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Intensive Care

This page shows you the most recent publications within this specialty of the MedWorm directory.

Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients
This study aimed to determine whether neutrophils that co-purify with PBMC express arginase, and if arginine depletion constrains T cell CD3 zeta-chain expression and function in human sepsis. Methods: Using flow cytometry, cell culture, HPLC, arginase activity and mRNA detection, our study examined whether neutrophils, with reduced buoyant density isolated in the Ficoll interface, metabolise L-arginine and suppress T cell proliferation in sepsis. A total of 35 sepsis patients (23 with septic shock) and 12 hospital controls in a tertiary referral hospital in tropical Australia were evaluated. Results: Only sepsis patients ...
Source: Critical Care - August 1, 2014 Category: Intensive Care Authors: Christabelle DarcyGabriela MinigoKim PieraJoshua DavisYvette McNeilYouwei ChenAlicia VolkheimerJ WeinbergNicholas AnsteyTonia Woodberry Source Type: research

Characteristics of the NICU Work Environment Associated With Breastfeeding Support.
CONCLUSIONS:: Nurses provide breastfeeding support around the clock. On a typical shift, about 1 in 7 NICU infants receives breastfeeding support from a nurse. Lactation consultants are not routinely available in NICUs, and their presence does not influence whether nurses provide breastfeeding support. Better nurse staffing fosters nurse provision of breastfeeding support. PMID: 25075926 [PubMed - as supplied by publisher] (Source: Adv Data)
Source: Adv Data - July 31, 2014 Category: Epidemiology Authors: Hallowell SG, Spatz DL, Hanlon AL, Rogowski JA, Lake ET Tags: Adv Neonatal Care Source Type: research

Compliance with prevention practices and their association with central line–associated bloodstream infections in neonatal intensive care units
We describe implementation and levels of compliance with preventive practices in a sample of US neonatal intensive care units (NICUs) and assess their association with CLABSI rates. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - July 31, 2014 Category: Infectious Diseases Authors: Philip Zachariah, E. Yoko Furuya, Jeffrey Edwards, Andrew Dick, Hangsheng Liu, Carolyn T.A. Herzig, Monika Pogorzelska-Maziarz, Patricia W. Stone, Lisa Saiman Tags: Major Articles Source Type: research

Central line–associated bloodstream infection in a trauma intensive care unit: Impact of implementation of Society for Healthcare Epidemiology of America/Infectious Diseases Society of America practice guidelines
This study aimed to assess the impact implementation of the basic Society for Healthcare Epidemiology of America/Infectious Diseases Society of America (SHEA/IDSA) practice recommendations in reducing central line–associated bloodstream infection (CLABSI) in intensive care units (ICUs). (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - July 31, 2014 Category: Infectious Diseases Authors: Waleed Mazi, Zikra Begum, Diaa Abdulla, Ahmed Hesham, Sami Maghari, Abdullah Assiri, Abiola Senok Tags: Major Articles Source Type: research

Epidemiology of pathogens and drug resistance of ventilator-associated pneumonia in Chinese neonatal intensive care units: A meta-analysis
Ventilator-associated pneumonia (VAP) is a common and serious problem in intensive care units. However, limited literature has been reviewed to synthesize the findings about the incidence, case fatality rate, pathogen distribution, and drug resistance of neonatal VAP in China. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - July 31, 2014 Category: Infectious Diseases Authors: Bin Tan, Xian Xian-Yang, Xian Zhang, Xi Peng-Zhou, Peng Wang, Jian Xue, Ya Ling-Huang, Ying Li-Li, Jing Fu-Qiu Tags: Major Articles Source Type: research

Ventilator-associated pneumonia: Survey of infection control practices in intensive care units of 15 tertiary care hospitals in Mumbai
Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality in patients hospitalized in intensive care units (ICUs). Meticulous implementation of infection control measures is a key component for reducing the incidence of VAP. The Society for Healthcare Epidemiology of America, Infectious Diseases Society of America, Association for the Profession of Infection Control and Epidemiology, and Centers for Disease Control and Prevention provide guidelines1-3 that comprehensively review the infection control measures for VAP prevention and provide evidence-based recommendations. (Source: American Journ...
Source: American Journal of Infection Control - July 31, 2014 Category: Infectious Diseases Authors: Vivek Bhat, Rohini Kelkar, Sanjay Biswas, Gita Natarajan Tags: Letters to the Editor Source Type: research

