Laboratory Medicine 
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This page shows you the most recent publications within this specialty of the MedWorm directory.
79861 records returned
Practical Laboratory Aspects of Cystic Fibrosis Microbiology: an Update, Part I
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This article provides an update of the major CF pathogens and offers a practical laboratory guide that addresses some of the issues encountered with these cultures. Part I of this two-part article reviews the new and most current information gathered from the literature since 2006 with respect to Pseudomonas aeruginosa, Burkholderia cepacia complex, and other glucose non-fermenting gram-negative rods. Part II of this article will complete the review of the key organisms associated with CF infections, including Staphylococcus aureus, nontuberculous mycobacteria, and fungi. Issues regarding susceptibility testing will also b...
Source: Clinical Microbiology Newsletter - February 6, 2012 Category: Microbiology Authors: Deanna L. Kiska, Scott W. Riddell Source Type: news
Examination of Factors Affecting Adverse Reactions and Dosage Reduction in UGT1A1 Genotyped Patients: A Retrospective Survey of Irinotecan.Email this article to a colleague.
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Abstract
Our aim was to clarify the side effects of irinotecan which occurred in patients admitted to Showa University Hospital to investigate whether the UGT1A1 genetic polymorphism status was reflected in the discontinuation or dose reduction of irinotecan. We retrospectively investigated UGT1A1 genetic polymorphisms, irinotecan dosage, dose discontinuance or reduction, and laboratory results from May 1 2009 to April 30 2010. The analysis of UGT1A1 genetic polymorphisms in 23 patients showed that frequencies of the UGT1A1*6 and UGT1A1*28 polymorphisms were 35% (eight patients) and 22% (five patients), respectivel...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - February 6, 2012 Category: Drugs & Pharmacology Authors: Okazaki K, Watanabe T, Saito I, Murayama J Tags: Yakugaku Zasshi Source Type: research
Effect of Land Application of Phosphorus-Saturated Gypsum on Soil Phosphorus in a Laboratory IncubationEmail this article to a colleague.
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The objective of this study was to evaluate what effect soil amendment with gypsum would have on soil P concentrations and forms in a laboratory incubation experiment. Gypsum was saturated at two levels with P, and applied to a silt loam and a sandy loam at two rates. The treated soils were incubated in the laboratory at 25°C, and samples were collected on eight dates between 0 and 183 days after amendment. Spent gypsum application did not significantly increase soil water-extractable or Mehlich 3 P when applied at typical agronomic rates. This appears to be a viable strategy to remove P from agricultural drainage wat...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research
Clinical and Forensic Signs Related to Cocaine Abuse. - Dinis-Oliveira RJ, Carvalho F, Duarte JA, Proença JB, Santos A, Magalhães T.Email this article to a colleague.
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Good laboratory practice in toxicological analysis requires pre-analytical steps for collection of detailed information related to the suspected poisoning episodes, including biological and non-biological circumstantial evidences, which should be carefully... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 6, 2012 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
When Recruiting and Training Generation Y to Work in Medical Laboratories, U.S.A and U.K. Face Same ChallengesEmail this article to a colleague.
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DATELINE—BIRMINGHAM, ENGLAND: Workforce issues in medical laboratories received special attention here at the 10th Annual Frontiers in Laboratory Medicine (FiLM) conference that ended last week. Probably the major concern going forward is how to attract, train, and sustain adequate numbers in the medical laboratory workforce. Two speakers addressed medical laboratory workforce issues at a strategic [...] (Source: Dark Daily)
Source: Dark Daily - February 6, 2012 Category: Laboratory Medicine Authors: jude Tags: Laboratory News Laboratory Operations Laboratory Pathology News From Dark Daily american society for clinical laboratory science ASCLS Elissa Passiment FiLM Frontiers in Laboratory Medicine Generation Y medical laboratory Millennials Source Type: news
Bill Gates backs climate scientists lobbying for large-scale geoengineeringEmail this article to a colleague.
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Other wealthy individuals have also funded a series of reports into the future use of technologies to geoengineer the climate• What is geo-engineering?• Scientists criticise handling of geoengineering pilot projectA small group of leading climate scientists, financially supported by billionaires including Bill Gates, are lobbying governments and international bodies to back experiments into manipulating the climate on a global scale to avoid catastrophic climate change.The scientists, who advocate geoengineering methods such as spraying millions of tonnes of reflective particles of sulphur dioxide 30 miles above earth...
