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This page shows you the most recent publications within this specialty of the MedWorm directory.

Epidemiology, Risk Factors, Clinical Features, and Outcome of Adult Patients With Severe Pandemic A/H1N1/2009 Influenza in Qatar: A Retrospective Study
ConclusionsMost adult patients admitted with severe pandemic A/H1N1/2009 have one or more risk factors that increase their potential for a severe disease. Clinical features and laboratory finding are nonspecific and are similar to those reported by others, as well as hospital mortality. Being a smoker or having a high Acute Physiology and Chronic Heath Evaluation II score at admission increases the risk of death due to disease. Starting antiviral therapy as early as possible also increases the chance of survival. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - October 31, 2014 Category: Infectious Diseases Tags: Original Articles Source Type: research

Patient Outcomes on Day 4 of Intravenous Antibiotic Therapy in Non–Intensive Care Unit Hospitalized Adults With Community-Acquired Bacterial Pneumonia
ConclusionsIn this real-world chart study, less than half of hospitalized patients with CABP achieved clinical response at day 4 of initial intravenous antibiotic therapy. The observed clinical response was associated with a significantly shorter hospital stay and trended toward lower total hospital charges. These findings corroborate the Food and Drug Administration guidance for assessing antimicrobial therapy at day 4 because responder is associated with improved health outcomes. (Source: Infectious Diseases in Clinical Practice)
Source: Infectious Diseases in Clinical Practice - October 31, 2014 Category: Infectious Diseases Tags: Original Articles Source Type: research

Selective Reproduction: Social and Temporal Imaginaries for Negotiating the Value of Life in Human and Animal Neonates
This article employs a multi‐species perspective in investigating how life's worth is negotiated in the field of neonatology in Denmark. It does so by comparing decision‐making processes about human infants in the Danish neonatal intensive care unit with those associated with piglets who serve as models for the premature infants in research experiments within neonatology. While the comparison is unusual, the article argues that there are parallels across the decision‐making processes that shape the lives and deaths of infants and pigs alike. Collectivities or the lack thereof as well as expectations within linear or ...
Source: Medical Anthropology Quarterly - October 31, 2014 Category: Global & Universal Authors: Mette N. Svendsen Tags: Original Article Source Type: research

End-of-life matters in chronic renal failure
Purpose of reviewThe population considered eligible for dialysis has expanded dramatically over the past 4 decades, so that a significant proportion of patients receiving renal replacement therapy are elderly, frail and infirm. These patients have an extremely limited life expectancy and suffer from significant symptom burden, similar to patients with other end-stage organ failure or cancer. As dialysis has been offered more broadly, it is now initiated earlier than in decades past, further adding to cost and patient burden. Recent findingsThe trend toward more expansive and intensive care has not been corroborated by robu...
Source: Current Opinion in Supportive and Palliative Care - October 30, 2014 Category: Palliative Care Tags: END OF LIFE MANAGEMENT: Edited by Gustavo De Simone Source Type: research

Kangaroo care: cardio-respiratory relationships between the infant and caregiver
Kangaroo care, i.e., skin-to-skin cohabitation (SSC) between an infant and caregiver, is often used in neonatal intensive care units to promote bonding, breastfeeding and infant growth. The direct salutary effects of SSC on cardio-respiratory control in preterm infants remain equivocal; some reports suggest improved breathing stability, others indicate worsening of apnea, bradycardia and hypoxemia. (Source: Early Human Development)
Source: Early Human Development - October 30, 2014 Category: Perinatology & Neonatology Authors: Elisabeth Bloch-Salisbury, Ian Zuzarte, Premananda Indic, Francis Bednarek, David Paydarfar Source Type: research

Meta‐analysis of high‐ versus low‐chloride content in perioperative and critical care fluid resuscitation
ConclusionA weak but significant association between higher chloride content fluids and unfavourable outcomes was found, but mortality was unaffected by chloride content. (Source: British Journal of Surgery)
Source: British Journal of Surgery - October 30, 2014 Category: Surgery Authors: M. L. Krajewski, K. Raghunathan, S. M. Paluszkiewicz, C. R. Schermer, A. D. Shaw Tags: Systemetic review Source Type: research

