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Intensive Care

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Editorial Board
(Source: Journal of Critical Care)
Source: Journal of Critical Care - August 19, 2014 Category: Intensive Care Tags: Frontmatter Source Type: research

Table of Contents
(Source: Journal of Critical Care)
Source: Journal of Critical Care - August 19, 2014 Category: Intensive Care Tags: Frontmatter Source Type: research

Medical journals: A disruptive technology
From echocardiography to gram stains, from accelerometer-based agitation monitors to factors affecting sleep in the intensive care unit and to the second in a three part series on Brain Death, this issue of the Journal of Critical Care continues its efforts to provide relevant, timely, multidisciplinary, and sometimes ignored subjects for the practicing critical care professional. Journal readers may question whether the selection of articles for a particular issue is a matter of convenience and/or manuscript availability; the reality is somewhat different. (Source: Journal of Critical Care)
Source: Journal of Critical Care - August 19, 2014 Category: Intensive Care Authors: Philip D. Lumb Source Type: research

Impact of oral melatonin on critically ill adult patients with ICU sleep deprivation: study protocol for a randomized controlled trial
This study has a prospective, randomized, double-blind, controlled, parallel-group design. Eligible patients are randomly assigned to one of the two treatment study groups, labelled the 'melatonin group' or the 'placebo group'. A dose of 3 mg of oral melatonin or placebo is administered at 9:00 pm on four consecutive days. Earplugs and eye masks are made available to every participant. We plan to enrol 198 patients. The primary outcome is the objective sleep quality measured by the 24-hour polysomnography. The secondary outcomes are the subjective sleep quality assessed by the Richards Campbell Sleep Questionnaire, the anx...
Source: BioMed Central - August 18, 2014 Category: Journals (General) Authors: Huawei HuangLi JiangLing ShenGuobin ZhangBo ZhuJiajia ChengXiuming Xi Source Type: research

Is a good death possible in Australian critical and acute settings?: physician experiences with end-of-life care
Conclusions: Regardless of specialty, all physicians identified the problematic nature of providing expert palliation in critical and acute settings. Strategies for integrating specialised palliative and intensive care were offered with corresponding directions for future research and clinical development. (Source: BMC Palliative Care - Latest articles)
Source: BMC Palliative Care - Latest articles - August 18, 2014 Category: Palliative Care Authors: Steven Trankle Source Type: research

Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients
Conclusions Anaemia is common among non-cardiac and non-neurological surgical patients, and is associated with poor clinical outcome and increased healthcare resource use. Clinical trial registration NCT01203605 (ClinicalTrials.gov). (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - August 18, 2014 Category: Anesthesiology Authors: Baron, D. M., Hochrieser, H., Posch, M., Metnitz, B., Rhodes, A., Moreno, R. P., Pearse, R. M., Metnitz, P., for the European Surgical Outcomes Study (EuSOS) group for the Trials Groups of the European Society of Intensive Care Medicine and the European S Tags: Clinical Practice Source Type: research

Hypothermia improves oral and gastric mucosal oxygenation during hypoxic challenges
Conclusions Hypothermia attenuates the decrease in μHbO2 during additional hypoxic challenges independent of systemic or regional flow changes. A reduction in cardiac output during hypothermia is prevented by Ca2+ sensitization with levosimendan but not by K+ATP channel blockade with glibenclamide. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - August 18, 2014 Category: Anesthesiology Authors: Vollmer, C., Weiss, S., Beck, C., Bauer, I., Picker, O. Tags: Intensive Care Source Type: research

Benefits of continuous capnography monitoring for intensive care patients significantly outweigh any risks
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - August 18, 2014 Category: Anesthesiology Authors: Kelly, F. E., Georgiou, A. Tags: Correspondence Source Type: research

The (Correct) use of capnography will reduce airway complications in intensive care
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - August 18, 2014 Category: Anesthesiology Authors: McGrath, B. A. Tags: Correspondence Source Type: research

Family‐Centered Neonatal Intensive Care
(Source: Birth)
Source: Birth - August 18, 2014 Category: OBGYN Authors: Adik Levin, Beverley Chalmers Tags: Letter Source Type: research

