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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 34.

[In Process Citation].
PMID: 23384926 [PubMed - in process]
Source: Praxis - January 2, 2013 Category: Journals (General) Authors: Schultz C, Koneth I, Schmid HP Tags: Praxis (Bern 1994) Source Type: research

Spontaneous Ventral Herniation of the Gallbladder.
PMID: 23287655 [PubMed - as supplied by publisher]
Source: The American Journal of the Medical Sciences - January 2, 2013 Category: Journals (General) Authors: El-Bakush A, Sherif K, Kambali S, Flathouse R, Quattromani F, Jumper C Tags: Am J Med Sci Source Type: research

Control of AA amyloidosis complicating Crohn's disease: a clinico‐pathological study
Abstract Amyloidosis complicating Crohn's disease (CD) was described for the first time in 1949 [1]. In 1992, amyloidosis was reported in 22/1,709 (0.9%) CD cases and 3/1,341 (0.07%) ulcerative colitis (UC) patients; death due to renal failure occurred in 45% of the CD patients [2]. Major advances in science have unravelled the molecular biology and pathophysiology underlying the different forms of amyloidosis [3‐4]. A common phenomenon is the misfolding of various proteins and the formation of insoluble amyloid non‐branching fibrils, which consist of β‐pleated sheet polypeptides identified by Congo red staining; th...
Source: European Journal of Clinical Investigation - January 2, 2013 Category: Journals (General) Authors: Marie Armelle Denis, Jean‐Pierre Cosyns, Alexandre Persu, Olivier Dewit, Chantal Galocsy, Pierre Hoang, Philippe Maldague, Pierre Wallemacq, Frank Zerbib, René Fiasse Tags: Original Paper Source Type: research

[Giant congenital naevus.]
PMID: 23290659 [PubMed - as supplied by publisher]
Source: Presse Medicale - January 2, 2013 Category: Journals (General) Authors: Lorette G, Le Touze A, Maruani A Tags: Presse Med Source Type: research

Alphaherpesvirinae and Gammaherpesvirinae glycoprotein L and CMV UL130 originate from chemokines
Herpesviridae is a large family of DNA viruses divided into three subfamilies: Alpha-, Beta- and Gammaherpesvirinae. The process of herpesvirus transmission is mediated by a range of proteins, one of which is glycoprotein L (gL). Based on our analysis of the solved structures of HSV2 and EBV gH/gL complexes, we propose that Alphaherpesvirinae and Gammaherpesvirinae glycoprotein L and Betaherpesvirinae UL130 originate from chemokines. Herpes simplex virus type 2 gL and human cytomegalovirus homolog (UL130) adopt a novel C chemokine-like fold, while Epstein-Barr virus gL mimics a CC chemokine structure. Hence, it is possible...
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: Maja MalkowskaKatarzyna KokoszynskaMagdalena DymeckaLeszek RychlewskiLucjan S Wyrwicz Source Type: research

PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus
Conclusions: MKP-7, independently of PI3K/Akt pathway, played a key role in downregulation of JNK activity after ischemia in the rat hippocampus, and the export of MKP-7 from the nucleus was involved in downregulation of cytoplasmic JNK activity in response to ischemic stimuli.
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: JianXi ZhuWei ShenLi GaoHao GuShuTong ShenYi WangHuiWen WuJun Guo Source Type: research

A polymorphism associated with increased levels of YKL-40 and the risk of early onset of lone atrial fibrillation
Conclusions: The (-131CG) genotype was not associated with increased risk of AF. Genetically increased YKL-40 levels were not associated to AF.
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: Kristoffer M HenningsenMorten S OlesenGolnaz SajadiehStig HaunsoeJesper H Svendsen Source Type: research

