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This page shows you the most recent publications within this specialty of the MedWorm directory.

Clinical Management of Pregnancy in Women with Goodpasture Syndrome
Conclusion: The occurrence of GS during pregnancy is very rare. This unusual pregnancy complication is associated with significant maternal and fetal morbidity. The management of GS during pregnancy requires intensive care and multidisciplinary cooperation.Gynecol Obstet Invest (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 27, 2015 Category: OBGYN Source Type: research

Gastric tonometry guided therapy in critical care patients: a systematic review and meta-analysis
Conclusions: In critical care patients, gastric tonometry guided therapy can reduce total mortality. Patients with normal pHi on admission partially drive the ultimate result of this outcome; it may indicate that these patients may be more sensitive to this therapy. (Source: Critical Care)
Source: Critical Care - January 27, 2015 Category: Intensive Care Authors: Xin ZhangWei XuanPing YinLinlin WangXiaodan WuQingping Wu Source Type: research

Fatal hyperammonemia and carbamoyl phosphate synthetase 1 (CPS1) deficiency following high-dose chemotherapy and autologous hematopoietic stem cell transplantation
This study adds to the understanding of chemotherapy-induced hyperammonemia as drug-induced CPS1 deficiency is suggested. Moreover, we highlight the need for urgent diagnostic and therapeutic strategies addressing a possible secondary urea cycle failure in future patients with hyperammonemia during chemotherapy and stem cell transplantation. (Source: Molecular Genetics and Metabolism)
Source: Molecular Genetics and Metabolism - January 27, 2015 Category: Genetics & Stem Cells Source Type: research

Multi-pathogen real-time PCR system adds benefit for my patients: yes
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

Severe infections as the leading complication after the Lushan earthquake
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

Multipathogen real-time PCR system adds benefit for my patients: no
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

Comparison of different equations to assess glomerular filtration in critically ill patients
Conclusions In this cohort of patients, estimates of GFR had low accuracy and precision. Cystatin C based formulas, especially CKD-EPIcr-cys, showed limited bias; however, the accuracy and precision of these estimates were still insufficient. Measured urinary creatinine clearance overestimates GFR, but may provide a cheap alternative, when this is taken into account. (Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

How to wean a patient from veno-arterial extracorporeal membrane oxygenation
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

Predicting the determinants of volume responsiveness
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

Improving donor management and transplantation success: more research is needed
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

What’s new in post-ICU cognitive impairment?
(Source: Intensive Care Medicine)
Source: Intensive Care Medicine - January 27, 2015 Category: Intensive Care Source Type: research

Development of END-of-Life ScorING-System to identify critically ill patients after initial critical care who are highly likely to die: a pilot study.
CONCLUSIONS: In these preliminary results, ENDING-s shows acceptable calibration and discrimination properties. ENDING--S may raise awareness among ICU physicians about the importance of integrating palliative care into ICU daily practice. PMID: 25616205 [PubMed - as supplied by publisher] (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - January 26, 2015 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research

Low-dose hydrocortisone reduces norepinephrine duration in severe burn patients: a randomized clinical trial
Conclusions: In this placebo-controlled, randomized, double-blind clinical trial, we show for the first time that the administration of low-dose hydrocortisone in burn patients with severe shock reduces vasopressor administration.Trial registrationClinicaltrial.gov NCT00149123. Registered 6th September 2005. (Source: Critical Care)
Source: Critical Care - January 26, 2015 Category: Intensive Care Authors: Fabienne VenetJonathan PlassaisJulien TextorisMarie-Angélique CazalisAlexandre PachotMarc Bertin-MaghitChristophe MagninThomas RimmeléGuillaume MonneretSylvie Tissot Source Type: research

