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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.

Elective non-therapeutic intensive care and the four principles of medical ethics
The chronic worldwide lack of organs for transplantation and the continuing improvement of strategies for in situ organ preservation have led to renewed interest in elective non-therapeutic ventilation of potential organ donors. Two types of situation may be eligible for elective intensive care: patients definitely evolving towards brain death and patients suitable as controlled non-heart beating organ donors after life-supporting therapies have been assessed as futile and withdrawn. Assessment of the ethical acceptability and the risks of these strategies is essential. We here offer such an ethical assessment using the fo...
Source: Journal of Medical Ethics - February 18, 2013 Category: Medical Ethics Authors: Baumann, A., Audibert, G., Lafaye, C. G., Puybasset, L., Mertes, P.-M., Claudot, F. Tags: Cardiovascular medicine, End of life decisions (geriatric medicine), End of life decisions (palliative care), Adult intensive care, Artificial and donated transplantation, End of life decisions (ethics), Legal and forensic medicine Elective ventilation Source Type: research

Ventilating the debate: elective ventilation revisited
This issue of the Journal of Medical Ethics features a special symposium on ‘elective ventilation’ (EV). EV (also known as ‘non-therapeutic ventilation’ (box 1)) was originally described in the 1990s by doctors working in Exeter in the UK.1 At that time there was concern about the large shortfall in organs for transplantation. Patients could become organ donors if they were diagnosed as being brain dead, but this only ever occurred in patients on breathing machines in intensive care who developed signs of brainstem failure. Doctors wondered if there were patients dying outside intensive care who, if...
Source: Journal of Medical Ethics - February 18, 2013 Category: Medical Ethics Authors: Wilkinson, D. Tags: Editorial Source Type: research

Systematic review and meta-analysis finds newer hydroxyethyl starch to be of no overall clinical benefit in sepsis
Source: British Medical Journal (BMJ) Area: News According to the results of a systematic review and meta-analysis, treatment of sepsis with newer hydroxyethyl starches increases the risk of having renal replacement therapy, red blood cell transfusion, and severe adverse reactions when compared to crystalloids or human albumin, and is therefore unlikely to be of benefit for this patient group. The authors note that colloids are used more often than crystalloids for resuscitation in the intensive care unit (ICU). Although the choice of colloid varies between countries, hydroxyethyl starch is most commonly used w...
Source: NeLM - News - February 18, 2013 Category: Drugs & Pharmacology Source Type: news

Topical nystatin prophylaxis: a likely viable measure for reducing impact of candidaemia in neurosurgical patient with early tracheostomy intubation.
Oral and tracheostomy site brushing with topical nystatin could be a usefull prophylaxis to reduce the incidence of Candida spp. bloodstream infection in neurosurgical ICU patients that underwent to early tracheostomy intubation.
Source: Critical Care - February 18, 2013 Category: Intensive Care Authors: Giancarlo CeccarelliSimone GiulianoMarco FalconeMario Venditti Source Type: research

Correction: Does artificial nutrition improve outcome of critical illness?
After publication of their articlE, the authors noticedtwo errors in their viewpoint.
Source: Critical Care - February 18, 2013 Category: Intensive Care Authors: Michael CasaerGreet Van den BergheMiet Schetz Source Type: research

Susceptibility of bacterial etiological agents to commonly-used antimicrobial agents in children with sepsis at the Tamale Teaching Hospital
Conclusion: Coagulase Negative, Coagulase Positive Staphylococci, Salmonella and Klebsiella were the aetiological agents of bloodstream infection among children at TTH. While gram-positive and gram-negative bacteria showed low susceptibility to Ampicillin, Tetracycline and Cotrimoxazole, the GNR were susceptible to Gentamicin and third-generation cephalosporins.
Source: BMC Infectious Diseases - February 18, 2013 Category: Infectious Diseases Authors: Samuel AcquahLawrence QuayeKenneth SagoeJuventus ZiemPatricia BrombergerAnthony Amponsem Source Type: research

Prognosis of generalized bullous fixed drug eruption: comparison with Stevens–Johnson syndrome and toxic epidermal necrolysis
Conclusions Although our study featured limited statistical power, we were not able to confirm that GBFDE had better prognosis than SJS or SJS/TEN of similar disease extent in older patients. Severe cases of GBFDE deserve the attention and active management given to patients with SJS or TEN.
Source: British Journal of Dermatology - February 16, 2013 Category: Dermatology Authors: S. Lipowicz, P. Sekula, S. Ingen‐Housz‐Oro, Y. Liss, B. Sassolas, A. Dunant, J.‐C. Roujeau, M. Mockenhaupt Tags: CLINICAL AND LABORATORY INVESTIGATIONS Source Type: research