Source: Guardian Unlimited Science - February 6, 2012 Category: Science Authors: John Vidal Tags: Geoengineering Climate change Environment Science Bill Gates Technology World news The Guardian Source Type: news
Mothers' and Fathers' Parenting Quality and Toddlers' Interactive Behaviours in Dyadic and Triadic Family ContextsEmail this article to a colleague.
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This study adds unique insights to the differences and similarities of parent–child dyadic and triadic interactions during toddlerhood. Copyright © 2012 John Wiley & Sons, Ltd. (Source: Infant and Child Development)
Source: Infant and Child Development - February 6, 2012 Category: Child Development Authors: Kyong‐Ah KwonHyun‐Joo JeonJoellen T LewsaderJames Elicker Tags: Research Article Source Type: research
E. Coli O157:H7 Population Reduction from Alfalfa Seeds with Malic Acid and Thiamine Dilauryl Sulfate and Quality Evaluation of the Resulting SproutsEmail this article to a colleague.
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The objectives of this research were to examine the efficacy of malic acid (MA) and thiamine dilauryl sulfate (TDS) combined treatments on the inactivation of E. coli O157:H7 on alfalfa seeds, to study the growth of the remaining E. coli cells during sprouting, and to evaluate the sprout quality. When 10 g of inoculated alfalfa seeds were washed in a 10% MA‐1% TDS solution, a complete elimination of E. coli was achieved. The same result was observed by washing the seeds in a 20000 ppm Ca(OCl)2 solution. However, when the seed size was increased to 50 g while maintaining the same seed‐to‐sanitizer ratio, both the MA +...
Source: Journal of Food Science - February 6, 2012 Category: Food Science Authors: Lilia FransiscaHee Kyung ParkHao Feng Source Type: research
Tolerability and efficacy of the intestinal phosphate binder Lantharenol(R) in catsEmail this article to a colleague.
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Conclusions:
The feed additive was well accepted and tolerated by all cats. Therefore, Lantharenol(R) presents a well tolerated and efficacious option to individually tailor restriction of dietary phosphorus as indicated for instance in feline chronic kidney disease. (Source: BMC Veterinary Research - Latest articles)
Source: BMC Veterinary Research - Latest articles - February 6, 2012 Category: Veterinary Research Authors: Bernard SchmidtUte DribuschPeet DelportJurgen GroppF van der Staay Source Type: research
Zolmitriptan-induced acute myocardial infarction.Email this article to a colleague.
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We present the case of a 45 year-old woman with a history of migraine with visual aura since the age of 20. She had no history of diabetes mellitus, hypertension, smoking or any other risk factors for cardiovascular events before she was admitted to our emergency room with typical chest pain. An electrocardiogram revealed anterior myocardial infarction following her monthly dose of oral zolmitriptan. Catherization revealed a normal coronary arterial system. The laboratory indices for cardiac risk were within normal ranges. The patient was advised to avoid triptans permanently on being discharged. (Cardiol J 2012; 19, 1: 76...
Source: Cardiology Journal - February 5, 2012 Category: Cardiology Authors: Kocaoglu I, Gökaslan S, Karagöz A, Sahin D, Ucar O, Aydogdu S Tags: Cardiol J Source Type: research
Two Studies Find that Patients Want Access to their Health Records, Including Clinical Pathology Test DataEmail this article to a colleague.
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Source: Dark Daily Content: “Data from two studies here in the United States affirms that patients want access to their health records. Consequently, health systems are increasingly making it easier for patients to get access to prescription lists, medical laboratory test results and now even doctors’ notes.
These findings are important for clinical laboratories and anatomic [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)
Source: ICMCC: The International Council on Medical and Care Compunetics - February 5, 2012 Category: Information Technology Authors: Lodewijk Tags: News RA News Record Access lab results Notes Patient Source Type: news
Does A Lab-Measured Compassionate Brain Fare Well In Real Life?Email this article to a colleague.
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A new series of studies is being launched by the University of Wisconsin-Madison, exploring insight knowledge on how laboratory measures of moral qualities, such as compassion, relate to real-life behavior. Founder of the UW's Center for Investigating Healthy Minds (CIHM), Dr. Richard J. Davidson at the Waisman Center, was awarded a three-year, $1.7 million grant from the John Templeton Foundation for developing laboratory and real life measures of moral qualities, such as compassion and selflessness... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 4, 2012 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news
Upgraded vacuum arc ion source for metal ion implantationEmail this article to a colleague.