Identifying Predictors of Hospital Readmission Following Congenital Heart Surgery through Analysis of a Multiinstitutional Administrative Database
ConclusionsReadmissions following congenital heart surgery are common and associated with significant resource consumption. While we describe independent predictors that may identify patients at risk for readmission prior to hospital discharge, there likely remains other unreported factors that may contribute to readmission following congenital heart surgery. (Source: Congenital Heart Disease)
Source: Congenital Heart Disease - August 17, 2014 Category: Cardiology Authors: Andrew H. Smith, Thomas P. Doyle, Bret A. Mettler, David P. Bichell, James C. Gay Tags: Original Article Source Type: research

Redirection in treatment goals: withdrawal of mechanical ventilation outside of the intensive care unit
‘Giving choice to families on a difficult journey’ Despite extensive technological advances and improved survival in paediatric intensive care unit (PICU) patients, many families are faced with a redirection in the aims of treatment to a journey of palliation. This transition in care from cure to palliation is difficult (and sometimes unimaginable) for the families involved, and it is also challenging for professionals, technically and emotionally. There are no ‘second chances’ in end-of-life care. The experience and memories of that journey will remain with the relatives forever. There is increasin...
Source: Archives of Disease in Childhood - August 17, 2014 Category: Pediatrics Authors: Mayer, A.-P. T. Tags: Editorial Source Type: research

Withdrawal of ventilatory support outside the intensive care unit: guidance for practice
Conclusions Planned withdrawal of ventilatory support outside the intensive care setting is challenging and resource intensive. The development of local collaborations and guidance can enable parents of children dependent on intensive care to consider a preferred place of death for their child, which may be outside the intensive care unit. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - August 17, 2014 Category: Pediatrics Authors: Laddie, J., Craig, F., Brierley, J., Kelly, P., Bluebond-Langner, M. Tags: Open access, Child health, Hospice, Adult intensive care Original article Source Type: research

Am J Respir Crit Care Med; +91 new citations
91 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Respir Crit Care Med These pubmed results were generated on 2014/08/16PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources. (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - August 16, 2014 Category: Intensive Care Tags: Report Source Type: research

Through a glass darkly...... observations from the other side
Most of the projects in which Medical Physics and Bioengineering (MPBE) staff participate are generated by our clinical and/or nursing colleagues. These projects arise typically to solve a clinical or research problem as perceived by hospital staff. Very few projects however are generated through direct contact with patients. During the course of last summer the author was diagnosed with an illness which necessitated a lengthy operation, hospital stay including 10 days in Intensive Care and extended recovery at home. (Source: Physica Medica: European Journal of Medical Physics)
Source: Physica Medica: European Journal of Medical Physics - August 16, 2014 Category: Journals (General) Authors: Wilhelm van der Putten Tags: IAPM 5th Annual Scientific Meeting 2014 Source Type: research

In search of the “Holy Grail”: Will we ever prove the efficacy of Rapid Response Systems (RRS)?
It is hard to think of an intervention in the last two decades that has been implemented in such a widespread fashion, and so effectively, but with so little evidence as Rapid Response Systems.1 No one from an administrative, clinical or research perspective can question the underlying assumptions that underpin RRS utilization. A plethora of research articles in the 1990s and 2000s have described the risk factors for unexpected patient clinical deterioration, that eventually results in either in-hospital cardiac arrest (IHCA), unplanned Intensive Care Unit (ICU) admission from the general ward or unexpected hospital mortal...
Source: Resuscitation - August 16, 2014 Category: Emergency Medicine Authors: Michael Buist, Adam Mahoney Tags: Editorials Source Type: research

Citrate anticoagulation versus systemic heparinisation in continuous venovenous hemofiltration in critically ill patients with acute kidney injury: a multi-center randomized clinical trial
IntroductionBecause of ongoing controversy, renal and vital outcomes are compared between systemically administered unfractionated heparin and regional anticoagulation with citrate-buffered replacement solution in predilution mode, during continuous venovenous hemofiltration (CVVH) in critically ill patients with acute kidney injury (AKI). Methods: In this multi-center randomized controlled trial, patients admitted to the intensive care unit requiring CVVH and meeting inclusion criteria, were randomly assigned to citrate or heparin. Primary endpoints were mortality and renal outcome in intention-to-treat analysis. Secondar...
Source: Critical Care - August 16, 2014 Category: Intensive Care Authors: Louise SchilderS NurmohamedFrank BoschIlse PurmerSylvia den BoerCynthia KleppeMarc VervloetAlbertus BeishuizenArmand GirbesPieter ter WeeAB Groeneveld Source Type: research

