Microbiology 
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63693 records returned
Chemical Double Act Triggers Spreading Of Spores
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Microbiology: Together, two molecules help fungi figure out when to release spores (Source: Chemical and Engineering News)
Source: Chemical and Engineering News - February 3, 2012 Category: Chemistry Authors: Katharine Sanderson Source Type: research
Deciphering the role of Paenibacillus strain Q8 in the organic matter recycling in the acid mine drainage of CarnoulesEmail this article to a colleague.
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Conclusions:
AMDs have been studied for years especially with regard to interactions between bacteria and the inorganic compartment hosting them. To date, no study reported the role of microorganisms in the recycling of the organic matter. The present work suggests that the strain Q8 might play an important role in the community by recycling the scarce organic matter (cellulose, hemicellulose, starch...), especially when the conditions change. Furthermore, function-based screening of a Q8 DNA library allowed to assign an amylolytic function to a gene previously unknown. AMDs could be considered as a reservoir of genes with...
Source: Microbial Cell Factories - February 3, 2012 Category: Microbiology Authors: Francois DelavatVincent PhalipAnne ForsterMarie-Claire LettDidier Lievremont Source Type: research
Transcriptome profiling of a curdlan-producing Agrobacterium reveals conserved regulatory mechanisms of exopolysaccharide biosynthesisEmail this article to a colleague.
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Conclusions:
This study identifies several mechanisms regulating the synthesis of curdlan, an EPS with numerous applications. These mechanisms are potential metabolic engineering targets for improving the industrial production of curdlan from Agrobacterium sp. ATCC 31749. Furthermore, many of the genes identified in this study are highly conserved across microbial genomes, and we propose that the molecular elements identified in this study may serve as universal regulators of microbial EPS synthesis. (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - February 3, 2012 Category: Microbiology Authors: Anne RuffingRachel Ruizhen Chen Source Type: research
Starmerella bombicola influences the metabolism of Saccharomyces cerevisiae at pyruvate decarboxylase and alcohol dehydrogenase level during mixed wine fermentationEmail this article to a colleague.
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Conclusion:
In mixed fermentation, S. bombicola immobilized cells greatly affected the fermentation behavior of S. cerevisiae and the analytical composition of wine. The influence of S. bombicola on S. cerevisiae was not limited to a simple additive contribution. Indeed, its presence caused metabolic modifications during S. cerevisiae fermentation causing variation in the gene expression and enzymatic activity of alcohol deydrogenase and pyruvate decarboxilase. (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - February 3, 2012 Category: Microbiology Authors: Vesna MilanovicMaurizio CianiLucia OroFrancesca Comitini Source Type: research
Seroprevalence of Hepatitis E Virus infection in rural and urban populations, TunisiaEmail this article to a colleague.
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This study investigated the prevalence and risk factors of HEV infection in Tunisian adult general population, either in blood donors (n=687) or in patients hospitalised for acute hepatitis (n=202). The mode of transmission differed between these two populations: contact with animals and living in rural habitat were the main risk factors of being in contact with HEV in asymptomatic blood donors, while HEV was contracted through contaminated water in symptomatic cases. HEV seroprevalence in adult blood donors in Tunisia was relatively low (5.4%) and increased with age.© 2012 The Authors Clinical Microbiology and Infection ...
Source: Clinical Microbiology and Infection - February 3, 2012 Category: Microbiology Authors: Neffati HoucineRitter JacquesFeki SalmaDron Anne‐GaëlleSlim AminHassine MohsenBraham HamadiRamiere ChristopheAndre PatriceAouni MahjoubScholtes Caroline Source Type: research
Carbapenemase‐producing Enterobacteriaceae: A call for action!Email this article to a colleague.
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(Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - February 3, 2012 Category: Microbiology Authors: Patrice Nordmann Giuseppe Cornaglia Source Type: research
Ultrahigh-resolution full-field optical coherence tomography using spatial coherence gating and quasi-monochromatic illuminationEmail this article to a colleague.
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We developed an ultrahigh-resolution full-field optical coherence tomography (FF-OCT) microscope that is based on the spatial, rather than the temporal, coherence gating. The microscope is capable of observing three-dimensional microbiological structures as small as ... (Source: Optics Letters)
Source: Optics Letters - February 3, 2012 Category: Physics Authors: Avner Safrani Ibrahim Abdulhalim Source Type: research
Detection of Extended-Spectrum β-Lactamase in Enterobacter spp.– Evaluation of Six Phenotypic TestsEmail this article to a colleague.
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Microbial Drug Resistance Feb 2012, Vol. 18, No. 1: 66-70. (Source: Microbial Drug Resistance)
Source: Microbial Drug Resistance - February 2, 2012 Category: Microbiology Tags: article Source Type: research
Manuka Honey Could Be The Answer For Treating And Preventing Wound InfectionsEmail this article to a colleague.