Stage one Norwood procedure in an emerging economy:Initial experience in a single center
Conclusions:Stage one Norwood is feasible in a limited-resource environment if supported by a dedicated postoperative intensive care and protocolized nursing management. Preoperative optimization and prevention of infections are major challenges in addition to preventing early circulatory collapse.
Source: Annals of Pediatric Cardiology - February 16, 2013 Category: Cardiology Authors: Rakhi BalachandranSuresh G NairSunil S GopalrajBalu VaidyanathanBrijesh P KottayilRaman Krishna Kumar Source Type: research

Prioritizing quality improvement in pediatric cardiac surgery
Conclusions: A small number of procedures account for a substantial burden of morbidity, even among low mortality risk groups. Consideration should be given to using such objective prioritization schemes to develop targeted quality-improvement measures.
Source: The Journal of Thoracic and Cardiovascular Surgery - February 15, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Pirooz Eghtesady, Anoop K. Brar, Matthew Hall Tags: Congenital Heart Disease Source Type: research

Russian meteorite highlights asteroid danger
Friday's Russian meteorite strike highlights the need for a global strategy to deal with dangerous asteroidsIn terms of human casualties, Friday's meteorite strike is the worst ever reported. Almost 1,000 are reported to have sought treatment after the fall. At least 34 of them were hospitalised, with two reported to be in intensive care.Before this there were only stories of a dog being killed in Egypt by a meteorite in 1911 and a boy being hit, but not seriously injured, by one in Uganda in 1992.The Russian Academy of Sciences estimate the fireball that streaked over the Ural mountains on Friday morning weighed about 10 ...
Source: Guardian Unlimited Science - February 15, 2013 Category: Science Authors: Stuart Clark Tags: Blogposts Russia Astronomy News guardian.co.uk Meteors Science Source Type: news

On the well‐being of adult expremies in Denmark
ConclusionModerately premature infants, born before the era of intensive care, at the age of 32 years with regard to health, quality of life, education and social status proved to fare as well as their term counterparts.©2013 The Author(s)/Acta Pædiatrica ©2013 Foundation Acta Pædiatrica
Source: Acta Paediatrica - February 15, 2013 Category: Pediatrics Authors: Marianne Ulrich, Erik Lykke Mortensen, Claus Jensen, Jens Kamper Tags: Regular Article Source Type: research

Preface
Diabetes mellitus affects 8.3% of the US population. People with diabetes are twice as likely to be hospitalized, and their length of stay is approximately 30% longer compared to patients without diabetes. The management of blood glucose and the complications of hyperglycemia in the hospitalized patient with and without diabetes are the subject of many research studies. This issue covers the current guidelines for management of diabetes and hyperglycemia in the hospitalized patient. The issue begins with a review of the general recommendations for hospitalized patients with diabetes and hyperglycemia by Crawford. Brady the...
Source: Critical Care Nursing Clinics of North America - February 15, 2013 Category: Nursing Authors: Celia M. Levesque Source Type: research

Reporting Biases for Hospital-acquired Infections
I applaud Montecalvo et al for their study reporting a decrease in central venous catheter-associated bloodstream infections with the introduction of chlorhexidine baths in the intensive care units of a tertiary care and 4 community hospitals and sustaining lower infection rates when the study ended and chlorhexidine bathing continued.
Source: The American Journal of Medicine - February 15, 2013 Category: Journals (General) Authors: Harold Horowitz Tags: Letters Source Type: research

[Correspondence] Smartphones improve communication with parents in NICU
Parents of babies in the neonatal intensive-care unit (NICU) often find it difficult to understand and remember information relating to their sick babies. We have previously used an audio tape recorder to record, with their permission, parents' conversations with neonatologists and have then issued the parents with the audiocassettes to play back and listen to at their leisure. Our group has shown that audiotaping of neonatologist–parent conversations can help parents in the NICU. We have now found that smartphones could be even more useful.
Source: LANCET - February 15, 2013 Category: Journals (General) Authors: Tieh Hee Hai Guan Koh Tags: Correspondence Source Type: research

