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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

A multicentre weight loss study using a low-calorie diet over 8 weeks: regional differences in efficacy across eight European cities.
CONCLUSIONS: The LCD significantly improved anthropometric and body composition measurements in all cities participating in DiOGenes. TRIAL REGISTRATION: ClinicalTrials.gov NCT00390637. PMID: 23348658 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - February 2, 2013 Category: Journals (General) Authors: Papadaki A, Linardakis M, Plada M, Larsen TM, van Baak MA, Lindroos AK, Pfeiffer AF, Martinez JA, Handjieva-Darlenska T, Kunešová M, Holst C, Saris WH, Astrup A, Kafatos A, On Behalf Of Diogenes Project DI, Obesity And GE, Supported By The EU Tags: Swiss Med Wkly Source Type: research

13-year-old tuberous sclerosis patient with renal cell carcinoma associated with multiple renal angiomyolipomas developing multifocal micronodular pneumocyte hyperplasia
Conclusion: Here we report a diagnostically challenging case of a 13-year-old patient with tuberous sclerosis and angiomyolipomas of the kidney who developed an unclassified renal cell carcinoma as well as multifocal micronodular pneumocyte hyperplasia. (Source: BioMed Central)
Source: BioMed Central - February 4, 2013 Category: Journals (General) Authors: Carl Ludwig BehnesGunther SchützeChristoph EngelkeFelix BremmerBastian GunawanHeinz-Joachim RadzunStefan Schweyer Source Type: research

Physical therapy treatments for low back pain in children and adolescents: a meta-analysis
Conclusions: Of all the physical therapy treatments for LBP in children and adolescents, the combination of therapeutic physical conditioning and manual therapy is the most effective. The low number of studies and control groups, and the methodological limitations in this meta-analysis prevent us from drawing definitive conclusions in relation to the efficacy of physical therapy treatments in LBP. (Source: BioMed Central)
Source: BioMed Central - February 2, 2013 Category: Journals (General) Authors: Inmaculada Calvo-MuñozAntonia Gómez-ConesaJulio Sánchez-Meca Source Type: research

From "magic bullets" to specific cancer immunotherapy.
Abstract The immune system is able to specifically target antigen-expressing cancer cells. The promise of immunotherapy was to eliminate cancer cells without harming normal tissue and, therefore, with no or very few side effects. Immunotherapy approaches have, for several decades, been tested against several tumours, most often against malignant melanoma. However, although detectable immune responses have regularly been induced, the clinical outcome has often been disappointing. The development of molecular methods and an improved understanding of tumour immunosurveillance led to novel immunotherapy approaches in t...
Source: Swiss Medical Weekly - February 2, 2013 Category: Journals (General) Authors: Riether C, Schürch C, Ochsenbein A Tags: Swiss Med Wkly Source Type: research

[Public Health] WHO and the future of disease control programmes
Huge increases in funding for international health over the past two decades have led to a proliferation of donors, partnerships, and health organisations. Over the same period, the global burden of non-communicable diseases has increased absolutely and relative to communicable diseases. In this changing landscape, national programmes for the control of HIV/AIDS, tuberculosis, malaria, and neglected tropical diseases must be reinforced and adapted for three reasons: the global burden of these communicable diseases remains enormous, disease control programmes have an integral and supporting role in developing health systems...
Source: LANCET - February 1, 2013 Category: Journals (General) Authors: Christopher Dye, Thierry Mertens, Gottfried Hirnschall, Winnie Mpanju-Shumbusho, Robert D Newman, Mario C Raviglione, Lorenzo Savioli, Hiroki Nakatani Tags: Public Health Source Type: research

[Correspondence] Politics and cancer management: lessons from Greece
Health should be managed according to evidence-based medicine and the principles of health equity and sustainability. Human rights should be respected, especially those of vulnerable cancer patients. However, political initiatives can easily undermine the role of the doctor when there are limited resources. (Source: LANCET)
Source: LANCET - February 1, 2013 Category: Journals (General) Authors: Ioanna G Tsiligianni Tags: Correspondence Source Type: research

