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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 6.
α(2)-µ-Globulin fragment (a2-f) from kidneys of male rats.
Abstract The structure of α(2)-µ-Globulin fragment (A2-f) is not known.α(2)-µ-Globulin fragment (A2-f) is a 15.5 kDa protein that binds equimolar amount of fatty acids in male rat kidneys. The expression of this protein has been shown to change in response to druginduced and genetic hypertension which suggests that it plays an important role in renal fatty acid metabolism under pathological conditions as well as normal conditions. A2-f has sequence homology with amino acid 28-178 of α(2)-µ-Globulin (A2U) that is synthesized pre-dominantly in the male rat liver and is present in the urine. It is believed that ...
Source: Bioinformation - February 25, 2013 Category: Bioinformatics Authors: Hai A, Kizilbash NA Tags: Bioinformation Source Type: research
Molecular modeling, dynamics studies and virtual screening of Fructose 1, 6 biphosphate aldolase-II in community acquired- methicillin resistant Staphylococcus aureus (CA-MRSA).
Abstract Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged as a nosocomial pathogen to the community which commonly causes skin and soft-tissue infections (SSTIs). This strain (MW2) has now become resistant to the most of the beta-lactam antibiotics; therefore it is the urgent need to identify the novel drug targets. Recently fructose 1,6 biphosphate aldolase-II (FBA) has been identified as potential drug target in CA-MRSA. The FBA catalyses the retro-ketolic cleavage of fructose-1,6-bisphosphate (FBP) to yield dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosph...
Source: Bioinformation - February 25, 2013 Category: Bioinformatics Authors: Yadav PK, Singh G, Gautam B, Singh S, Yadav M, Srivastav U, Singh B Tags: Bioinformation Source Type: research
SoyProDB: A database for the identification of soybean seed proteins.
Abstract Soybean continues to serve as a rich and inexpensive source of protein for humans and animals. A substantial amount of information has been reported on the genotypic variation and beneficial genetic manipulation of soybeans. For better understanding of the consequences of genetic manipulation, elucidation of soybean protein composition is necessary, because of its direct relationship to phenotype. We have conducted studies to determine the composition of storage, allergen and anti-nutritional proteins in cultivated soybean using a combined proteomics approach. Two-dimensional polyacrylamide gel electrophor...
Source: Bioinformation - February 25, 2013 Category: Bioinformatics Authors: Tavakolan M, Alkharouf NW, Khan FH, Natarajan S Tags: Bioinformation Source Type: research
Comparative Molecular docking analysis of DNA Gyrase subunit A in Pseudomonas aeruginosaPAO1.
Abstract Pseudomonas aeruginosa is an opportunistic bacterium known for causing chronic infections in cystic fibrosis and chronic obstructive pulmonary disease (COPD) patients. Recently, several drug targets in Pseudomonas aeruginosa PAO1 have been reported using network biology approaches on the basis of essentiality and topology and further ranked on network measures viz. degree and centrality. Till date no drug/ligand molecule has been reported against this targets.In our work we have identified the ligand /drug molecules, through Orthologous gene mapping against Bacillus subtilis subsp. subtilis str. 168 and pe...
Source: Bioinformation - February 25, 2013 Category: Bioinformatics Authors: Gupta A, Sharma V, Tewari AK, Surenderkumar V, Wadhwa G, Mathur A, Sharma SK, Jain CK Tags: Bioinformation Source Type: research
Impact of rtI233V mutation in hepatitis B virus polymerase protein and adefovir efficacy: Homology modeling and molecular docking studies.
In this study, it was attempted to evaluate the impact of putative rtI233V substitution on adefovir action by homology modeling and docking studies. The HBVrt nucleotide sequence containing rtI233V mutation was obtained from the treatment-naive chronic hepatitis B subject. The three dimensional model of HBV polymerase/rt was constructed using the HIV-1rt template (PDB code: 1RTD A) and the model was evaluated by the Ramachandran plot. Autodock was employed to dock the HBV polymerase/rt and adefovir. The modelled structure showed the amino acid rtI233 to be located away from the drug interactory site. The substitution of is...