[Dealing with massive bleeding and associated perioperative coagulopathy : Recommendations for action of the German Society of Anaesthesiology and Intensive Care Medicine.]
[Dealing with massive bleeding and associated perioperative coagulopathy : Recommendations for action of the German Society of Anaesthesiology and Intensive Care Medicine.] Anaesthesist. 2013 Feb 15; Authors: Grottke O, Frietsch T, Maas M, Lier H, Rossaint R Abstract Massive bleeding with coagulopathy and hemorrhagic shock poses a potential threat to life in numerous clinical settings. Optimal treatment including the prevention of exsanguination necessitates a standardized and interdisciplinary approach. Several studies have shown the importance of massive transfusion protocols and standardized coagulation ...
Source: Der Anaesthesist - February 15, 2013 Category: Anesthesiology Authors: Grottke O, Frietsch T, Maas M, Lier H, Rossaint R Tags: Anaesthesist Source Type: research

Prompt administration of antibiotics is associated with improved outcomes in febrile neutropenia in children with cancer
ConclusionsTTA and presentation to the ED are independently associated with poor outcomes of FN. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - February 15, 2013 Category: Cancer & Oncology Authors: Matthew Fletcher, Hailey Hodgkiss, Song Zhang, Rachel Browning, Colleen Hadden, Tanja Hoffman, Naomi Winick, Timothy L. McCavit Tags: Research Article Source Type: research

Gender differences in referral pathways and admissions to a psychiatric intensive care unit in a county psychiatric hospital in the UK
Source: International Journal of Social Psychiatry - February 15, 2013 Category: Psychiatry Authors: Mustafa, F. A., Bayatti, Z., Faruqui, R. A. Tags: Articles Source Type: research

Acute haemodynamic effects of inhaled nitric oxide in premature infants with mild-to-moderate respiratory distress
Inhaled nitric oxide (iNO) selectively reduces pulmonary vascular resistance and pulmonary arterial pressure without affecting systemic arterial pressure.1 Premature infants with respiratory distress syndrome (RDS) may have elevated pulmonary vascular resistance, which may negatively affect the afterload-sensitive premature right ventricle, diminishing cardiac output. To date, no large study has been performed evaluating the acute haemodynamic effects of iNO in premature infants. This is a prospective observational study on 39 infants in our neonatal intensive care unit investigating the effects of early iNO in premature i...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Authors: Rhee, C. J., Sriram, S., Ionchev, A., Schreiber, M. D., Meadow, W. Tags: PostScript Source Type: research

Surgical retrieval of transected umbilical catheter from preterm infant
We present a 26 weeks gestation boy with a complication of central venous catheterisation. He was intubated in delivery suite, and admitted for intensive care. An umbilical venous catheter (UVC) was placed and used; however, there was difficulty obtaining umbilical arterial catheterisation (UAC) access due to thin cord. During subsequent attempts to place a UAC, the UVC was transected. It migrated inwards and could not be retrieved. The baby was transferred for on-going care, radiology and surgical management. Radiographs confirmed 6cm of catheter from umbilical vein to right atrium (figures 1 and 2). This did not cau...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Authors: Smith, J.-P., Cusick, E. L., Johnson, N., Mackenzie, S., Harding, D. Tags: Journalology, Child health, Infant health, Neonatal and paediatric intensive care, Neonatal health, Radiology, Neonatal intensive care, Clinical diagnostic tests, Radiology (diagnostics), Competing interests (ethics) Images in neonatal medicine Source Type: research

Respiratory distress in a preterm baby
Discussions with cardiologists, cardiothoracic surgeons and anaesthetists decided risk of tracheal surgery too high and the patient too small to cannulate for extracorporeal support. Parents understood futility of the situation and intensive therapy was stopped. Postmortem examination reported perforation of the right main bronchus. Tracheal perforation is a known but rare...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Authors: Turcu, S., Mok, Q. Tags: Oncology, Surgery, Journalology, Epidemiologic studies, Echocardiography, Hypertension, Pregnancy, Child health, Neonatal and paediatric intensive care, Neonatal health, Radiology, Surgical diagnostic tests, Clinical diagnostic tests, Radiology (diagnosti Source Type: research

