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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

H. pylori infection high in metabolic syndrome patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Helicobacter pylori infection is significantly associated with presence of the metabolic syndrome, show results from a large Japanese population study published in the American Journal of Gastroenterology. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - December 19, 2008 Category: Lipidology Source Type: news

[Research Articles] Structural characterization of Bordetella parapertussis lipid AEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bordetella parapertussis like B. pertussis, is a causal agent of whooping cough but is not a strictly human pathogen. Because its endotoxin, a major structural component of the Gram-negative outer membrane, is an important virulence factor, we have analyzed the structure of its toxic lipid domain, in one rough and two smooth bacterial strains. Chemical analyses and mass spectra obtained before and after recently developed mild-alkali treatments revealed that the lipids A have the common bisphosphorylated β-(1->6)-linked D-glucosamine disaccharide with hydroxytetradecanoic acid in amide linkages. All three strains h...
Source: The Journal of Lipid Research - April 7, 2009 Category: Lipidology Authors: El Hamidi, A., Novikov, A., Karibian, D., Perry, M. B., Caroff, M. Tags: Research Articles Source Type: journals

Brucella infection linked with atherogenic lipid profileEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Acute infection with Brucella melitensis is associated with an atherogenic lipid profile that remains several months after treatment for the bacterium, a Greek study suggests. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - June 25, 2009 Category: Lipidology Source Type: news

Structural characterization of Bordetella parapertussis lipid A [Research Articles]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bordetella parapertussis like B. pertussis, is a causal agent of whooping cough but is not a strictly human pathogen. Because its endotoxin, a major structural component of the Gram-negative outer membrane, is an important virulence factor, we have analyzed the structure of its toxic lipid domain, in one rough and two smooth bacterial strains. Chemical analyses and mass spectra obtained before and after recently developed mild-alkali treatments revealed that the lipids A have the common bisphosphorylated β-(1->6)-linked D-glucosamine disaccharide with hydroxytetradecanoic acid in amide linkages. All three strains h...
Source: The Journal of Lipid Research - April 6, 2009 Category: Lipidology Authors: El Hamidi, A., Novikov, A., Karibian, D., Perry, M. B., Caroff, M. Tags: Research Articles Source Type: journals

Prostate specific antigen levels reduced by statin therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Study results show that statin use reduces prostate-specific antigen levels in patients with prostate cancer. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 20, 2009 Category: Lipidology Source Type: news

Association of serum levels of lipid and its novel constituents with the different stages of esophageal carcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The present study shows that the decreased oxLDL and oxLDL-ab and the elevated oxLDL-lgM serum levels may relate to the development and progression of ESSC. (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - October 29, 2009 Category: Lipidology Authors: Yutao DiaoHao LiHuiqing LiYingzhi ZhouQing MaYan WangDong Li Source Type: journals

Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies [Research Articles]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes the successful production and characterization of a murine monoclonal antibody, LT1002, directed against S1P, using novel immunization and screening methods applied to bioactive lipids. We also report the successful generation of LT1009, the humanized variant of LT1002, for potential clinical use. Both LT1002 and LT1009 have high affinity and specificity for S1P and do not cross-react with structurally related lipids. Using an in vitro bioassay, LT1002 and LT1009 were effective in blocking S1P-mediated release of the pro-angiogenic and prometastatic cytokine, interleukin-8, from human ovarian carcinom...
Source: The Journal of Lipid Research - October 15, 2009 Category: Lipidology Authors: O'Brien, N., Jones, S. T., Williams, D. G., Cunningham, H. B., Moreno, K., Visentin, B., Gentile, A., Vekich, J., Shestowsky, W., Hiraiwa, M., Matteo, R., Cavalli, A., Grotjahn, D., Grant, M., Hansen, G., Campbell, M.-A., Sabbadini, R. Tags: Research Articles Source Type: journals

Diet induced changes in omega 3 and 6 fatty acids may reduce prostate cancer cell growthEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Consumption of a low fat diet leading to reduced omega-6 and increased omega-3 fatty acids is associated with decreased prostate cancer cell growth, according to the results of a US trial. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 19, 2009 Category: Lipidology Source Type: news

Low triglycerides are risk factor for hemorrhagic strokeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Low triglyceride levels are associated with an increased risk for hemorrhagic stroke, particularly in men and those with hypertension or low lipid levels, a large French population-based study has found. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 18, 2009 Category: Lipidology Source Type: news

Statins and LXR receptor agonists offer ovarian cancer hopeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Statins and liver X receptor agonists could become an effective adjunct therapy against ovarian cancer, US researchers say. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 12, 2009 Category: Lipidology Source Type: news

Concern about possible adverse lipid effects of high selenium levelsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Individuals with increased levels of plasma selenium have elevated total and non-high-density lipoprotein cholesterol levels, show results published in the Journal of Nutrition. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 17, 2009 Category: Lipidology Source Type: news