Towards elimination of maternal deaths: maternal deaths surveillance and response
Current methods for estimating maternal mortality lack precision, and are not suitable for monitoring progress in the short run. In addition, national maternal mortality ratios (MMRs) alone do not provide useful information on where the greatest burden of mortality is located, who is concerned, what are the causes, and more importantly what sub-national variations occur. This paper discusses a maternal death surveillance and response (MDSR) system. MDSR systems are not yet established in most countries and have potential added value for policy making and accountability and can build on existing efforts to conduct maternal ...
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: Sennen HountonLuc De BernisJulia HusseinWendy J GrahamIsabella DanelPeter ByassElizabeth M Mason Source Type: research

The bHLH transcription factor SPATULA regulates root growth by controlling the size of the root meristem
Conclusions: Our data suggest that SPT functions in growth control throughout sporophytic growth of Arabidopsis, but is not necessary for cell fate decisions except during carpel development. SPT functions independently of gibberellic acid during root development, but may play a role in regulating auxin transport or accumulation. Our data suggests that SPT plays a role in control of root growth, similar to its roles in above ground tissues.
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: Srilakshmi MakkenaRebecca S Lamb Source Type: research

A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep
Conclusion: We have identified a missense mutation in the bioactive part of the GDF9 protein that shows strong association with litter size in NWS. Based on the NWS breeding history and the marked increase in the c.1111A allele frequency in the AI ram population since 1983, we hypothesize that c.1111A allele originate from Finnish landrace imported to Norway around 1970. Because of the widespread use of Finnish landrace and the fact that the ewes homozygous for the c.1111A allele are reported to be fertile, we expect the commercial impact of this mutation to be high.
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: Dag I VågeMaren HusdalMatthew P KentGunnar KlemetsdalInger A Boman Source Type: research

Overexpression of aldo-keto-reductase in azole-resistant clinical isolates of Candida glabrata determined by cDNA-AFLP
Background: Candida glabrata causes significant medical problems in immunocompromised patients. Many strains of this yeast are intrinsically resistant to azole antifungal agents, and treatment is problematic, leading to high morbidity and mortality rates in immunosuppressed individuals. The primary goal of this study was to investigate the genes involved in the drug resistance of clinical isolates of C. glabrata. Methods: The clinical isolates of C. glabrata were collected in an epidemiological survey of candidal infection in immunocompromised patients and consisted of four fluconazole and itraconazole resistant isolates, ...
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: Shirin FarahyarFarideh ZainiParivash KordbachehSassan RezaieMahin SafaraReza RaoofianMansour Heidari Source Type: research

Comparative gene expression supports the origin of the incisor and molar process from a single endite in the mandible of the red flour beetle Tribolium castaneum
Conclusions: Comparative gene expression suggests that the Tribolium mandible has a single endite from which both mandible lobes are derived. Our results do not support Machida's hypothesis homologising the incisor and molar processes of the mandible to the galea and lacinia endites of the maxilla. We propose, instead, that both incisor and molar processes are derived from a single endite serially homologous to the lacinia of the maxilla.
Source: BioMed Central - January 2, 2013 Category: Journals (General) Authors: Joshua F CoulcherMaximilian J Telford Source Type: research

Academic medicine: vision to reality.
PMID: 23417584 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Krishnan RR, Ng I Tags: Ann Acad Med Singapore Source Type: research

Successful ageing in singapore-a viable goal?
PMID: 23417585 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Mahendran R, Feng L, Ng TP, Kua EH Tags: Ann Acad Med Singapore Source Type: research

Short- and long-term outcomes at 2, 5 and 8 years old for neonates at borderline viability-an 11-year experience.
Conclusion: Our results indicated that local fi gures for mortality and morbidity remained high at the limits of viability, although they were comparable to outcomes for large scale studies in advanced countries. PMID: 23417586 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Poon WB, Ho SK, Yeo CL Tags: Ann Acad Med Singapore Source Type: research