Critical care nurses' knowledge of measures to prevent ventilator-associated pneumonia
We queried critical care nurses at a hospital about their level of knowledge of interventions designed to prevent ventilator-associated pneumonia (VAP). The mean score was 7.87 ± 1.36 (65.6%) among 133 questionnaires. Multivariate analysis revealed that intensive care unit (ICU) license (P = .03) and ranking of registered nurses (RNs) (P = .041) were significantly associated with higher knowledge level (≥8 correct answers of 12 items) of respondents. This surveillance study revealed that non–ICU-licensed nurses and junior RNs lack the knowledge necessary to prevent VAP in critical care settings. (Source: American...
Source: American Journal of Infection Control - July 31, 2014 Category: Infectious Diseases Authors: Hsin-Lan Lin, Chih-Cheng Lai, Li-Yu Yang Tags: Brief Reports Source Type: research

Does the presence of oral care guidelines affect oral care delivery by intensive care unit nurses? A survey of Saudi intensive care unit nurses
This study aimed to evaluate the impact of oral care guidelines on the oral care delivered to mechanically ventilated patients by ICU nurses. A total of 215 nurses were enrolled. Demographic data and oral care practices were recorded through a self-administered survey. Participants governed by oral care guidelines had significantly higher oral care practice scores than their counterparts from ICUs without similar guidelines (P = .034; t = 2.13). (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - July 31, 2014 Category: Infectious Diseases Authors: Ahmed K. Alotaibi, Mohammed Alshayiqi, Sundar Ramalingam Tags: Brief Reports Source Type: research

Influence of signal colored hand disinfectant dispensers on hand hygiene compliance at a medical intensive care unit
To assess the influence of signal colors on hand disinfectant dispenser activities, health care workers (HCWs) at a medical intensive care unit were analyzed for a total of 20 weeks with 8 weeks before and 12 weeks after exchange to signal color. No significant increase in hand rubs (HRs) per patient day (PD) was observed (about 40 HRs/PD); however, HCW-adjusted compliance showed a 6% increase with signal colored devices. Therefore, colored devices may help to improve hand hygiene compliance. (Source: American Journal of Infection Control)
Source: American Journal of Infection Control - July 31, 2014 Category: Infectious Diseases Authors: Simone Scheithauer, Helga Häfner, Jörg Schröder, Katharina Nowicki, Sebastian Lemmen Tags: Brief Reports Source Type: research

Effects of prehospital adrenaline administration on out-of-hospital cardiac arrest outcomes: a systematic review and meta-analysis
Conclusions: Prehospital adrenaline administration may increase prehospital return of spontaneous circulation, but it does not improve overall rates of return of spontaneous circulation, hospital admission and survival to discharge. (Source: Critical Care)
Source: Critical Care - July 31, 2014 Category: Intensive Care Authors: Pongsakorn AtiksawedparitSasivimol RattanasiriMark McEvoyColin GrahamYuwares SittichanbunchaAmmarin Thakkinstian Source Type: research

Early prediction of new-onset physical disability after intensive care unit stay: a preliminary instrument
Conclusions: Educational level is the single most important predictor for new-onset physical disability 2?months after ICU stay, followed by impaired core stability at ICU discharge, the presence of fractures and ICU stay longer than 2?days. A simple screening instrument based on these predictors can be used at ICU discharge to determine the risk for new-onset physical disability. This preliminary instrument may help clinicians to identify patients in need of support, but needs external validation prior to wider clinical use. (Source: Critical Care)
Source: Critical Care - July 31, 2014 Category: Intensive Care Authors: Anna SchandlMatteo BottaiUlrika HoldarElisabeth HellgrenPeter Sackey Source Type: research

