Internal Medicine Research
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 15.
Efficient drug screening and gene correction for treating liver disease using patient‐specific stem cells
Conclusions: Our results demonstrated the feasibility of effective large‐scale drug screening using an iPSC‐based disease model and highly robust gene targeting in human iPSCs; both of which are critical for translating the iPSC technology into novel therapies for untreatable diseases. (HEPATOLOGY 2013.)
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Su Mi Choi, Yonghak Kim, Joong Sup Shim, Joon Tae Park, Rui‐Hong Wang, Steven D. Leach, Jun O. Liu, Chu‐Xia Deng, Zhaohui Ye, Yoon‐Young Jang Tags: Liver Injury/Regeneration Source Type: research
Methionine adenosyltransferase 2B‐GIT1 interplay activates MEK1‐ERK1/2 to induce growth in human liver and colon cancer
Conclusion: MAT2B and GIT1 form a scaffold, which recruits and activates MEK and ERK to promote growth and tumorigenesis. This novel MAT2B/GIT1 complex may provide a potential therapeutic gateway in human liver and colon cancer. (HEPATOLOGY 2013.)
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Hui Peng, Lily Dara, Tony W.H. Li, Yuhua Zheng, Heping Yang, Lauda Maria Tomasi, Ivan Tomasi, Pasquale Giordano, Jose M. Mato, Shelly C. Lu Tags: Hepatobiliary Malignancies Source Type: research
Decreased risk of liver cancer with thiazolidinediones therapy in patients with type 2 diabetes: Results from a meta‐analysis
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Feng Wang, Shu‐Zhi Zhao, Ming‐Yue Zhang, Yan‐Lei Ma, Peng Zhang, Huan‐Long Qin Tags: Correspondence Source Type: research
Plasma interferon‐gamma‐inducible protein‐10 (IP‐10) levels during acute hepatitis C virus infection
Conclusion: High IP‐10 levels at acute HCV detection were associated with failure to spontaneously clear HCV. Patients with acute HCV and high baseline IP‐10 levels, particularly >380 pg/mL, should be considered for early therapeutic intervention, and those with low levels should defer therapy for potential spontaneous clearance. (HEPATOLOGY 2013.)
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Jason Grebely, Jordan J. Feld, Tanya Applegate, Gail V. Matthews, Margaret Hellard, Alana Sherker, Kathy Petoumenos, Geng Zang, Ineke Shaw, Barbara Yeung, Jacob George, Suzy Teutsch, John M. Kaldor, Vera Cherepanov, Julie Bruneau, Naglaa H. Shoukry, Andre Tags: Viral Hepatitis Source Type: research
BTB/POZ domain‐containing protein 7: Epithelial‐mesenchymal transition promoter and prognostic biomarker of hepatocellular carcinoma
Conclusion: The present study identifies BTBD7 as a novel candidate prognostic factor and a potential therapeutic target of HCC. (HEPATOLOGY 2013.)
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Yi‐Ming Tao, Jin‐Lin Huang, Shan Zeng, Sai Zhang, Xue‐Gong Fan, Zhi‐Ming Wang, Hui‐Xiang Yang, Xiao‐Hua Yuan, Pu Wang, Fan Wu, Jia Luo, De‐Yu Zeng, Hong Shen Tags: Hepatobiliary Malignancies Source Type: research
Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy
Abstract
Hepatic encephalopathy (HE) is a frequent complication of liver cirrhosis and is seen as the clinical manifestation of a low grade cerebral edema associated with oxidative‐nitrosative stress. However, comprehensive data on HE‐associated molecular derangements in human brain are lacking. In the present study we used a whole human genome micro‐array approach for gene expression profiling in post mortem brain samples from cirrhotic patients with or without HE and non‐cirrhotic controls. Altered expression levels were found for a total of 1012 genes in liver cirrhotic patients without and with HE and HE‐char...
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Boris Görg, Hans Jürgen Bidmon, Dieter Häussinger Tags: Liver Failure, Cirrhosis and Portal Hypertension Source Type: research
Reply to correspondence (HEP‐12‐2165) to 11‐1058.R2
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Chia‐Hsuin Chang, Jou‐Wei Lin, Mei‐Shu Lai, Lee‐Ming Chuang Tags: Correspondence Source Type: research
Soluble receptor for advanced glycation end products and risk of liver cancer
Conclusion: Our results support the hypothesis that sRAGE is inversely associated with liver cancer. The findings need confirmation, particularly in populations that include women and non‐smokers. (HEPATOLOGY 2013.)
