Laboratory Medicine 
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This page shows you the most recent publications within this specialty of the MedWorm directory.
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Upgraded vacuum arc ion source for metal ion implantation
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A. G. Nikolaev, E. M. Oks, K. P. Savkin, G. Yu. Yushkov, and I. G. Brown Vacuum arc ion sources have been made and used by a large number of research groups around the world over the past twenty years. The first generation of vacuum arc ion sources (dubbed Mevva, for metal vapor vacuum arc) was developed at Lawrence Berkeley National Laboratory in the 1980s. This paper c ... [Rev. Sci. Instrum. 83, 02A501 (2012)] published Wed Feb 1, 2012. (Source: Review of Scientific Instruments)
Source: Review of Scientific Instruments - February 3, 2012 Category: Physics Source Type: research
Heat or Acid?Email this article to a colleague.
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The question of how tropical coral reefs will respond to increasing atmospheric greenhouse gas concentrations and concomitant climate change is widely debated. Model predictions and laboratory experiments suggest that decreasing … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research
New ProductsEmail this article to a colleague.
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A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers. (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research
[Report] Affirmative Action Policies Promote Women and Do Not Harm Efficiency in the LaboratoryEmail this article to a colleague.
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Increasing the representation of competition-averse individuals does not alter overall output.Authors: Loukas Balafoutas, Matthias Sutter (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Loukas Balafoutas Source Type: research
[News of the Week] NewsmakersEmail this article to a colleague.
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This week's Newsmakers are Janet Rowley of the University of Chicago, Brian Druker of the Oregon Health & Science University, Nicholas Lydon of Blueprint Medicines, and Masato Sagawa of Intermetallics Co., winners of the Japan Prizes; Scott Doney, whose nomination to be chief scientist of the National Oceanic and Atmospheric Administration has been withdrawn by the White House; Johannes Vogel, an expert on fern genetics, who took over as director of Berlin's Natural History Museum this week; and Paul Alivisatos of Lawrence Berkeley National Laboratory, Charles Lieber of Harvard University, Jacob Bekenstein of the Hebrew Un...
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research
Scientists call for curbs on own research on deadly bird flu virusEmail this article to a colleague.
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Virus experts in the US say outbreak of genetically engineered bird flu could be worst influenza pandemic in historyA group of the leading virus experts in the US has called for new, permanent restrictions on research in the face of a new genetically engineered flu virus that could kill half the population of the world.Scientists are currently observing a 60-day moratorium on research into the bird flu virus, after two groups found a way to make it infectious through airborne transmission.An outbreak of this virus could be worse than the 1918 Spanish flu that killed tens of millions of people, warned Michael Osterholm – ...
Source: Guardian Unlimited Science - February 3, 2012 Category: Science Tags: Bird flu United States Genetics World news Science guardian.co.uk Source Type: news
Genotoxicity, cytotoxicity and toxicological evaluation of whole plant extracts of the medicinal plant Phyllanthus niruri (Phyllanthaceae).Email this article to a colleague.
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We examined the geno-, cyto- and overall toxicity of P. niruri whole plant ethanolic extract. The extract was administered as a single dose of 30 or 300 mg/kg to laboratory rats by gavage, accompanied by negative (0.9% saline) and positive (10 mg/mL N-ethyl-N-nitrosourea) controls that were injected intramuscularly 48 h after extract administration. The ratio of polychromatic (PCE)/normochromatic erythrocytes (NCE) from femur bone marrow was scored for genotoxicity. Cytotoxicity was determined using descending concentrations (0.2-0.0125 g/mL) of the extract incubated with peripheral blood mononuclear cells. Lactate dehydro...
Source: Genetics and Molecular Research - February 3, 2012 Category: Genetics & Stem Cells Authors: Asare GA, Bugyei K, Sittie A, Yahaya ES, Gyan B, Adjei S, Addo P, Wiredu EK, Adjei DN, Nyarko AK Tags: Genet Mol Res Source Type: research
Two Studies Find that Patients Want Access to their Health Records, Including Clinical Pathology Test DataEmail this article to a colleague.