Benzodiazepines in the ICU: Enough Is Enough!
Synopsis: In a review of a large intensive care unit (ICU) database, the use of propofol versus benzodiazepines for sedation was associated with lower mortality.Source: Lonardo NW, Mone MC, Nirula R, et al. Propofol is associated with improved outcomes compared with benzodiazepines in ventilated intensive care unit patients. Am J Respir Crit Care Med. 2014;189:1383–1394. (Source: Clinical Pulmonary Medicine)
Source: Clinical Pulmonary Medicine - October 30, 2014 Category: Respiratory Medicine Tags: Pulmonary Trends Source Type: research

Apnea after immunization of preterm infants
Objective: To determine the frequency of adverse reactions, particularly the occurrence of apnea, among preterm infants after immunization with diphtheria and tetanus toxoids and whole cell pertussis vaccine adsorbed (DTP) and Haemophilus influenzae type b conjugate (HibC) vaccine in the neonatal intensive care unit.Study design: After the occurrence of apnea in two preterm infants following immunization with DTP and HibC, a prospective surveillance of 97 preterm infants younger than 37 weeks of gestation who were immunized with DTP (94 also received HibC at the same time) in the neonatal intensive care unit was performed ...
Source: The Journal of Pediatrics - October 30, 2014 Category: Pediatrics Authors: Pablo J. Sánchez, Abbot R. Laptook, Linda Fisher, Janet Sumner, Richard C. Risser, Jeffrey M. Perlman Source Type: research

Assessing the Immune Status of Critically Ill Trauma Patients by Flow Cytometry
DiscussionWe suggest that flow cytometry is a research method that might aid nurse scientists in investigating the immune status of critically ill patients, the recovery status of conditions such as hemorrhagic shock and tissue injury and the relationship between cancer disease progression and symptoms. Therefore, flow cytometry has the potential to broaden nursing research priority areas so that a comprehensive approach to understanding the cellular response is attained. (Source: Nursing Research)
Source: Nursing Research - October 30, 2014 Category: Nursing Tags: Biology Review Source Type: research

A research protocol for testing relationships between nurse workload, missed nursing care and neonatal outcomes: the neonatal nursing care quality study
We describe an innovative research protocol to test the role of missed nursing care as a mediator of the association between nurse workload and patient outcomes in the neonatal intensive care unit. BackgroundIncreases in nurses' workloads are associated with adverse patient outcomes in neonatal intensive care settings. Missed nursing care is a frequently hypothesized explanation for the association between workload and outcomes. Few studies to date have tested missed care as a variable that mediates the workload–outcomes relationship. DesignWe use a longitudinal, observational study design. MethodsWe will recruit approxi...
Source: Journal of Advanced Nursing - October 30, 2014 Category: Nursing Authors: Heather L. Tubbs‐Cooley, Rita H. Pickler, Barbara A. Mark, Adam C. Carle Tags: Research Protocol Source Type: research

Prevalence and Perpetrators of Workplace Violence by Nursing Unit and the Relationship Between Violence and the Perceived Work Environment
ConclusionsThe prevalence and perpetrators of violence varied considerably among nursing units. Greater work demands and less trust and justice were associated with nurses’ experiences of violence. Clinical RelevanceAdequate work demands and a trusted and just work environment may reduce violence against nurses. In return, reduction of violence will contribute to creating a better nursing work environment. (Source: Journal of Nursing Scholarship)
Source: Journal of Nursing Scholarship - October 30, 2014 Category: Nursing Authors: Mihyun Park, Sung‐Hyun Cho, Hyun‐Ja Hong Tags: Original Manuscript Source Type: research

Cost‐benefit analysis of a delirium prevention strategy in the intensive care unit
ConclusionsA strategy is necessary for the delirium prevention of patients in the ICU to decrease the economic burden. Relevance to clinical practiceThis study demonstrated that a prevention strategy was cost‐effective because of its low input costs. With low additional investment, it is expected that this prevention strategy will be more available to other patients in the future. (Source: Nursing in Critical Care)
Source: Nursing in Critical Care - October 30, 2014 Category: Nursing Authors: Eunhee Lee, Jinhyun Kim Tags: Research Source Type: research

Intensive care in a general hospital: demographics, utilization and outcomes
Conclusion Critical care can be provided safely and in line with current best practice in smaller Irish hospitals. There is a cohort of patients for whom care may be best provided in a tertiary centre, how best to provide for these patients will likely be achieved by early identification (e.g. with SOFA score). Bed capacity issues remain problematic. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 30, 2014 Category: Journals (General) Source Type: research

