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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 22.

Bioelectrical impedance and visceral fat: a comparison with computed tomography in adults and elderly
CONCLUSION: BIA was found to have satisfactory sensitivity and specificity to predict VF; however, other devices and other techniques should be investigated to improve VF prediction.
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - February 26, 2013 Category: Endocrinology Source Type: research

Cigarette smoke exposure severely reduces peripheral insulin sensitivity without changing GLUT4 expression in oxidative muscle of Wistar rats
CONCLUSION: These results suggest that passive smoking stimulates GLUT4 transcription without changing total protein content, but impairs the ability of GLUT4 translocation to the PM. On the other hand, training seems to reduce the deleterious effects, even under the influence of cigarette smoking.OBJETIVO: Avaliar o efeito da exposição à fumaça de cigarro e do treinamento de corrida em esteira rolante sobre a expressão do transportador de glicose GLUT4 no músculo oxidativo solear de ratos. MATERIAIS E MÉTODOS: Ratos Wistar foram divididos em: (C) controle, (E) exercitado, (SS) fumante sedentário e (ES) fumante exe...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - February 26, 2013 Category: Endocrinology Source Type: research

Implementation of a structured healthy lifestyle program to reduce cardiometabolic risk
This study may indicate ways for health professionals to tailor local care conditions and promote a healthy lifestyle, working with a new perspective.
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - February 26, 2013 Category: Endocrinology Source Type: research

Relationship between subclinical atherosclerosis, blood pressure, and lipid profile in obese children and adolescents: a systematic review
O estudo teve como objetivo revisar sistematicamente a literatura sobre espessamento médio-intimal (EMI), pressão arterial (PA) e perfil lipídico (PL) de crianças e adolescentes obesos e não obesos. A busca foi realizada em bases de dados eletrônicas (PubMed, Bireme e Elsevier ScienceDirect) entre 2000-2010. Os seguintes descritores, em inglês, foram usados: "obesity", "adolescents", "atherosclerosis" e "child", sendo utilizadas duas combinações: obesity+child+atherosclerosis e obesity+adolescents+atherosclerosis. A busca eletrônica inicial resultou em 3.211 artigos. Após a aplicação dos critérios de inclusã...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - February 26, 2013 Category: Endocrinology Source Type: research

Dietary Bioavailability of Cu Adsorbed to Colloidal Hydrous Ferric Oxide
Environmental Science & TechnologyDOI: 10.1021/es3044856
Source: Environmental Science and Technology - February 26, 2013 Category: Environmental Health Authors: Daniel J. Cain, Marie-Noële Croteau and Christopher C. Fuller Source Type: research

Femtosecond Spectroscopic Study of Photoinduced Charge Separation and Recombination in the Donor–Acceptor Co-Oligomers for Solar Cells
The Journal of Physical Chemistry CDOI: 10.1021/jp3106925
Source: The Journal of Physical Chemistry C - February 26, 2013 Category: Chemistry Authors: Bing-Rong Gao, Jian-Fei Qu, Yan Wang, Ying-Ying Fu, Lei Wang, Qi-Dai Chen, Hong-Bo Sun, Yan-Hou Geng, Hai-Yu Wang and Zhi-Yuan Xie Source Type: research

Omega‐3 polyunsaturated fatty acids reduce insulin resistance and triglycerides in obese children and adolescents
ConclusionThe results of this work suggest that ω‐3 may be useful as an adjuvant therapy in obese children and adolescents with IR.
Source: Pediatric Diabetes - February 26, 2013 Category: Endocrinology Authors: Carlos Juárez‐López, Miguel Klünder‐Klünder, Adrián Madrigal‐Azcárate, Samuel Flores‐Huerta Tags: Original Article Source Type: research

Potencies of Red Seabream AHR1- and AHR2-Mediated Transactivation by Dioxins: Implication of Both AHRs in Dioxin Toxicity
Environmental Science & TechnologyDOI: 10.1021/es304423w
Source: Environmental Science and Technology - February 26, 2013 Category: Environmental Health Authors: Su-Min Bak, Midori Iida, Masashi Hirano, Hisato Iwata and Eun-Young Kim Source Type: research

Protein Analysis by Shotgun/Bottom-up Proteomics
Chemical ReviewsDOI: 10.1021/cr3003533
Source: Chemical Reviews - February 26, 2013 Category: Chemistry Authors: Yaoyang Zhang, Bryan R. Fonslow, Bing Shan, Moon-Chang Baek and John R. Yates Source Type: research

