Journals (General) Top 20 This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

[In Process Citation].
We report a case of an 88-year old male patient with known chronic lower back pain who presented in late August with progressive pain in his right knee and lower leg as well as paraesthesias. Diagnostic work-up revealed an acute Lyme-Borreliosis. PMID: 23735767 [PubMed - in process] (Source: Praxis)
Source: Praxis - June 1, 2013 Category: Journals (General) Authors: Winnik S, Hitz A, Wyden S, Peter U, Eriksson U, Stieger R Tags: Praxis (Bern 1994) Source Type: research

Human papillomavirus vaccine in boys: background rates of potential adverse events.
CONCLUSIONS: Routinely collected health outcome administration data can inform postlicensure safety surveillance of target conditions that might be perceived as AEFI. PMID: 23725271 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - June 8, 2013 Category: Journals (General) Authors: Clothier HJ, Lee KJ, Sundararajan V, Buttery JP, Crawford NW Tags: Med J Aust Source Type: research

Gastric cancer risk with pernicious anemia: meta-analysis
NEW YORK (Reuters Health) - Patients with pernicious anemia have an increased relative risk of developing gastric cancer, a meta-analytic review of relevant studies confirms. (Source: Modern Medicine)
Source: Modern Medicine - December 21, 2012 Category: Journals (General) Source Type: news

Complementary and alternative medicine in paediatrics: a systematic overview/synthesis of Cochrane Collaboration reviews.
CONCLUSIONS: Given the disproportionate number of inconclusive reviews, there is an ongoing need for high quality research to assess the potential role of CAM in children. Unless the study of CAM is performed to the same science-based standards as conventional therapies, CAM therapies risk being perpetually marginalised by mainstream medicine. PMID: 23740212 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - June 8, 2013 Category: Journals (General) Authors: Meyer S, Gortner L, Larsen A, Kutschke G, Gottschling S, Gräber S, Schroeder N Tags: Swiss Med Wkly Source Type: research

Progestin as an alternative treatment option for multi-treated recurrent triple-negative breast cancer.
CONCLUSIONS: Progestins (MPA/MA) are an alternative treatment option for multi-treated recurrent TNBC. PMID: 23740185 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - June 8, 2013 Category: Journals (General) Authors: Meng X, Wu S, Jiang Z, Sun B, Ma Y, Zhao X, Ding L, Wang Y, Wang T, Zhang S, Song S Tags: Swiss Med Wkly Source Type: research

Risk assessment to guide prostate cancer screening decisions: a cost-effectiveness analysis.
Conclusions were sensitive to the estimated quality-of-life impacts of prostate cancer treatment as well as the incidence of cancers not detected by screening tests (poorer prognosis) and those that were detected by screening tests (better prognosis). The base-case incremental cost-effectiveness ratio of PSA screening was $291 817 per QALY for men with average risk, $110 726 per QALY for men with two times the average risk, and $30 572 per QALY for men with five times the average risk. CONCLUSIONS: PSA screening was not found to be cost-effective for men at an average-to-high risk of prostate cancer, but may be c...
Source: Med J Aust - June 8, 2013 Category: Journals (General) Authors: Martin AJ, Lord SJ, Verry HE, Stockler MR, Emery JD Tags: Med J Aust Source Type: research

The diagnosis of food allergy: protocol for a systematic review
DiscussionDecisions on which tests to use need to be guided by availability of tests, populations being cared for, risks, financial considerations and test properties. This review will examine papers from around the world, covering children and adults with suspected food allergy in varying populations and concentrated on four type of tests: APT, SPT, specific-IgEs, and component specific-IgEs. (Source: BioMed Central)
Source: BioMed Central - June 6, 2013 Category: Journals (General) Authors: Karla Soares-WeiserSukhmeet S PanesarTamara RaderYemisi TakwoingiThomas WerfelAntonella MuraroKarin Hoffmann-SommergruberGraham RobertsAziz Sheikh Source Type: research

Head-to-head comparison of fee-for-service and diagnosis related groups in two tertiary referral hospitals in Switzerland: an observational study.
This study suggested that the AP-DRG hospital showed higher patient satisfaction regarding discharge, lower re-hospitalisation rates and shorter LOS partly explained by a lower burden of co-morbidities and disease severity. This study needs validation in a larger cohort of patients and at multiple time points. PMID: 23740092 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - June 8, 2013 Category: Journals (General) Authors: Weissenberger N, Thommen D, Schuetz P, Mueller B, Reemts C, Holler T, Schifferli JA, Gerber M, Hug BL Tags: Swiss Med Wkly Source Type: research