Source: Hepatology - January 16, 2013 Category: Internal Medicine Authors: Kristin A. Moy, Li Jiao, Neal D. Freedman, Stephanie J. Weinstein, Rashmi Sinha, Jarmo Virtamo, Demetrius Albanes, Rachael Z. Stolzenberg‐Solomon Tags: Hepatobiliary Malignancies Source Type: research
Low‐frequency enzyme replacement therapy in late‐onset pompe disease
Source: Muscle and Nerve - January 16, 2013 Category: Internal Medicine Authors: Dar‐Shong Lin, Ming‐Fu Chiang, Che‐Sheng Ho, Chung‐Der Hsiao, Chang‐Yi Lin, Nien‐Lu Wang, Chih‐Kuang Chuang, Yu‐Wen Huang, Po‐Chun Chang, Hsuan‐Liang Liu Tags: Letter to the Editor Source Type: research
Double‐seropositive myasthenia gravis
Source: Muscle and Nerve - January 16, 2013 Category: Internal Medicine Authors: Vasiliki Zouvelou, Stavroula Kyriazi, Michael Rentzos, Maria Belimezi, Maria‐Angeliki Micheli, Socrates J. Tzartos, Eleftherios Stamboulis Tags: Letter to the Editor Source Type: research
Safety of plasma exchange therapy in patients with myasthenia gravis
Conclusion: PLEX is safe, effective, and well tolerated in patients with MG. Our results do not raise concerns about the safety of PLEX in patients with moderate–severe MG. Muscle Nerve, 2012
Source: Muscle and Nerve - January 16, 2013 Category: Internal Medicine Authors: Hamid Ebadi, David Barth, Vera Bril Tags: Research Article Source Type: research
Association of medical student burnout with residency specialty choice
Conclusions Specialty choices regarding lifestyle controllability and income were associated with the amount and type of medical school burnout, as well as with lifestyle‐, prestige‐ and patient care‐related motivation. Given that burnout may influence specialty choice, particularly with regard to the primary care specialties, medical schools may consider the utility of burnout prevention strategies.
Source: Medical Education - January 16, 2013 Category: Universities & Medical Training Authors: Lindsey Enoch, John T Chibnall, Debra L Schindler, Stuart J Slavin Tags: student and specialty choice Source Type: research
Prognostic contributions of the underlying inflammatory disease and acute organ dysfunction in critically ill patients with systemic rheumatic diseases.
CONCLUSION: Patients with SRD are mostly admitted in the ICU with infection or SRD exacerbation, and can be treated with immunosuppressive therapy and life-sustaining interventions with acceptable 30-day mortality. Death is associated with both the severity of the acute medical condition and the characteristics of the underlying SRD.
PMID: 23332934 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Faguer S, Ciroldi M, Mariotte E, Galicier L, Rybojad M, Canet E, Bengoufa D, Schlemmer B, Azoulay E Tags: Eur J Intern Med Source Type: research
Accuracy of Electronically Reported "Meaningful Use" Clinical Quality Measures: A Cross-sectional Study.
CONCLUSION: Wide measure-by-measure variation in accuracy threatens the validity of electronic reporting. If variation is not addressed, financial incentives intended to reward high quality may not be given to the highest-quality providers.
PRIMARY FUNDING SOURCE: Agency for Healthcare Research and Quality.
PMID: 23318309 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Kern LM, Malhotra S, Barrón Y, Quaresimo J, Dhopeshwarkar R, Pichardo M, Edwards AM, Kaushal R Tags: Ann Intern Med Source Type: research
Economic savings versus health losses: the cost-effectiveness of generic antiretroviral therapy in the United States.
CONCLUSION: Compared with a slightly less effective generic-based regimen, the cost-effectiveness of first-line branded ART exceeds $100 000/QALY. Generic-based ART in the United States could yield substantial budgetary savings to HIV programs.
PRIMARY FUNDING SOURCE: National Institute of Allergy and Infectious Diseases.
PMID: 23318310 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Walensky RP, Sax PE, Nakamura YM, Weinstein MC, Pei PP, Freedberg KA, Paltiel AD, Schackman BR Tags: Ann Intern Med Source Type: research
Selective d-Dimer Testing for Diagnosis of a First Suspected Episode of Deep Venous Thrombosis: A Randomized Trial.
CONCLUSION: A selective d-dimer testing strategy seems as safe as and more efficient than having everyone undergo d-dimer testing when diagnosing a first episode of suspected DVT.
PRIMARY FUNDING SOURCE: Heart and Stroke Foundation of Ontario.