Electrostatically Embedded Molecular Tailoring Approach and Validation for Peptides
Journal of Chemical Theory and ComputationDOI: 10.1021/ct300845q
Source: Journal of Chemical Theory and Computation - February 26, 2013 Category: Chemistry Authors: Miho Isegawa, Bo Wang and Donald G. Truhlar Source Type: research

Purinoceptor‐mediated, Capsaicin‐resistant Excitatory Effect of Allyl Isothiocyanate on Neurons of the Guinea‐Pig Small Intestine
Abstract Allyl isothiocyanate (AITC; 200 μM) caused atropine‐ and tetrodotoxin‐sensitive longitudinal muscle contraction on the guinea‐pig small intestine. The response was not influenced by hexamethonium, a functional blockade of capsaicin‐sensitive neurons or by antagonists acting at TRPV1 or TRPA1, but was abolished by the P2 purinoceptor antagonist PPADS (50 μM). It is concluded that cholinergic motoneurons are activated by a purinergic mechanism in the course of the AITC response, independently of capsaicin‐sensitive processes or even TRPA1.
Source: Basic and Clinical Pharmacology and Toxicology - February 26, 2013 Category: Drugs & Pharmacology Authors: Lorand Bartho, Elin Nordtveit, Veronika Szombati, Rita Benko Tags: Short Communication Source Type: research