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A. G. Nikolaev, E. M. Oks, K. P. Savkin, G. Yu. Yushkov, and I. G. Brown Vacuum arc ion sources have been made and used by a large number of research groups around the world over the past twenty years. The first generation of vacuum arc ion sources (dubbed Mevva, for metal vapor vacuum arc) was developed at Lawrence Berkeley National Laboratory in the 1980s. This paper c ... [Rev. Sci. Instrum. 83, 02A501 (2012)] published Wed Feb 1, 2012. (Source: Review of Scientific Instruments)
Source: Review of Scientific Instruments - February 3, 2012 Category: Physics Source Type: research
Heat or Acid?Email this article to a colleague.
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The question of how tropical coral reefs will respond to increasing atmospheric greenhouse gas concentrations and concomitant climate change is widely debated. Model predictions and laboratory experiments suggest that decreasing … [Read more] (Source: This Week in Science)
Source: This Week in Science - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research
New ProductsEmail this article to a colleague.
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A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers. (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research
[Report] Affirmative Action Policies Promote Women and Do Not Harm Efficiency in the LaboratoryEmail this article to a colleague.
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Increasing the representation of competition-averse individuals does not alter overall output.Authors: Loukas Balafoutas, Matthias Sutter (Source: Science: Current Issue)
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Loukas Balafoutas Source Type: research
[News of the Week] NewsmakersEmail this article to a colleague.
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This week's Newsmakers are Janet Rowley of the University of Chicago, Brian Druker of the Oregon Health & Science University, Nicholas Lydon of Blueprint Medicines, and Masato Sagawa of Intermetallics Co., winners of the Japan Prizes; Scott Doney, whose nomination to be chief scientist of the National Oceanic and Atmospheric Administration has been withdrawn by the White House; Johannes Vogel, an expert on fern genetics, who took over as director of Berlin's Natural History Museum this week; and Paul Alivisatos of Lawrence Berkeley National Laboratory, Charles Lieber of Harvard University, Jacob Bekenstein of the Hebrew Un...
Source: Science: Current Issue - February 3, 2012 Category: Science Authors: Stewart Wills (mailto:swills at aaas.org) Source Type: research
Scientists call for curbs on own research on deadly bird flu virusEmail this article to a colleague.
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Virus experts in the US say outbreak of genetically engineered bird flu could be worst influenza pandemic in historyA group of the leading virus experts in the US has called for new, permanent restrictions on research in the face of a new genetically engineered flu virus that could kill half the population of the world.Scientists are currently observing a 60-day moratorium on research into the bird flu virus, after two groups found a way to make it infectious through airborne transmission.An outbreak of this virus could be worse than the 1918 Spanish flu that killed tens of millions of people, warned Michael Osterholm – ...
Source: Guardian Unlimited Science - February 3, 2012 Category: Science Tags: Bird flu United States Genetics World news Science guardian.co.uk Source Type: news
Friday Report from GU ASCO; BiomarkersEmail this article to a colleague.
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Ulka Vaishampayan, MD writes: Biomarkers represent the future of renal cancer therapeutics. With six new targeted-therapy agents receiving U.S. Food and Drug Administration approvals, and many more maturing toward becoming established therapies, optimization of these treatments has become a dire need of the moment. Current prognostic information is predominantly reliant on patient and tumor characteristics and is derived from basic clinical history, physical examination, and laboratory tests.02/04/2012 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 3, 2012 Category: Cancer & Oncology Source Type: news
Could a Blood Test Help Spot Depression?Email this article to a colleague.
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Small study suggests 'biomarker' levels might help support a diagnosis, but more research needed
Source: HealthDay
Related MedlinePlus Pages: Depression, Laboratory Tests (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 3, 2012 Category: Consumer Health News Source Type: news
Genotoxicity, cytotoxicity and toxicological evaluation of whole plant extracts of the medicinal plant Phyllanthus niruri (Phyllanthaceae).Email this article to a colleague.