Mortality in severely injured children: experiences of a German level 1 trauma center (2002 - 2011)
Conclusions: Head trauma is the determinant factor for mortality in severely injured pediatric patients. Death occurred shortly after arrival and long term intensive care stays might be an exception. In treatment of severely injured children volume management, hemorrhage and coagulopathy management, rescue time, and total surgery time should receive more attention. (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - July 30, 2014 Category: Pediatrics Authors: Carsten SchoenebergMarc SchillingJudith KeitelManuel BurggrafBjoern HussmannSven Lendemans Source Type: research

Clinical features, treatment and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis A multinational, multicenter study of 362 patients
Conclusion. This study provides information on the clinical spectrum and current management of sJIA‐associated MAS through the analysis of a very large patient sample. MAS remains a serious condition as a sizeable proportion of patients required ICU admission or died. © 2014 American College of Rheumatology. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - July 30, 2014 Category: Rheumatology Authors: Francesca Minoia, Sergio Davì, AnnaCarin Horne, Erkan Demirkaya, Francesca Bovis, Caifeng Li, Kai Lehmberg, Sheila Weitzman, Antonella Insalaco, Carine Wouters, Susan Shenoi, Graciela Espada, Seza Ozen, Jordi Anton, Raju Khubchandani, Ricardo Russo, Priy Tags: Full Length Source Type: research

Cardiac arrest patients have an impaired immune response, which is not influenced by induced hypothermia
Induced hypothermia after cardiac arrest does not alter immune response when compared with patients with a body temperature regulated at 36°C, contradicting fears that induced hypothermia may increase the risk of infection. (Source: Critical Care)
Source: Critical Care - July 30, 2014 Category: Intensive Care Authors: Charlotte BeurskensJanneke HornAnita de BoerMarcus SchultzEster van LeeuwenMargreeth VroomNicole Juffermans Source Type: research

Management and outcome of 35 cases with foetal/neonatal alloimmune neutropenia
ConclusionMore than half (21) of the 35 cases of FNAIN presented with infections and most implicated were HNA‐1a, HNA‐1b and HNA‐2. Treatment with antibiotics seemed adequate. A neonatal neutropenia workflow model for use in neonatal intensive care units is presented. (Source: Acta Paediatrica)
Source: Acta Paediatrica - July 29, 2014 Category: Pediatrics Authors: Rita Tooren‐de Groot, Mark Ottink, Elly Huiskes, André Rossum, Bibian Voorn, Jennichjen Slomp, Masja Haas, Leendert Porcelijn Tags: Regular Article Source Type: research

Sticking to minimum standards: implementing antibiotic stewardship in intensive care
ConclusionA systematic approach to quality improvement combined with the implementation of a tailored, multi‐faceted intervention can improve antimicrobial prescribing practices. (Source: Internal Medicine Journal)
Source: Internal Medicine Journal - July 29, 2014 Category: Internal Medicine Authors: Nadia J Chaves, Robyn J Ingram, Christopher M MacIsaac, Kirsty L Buising Tags: Original Article Source Type: research

Glucose control in intensive care: usability, efficacy and safety of Space GlucoseControl in two medical European intensive care units
Background: The Space GlucoseControl system (SGC) is a nurse-driven, computer-assisted device for glycemic control combining infusion pumps with the enhanced Model Predictive Control algorithm (B. Braun, Melsungen, Germany). We aimed to investigate the performance of the SGC in medical critically ill patients. Methods: Two open clinical investigations in tertiary centers in Graz, Austria and Zurich, Switzerland were performed. Efficacy was assessed by percentage of time within the target range (4.4-8.3 mmol/L; primary end point), mean blood glucose, and sampling interval. Safety was assessed by the number of hypoglycemic e...
Source: Epidemiologic Perspectives and Innovations - July 29, 2014 Category: Epidemiology Authors: Karin AmreinNorman KachelHeike FriesRoman HovorkaThomas R PieberJohannes PlankUrs WengerBarbara LienhardtMarco Maggiorini Source Type: research