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Patients are ready to ready access to their medical records; but physicians are wary Data from two studies here in the United States affirms that patients want access to their health records. Consequently, health systems are increasingly making it easier for patients to get access to prescription lists, medical laboratory test results and now even [...] (Source: Dark Daily)
Source: Dark Daily - February 3, 2012 Category: Laboratory Medicine Authors: jude Tags: Laboratory News Laboratory Pathology Annals of Internal Medicine Beth Israel Deaconess Medical Center clinical laboratory Donna Zulman Geisinger Health System Harborview Medical Center harvard medical school kaiser permanente Kenneth S Source Type: news
Twitter is harder to resist than cigarettes and alcohol, study findsEmail this article to a colleague.
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People are more likely to give in to urge to tweet or check email than other cravings, say US researchersTweeting or checking emails may be harder to resist than cigarettes and alcohol, according to researchers who tried to measure how well people could resist their desires.They even claim that while sleep and sex may be stronger urges, people are more likely to give in to longings or cravings to use social and other media.A team headed by Wilhelm Hofmann of Chicago University's Booth Business School say their experiment, using BlackBerrys, to gauge the willpower of 205 people aged between 18 and 85 in and around the Germa...
Source: Guardian Unlimited Science - February 3, 2012 Category: Science Authors: James Meikle Tags: Psychology Twitter Internet Technology Media Blogging Newspapers & magazines Digital media Smoking Society Alcohol Email Computing Science United States World news The Guardian Source Type: news
Ascites due to lupus peritonitis: a rare form of onset of systemic lupus erythematosusEmail this article to a colleague.
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O lúpus eritematoso sistêmico (LES) frequentemente cursa com serosites. Cerca de 16% dos pacientes lúpicos apresentam acometimento de pleura e pericárdio. O acometimento peritoneal, no entanto, é especialmente raro, ocorrendo clinicamente em pequeno grupo de pacientes. O presente estudo trata do caso de uma paciente de 47 anos com diagnóstico de lúpus discoide que evoluiu com manifestações sistêmicas da doença, caracterizadas por distensão e dor abdominal significativas, astenia, emagrecimento, sinais propedêuticos de ascite e diarreia aguda baixa e não invasiva. Foi realizada exaustiva investigação diagnó...
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
25-Hydroxyivitamin D3 levels in patients with systemic lupus erythematosus and its association with clinical parameters and laboratory testsEmail this article to a colleague.
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CONCLUSIONS: High prevalence of 25(OH)D insufficiency/deficiency was found in patients with SLE (57.7%), with statistically significant difference as compared with the comparison group. No association of vitamin D insufficiency/deficiency was observed with the clinical variables and laboratory tests studied. The authors emphasize the importance of determining 25(OH)D serum levels in all patients with SLE, regardless of where they live and time to disease diagnosis (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Prediction of environmental concentrations of glucocorticoids: The River Thames, UK, as an example.Email this article to a colleague.
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Abstract
Synthetic glucocorticoids (GCs) are consumed in large amounts as anti-inflammatory and immunosuppressive drugs worldwide. Based on what has been learnt from studies of other human pharmaceuticals, they are likely to be present in the aquatic environment. However, to date, information on the environmental concentrations of GCs is very limited. The situation is complicated by the fact that a considerable number of GCs are in everyday use in most developed countries. Hence, obtaining a full picture of GC concentrations in the aquatic environment using the traditional analytical chemistry approach would be tim...
Source: Environment International - February 3, 2012 Category: Environmental Health Authors: Kugathas S, Williams RJ, Sumpter JP Tags: Environ Int Source Type: research
Response to: Lack of intra-laboratory reproducibility in using Platelia Aspergillus enzyme immunoassay test for detection of Aspergillus galactomannan antigenEmail this article to a colleague.
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Bizzini A, Marchetti O, Meylan P (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
New international standards to aid data sharingEmail this article to a colleague.
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Led by researchers at University of Oxford (UK) and the Harvard Stem Cell Institute (HSCI) at Harvard University, (USA), more than 50 collaborators at over 30 scientific organizations around the globe have agreed on a common standard for integrating biological data sets. This will make it possible to consistently describe the enormous and radically different databases that are compiled in the biosciences in fields ranging from genetics to stem cell science, to environmental studies.This collaborative effort provides a way for scientists in widely disparate life science fields to co-ordinate each other's findings by allowin...