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We examined the geno-, cyto- and overall toxicity of P. niruri whole plant ethanolic extract. The extract was administered as a single dose of 30 or 300 mg/kg to laboratory rats by gavage, accompanied by negative (0.9% saline) and positive (10 mg/mL N-ethyl-N-nitrosourea) controls that were injected intramuscularly 48 h after extract administration. The ratio of polychromatic (PCE)/normochromatic erythrocytes (NCE) from femur bone marrow was scored for genotoxicity. Cytotoxicity was determined using descending concentrations (0.2-0.0125 g/mL) of the extract incubated with peripheral blood mononuclear cells. Lactate dehydro...
Source: Genetics and Molecular Research - February 3, 2012 Category: Genetics & Stem Cells Authors: Asare GA, Bugyei K, Sittie A, Yahaya ES, Gyan B, Adjei S, Addo P, Wiredu EK, Adjei DN, Nyarko AK Tags: Genet Mol Res Source Type: research
Two Studies Find that Patients Want Access to their Health Records, Including Clinical Pathology Test DataEmail this article to a colleague.
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Patients are ready to ready access to their medical records; but physicians are wary Data from two studies here in the United States affirms that patients want access to their health records. Consequently, health systems are increasingly making it easier for patients to get access to prescription lists, medical laboratory test results and now even [...] (Source: Dark Daily)
Source: Dark Daily - February 3, 2012 Category: Laboratory Medicine Authors: jude Tags: Laboratory News Laboratory Pathology Annals of Internal Medicine Beth Israel Deaconess Medical Center clinical laboratory Donna Zulman Geisinger Health System Harborview Medical Center harvard medical school kaiser permanente Kenneth S Source Type: news
Twitter is harder to resist than cigarettes and alcohol, study findsEmail this article to a colleague.
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People are more likely to give in to urge to tweet or check email than other cravings, say US researchersTweeting or checking emails may be harder to resist than cigarettes and alcohol, according to researchers who tried to measure how well people could resist their desires.They even claim that while sleep and sex may be stronger urges, people are more likely to give in to longings or cravings to use social and other media.A team headed by Wilhelm Hofmann of Chicago University's Booth Business School say their experiment, using BlackBerrys, to gauge the willpower of 205 people aged between 18 and 85 in and around the Germa...
Source: Guardian Unlimited Science - February 3, 2012 Category: Science Authors: James Meikle Tags: Psychology Twitter Internet Technology Media Blogging Newspapers & magazines Digital media Smoking Society Alcohol Email Computing Science United States World news The Guardian Source Type: news
Ascites due to lupus peritonitis: a rare form of onset of systemic lupus erythematosusEmail this article to a colleague.
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O lúpus eritematoso sistêmico (LES) frequentemente cursa com serosites. Cerca de 16% dos pacientes lúpicos apresentam acometimento de pleura e pericárdio. O acometimento peritoneal, no entanto, é especialmente raro, ocorrendo clinicamente em pequeno grupo de pacientes. O presente estudo trata do caso de uma paciente de 47 anos com diagnóstico de lúpus discoide que evoluiu com manifestações sistêmicas da doença, caracterizadas por distensão e dor abdominal significativas, astenia, emagrecimento, sinais propedêuticos de ascite e diarreia aguda baixa e não invasiva. Foi realizada exaustiva investigação diagnó...
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
25-Hydroxyivitamin D3 levels in patients with systemic lupus erythematosus and its association with clinical parameters and laboratory testsEmail this article to a colleague.
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CONCLUSIONS: High prevalence of 25(OH)D insufficiency/deficiency was found in patients with SLE (57.7%), with statistically significant difference as compared with the comparison group. No association of vitamin D insufficiency/deficiency was observed with the clinical variables and laboratory tests studied. The authors emphasize the importance of determining 25(OH)D serum levels in all patients with SLE, regardless of where they live and time to disease diagnosis (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - February 3, 2012 Category: Rheumatology Source Type: research
Prediction of environmental concentrations of glucocorticoids: The River Thames, UK, as an example.Email this article to a colleague.
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Abstract
Synthetic glucocorticoids (GCs) are consumed in large amounts as anti-inflammatory and immunosuppressive drugs worldwide. Based on what has been learnt from studies of other human pharmaceuticals, they are likely to be present in the aquatic environment. However, to date, information on the environmental concentrations of GCs is very limited. The situation is complicated by the fact that a considerable number of GCs are in everyday use in most developed countries. Hence, obtaining a full picture of GC concentrations in the aquatic environment using the traditional analytical chemistry approach would be tim...
