the United States since April, 2009, as well as a breakdown of these estimates by age groups...
Source: CDC Swine Flu Updates - November 12, 2009 Category: Infectious Diseases Source Type: organizations
Societies Failing To Meet Healthcare Needs Of Women At Key Life Stages, WHO
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A new report by the World Health Organization released this week suggests that despite considerable progress in the past decades, societies are still failing to meet the healthcare needs of women at key stages in their lives, especially in adolescence and old age. WHO Director-General, Dr Margaret Chan told the press earlier this week that action was needed beyond the health sector to improve the health of girls and women worldwide.
Source: HIV / AIDS News From Medical News Today - November 12, 2009 Category: Infectious Diseases Tags: Women's Health / Gynecology Source Type: news
Flu Season Starts with Unprecedented Activity
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Since the end of August (MedPage Today) -- the official start of the 2009-2010 flu season -- influenza activity has increased rapidly across the U.S., nearly all of it attributable to the pandemic 2009 H1N1 influenza virus.
Source: MedPage Today Infectious Disease - November 12, 2009 Category: Infectious Diseases Source Type: news
Niger: Reinforcing Sex Education in High Schools
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High school students in the Niger capital, Niamey, learned to put HIV/AIDS and reproductive health in a broader context during a recent essay contest.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
Swine flu: drop in cases raises hopes for peak in second wave
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Drop in number of new cases for the first time in months raises hopes that the second wave of the pandemic has peaked.
Source: The Telegraph : Swine Flu A H1N1 - November 12, 2009 Category: Infectious Diseases Tags: swine flu peak Source Type: news
Africa: Disabled Should Claim Rights in UN Convention
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The United Nations Convention on the Rights of Persons with Disabilities (CRPD) should be used as a tool to improve access to HIV services for disabled people, who are often marginalized in national HIV policies, says a new report.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
New: 2009 H1N1 and People with Diabetes
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Influenza related information for people with diabetes
Source: CDC Swine Flu Updates - November 12, 2009 Category: Infectious Diseases Source Type: organizations
Long gestation of the swine flu vaccine
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Laboratory workers stare at an incubator full of eggs which will produce the next batch of H1N1 vaccine.
Source: The Telegraph : Swine Flu A H1N1 - November 12, 2009 Category: Infectious Diseases Tags: swine flu vaccine America Source Type: news
Ukraine Dead Increase to 213 - Still No Sequences
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The commentary discusses increases of fatal cases in Ukraine to 213. A map of the spreading outbreak is linked. (1/11/09 21:14)
Source: Recombinomics - November 12, 2009 Category: Infectious Diseases Source Type: info
The Newer Fluoroquinolones
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This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones—ciprofloxacin, levofloxacin, and moxifloxacin.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Maureen K. Bolon Source Type: journals
Current Use for Old Antibacterial Agents: Polymyxins, Rifamycins, and Aminoglycosides
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This article reviews three classes of antibacterial agents that are uncommonly used in bacterial infections and therefore can be thought of as special-use agents. The polymyxins are reserved for gram-negative bacilli that are resistant to virtually all other classes of drugs. Rifampin is used therapeutically, occasionally as a companion drug in treatment of refractory gram-positive coccal infections, especially those involving foreign bodies. Rifaximin is a new rifamycin that is a strict enteric antibiotic approved for treatment of traveler's diarrhea and is showing promise as a possible agent for refractory Clostridium di...
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Luke F. Chen, Donald Kaye Source Type: journals
Index
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Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Source Type: journals
Contents
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Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Source Type: journals
Forthcoming Issues
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Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Source Type: journals
Preface
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The discipline of infectious diseases is one of the most rapidly changing fields in medicine. In most specialties of medicine, diseases remain relatively stable, and diagnostic and therapeutic approaches change slowly. In infectious diseases, the syndromes change with the emergence of new organisms, development of resistant pathogens, and resurgence of infections that have virtually disappeared. Clearly, the diagnostic and therapeutic approaches must change rapidly. In no area of medicine does the knowledge and art of clinical practice change as rapidly as in the use of antimicrobial agents.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Keith S. Kaye, Donald Kaye Source Type: journals
Antibacterial Susceptibility Testing in the Clinical Laboratory
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This article familiarizes the clinician with the principles of bacterial susceptibility testing and reporting to facilitate communication with the clinical microbiology laboratory. As resistance continues to emerge among a wide range of clinically relevant bacteria, the complexity of this communication increases. This updated version provides an overview of the important susceptibility concerns for most commonly isolated bacterial pathogens.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Thomas L. Holland, Christopher W. Woods, Maria Joyce Source Type: journals
Pharmacokinetics and Pharmacodynamics of Antibacterial Agents
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This article reviews pharmacodynamics of antibacterial drugs, which can be used to optimize treatment strategies, prevent emergence of resistance and rationalize the determination of antimicrobial susceptibility. Important pharmacodynamic concepts include the requirements for bactericidal therapy for endocarditis and meningitis, for synergistic combinations to treat enterococcal endocarditis or to shorten the course of antimicrobial therapy, for obtaining maximal plasma concentration/minimal inhibitory concentration (MIC) ratios that are greater than 10 or 24 hour-area under the plasma concentration curve (AUC)/MIC ratios ...