Compression force on the upper jaw during neonatal intubation: Mannequin study
ConclusionThe upper jaw is exposed to a significant compression force during intubation. Although such exposure is brief, it has the potential to cause tissue injury. Contact of the laryngoscope blade with the upper jaw occurred in all intubation attempts with the currently used design of laryngoscope. (Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - August 15, 2014 Category: Pediatrics Authors: Srinivasa Murthy Doreswamy, Khaled Almannaei, Chris Fusch, Sandesh Shivananda Tags: Original Article Source Type: research

Recombinant activated factor VIIa to treat refractory lower gastrointestinal hemorrhage in a patient with recently implanted mechanical valve: a case report
Conclusions: A favorable outcome was achieved after administration of recombinant activated factor VII, which controlled the patient's severe lower gastrointestinal bleeding. This outcome suggests the need to raise awareness about the use of this drug in dire circumstances when other conventional measures fail or are unsuitable. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - August 15, 2014 Category: Epidemiology Authors: Amr S OmarSuraj SudarsananHesham EwilaAli Kindawi Source Type: research

A specialized post anaesthetic care unit improves fast-track management in cardiac surgery: a prospective randomized trial
IntroductionFast-track treatment in cardiac surgery has become the global standard of care. We compared the efficacy and safety of a specialised post-anaesthetic care unit (PACU) to a conventional intensive care unit (ICU) in achieving defined fast-track end-points in adult patients after elective cardiac surgery. Methods: In a prospective, single blinded, randomized study, 200 adult patients undergoing elective cardiac surgery (coronary artery bypass graft (CABG), valve surgery or combined CABG and valve surgery), were selected to receive their postoperative treatment either in the ICU (n?=?100), or in the PACU (n?=?100)....
Source: Critical Care - August 15, 2014 Category: Intensive Care Authors: Stefan ProbstChristof CechDirk HaentschelMarkus ScholzJoerg Ender Source Type: research

Impact of platelet transfusion on toxicity and mortality after hematopoietic progenitor cell transplantation.
CONCLUSION: HPCT-related toxicity and mortality are associated with increased PLT transfusion events. Alternative strategies to reduce PLT transfusions after HPCT may warrant future study. PMID: 25125085 [PubMed - as supplied by publisher] (Source: Transfusion)
Source: Transfusion - August 15, 2014 Category: Hematology Authors: Christou G, Kekre N, Petrcich W, Tokessy M, Neurath D, Giulivi A, Saidenberg E, McDiarmid S, Atkins H, Bence-Bruckler I, Bredeson C, Huebsch L, Sabloff M, Sheppard D, Tay J, Tinmouth A, Allan DS Tags: Transfusion Source Type: research

Magnesium sulphate for preventing preterm birth in threatened preterm labour.
CONCLUSIONS: Magnesium sulphate is ineffective at delaying birth or preventing preterm birth, has no apparent advantages for a range of neonatal and maternal outcomes as a tocolytic agent and its use for this indication may be associated with an increased risk of total fetal, neonatal or infant mortality (in contrast to its use in appropriate groups of women for maternal, fetal, neonatal and infant neuroprotection where beneficial effects have been demonstrated). PMID: 25126773 [PubMed - as supplied by publisher] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 15, 2014 Category: Journals (General) Authors: Crowther CA, Brown J, McKinlay CJ, Middleton P Tags: Cochrane Database Syst Rev Source Type: research

Neonatal seizures: dilemmas in treatment
Neonatal seizures (NS) are a common manifestation of neurological dysfunction in the newborn infant. Neonates having seizures in the neonatal period are at risk of mortality and though mortality due to NS has decreased over the years from 40% to about 20%, the prevalence of long-term neurodevelopment sequelae has largely remained unchanged at around 30%. The management of neonatal seizures lacks a strong evidence base, and reduced mortality may be linked to improvement in supportive intensive care (e.g. (Source: Paediatrics and Child Health)
Source: Paediatrics and Child Health - August 14, 2014 Category: Pediatrics Authors: Alok Sharma Tags: Personal Practice Source Type: research

Isolated dissection of the superior mesenteric artery treated using open emergency surgery
Conclusion: Open surgical repair remains important in cases of anatomic variants of visceral arteries and suspected bowel infarction. Therefore, it is important that knowledge about open surgical techniques still be taught and trained. (Source: World Journal of Emergency Surgery)
Source: World Journal of Emergency Surgery - August 14, 2014 Category: Emergency Medicine Authors: Markus WagenhäuserTolga SagbanMareike WitteMansur DuranHubert SchelzigAlexander Oberhuber Source Type: research