Source: MEDEV News - February 3, 2012 Category: Universities & Medical Training Source Type: news
BioConference Live Announces 2012 Virtual Event ScheduleEmail this article to a colleague.
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Free Virtual Events at http://www.BioConferenceLive.com focusing on the Clinical Diagnostics, Life Sciences, and Laboratory Animal Sciences Community(PRWeb January 31, 2012)Read the full story at http://www.prweb.com/releases/2012/1/prweb9146126.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 3, 2012 Category: Pharmaceuticals Source Type: news
Collective actionEmail this article to a colleague.
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(European Molecular Biology Laboratory) Genetic switches called enhancers and the molecules that activate them can be used to draw a cell's family tree, EMBL scientists have found. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 3, 2012 Category: Biology Source Type: news
Serum osmolarity as an outcome predictor in hospital emergency medical admissions.Email this article to a colleague.
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CONCLUSION: Admission osmolarity, a simple calculation, is associated with the risk of mortality in acutely ill medical patients; deviations outside the normal range are relevant. A useful clinical predictive algorithm requires the incorporation of additional predictors.
PMID: 22284254 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - February 2, 2012 Category: Internal Medicine Authors: Nicholson T, Bennett K, Silke B Tags: Eur J Intern Med Source Type: research
How Red Wine's Resveratrol Confers Health BenefitsEmail this article to a colleague.
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Scientists have found out why resveratrol, a chemical naturally found in red wine, grapes, and some other fruit and vegetables, has health benefits, according to an article published in the journal Cell, February 3rd issue. The researchers, from the Laboratory of Obesity and Aging Research at the NIH's National Heart, Lung, and Blood Institute, explain that resveratrol inhibits PDEs (phosphodiesterases), proteins (enzymes) that play a crucial role in cell energy regulation. Resveratrol's molecular formula is C14H12O3... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 2, 2012 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news
For Military Researchers, the Butterfly is the Ultimate Drone [Video]Email this article to a colleague.
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Butterflies are not merely beautiful. They use a complex pattern of rapid wing flapping and body deformation to execute impressive aerial acrobatics. This ability has not escaped the U.S. military, which is turning to these insects for ideas on how to create ever-smaller drone aircraft to execute reconnaissance, search-and-rescue and environmental monitoring missions. [View a slide show featuring different drones used by the U.S. military.] The Air Force Research Laboratory at Wright-Patterson Air Force Base in Ohio is testing drones less than 60 centimeters long roughly the wingspan of an Atlantic Puffin with the hope the...
Source: Scientific American - Official RSS Feed - February 2, 2012 Category: Science Tags: Evolution,Technology,More Science Source Type: research
Should we really fear 'new flesh-eating bacteria'?Email this article to a colleague.
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Conclusion
This interesting study helps explain why healthcare-acquired MRSA infections are rarely found in healthy individuals. It found that expression of a gene that produces one of the proteins responsible for MRSA’s antibiotic resistance caused it to be less toxic. It also showed that typical community-acquired MRSA strains express less of this antibiotic-resistance protein, but are more toxic.
However, this intriguing lab study did not investigate the transmission, effects or number of cases of community-acquired MRSA in the UK, discussion of which formed the majority of the news reports. On this basis, the researc...
Source: NHS News Feed - February 2, 2012 Category: Consumer Health News Tags: Medical practice Source Type: news
UCLA researchers identify peptide that inhibits replication of hepatitis C virusEmail this article to a colleague.
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Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks the viral replication that can lead to liver cancer and cirrhosis.
The finding by Dr. Samuel French, a UCLA assistant professor of pathology and senior author of the research, builds on previous work by French's laboratory that identified two cellular proteins that are important factors in hepatitis C virus infection.
In that earlier research, French and his team set out to identify the cellular factors involved in hepatitis C replication. Using mass spectro...
Source: UCLA Newsroom: Health Sciences - February 2, 2012 Category: Universities & Medical Training Source Type: news
In United Kingdom, Clinical Pathology Laboratories Must Transform to Help Primary Care Physicians Achieve Improved Patient OutcomesEmail this article to a colleague.