Study of dissolution profiles and desintegration of capsules containing the dried hydroethanolic extract of Calophyllum brasiliense
Calophyllum brasiliense Cambess, Calophyllaceae, is of great interest in folk medicine and is used in the treatment of various diseases such as diabetes. Granules containing the hydroethanolic extract from the stem bark of C. brasiliense were obtained. The polyphenol content was standardized, and the average weight, disintegration, and the dissolution profiles of the capsules were determined after encapsulation. The capsules had an average weight of 574.5±8.0 mg. In vitro tests showed that the most efficient disintegration profile was in hydrochloric acid buffer (pH 1.2), with a capsule disintegration time within 9 min. T...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Development of tablets containing semipurified extract of guaraná (Paullinia cupana)
This study evaluated the technological feasibility of producing a semipurified extract of guaraná (Paullinia cupana Kunth, Sapindaceae) in tablet form, using a direct-compression process. Maltodextrin and gum arabic were used to produce the extract microparticles, in order to protect the microparticles against such factors as temperature, oxidation, and humidity. Using pharmacopoeial methodologies, technological and physicochemistry tests (determination of residual moisture, of bulk and tapped density, Hausner ratio, compressibility and compactibility index, appearance, mean weight, hardness, friability, disintegration ti...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Effect of rosemary (Rosmarinus officinalis) extract on the biodistribution of 99mTc sulphur colloid and on the radiolabeled blood constituents
With this study we evaluated the effects of the herb rosemary (Rosmarinus officinalis L. Lamiaceae) extract on the labeling of blood constituents with technetium-99m (99mTc) labeled sulphur colloid and on the biodistribution of 99mTc-Sulphur Colloid in Wistar albino rats. For this purpose, two groups of animals (male wistar rats, 130-140 g) were treated (1 mL) with a rosemary extract (750 mg/kg body wt.,n=9) and water (control, n=9) separately by gavage for five days. 99mTc-Sulphur Colloid was administrated by intravenous injection; organs/tissues were withdrawn and weighted. Blood was centrifuged, plasma and blood cells w...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Preparation and characterization of solid oral dosage forms containing soy isoflavones
Soy isoflavones have been extensively used for menopausal symptoms and prevention of hormone-related cancer, osteoporosis and cardiovascular diseases. Commercially available forms of isoflavones include supplements, capsules and tablets. However, the non-standardization of soy isoflavones extracts and different dissolution profiles of these solid dosage forms highlight the need of additional studies on the development of well characterized pharmaceutical dosage forms of isoflavones. In this work, immediate release oral tablets of soy isoflavones were obtained and evaluated. Genistein and daidzein, were the main constituent...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Preparation of pellets containing Pothomorphe umbellata extracts by extrusion-spheronization: improvement of 4-nerolidylcatechol photostability
Pothomorphe umbellata (L.) Miq., Piperaceae, has been extensively used in Brazilian folk medicine and it is well known for its strong antioxidant properties. However, its main active constituent, 4-nerolydilcatechol (4-NC), is sensitive to ultraviolet and visible light, which can limit the use of intermediate and final herbal preparations of this species. In the present work, coated multiparticulate solid dosage forms of P. umbellata were obtained with the purpose of increasing the stability of 4-NC. P. umbellata extract was used as a wetting liquid for the preparation of pellets by extrusion-spheronization. Pellets were c...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Technological development of Cecropia glaziovi extract pellets by extrusion-spheronization
In conclusion, pellets containing a high dose of the C. glaviovi extract were successfully prepared, achieving degrees of quality, physical stability and feasibility compatible with the desirable characteristics of a phytopharmaceutical.
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Development and characterization of PLGA nanocapsules of grandisin isolated from Virola surinamensis: in vitro release and cytotoxicity studies
The most studied phyto constituent isolated from Virola surinamensis (Rol. ex Rottb.) Warb., Myristicaceae, is the tetrahydrofuran neolignan grandisin, which exhibits a series of biological activities, including trypanocidal, larvicidal and antitumoral. Due to its extremely low solubility, additional studies, including in vivo investigations are challenged by the difficulties in the development of an effective drug delivery system for grandisin. The encapsulation in polymeric nanoparticles is a very attractive alternative for overcoming some of these limitations. In this work, PLGA nanocapsules loaded with grandisin were d...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
Aqueous extract from seeds of Syzygium cumini (L.) Skeels, Myrtaceae, obtained by dynamic maceration was spray-dried and characterized by its physico-chemical and antihyperglycaemic action. The extract showed to possess high amount of polyphenols, significant in vitro free radical scavenger activity using the DPPH method and an antihyperglycaemic effect in alloxan-induced experimental diabetes. S. cumini spray-dried extracts were obtained using silicon dioxide and cassava starch as adjuvants. The powders showed acceptable flowability, compactability, and low hygroscopicity at 43% relative humidity. Besides, the spray-dried...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Anti-inflammatory and antinociceptive activities of Phyllanthus niruri spray-dried standardized extract
In conclusion, this study suggested that Phyllanthus niruri spray-dried standardized extract has potent inflammatory and antinociceptive activities and that these activities are not modified by standard drying process, making it feasible to use the dry extract standardized to obtain a phytotherapic preparation and thus validating its use for the treatment of pain and inflammation disorders.
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Influence of process conditions on the physicochemical characteristics of cumaru (Amburana cearensis) powder produced by spray drying
The aim of the work was to study the spray-drying of ethanolic extract from Amburana cearensis (Allemão) A.C. Sm., Fabaceae, in order to obtain powders with better pharmacological and technological properties for herbal medicine. A 2³ fractional factorial statistical design was used to find adequate spray-drying operating conditions (inlet air temperature; feed flow rate and air flow rate) to produce A. cearensis powder with adequate concentration of active principles (amburoside and coumarin), low moisture content and high process yield. The HPLC analyses showed that the spray-drying powder of A. cearensis production di...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Anti-inflammatory, antiallodynic effects and quantitative analysis of gallic acid in spray dried powders from Phyllanthus niruri leaves, stems, roots and whole plant
In conclusion, differences in the chemical composition of spray dried powders from P. niruri are reflected in their in vivo pharmacological actions. Despite of a direct relationship of anti-inflammatory and antiallodynic effects with the gallic acid content had been observed, especially in the spray dried powders of leaves, the use of spray dried powders of leaves plus stems showed to be more effective, suggesting a synergic effect between their constituents.
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Spray drying of Eugenia dysenterica extract: effects of in-process parameters on product quality
A 2³ full factorial design was used to assess the impact of spraying air flow rate (30-50 L/min), drying air inlet temperature (90-150 ºC) and extract feed rate (4-6 g/min) on the quality of Eugenia dysenterica DC., Myrtaceae, spray-dried extracts. Response surface methodology (RSM) was applied to analyze the significance of the effects of process factors on product quality and to obtain fitted equations to predict dry powder properties. Powder yields were satisfactory, ranging from 34.64 to 63.92%. The dried products showed moisture contents and water activities below 5% and 0.5, respectively. The recuperation ratios of...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