Level of adherence to the GOLD strategy document for management of patients admitted to hospital with an acute exacerbation of COPD
ConclusionsHealth professionals in the respiratory team had better adherence to GOLD as compared to health professionals in other teams. Nonetheless, pharmacological interventions were both appropriately prescribed and also over‐prescribed, whereas non‐pharmacological interventions were used rarely, suggesting a need for practice review in these areas. (Source: Respirology)
Source: Respirology - August 14, 2014 Category: Respiratory Medicine Authors: Clarice Y. Tang, Nicholas F. Taylor, Christine F. McDonald, Felicity C. Blackstock Tags: Original Article Source Type: research

Altered immune status of circulating T lymphocytes during sepsis: children also
Altered immune status of blood leukocytes is a general phenomenon observed in adult patients with sepsis or septic shock. This is also the case in children with septic shock for both T helper 1 and T helper 2 lymphocytes, as demonstrated by their reduced ex vivo cytokine production upon activation by phytohemagglutinin. (Source: Critical Care)
Source: Critical Care - August 14, 2014 Category: Intensive Care Authors: Jean-Marc Cavaillon Source Type: research

A comparison of mid-forehead and axillary temperatures in newborn intensive care
; B J Taylor (Source: Journal of Perinatology)
Source: Journal of Perinatology - August 14, 2014 Category: Perinatology & Neonatology Authors: J Robertson-SmithF T McCaffreyR SayersS WilliamsB J Taylor Source Type: research

Comparative evaluation of high-flow nasal cannula and conventional oxygen therapy in paediatric cardiac surgical patients: a randomized controlled trial
CONCLUSIONS HFNC had no impact on PaCO2 values. The use of HFNC appeared to be safe and improved PaO2 in paediatric cardiac surgical patients. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - August 14, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Testa, G., Iodice, F., Ricci, Z., Vitale, V., De Razza, F., Haiberger, R., Iacoella, C., Conti, G., Cogo, P. Tags: Anesthesia, Great vessels, Mechanical Circulatory Assistance Congenital Source Type: research

Adjunct coronary endarterectomy increases myocardial infarction and early mortality after coronary artery bypass grafting: a meta-analysis
Coronary endarterectomy (CE) may provide a useful adjunct to coronary artery bypass grafting (CABG) in patients with extensive, diffuse coronary atheroma. However, concerns regarding its morbidity and mortality have created uncertainty as to the role of CE in the current era. The aim of this study was therefore to quantitatively summarize the short- and long-term outcomes of CE. Twenty observational studies were identified by systematic literature search, incorporating 54 440 patients (7366 CABG + CE; 47 074 CABG only), which were analysed using random-effects modelling. Heterogeneity, subgroup analysis, quality scoring an...
Source: Interactive CardioVascular and Thoracic Surgery - August 14, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Soylu, E., Harling, L., Ashrafian, H., Casula, R., Kokotsakis, J., Athanasiou, T. Tags: Coronary disease, Myocardial infarction Adult Cardiac Source Type: research

In surgeons performing cardiothoracic surgery is sleep deprivation significant in its impact on morbidity or mortality?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: is there a difference in cardiothoracic surgery outcomes in terms of morbidity or mortality of patients operated on by a sleep-deprived surgeon compared with those operated by a non-sleep-deprived surgeon? Reported search criteria yielded 77 papers, of which 15 were deemed to represent the best evidence on the topic. Three studies directly related to cardiothoracic surgery and 12 studies related to non-cardiothoracic surgery. Recommendations are based on 18 121 cardiothoracic patients and 214 666 non-cardiot...
Source: Interactive CardioVascular and Thoracic Surgery - August 14, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Asfour, L., Asfour, V., McCormack, D., Attia, R. Tags: Pleura, Education, Electrophysiology - arrhythmias, Professional affairs Adult Cardiac Source Type: research