Lung transplantation from donors outside standard acceptability criteria – are they really marginal?
ConclusionCarefully selected donor lungs from outside the standard acceptability criteria may expand existing donor pool with no detrimental effect on LTx outcome.This article is protected by copyright. All rights reserved. (Source: Transplant International)
Source: Transplant International - July 29, 2014 Category: Transplant Surgery Authors: Bartlomiej Zych, Diana García Sáez, Anton Sabashnikov, Fabio De Robertis, Mohamed Amrani, Toufan Bahrami, Prashant N. Mohite, Nikhil P. Patil, A. Weymann, Aron F. Popov, Anna Reed, Martin Carby, André R. Simon Tags: Original Article Source Type: research

Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome
Background: Abdominal infections are frequent causes of sepsis and septic shock in the intensive care unit (ICU) and are associated with adverse outcomes. We analyzed the characteristics, treatments and outcome of ICU patients with abdominal infections using data extracted from a one-day point prevalence study, the Extended Prevalence of Infection in the ICU (EPIC) II. Methods: EPIC II included 13,796 adult patients from 1,265 ICUs in 75 countries. Infection was defined using the International Sepsis Forum criteria. Microbiological analyses were performed locally. Participating ICUs provided patient follow-up until hospita...
Source: BMC Infectious Diseases - July 29, 2014 Category: Infectious Diseases Authors: Jan De WaeleJeffrey LipmanYasser SakrJohn MarshallPhilippe VanhemsCasiano Barrera GrobaMarc LeoneJean-Louis Vincent Source Type: research

Decision Aids for Advance Care Planning: An Overview of the State of the Science.
Abstract Advance care planning honors patients' goals and preferences for future care by creating a plan for when illness or injury impedes the ability to think or communicate about health decisions. Fewer than 50% of severely or terminally ill patients have an advance directive in their medical record, and physicians are accurate only about 65% of the time when predicting patient preferences for intensive care. Decision aids can support the advance care planning process by providing a structured approach to informing patients about care options and prompting them to document and communicate their preferences. This...
Source: Annals of Internal Medicine - July 29, 2014 Category: Internal Medicine Authors: Butler M, Ratner E, McCreedy E, Shippee N, Kane RL Tags: Ann Intern Med Source Type: research

Blockade of the Programmed Death-1 Pathway Restores Sarcoidosis CD4+ T Cells Proliferative Capacity.
Conclusions: Analogous to the effects in other chronic lung diseases, these findings demonstrate that the PD-1 pathway is an important contributor to sarcoidosis CD4+ T cell proliferative capacity and clinical outcome. Blockade of the PD-1 pathway may be a viable therapeutic target to optimize clinical outcomes. PMID: 25073001 [PubMed - as supplied by publisher] (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - July 29, 2014 Category: Intensive Care Authors: Braun NA, Celada LJ, Herazo-Maya JD, Abraham S, Shaginurova G, Sevin CM, Grutters J, Culver DA, Dworski R, Sheller J, Massion PP, Polosukhin VV, Johnson JE, Kaminski N, Wilkes DS, Oswald-Richter KA, Drake WP Tags: Am J Respir Crit Care Med Source Type: research

Life-Threatening Events During Endurance Sports Is Heat Stroke More Prevalent Than Arrhythmic Death?
ConclusionsIn our cohort of athletes participating in endurance sports, for every serious cardiac adverse event, there were 10 serious events related to heat stroke. One of the heat stroke–related fatalities presented with unheralded cardiac arrest. Our results put in a different perspective the ongoing debate about the role of pre-participation electrocardiographic screening for the prevention of sudden death in athletes. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - July 28, 2014 Category: Cardiology Source Type: research

A Few Minutes With Richard Cuming
I became interested in perioperative nursing as a critical-care nurse; I felt that a better understanding of what happened to my patients as I pushed them through those double doors would make me a better intensive care unit nurse. I never expected to love the OR as much as I did, much less have a 17-year career there! Currently I am the chief nursing executive at the Einstein Healthcare Network in Philadelphia, Pennsylvania, where I am responsible for nursing practice across the system. Serving on the Editorial Board of the AORN Journal helps me to stay connected to my clinical passion and also to give back to AORN. (Source: AORN Journal)
Source: AORN Journal - July 28, 2014 Category: Nursing Authors: Richard Cuming Tags: Editorial Board Outlook Source Type: research