Patterns of care for men diagnosed with prostate cancer in Victoria from 2008 to 2011.
CONCLUSION: Our data reveal a considerable "stage migration" towards earlier diagnosis of prostate cancer in Victoria and a large increase in the use of radical prostatectomy among men with clinically localised disease. PMID: 23725268 [PubMed - in process] (Source: Med J Aust)
Source: Med J Aust - June 8, 2013 Category: Journals (General) Authors: Evans SM, Millar JL, Davis ID, Murphy DG, Bolton DM, Giles GG, Frydenberg M, Andrianopoulos N, Wood JM, Frauman AG, Costello AJ, McNeil JJ Tags: Med J Aust Source Type: research

Hepatitis B and C in Switzerland - healthcare provider initiated testing for chronic hepatitis B and C infection.
Abstract Hepatitis B and hepatitis C are contagious liver diseases caused by the hepatitis B virus (HBV) and the hepatitis C virus (HCV), respectively. In particular, chronic infection with HBV or HCV is a major public health problem throughout Europe. The majority of persons chronically infected (65%-75%) are not aware of their infection status until symptoms of advanced liver disease appear. In addition, the peak in the number of patients suffering from advanced stages of the disease, such as cirrhosis and hepatocellular carcinoma, has not yet been reached. In order to reduce the current and future morbidity and ...
Source: Swiss Medical Weekly - June 8, 2013 Category: Journals (General) Authors: Fretz R, Negro F, Bruggmann P, Lavanchy D, De Gottardi A, Pache I, Masserey Spicher V, Cerny A Tags: Swiss Med Wkly Source Type: research

[Articles] Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis
Our analysis suggests that previous estimates of dementia burden, based on smaller datasets, might have underestimated the burden of dementia in China. The burden of dementia seems to be increasing faster than is generally assumed by the international health community. Rapid and effective government responses are needed to tackle dementia in low-income and middle-income countries. (Source: LANCET)
Source: LANCET - June 6, 2013 Category: Journals (General) Authors: Kit Yee Chan, Wei Wang, Jing Jing Wu, Li Liu, Evropi Theodoratou, Josip Car, Lefkos Middleton, Tom C Russ, Ian J Deary, Harry Campbell, Wei Wang, Igor Rudan, on behalf of the Global Health Epidemiology Reference Group (GHERG) Tags: Articles Source Type: research

Tolerance of intravenous methylprednisolone for relapse treatment in demyelinating CNS disease.
CONCLUSION: Therapy was well tolerated without severe side effects in CIS and MS patients. Sleep efficiency was not disturbed. In conclusion there are no obstacles to change from an inpatient to an outpatient setting for the steroid treatment of relapses in MS and CIS, but rare psychotic reactions to steroid treatment are not predictable. PMID: 23740464 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - June 8, 2013 Category: Journals (General) Authors: Lienert C, Schawalder G, Findling O, Kamm C, Humpert S, Mugglin A, Mathis J, Sturzenegger M, Mattle H Tags: Swiss Med Wkly Source Type: research

[Comment] Can China's new mental health law substantially reduce the burden of illness attributable to mental disorders?
The report by Gonghuan Yang and colleagues on the results of the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) for China provides clear evidence of the importance of mental disorders in the overall health of the nation. Mental and behavioural disorders accounted for 9·5% of all disability-adjusted life-years (DALYs) and 23·6% of all years lived with disability (YLD). Seven of the top 20 causes of YLD are mental disorders: major depressive disorder, alcohol use disorders, schizophrenia, anxiety disorders, bipolar disorder, dysthymia, and drug use disorders. (Source: LANCET)
Source: LANCET - June 6, 2013 Category: Journals (General) Authors: Michael R Phillips Tags: Comment Source Type: research