HLB value, an important parameter for the development of essential oil phytopharmaceuticals
Essential oils are used primarily as natural preservatives, flavourants and fragrances in cosmetic products. Several pharmacopeias possess monographs of plants which are good sources of essential oils, such as Brazilian Pharmacopeia, including Illicium verum Hook. f., Schisandraceae and Rosmarinus offi cinalis. Since determination of Hydrophile-Lipophile Balance (HLB) value of essential oils appears as a critical step for development of emulsions and other semi-solid formulations, evaluation of required HLB values for I. verum and R. offi cinalis essential oils is the aim of this study. They were obtained by hydrodistillat...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Hydroalcoholic extracts of Vellozia squamata: study of its nanoemulsions for pharmaceutical or cosmetic applications
Some species of plants are notable for the wide range of biologically active constituents in their tissues. Chemical and pharmacological studies of Vellozia squamata Pohl, Velloziaceae, popularly known in Brasil as "canela-de-ema" are scarce, but showed the presence of di-and triterpenoid that may be of scientific interest. In the present study the hydroalcoholic extracts from leafs and stems of V. squamata were submitted to phytochemical prospection to identify the principal groups of constituents, and the antioxidant activity was determined by DPPH method. The hydroethanolic extracts presented higher antioxidant activity...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Optimization of the extraction of curcumin from Curcuma longa rhizomes
The aim of this work was to study the effect of dynamic maceration factors upon the curcumin content of Curcuma longa L., Zingiberaceae, extracts and to determine the optimum set of parameters for the extraction of curcumin using a 2(5) full factorial design and the response surface methodology. Under the established conditions, the content of soluble solids and curcumin in the extracts ranged from 0.8 to 3.4%, and from 0.1 to 1.8%, respectively. The most influential variable observed for the extraction was the ethanolic strength of the solvent. The optimized condition involves an extraction time of 12 h, agitation spe...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Soybean extracts enriched with free isoflavones promote nitric oxide synthesis and affect the proliferation of breast adenocarcinoma cells
Although soybean isoflavones naturally accumulate in their conjugated forms, the beneficial effects on human health of soybean-containing foods have been credited to their aglycone forms. In the present study we analyzed the effects of a chemical agent, sodium nitroprusside (SNP), in eliciting the exudation of non-conjugated isoflavones from intact soybean seeds, embrionary axes and cotyledons. The isoflavones in the exudates were determined by high performance liquid chromatography and mass spectrometry. The effect of the exudates on the emission of nitric oxide (NO) and on the proliferation of breast carcinoma cells (MCF...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Dynamic maceration of Copaifera langsdorffii leaves: a technological study using fractional factorial design
In conclusion, this study allowed visualizing which factors were considered the most important in copaiba leaves dynamic maceration and their effect in extract antioxidant activity. Furthermore, this technological study gives directions to optimize future extraction experiments from C. langsdorffii.
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Development of hydroethanolic extract of Ipomoea pes-caprae using factorial design followed by antinociceptive and anti-inflammatory evaluation
Ipomoea pes-caprae (L.) R. Br., Convolvulaceae, is a medicinal plant that grows abundantly as a pan-tropical stand plant. The 3² (two factors and three levels) factorial design, was applied to determine the best time and drug/solvent proportion to maximize the flavonoid content in the hydroethanolic extract by maceration process. The antinociceptive and anti-inflammatory effects were studied at 5-20 mg/kg, i.p., using the writhing test and carrageenan-induced pleurisy models in mice. The optimized extract was able to inhibit more than 50% of abdominal writhing at 20 mg/kg, with 55.88%±2.4 of maximum inhibition. Indometha...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Box-Behnken design to study the bergenin content and antioxidant activity of Endopleura uchi bark extracts obtained by dynamic maceration
The objective of this work was to study the Endopleura uchi barks extraction using the dynamic maceration method and the effects of the extraction time, drug to solvent ratio and temperature. A Box-Behnken design was applied to study the influence of these factors and the respective response surfaces. The extract characterization was made by determination of its antioxidant activity by DPPH; total polyphenol content and bergenin content. In general, the extracts showed good antioxidant activity, with the IC50 ranging from 4.02 to 5.87 µg/mL. The polyphenol content ranged from 31.89 to 47.82%. High levels of chemical marke...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Development and validation of a HPLC method for the quantification of three flavonoids in a crude extract of Dimorphandra gardneriana
In this study, an excellent linearity was obtained with r higher than 0.99. Besides, the chromatographic peaks showed good resolution. With other validation data, including precision, specificity, accuracy and robustness, this method demonstrated good reliability and sensitivity, and can be conveniently used for the quantification of rutin, isoquercitrin and quercetin in crude methanolic extract of D. gardneriana pods. Furthermore, there are the advantages of easy sample preparation and short time between each injection.