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Frontiers in Laboratory Medicine (FiLM) attracted another record crowd of clinical laboratory managers and pathologists DATELINE—BIRMINGHAM, ENGLAND: Healthcare in the United Kingdom is undergoing a host of reforms. Consequently, medical laboratories in this country are scrambling to evolve in ways that allow them to serve the new line-up of primary care trusts and hospital trusts, [...] (Source: Dark Daily)
Source: Dark Daily - February 2, 2012 Category: Laboratory Medicine Authors: jude Tags: Laboratory News Laboratory Pathology Management & Operations News From Dark Daily clinical laboratory commissioning FiLM Frontiers in Laboratory Medicine Hemai Desai James Crawford MD PhD medical laboratory national health service Source Type: news
Could Simple Experiments Reveal the Quantum Nature of Spacetime?Email this article to a colleague.
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Conventional wisdom has it that putting the words quantum gravity and experiment in the same sentence is like bringing matter into contact with antimatter. All you get is a big explosion; the two just don t go together. The distinctively quantum features of gravity only show up in extreme settings such as the belly of a black hole or the nascent universe, over distances too small and energies too large to reproduce in any laboratory. Even alien civilizations that command the energy resources of a whole galaxy probably couldn t do it.Physicists have never been much for conventional wisdom, though, and the dream of studying ...
Source: Scientific American - Official RSS Feed - February 2, 2012 Category: Science Tags: More Science,Space Source Type: research
Hyperconnectivity In Brain's Hearing Center Caused By Gene Mutation In AutismEmail this article to a colleague.
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New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound. The study has found that when a suspected autism gene called PTEN is deleted from auditory cortical neurons - the main workhorses of the brain's sound-processing center - the signals that these neurons receive from local as well as long-distance sources are strengthened beyond normal levels... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 2, 2012 Category: Consumer Health News Tags: Autism Source Type: news
Decisions on HEFCE funding for higher education 2012-13Email this article to a colleague.
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The Higher Education Funding Council for England (HEFCE) announced its funding decisions for higher education in England following the annual grant letter (Note 1) from the Department for Business Innovation and Skills (BIS) and subsequent decisions by the HEFCE Board. This announcement covers HEFCE funding for the academic year 2012-13 (Note 2).
The overall level of government support for teaching in universities and colleges is set to increase over the next few years as a result of higher tuition fee loans under the Government’s new finance arrangements for higher education. HEFCE’s grant will reduce accordin...
Source: MEDEV News - February 2, 2012 Category: Universities & Medical Training Source Type: news
Biomechanical Evaluation of a Novel Reverse Coracoacromial Ligament Reconstruction for Acromioclavicular Joint SeparationEmail this article to a colleague.
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Conclusion: Addition of either reverse CA transfer or intramedullary graft demonstrates improved AP restraint and provides similar SI stability compared with isolated CC reconstruction.
Clinical Relevance: Reverse CA ligament transfer may be a reasonable alternative to a free tendon graft to augment AP restraint in AC reconstruction. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - February 2, 2012 Category: Sports Medicine Authors: Shu, B., Johnston, T., Lindsey, D. P., McAdams, T. R. Tags: Shoulder, Biomechanics research-article Source Type: research
New Suture Method for Radial Tears of the Meniscus: Biomechanical Analysis of Cross-Suture and Double Horizontal Suture Techniques Using Cyclic Load TestingEmail this article to a colleague.
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Conclusion: Our cross-suture technique significantly improved the structural properties of the repaired complete radial meniscal tears.
Clinical Relevance: The cross-suture technique for repair of radial meniscal tears provides high stability and could be a promising solution in young and in active patients. (Source: The American Journal of Sports Medicine)
Source: The American Journal of Sports Medicine - February 2, 2012 Category: Sports Medicine Authors: Matsubara, H., Okazaki, K., Izawa, T., Tashiro, Y., Matsuda, S., Nishimura, T., Nakanishi, Y., Kawamura, H., Iwamoto, Y. Tags: Injury, Meniscus, Biomechanics research-article Source Type: research
The Effect of a Hill-Sachs Defect on Glenohumeral Translations, In Situ Capsular Forces, and Bony Contact ForcesEmail this article to a colleague.
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Conclusion: We believe that the stabilizing function of the intact capsule was the primary contributor to the finding of only small increases of anterior translation, capsule forces, and bony contact forces observed with a 25% Hill-Sachs defect in response to an anterior load.