The development of a specialty: an interview with Dr. Mark C. Rogers, a pioneering pediatric intensivist
Summary Dr. Mark C. Rogers (1942–), Professor of Anesthesiology, Critical Care Medicine, and Pediatrics at the Johns Hopkins University, was recruited by the Department of Pediatrics at Johns Hopkins Hospital in 1977 to become the first director of its pediatric intensive care unit. After the dean of the medical school appointed him to chair the Department of Anesthesia in 1979, Rogers changed the course and culture of the department. He renamed it the Department of Anesthesiology and Critical Care Medicine, and developed a long‐term strategy of excellence in clinical care, research, and education. However, throughout ...
Source: Pediatric Anesthesia - July 28, 2014 Category: Anesthesiology Authors: Christine L. Mai, Paul G. Firth, Zulfiqar Ahmed, Samuel Rodriguez, Myron Yaster Tags: History of Pediatric Anesthesia Timeline Source Type: research

Early mobilization on continuous renal replacement therapy is safe and may improve filter life
Conclusions: Mobilization during renal replacement therapy via a vascular catheter in patients who are critically ill is safe and may increase filter life. These findings have significant implications for the current mobility restrictions imposed on patients with femoral vascular catheters for renal replacement therapy.Trial registration: Australian and New Zealand Clinical Trials Registry ACTRN12611000733976. Registered 13 July 2011. (Source: Critical Care)
Source: Critical Care - July 28, 2014 Category: Intensive Care Authors: Yi Tian WangTerry HainesPaul RitchieCraig WalkerTeri AnsellDanielle RyanPhaik-Sim LimSanjiv VijRebecca AcsNigel FealyElizabeth Skinner Source Type: research

Early non‐invasive ventilation treatment for respiratory failure due to severe community‐acquired pneumonia
ConclusionsSuccessful treatment is strongly related to less severe illness as well as to a good initial and sustained response to medical therapy and NIV treatment. Constant monitoring of these patients is mandatory. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - July 28, 2014 Category: Respiratory Medicine Authors: Antonello Nicolini, Gianluca Ferraioli, Maura Ferrari‐Bravo, Cornelius Barlascini, Mario Santo, Lorenzo Ferrera Tags: Original Article Source Type: research

Gleaning Knowledge from Data in the ICU.
Abstract It is often difficult to accurately predict who, when and why patients develop shock because signs of shock often occur late once organ injury is already present. Three levels of aggregation of information can be used to aid the bedside clinician in this task: analysis of derived parameters of existing measured physiologic variables using simple bedside calculations (Functional Hemodynamic Monitoring), using prior physiologic data of similar subjects during periods of stability and disease to define quantitative metrics of level of severity; and to use libraries of responses across large and comprehensive ...
Source: Am J Respir Crit Car... - July 28, 2014 Category: Intensive Care Authors: Pinsky MR, Dubrawski A Tags: Am J Respir Crit Care Med Source Type: research

Nontuberculous Mycobacteria among Cystic Fibrosis Patients in the United States: Screening Practices and Environmental Risk.
Conclusions: NTM prevalence varies significantly among CF patients by geographic area, and is largely influenced by environmental factors. However, NTM culture practices vary greatly, with some high-prevalence states screening <25% annually. Routine screening for all CF patients is needed for timely detection. PMID: 25068291 [PubMed - as supplied by publisher] (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - July 28, 2014 Category: Intensive Care Authors: Adjemian J, Olivier KN, Prevots DR Tags: Am J Respir Crit Care Med Source Type: research

Prophylactic Oral Health Procedures to Prevent Hospital-Acquired and Ventilator-Associated Pneumonia: A Systematic Review
Given the severity of hospital-acquired pneumonia and ventilator-associated pneumonia, the purpose of this systematic review was to identify various oral health procedures, in intensive care unit or nursing home setting, shown to help reduce the incidence of hospital-acquired and ventilator-associated pneumonia. (Source: International Journal of Nursing Studies)
Source: International Journal of Nursing Studies - July 27, 2014 Category: Nursing Authors: Mohamed El-Rabbany, Noha Zaghlol, Mohit Bhandari, Amir Azarpazhooh Source Type: research