PON-1 dysregulation in obesity linked to reduced cellular repair, protectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Reduced paraoxonase -1 activity may be one mechanism underlying the accelerated cellular oxidative damage and arteriosclerosis seen in obese individuals, say Italian researchers. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - October 21, 2009 Category: Lipidology Source Type: news

Baseline lipids not predictive for stroke in NOMASEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Results from the Northern Manhattan Study show that baseline lipid levels were not associated with incident stroke in a cohort of older individuals without previous myocardial infarction. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 13, 2009 Category: Lipidology Source Type: news

Men with low cholesterol have reduced risk for high-grade prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Study results show that men with low total cholesterol have a reduced risk for high-grade prostate cancer. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 10, 2009 Category: Lipidology Source Type: news

A diet including high n-3 fatty acids lowers triglycerides in patients with HIVEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A controlled diet including a high concentration of n-3 fatty acids significantly reduces triglyceride concentrations in patients with HIV, report researchers. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - October 28, 2009 Category: Lipidology Source Type: news

Chronic kidney disease delays VLDL-apoB-100 particle catabolism: potential role of apolipoprotein C-III [Patient-Oriented and Epidemiological Research]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To determine the relative contribution of obesity and/or insulin resistance (IR) in the development of dyslipidemia in chronic kidney disease (CKD), we investigated the transport of apolipoprotein (apo) B-100 in nonobese, nondiabetic, nonnephrotic CKD subjects and healthy controls (HC). We determined total VLDL, VLDL1, VLDL2, intermediate density lipoprotein (IDL), and LDL-apoB-100 using intravenous D3-leucine, GC-MS, and multicompartmental modeling. Plasma apoC-III and apoB-48 were immunoassayed. In this case control study, we report higher plasma triglyceride, IDL-, VLDL-, VLDL1-, and VLDL2-apoB-100 concentrations in CKD...
Source: The Journal of Lipid Research - November 13, 2009 Category: Lipidology Authors: Chan, D. T., Dogra, G. K., Irish, A. B., Ooi, E. M., Barrett, P. H., Chan, D. C., Watts, G. F. Tags: Patient-Oriented and Epidemiological Research Source Type: journals

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response [Research Articles]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recent studies have shown a link between obesity and endoplasmic reticulum (ER) stress. Perturbations in ER homeostasis cause ER stress and activation of the unfolded protein response (UPR). Adipocyte differentiation contributes to weight gain, and we have shown that markers of ER stress/UPR activation, including GRP78, phospho-eIF2, and spliced XBP1, are upregulated during adipogenesis. Given these findings, the objective of this study was to determine whether attenuation of UPR activation by the chemical chaperone 4-phenylbutyrate (4-PBA) inhibits adipogenesis. Exposure of 3T3-L1 preadipocytes to 4-PBA in the presence of...
Source: The Journal of Lipid Research - November 13, 2009 Category: Lipidology Authors: Basseri, S., Lhotak, S., Sharma, A. M., Austin, R. C. Tags: Research Articles Source Type: journals

BMI and adiponectin affect APOE impact on lipid profile of obese childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The impact of apolipoprotein E gene variants on lipid profile in obese children and adolescents is affected by body mass index and adiponectin levels, research suggests. (Source: MedWire News - Lipidology)
Source: MedWire News - Lipidology - November 13, 2009 Category: Lipidology Source Type: news

Metabolic abnormalities in chronic kidney disease that contribute to cardiovascular disease, and nutritional initiatives that may diminish the risk.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 3DOI: 10.1097/MOL.0b013e32831ef234Authors: Chmielewski, Michal a,b; Carrero, Juan Jesus a; Stenvinkel, Peter a; Lindholm, Bengt a (Source: Current Opinion in Lipidology)
Source: Current Opinion in Lipidology - December 24, 2008 Category: Lipidology Tags: Abstract HTML PDF (143 K) Source Type: journals

Lipid-Altering Efficacy of Ezetimibe/Simvastatin 10/20mg Compared with Rosuvastatin 10mg in High-Risk Patients with and Without Type 2 Diabetes Mellitus (T2DM)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Synopsis: Many patients fail to achieve recommended LDL-C goals with statin monotherapy and are at increased risk of coronary events. Hypercholesterolemic patients at high cardiovascular risk who failed to achieve adequate LDL-C lowering with prior statin monotherapy were switched to ezetimibe/simvastatin 10/20mg (EZE/SIMVA) or rosuvastatin 10mg (ROSUVA). (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - April 30, 2009 Category: Lipidology Authors: Philippe Brudi, Helena Vaverkova, Michel Farnier, Maurizio Averna, Margus Viigimaa, Qian Dong, Arvind Shah, Amy O. Johnson-Levonas, Luc Missault Tags: Abstracts Source Type: journals