Get "real" with hysteroscopy using the pig bladder: a "uterine" model for hysteroscopy training.
Conclusion: This lowcost novel model provides realistic tissue resistance and yields an almost anatomically accurate hysteroscopic training tool, thereby allowing trainees to effectively acquire both diagnostic and therapeutic hysteroscopic skills. PMID: 23417587 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Ng YW, Fong YF Tags: Ann Acad Med Singapore Source Type: research

Electrocardiograph changes, troponin levels and cardiac complications after orthopaedic surgery.
Conclusion: Electrocardiograph changes do not necessarily accompany troponin elevations after the emergency orthopaedic surgery but are more likely to have higher troponin levels. The best predictor of postoperative cardiac complications is troponin elevation. PMID: 23417588 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Chong CP, Gaal WJ, Profitis K, Ryan JE, Savige J, Lim WK Tags: Ann Acad Med Singapore Source Type: research

Cognitive aspect of diagnostic errors.
Abstract Diagnostic errors can result in tangible harm to patients. Despite our advances in medicine, the mental processes required to make a diagnosis exhibits shortcomings, causing diagnostic errors. Cognitive factors are found to be an important cause of diagnostic errors. With new understanding from psychology and social sciences, clinical medicine is now beginning to appreciate that our clinical reasoning can take the form of analytical reasoning or heuristics. Different factors like cognitive biases and affective infl uences can also impel unwary clinicians to make diagnostic errors. Various strategies have b...
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Phua DH, Tan NC Tags: Ann Acad Med Singapore Source Type: research

Is cost-effective healthcare compatible with publicly financed academic medical centres?
Abstract Probably more than any country, Singapore has made signifi cant investment into the biomedical enterprise as a proportion of its economy and size. This focus recently witnessed a shift towards a greater emphasis on translational and clinical development. Key to the realisation of this strategy will be Academic Medical Centres (AMCs), as a principal tool to developing and applying useful products for the market and further improving health outcomes. Here, we explore the principal value proposition of the AMC to Singapore society and its healthcare system. We question if the values inherent within academic m...
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Chia WK, Toh HC Tags: Ann Acad Med Singapore Source Type: research

Treatment of Coronary In-stent Restenosis with Drug-eluting Balloon Catheter: Real-world Outcome and Literature Review.
PMID: 23417591 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Xia HY, Low AF, Lee CH, Teo SG, Chan M, Chan KH, Tan HC Tags: Ann Acad Med Singapore Source Type: research

Lemierre's Syndrome: An Unusual Cause of Calf Abscess.
PMID: 23417592 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Soh T, Lim MH Tags: Ann Acad Med Singapore Source Type: research

Low-grade fibromyxoid sarcoma of the thyroid: a case report.
PMID: 23417593 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - January 1, 2013 Category: Journals (General) Authors: Dong W, Zhang H Tags: Ann Acad Med Singapore Source Type: research

Towards a hospital-wide integrated systemfor quality and safety of health care.
Abstract No abstract available. PMID: 23412816 [PubMed - as supplied by publisher]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Levi M Tags: Neth J Med Source Type: research

Vascular manifestations of systemic lupus erythematosis.
Abstract Systemic lupus erythematosus (SLE) is an autoimmune connective disease, where vascular lesions are one of the typical symptoms. The differentiation of the type of vascular complications in SLE is very difficult, sometimes impossible, and requires an in-depth immune and histopathological approach, and extensive clinical experience. It may play a key role in the choice of treatment strategy and prediction of patient prognosis. SLE is a prototype of a multisystem autoimmune connective tissue disease, marked by immune complex-mediated lesions of blood vessels in diverse organs. Therefore, awareness of the aeti...
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Radic M, Martinovic Kaliterna D, Radic J Tags: Neth J Med Source Type: research