Paediatric ventricular assist devices: current achievements.
Abstract In chronic cardiomyopathy, mechanical circulatory support plays an increasingly important role for children as the shortage of suitable donor hearts increases times on the transplant waiting list. Ventricular assist devices (VADs) for adults have evolved dramatically over the last decade, both as a bridge to transplantation and for permanent support. In contrast, VADs designed for children, especially for all age groups, are still in their infancy. The Medos HIA and the Berlin Heart Excor are specially designed for children with a body surface area <1.2 m2. Increased experience with existing paediatric ...
Source: Swiss Medical Weekly - June 8, 2013 Category: Journals (General) Authors: Schweiger M, Dave H, Romanchenko O, Lemme F, Hübler M Tags: Swiss Med Wkly Source Type: research

Impact of diabetes on platelet activation in different manifestations of atherosclerosis.
CONCLUSION: Compared with healthy controls, platelets from patients with symptomatic atherosclerotic disease are activated and susceptible to PAR-1-mediated activation. Diabetes affects platelet reactivity only in patients with symptomatic CAD, while other manifestations of atherosclerosis may have an overwhelming effect on platelet reactivity that is not further enhanced by diabetes. PMID: 23740526 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - June 8, 2013 Category: Journals (General) Authors: Gremmel T, Kopp CW, Seidinger D, Koppensteiner R, Steiner S, Panzer S Tags: Swiss Med Wkly Source Type: research

[Comment] A tipping point for change: saving millions of additional lives in 2013 and beyond
In recent years we have seen gratifying progress towards Millennium Development Goals (MDGs) 4 and 5 (for child survival and maternal health, respectively). The number of child deaths is down from about 12 million in 1990 to about 7 million in 2011 and maternal deaths are down from an estimated 500 000 in 1990 to under 300 000 in 2010. (Source: LANCET)
Source: LANCET - February 1, 2013 Category: Journals (General) Authors: Goodluck Ebele Jonathan, Jens Stoltenberg Tags: Comment Source Type: research

AAD Meeting Will Cut Wide Swath Across Specialty
MIAMI BEACH (MedPage Today) -- The 71st Annual Meeting of the American Academy of Dermatology (AAD) will offer sessions on a broad range of subjects from atopic dermatitis to melanoma to reconstructive surgery and there'll be more self-assessment sessions than ever. (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - February 28, 2013 Category: Journals (General) Source Type: news

Comparison of three different sedative-anaesthetic protocols (ketamine, ketamine-medetomidine and alphaxalone) in common marmosets (Callithrix jacchus)
Background: Handling of common marmoset (Callithrix jacchus) usually requires chemical restraint. Ketamine has been associated with muscle damage in primates, while common marmosets, compared to other primates, additionally display an exceptional high sensitivity to ketamine-associated side-effects. Notably, muscle twitching movements of limbs and hands, and a marked increase in salivation are observed. We investigated two alternative intramuscular (i.m.) immobilisation protocols against ketamine (50 mg/kg; protocol 1) in a double-blind randomised crossover study in ten healthy adult common marmosets for use as a safe reli...
Source: BioMed Central - June 11, 2013 Category: Journals (General) Authors: Jaco BakkerJoost J UilenreefEva RJ PeltHerbert PM BrokEdmond J RemarqueJan AM Langermans Source Type: research

Added value of an intensive multidisciplinary functional rehabilitation programme for chronic low back pain patients.
CONCLUSION: Randomised studies are needed to confirm these results and explore the cost-effectiveness of MFRP. PMID: 23519464 [PubMed - in process] (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - May 25, 2013 Category: Journals (General) Authors: Steiner AS, Sartori M, Leal S, Kupper D, Gallice JP, Rentsch D, Cedraschi C, Genevay S Tags: Swiss Med Wkly Source Type: research

Treating the Brain Deep Down: Brain surgery for anorexia nervosa?
Nature Medicine 19, 678 (2013). doi:10.1038/nm.3223 Author: Eric J Nestler Using brain surgery, specific areas in the brain can be stimulated with electrical impulses to reversibly change their activity and alleviate symptoms related to mental illnesses. This so-called deep brain stimulation and other methodological advances that even more selectively activate specific groups of neurons can give us clues as to what neural circuitry is involved in a particular mental disorder and whether therapeutic activation of these brain areas and neurons may be effective. In 'Bedside to Bench', Eric Nestler discusses two trials...
Source: Nature Medicine - June 6, 2013 Category: Journals (General) Authors: Eric J Nestler Tags: Between Bedside and Bench Source Type: research