Successful operative rib fixation of traumatic flail chest in a patient with osteogenesis imperfecta
Increasing attention has been directed towards operative rib fixation of traumatic flail chest; reported benefits include more rapid weaning from the ventilator, decreased intensive care unit stays, decreased complications and improved functional results. The outcomes of this surgical intervention in patients with osteogenesis imperfecta, a rare condition characterized by low bone density and bone fragility, are unknown. This case demonstrates that, in the management of traumatic flail chest in a patient with osteogenesis imperfecta, surgical fixation can be successful and should be considered early. (Source: Interactive C...
Source: Interactive CardioVascular and Thoracic Surgery - August 14, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kulaylat, A. N., Chesnut, C. H., Santos, A. P., Armen, S. B. Tags: Chest wall Thoracic Source Type: research

Emergency medical services versus private transport of trauma patients in the Sultanate of Oman: a retrospective audit at the Sultan Qaboos University Hospital
Conclusions EMS transported trauma patients had a statistically non-significant 36% reduction in mortality compared with privately transported patients admitted to the Sultan Qaboos University Hospital in 2011. Further, research that incorporates prehospital factors such as crash to arrival of EMS services and transport time to definitive healthcare facility should be conducted to evaluate the effectiveness of such a system in trauma care. Since non-EMS transport is likely to continue, public first aid training is critical to reduce mortality and morbidity of road traffic trauma in Oman. (Source: Emergency Medicine Journal)
Source: Emergency Medicine Journal - August 14, 2014 Category: Emergency Medicine Authors: Al-Shaqsi, S., Al-Kashmiri, A., Al-Hajri, H., Al-Harthy, A. Tags: Trauma CNS / PNS, Trauma Prehospital care Source Type: research

One year mortality associated with the simplified missed score
Conclusion In patients admitted with an infection, increasing simplified MISSED scores in the ED were associated with significantly increased mortality rates at one year. Kaplan Meier plot illustrating the one-year survival associated with the simplified MISSED score (Source: Emergency Medicine Journal)
Source: Emergency Medicine Journal - August 14, 2014 Category: Emergency Medicine Authors: Sivayoham, N., Holmes, P., Mitchinson, S., Cecconi, M., Rhodes, A. Tags: DAY THREE: FREE PAPERS: SEMINAR ROOMS 1[amp ]2, 10:00-11:30 Source Type: research

Tracing the emergence of multidrug-resistant Acinetobacter baumannii in a Taiwanese hospital by evaluating the presence of integron gene intI1
Conclusions: Although the presence of the intI1 gene does not seem suitable for tracing MDRAB emergence in Changhua County, two predominant clones were identified by PFGE, and subsequent studies to identify whether these clones were responsible for original nosocomial infection are needed. (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - August 14, 2014 Category: Research Authors: Chang-Hua ChenChieh-Chen Huang Source Type: research

Comparing mortality among adult, general intensive care units in England with varying intensivist cover patterns: a retrospective cohort study
There is no relationship between days of continuous cover by a single intensivist and patient outcomes in adult, general ICUs in England but intensivist participation in handover is associated with increased mortality. (Source: Critical Care)
Source: Critical Care - August 14, 2014 Category: Intensive Care Authors: M WilcoxDavid HarrisonAlasdair ShortMax JonasKathryn Rowan Source Type: research

Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock
Conclusions: In our hypodynamic model of endotoxic shock, infusion of hypertonic sodium lactate improves hemodynamic and microvascular reactivity with a negative fluid balance and a better oxygenation. (Source: Critical Care)
Source: Critical Care - August 14, 2014 Category: Intensive Care Authors: Thibault DuburcqRaphaël FavoryDaniel MathieuThomas HubertJacques MangalaboyiValery GmyrLaurence QuintanePatrice MaboudouFrançois PattouMercé Jourdain Source Type: research

A comparison of parent and staff perceptions of setting-specific and everyday stressors encountered by parents with very preterm infants experiencing neonatal intensive care
Stress responses among parents of premature infants experiencing the neonatal intensive care unit (NICU) environment are widely reported. However, less is known about how nurses perceive parents' experiences or how stressors relating to demands on family finances and practical challenges associated with infant hospitalization contribute to parental stress levels in the NICU. (Source: Early Human Development)
Source: Early Human Development - August 13, 2014 Category: Perinatology & Neonatology Authors: Verena E. Pritchard, Argène Montgomery-Hönger Source Type: research