Source: Environment International - February 3, 2012 Category: Environmental Health Authors: Kugathas S, Williams RJ, Sumpter JP Tags: Environ Int Source Type: research
Response to: Lack of intra-laboratory reproducibility in using Platelia Aspergillus enzyme immunoassay test for detection of Aspergillus galactomannan antigenEmail this article to a colleague.
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Bizzini A, Marchetti O, Meylan P (Source: The Aspergillus Website - articles)
Source: The Aspergillus Website - articles - February 3, 2012 Category: Respiratory Medicine Source Type: news
Quantitative assessment of visual behavior in disorders of consciousnessEmail this article to a colleague.
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In this study we aimed to provide a quantitative assessment of visual tracking behavior
in response to moving stimuli in DoC patients. Nine VS patients and nine MCS patients were recruited in a Neurorehabilitation
Unit for patients with chronic DoC; 11 matched healthy subjects were tested as the control group. All participants underwent
a quantitative evaluation of eye-tracking pattern by means of a computerized infrared eye-tracker system; stimuli were represented
by a red circle or a small color picture slowly moving on a PC monitor. The proportion of on- or off-target fixations differed
significantly between MCS an...
Source: Journal of Neurology - February 3, 2012 Category: Neurology Tags: Journal of Neurology Source Type: research
Improving test properties for neonatal cystic fibrosis screening in the Netherlands before the nationwide start by May 1st 2011Email this article to a colleague.
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Abstract When new technical possibilities arise in health care, often attunement is needed between different actors from the perspectives
of research, health care providers, patients, ethics and policy. For cystic fibrosis (CF) such a process of attunement in
the Netherlands started in a committee of the Health Council on neonatal screening in 2005. In the balancing of pros and cons
according to Wilson and Jungner criteria, the advantages for the CF patient were considered clear, even though CF remains
a severe health problem with treatment. Nevertheless, screening was not started then, mainly since the spec...
Source: Journal of Inherited Metabolic Disease - February 3, 2012 Category: Internal Medicine Tags: Journal of Inherited Metabolic Disease Source Type: research
Clonal antigen receptor gene PCR products outside the expected size rangeEmail this article to a colleague.
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Abstract Polymerase chain reaction (PCR) of the antigen receptor genes has clinical utility in establishing clonality in lymphoproliferations,
which is an important correlate of lymphoid neoplasia. The most frequently used procedures for this purpose were developed
by the BIOMED-2 consortium. One of the criteria for establishing monoclonality using PCR of the antigen receptor genes is
the finding of an abundant amplicon within a size range determined by the positions of the PCR primers and the known variability
in size inherent in the recombination events that assemble a functional antigen receptor gene. How...
Source: Journal of Hematopathology - February 3, 2012 Category: Pathology Tags: Journal of Hematopathology Source Type: research
Caris Diagnostics Announces Name Change to Miraca Life SciencesEmail this article to a colleague.
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TOKYO and IRVING, Texas, Feb. 3, 2012 (GLOBE NEWSWIRE) -- Caris Diagnostics, specializing in academic-caliber anatomic pathology services, today announced a company name change to Miraca Life Sciences following its November 2011 acquisition by Tokyo-based Miraca Holdings Inc., Japan's largest clinical diagnostics and laboratory testing service provider. The name change, which is effective February 20, 2012, follows a successful integration process and will be reflected in all marketing and communications. (Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - February 3, 2012 Category: Pharmaceuticals Source Type: news
New international standards to aid data sharingEmail this article to a colleague.
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Led by researchers at University of Oxford (UK) and the Harvard Stem Cell Institute (HSCI) at Harvard University, (USA), more than 50 collaborators at over 30 scientific organizations around the globe have agreed on a common standard for integrating biological data sets. This will make it possible to consistently describe the enormous and radically different databases that are compiled in the biosciences in fields ranging from genetics to stem cell science, to environmental studies.This collaborative effort provides a way for scientists in widely disparate life science fields to co-ordinate each other's findings by allowin...
Source: MEDEV News - February 3, 2012 Category: Universities & Medical Training Source Type: news
BioConference Live Announces 2012 Virtual Event ScheduleEmail this article to a colleague.