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Comparative evaluation of UV/VIS and HPLC analytical methodologies applied for quantification of flavonoids from leaves of Bauhinia forficata
Spectrophotometric determinations (direct dilution or after acid hydrolysis) of flavonoid content in leaves of Bauhinia forficata Link, Fabaceae, from two different regions from Brazil were compared with contents of kaempferitrin quantified by HPLC analysis. The absence of kaempferitrin peak in one sample denotes the risk of LC-method failure. On the other hand, the both spectrophotometric assays showed satisfactory performance and do not underwent influence from absence of kaempferitrin. Since several flavonoids are present in the herbal material, different content of flavonoids were observed for each analytical procedure...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Variation in phenolic compounds of Ugni molinae populations and their potential use as antioxidant supplement
In the present work we carried out a comparative study of total phenolic contents and antioxidant capacity of aqueous leaf extracts of Ugni molinae Turcz., Myrtaceae (infusion and Soxhlet extracted) prepared from continent and Juan Fernández Island samples. The results revealed that total phenol content (TPC), tannins (TTC) and flavonoids (TFC) for U. molinae extracts (infusion and Soxhlet extracts) from island leaves were 38.5, 56.7 and 37.5% higher than those obtained with leaves from the continent, respectively. Also, HPLC profiles showed important differences between U. molinae populations. In vitro antioxidant capaci...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Chemical and technological evaluation of the Phyllanthus niruri aerial parts as a function of cultivation and harvesting conditions
In conclusion, these results suggest that even under less favorable climatic conditions, in winter, the pruning seems to cause a strong influence over the P. niruri polyphenolics production. Indeed, the total flavonoids content, as well as the HPLC profile, can be used as indicative parameters of the ratio of leaves and stem in the vegetal raw material.
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Bioactive compounds in Bidens pilosa L. populations: a key step in the standardization of phytopharmaceutical preparations
The total flavonoid content (TFC), total polyphenols content (TPC), and in vitro antioxidant activity (AA) of six Bidens pilosa L., Asteraceae, populations harvested from different localities were evaluated in this work. The plants were separated in roots, stems, and leaves/flowers, and the influence of extraction methods was investigated.Areversed-phase high-performance liquid chromatography method (HPLC) was developed and employed to obtain characteristic HPLC fingerprints of the bioactive compounds present in the extractive solutions, which were correlated with the TFC, TPC, and AA. Extractive solutions of leaves/flower...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Phytotherapy in Brazil: recovering the concepts
This article shows the evolution of the Brazilian legislation in recent years in the area of herbal products and discusses the concept of phytotherapy in Brazil, bringing information about how it works in Europe.
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Herbal Reference Standards: applications, definitions and regulatory requirements
This review concerns the definitions and appropriate analytical characterisations of herbal reference standards within the framework of regulatory requirements. It describes currently applicable rules and regulations, as well as future issues relating to the European Pharmacopoeia and United States Pharmacopoeia. It provides an update on the use and availability of pharmacopoeial (EP and USP) herbal reference standards since our last review was published in 2009. The continuing challenges facing manufacturers, suppliers and analysts are discussed on the basis of exemplary reference substances for herbal products in medicin...
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Special issue on phytopharmaceutical technology
Source: Revista Brasileira de Farmacognosia - February 26, 2013 Category: Drugs & Pharmacology Source Type: research

Ziprasidone: First report of gingival pain: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Valsartan: Angioedema in an elderly patient: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Triamcinolone/lidocaine: Paraplegia from acute spinal cord infarction in an elderly patient: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Voriconazole: Hypersensitivity: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Vincristine overdose: Various toxicities in a child: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Warfarin: Epidural haematoma of the spinal cord: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Tamoxifen: Alopecia: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Tacrolimus: Hypersensitivity reaction to polyethoxylated castor oil: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Tacrolimus: Ischaemic optic neuropathy and posterior reversible encephalopathy syndrome: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Telaprevir: DRESS syndrome: 2 case reports
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Sorafenib: Hyponatraemia and thrombocytopenia in an elderly patient: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Sorafenib: Immune thrombocytopenic purpura: case report
Source: Reactions - February 26, 2013 Category: Drugs & Pharmacology Tags: Short communication Source Type: research