Clinical Relevance: These findings imply that a 25% Hill-Sachs defect in isolation may not be responsible for recurrent instability if the function of the capsule is restored to the intact state and that the presence of the Hill-Sachs defect may be a marker for significant concomitant injury to the anterior glenoid rim. However, the small cha...
Source: The American Journal of Sports Medicine - February 2, 2012 Category: Sports Medicine Authors: Sekiya, J. K., Jolly, J., Debski, R. E. Tags: Shoulder, Biomechanics research-article Source Type: research
Relationship Between Proximal Femoral and Acetabular Alignment in Normal Hip Joints Using 3-Dimensional Computed TomographyEmail this article to a colleague.
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Conclusion: This study demonstrates that a correlation exists between multiple proximal femoral and acetabular angles in normal hip joints. These findings support the hypothesis that a complementary developmental relationship occurs between the femoral head and acetabulum.
Clinical Relevance: The results of this study suggest that, in some patients, what is thought to be pathological acetabular retroversion may actually be normal anatomy with a compensated femoral version. Investigating the relationship between these angles in patients with the signs and symptoms of pincer-type femoroacetabular impingement may alte...
Source: The American Journal of Sports Medicine - February 2, 2012 Category: Sports Medicine Authors: Buller, L. T., Rosneck, J., Monaco, F. M., Butler, R., Smith, T., Barsoum, W. K. Tags: Imaging Studies, Hip/groin research-article Source Type: research
Force Measurements in the Medial Meniscus Posterior Horn Attachment: Effects of Anterior Cruciate Ligament RemovalEmail this article to a colleague.
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Conclusion: Applied anterior tibial force and external tibial torque were loading modes that produced relatively high PHA forces, presumably by impingement of the medial femoral condyle against the medial meniscus posterior horn rim. Under joint load, an ACL-deficient knee was particularly susceptible to PHA injury from applied anterior tibial force.
Clinical Relevance: Because tensile forces developed in the PHA are also borne by meniscus tissue near the attachment site, loading mechanisms that produce high PHA forces could also produce complete or partial radial tears near the posterior horn, a relatively common ...
Source: The American Journal of Sports Medicine - February 2, 2012 Category: Sports Medicine Authors: Markolf, K. L., Jackson, S. R., McAllister, D. R. Tags: Reconstruction, Knee, Biomechanics research-article Source Type: research
Biomechanical and Histological Evaluations of the Doubled Semitendinosus Tendon Autograft After Anterior Cruciate Ligament Reconstruction in SheepEmail this article to a colleague.
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Conclusion: The sheep ACL reconstruction model showed predominant intrinsic fibroblast necrosis in the tendon autograft until 12 weeks. Although the structural properties of the femur-graft-tibia complex gradually improved, they were not completely restored to the femur-ACL-tibia complex level even at 52 weeks.
Clinical Relevance: Remodeling of the semitendinosus tendon autograft after ACL reconstruction is not different from that of the bone-tendon-bone graft. This study has suggested that vigorous activity should not be permitted for patients in the early periods after ACL reconstruction using semitendinosus tend...
Source: The American Journal of Sports Medicine - February 2, 2012 Category: Sports Medicine Authors: Kondo, E., Yasuda, K., Katsura, T., Hayashi, R., Kotani, Y., Tohyama, H. Tags: Reconstruction, Animal studies, Graft fixation research-article Source Type: research
Deregulation of apoptosis-related genes is associated with PRV1 overexpression and JAK2 V617F allele burden in Essential Thrombocythemia and MyelofibrosisEmail this article to a colleague.
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Conclusions:
Our results suggest the participation of intrinsic apoptosis pathway in the MPN physiopathology. In addition, PRV1 and JAK2 V617F allele burden were linked to deregulation of the apoptotic machinery. (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - February 2, 2012 Category: Hematology Authors: Raquel TognonElainy GasparottoRenata NevesNatalia NunesAline FerreiraPatricia PalmaSimone KashimaDimas CovasMary SantanaElizabeth SoutoMaria Aparecida ZanichelliBelinda SimoesAna Maria SouzaFabiola Castro Source Type: research
ORNL, partners earn FLC honor for cookstove technologyEmail this article to a colleague.