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Free Virtual Events at http://www.BioConferenceLive.com focusing on the Clinical Diagnostics, Life Sciences, and Laboratory Animal Sciences Community(PRWeb January 31, 2012)Read the full story at http://www.prweb.com/releases/2012/1/prweb9146126.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 3, 2012 Category: Pharmaceuticals Source Type: news
Reference values of thirty-one frequently used laboratory markers for 75-year-old males and females.Email this article to a colleague.
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Conclusion. There were minor differences between reference intervals calculated with and without individuals with cardiovascular diseases. Several of the reference intervals differed from Scandinavian reference intervals based on younger individuals (Nordic Reference Interval Project).
PMID: 22300333 [PubMed - as supplied by publisher] (Source: Upsala Journal of Medical Sciences)
Source: Upsala Journal of Medical Sciences - February 3, 2012 Category: Journals (General) Authors: Ryden I, Lind L, Larsson A Tags: Ups J Med Sci Source Type: research
Human Nonvisual Responses to Simultaneous Presentation of Blue and Red Monochromatic LightEmail this article to a colleague.
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Blue light sensitivity of melatonin suppression and subjective mood and alertness responses in humans is recognized as being melanopsin based. Observations that long-wavelength (red) light can potentiate responses to subsequent short-wavelength (blue) light have been attributed to the bistable nature of melanopsin whereby it forms stable associations with both 11-cis and all-trans isoforms of retinaldehyde and uses light to transition between these states. The current study examined the effect of concurrent administration of blue and red monochromatic light, as would occur in real-world white light, on acute melatonin supp...
Source: Journal of Biological Rhythms - February 3, 2012 Category: Research Authors: Papamichael, C., Skene, D. J., Revell, V. L. Tags: Articles Source Type: research
The Ability to Entrain to Long Photoperiods Differs between 3 Drosophila melanogaster Wild-Type Strains and Is Modified by Twilight SimulationEmail this article to a colleague.
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The ability to adapt to different environmental conditions including seasonal changes is a key feature of the circadian clock. Here, we compared the ability of 3 Drosophila melanogaster wild-type strains to adapt rhythmic activity to long photoperiods simulated in the laboratory. Fruit flies are predominantly crepuscular with activity bouts in the morning (M) and evening (E). The M peak follows dawn and the E peak follows dusk when the photoperiod is extended. We show that this ability is restricted to a certain extension of the phase angle between M and E peaks, such that the E peak does not delay beyond a certain phase u...
Source: Journal of Biological Rhythms - February 3, 2012 Category: Research Authors: Rieger, D., Peschel, N., Dusik, V., Glotz, S., Helfrich-Forster, C. Tags: Articles Source Type: research
Establishing a web-based integrated surveillance system for early detection of infectious disease epidemic in rural China: a field experimental studyEmail this article to a colleague.
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DiscussionAlthough syndromic surveillance system has mostly established in developed areas, there are opportunities and advantages of developing it in rural China. The project will contribute to knowledge, experience and evidence on the establishment of an integrated surveillance system, which aims to provide early warning of disease epidemics in developing countries. (Source: BMC Medical Informatics and Decision Making - Latest articles)
Source: BMC Medical Informatics and Decision Making - Latest articles - February 3, 2012 Category: Information Technology Authors: Wei-rong YanShao-fa NieBiao XuHeng-jin DongLars PalmVinod Diwan Source Type: research
A rare gastrointestinal presentation of a common malignancyEmail this article to a colleague.
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Clinical presentation A 61-year-old man presented with a 4-week history of rectal bleeding, constipation, bloating, abdominal distension and low back pain. His bowels had not opened for 4 days prior to admission. Physical examination revealed a distended, tympanic abdomen. Routine laboratory tests confirmed renal failure (urea 13 mmol/l, creatinine 200 μmol/l), hypercalcaemia (3.7 mmol/l), albumin 32 g/l and C-reactive protein (CRP) 25 mg/l. Parathormone was suppressed (7 pg/l (15–65)). Abdominal x-ray suggested an ileus. CT abdomen revealed mural thickening of the left hemi-colo...
Source: Gut - February 3, 2012 Category: Gastroenterology Authors: McCorry, R. B., Nair, B., Mooney, P., Shields, P. L. Tags: GUT Snapshot Editor ' s quiz: GI snapshot Source Type: research
Acute Genital Ulcers in Nonsexually Active Young Girls: Case Series, Review of the Literature, and Evaluation and Management RecommendationsEmail this article to a colleague.