Source: Bioinformation - February 25, 2013 Category: Bioinformatics Authors: Ismail AM, Sharma OP, Kumar MS, Kannangai R, Abraham P Tags: Bioinformation Source Type: research
Insight towards the conserved water mediated recognition of catalytic and structural Zn(+2) ions in human Matrix Metalloproteinase-8 enzyme: A study by MD-simulation methods.
Abstract Human matrix metalloproteinase-8 (hMMP-8) plays a important role in the progression of colorectal cancer, metastasis, multiple sclerosis and rheumetoid arthritis. Extensive MD-simulation of the PDB and solvated structures of hMMP-8 has revealed the presence of few conserved water molecules around the catalytic and structural zinc (ZnC and ZnS) ions. The coordination of two conserved water molecules (W and WS) to ZnS and the H-bonding interaction of WS to S151 have indicated the plausible involvement of that metal ion in the catalytic process. Beside this the coupling of ZnC and ZnS metal ions (ZnC - W(H) (...
Source: Bioinformation - February 25, 2013 Category: Bioinformatics Authors: Chakrabarti B, Bairagya HR, Mishra DK, Chatterjee PK, Mukhopadhyay BP Tags: Bioinformation Source Type: research
Isolation and Identification of hydrocarbon degrading bacteria from Ennore creek.
In this study we have investigated the ability of microorganisms present in the sediment sample to degrade these hydrocarbons, crude oil in particular, so that contaminated soils and water can be treated using microbes. Sediments samples were collected once in a month for a period of twelve months from area surrounding Ennore creek and screened for hydrocarbon degrading bacteria. Of the 113 crude oil degrading isolates 15 isolates were selected and cultivated in BH media with 1% crude oil as a sole carbon and energy source. 3 efficient crude oil bacterial isolates Bacillus subtilis I1, Pseudomonas aeruginosa I5 and Pseudom...
Source: Bioinformation - February 25, 2013 Category: Bioinformatics Authors: Subathra MK, Immanuel G, Suresh AH Tags: Bioinformation Source Type: research
Synthesis, and Biological Evaluations of Novel 7-[7-Amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-8-methoxyquinolines
with Potent Antibacterial Activity against Respiratory Pathogens
Journal of Medicinal ChemistryDOI: 10.1021/jm301650g
Source: Journal of Medicinal Chemistry - February 25, 2013 Category: Chemistry Authors: Takashi Odagiri, Hiroaki Inagaki, Yuichi Sugimoto, Masatoshi Nagamochi, Rie N. Miyauchi, Junichi Kuroyanagi, Takahiro Kitamura, Satoshi Komoriya and Hisashi Takahashi Source Type: research
Derivatives as Inhibitors of NF-κB/DNA Interaction: Synthesis,
Molecular Modeling, 3D-QSAR, and Biological Evaluation
Journal of Medicinal ChemistryDOI: 10.1021/jm3009647
Source: Journal of Medicinal Chemistry - February 25, 2013 Category: Chemistry Authors: Giovanni Marzaro, Adriano Guiotto, Monica Borgatti, Alessia Finotti, Roberto Gambari, Giulia Breveglieri and Adriana Chilin Source Type: research
Physical Properties and Formation Mechanism of Copper/Glass
Modified Laser Nanocrystals-Amorphous Reinforced Coatings
The Journal of Physical Chemistry CDOI: 10.1021/jp311138f
Source: The Journal of Physical Chemistry C - February 25, 2013 Category: Chemistry Authors: Jianing Li, Huijun Yu, Chuanzhong Chen and Shuili Gong Source Type: research