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Matthew E. Levison, Julie H. Levison Source Type: journals
Pathogens Resistant to Antibacterial Agents
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This article reviews the epidemiology, molecular mechanisms of resistance, and treatment options for pathogens resistant to antimicrobial drugs.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Luke F. Chen, Teena Chopra, Keith S. Kaye Source Type: journals
Controlling Antimicrobial Resistance in the Hospital
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This article describes different infection control and antibiotic management strategies that can be used to control antimicrobial resistance in hospital settings.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Deverick J. Anderson, Keith S. Kaye Source Type: journals
Antibacterial Agents in Pediatrics
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This article describes the pharmacologic characteristics and therapeutic use of the most commonly prescribed antibacterials for pediatric patients. Newer agents currently under clinical investigation are discussed as well.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Susana Chavez-Bueno, Terrence L. Stull Source Type: journals
Antibacterial Agents in the Elderly
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Older patients disproportionately suffer the burden of infection in the community and in health care facilities. The rational approach to antimicrobial therapy for older patients with infection requires an appreciation and understanding of the complex immunologic, epidemiologic, pharmacologic, and microbiologic factors that influence the manifestations and consequences of infection in this group. Specific recommendations for common infectious syndromes must take into account the unique needs of older patients and should be tailored for each individual case.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Stephen Weber, Emily Mawdsley, Donald Kaye Source Type: journals
Use of Antibacterial Agents in Renal Failure
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This article provides background information on the pharmacokinetics of antibacterial agents in patients who have normal and impaired renal function. Tables are provided to allow quick determination of appropriate dosages for varying degrees of renal failure. The use of serum levels; newer strategies for cefazolin, vancomycin and aminoglycoside dosing; methods of dialysis and associated antibiotics dosage adjustments, and antibiotic toxicity in renal failure are reviewed.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Brett Gilbert, Paul Robbins, Lawrence L. Livornese Source Type: journals
Strategies and New Developments in the Management of Bacterial Meningitis
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The principles of antimicrobial therapy for acute bacterial meningitis include use of agents that penetrate well into cerebrospinal fluid and attain appropriate cerebrospinal fluid concentrations, are active in purulent cerebrospinal fluid, and are bactericidal against the infecting pathogen. Recommendations for treatment of bacterial meningitis have undergone significant evolution in recent years, given the emergence of pneumococcal strains that are resistant to penicillin. Clinical experience with use of newer agents is limited to case reports, but these agents may be necessary to consider in patients who are failing standard therapy.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Justine Miranda, Allan R. Tunkel Source Type: journals
Topical Antibacterial Agents
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This article reviews the literature on selected indications for these agents and provides in-depth examination of specific agents for the prophylaxis and treatment of skin and wound infections.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Peter A. Lio, Elaine T. Kaye Source Type: journals
Antibiotics for Gram-Positive Bacterial Infections: Vancomycin, Teicoplanin, Quinupristin/Dalfopristin, Oxazolidinones, Daptomycin, Dalbavancin, and Telavancin
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An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. The emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control this emergence of resistance are expected to be proposed. Newer antimicrobial agents that have activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Michael D. Nailor, Jack D. Sobel Source Type: journals
Newer Beta-lactam Antibiotics: Doripenem, Ceftobiprole, Ceftaroline, and Cefepime
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This article reviews the new beta-lactam (β-lactam) antibiotics doripenem, ceftobiprole, and ceftaroline. It covers pharmacokinetic and pharmacodynamic properties, dosing, in vitro activities, safety, and clinical trial results. Doripenem (Doribax) has been approved by the US Food and Drug Administration (FDA) for the treatment of complicated intra-abdominal and urinary tract infections. At this writing, ceftobiprole is under review by the FDA for approval based on results of phase 3 clinical trials, whereas at least one phase 3 clinical trial of ceftaroline has been completed. The article also reviews recent data suggest...