PMID: 23318311 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Linkins LA, Bates SM, Lang E, Kahn SR, Douketis JD, Julian J, Parpia S, Gross P, Weitz JI, Spencer FA, Lee AY, O'Donnell MJ, Crowther MA, Chan HH, Lim W, Schulman S, Ginsberg JS, Kearon C Tags: Ann Intern Med Source Type: research
Online professionalism investigations by state medical boards: first, do no harm.
Abstract
Despite recent guidelines promoting online professionalism, consequences for specific violations by physicians have not been explored. In this article, the authors gauged consensus among state medical boards in the United States (response rate, 71%) about the likelihood of investigations for violations of online professionalism by using 10 hypothetical vignettes. High consensus was defined as more than 75% of respondents indicating that investigation was "likely" or "very likely," moderate consensus as 50% to 75% indicating this, and low consensus as fewer than 50% indicating this.Four online vignettes dem...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Greysen SR, Johnson D, Kind T, Chretien KC, Gross CP, Young A, Chaudhry HJ Tags: Ann Intern Med Source Type: research
The journey to electronic performance measurement.
PMID: 23318313 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Burstin H Tags: Ann Intern Med Source Type: research
Generic Antiretrovirals and the Uncertain Future of HIV Care in the United States.
PMID: 23318314 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Sherer R Tags: Ann Intern Med Source Type: research
The cost of quality.
PMID: 23318315 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Glod SA Tags: Ann Intern Med Source Type: research
But, doctor.
PMID: 23318316 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Sodhi N Tags: Ann Intern Med Source Type: research
Effect of a pharmacist intervention.
PMID: 23318317 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Criddle DT Tags: Ann Intern Med Source Type: research
Urinary incontinence in young nulligravid women.
PMID: 23318320 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Falola M Tags: Ann Intern Med Source Type: research
Escitalopram for the Prevention of Peginterferon-α2a-Associated Depression.
PMID: 23318323 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Landman GW Tags: Ann Intern Med Source Type: research
Menopausal hormone therapy and primary prevention.
PMID: 23318325 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Schaer TM Tags: Ann Intern Med Source Type: research
Colonoscopy and polyp characteristics.
PMID: 23318327 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Feuerstein JD, Leffler DA Tags: Ann Intern Med Source Type: research
High-value, cost-conscious care.
PMID: 23318329 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Kisloff B Tags: Ann Intern Med Source Type: research
NSAIDs were associated with increased risk for mortality, regardless of time since first MI.
CONCLUSION In patients previously hospitalized with a first myocardial infarction, nonsteroidal antiinflammatory drugs were associated with increased risk for mortality, regardless of time since myocardial infarction.Risk for death associated with NSAID use vs noncurrent NSAID use after hospitalization for a first MI*NSAIDPatients prescribed NSAIDsAt 1 y after first MIAt > 5 y after first MIEvents/100 person-yHazard ratio† (95% CI)Events/100 person-yHazard ratio† (CI)All44%20 vs 121.59 (1.49 to 1.69)9.8 vs 6.31.63 (1.52 to 1.74)Ibuprofen27%17 vs 131.42 (1.29 to 1.57)8.8 vs 6.31.55 (1.41 to 1.71)Diclofenac15%25 ...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Belknap SM Tags: Ann Intern Med Source Type: research
Review: Case management reduces mortality and HF readmissions in patients with HF.
CONCLUSIONS In patients with previous heart failure admissions, clinical service interventions reduce mortality and HF readmissions more than usual care. Results were most robust for case management.Clinical service interventions vs usual care in patients with previous HF hospitalizations*InterventionsOutcomesNumber of trials (n)Weighted event ratesRRR (95% CI)NNT (CI)All typesAll-cause mortality24 (5671)17% vs 22%21% (7 to 32)20 (13 to 50)HF readmission12 (3135)25% vs 37%30% (17 to 41)9 (6 to 17)Case managementMortality at ≅ 12 mo11 (2801)18% vs 25%27% (7 to 43)15 (9 to 50)HF mortality3 (1423)14% vs 16%10% (-15 to 30)No...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Van Spall HG Tags: Ann Intern Med Source Type: research
Review: Interventions for patient transition from hospital to primary care may improve outcomes.
CONCLUSION Several interventions to improve the transition of patient care from hospital to primary care may have positive effects on various processes or patient outcomes.Interventions to improve patient transition from hospital to primary careOutcomesNumber of trialsNumber of trials showing significant positive effects*Information sharingCoordination of careCommunicationPatient status†196 of 1311 of 179 of 17Errors, near-misses, or adverse events‡82 of 71 of 32 of 6Hospital use§207 of 129 of 179 of 18*Out of the number of trials assessing the outcome. Interventions could include ≥ 1 component.†Quality of life, ...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Schectman JM Tags: Ann Intern Med Source Type: research
A 13-item score based on readily available risk factors predicted risk for 3-year mortality in heart failure.