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(DOE/Oak Ridge National Laboratory) Envirofit International, the Department of Energy's Oak Ridge National Laboratory and Colorado State University have won a Federal Laboratory Consortium award for excellence in technology transfer for a clean-burning cookstove designed for the developing world. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 2, 2012 Category: Global & Universal Source Type: news
NASA mission returns first video from moon's far sideEmail this article to a colleague.
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A camera aboard one of NASA's twin Gravity Recovery And Interior Laboratory (GRAIL) lunar spacecraft has returned its first unique view of the far side of the moon. MoonKAM, or Moon Knowledge Acquired by Middle school students, will be used by students nationwide to select lunar images for study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 1, 2012 Category: Science Source Type: news
Cross-sectional area of psoas major muscle and hip flexion strength in youth soccer playersEmail this article to a colleague.
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This study aimed to clarify the differences in the cross-sectional area (CSA) of the psoas major (PM) muscle and hip flexion
force (HFF) of the right (dominant) side between adolescent male soccer players and age-matched non-athletes. PM CSA at L4–L5
and HFF at 1.05 rad/s were determined in 22 early (12.8–13.6 years) and 27 late (16.1–17.9 years) adolescent soccer players
and 11 early (12.6–13.5 years) and 20 late (16.0–17.7 years) adolescent non-athletes. Fat-free mass (FFM) was greater in late
adolescent soccer players than in late adolescent non-athletes, but was similar between th...
Source: European Journal of Applied Physiology - February 1, 2012 Category: Physiology Tags: European Journal of Applied Physiology Source Type: research
A transgenic Marc-145 cell line of piggyBac transposon-derived targeting shRNA interference against porcine reproductive and respiratory syndrome virusEmail this article to a colleague.
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In this study, we designed 5 of the small hairpin RNAs (shRNAs) targeting the GP5 and M gene of PRRSV
respectively, and investigated their inhibition to the production of PRRSV. The highest activity displayed in shRNAs of the
ORF6e sequence (nts 261-279), which the inhibition rate reached was 99.09%. The result suggests that RNAi technology might
serve as a potential molecular strategy for PRRSV therapy. Furthermore, the transgenic Marc-145 cell line of piggyBac transposon-derived targeting shRNA interference against PRRS virus was established. It presented stable inhibition to
the replication and amplification of PRRS...
Source: Veterinary Research Communications - February 1, 2012 Category: Veterinary Research Tags: Veterinary Research Communications Source Type: research
Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell linesEmail this article to a colleague.
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This study suggests different antiviral
functions of polyvalent IVIG and confirms their potential to inhibit a CMV infection in vitro, with profound differences between
the hereby used IVIG products.
Content Type Journal ArticleCategory Original PaperPages 1-10DOI 10.1007/s00430-012-0229-2Authors
K. Frenzel, Institute of Medical Virology, Helmut-Ruska-Haus, Charité University Medicine, Charitéplatz 1, 10117 Berlin, GermanyS. Ganepola, Department of Haematology, Oncology and Transfusion Medicine, Charité University Medicine, Berlin, GermanyD. Michel, Institute of Virology, University Hospital Ulm, Ulm, GermanyE....
Source: Medical Microbiology and Immunology - February 1, 2012 Category: Microbiology Tags: Medical Microbiology and Immunology Source Type: research
In Massachusetts, Blues Ink Pact with Partners HealthCare to Implement Alternative Quality Contract with Global PaymentEmail this article to a colleague.
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Early evidence is that the AQC arrangement encourages providers to more carefully utilize ancillary services, including clinical laboratory and pathology testing Much attention is being given to the new healthcare payment models being introduced by the Medicare program during 2012. However, quietly—and with much less publicity—private health plans are deploying innovative, value-based payment models. These [...] (Source: Dark Daily)
Source: Dark Daily - February 1, 2012 Category: Laboratory Medicine Authors: jude Tags: Coding, Billing, and Collections Compliance, Legal, and Malpractice Laboratory News Laboratory Operations Laboratory Pathology Alternative Quality Contract Andrew Dreyfus AQC BCBSMA blue cross blue shield of massachusetts Brandeis Univ Source Type: news
Tackling the challenge of setting up a 3D lab: Part 1Email this article to a colleague.