Ethics of Drug Studies in the Newborn
This report describes some of the ethical challenges in conducting drug studies in pediatric patients that must be considered when planning studies and offers some solutions to meet those challenges. Methods of optimal study design should be utilized to limit the number of patients and the number of blood samples. Parental permission should be obtained with equipoise, although the parents of a sick newborn may feel an internal pressure for their child to participate in a study of a new and potentially superior therapy. If appropriate to the study, consent before labor and delivery when parents are less stressed is optimal....
Source: Pediatric Drugs - October 30, 2014 Category: Pediatrics Source Type: research

Ethics of Drug Research in the Pediatric Intensive Care Unit
This article addresses the main ethical issues specific to drug research in these critically ill children and proposes several solutions. The extraordinary environment of the PICU raises specific challenges to the design and conduct of research. The need for proxy consent of parents (or legal guardians) and the stress-inducing physical environment may threaten informed consent. The informed consent process is challenging because emergency research reduces or even eliminates the time to seek consent. Moreover, parental anxiety may impede adequate understanding and generate misconceptions. Alternative forms of consent have b...
Source: Pediatric Drugs - October 30, 2014 Category: Pediatrics Source Type: research

Serum sRAGE as a Potential Biomarker for Pediatric Bronchiolitis: A Pilot Study
Conclusions Serum sRAGE could be elevated in children with bronchiolitis. Larger clinical studies are necessary to elucidate its role as a bronchiolitis inflammatory and/or lung injury biomarker. (Source: Lung)
Source: Lung - October 30, 2014 Category: Respiratory Medicine Source Type: research

Computer-aided diagnostics in digital pathology: automated evaluation of early-phase pancreatic cancer in mice
Conclusions  Quantitative image analysis and classification were successful in preclinical histology diagnosis for early-stage pancreatic adenocarcinoma. The usage of annotated contours coupled with interpretable supervised learning methods and outlier pruning can be adapted to other medical imaging tasks. The usage of interpretable supervised learning techniques may improve the success of CAD in histopathological diagnosis. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - October 30, 2014 Category: Intensive Care Source Type: research

A statistical shape model of the human second cervical vertebra
Conclusion The SSM of the vertebra allows the shape variability of the C2 to be represented. Moreover, the SSM will enable semi-automatic segmentation and 3D model generation of the vertebra, which would greatly benefit surgery planning. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - October 30, 2014 Category: Intensive Care Source Type: research

A decade of extended‐criteria lung donors in a single center: was it justified?
Summary Despite a worldwide need to expand the lung donor pool, approximately 75% of lung offers are not accepted for transplantation. We investigated the impact of liberalizing lung donor acceptance criteria during the last decade on the number of effective transplants and early and late outcomes in our center. All 514 consecutive lung transplants (LTx) performed between Jan 2000 and Oct 2011 were included. Donors were classified as matching standard criteria (SCD; n = 159) or extended criteria (ECD; n = 272) in case they fulfilled at least one of the following criteria: age >55 years, PaO2/FiO2 at PEEP 5 cmH2O &...
Source: Transplant International - October 30, 2014 Category: Transplant Surgery Authors: Jana Somers, David Ruttens, Stijn E. Verleden, Bianca Cox, Alessia Stanzi, Elly Vandermeulen, Robin Vos, Bart M. Vanaudenaerde, Geert M. Verleden, Hans Van Veer, Willy Coosemans, Herbert Decaluwe, Philippe Nafteux, Paul De Leyn, Dirk E. Van Raemdonck Tags: Original Article Source Type: research

Nursing care in a high-technological environment: Experiences of critical care nurses
Management of technical equipment, such as ventilators, infusion pumps, monitors and dialysis, makes health care in an intensive care setting more complex. Technology can be defined as items, machinery and equipment that are connected to knowledge and management to maximise efficiency. Technology is not only the equipment itself, but also the knowledge of how to use it and the ability to convert it into nursing care. The aim of this study is to describe critical care nurses’ experience of performing nursing care in a high technology healthcare environment. (Source: Intensive and Critical Care Nursing)
Source: Intensive and Critical Care Nursing - October 30, 2014 Category: Nursing Authors: Adam Tunlind, John Granström, Åsa Engström Source Type: research