Primary symptomatic adrenal insufficiency induced by megestrol acetate.
Abstract Megestrol acetate (MA) is a progestational agent for the treatment of metastatic breast cancer and endometrial cancer. MA has also been used to promote weight gain in malnourished elderly patients, in patients with immunodeficiency virus and in cancer-induced cachexia. In addition to thromboembolic disease, MA may induce hyperglycaemia, osteoporosis, suppression of the gonadal axis, and Cushing's syndrome. MA has also been shown to cause symptomatic suppression of the hypothalamic-pituitary-adrenal (HPA) axis owing to its intrinsic glucocorticoid-like effect. Three additional patients are presented who dev...
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Delitala AP, Fanciulli G, Maioli M, Piga G, Delitala G Tags: Neth J Med Source Type: research

Course of HbA1c in non-diabetic pregnancy related to birth weight.
Conclusions: HbA1c is lower in all three trimesters of normal pregnancy compared with the level in non-pregnant women, and the change in HbA1c from the first to the second trimester predicts (the percentile of) birth weight. This could implicate that in order to prevent macrosomia in pregnant women with diabetes one should aim at lower HbA1c levels than the internationally accepted level, and at a decrease in HbA1c from the first to the second trimester. PMID: 23412819 [PubMed - in process]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Versantvoort AR, van Roosmalen J, Radder JK Tags: Neth J Med Source Type: research

Polyomavirus BK in the pathogenesis of bladder cancer.
Abstract Polyomaviruses are able to drive malignant transformation in rodent models, and have been implicated in the aetiology of a variety of human malignancies. However, the reports on this association in humans are strongly conflicting. Here we describe a renal transplant (RT) recipient with ureteral stenosis against the background of polyomavirus BK (BKV) activity. Six and a half years after transplantation, this patient developed metastasised bladder cancer. Prior to the diagnosis of cancer, atypical cells were detected in the urine that were denoted as 'decoy cells': virally infected epithelial cells that are...
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: van Aalderen MC, Yapici U, van der Pol JA, de Reijke TM, van Donselaar-van der Pant KA, Florquin S, Bemelman FJ, Ten Berge IJ Tags: Neth J Med Source Type: research

Familial LCAT deficiency: from renal replacement to enzyme replacement.
We present two brothers with considerable variation in the age at which they developed ESRD. Kidney biopsies revealed both tubular and glomerular pathology. To date, no causal therapy is available, yet enzyme replacement therapy is in development. PMID: 23412821 [PubMed - in process]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Stoekenbroek RM, van den Bergh Weerman MA, Hovingh GK, Potter van Loon BJ, Siegert CE, Holleboom AG Tags: Neth J Med Source Type: research

Unilateral tongue atrophy and pulmonary malignancy.
Abstract No abstract available. PMID: 23412822 [PubMed - as supplied by publisher]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Schulkes KJ, Bossink AW Tags: Neth J Med Source Type: research

A patient with cutaneous lesions after liver transplantation.
Abstract No abstract available. PMID: 23412823 [PubMed - as supplied by publisher]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Olde Bekkink M, Diercks GF, van den Berg AP, Tack CJ Tags: Neth J Med Source Type: research

Generalised tonic-clonic seizure and diffuse alveolar haemorrhage.
Abstract No abstract available. PMID: 23412824 [PubMed - as supplied by publisher]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Bachmeyer C, Ferrari M, Muresan IP, d'Huart S, Langman B, Parrot A Tags: Neth J Med Source Type: research

Evaluation of the threshold value for the Early Warning Score on general wards.
Conclusion: Raising the EWS threshold to 4 on general wards in the hospital would lead to an unacceptable decrease in sensitivity. Therefore, we recommend that the pre-defined cut-off should remain 3, with the possibility to personalise the threshold. PMID: 23412825 [PubMed - in process]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: van Rooijen CR, de Ruijter W, van Dam B Tags: Neth J Med Source Type: research