Prospective evaluation of the International Study Group for Liver Surgery definition of bile leak after a liver resection and the role of routine operative drainage: an international multicentre study
ConclusionThe ISGLS definition of bile leak after liver surgery appears robust and intra‐operative drain usage did not prevent the need for subsequent drain placement. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - July 26, 2014 Category: Gastroenterology Authors: Mark Brooke‐Smith, Joan Figueras, Shahid Ullah, Myrddin Rees, Jean‐Nicolas Vauthey, Thomas J. Hugh, O. James Garden, S.T. Fan, Michael Crawford, Masatoshi Makuuchi, Yukihiro Yokoyama, Marcus Büchler, Juergen Weitz, Robert Padbury Tags: Original Article Source Type: research

The quality of intensive care unit nurse end of life handover: An international study
Quality ICU end-of-life-care has been found to be related to good communication. Handover is one form of communication that can be problematic due to lost or omitted information. A first step in improving care is to measure and describe it. (Source: International Journal of Nursing Studies)
Source: International Journal of Nursing Studies - July 26, 2014 Category: Nursing Authors: Freda DeKeyser Ganz, Ruth Endacott, Wendy Chaboyer, Julie Benbinishty, Maureen Ben Nun, Helen Ryan, Amanda Schoter, Carole Boulanger, Wendy Chamberlain, Amy Spooner Source Type: research

Frequency of dosage prescribing medication errors associated with manual prescriptions for very preterm infants
This study aimed to evaluate the rate of dosage PME related to manual prescriptions in the high‐risk population of very preterm infants (GA < 33 weeks) in a mixed prescription system. MethodsThe study was based on a retrospective review of a random sample of manual daily prescriptions in two neonatal intensive care units (NICU) A and B, located in different French University hospitals (Dijon and La Reunion island). Daily prescription was defined as the set of all drugs manually prescribed on a single day for one patient. Dosage error was defined as a deviation of at least ±10% from the weight‐appropriate recomme...
Source: Journal of Clinical Pharmacy and Therapeutics - July 25, 2014 Category: Drugs & Pharmacology Authors: J. Horri, A. Cransac, C. Quantin, M. Abrahamowicz, C. Ferdynus, C. Sgro, P.‐Y. Robillard, S. Iacobelli, J.‐B. Gouyon Tags: Original Article Source Type: research

Self-reported attitudes versus actual practice of oxygen therapy by ICU physicians and nurses
Conclusions: Most ICU clinicians acknowledge the potential adverse effects of prolonged exposure to hyperoxia and report a low tolerance for high oxygen levels. However, in actual clinical practice, a large proportion of their ICU patients was exposed to higher arterial oxygen levels than self-reported target ranges. (Source: BioMed Central)
Source: BioMed Central - July 25, 2014 Category: Journals (General) Authors: Hendrik HelmerhorstMarcus J SchultzPeter van der VoortRobert J BosmanNicole P JuffermansEvert de JongeDavid J van Westerloo Source Type: research

Psychometric comparison of three behavioural scales for the assessment of pain in critically ill patients unable to self-report
The Behavioural Pain Scale and Critical Care Pain Observation Tool show the best reliability and consistency for assessing pain in ICU patients.  (Source: Critical Care)
Source: Critical Care - July 25, 2014 Category: Intensive Care Authors: Gerald ChanquesAnne PohlmanJohn KressNicolas MolinariAudrey de JongSamir JaberJesse Hall Source Type: research

Anaesthetic management of cytoreductive surgery followed by hyperthermic intrathoracic chemotherapy perfusion
Conclusion: This article summarizes important experiences of the anaesthesiological and intensive care management in patients undergoing HITHOC. (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - July 25, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Christoph KerscherMichael RiedHans-Stefan HofmannBernhard GrafYork Zausig Source Type: research