Association of time in blood glucose range with outcomes following cardiac surgery
Background: The importance of optimal postoperative glycemic control in cardiac patients remains unclear. Various glycemic targets have been prescribed to reduce wound infection and overall mortality rates.Aim of the work: To assess glucose control, as determined by time in range (TIR), in patients with glycemic targets of 6.0 to 8.1 mmol/L, and to determine factors related to poor control. Methods: This prospective descriptive study evaluated 227 consecutive patients, 100 with and 127 without diabetes, after cardiac surgery. Patients received insulin to target glucose concentrations of 6.0 to 8.1 mmol/L. Data analyzed inc...
Source: Epidemiologic Perspectives and Innovations - January 26, 2015 Category: Epidemiology Authors: Amr S OmarAhmed SalamaMahmoud AllamYasser ElgoharyShaban MohammedAlejandro Kohn TuliRajvir Singh Source Type: research

Keeping Up With Outcomes for Infants Born at Extremely Low Gestational Ages
Neonatal intensive care has been one of the success stories of the past 30 years, with steadily improving survival and slowly improving long-term outcomes for infants born early. In the 1980s, few infants born at 25 through 26 weeks of gestation survived, but now high survival and low morbidity rates are expected throughout the developed world. The outcome for infants born at the decreasing limit of viability has continually evoked anxiety in terms of the balance between poor survival with high rates of neuroimpairment and the burden of providing intensive care for many weeks or months. In 1980, this limit was 25 through 2...
Source: JAMA Pediatrics - January 26, 2015 Category: Pediatrics Source Type: research

Efficacy of noninvasive ventilation after planned extubation: A systematic review and meta-analysis of randomized controlled trials
The objective our meta-analysis is to update the evidence on the efficacy of noninvasive ventilation (NIV) compared with conventional oxygen therapy after planned extubation. We did a systematic literature review of database, including Pubmed, EMBASE, and Cochrane. We included randomized controlled trials comparing NIV with conventional oxygen therapy after planned extubation in medical intensive care unit (ICU) in our analysis. The results of our meta-analysis is consistent with the results of previous reviews and show that NIV decreased reintubation rate significantly as compared to conventional oxygen therapy in chronic...
Source: Heart and Lung: The Journal of Acute and Critical Care - January 26, 2015 Category: Respiratory Medicine Source Type: research

Insomnia is associated with quality of life impairment in medical-surgical intensive care unit survivors
Conclusions Insomnia is common among ICU survivors. Post-ICU insomnia is significantly associated with mental HRQOL and could identify ICU survivors who may benefit from further psychiatric evaluation. (Source: Heart and Lung: The Journal of Acute and Critical Care)
Source: Heart and Lung: The Journal of Acute and Critical Care - January 26, 2015 Category: Respiratory Medicine Source Type: research

A 5-year retrospective evaluation of snakebite cases in Hatay, Turkey
This study aims to evaluate snakebite cases in terms of medical follow-up, antivenom therapy and antivenom reactions. Medical records of patients admitted to emergency department between January 1, 2006 and December 31, 2010 were retrospectively investigated. Snakebite-related cases of a total of 125 patients were included in the scope of the study. Of the total 125 cases, 54.4% were male and 45.6% were female. Most of cases (n: 65, 52%) were aged over 30 years, while the mean age was 34.87 ± 19.29 years. Snakebite-related applications to the emergency department were mostly seen in June with 27 ...
Source: Toxicology and Industrial Health current issue - January 26, 2015 Category: Toxicology Authors: Karakus, A., Zeren, C., Celik, M. M., Arica, S., Ozden, R., Duru, M., Tasın, V. Tags: Articles Source Type: research

The Ketogenic Diet as Broad-Spectrum Treatment for Super-Refractory Pediatric Status Epilepticus: Challenges in Implementation in the Pediatric and Neonatal Intensive Care Units
We describe our recent experience with instituting the ketogenic diet for 4 critically ill children in refractory status epilepticus, ranging in age from 9 weeks to 13.5 years after failure of traditional treatment. The ketogenic diet allowed these patients to be weaned off continuous infusions of anesthetics without recurrence of status epilepticus, though delayed ketosis and persistently elevated glucose measurements posed special challenges to effective initiation, and none experienced complete seizure cessation. The ease of sustaining myocardial function with fatty acid energy substrates compares favorably over the myo...
Source: Journal of Child Neurology - January 26, 2015 Category: Neurology Authors: Cobo, N. H., Sankar, R., Murata, K. K., Sewak, S. L., Kezele, M. A., Matsumoto, J. H. Tags: Brief Communication Source Type: research