Registering complications at admission via the emergency department: an opportunity for improvement.
Conclusion: Complications are a major reason for hospitalisation. Registering complications present at admission gives broad insight into the complications following the care doctors provide. It is important to understand these complications better to prevent such admissions. PMID: 23412826 [PubMed - in process]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Magdelijns FJ, Gulikers D, Pijpers E, Koopmans RP, Stassen PM Tags: Neth J Med Source Type: research

Dominant type III hyperlipoproteinaemia (familial dysbetalipoproteinaemia).
Abstract No abstract available. PMID: 23412827 [PubMed - as supplied by publisher]
Source: The Netherlands Journal of Medicine - January 1, 2013 Category: Journals (General) Authors: Stalenhoef AF Tags: Neth J Med Source Type: research

Peripartum cardiomyopathy: when labour turns to heartbreak.
PMID: 23338907 [PubMed - in process]
Source: Singapore Medical Journal - January 1, 2013 Category: Journals (General) Authors: Tay EL, Yip JW, Poh KK Tags: Singapore Med J Source Type: research

Electrocardiography series. ECG P wave abnormalities.
Abstract P wave abnormalities are commonly found on ECG. However, they are seldom discussed and may also be neglected during ECG interpretion. In this article, we discuss two common types of P wave abnormalities, 'P mitrale' and 'P pulmonale'. The former was found in a patient with mitral valve stenosis, while the latter was from a patient with pulmonary hypertension. Echocardiography is important in evaluating the causes of P wave abnormalities. PMID: 23338908 [PubMed - in process]
Source: Singapore Medical Journal - January 1, 2013 Category: Journals (General) Authors: Tan LL, Teo SG, Poh KK Tags: Singapore Med J Source Type: research

Sun Yat-sen (1866-1925): Physician revolutionist.
PMID: 23338909 [PubMed - in process]
Source: Singapore Medical Journal - January 1, 2013 Category: Journals (General) Authors: Tan SY, Yip A Tags: Singapore Med J Source Type: research

PILL series. Doctor, my dentist wants your opinion.
Abstract Dental surgery is very common, and it is important for our dental colleagues to understand the medical history and chronic medications of our co-managed patients. Antibiotic prophylaxis is currently recommended only for patients at high risk for infective endocarditis when undergoing high-risk dental procedures. Good dental hygiene can prevent more infective endocarditis than prophylactic antibiotic therapy, as transient bacteraemia is common in daily activities such as the brushing and flossing of teeth. Most dental surgeries can generally be performed on patients taking a daily dose of aspirin, but the d...
Source: Singapore Medical Journal - January 1, 2013 Category: Journals (General) Authors: Chee FY, How CH Tags: Singapore Med J Source Type: research

Coronary computed tomography angiography with prospective electrocardiography triggering: a systematic review of image quality and radiation dose.
Abstract The purpose of this study was to perform a systematic review of the diagnostic accuracy, image quality and radiation dose of prospective electrocardiography (ECG)-triggered coronary computed tomography angiography (CCTA). We searched databases containing studies of CCTA that used prospective ECG-triggering between 2008 and 2011. The effective dose and image quality reported in each study were analysed and compared between the types of multislice CT scanners. We identified 23 studies through this search, with mean assessable coronary segments and effective dose at 96.8% (95% confidence level [CI] 83%, 100%)...
Source: Singapore Medical Journal - January 1, 2013 Category: Journals (General) Authors: Sabarudin A, Sun Z, Ng KH Tags: Singapore Med J Source Type: research

Peripartum cardiomyopathy: experience in an Asian tertiary centre.
Conclusion: PPCM remains a rare condition and appears to occur more commonly in Malay patients. Smoking and pregnancy-induced hypertension appear to be significant risk factors. While short-term outcome remains excellent, collaborative studies with other tertiary centres will help enhance our understanding of the long-term management of and clinical outcomes in these patients. PMID: 23338912 [PubMed - in process]
Source: Singapore Medical Journal - January 1, 2013 Category: Journals (General) Authors: Lim CP, Sim KL Tags: Singapore Med J Source Type: research