The extent and application of patient diaries in Australian intensive care units: A national survey
Critical illness can be a psychological stressor for patients and family members. Scandinavian studies have portrayed patient diaries as a supporting catalyst for patients and their families through a process of reflection and fact presentation. However, the small number of randomisation trials exhibits theoretical and methodological limitations. Given the increased interest amongst Australian Critical Care Nurses, further understanding of nurses’ perceptions and use of patient diaries was warranted. (Source: Australian Critical Care)
Source: Australian Critical Care - October 30, 2014 Category: Nursing Authors: Rajni Nair, Marion Mitchell, Samantha Keogh Tags: Research paper Source Type: research

Subarachnoid hemorrhage induces an early and reversible cardiac injury associated with catecholamine release: one-week follow-up study
IntroductionThe occurrence of cardiac dysfunction is common after subarachnoid haemorrhage (SAH) and was hypothesized to be related to the release of endogenous catecholamines. The aim of this prospective study was to evaluate the relationship between endogenous catecholamine and cardiac dysfunction at the onset and during the first week after SAH. Methods: Forty consecutive patients admitted for acute SAH without known heart disease were included. Catecholamine plasma concentrations and transthoracic echocardiography (TTE) were documented on admission, on day 1 (D1), and day 7 (D7). Results: At baseline, 24 patients had a...
Source: Critical Care - October 30, 2014 Category: Intensive Care Authors: Reda SalemFabrice ValléeFrançois DépretJacques CallebertJean Saint MauricePhilippe MartyJoaquim MatéoCatherine MadadakiEmmanuel HoudartDamien BressonSebastien FroelichChristian StapfDidier PayenAlexandre Mebazaa Source Type: research

A nationwide register‐based survey of baclofen toxicity
This article is protected by copyright. All rights reserved. (Source: Basic and Clinical Pharmacology and Toxicology)
Source: Basic and Clinical Pharmacology and Toxicology - October 29, 2014 Category: Drugs & Pharmacology Authors: Louise Bendix Kiel, Lotte Christine Groth Hoegberg, Tejs Jansen, John Asger Petersen, Kim Peder Dalhoff Tags: Original Article Source Type: research

A case of lethal spontaneous massive hemothorax in a patient with neurofibromatosis 1
Neurofibromatosis type 1 is an autosomal dominant disease characterized by multiple dermatological disorders amongst others. Among the less frequent manifestations are vascular abnormalities. Here, we present a case of spontaneous massive hemothorax in a 39-year-old Caucasian woman with neurofibromatosis 1 and a thoracic meningocele with a lethal outcome despite extensive surgical intervention as well as intensive care measures. Spontaneous hemothorax is a rare, but potentially lethal complication of neurofibromatosis type 1, which necessitates quick and decisive intervention; endovascular embolization where possible, othe...
Source: BioMed Central - October 29, 2014 Category: Journals (General) Authors: Luisa Zacarias FöhrdingTimur SellmannSebastian AngenendtDetlef Kindgen-MillesStefan A ToppBernhard KorbmacherArtur LichtenbergWolfram T Knoefel Source Type: research

Intracranial Pressure and Cerebrovascular Autoregulation in Pediatric Critical Illness
Protecting the brain in vulnerable infants and children with acute, critical illness involving the brain is a central aspect of pediatric intensive care and neurocritical care. Collectively, illness-induced derangements in intracranial pressure, circulatory homeostasis, and pressure autoregulation are all fundamental in informing bedside management. Therefore this review provides an understanding of these entities and a physiologic approach to bedside care and monitoring. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - October 29, 2014 Category: Neurology Authors: Robert C. Tasker Source Type: research

Comparison of the perceived image quality between two digital imaging systems for neonatal bedside radiography – A case study
Chest X-rays are performed daily in the neonatal intensive care and high care units. The skill of the radiographer is critical for obtaining the best image quality and limiting the patient's radiation exposure. The literature states that indirect flat panel detectors produce images of superior quality in comparison to computed radiography systems. At Steve Biko Academic Hospital a decision was made to revert from the direct digital radiography (DR) system to the computed radiography (CR) system, due to poor image quality experienced. (Source: Radiography)
Source: Radiography - October 29, 2014 Category: Radiology Authors: S.A. van Zyl, R.M. Kekana Source Type: research