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Manuka honey could help clear chronic wound infections and even prevent them from developing in the first place, according to a new study published in Microbiology. The findings provide further evidence for the clinical use of manuka honey to treat bacterial infections in the face of growing antibiotic resistance. Streptococcus pyogenes is a normal skin bacterium that is frequently associated with chronic (non-healing) wounds. Bacteria that infect wounds can clump together forming 'biofilms', which form a barrier to drugs and promotes chronic infection... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 2, 2012 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Carriage of encapsulated bacteria in Gabonese children with sickle cell anemiaEmail this article to a colleague.
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In conclusion, carriage and resistance rates are similar in children with and without SCA. Our data provide the basis to guide empiric therapy of invasive diseases caused by S. pneumoniae, S. aureus and H. influenza in children in Gabon. (Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - February 2, 2012 Category: Microbiology Authors: F. SchaumburgB. BiallasE. Ngoune FeugapA. S. AlabiB. MordmüllerP. G. KremsnerM. P. GrobuschB. LellM. van der LindenG. PetersA. A. Adegnika Source Type: research
Hsp33 confers bleach resistance by protecting elongation factor Tu against oxidative degradation in Vibrio choleraeEmail this article to a colleague.
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SummaryThe redox‐regulated chaperone Hsp33 protects bacteria specifically against stress conditions that cause oxidative protein unfolding, such as treatment with bleach or exposure to peroxide at elevated temperatures. To gain insight into the mechanism by which expression of Hsp33 confers resistance to oxidative protein unfolding conditions, we made use of V. cholerae strain O395 lacking the Hsp33 gene hslO. We found that this strain, which is exquisitely bleach‐sensitive, displays a temperature‐sensitive (ts) phenotype during aerobic growth, implying that V. cholerae suffers from oxidative heat stress when cultiva...
Source: Molecular Microbiology - February 2, 2012 Category: Microbiology Authors: Wei‐Yun WholeyUrsula Jakob Source Type: research
Aerial development in Streptomyces coelicolor requires sortase activityEmail this article to a colleague.
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SUMMARYStreptomyces coelicolor is a multicellular bacterium whose life cycle encompasses three differentiated states: vegetative hyphae, aerial hyphae and spores. Amongst the factors required for aerial development are the ‘chaplins’, a family of eight secreted proteins that coat the surface of aerial hyphae. Three chaplins (the ‘long’ chaplins, ChpA, B and C) possess an LAXTG‐containing C‐terminal sorting signal and are predicted sortase substrates. The five remaining ‘short’ chaplins are presumed to be associated with the cell surface through interactions with the long chaplins. We show here that two sort...
Source: Molecular Microbiology - February 2, 2012 Category: Microbiology Authors: Andrew DuongDavid S. CapstickChristina Di BerardoKim C. FindlayAndrew HeskethHee‐Jeon HongMarie A. Elliot Source Type: research
A Turning Point for Natural Products Discovery – ESF‐EMBO Research Conference: Synthetic Biology of Antibiotic ProductionEmail this article to a colleague.
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Discussion identified future trends in the field.© 2012 Blackwell Publishing Ltd (Source: Molecular Microbiology)
Source: Molecular Microbiology - February 2, 2012 Category: Microbiology Authors: Eriko TakanoRoel BovenbergRainer Breitling Source Type: research
Expression of the RNA Recognition Motif protein RBP10 promotes a bloodstream‐form transcript pattern in Trypanosoma bruceiEmail this article to a colleague.
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AbstractWhen Trypanosoma brucei differentiates from the bloodstream form to the procyclic form, there are decreases in the levels of many mRNAs encoding proteins required for the glycolytic pathway, and the mRNA encoding the RNA Recognition Motif protein RBP10 decreases in parallel. We show that RBP10 is a cytoplasmic protein that is specific to bloodstream‐form trypanosomes, where it is essential. Depletion of RBP10 caused decreases in many bloodstream‐form‐specific mRNAs, with increases in mRNAs associated with the early stages of differentiation. The changes were similar to, but more extensive than, those caused b...
Source: Molecular Microbiology - February 2, 2012 Category: Microbiology Authors: Martin WurstBeate SeligerBaskhar Anand JhaCornelia KleinRafael QueirozChristine Clayton Source Type: research
A network of enzymes involved in repair of oxidative DNA damage in Neisseria meningitidisEmail this article to a colleague.
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ABSTRACTAlthough oxidative stress is a key aspect of innate immunity, little is known about how host‐restricted pathogens successfully repair DNA damage. Base excision repair (BER) is responsible for correcting nucleobases damaged by oxidative stress, and is essential for bloodstream infection caused by the human pathogen, Neisseria meningitidis. We have characterised meningococcal BER enzymes involved in the recognition and removal of damaged nucleobases, and incision of the DNA backbone. We demonstrate that the bi‐functional glycosylase/lyases Nth and MutM share several overlapping activities and functional redundanc...