Point‐of‐care blood glucose measurement errors overestimate hypoglycaemia rates in critically ill patients
ConclusionsDocumentation of point‐of‐care blood glucose measurement errors likely overestimates ICU hypoglycaemia rates and can be reduced by a quality improvement effort. The currently used hypoglycaemic patient‐day metric does not evaluate recurrent or prolonged events that may be more likely to cause patient harm. The monitored patient‐day as currently defined may not be the optimal denominator to determine inpatient hypoglycaemic risk. Copyright © 2014 John Wiley & Sons, Ltd. (Source: Diabetes/Metabolism Research and Reviews)
Source: Diabetes/Metabolism Research and Reviews - August 13, 2014 Category: Endocrinology Authors: Jean‐Jacques Nya‐Ngatchou, Dawn Corl, Susan Onstad, Tom Yin, Tracy Tylee, Louise Suhr, Rachel E. Thompson, Brent E. Wisse Tags: Research Article Source Type: research

The benefit of specialized team approaches in patients with acute kidney injury undergoing continuous renal replacement therapy: propensity score matched analysis
Conclusions: A well-organized CRRT team could be beneficial for clinical outcomes through improving quality of care in AKI patients requiring CRRT treatment in the ICU. (Source: Critical Care)
Source: Critical Care - August 13, 2014 Category: Intensive Care Authors: Hyung OhMi LeeChan KimDae KimHye LeeJung ParkSungwon NaSeung HanShin-Wook KangShin KohTae-Hyun Yoo Source Type: research

Development and validation of a UHPLC diode array detector method for meropenem quantification in human plasma.
CONCLUSIONS: . The method meets the requirements to be applied for meropenem concentration measurements in pharmacokinetics studies and clinical routine. The results suggest the need for therapeutic drug monitoring of meropenem in treated critically-ill patients. PMID: 25128839 [PubMed - as supplied by publisher] (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - August 13, 2014 Category: Biochemistry Authors: Casals G, Hernández C, Hidalgo S, Morales B, López-Púa Y, Castro P, Fortuna V, Martínez JA, Brunet M Tags: Clin Biochem Source Type: research

Clinical outcome and blood transfusion after infant cardiac surgery with a routine use of conventional ultrafiltration.
CONCLUSIONS: Routine use of conventional ultrafiltration during the cardiac surgery for patients with a bodyweight less than 10 kg was a safe technique that allowed us to achieve higher hematocrit levels at the end of the operation without additional transfusions of allogenic blood. On the other hand, ultrafiltration did not improve the clinical end points. PMID: 25122118 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - August 13, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Golab H, Kissler J, de Jong P, van de Woestijne P, Takkenberg J, Bogers A Tags: Perfusion Source Type: research

Comment on: Transfusion practices in a neonatal intensive care unit in a Brazilian town
(Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - August 12, 2014 Category: Hematology Source Type: research

Transfusion practices in a neonatal intensive care unit in a city in Brazil
CONCLUSION: This study shows that the characteristics and the transfusion practices for newborns admitted in the neonatal intensive care units of Juiz de Fora are similar to recent pubications. There was no significant reduction in the number of transfusions per child in the restrictive group compared to the liberal group. Restrictive transfusions are an independent risk factor for peri-intraventricular hemorrhages and death. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - August 12, 2014 Category: Hematology Source Type: research

Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study
Conclusions: HAdV-55 may cause severe ARDS in immunocompetent young men. Persistent high fever, dyspnea, and rapid progression to respiratory failure within 2?weeks, together with bilateral consolidations and infiltrates, are the most frequent clinical manifestations of HAdV-55-induced severe ARDS. Viral load monitoring may help predict patients? severity and outcome. NPPV and IMV failure rate were very high, and ECMO may be the choice of respiratory support.Trial registrationClinicaltrials.gov NCT01585922. Registered 20 April 2012. (Source: Critical Care)
Source: Critical Care - August 12, 2014 Category: Intensive Care Authors: Bing SunHangyong HeZheng WangJiuxin QuXuyan LiChengjun BanJun WanBin CaoZhaohui TongChen Wang Source Type: research

Relapsing Guillain-Barre syndrome in pregnancy and postpartum
We report a unique case of GBS complicating pregnancy in the third trimester followed by a relapse in the postpartum period. She made a good recovery with supportive measures and a repeat course of IVIG during the relapse. (Source: Annals of Indian Academy of Neurology)
Source: Annals of Indian Academy of Neurology - August 12, 2014 Category: Neurology Authors: S Meenakshi-SundaramK SwaminathanSN KarthikS Bharathi Source Type: research