Simultaneous Occurrence of Three Different Valence
Tautomers in meso-Vinylruthenium-Modified Zinc Porphyrin Radical Cations
Journal of the American Chemical SocietyDOI: 10.1021/ja400673c
Source: Journal of the American Chemical Society - February 25, 2013 Category: Chemistry Authors: Jing Chen, Evelyn Wuttke, Walther Polit, Thomas Exner and Rainer F. Winter Source Type: research
Preparation, Structure, and Electrochemistry of Layered
Polyanionic Hydroxysulfates: LiMSO4OH (M = Fe, Co, Mn)
Electrodes for Li-Ion Batteries
Journal of the American Chemical SocietyDOI: 10.1021/ja3125492
Source: Journal of the American Chemical Society - February 25, 2013 Category: Chemistry Authors: Chinmayee V. Subban, Mohamed Ati, Gwenaëlle Rousse, Artem M. Abakumov, Gustaaf Van Tendeloo, Raphaël Janot and Jean-Marie Tarascon Source Type: research
High-Resolution Zero-Field NMR J-Spectroscopy
of Aromatic Compounds
Journal of the American Chemical SocietyDOI: 10.1021/ja312239v
Source: Journal of the American Chemical Society - February 25, 2013 Category: Chemistry Authors: John W. Blanchard, Micah P. Ledbetter, Thomas Theis, Mark C. Butler, Dmitry Budker and Alexander Pines Source Type: research
An Efficient and Faithful in Vitro Replication System
for Threose Nucleic Acid
Journal of the American Chemical SocietyDOI: 10.1021/ja3118703
Source: Journal of the American Chemical Society - February 25, 2013 Category: Chemistry Authors: Hanyang Yu, Su Zhang, Matthew R. Dunn and John C. Chaput Source Type: research
Chiral Gold Complex-Catalyzed Hetero-Diels–Alder
Reaction of Diazenes: Highly Enantioselective and General for Dienes
Journal of the American Chemical SocietyDOI: 10.1021/ja3110472
Source: Journal of the American Chemical Society - February 25, 2013 Category: Chemistry Authors: Bin Liu, Kang-Nan Li, Shi-Wei Luo, Jian-Zhou Huang, Huan Pang and Liu-Zhu Gong Source Type: research
Hierarchical Assembly of Collagen Peptide Triple Helices
into Curved Disks and Metal Ion-Promoted Hollow Spheres
Journal of the American Chemical SocietyDOI: 10.1021/ja307651e
Source: Journal of the American Chemical Society - February 25, 2013 Category: Chemistry Authors: David E. Przybyla, Charles M. Rubert Pérez, Jeremy Gleaton, Vikas Nandwana and Jean Chmielewski Source Type: research
Studies on the Structural
Characteristics of Gelled
Waxy Crude Oils Based on Scaling Model
Energy & FuelsDOI: 10.1021/ef301921b
Source: Energy and Fuels - February 25, 2013 Category: Chemistry Authors: Fei Yang, Chuanxian Li and Dan Wang Source Type: research
PICK1 (protein interacting with C kinase) and neurological disorders
Abstract Best known for its interaction with the α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) subunit GluA2 and for its influence on excitatory synapse activity, the protein interacting with protein kinase C, PICK1, is the focus of considerable attention from neurobiologists. Indeed, this PDZ domain‐containing protein has been shown to interact with a wide variety of neurotransmitter receptors, transporters and enzymes, including glutamate and nicotinic acetylcholine receptors, dopamine and glutamate transporters and the enzyme serine racemase. Through its lipid binding domain, PIC...