Seroprevalence of chlamydial infection in dairy cattle in Guangzhou, southern China
The objective of the present investigation was to examine the chlamydial seroprevalence in dairy cattle in Guangzhou, subtropical southern China by using an indirect hemagglutination assay (IHA). The overall seroprevalence of chlamydial infection in dairy cattle was 7.25% (29/400). Greater than or equal to eight-yr-old dairy cattle had the highest seroprevalence (10.34%), followed by those that were >= 6 years old or < 7 years old dairy cattle (10.20%), although there were no statistically significant differences among different groups (P > 0.05). Dairy cattle with 5 pregnancies had the highest seroprevalence (10.81%). The...
Source: BioMed Central - February 4, 2013 Category: Journals (General) Authors: Dong-Hui ZhouFu-Rong ZhaoHui-Yan XiaMin-Jun XuSi-Yang HuangHui-Qun SongXing-Quan Zhu Source Type: research

The effectiveness of medical assistant health coaching for low-income patients with uncontrolled diabetes, hypertension, and hyperlipidemia: protocol for a randomized controlled trial and baseline characteristics of the study population
This study will add to the evidence base by determining the effectiveness of health coaching by medical assistants on clinical outcomes and patient self-management, by assessing the impact of health coaching on the clinician experience, and by examining the costs and potential savings of health coaching. Methods: This randomized controlled trial will evaluate the effectiveness of clinic-based medical assistant health coaches to improve clinical outcomes and self-management skills among low-income patients with uncontrolled type 2 diabetes, hypertension, or hyperlipidemia. A total of 441 patients from two San Francisco prim...
Source: BioMed Central - February 23, 2013 Category: Journals (General) Authors: Rachel Willard-GraceDenise DeVoreEllen H ChenDanielle HesslerThomas BodenheimerDavid H Thom Source Type: research

[Articles] Cognitive behavioural therapy as an adjunct to pharmacotherapy for primary care based patients with treatment resistant depression: results of the CoBalT randomised controlled trial
Before this study, no evidence from large-scale randomised controlled trials was available for the effectiveness of augmentation of antidepressant medication with CBT as a next-step for patients whose depression has not responded to pharmacotherapy. Our study has provided robust evidence that CBT as an adjunct to usual care that includes antidepressants is an effective treatment, reducing depressive symptoms in this population. (Source: LANCET)
Source: LANCET - February 1, 2013 Category: Journals (General) Authors: Nicola Wiles, Laura Thomas, Anna Abel, Nicola Ridgway, Nicholas Turner, John Campbell, Anne Garland, Sandra Hollinghurst, Bill Jerrom, David Kessler, Willem Kuyken, Jill Morrison, Katrina Turner, Chris Williams, Tim Peters, Glyn Lewis Tags: Articles Source Type: research

Pulmonary perfusion with oxygenated blood or custodiol HTK solution during cardiac surgery for postoperative pulmonary function in COPD patients: a trial protocol for the randomized, clinical, parallel group, assessor and data analyst blinded Pulmonary Protection Trial
DiscussionPatients with COPD may be impaired by hypoxemia and SIRS. Thus, prolonged recovery and even postoperative complications and death may be reflected by the degree of hypoxemia and SIRS. The limited sample size does not aim for confirmatory conclusions on mortality, cardiovascular complications or risk of pneumonia and sepsis, but the PP-Trial is considered an important feasibility trial paving the road for a multicenter confirmatory trial.Trial registration: ClinicalTrials.gov: NCT01614951. (Source: Trials)
Source: Trials - January 31, 2013 Category: Journals (General) Authors: Katrine BuggeskovJørn WetterslevNiels SecherLars AndersenThomas JonassenDaniel Steinbrüchel Source Type: research

CA-125--indicated asymptomatic relapse confers survival benefit to ovarian cancer patients who underwent secondary cytoreduction surgery
Conclusions: The increase of serum CA-125 levels is an early warning of clinical relapse in ovarian cancer. Using CA-125 levels in guiding the treatment of patients with asymptomatic recurrent ovarian cancer, who have shown CCR to primary therapy, can facilitate optimal secondary CRS and extend the survival duration of the patients. (Source: BioMed Central)
Source: BioMed Central - February 12, 2013 Category: Journals (General) Authors: Fang WangYanfen YeXia XuXuehui ZhouJinhua WangXiaoxiang Chen Source Type: research

Cystatin C and neutrophil gelatinase-associated lipocalin: biomarkers for acute kidney injury after congenital heart surgery.
CONCLUSIONS: In patients after congenital heart surgery, urine NGAL indicates the damaging force of cardiopulmonary bypass and serum Cystatin C is a valuable predictive biomarker for resulting acute kidney injury. PMID: 23348800 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - February 2, 2013 Category: Journals (General) Authors: Seitz S, Rauh M, Gloeckler M, Cesnjevar R, Dittrich S, Koch AM Tags: Swiss Med Wkly Source Type: research