CONCLUSION A 13-item integer score based on readily available risk factors predicted risk for 3-year mortality in patients with heart failure and reduced or preserved ejection fraction.Predicted and observed risk for mortality by risk group in patients with heart failure†Risk group‡Number of patientsPredicted mortality at 3 y§Observed mortality at 3 y (95% CI)§1808311%8.8% (8.2 to 9.6)2716619%18% (17 to 19)3828328%27% (26 to 28)4720639%43% (41 to 44)5498053%55% (53 to 57)6365471%72% (70 to 73)†CI defined in Glossary.‡Risk groups are based on the first 4 quintiles (groups 1 to 4) and top 2 deciles (groups 5 and 6)...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Chatterjee S Tags: Ann Intern Med Source Type: research
Review: General health checks in adults do not reduce all-cause, cardiovascular, or cancer mortality.
CONCLUSIONS General health checks do not reduce all-cause, cardiovascular, or cancer mortality in primary care and community populations. Limited data exist to evaluate their effects on other outcomes.General health checks vs no health checks in adults in primary care or community settings*Outcomes†Number of trials (n)Illustrative risks‡At 4 to 22 y of follow-upRRR (95% CI)NNT (CI)All-cause mortality9 (155 899)7.4% vs 7.5%1% (-3 to 5)Not significantRRI (CI)NNH (CI)Cardiovascular mortality8 (152 435)3.8% vs 3.7%3% (-9 to 17)Not significantCancer mortality8 (139 290)2.1% vs 2.1%1% (-8 to 12)Not significant*Abbreviatio...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Lim LS Tags: Ann Intern Med Source Type: research
Hypoglycemia was associated with increased mortality in ICU patients regardless of glucose control strategy.
CONCLUSIONS In critically ill adults, intensive glucose control increased moderate and severe hypoglycemia more than conventional control. Moderate and severe hypoglycemia were each associated with increased risk for mortality compared with no hypoglycemia, regardless of intensity of glucose control treatment.Association between hypoglycemia and mortality in critically ill adults‡ComparisonsEvent ratesHazard ratio (95% CI)§Moderate|| vs no hypoglycemia29% vs 24%1.41 (1.21 to 1.62)Severe¶ vs no hypoglycemia35% vs 24%2.10 (1.59 to 2.77)‡CI defined in Glossary.§Stratified by treatment (intensive vs conventional glucose...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Rice TW Tags: Ann Intern Med Source Type: research
A single screening for type 2 diabetes in high-risk adults did not reduce mortality over 10 years.
CONCLUSION A single screening for type 2 diabetes in high-risk persons did not reduce mortality over 10 years compared with no screening.Screening vs no screening for type 2 diabetes in high-risk persons‡OutcomesEvent rate/1000 patient-yAt a median 9.6 y of follow-upScreeningNo screeningRRI (95% CI)All-cause mortality10.59.896% (-10 to 24)Cardiovascular mortality3.303.252% (-25 to 37)Cancer mortality4.784.438% (-10 to 29)Diabetes-related mortality0.510.4226% (-25 to 110)‡Abbreviations defined in Glossary. RRI and CI calculated from event rates and hazard ratios (adjusted for clustering) in article.
PMID: 23318338 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Mahon J Tags: Ann Intern Med Source Type: research
Review: Intensive blood pressure control reduces stroke, but not mortality or MI, in type 2 diabetes.
CONCLUSION Intensive blood pressure control reduced stroke, but not myocardial infarction or mortality, compared with standard control in adults with type 2 diabetes.Intensive vs standard blood pressure (BP) targets in adults with type 2 diabetes*OutcomesNumber of trials (n)†Weighted event ratesMean follow-up 2 to 5 yIntensive BP targetStandard BP targetRRR (95% CI)NNT (CI)Mortality5 (6812)5.1%6.4%20% (-14 to 44)Not significantMyocardial infarction4 (6683)8.9%9.6%7% (-9 to 21)Not significantStroke4 (6683)1.9%3.1%39% (17 to 55)82 (58 to 188)*Abbreviations defined in Glossary. Weighted intensive BP target event rate, RRR, ...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Moist L Tags: Ann Intern Med Source Type: research
Physician-, biomarker-, and symptom-based adjustment of inhaled corticosteroids for asthma had similar effects.