Source: Synapse - February 25, 2013 Category: Neurology Authors: Marylène C. Focant, Emmanuel Hermans Tags: Review Article Source Type: research
The Lipophilic Bullet Hits the Targets: Medicinal
Chemistry of Adamantane Derivatives
Chemical ReviewsDOI: 10.1021/cr100264t
Source: Chemical Reviews - February 25, 2013 Category: Chemistry Authors: Lukas Wanka, Khalid Iqbal and Peter R. Schreiner Source Type: research
ARPA-E Summit Reveals U.S. Energy Future
[caption id="attachment_11053" align="alignleft" width="385" caption="Bill Gates and Steven Chu have a "fireside" chat at the 2012 ARPA-e summit. Courtesy of Department of Energy."] [/caption]The future of energy will be on display at the fourth annual summit of the Advanced Research Projects Agency for Energy , or ARPA-e . But which future? [More]
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: Energy & Sustainability,Technology,More Science Source Type: research
No More OJ? An Invasive Insect Threatens the Citrus Industry (preview)
One day in 2005, just before Hurricane Katrina blew through Florida and devastated New Orleans, Susan Halbert stood before a pomelo tree on a farm outside Miami. Something about this tree did not look right. It seemed undernourished: its leaves were sparse, and its melon-size citrus fruit was lopsided. Yet all the other plants in the garden were thriving, and the woman who took care of them had carefully tended the pomelo with a fresh layer of fertilizer. “She clearly knew how to grow plants,” says Halbert, an entomologist for the Florida Department of Agriculture and Consumer Services (FDACS). [More]
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: More Science Source Type: research
New Geothermal Data System Could Open Up Clean-Energy Reserves
Geologic data does not come cheap, especially when you are using it to build a multimillion-dollar geothermal power plant. Just ask Susan Petty, president and chief technology officer at AltaRock Energy. Her company is part of a $43.8-million pilot project to tap thermal energy from Oregon's Newberry Volcano . Engineers are injecting water deep underground to fracture superheated rocks and create a geothermal reservoir. Their eventual goal is to recirculate pressurized steam back to the surface to test a new kind of technology called an enhanced geothermal system (EGS) . Unlike conventional power plants that rely on ne...
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: Energy & Sustainability,Technology,Society Policy,Everyday Science,More Science,Energy Technology,Alternative Energy Technology,Alternative Energy Technology,Clean Air Policy,Climate,Green Living,Energy Technology,Environment,Energy Source Type: research
Interaction of Pyridine Derivatives with a Gold (111)
Surface as a Model for Adsorption to Large Nanoparticles
The Journal of Physical Chemistry CDOI: 10.1021/jp309625h
Source: The Journal of Physical Chemistry C - February 25, 2013 Category: Chemistry Authors: Doreen Mollenhauer, Nicola Gaston, Elena Voloshina and Beate Paulus Source Type: research
Influence of Morphology and Crystallinity on Surface
Reactivity of Nanosized Anatase TiO2 Studied by Adsorption
Techniques. 2. Solid–Liquid Interface
The Journal of Physical Chemistry CDOI: 10.1021/jp3077084
Source: The Journal of Physical Chemistry C - February 25, 2013 Category: Chemistry Authors: Mouhamad Ali Ahmad, Benedicte Prelot, Fabien Dufour, Olivier Durupthy, Angelina Razafitianamaharavo, Jean Marc Douillard, Corinne Chaneac, Frédéric Villiéras and Jerzy Zajac Source Type: research
With So Much Good Writing, Is It Worth Struggling To Write Some More?
This is a guest blog post written by Akshat Rathi , a science writer based in the UK who regularly writes for The Economist and Chemistry World and blogs at Allotrope . -- [More]
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: More Science Source Type: research
Germany Investigates Possible Organic Egg Fraud
BERLIN (Reuters) - German authorities are investigating possible large-scale fraud by organic egg producers amid increased concern over food industry practices following Europe's horse meat scandal.The northern state of Lower Saxony, a major agricultural hub, has launched probes of some 150 farms suspected of wrongly selling eggs produced by hens kept in overcrowded conditions under the organic label.Two other states are investigating a further 50 farms."If the accusations (against the farms) are found to be true, then we are talking of fraud on a grand scale: fraud against consumers but also fraud against the many organic...
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: Energy & Sustainability,Environment,Society Policy,Green Living,Ecology,Biology,Everyday Science Source Type: research
Step Inside the Real World of Compulsive Hoarders
If you had opened the front door of Lee Shuer's apartment in the early 2000s, you would have encountered a narrow hallway made even narrower by all kinds of random stuff: unnervingly tall stacks of books and papers, cardboard boxes full of assorted knickknacks, and two hot pink salon hair dryer chairs with glass domes suspended from their arched necks. Sidling down the hallway to the right, you would have reached Shuer's bedroom. The door would have opened just wide enough for you to squeeze inside, where you would have seen mounds of stuff three to four feet high on the floor, bed and every available surface. A ty...