A Survey of Moral Distress Across Nurses in Intensive Care Units (FR416-A)
In 2008 the American Association of Critical Care Nurses (AACN) published a position statement on moral distress that included a call to action for nurses to recognize and name the experience of moral distress and as commit to using professional and institutional resources to address it. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Brianna Morgan, Elise Tarbi Source Type: research

Effects of a Nurse-Led Primary Palliative Care Bundle on Specialist Palliative Care Consults in the ICU (FR416-C)
Specialist palliative care consults (SPCCs) in intensive care units (ICUs) reduce lengths of stay and nonbeneficial intensive care treatments, improve family satisfaction, and better manage symptoms of seriously ill patients. However, palliative care specialists are in scarce supply and not available in all hospitals. It is essential that primary palliative care (PPC) be incorporated as a core ICU service. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Carolyn Clevenger, Danielle Moulia, Kenneth Hepburn, Tammie Quest Source Type: research

Decision-Making Consensus in the NICU: What Does Parent-Clinician Collaboration Actually Look Like? (FR416-B)
We know little about how parents and clinicians collaborate to make decisions for critically ill infants in the neonatal intensive care unit (NICU). Existing data are retrospective or hypothetical, emphasizing clinicians’ over parents’ perspectives. These studies suggest parents and neonatologists leave conversations with different perceptions about which decisions were discussed. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Renee Boss, Gail Geller, Pamela Donohue, Robert Arnold Source Type: research

The Mock No-Code: Cases and Resources for Professionals in Pediatric ICU's (FR469-A)
In the last decade most children’s hospital deaths occur in intensive care units following orders to limit resuscitative efforts. Although physicians and nurses in pediatric ICUs are usually required to be certified in pediatric advanced life support, these professionals are less likely to participate in a “code blue” event than they are to be involved in caring for a child whose death is anticipated or will follow a planned withdrawal of care. Training for these expected pediatric ICU deaths is not required and rarely standardized in most children’s hospitals. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Kenneth Pituch, Maureen Giacomazza, Matthew Niedner Tags: Interactive Educational Exchange Source Type: research

Integrating an Advance Care Planning Clinical and Education Intervention to Improve Patient-Centered Care and End of Life Care Planning among Chronically Ill Older Adults (SA545-C)
Early identification of advance care planning (ACP) preferences among older adults (OA) with advanced illness is critical to avoid the approximately 40% of all deaths which occur in acute care settings and 50% within intensive care units. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Linda May, Sandra Sanchez-Reilly, Shuko Lee, Eneida-Yvette Gonzalez, Jeanette Ross Source Type: research

Characterizing Parent-Clinician Discussions About Critically Ill Infants: Empirical Observation of Real-Time Conversations (S713)
Clinicians in the neonatal intensive care unit (NICU) must engage in clear and compassionate communication with families. Developing best practices for counseling, and for training clinicians in key communication skills, are hampered without empirical, observational data about how these conversations unfold. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Renee Boss, Susan Larson, Debra Roter, Pamela Donohue Source Type: research

The Activities of Chaplains in the Intensive Care Unit (S718)
Patients and families commonly experience significant spiritual stress during an intensive care unit (ICU) admission. While a majority of patients report that they want spiritual support, little is known about how these issues are addressed by hospital chaplains. Our goal was to describe the epidemiology, timing, and type of hospital chaplain consultation in adult ICUs, as well as the patient population they serve. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - January 25, 2015 Category: Palliative Care Authors: Philip Choi, Farr Curlin, Christopher Cox Source Type: research