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Jose A. Bazan, Stanley I. Martin, Kenneth M. Kaye Source Type: journals
Macrolides, Ketolides, and Glycylcyclines: Azithromycin, Clarithromycin, Telithromycin, Tigecycline
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The advanced macrolides, azithromycin and clarithromycin, and the ketolide, telithromycin, are structural analogs of erythromycin. They have several distinct advantages when compared with erythromycin, including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once-daily administration, and improved tolerability. Clarithromycin and azithromycin are used extensively for the treatment of respiratory tract infections, sexually transmitted diseases, and Helicobacter pylori–associated peptic ulcer disease. Telithromycin is approved for the treatment of community-acquired pneumonia. Severe h...
Source: Infectious Diseases Clinics of North America - November 12, 2009 Category: Infectious Diseases Authors: Jerry M. Zuckerman, Fozia Qamar, Bartholomew R. Bono Source Type: journals
When Cooking, Teens Less Likely To Wash Hands, More Likely To Cross-Contaminate Raw Food Than Adults
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A Kansas State University study has shown that when preparing frozen foods, adolescents are less likely than adults to wash their hands and are more susceptible to cross-contaminating raw foods while cooking. "While half of the adults we observed washed their hands after touching raw chicken, none of the adolescents did," said Casey Jacob, a food safety research assistant at K-State.
Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today - November 12, 2009 Category: Infectious Diseases Tags: Nutrition / Diet Source Type: news
Africa: Mismatch Between HIV Spending and Need
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The global economic crisis may have the positive spinoff of forcing countries to allocate increasingly scare HIV/AIDS resources more efficiently.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
WHO Report Highlights Gender Disparities, Cites AIDS As Leading Cause Of Women's Deaths
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Women around the world are "denied a chance to develop their full human potential" because of a lack of essential health care throughout their lives, according to a World Health Organization report released Monday, Reuters reports.
Source: HIV / AIDS News From Medical News Today - November 12, 2009 Category: Infectious Diseases Tags: Women's Health / Gynecology Source Type: news
South Africa: Battle Won For HIV-Positive Soldiers
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The South African cabinet has approved a new policy prohibiting discrimination against soldiers and would-be recruits on the basis of their HIV status.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
South Africa: Military's HIV Ban Unlawful
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South Africa's High Court in Pretoria has ruled that the military's exclusion of HIV-positive people from recruitment, promotion and foreign deployment is unconstitutional.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
Theratechnologies Presents Combined Phase 3 Clinical Results At European AIDS Conference
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Theratechnologies (TSX:TH) announced that results from a pooled analysis from both its Phase 3 clinical trials evaluating tesamorelin for the treatment of excess abdominal fat in HIV-infected patients with lipodystrophy were presented as a poster (Poster number: #BPD2/1) at the 12th European AIDS Conference/EACS in Cologne, Germany. This Poster will also be presented as part of a "Best Poster" discussion on Friday.
Source: HIV / AIDS News From Medical News Today - November 12, 2009 Category: Infectious Diseases Tags: HIV / AIDS Source Type: news
Amarillo Biosciences Comments On New Findings Of H1N1 In Animals And Potential Effect On Human Infections
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Amarillo Biosciences, Inc. (ABI) (OTCBB: AMAR) reported that the American Veterinary Medical Association (AVMA) recently confirmed that a household cat in Iowa developed signs of respiratory infection caused by H1N1 influenza virus. The AVMA report adds cats to the growing list of animals, including ferrets, hogs (most recently in Indiana and Taiwan) and turkeys reported to be infected by H1N1 influenza virus.
Source: Infectious Diseases / Bacteria / Viruses News From Medical News Today - November 12, 2009 Category: Infectious Diseases Tags: Swine Flu Source Type: news
Nigeria: Healthcare For Women Still Below Expectation - UN Report
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A new United Nations (UN) report has revealed that many of the world's countries continue to fail to meet the health-care needs of women at key stages of their lives, such as adolescence or old age.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
Nigeria: Ummah Support Group
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We arrived early for the workshop and there were just a few of us in the room, most of them were staff of an NGO, the Society for Family Health SFH, which organised the event.
Source: AllAfrica News: HIV-Aids and STDs - November 12, 2009 Category: Infectious Diseases Source Type: news