A Systematic Review of Amniotic Fluid Assessments in Twin Pregnancies
The objectives of this systematic review were to examine the reproducibility of sonographic estimates of amniotic fluid volume (AFV) in twin pregnancies, compare the association of sonographic estimates of AFV with dye-determined AFV, and correlate AFV with antepartum, intrapartum, and perinatal outcomes in twin pregnancies. Studies were included if they were adequately powered and investigated antepartum, intrapartum, and/or perinatal adverse outcome parameters in twin gestations. Studies with comparable populations and exclusion criteria were merged into forest plots. Data comparing the accuracy of AFV assessment, correl...
Source: Journal of Ultrasound in Medicine - July 25, 2014 Category: Radiology Authors: Ippolito, D. L., Bergstrom, J. E., Lutgendorf, M. A., Flood-Nichols, S. K., Magann, E. F. Tags: Review Articles Source Type: research

Real-time Sonographically Guided Percutaneous Dilatational Tracheostomy Using a Long-Axis Approach Compared to the Landmark Technique
Conclusions— Percutaneous dilatational tracheostomy under real-time sonographic guidance using a long-axis approach may increase the rate of midline punctures and decrease the number of needle punctures when compared to the landmark technique. Sonographic guidance can also help guide accurate and efficient placement of a tracheostomy tube into the desired tracheal ring space. (Source: Journal of Ultrasound in Medicine)
Source: Journal of Ultrasound in Medicine - July 25, 2014 Category: Radiology Authors: Dinh, V. A., Farshidpanah, S., Lu, S., Stokes, P., Chrissian, A., Shah, H., Giri, P., Hecht, D., Nguyen, H. B. Tags: Original Research Source Type: research

Impact of duration of critical illness on the adrenal glands of human intensive care patients.
Conclusion and Relevance: Lipid depletion and reduced ACTH-regulated gene expression in prolonged critical illness suggest that sustained lack of ACTH may contribute to risk of adrenal insufficiency in long-stay ICU patients. PMID: 25062464 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 25, 2014 Category: Endocrinology Authors: Boonen E, Langouche L, Janssens T, Meersseman P, Vervenne H, De Samblanx E, Pironet Z, Van Dijck L, Vander Perre S, Derese I, Van den Berghe G Tags: J Clin Endocrinol Metab Source Type: research

The use of ultrasound‐guided regional anaesthetic techniques in neonates and young infants
Optimal pain therapy during the perioperative period or at the neonatal intensive care unit and subsequent reduced use of opioids and various sedative drugs is an important factor for patients care. The use of various regional anaesthetic techniques in experienced hands provides excellent pain relief and has the potency to reduce the requirement for perioperative mechanical ventilation. Most of regional anaesthesia techniques are applicable also in neonates and young infants and can be used in an effective and safe manner. Ultrasound guidance should be used for all regional anaesthetic techniques to increase efficacy and s...
Source: Acta Anaesthesiologica Scandinavica - July 24, 2014 Category: Anesthesiology Authors: P. MARHOFER, P.‐A. LÖNNQVIST Tags: Review Article Source Type: research

Critical congenital heart disease screening by pulse oximetry in a neonatal intensive care unit
minrusimha (Source: Journal of Perinatology)
Source: Journal of Perinatology - July 24, 2014 Category: Perinatology & Neonatology Authors: V ManjaB MathewV CarrionS Lakshminrusimha Source Type: research

The effect of facilitated tucking on procedural pain control among premature babies
ConclusionsFacilitated tucking reduced the Premature Infant Pain Profile scores in preterm infants. Relevance to clinical practiceThe findings of this study suggest that facilitated tucking is able to alleviate pain; therefore, nurses must be able to carry out facilitated tucking when necessary. (Source: Journal of Clinical Nursing)
Source: Journal of Clinical Nursing - July 24, 2014 Category: Nursing Authors: Olive Lopez, Pathmawathi Subramanian, Norsiah Rahmat, Lim Chin Theam, Karuthan Chinna, Roshaslina Rosli Tags: Original Article Source Type: research