Safe patient monitoring is challenging but still feasible in a neonatal intensive care unit with single family rooms
ConclusionSafe patient monitoring was challenging in a NICU with single family rooms, but possible by employing a distributed alarm system. The low number of repeat alarms indicated quick response times.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 25, 2015 Category: Pediatrics Authors: C. Pul, H. v.d. Mortel, J. v.d. Bogaart, T. Mohns, P. Andriessen Tags: Regular Article Source Type: research

Lung Ultrasound in the Intensive Care Unit
The use of ultrasound (US) for vascular access in the intensive care unit (ICU) is commonplace and, in fact, has become the standard of practice when inserting internal jugular venous catheters.1,2 Physicians in many countries outside the United States have expanded the role of US to include several different diagnostic modalities for multiple organ systems. Algorithms for rapid diagnosis during acute clinical decompensation have been developed based on a growing body of literature supporting the benefits of using US in this role. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - January 24, 2015 Category: Anesthesiology Authors: Sean Kiley, Christopher Cassara, Brenda G. Fahy Tags: Review Article Source Type: research

Management of Critical Asthma Syndrome During Pregnancy
Abstract One-third of pregnant asthmatics experience a worsening of their asthma that may progress to a critical asthma syndrome (CAS) that includes status asthmaticus (SA) and near-fatal asthma (NFA). Patients with severe asthma before pregnancy may experience more exacerbations, especially during late pregnancy. Prevention of the CAS includes excellent asthma control involving targeted early and regular medical care of the pregnant asthmatic, together with medication compliance. Spontaneous abortion risk is higher in pregnant women with uncontrolled asthma than in non-asthmatics. Should CAS occur during pregnan...
Source: Clinical Reviews in Allergy and Immunology - January 24, 2015 Category: Allergy & Immunology Source Type: research

Critical Asthma Syndrome in the ICU
Abstract Critical asthma syndrome represents the most severe subset of asthma exacerbations, and the critical asthma syndrome is an umbrella term for life-threatening asthma, status asthmaticus, and near-fatal asthma. According to the 2007 National Asthma Education and Prevention Program guidelines, a life-threatening asthma exacerbation is marked by an inability to speak, a reduced peak expiratory flow rate of <25 % of a patient’s personal best, and a failed response to frequent bronchodilator administration and intravenous steroids. Almost all critical asthma syndrome cases require emergency care, and mos...
Source: Clinical Reviews in Allergy and Immunology - January 24, 2015 Category: Allergy & Immunology Source Type: research

Definition of Critical Asthma Syndromes
Abstract Urgent visits to the clinic and emergency department for acute severe asthma exacerbations are all too frequent. Existing national guidelines do not present consistent or specific recommendations for the evaluation and treatment of individual asthma patients in respiratory distress. In this vein, we propose the term "critical asthma syndrome" (CAS) to describe any child or adult who is at high risk for fatal asthma. Acute severe asthma, refractory asthma, status asthmaticus, and near-fatal asthma all describe CAS where physical exhaustion from the overwhelming work of breathing leads to respira...
Source: Clinical Reviews in Allergy and Immunology - January 24, 2015 Category: Allergy & Immunology Source Type: research

Am J Respir Crit Care Med; +29 new citations
29 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Respir Crit Care Med These pubmed results were generated on 2015/01/24PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - January 24, 2015 Category: Intensive Care Tags: Report Source Type: research

Radial artery applanation tonometry for continuous noninvasive arterial blood pressure monitoring in the cardiac intensive care unit
Conclusions In CICU patients, continuous noninvasive measurement of AP using radial artery applanation tonometry is feasible. The technology showed reasonable accuracy and precision in comparison with radial arterial catheter-derived AP values. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 24, 2015 Category: Cardiology Source Type: research

Does more than a single chest tube for mediastinal drainage affect outcomes after cardiac surgery?
CONCLUSION: The use of multiple mediastinal chest tubes after cardiac surgery confers no advantage over a single chest tube in preventing return to the operating room for bleeding or tamponade. PMID: 25598178 [PubMed - as supplied by publisher] (Source: Canadian Journal of Surgery)
Source: Canadian Journal of Surgery - January 24, 2015 Category: Surgery Authors: Le J, Buth KJ, Hirsch GM, Légaré JF Tags: Can J Surg Source Type: research