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Abstract: Acute genital ulcers rarely occur in nonsexually active young girls. When present, they can cause significant physical and emotional distress for the patient and her parents, and prompt an evaluation for sexual abuse and sexually transmitted diseases. With this review, we aim to further characterize acute genital ulcers in nonsexually active young girls by reviewing the medical records of patients with this disorder and to offer an approach to the diagnosis, evaluation, and treatment of acute genital ulcers based on our understanding and knowledge of this condition. We retrospectively review our understanding ...
Source: Pediatric Dermatology - February 3, 2012 Category: Dermatology Authors: Ilana S. RosmanDavid R. BerkSusan J. BaylissAndrew J. WhiteDiane F. Merritt Tags: CLINICAL AND LABORATORY INVESTIGATION Source Type: research
Removing Hexazinone from Groundwater with Microbial Bioreactors.Email this article to a colleague.
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Abstract
Hexazinone, a triazine herbicide that is often detected as a ground and surface water contaminant, inhibits electron transport in photosynthetic organisms and is toxic to primary producers that serve as the base of the food chain. This laboratory study evaluated the ability of two types of microbial reactors, i.e., a vegetable oil-based nitrogen-limiting biobarrier and an aerobic slow sand filter, as methods for removing hexazinone from simulated groundwater. The N-limiting biobarriers degraded hexazinone, but did so with a 52 week incubation period and a removal efficiency that varied greatly among repli...
Source: Current Microbiology - February 3, 2012 Category: Microbiology Authors: Hunter WJ, Shaner DL Tags: Curr Microbiol Source Type: research
Collective actionEmail this article to a colleague.
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(European Molecular Biology Laboratory) Genetic switches called enhancers and the molecules that activate them can be used to draw a cell's family tree, EMBL scientists have found. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 3, 2012 Category: Biology Source Type: news
Serum osmolarity as an outcome predictor in hospital emergency medical admissions.Email this article to a colleague.
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CONCLUSION: Admission osmolarity, a simple calculation, is associated with the risk of mortality in acutely ill medical patients; deviations outside the normal range are relevant. A useful clinical predictive algorithm requires the incorporation of additional predictors.
PMID: 22284254 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - February 2, 2012 Category: Internal Medicine Authors: Nicholson T, Bennett K, Silke B Tags: Eur J Intern Med Source Type: research
How Red Wine's Resveratrol Confers Health BenefitsEmail this article to a colleague.
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Scientists have found out why resveratrol, a chemical naturally found in red wine, grapes, and some other fruit and vegetables, has health benefits, according to an article published in the journal Cell, February 3rd issue. The researchers, from the Laboratory of Obesity and Aging Research at the NIH's National Heart, Lung, and Blood Institute, explain that resveratrol inhibits PDEs (phosphodiesterases), proteins (enzymes) that play a crucial role in cell energy regulation. Resveratrol's molecular formula is C14H12O3... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 2, 2012 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news
For Military Researchers, the Butterfly is the Ultimate Drone [Video]Email this article to a colleague.
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Butterflies are not merely beautiful. They use a complex pattern of rapid wing flapping and body deformation to execute impressive aerial acrobatics. This ability has not escaped the U.S. military, which is turning to these insects for ideas on how to create ever-smaller drone aircraft to execute reconnaissance, search-and-rescue and environmental monitoring missions. [View a slide show featuring different drones used by the U.S. military.] The Air Force Research Laboratory at Wright-Patterson Air Force Base in Ohio is testing drones less than 60 centimeters long roughly the wingspan of an Atlantic Puffin with the hope the...
Source: Scientific American - Official RSS Feed - February 2, 2012 Category: Science Tags: Evolution,Technology,More Science Source Type: research
TDP-43 pathology in a case of hereditary spastic paraplegia with a NIPA1/SPG6 mutationEmail this article to a colleague.
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We present the first neuropathological description of a patient with
a NIPA1 mutation, and clinical phenotype of complicated HSP with motor neuron disease-like syndrome and cognitive decline. Postmortem
examination revealed degeneration of lateral corticospinal tracts and dorsal columns with motor neuron loss. TDP-43 immunostaining
showed widespread spinal cord and cerebral skein-like and round neuronal cytoplasmic inclusions. We ruled out NIPA1 mutations in 419 additional cases of motor neuron disease. These findings suggest that hereditary spastic paraplegia due
to NIPA1 mutations could represent a TDP-43 proteinopat...