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: Mind & Brain,Language Linguistics,Language Linguistics,Thought Cognition,Neurological Disorders,Neuroscience,Psychiatry,Psychology,Mind Brain,Addiction Recovery Source Type: research
Pharmacokinetics of two common antiretroviral regimens in older HIV‐infected patients: a pilot study
ConclusionsThis study demonstrates that the PK of these ARVs are altered by 5–78% in an older HIV‐infected population. Implications of PK differences for clinical outcomes, particularly with the active nucleoside metabolites, remain to be explored. This study forms the basis for further study of ARV PK, efficacy, and toxicity in older HIV‐infected patients.
Source: HIV Medicine - February 25, 2013 Category: Infectious Diseases Authors: JB Dumond, JL Adams, HMA Prince, RL Kendrick, R Wang, SH Jennings, S Malone, N White, C Sykes, AH Corbett, KB Patterson, A Forrest, ADM Kashuba Tags: Original Research Source Type: research
R‐CHOP therapy alone in limited stage diffuse large B‐cell lymphoma
Summary Long‐term observation has identified a pattern of continuing relapse in limited stage diffuse large B‐cell lymphoma (DLBCL) treated by three cycles of R‐CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) plus involved‐field irradiation. We retrospectively analysed 190 untreated patients with limited stage DLBCL treated by R‐CHOP alone. All the patients were scheduled to undergo primary therapy with six cycles of full‐dose R‐CHOP. Cases with a dose reduction of more than 20% were excluded from the study. Additional local irradiation was allowed in patients with partial response (P...
Source: British Journal of Haematology - February 25, 2013 Category: Hematology Authors: Naoto Tomita, Hirotaka Takasaki, Kazuho Miyashita, Shin Fujisawa, Eriko Ogusa, Shiro Matsuura, Kumiko Kishimoto, Ayumi Numata, Atsuko Fujita, Rika Ohshima, Hideyuki Kuwabara, Maki Hagihara, Chizuko Hashimoto, Sachiya Takemura, Hideyuki Koharazawa, Etsuko Tags: Research Paper Source Type: research
Nathan Myhrvold Shares Cooking-Science Tips
“The best value for money in cooking equipment, in my mind, is first a digital scale and digital thermometer. They’re both about $20. They help you cook so much more accurately that they’re both enormously valuable.” [More]
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: More Science,Physics,Technology,More Science,Everyday Science,Chemistry,Society & Policy Source Type: research
The mystery mammal of Kayan Mentarang
Back in 2005, the discovery of a weird reddish, long-tailed mammal, photographed by a camera-trap at Kayan Mentarang in central Borneo, was announced by the Swiss World Wildlife Fund. I covered the case and how it unfolded back at Tet Zoo ver 1 during January 2007. That's such a long time ago that now is probably a good time to recycle the whole story. So, here it is again, with updates as and where appropriate. The big deal about the Kayan Mentarang animal is that it was hailed as a possible new species. [More]
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: Evolution Source Type: research
Omalizumab for the Treatment of Chronic Idiopathic or Spontaneous Urticaria
New England Journal of Medicine, Volume 0, Issue 0, Ahead of Print.
Source: New England Journal of Medicine - February 25, 2013 Category: Internal Medicine Tags: article Source Type: research
Azathioprine and mercaptopurine in the management of patients with chronic, active microscopic colitis
ConclusionsIn this retrospective case series, the majority of chronic, active MC patients were intolerant to AZA leading to cessation of treatment. However, further studies are needed to explore the efficacy, acceptance, tolerance and safety of MP in patients with chronic, active MC refractory to budesonide.