Modern Trends in Infection Control Practices in Intensive Care Units
This article reviews the modern trends in infection control practices to prevent HAIs in ICUs with a focus on methods for monitoring hand hygiene, updates in isolation precautions, new methods for environmental cleaning, antimicrobial bathing, prevention of ventilator-associated pneumonia, central line-associated bloodstream infections, catheter-associated urinary tract infections, and Clostridium difficile infection. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Gandra, S., Ellison, R. T. Tags: Analytic Reviews Source Type: research

Massive Intravascular Hemolysis From Clostridium perfringens Septicemia: A Review
We describe the case of a patient with hemolysis-associated Clostridium perfringens septicemia and review all similar cases published in the literature since 1990, with specific focus on the relationship between treatment strategy and survival. We searched PubMed for all published cases of C. perfringens-associated hemolysis, using the medical subject terms "clostridia," "clostridial sepsis," and/or "hemolysis." All case reports, case series, review articles, and other relevant references published in the English literature since 1990 were included in this study. There were no exclusion criteria. Each case was examined wit...
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Simon, T. G., Bradley, J., Jones, A., Carino, G. Tags: Analytic Reviews Source Type: research

Common Anorectal Disorders for the Intensive Care Physician
This article will provide a brief review of anorectal anatomy, explain the proper anorectal examination, and discuss the current understanding and treatment concepts with regard to the most common anorectal disorders that the intensive care unit clinician is likely to face. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Bach, H. H., Wang, N., Eberhardt, J. M. Tags: Analytic Reviews Source Type: research

Retrospective Computed Tomography Mapping of Intrapleural Air May Demonstrate Optimal Window for Ultrasound Diagnosis of Pneumothorax
Conclusion: The CT scans demonstrate that intrapleural air most often collects along the mediastinum between ribs 3 and 6 on either side of the chest. Although no USs were performed in this retrospective study, one may infer that a parasternal approach along rib interspaces 3 to 6 is an easy and sensitive window to diagnose pneumothorax with US. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Kiley, S., Tighe, P., Hajibrahim, O., Deitte, L., Gravenstein, N., Robinson, A. Tags: Review of a Large Clinical Series Source Type: research

The Effect of the Pressure-Volume Curve for Positive End-Expiratory Pressure Titration on Clinical Outcomes in Acute Respiratory Distress Syndrome: A Systematic Review
Conclusion This analysis supports an association that ventilator management guided by the PVC for PEEP management may augment survival in ARDS. Nonetheless, only 3 randomized trials have addressed the question, and the total number of patients remains low. Further outcomes studies appear required for the validation of this methodology. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Hata, J. S., Togashi, K., Kumar, A. B., Hodges, L. D., Kaiser, E. F., Tessmann, P. B., Faust, C. A., Sessler, D. I. Tags: Review of a Large Clinical Series Source Type: research

The Prevalence and Impact of Mortality of the Acute Respiratory Distress Syndrome on Admissions of Patients With Ischemic Stroke in the United States
Conclusion: Our analysis demonstrates that ARDS is rare after AIS. Despite an overall significant reduction in mortality after AIS, ARDS carries a higher risk of death in this patient population. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Rincon, F., Maltenfort, M., Dey, S., Ghosh, S., Vibbert, M., Urtecho, J., Jallo, J., Ratliff, J. K., McBride, J. W., Bell, R. Tags: Original Research Source Type: research

Fever After Rewarming: Incidence of Pyrexia in Postcardiac Arrest Patients Who Have Undergone Mild Therapeutic Hypothermia
Conclusion: Among a cohort of patients who underwent mild TH after OHCA, more than half of these patients developed pyrexia in the first 24 hours after rewarming. Although there were no significant differences in outcomes between febrile and nonfebrile patients identified in this study, these findings should be further evaluated in a larger cohort. Future investigations may be needed to determine whether postrewarming temperature management will improve the outcomes in this population. (Source: Journal of Intensive Care Medicine)
Source: Journal of Intensive Care Medicine - October 29, 2014 Category: Intensive Care Authors: Cocchi, M. N., Boone, M. D., Giberson, B., Giberson, T., Farrell, E., Salciccioli, J. D., Talmor, D., Williams, D., Donnino, M. W. Tags: Original Research Source Type: research