Source: Acta Neuropathologica - February 2, 2012 Category: Neurology Tags: Acta Neuropathologica Source Type: research
Should we really fear 'new flesh-eating bacteria'?Email this article to a colleague.
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Conclusion
This interesting study helps explain why healthcare-acquired MRSA infections are rarely found in healthy individuals. It found that expression of a gene that produces one of the proteins responsible for MRSA’s antibiotic resistance caused it to be less toxic. It also showed that typical community-acquired MRSA strains express less of this antibiotic-resistance protein, but are more toxic.
However, this intriguing lab study did not investigate the transmission, effects or number of cases of community-acquired MRSA in the UK, discussion of which formed the majority of the news reports. On this basis, the researc...
Source: NHS News Feed - February 2, 2012 Category: Consumer Health News Tags: Medical practice Source Type: news
An explorative analysis of secretory receptor for advanced glycation endproducts in primary focal segmental glomerulosclerosisEmail this article to a colleague.
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Conclusion This study showed that only the serum level of esRAGE, not sRAGE, was higher in the FSGS group than in the IgAN and control
groups. The amount of 24-h proteinuria was also related to the serum level of esRAGE in the FSGS group.
Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10157-012-0599-1Authors
Harin Rhee, Division of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, 179 Gudeok-ro, Seo-gu, Busan, 602-739 Republic of KoreaSang Heon Song, Division of Nephrology, Department of Internal Medicine, Pusan National University ...
Source: Clinical and Experimental Nephrology - February 2, 2012 Category: Urology & Nephrology Tags: Clinical and Experimental Nephrology Source Type: research
Phase II clinical study of DD-723 (perflubutane): dose–response study in patients with breast tumorsEmail this article to a colleague.
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Conclusions An intermediate dose showed the highest efficacy in terms of overall contrast effect. Contrast-enhanced ultrasonography is
safe and useful when used in differential diagnosis.
Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s10396-011-0342-7Authors
Yukio Miyamoto, Department of Diagnostic Imaging, Jikei University Hospital, 3-19-18 Nishishinbashi, Minato, Tokyo, 105-8471 JapanToshikazu Ito, Department of Surgery, Rinku General Medical Center, Osaka, JapanEtsuo Takada, Center of Medical Ultrasonics, Dokkyo Medical University, Tochigi, JapanKiyoka Omoto, Department...
Source: Journal of Medical Ultrasonics - February 2, 2012 Category: Radiology Tags: Journal of Medical Ultrasonics Source Type: research
Characterization of Epstein-Barr virus type 1 nuclear antigen 3C sequence patterns of nasopharyngeal and gastric carcinomas in northern ChinaEmail this article to a colleague.
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In this study, we successfully amplified 26 Epstein-Barr virus (EBV)-associated
gastric carcinomas (EBVaGCs), 50 nasopharyngeal carcinomas (NPCs) and 27 throat washing (TW) samples from healthy donors.
Based on a phylogenetic tree, the samples could be divided into three patterns. 3C-6 was the predominant subtype in northern
China, and the variations between the strains sequenced in our study and those from southern China and Japan were similar,
but differences were also identified. The distribution of EBNA3C subtypes among EBVaGCs, NPCs and healthy donors was not significantly
different. These data suggest that EBNA3...
Source: Archives of Virology - February 2, 2012 Category: Virology Tags: Archives of Virology Source Type: research
UCLA researchers identify peptide that inhibits replication of hepatitis C virusEmail this article to a colleague.
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Researchers from UCLA's Jonsson Comprehensive Cancer Center have identified a cell-permeable peptide that inhibits a hepatitis C virus protein and blocks the viral replication that can lead to liver cancer and cirrhosis.
The finding by Dr. Samuel French, a UCLA assistant professor of pathology and senior author of the research, builds on previous work by French's laboratory that identified two cellular proteins that are important factors in hepatitis C virus infection.
In that earlier research, French and his team set out to identify the cellular factors involved in hepatitis C replication. Using mass spectro...
Source: UCLA Newsroom: Health Sciences - February 2, 2012 Category: Universities & Medical Training Source Type: news