CONCLUSION In adults with mild to moderate asthma, biomarker- or symptom-based adjustment of inhaled corticosteroid dose did not reduce treatment failure compared with physician assessment-based adjustment.Adjustment of ICS dose based on a biomarker (BBA) or symptoms (SBA) vs physician assessment (PABA) in adults with mild to moderate asthma†OutcomeBBASBAPABAAt 36 wkRRR (97.5% CI)NNT (CI)Treatment failure18%-21%13% (-57 to 52)Not significant-14%21%33% (-28 to 65)Not significant†ICS = inhaled corticosteroid; other abbreviations defined in Glossary. Event rates, RRR, and CI calculated from number of events and randomized...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Stanbrook MB Tags: Ann Intern Med Source Type: research
Ginkgo biloba extract did not reduce risk for Alzheimer disease in elderly patients with memory complaints.
CONCLUSION Ginkgo biloba extract did not reduce risk for Alzheimer disease in elderly patients who reported memory complaints to their primary care physicians.Ginkgo biloba extract vs placebo for incident Alzheimer disease in elderly patients with memory complaints†YearGinkgo biloba extractPlaceboRRR (95% CI)NNT10.7%1.0%28% (-61 to 68)Not significantRRI (CI)NNH21.7%1.0%65% (-19 to 236)Not significant†Abbreviations defined in Glossary. RRR, RRI, NNT, NNH, and CI calculated from placebo event rates and hazard ratios in article.
PMID: 23318341 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Hirsch C Tags: Ann Intern Med Source Type: research
Clinically indicated and routine replacement of peripheral IV catheters did not differ for phlebitis.
CONCLUSION Clinically indicated peripheral IV catheter replacement did not differ from routine replacement every 3 days for phlebitis in hospitalized patients.Clinically indicated vs routine removal of peripheral IV catheters in hospitalized patients†OutcomesEvent ratesDuring catheterization or within 48 h after IV removalClinically indicatedRoutineRRI (95% CI)NNH (CI)Phlebitis‡7.2%6.7%6% (-17 to 36)NS†NS = not significant; other abbreviations defined in Glossary. RRI and CI calculated from relative risk in article.‡≥ 2 of patient-reported pain or tenderness with severity ≥ 2 on a 10-point scale; erythema ext...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Maki DG Tags: Ann Intern Med Source Type: research
Intermittent and continuous androgen deprivation did not differ for mortality after radiotherapy for prostate cancer.
CONCLUSION In men with increasing prostate-specific antigen levels after definitive radiotherapy for localized prostate cancer, intermittent androgen-deprivation therapy did not differ from continuous androgen deprivation for all-cause or prostate cancer mortality.IAD vs CAD in men with increasing prostate-specific antigen levels after definitive radiotherapy for localized prostate cancer‡OutcomesIADCADAt a median 6.9 yRRI (95% CI)NNH (CI)All-cause mortality39%37%2% (-11 to 16)Not significantProstate cancer mortality§17%14%21% (-6 to 53)Not significant‡CAD = continuous androgen deprivation; IAD = intermittent androgen...
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Stockler MR Tags: Ann Intern Med Source Type: research
Dendritic cells limit fibro‐inflammatory injury in NASH
Conclusion: Our findings support a role for DC in modulating NASH. Targeting DC functional properties may hold promise for therapeutic intervention in NASH. (HEPATOLOGY 2013.)
Source: Hepatology - January 15, 2013 Category: Internal Medicine Authors: Justin R. Henning, Christopher S. Graffeo, Adeel Rehman, Nina C. Fallon, Constantinos P. Zambirinis, Atsuo Ochi, Rocky Barilla, Mohsin Jamal, Michael Deutsch, Stephanie Greco, Melvin Ego‐Osuala, Usama Bin Saeed, Raghavendra S. Rao, Sana Badar, Juan P. Q Tags: Steatohepatitis and Metabolic Liver Disease Source Type: research
Sustained hcv clearance and increased HBsAg seroclearance in patients with dual chronic hepatitis C and B during post‐treatment follow‐up
Conclusion: Peginterferon alfa‐2a and ribavirin therapy provides a good durability of HCV SVR and a high accumulative HBsAg seroclearance rate in patients dually infected with HCV and HBV. (HEPATOLOGY 2013.)
Source: Hepatology - January 15, 2013 Category: Internal Medicine Authors: Ming‐Lung Yu, Chuan‐Mo Lee, Chi‐Ling Chen, Wan‐Long Chuang, Sheng‐Nan Lu, Chen‐Hua Liu, Shun‐Sheng Wu, Li‐Ying Liao, Hsing‐Tao Kuo, You‐Chen Chao, Shui‐Yi Tung, Sien‐Sing Yang, Jia‐Horng Kao, Wei‐Wen Su, Chih‐Lin Lin, Hung‐ Tags: Viral Hepatitis Source Type: research