Hyperlactatemia is an independent predictor of mortality and denotes distinct subtypes of severe sepsis and septic shock
Current guidelines and most trials do not consider elevated lactate serum concentrations when grading sepsis severity. We therefore assessed the association of different types of circulatory dysfunction regarding presence of hyperlactatemia and need for vasopressor support with clinical presentation and outcome of sepsis. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Daniel O. Thomas-Rueddel, Bernhard Poidinger, Manfred Weiss, Friedhelm Bach, Karin Dey, Helene Häberle, Udo Kaisers, Hendrik Rüddel, Dirk Schädler, Christian Scheer, Torsten Schreiber, Tobias Schürholz, Philipp Simon, Armin Sommerer, Daniel Schwarzkop Source Type: research

A Two-site Survey of Clinicians to Identify Practices and Preferences of Intensive Care Unit Transfers to General Medical Wards
The transfer of patients from the intensive care unit (ICU) to the general medical ward is high risk for adverse events and health care provider dissatisfaction. We aimed to identify perceived practices and what information is important to communicate during an ICU transfer. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Michael E. Detsky, Jonathan Ailon, Adina S. Weinerman, Andre C. Amaral., Chaim M. Bell Source Type: research

Nursing Intensive Care Skills Training; a nurse led, short, structured and practical training programme, developed and tested in a resource-limited setting
To assess the impact of a nurse led, short, structured training programme for intensive care unit (ICU) nurses in a resource-limited setting. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Pubudu De Silva, Tim Stephens, John Welch, Chathurani Sigera, Sunil De Alwis, Priyantha Athapattu, Dilantha Dharmagunawardene, Asela Olupeliyawa, Ashwini de Abrew, Lalitha Peiris, Somalatha Siriwardana, Indika Karunathilake, Arjen Dondorp, Rashan Haniffa Source Type: research

The Role of the Primary Care Team in the Rapid Response System
To evaluate the impact of primary service involvement on rapid response team (RRT) evaluations. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: John C. O’Horo, Ronaldo A. Sevilla-Berrios, Jennifer L. Elmer, Venu Velagapudi, Sean M. Caples, Rahul Kashyap, Jeffrey B. Jensen Source Type: research

Clinician perspectives on protocols designed to minimize sedation
Within a multicenter randomized trial comparing protocolized sedation with protocolized sedation plus daily interruption (DI), we sought perspectives of ICU clinicians regarding each strategy. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Louise Rose, Emma Fitzgerald, Deborah Cook, Scott Kim, Marilyn Steinberg, John W. Devlin, Betty Jean Ashley, Peter Dodek, Orla Smith, Kerri Poretta, Yoon Lee, Karen Burns, Johanne Harvey, Yoanna Skrobik, Dean Fergusson, Maureen Meade, Alan Kraguljac, Lisa Source Type: research

Characteristics and Outcomes of HIV-1-infected Patients with Acute Respiratory Distress Syndrome
We determined the prevalence of risk factors for the development of acute respiratory distress syndrome (ARDS), outcomes of critical illness, and the impact of HAART in HIV-1-infected patients. We hypothesized that in an urban county hospital, HIV-1-infected patients with ARDS would have a higher mortality than their HIV-1-uninfected counterparts. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Freny J. Nirappil, Ana Maheshwari, Joel Andrews, Greg S. Martin, Annette M. Esper, Sushma K. Cribbs Source Type: research

Insulin Infusion therapy in critical care patients: regular insulin VS. short acting insulin. A prospective, crossover, randomized, multicenter blind study
The aim of this multicenter, prospective, randomized, crossover trial is to compare, in critical care patients receiving insulin infusion therapy (IIT), the pharmacodynamic of Humulin insulin (Hlin), currently used as “standard of care”, and Humalog insulin (Hlog), a shorter acting insulin formulation. This was measured as extent and duration of the carryover effect of insulin treatment, with the latter calculated as ratio between blood glucose concentration (BGC) reduction during and after IIT. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Federico Bilotta, Rafael Badenes, Simona Lolli, Francisco Javier Belda, Sharon Einav, Giovanni Rosa Source Type: research

Developing a Percutaneous Dilatational Tracheostomy Service by Medical Intensivists: Experience at One Academic Institution
In this report, we describe our experience developing a PDT service led by medical intensivists. (Source: Journal of Critical Care)
Source: Journal of Critical Care - October 29, 2014 Category: Intensive Care Authors: Paresh C. Giri, Amy Bellinghausen Stewart, Vi A. Dinh, Ara A. Chrissian, H. Bryant Nguyen Source Type: research