Validation of the continuous glucose monitoring sensor in preterm infants
Conclusions CGMS can provide information on trends in glucose control, and guidance on the need for blood glucose assessment. This highlights the potential use of CGMS in optimising glucose control in preterm infants.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Authors: Beardsall, K., Vanhaesebrouck, S., Ogilvy-Stuart, A. L., Vanhole, C., vanWeissenbruch, M., Midgley, P., Thio, M., Cornette, L., Ossuetta, I., Palmer, C. R., Iglesias, I., de Jong, M., Gill, B., de Zegher, F., Dunger, D. B. Tags: Clinical trials (epidemiology), Child health, Infant health, Neonatal and paediatric intensive care, Neonatal health, Diabetes, Metabolic disorders Original articles Source Type: research

Positioning of infants in the neonatal intensive care unit for lumbar puncture as determined by bedside ultrasonography
Realising the paucity of data in the standardisation of the optimal position for lumbar puncture (LP) in hospitalised neonates, we have designed an observational study to measure the interspinous distance in infants in a university hospital setting. The infants were placed in two lateral recumbent and two upright positions (lateral recumbent without flexing the hips, lateral recumbent with maximal hip flexion, sitting without flexing the hips and sitting with maximal hip flexion) with concomitant heart rate (HR), transcutaneous oxygen saturation (OS) and interspinous distance (with ultrasonography) measurements. Having the...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Authors: Oncel, S., Gunlemez, A., Anik, Y., Alvur, M. Tags: Child health, Neonatal and paediatric intensive care, Neonatal health, Radiology, Neonatal intensive care, Clinical diagnostic tests, Radiology (diagnostics) Original articles Source Type: research

High variability and low irradiance of phototherapy devices in Dutch NICUs
Conclusions PT devices in the Dutch NICUs show considerable variability with often too low irradiance levels. These results indicate that suboptimal PT is frequently applied and may even be ineffective towards reducing total serum bilirubin levels. These results underline the need for greater awareness among all healthcare workers towards the requirements for effective PT including measurements of irradiance and distance.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Authors: van Imhoff, D. E., Hulzebos, C. V., van der Heide, M., van den Belt, V. W., Vreman, H. J., Dijk, P. H., the BARTrial Study Group, van Toledo-Eppinga, Mulder, Govaert, van Lingen, Lopriore, Buijs, van Imhoff, Dijk, Hulzebos, Liem, Benders, Fetter Tags: Child health, Neonatal and paediatric intensive care, Neonatal health, Physiotherapy, Neonatal intensive care Original articles Source Type: research

Benchmarking in neonatal intensive care: obstetrical and neonatal practices and registration policies may influence outcome data
Many regional, national or international neonatal networks, such as the Vermont Oxford Network or the EuroNeoNet, collect data on the outcome of very low birth weight infants (VLBWI) for benchmarking in order to improve quality of care. Whereas physicians use these data to assure quality of the outcomes of interest and to target interventions and new treatments, data collected on a national level may be used by political or healthcare organisations to reorganise their healthcare system. Furthermore, pregnant mothers with threatened preterm delivery may use data from individual units to decide at which perinatal centre they...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 15, 2013 Category: Perinatology & Neonatology Authors: Hummler, H. Tags: Epidemiologic studies, Pregnancy, Reproductive medicine, Child health, Infant health, Neonatal and paediatric intensive care, Neonatal health, Neonatal intensive care, Quality improvement Editorials Source Type: research

Iron autointoxication in a 16-year-old girl: a protective role for hepcidin?
We present a case of iron overdose in a 16-year-old girl who was found unconscious in her bed and brought to our emergency department. The most remarkable diagnostic findings were the patient's comatose condition, divergent eye position and positive Babinski foot pad reflexes. Laboratory tests showed hyperglycaemia and mild metabolic acidosis. A computed tomography scan of the cerebrum showed no signs of intracerebral haemorrhage or elevated intracerebral pressure. Toxicology screening showed no use of acetaminophen, ethanol or drugs of abuse. The patient was stabilized and monitored on the intensive care ward. When she wo...
Source: Annals of Clinical Biochemistry - February 15, 2013 Category: Biochemistry Authors: Simonse, E., Valk-Swinkels, C. G. H., van 't Veer, N. E., Ermens, A. A. M., Veldkamp, E. J. M. Tags: Case Reports Source Type: research

Most At-Risk ICU Patients Receiving Inadequate NutritionMost At-Risk ICU Patients Receiving Inadequate Nutrition
ICU patients at risk for harm if they fail to receive proper nutrition are often not being adequately fed, Canadian researchers reported at Clinical Nutrition Week 2013 in Phoenix, Arizona. Reuters Health Information
Source: Medscape Critical Care Headlines - February 14, 2013 Category: Intensive Care Tags: Critical Care News Source Type: news