Source: Molecular Microbiology - February 2, 2012 Category: Microbiology Authors: Krzysztofa NagorskaJan SilhanYanwen LiVladimir PelicicPaul S. FreemontGeoff S. BaldwinChristoph M. Tang Source Type: research
Ligand and antagonist driven regulation of the Vibrio cholerae quorum‐sensing receptor CqsSEmail this article to a colleague.
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SummaryQuorum sensing, a bacterial cell‐cell communication process, controls biofilm formation and virulence factor production in Vibrio cholerae, a human pathogen that causes the disease cholera. The major V. cholerae autoinducer is (S)‐3‐hydroxytridecan‐4‐one (CAI‐1). A membrane bound two‐component sensor histidine kinase called CqsS detects CAI‐1, and the CqsS‐ > LuxU‐ > LuxO phosphorelay cascade transduces the information encoded in CAI‐1 into the cell. Because the CAI‐1 ligand is known and because the signaling circuit is simple, consisting of only three proteins, this system is ideal for...
Source: Molecular Microbiology - February 2, 2012 Category: Microbiology Authors: Yunzhou WeiWai‐Leung NgJianping CongBonnie L. Bassler Source Type: research
RcsB‐BglJ activates the Escherichia coli leuO gene, encoding an H‐NS antagonist and pleiotropic regulator of virulence determinantsEmail this article to a colleague.
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SummaryThe LysR‐type transcription factor LeuO is involved in regulation of pathogenicity determinants and stress responses in Enterobacteriaceae, and acts as antagonist of the global repressor H‐NS. Expression of the leuO gene is repressed by H‐NS, and it is upregulated in stationary phase and under amino acid starvation conditions. Here, we show that the heterodimer of the FixJ/NarL‐type transcription regulators RcsB and BglJ strongly activates expression of leuO and that RcsB‐BglJ regulates additional loci. Activation of leuO by RcsB‐BglJ is independent of the Rcs phosphorelay system. RcsB‐BglJ binds to th...
Source: Molecular Microbiology - February 2, 2012 Category: Microbiology Authors: Thomas StratmannÜmit PulReinhild WurmRolf WagnerKarin Schnetz Source Type: research
Discrimination, Crypticity, and Incipient Taxa in EntamoebaEmail this article to a colleague.
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This study demonstrates that IP‐1 and VK‐1:NS trophozoites aggregate only with alike members and discriminate members of different strains based on behavioral and chemical signals. Combined morphological, behavioral/chemical, and ecological studies could improve Archamoebae phylogenies and define cryptic varieties. Evolutionary processes in which selection acted continuously and cumulatively on ancestors of Entamoeba populations gave rise to chemical and behavioral signals that allowed individuals to discriminate nonpopulation members and, gradually, to the emergence of new lineages; alternative views that claim a “D...
Source: The Journal of Eukaryotic Microbiology - February 2, 2012 Category: Microbiology Authors: Avelina EspinosaGuillermo Paz‐Y‐Miño‐C. Tags: Symposium Article Source Type: research
Superantigen profiles of emm and emm-like typeable and nontypeable pharyngeal streptococcal isolates of South IndiaEmail this article to a colleague.
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Conclusions:
Multiplex PCR analysis revealed the presence of superantigens in all the typeable strains irrespective of their emm types. However, the presence of superantigen genes in emm and emmL nontypeable strains has not been previously reported. In this study, presence of at least one or a combination of superantigen coding genes was identified in all the emm and emmL nontypeable strains. Thus, the superantigens may inevitably play an important role in the pathogenesis of these nontypeable strains in the absence of the primary virulence factor, M protein. (Source: Annals of Clinical Microbiology and Antimicrobials)
Source: Annals of Clinical Microbiology and Antimicrobials - February 2, 2012 Category: Microbiology Authors: Thangarajan Durai AnandThangamani RajeshJeyaprakash RajendhranParamasamy Gunasekaran Source Type: research
Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer.Email this article to a colleague.
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Abstract
A healthy human body contains at least tenfold more bacterial cells than human cells and the most abundant and diverse microbial community resides in the intestinal tract. Intestinal health is not only maintained by the human intestine itself and by dietary factors, but is also largely supported by this resident microbial community. Conversely, however, a large body of evidence supports a relationship between bacteria, bacterial activities and human colorectal cancer. Symbiosis in this multifaceted organ is thus crucial to maintain a healthy balance within the host-diet-microbiota triangle and accordingly,...