Source: Alimentary Pharmacology and Therapeutics - February 25, 2013 Category: Drugs & Pharmacology Authors: A. Münch, F. Fernandez‐Banares, L. K. Munck Tags: Original Article Source Type: research
Guest Post: Export Shale Revolution Rather than Gas
By Kevin Jianjun Tu and David Livingston [More]
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: Energy & Sustainability Source Type: research
A randomized controlled clinical multicenter trial comparing the clinical and histological performance of a new, modified polylactide‐co‐glycolide acid membrane to an expanded polytetrafluorethylene membrane in guided bone regeneration procedures
ConclusionPeri‐implant GBR was successfully performed using either of the membranes. The control membrane was able to better maintain the horizontal thickness of regenerated bone and revealed less soft tissue complications. No statistically valid evidence about the superiority of one membrane was found in any other parameters. Soft tissue dehiscences occur with both types of membranes and can impair the amount of regenerated bone.
Source: Clinical Oral Implants Research - February 25, 2013 Category: Dentistry Authors: David Schneider, Franz E. Weber, Ueli Grunder, Claude Andreoni, Rino Burkhardt, Ronald E. Jung Tags: Original Article Source Type: research
Risk indicators associated with dental erosion among Jordanian school children aged 12–14 years of age
ConclusionsDental erosion is a multifactorial condition in which mouth dryness, vomiting, cortisol inhaler use, keeping soft drinks in the mouth, drinking beverages at bed time, consumption of lemon, sour candies, and having confectionary as snacks are risk indicators, and area of residence are all potential factors.
Source: International Journal of Paediatric Dentistry - February 25, 2013 Category: Dentistry Authors: Abed Al‐Hadi Hamasha, Feda I. Zawaideh, Roua Thamer Al‐Hadithy Tags: Original Article Source Type: research
Effect of solvent evaporation strategies on regional bond strength of one‐step self‐etch adhesives to root canal dentine
ConclusionThe use of paper points with additional air‐blowing for removing excessive adhesive and evaporating residual water/solvent would be effective in producing higher bond strength for the tested one‐step self‐etch adhesives and fewer blister formations in deeper regions of the post space.© 2013 International Endodontic Journal. Published by Blackwell Publishing Ltd
Source: International Endodontic Journal - February 25, 2013 Category: Dentistry Authors: S. Thitthaweerat, M. Nakajima, R. M. Foxton, J. Tagami Tags: Original Scientific Article Source Type: research
In memoriam: robert cotter.
Authors: PMID: 23426867 [PubMed - in process]
Source: Mass Spectrometry Reviews - February 25, 2013 Category: Molecular Biology Tags: Mass Spectrom Rev Source Type: research
Selected reviews on mass spectrometric topics-CLXIII.
PMID: 23426868 [PubMed - in process]
Source: Mass Spectrometry Reviews - February 25, 2013 Category: Molecular Biology Authors: Budzikiewicz H Tags: Mass Spectrom Rev Source Type: research
Avoiding bladder catheterisation in total knee arthroplasty: Patient selection criteria and low‐dose spinal anaesthesia
ConclusionLow‐dose spinal anaesthesia combined with simple selection criteria allowed for early mobilisation (96%) and avoidance of bladder catheterisation in the vast majority (88%) of patients undergoing total knee arthroplasty, and the rest (12%) only needed a single temporary catheterisation.
Source: Acta Anaesthesiologica Scandinavica - February 25, 2013 Category: Anesthesiology Authors: S. KARASON, T. A. OLAFSSON Tags: Original Article Source Type: research
Whole grain foods and health - a Scandinavian perspective.
The objective of the current paper is to clarify possible differences in nutritional and health effects of the types of whole grain grown and consumed in the Scandinavian countries. A further objective is to substantiate how processing may influence the nutritional value and potential health effects of different whole grains and whole grain foods. The most commonly consumed whole grain cereals in the Scandinavian countries are wheat, rye, and oats with a considerable inter-country variation in the consumption patterns and with barley constituting only a minor role. The chemical composition of these different whole grains a...