Therapeutic hypothermia in term infants after perinatal encephalopathy: The last 5years in Switzerland
Conclusion: Target temperature can be achieved with all three cooling methods. Passive cooling has the highest variation of temperature. Neuromonitoring should be improved in Swiss neonatal and paediatric intensive care units. Our results stress the importance of national registries.
Source: Early Human Development - February 14, 2013 Category: Perinatology & Neonatology Authors: G. Ramos, B. Brotschi, B. Latal, V. Bernet, B. Wagner, C. Hagmann, the Swiss Neonatal Network Source Type: research

Necrotizing Enterocolitis: Hope on the Horizon
At long last, we are finally making progress in our understanding of necrotizing enterocolitis (NEC). As the readership of this periodical is well aware, despite all the successes of neonatal intensive care, the mortality and morbidity of NEC have remained largely unchanged. However, the past decade has seen new ground being broken in all areas of NEC research, including early diagnosis, medical and surgical management of acute NEC, and rehabilitation of those with a complicated disease course.
Source: Clinics in Perinatology - February 14, 2013 Category: Perinatology & Neonatology Authors: Patricia Wei Denning, Akhil Maheshwari Source Type: research

Arterial Tortuosity Syndrome: Early Diagnosis and Association With Venous Tortuosity
A newborn, first child of consanguineous parents was admitted to intensive care because of persistent pulmonary hypertension. The diagnosis of arterial tortuosity syndrome (ATS) was suspected due to severe tortuosity of the aorta (A) and pulmonary arteries (B and C, Online Video 1). Despite initial hospitalization, the first months of life were uneventful. He progressively developed peripheral pulmonary stenosis and moderate coarctation of the aorta. His facial features were characteristic (D), with elongated face, hypertelorism, and a long philtrum. He also presented with bilateral inguinal hernia, typical of connective t...
Source: Journal of the American College of Cardiology - February 14, 2013 Category: Cardiology Authors: Pamela Moceri, Juliette Albuisson, Marie Saint-Faust, Florence Casagrande, Fabienne Giuliano, Caroline Devos, Philippe Benoit, Nicolas Hugues, Dorothée Ducreux, Pierre Cerboni, Christian Dageville, Xavier Jeunemaitre Tags: IMAGES IN CARDIOLOGY Source Type: research

Am J Respir Crit Care Med; +47 new citations
47 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Respir Crit Care Med These pubmed results were generated on 2013/02/14PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources.
Source: Am J Respir Crit Car... - February 14, 2013 Category: Intensive Care Tags: Report Source Type: research

Good Posture Is Important But It Won’t Prevent Scoliosis
Remember when your parents told you to sit up straight? Slouching among adolescents hasn’t gone out of style and neither has the popular refrain. Sitting and standing tall remains important because it lengthens the spine, and strengthens the back, neck and shoulder muscles. But can good posture prevent the curving of the spine known as scoliosis? Unfortunately, it won’t, says Robert Lark, MD, a pediatric orthopedic surgeon with Duke Orthopaedics. “Scoliosis is not preventable,” he says, “but once we diagnose it, there are things we can do to prevent progression of the curve.” Scoliosis is an abnormal, left-to-r...
Source: DukeHealth.org: Duke Health Features - February 14, 2013 Category: Pediatrics Tags: Orthopaedics Source Type: news

Intermittent Pneumatic Compression and Not Graduated Compression Stockings Are Associated with Lower Incident Venous Thromboembolism in Critically Ill Patients: A Multiple Propensity Scores Adjusted Analysis.
CONCLUSIONS: The use of IPC, but not GCS was associated with a significantly lower VTE risk. This association was consistent regardless of the type of prophylactic heparin used and was not modified by the presence of trauma or being a surgical admission. PMID: 23412593 [PubMed - as supplied by publisher]
Source: Chest - February 14, 2013 Category: Respiratory Medicine Authors: Arabi YM, Khedr M, Dara SI, Dhar GS, Bhat SA, Tamim HM, Afesh LY Tags: Chest Source Type: research