Molecular screening of carbapenemase - producing gram negative strains in romanian intensive care units during one year survey.
MOLECULAR SCREENING OF CARBAPENEMASE - PRODUCING GRAM NEGATIVE STRAINS IN ROMANIAN INTENSIVE CARE UNITS DURING ONE YEAR SURVEY. J Med Microbiol. 2014 Jul 24; Authors: Gheorghe I, Czobor I, Chifiriuc MC, Borcan E, Ghiță C, Banu O, Lazăr V, Mihăescu G, Mihăilescu DF, Zhiyong Z Abstract This is the first study performed on a significant number of strains (79 carbapenem resistant Enterobacteriaceae and 84 carbapenem resistant non-fermenting Gram negative rods) recently isolated from the intensive care units of two big hospitals from Bucharest, the capital city of Romania. The obtained results revealed...
Source: Journal of Medical Microbiology - July 24, 2014 Category: Microbiology Authors: Gheorghe I, Czobor I, Chifiriuc MC, Borcan E, Ghiță C, Banu O, Lazăr V, Mihăescu G, Mihăilescu DF, Zhiyong Z Tags: J Med Microbiol Source Type: research

Interventions to Reduce Medication Errors in Pediatric Intensive Care.
CONCLUSIONS: Available evidence suggests some aspects of CPOE with decision support, ME, and IS may help in reducing medication errors. Good quality, prospective, observational studies are needed for institutions to determine the most effective interventions. PMID: 25059205 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - July 24, 2014 Category: Drugs & Pharmacology Authors: Manias E, Kinney S, Cranswick N, Williams A, Borrott N Tags: Ann Pharmacother Source Type: research

Sedation and its psychological effects following intensive care.
Abstract Significant psychological impacts, including post-traumatic stress disorder (PTSD), have been associated with patients under sedation in intensive care units (ICUs). However, it remains unknown if and how sedation is related to post-ICU psychological outcomes. This literature review explores the relationships between sedation, the depth of sedation and psychological disorders. A review of existing literature was undertaken systematically with key terms and included peer-reviewed primary research and randomised controlled trials (RCTs). To ensure subject relevance pre-2006, non-English and paediatric-based ...
Source: British Journal of Nursing - July 24, 2014 Category: Nursing Authors: Croxall C, Tyas M, Garside J Tags: Br J Nurs Source Type: research

Effectiveness of a patient education intervention in enhancing the self-efficacy of hospitalized patients to recognize and report acute deteriorating conditions
Early detection of physiological deterioration has been recognized as essential to prevent adverse events including unexpected admissions to the intensive care units, cardiac arrests and deaths [1]. As part of an integrated system of care known as the Rapid Response System (RRS), strategies such as the early warning scores, critical care outreach teams and educational programmes for medical doctors and ward nurses have been implemented in many acute hospitals with the aim to improve care of patients with deteriorating conditions [2,3]. (Source: Patient Education and Counseling)
Source: Patient Education and Counseling - July 24, 2014 Category: Global & Universal Authors: Min Ting Alicia See, Wai-Chi Sally Chan, Paul John Huggan, Yee Kian Tay, Sok Ying Liaw Source Type: research

Experimental and clinical evidences for glucose control in intensive care: is infused glucose the key point for study interpretation?
Stress-induced hyperglycemia has been considered an adaptive mechanism to stress up to the first intensive insulin therapy trial, which showed a 34% reduction in relative risk of in-hospital mortality when normalizing blood glucose levels. Further trials had conflicting results and, at present, stress-induced hyperglycemia management remains non-consensual. These findings could be explained by discrepancies in trials, notably regarding the approach to treat hyperglycemia: high versus restrictive caloric intake. Stress-induced hyperglycemia is a frequent complication during intensive care unit stay and is associated with a ...
Source: Critical Care - July 23, 2014 Category: Intensive Care Authors: Aurélien MazeraudAndrea PolitoDjillali Annane Source Type: research

Interest of low-dose hydrocortisone therapy during brain-dead organ donor resuscitation: the CORTICOME study
Conclusions: Despite no observed benefits of the steroid administration on primary function recovery of transplanted grafts, administration of glucocorticoids should be a part of the resuscitation management of deceased donors with hemodynamic instability. (Source: Critical Care)
Source: Critical Care - July 23, 2014 Category: Intensive Care Authors: Michel PinsardStéphanie RagotPaul MertesJean BleichnerSamira ZitouniFabrice CookMarc PierrotLaurent DubeEdgard MenguyLaurent LefèvreLaurence EscaravagePierre-François DequinPhilippe VignonNicolas Pichon Source Type: research