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In the first of a two-part series on how to set up a 3D laboratory, AuntMinnie.com (more) (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 1, 2012 Category: Radiology Source Type: news
Current SEM techniques for de‐ and re‐construction of centromeres to determine 3D CENH3 distribution in barley mitotic chromosomesEmail this article to a colleague.
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SummaryCombined light microscopic (LM) and field emission scanning electron microscopic (FESEM) techniques with FluoroNanogold labelling allowed quantification and high resolution analysis of 3D distribution of the centromere‐specific histone H3 variant CENH3 in barley mitotic chromosomes. Chromosomes were investigated with fluorescence LM, conventional FESEM, low‐voltage FESEM and combined FIB/FESEM techniques for unprecedented comprehensive analysis to determine chromatin distribution patterns in the centromere. Using data from FIB/FESEM sectioning of centromeric regions of chromosomes, it was possible to render 3D r...
Source: Journal of Microscopy - February 1, 2012 Category: Laboratory Medicine Authors: E. SCHROEDER‐REITERM. SANEIA. HOUBENG. WANNER Source Type: research
Effects of anti‐CD3 monoclonal antibody in salivary glands of spontaneously diabetic miceEmail this article to a colleague.
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Conclusion: These results indicate that immunotherapy contributed to reestablishment of tissue damaged by the hyperglycemic condition, demonstrating that the immunomodulation plays an important role in the recovery of salivary glands. Microsc. Res. Tech., 2012. © 2012 Wiley Periodicals, Inc. (Source: Microscopy Research and Technique)
Source: Microscopy Research and Technique - February 1, 2012 Category: Laboratory Medicine Authors: Hugo Tadeu MetidieriRafael Dias MancioÉber Emanuel MayoralFernanda Alvarez RojasLuis Antonio PeroniAlan Telles FerriEdmir Américo LourençoEduardo José Caldeira Tags: Research Article Source Type: research
In vivo remineralization of acid‐etched enamel in non‐brushing areas as influenced by fluoridated orthodontic adhesive and toothpasteEmail this article to a colleague.
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This study aimed to evaluate the in vivo remineralization of acid‐etched enamel in non‐brushing areas as influenced by fluoridated orthodontic adhesive and toothpaste. One hundred and twenty teeth from 30 volunteers were selected. The teeth were assigned to four treatments: no treatment (negative control); 37% phosphoric acid‐etching (PAE) (positive control); PAE + resin‐modified glass ionomer cement (RMGIC); and, PAE + composite resin. Patients brushed teeth with fluoridated (n = 15) or non‐fluoridated (n = 15) toothpastes, so that etched enamel was protected with screens and it was not in contact with the brush...
Source: Microscopy Research and Technique - February 1, 2012 Category: Laboratory Medicine Authors: Otávio José Praxedes‐NetoBoniek Castillo Dutra BorgesCícero Florêncio‐FilhoArthur Costa Rodrigues FariasJohn DrennanKenio Costa De Lima Tags: Research Article Source Type: research
Effect of disinfectant solutions on gutta‐percha and resilon conesEmail this article to a colleague.
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In conclusion, 5.25% NaOCl and MTAD are associated with local changes in surface roughness of gutta‐percha cones. No change was observed when 2% CHX was used. The use of all tested solutions did not produce any changes on Resilon surface. Microsc. Res. Tech., 2012. © 2012 Wiley Periodicals, Inc. (Source: Microscopy Research and Technique)
Source: Microscopy Research and Technique - February 1, 2012 Category: Laboratory Medicine Authors: Maíra PradoHeloisa GusmanBrenda P.F.A. GomesRenata A. Simão Tags: Research Article Source Type: research
Expression of TRPV4 in the zebrafish retina during developmentEmail this article to a colleague.
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AbstractThe transient receptor potential (TRP) channels are involved in sensing mechanical/physical stimuli such as temperature, light, pressure, as well as chemical stimuli. Some TRP channels are present in the vertebrate retina, and the occurrence of the multifunctional channel TRP vanilloid 4 (TRPV4) has been reported in adult zebrafish. Here, we investigate the expression and distribution of TRPV4 in the retina of zebrafish during development using polymerase chain reaction (PCR), Western blot, and immunohistochemistry from 3 days post fertilization (dpf) until 100 dpf. TRPV4 was detected at the mRNA and protein levels...