Intensive care nurses' perception of futility: Job satisfaction and burnout dimensions.
This study was carried out to investigate the levels of job satisfaction and exhaustion suffered by intensive care nurses and the relationship between them through the futility dimension of the issue. The study included 138 intensive care nurses. The data were obtained with the futility questionnaire developed by the researchers, Maslach Burnout Inventory and Minnesota Satisfaction Questionnaire. It was determined that nurses who agreed to the proposition that the application of futility demoralizes health-care professionals had low levels of job satisfaction but high levels of depersonalization. It was determined that nur...
Source: Nursing Ethics - February 14, 2013 Category: Nursing Authors: Ozden D, Karagözoglu S, Yildirim G Tags: Nurs Ethics Source Type: research

Increased Risk of Intensive Care Unit Admission in Multiple Sclerosis (P03.205)
CONCLUSIONS: The risk of ICU admission is relatively high among persons with MS, particularly in younger MS patients. Given the recognized adverse consequences of critical illness in the general population, future studies should determine if there are modifiable risk factors for ICU admission.Supported by: The Manitoba Health Research Council and HSC Research Foundation.Disclosure: Dr. Marrie has received research support from Sanofi-aventis. Dr. Bernstein has received personal compensation for activities with Abbott, Janssen, Vertex Pharmaceuticals, Bristol-Myers Squibb Company, Mylan Pharmaceuticals, Ranbaxy Pharmaceutic...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Marrie, R.-A., Bernstein, C., Peschken, C., Hitchon, C., Fransoo, R., Garland, A. Tags: P03 Multiple Sclerosis: Cost and Impact of MS Care Source Type: research

Acute Encephalitis in the ICU: Predictors of Poor Outcome (P03.148)
CONCLUSIONS: Our study shows that in severe acute encephalitis predictors of poor outcome and death include potentially reversible conditions such as cerebral edema, status epilepticus and thrombocytopenia. These findings suggest that prevention, early detection and aggressive management of these factors in the ICU may modify outcome.Disclosure: Dr. Thakur has nothing to disclose. Dr. Motta has nothing to disclose. Dr. Asemoto has nothing to disclose. Dr. Benavides has nothing to disclose. Dr. McArthur holds stock and/or stock options in Gliamed. Dr. McArthur has received research support from Biogen Idec and Pfizer. Dr. G...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Thakur, K., Motta, M., Asemoto, A., Benavides, D., McArthur, J., Geocadin, R., Venkatesan, A. Tags: P03 Neurocritical Care: Epidemiology Source Type: research

Variants, Clinical Characteristics and Prognostic Factors of Guillain Barre Syndrome in Chinese (P01.135)
CONCLUSIONS: Miller Fisher syndrome is more common in the Chinese population compared to the West. Necessity of mechanical ventilation during hospitalization is an independent predictor of poor functional recovery and the Erasmus GBS Outcome Score is a useful score in predicting functional recovery.Disclosure: Dr. Kwok has nothing to disclose. Dr. Tsui has nothing to disclose. Dr. Wong has nothing to disclose. Dr. Wong has nothing to disclose. Dr. Chang has nothing to disclose. Dr. Hon has nothing to disclose. Dr. Mak has nothing to disclose. Dr. Cheung has nothing to disclose. Dr. Ho has nothing to disclose. Dr. Chan has ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kwok, K., Tsui, K., Wong, D., Wong, Y. K., Chang, R., Hon, S., Mak, W., Cheung, R., Ho, S. L., Chan, K. H., Lau, G. Tags: P01 Peripheral Nerve: Acute Inflammatory and Nutritional Source Type: research

Unexpected Burst-Suppression during Sedation with Anesthetic Agents in the ICU (P01.027)
CONCLUSIONS: Two-thirds of ICU patients receiving anesthetic agents for sedation who underwent EEG monitoring were found to be in burst-suppression, indicative of profound brain inactivation and over-sedation. This finding highlights the difficulty of consistently achieving target sedation levels in routine clinical practice. Improved monitoring and management strategies are needed to avoid the adverse effects of sedative overdosing.Disclosure: Dr. Pati has nothing to disclose. Dr. Rosenthal has nothing to disclose. Dr. Cash has nothing to disclose. Dr. Hochberg has nothing to disclose. Dr. Brown has nothing to disclose. D...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Pati, S., Rosenthal, E., Cash, S., Hochberg, L., Brown, E., Westover, M. Tags: P01 Neurocritical Care: Clinical Neurophysiology/Therapeutics Source Type: research