Predictors and Outcomes of Intensive Care Utilization in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant at Mayo Clinic, Florida
To understand predictors and outcomes of ICU admission we conducted a retrospective study of consecutive patients undergoing allogeneic HCT over a 10 year period 1/2002 - 12/2012. Information about patient demographics, disease characteristics, disease status, co-morbidities, conditioning regimen, donor characteristics and ICU interventions were collected. Single and multivariable analysis was used to assess associations between various characteristics and outcomes. Survival probabilities were estimated using the Kaplan-Meier method. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - January 24, 2015 Category: Hematology Authors: Demetria Ileana Jacks, Erin Mobley, Colleen Thomas, Laura Finn, James Foran, Vivek Roy Tags: Supportive Care Source Type: research

IMPACT of Chlorhexidine Bathing on Hospital-Acquired Infections and Skin Tolerance Among STEM CELL Transplant Patients
Central-line associated bloodstream infection (CLABSI) and Vancomycin-Resistant Enterococcus (VRE) colonization is not uncommon among Stem Cell Transplant (SCT) patients by nature of their underlying disease, immunodeficiency, and prolonged neutropenia. Chlorhexidine Gluconate (CHG) bathing has been extensively researched in the intensive care and medical/surgical units, but there is minimal literature regarding the oncology population, specifically SCT patients. Results of a literature review suggest that daily bathing with CHG may prevent hospital-acquired bloodstream infections and VRE colonization among SCT patients. (...
Source: Biology of Blood and Marrow Transplantation - January 24, 2015 Category: Hematology Authors: Clemen Banaglorioso Tags: Transplant Nursing Clinical Source Type: research

Evaluating for Acute Mesenteric Ischemia in Critically Ill Patients: Diagnostic Peritoneal Lavage is Associated With Reduced Operative Intervention and Mortality
The diagnosis of intra-abdominal pathology in the intensive care unit (ICU) patient, specifically acute mesenteric ischemia, necessitating operative intervention is considerably challenging. The mortality of acute mesenteric ischemia remains high, up to 90%. For this reason, rapid diagnosis and intervention are necessary. (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - January 24, 2015 Category: Emergency Medicine Authors: Justin Westphalen Tags: Abstract Source Type: research

Long-Term Outcomes After Severe Shock
This study supports the observation that acute illness severity does not determine long-term outcomes. Even extremely critically ill patients have similar outcomes to general intensive care unit survivor populations. (Source: Shock)
Source: Shock - January 24, 2015 Category: Emergency Medicine Tags: Clinical Aspects Source Type: research

Soluble RAGE and the RAGE Ligands HMGB1 and S100A12 in Critical Illness: Impact of Glycemic Control with Insulin and Relation with Clinical Outcome
ABSTRACT: Systemic inflammation often leads to complications in critically ill patients. Activation of the receptor for advanced glycation end-products (RAGE) generates inflammatory cytokines, proteases, and oxidative stress and may link inflammation to subsequent organ damage. Furthermore, hyperglycemia-induced oxidative stress increases RAGE ligands and RAGE expression. We hypothesized that preventing hyperglycemia during critical illness reduces the risk of excessively enhanced RAGE signaling, which could relate to clinical outcomes and risk of death. In 405 long-stay surgical intensive care unit patients randomized to ...
Source: Shock - January 24, 2015 Category: Emergency Medicine Tags: Clinical Aspects Source Type: research

Early versus delayed enteral feeding in patients with abdominal trauma: a retrospective cohort study
Conclusions Early enteral feeding administered within 72 h of SICU admission was associated with improved clinical outcomes without risk of increasing feeding intolerance in patients with abdominal trauma. Our results support the implementation of early enteral feeding in abdominal trauma management. (Source: European Journal of Trauma and Emergency Surgery)
Source: European Journal of Trauma and Emergency Surgery - January 24, 2015 Category: Emergency Medicine Source Type: research