Source: Microscopy Research and Technique - February 1, 2012 Category: Laboratory Medicine Authors: C. Sánchez‐ramosM.C. GuerreraC. Bonnin‐AriasM.G. CalaviaR. LauràA. GermanàJ.A. Vega Tags: Research Article Source Type: research
Gross and microscopic observations on the lingual structure of the franciscana (Pontoporia blainvillei — gervais and d'orbigny, 1844)Email this article to a colleague.
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AbstractIn most anatomical studies developed with mammals, the tongue is described as highly differentiated among different species. However, studies on the tongue of aquatic mammals are still limited as compared to those on terrestrial mammals. The aim of this study was to describe the tongue morphology of the Franciscana dolphin (Pontoporia blainvillei) using macroscopic observations, light, and scanning electron microscopy. Microscopically, the dorsal surface was covered by a keratinized stratified epithelium. Salivary gland acini were found on the middle and caudal third of the tongue. The dorsal surface was totally co...
Source: Microscopy Research and Technique - February 1, 2012 Category: Laboratory Medicine Authors: J.P. GuimarãesR.B. MariJ. MarigoF.C.W. RosasI. Watanabe Tags: Research Article Source Type: research
Influences of the insertion method in glass ionomer cement porosityEmail this article to a colleague.
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CONCLUSION: Although the use of LCS has not decreased the porosity of the material, this insertion method is easy, accessible, and low cost, which makes it a viable alternative of use in the ART technique and in others bucal health programs. Microsc. Res. Tech., 2012. © 2012 Wiley Periodicals, Inc. (Source: Microscopy Research and Technique)
Source: Microscopy Research and Technique - February 1, 2012 Category: Laboratory Medicine Authors: Margareth Da MataLourdes Santos‐PintoAngela Cristina Cilense Zuanon Tags: Research Article Source Type: research
Evaluation of Levetiracetam as Adjunctive Treatment for Refractory Canine Epilepsy: A Randomized, Placebo‐Controlled, Crossover TrialEmail this article to a colleague.
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Conclusions and Clinical ImportanceAdjunctive treatment with LEV appears safe in epileptic dogs. Efficacy of LEV over placebo was not demonstrated, although the power of the study was limited. Further evaluation of LEV as treatment for epilepsy in dogs is warranted. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - February 1, 2012 Category: Veterinary Research Authors: K.R. MuñanaW.B. ThomasK.D. InzanaJ.A. Nettifee‐OsborneK.J. McLucasN.J. OlbyC.J. MarianiP.J. Early Tags: Standard Article Source Type: research
Encourage lab testing to confront conditions earlyEmail this article to a colleague.
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According to experts, improving accessibility to laboratory tests and results improves patient
engagement in their health and could have significant cost saving implications for managed care. (Source: Managed Healthcare Executive Magazine Online)
Source: Managed Healthcare Executive Magazine Online - February 1, 2012 Category: Health Management Source Type: news
Risk factors for patient‐reported medical errors in eleven countriesEmail this article to a colleague.
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Conclusions Safety remains a global challenge affecting many patients throughout the world. Large variability exists in the frequency of patient‐reported error across countries. To learn from others’ errors is not only essential within countries but may also prove a promising strategy internationally. (Source: Health Expectations)
Source: Health Expectations - February 1, 2012 Category: Health Management Authors: David L. B. Schwappach Source Type: research
Analytical quality of assays and comparison of procedures for the sweat test.Email this article to a colleague.
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In conclusion, comparison of methods highlighted that the less the sweat test is automatically controlled, the more the operator influence on results quality is important. Our study supports that sweat test result <50 mmol/L NaCl Eq is unlikely with CF diagnosis in absence of clinical arguments.
PMID: 22294136 [PubMed - as supplied by publisher] (Source: Annales de Biologie Clinique)
Source: Annales de Biologie Clinique - February 1, 2012 Category: Biochemistry Authors: Nguyen-Khoa T, Borgard JP, Marchand M, Sitruk-Khalfon D, Feuillet MN, Feldmann D, Vassault A, Rota M Tags: Ann Biol Clin (Paris) Source Type: research