Melatonin, Light & Noise Reduction To Improve Sleep in the Neurological Intensive Care Unit (P01.025)
CONCLUSIONS: Sleep in many neurological ICU patients cannot be scored using standard methods. Those who could be scored had fragmented sleep with loss of restorative sleep stages. Larger patient sample size or alternative methods of scoring sleep are needed to better evaluate the use of sleep interventions in brain injured patients.Supported by: A 2011-2012 Pfizer Fellowships in Epilepsy from Pfizer's Medical and Academic Partnerships program.Disclosure: Dr. Foreman has received research support from Pfizer's Medical and Academic Partnerships program. Dr. Claassen has nothing to disclose. Dr. Bazil has received personal co...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Foreman, B., Claassen, J., Bazil, C. Tags: P01 Neurocritical Care: Clinical Neurophysiology/Therapeutics Source Type: research

Clinical pharmacy interventions in paediatric electronic prescriptions
Conclusions Paediatric prescribing errors occur frequently and are not completely prevented by electronic prescribing systems. This study provides information for improvements in electronic prescribing for paediatric patients. Incorporating tailored solutions, such as minimised free-text entry, certain obligatory fields and integrated dose checking and indications, can improve the quality and efficiency of electronic prescribing in paediatrics.
Source: Archives of Disease in Childhood - February 14, 2013 Category: Pediatrics Authors: Maat, B., Au, Y. S., Bollen, C. W., van Vught, A. J., Egberts, T. C. G., Rademaker, C. M. A. Tags: Health informatics, Epidemiologic studies, ADC Paediatric and Perinatal Drug Therapy, Drugs: infectious diseases, Child health, Medicines regulation, Adult intensive care Source Type: research

Use of online blood volume and blood temperature monitoring during haemodialysis in critically ill patients with acute kidney injury: a single-centre randomized controlled trial
Conclusions These results suggest that both actively controlled body temperature and UF profiled by online monitoring systems have no significant impact on the incidence of intradialytic hypotension in the ICU setting. Further research is needed before the use of these new sophisticated automatic methods can be applied routinely to the ICU setting.
Source: Nephrology Dialysis Transplantation - February 14, 2013 Category: Transplant Surgery Authors: du Cheyron, D., Terzi, N., Seguin, A., Valette, X., Prevost, F., Ramakers, M., Daubin, C., Charbonneau, P., Parienti, J.-J. Tags: Intra- and Extracorporeal Treatments of Kidney Failure Source Type: research

Parental presence and holding in the neonatal intensive care unit and associations with early neurobehavior
& R G Pineda
Source: Journal of Perinatology - February 14, 2013 Category: Perinatology & Neonatology Authors: L C ReynoldsM M DuncanG C SmithA MathurJ NeilT InderR G Pineda Tags: parenting holding visitation premature infant NICU Network Neurobehavioral Scale skin-to-skin Source Type: research

Coronavirus Person To Person Transmission Occurring In UK
A newly confirmed coronavirus infection in the UK indicates that it occurred as a result of person-to-person infection - the individual has no history of recent travel anywhere and no short- or long-term history of travel to the Middle East, the Health Protection Agency (HPA), UK, announced today. This latest case, involving a UK resident, brings the total number of confirmed coronavirus infection cases worldwide to 11 - three of them in the United Kingdom. Patient number 11 is currently receiving intensive care treatment at The Queen Elizabeth Hospital, Birmingham...
Source: Health News from Medical News Today - February 13, 2013 Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

Study Reveals Effects Of Meningitis And Septicaemia On Learning In School Children
A Meningitis Research Foundation funded study has shown that meningitis and septicaemia have a significant impact on children's school performance. Their ability to learn and their behaviour are especially affected and are worse than for children treated in intensive care with other critical illnesses. The new research, from Imperial College London, conducted at St Mary's and Great Ormond Street hospitals and just published in the journal Critical Care Medicine, looked at children aged 5 to 16 years old who had been in paediatric intensive care...
Source: Health News from Medical News Today - February 13, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news

Further UK case of novel coronavirus
The Health Protection Agency (HPA) can confirm a further case of novel coronavirus infection in a family member of the case announced on Monday 11 February. The patient, who is a UK resident, does not have any recent travel history and is currently receiving intensive care treatment at The Queen Elizabeth Hospital, Birmingham. It is understood that this patient has an existing medical condition that may make them more susceptible to respiratory infections. This latest case brings the total number of confirmed cases globally to 11, of which three have been diagnosed in the UK.
Source: Health Protection Agency - February 13, 2013 Category: UK Health Source Type: news