[Articles] Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial
Individually optimised energy supplementation with SPN starting 4 days after ICU admission could reduce nosocomial infections and should be considered as a strategy to improve clinical outcome in patients in the ICU for whom EN is insufficient. (Source: LANCET)
Source: LANCET - February 1, 2013 Category: Journals (General) Authors: Claudia Paula Heidegger, Mette M Berger, Séverine Graf, Walter Zingg, Patrice Darmon, Michael C Costanza, Ronan Thibault, Claude Pichard Tags: Articles Source Type: research

Protocol: optimising hydroponic growth systems for nutritional and physiological analysis of Arabidopsis thaliana and other plants
Conclusions: We present an optimised plant hydroponic culture system that can be quickly and cheaply constructed, and produces plants with similar growth kinetics to soil-grown plants, but with the advantage of being a versatile platform for a myriad of physiological and molecular biological measurements on all plant tissues at all developmental stages. We present 'tips and tricks' for the easy adoption of this hydroponic culture system. (Source: BioMed Central)
Source: BioMed Central - February 4, 2013 Category: Journals (General) Authors: Simon J ConnBradleigh HockingMaclin DayodBo XuAsmini AthmanSam HendersonLucy AukettVanessa ConnMonique K ShearerSigfredo FuentesStephen D TyermanMatthew Gilliham Source Type: research

Symptomatic gastroesophageal reflux amongst hospital personnel in South India
Conclusion: GER prevalence is not uncommon amongst the hospital personnel. It is significantly more common amongst doctors, clerical staff and housekeepers. (Source: Indian Journal of Medical Sciences)
Source: Indian Journal of Medical Sciences - February 27, 2013 Category: Journals (General) Authors: CM BhalaghuruS VijayaVenkataraman Jayanthi Source Type: research

Policy development, implementation and evaluation by the AIDS control program in Uganda: a review of the processes
Conclusions: Policy development and revision of the SMC and HCT policies followed similar processes. Gaps identified included lack of protocols/SOPs for the processes and limited indigenous funding to support adherence to anticipated timelines. We recommend active involvement of the policy analysis unit in all policy processes. Specific protocols/SOPs for development, analysis, revision, implementation, monitoring, evaluation and impact assessment processes should be developed prior to commencement of the activities. (Source: BioMed Central)
Source: BioMed Central - February 23, 2013 Category: Journals (General) Authors: Benson T TumwesigyeDamalie NakanjakoRhoda WanyenzeZainab AkolNelson Sewankambo Source Type: research

Long-term consistent use of a vaginal microbicide gel among HIV-1 sero-discordant couples in a phase III clinical trial (MDP 301) in rural south-west Uganda
Conclusion: In rural Uganda younger women and women in houses with less space are likely to require additional support to achieve consistent microbicide gel use.Trial registration: Protocol Number ISRCTN64716212 (Source: Trials)
Source: Trials - February 1, 2013 Category: Journals (General) Authors: Andrew AbaasaAngela CrookMitzy GafosZacchaeus AnywaineJonathan LevinSymon WandiembeAnanta NanooAndrew NunnSheena McCormackRichard HayesAnatoli Kamali Source Type: research

[Editorial] Suicide in the UK: questioning ourselves
Suicide rates touch the national psyche in a way that few other statistics can. While cancer mortality rates, for example, might make a society question the effectiveness of its health service, suicide rates make a society question itself. (Source: LANCET)
Source: LANCET - February 1, 2013 Category: Journals (General) Authors: The Lancet Tags: Editorial Source Type: research

[This Week in Medicine] February 2–8, 2013
An independent panel convened by the US National Institutes of Health has recommended a change of name and classification for polycystic ovary syndrome (PCOS). The current name focuses on ovarian cysts, yet the causes and complete phenotype are complex. Additionally, three different classification systems are used. The panel proposed use of the broad Rotterdam criteria. (Source: LANCET)
Source: LANCET - February 1, 2013 Category: Journals (General) Authors: The Lancet Tags: This Week in Medicine Source Type: research

Nitric Oxide Measure Lower in Younger Kids (CME/CE)
SAN ANTONIO (MedPage Today) -- Levels of fractional exhaled nitric oxide, a key measure of airway inflammation related to asthma, are substantially lower in younger children than older ones, a researcher said here. (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - February 27, 2013 Category: Journals (General) Source Type: news