Source: Food and Nutrition Research - February 25, 2013 Category: Nutrition Authors: Frølich W, Aman P, Tetens I Tags: Food Nutr Res Source Type: research
Immunization with 60 kD Ro peptide produces different stages of pre‐clinical autoimmunity in a Sjögren's syndrome‐model among multiple strains of inbred mice
Abstract Sjögren's syndrome is a chronic illness characteristically manifested by immune injury to the salivary and lacrimal glands, resulting in dry mouth/eyes. Anti‐Ro (SSA) and anti‐La (SSB) autoantibodies are frequently found in Sjögren's subjects as well as individuals that will go on to develop the disease. Immunization of BALB/c mice with Ro60 peptides results in epitope spreading with anti‐Ro and anti‐La along with lymphocyte infiltration of salivary glands similar to human Sjögren's. In addition, these animals have poor salivary function/low saliva volume. Here, we examined whether Ro‐peptide immuniza...
Source: Clinical and Experimental Immunology - February 25, 2013 Category: Allergy & Immunology Authors: Biji T. Kurien, Anil Dsouza, Ann Igoe, Yun Jong Lee, Jacen S. Maier‐Moore, Tom Gordon, Michael Jackson, R. Hal Scofield Tags: Original Article Source Type: research
ExecuCare: Outpatient Treatment for Impaired Professionals
Conclusions: Intensive outpatient programs are a necessary and effective level of care for impaired professionals. These programs can provide an initial level of treatment for about 30% of impaired professional and frequently decrease the need for inpatient or residential treatment. A local, professional, comprehensive outpatient addictions program like the one presented supports professionals’ recovery by supporting reintegration into the work setting and decreasing relapse potential.
Source: Addictive Disorders and Their Treatment - February 25, 2013 Category: Addiction Tags: Original Articles Source Type: research
Of course I'm stressed, I'm in cookie withdrawal.
I don't know about you guys, but in times of stress, I eat my feelings. And I mean, why wouldn't I? My feelings are delicious! The taste like popcorn and peanut butter M&Ms and fudge and pepperoni pizza.But then, when the stressful times are over, well, I've got to go back to eating salads and kale and cabbage and maybe not eating a whole bag of chocolate EVERY night of the week. [More]
Source: Scientific American - Official RSS Feed - February 25, 2013 Category: Science Tags: Mind & Brain Source Type: research
Supreme Court Skeptical Of Patent Challenge
Biotech: Justices seem receptive to protecting company’s GM seeds
Source: Chemical and Engineering News - February 25, 2013 Category: Chemistry Authors: Glenn Hess Source Type: research
European Producers’ 2012 Earnings Stifled By Ongoing Economic Recession
Chemical Earnings: Full-year results are lackluster with no economic pickup in sight
Source: Chemical and Engineering News - February 25, 2013 Category: Chemistry Authors: Alex Scott Source Type: research
Informex Attendees Report Strong Business
Fine Chemicals: Fine and custom chemical firms buoyed by return of business from Asia
Source: Chemical and Engineering News - February 25, 2013 Category: Chemistry Authors: Rick Mullin Source Type: research
Suicide and the sufficiency of surrogate decision makers.
PMID: 23428024 [PubMed - in process]
Source: The American Journal of Bioethics : AJOB - February 25, 2013 Category: Medical Ethics Authors: Taye H, Magnus D Tags: Am J Bioeth Source Type: research
Withdrawal of nonfutile life support after attempted suicide.
Abstract End-of-life decision making is fraught with ethical challenges. Withholding or withdrawing life support therapy is widely considered ethical in patients with high treatment burden, poor premorbid status, or significant projected disability even when such treatment is not "futile." Whether such withdrawal of therapy in the aftermath of attempted suicide is ethical is not well established in the literature. We provide a clinical vignette and propose criteria under which such withdrawal would be ethical. We suggest that it is appropriate to withdraw life support, regardless of the cause of the critical illnes...
Source: The American Journal of Bioethics : AJOB - February 25, 2013 Category: Medical Ethics Authors: Brown SM, Elliott CG, Paine R Tags: Am J Bioeth Source Type: research