Hysterectomy After Childbirth – Laura’s Story
My name is Laura Boot-Handford and I recently turned 30. I grew up in the beautiful town Lewes, East Sussex. I met my Husband there whilst at college. We both went to University in Leicester and settled in Northampton nearby once we had finished. We bought our first house and two cats. We got married and soon thought about starting a family of our own.I was 27 when we had our first son, Harry. I had a consultant led pregnancy as I have Addisons, although I rarely saw the consultant. I started to get high blood pressure and traces of protein in my urine which was indicating the onset of pre eclampsia so the registrar deci...
Source: The Hysterectomy Association - February 13, 2013 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Post Birth Your Stories childbirth postpartum haemorrhage Womb transplant Source Type: news

Nafamostat mesilate for anticoagulation in continuous renal replacement therapy.
Conclusions: Nafamostat mesilate anticoagulation was associated with prolonged filter survival compared with heparin. These data suggest that nafamostat mesilate is a good choice for anticoagulant with prolonged filter survival during CRRT in critically ill patients. PMID: 23404639 [PubMed - as supplied by publisher]
Source: The International Journal of Artificial Organs - February 13, 2013 Category: Transplant Surgery Authors: Hwang SD, Hyun YK, Moon SJ, Lee SC, Yoon SY Tags: Int J Artif Organs Source Type: research

Increased morbidity in overweight and obese liver transplant recipients: A single centre experience of 1325 patients from the United Kingdom
Conclusions:This is the largest and the only reported UK series on BMI and outcome following liver transplantation. Overweight and obese patients have significantly increased morbidity in terms of infective complications following liver transplantation, with consequent longer intensive care and hospital stay. © 2013 American Association for the Study of Liver Diseases
Source: Liver Transplantation - February 13, 2013 Category: Transplant Surgery Authors: Abdul R Hakeem, Andrew J Cockbain, Syed S Raza, Stephen G Pollard, Giles J Toogood, Magdy A Attia, Niaz Ahmad, Ernest L Hidalgo, K Raj Prasad, Krishna V Menon Tags: Original Articles Source Type: research

Are the public ready for organ donation after out of hospital cardiac arrest?
Conclusions (1) The majority of patients and their relatives are not averse to OD being discussed shortly after ED death. (2) Organ preservation procedures are acceptable to many. Prior discussion and prior organ donor registration may improve acceptability.
Source: Emergency Medicine Journal - February 13, 2013 Category: Emergency Medicine Authors: Bruce, C. M., Reed, M. J., MacDougall, M. Tags: Drugs: cardiovascular system, Ethics, Resuscitation Original article Source Type: research

The Impact of Meeting Donor Management Goals on the Development of Delayed Graft Function in Kidney Transplant Recipients
The objective of this study was to determine the impact of meeting DMGs on delayed graft function (DGF) in renal transplant recipients. All eight OPOs of the United Network for Organ Sharing Region 5 prospectively implemented nine DMGs in every donor after neurologic determination of death (DNDD). “DMGs met” was defined a priori as achieving any seven of the nine DMGs and this was recorded at the time of consent for donation to reflect donor hospital ICU management, 12–18 h later, and prior to organ recovery. Multivariable analyses were performed to identify independent predictors of DGF (dialysis in the first week a...
Source: American Journal of Transplantation - February 13, 2013 Category: Transplant Surgery Authors: D. J. Malinoski, M. S. Patel, O. Ahmed, M. C. Daly, S. Mooney, C. O. Graybill, C. E. Foster, A. Salim, Tags: Original Article Source Type: research

Extracorporeal membrane oxygenation (ECMO) in patients with H1N1 influenza infection: a systematic review and meta-analysis including 8 studies and 266 patients receiving ECMO
Conclusions: ECMO is feasible and effective in patients with ALI due to H1N1 infection. Despite this, prolonged support (>1 week) is required in most cases, and subjects with severe comorbidities or multiorgan failure remain at high risk of in-hospital death.
Source: Critical Care - February 13, 2013 Category: Intensive Care Authors: Alberto ZangrilloGiuseppe Biondi-ZoccaiGiovanni LandoniGiacomo FratiNicolo PatronitiAntonio PesentiFederico Pappalardo Source Type: research