Source: Biological Reviews of the Cambridge Philosophical Society - February 2, 2012 Category: Biology Authors: Boleij A, Tjalsma H Tags: Biol Rev Camb Philos Soc Source Type: research
Morbidity of foreign travelers in Attica, Greece: a retrospective studyEmail this article to a colleague.
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Abstract Over the last decade, travel medicine was mainly focused on the epidemiology of diseases among travelers to developing countries.
However, less is known about travel-related morbidity in Europe. We evaluated the demographic and clinical characteristics
of foreign travelers to Greece during a 5-year period (01/01/2005 - 31/12/2009) who sought medical services from a network
of physicians performing house-call visits (SOS Doctors) in the area of Attica, Greece. Overall, 3,414 foreign travelers [children
(≤18 years of age): 27%] were identified; 151 (4.4%) required transfer to a hospital. The mo...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 1, 2012 Category: Microbiology Tags: European Journal of Clinical Microbiology & Infectious Diseases Source Type: research
Time to positivity of blood culture association with clinical presentation, prognosis and ESBL-production in Escherichia coli bacteremiaEmail this article to a colleague.
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Abstract The time to positivity (TTP) of blood cultures has been associated with increased mortality in bacteremia caused by several
microorganisms. The aim of this study is to evaluate the relationship between TTP and prognosis, clinical presentation and
extended spectrum B-lactamase (ESBL)-production in patients with Escherichia coli bacteremia. This is a retrospective observational study involving 226 adult patients with E. coli bacteremia. Data collected included underlying diseases, clinical presentation, prognosis factors, TTP, ESBL-production and
outcome. Thirty-one (14%) patients had severe sepsis and...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 1, 2012 Category: Microbiology Tags: European Journal of Clinical Microbiology & Infectious Diseases Source Type: research
Antibiotic susceptibility profiles and first report of TEM extended-spectrum β-lactamase in Pseudomonas fluorescens from coastal waters of the Kaštela Bay, CroatiaEmail this article to a colleague.
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Abstract The aim of this study was to investigate the antibiotic susceptibility profiles and the presence of extended-spectrum-β-lactamases
(ESBLs) in Pseudomonas fluorescens isolates from coastal waters of the Kaštela Bay, Croatia. Twenty-two water samples were collected during 2009. Isolates were
tested for susceptibilities to 13 antibiotics by Etest. ESBL production was confirmed by double-disk synergy test carried
out on Mueller–Hinton agar plates containing efflux pump inhibitor Phe-Arg-β-naphthylamide dihydrochloride. PCR and DNA sequencing
analysis were used to identify ESBL-encoding genes. The t...
Source: World Journal of Microbiology and Biotechnology - February 1, 2012 Category: Microbiology Tags: World Journal of Microbiology and Biotechnology Source Type: research
Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell linesEmail this article to a colleague.
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This study suggests different antiviral
functions of polyvalent IVIG and confirms their potential to inhibit a CMV infection in vitro, with profound differences between
the hereby used IVIG products.
Content Type Journal ArticleCategory Original PaperPages 1-10DOI 10.1007/s00430-012-0229-2Authors
K. Frenzel, Institute of Medical Virology, Helmut-Ruska-Haus, Charité University Medicine, Charitéplatz 1, 10117 Berlin, GermanyS. Ganepola, Department of Haematology, Oncology and Transfusion Medicine, Charité University Medicine, Berlin, GermanyD. Michel, Institute of Virology, University Hospital Ulm, Ulm, GermanyE....
Source: Medical Microbiology and Immunology - February 1, 2012 Category: Microbiology Tags: Medical Microbiology and Immunology Source Type: research
Biosecurity Runs Up Against Scientific Endeavor: NSABB And H5N1 RedactionsEmail this article to a colleague.
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In response to recent actions of the U.S. National Science Advisory Board for Biosecurity (NSABB), which recommended that two scientific journals withhold crucial details in upcoming reports about experiments with a novel strain of the bird flu virus, H5N1, the American Society for Microbiology (ASM) will publish a special series of commentaries by prominent scientists, including the acting chair of the NSABB, weighing in on whether the recommendations were necessary and what role biosecurity considerations should play in the dissemination of research findings... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 1, 2012 Category: Consumer Health News Tags: Bird Flu / Avian Flu Source Type: news
Lungs Infected With Plague Bacteria Also Become Playgrounds For Other MicrobesEmail this article to a colleague.
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Among medical mysteries baffling many infectious disease experts is exactly how the deadly pneumonic plague bacterium, Yersinia pestis, goes undetected in the first few day of lung infection, often until it's too late for medical treatment. New research from the University of North Carolina at Chapel Hill School of Medicine has opened a door to the answer. Researchers led by William E. Goldman, PhD, professor and chair of microbiology and immunology at the University of North Carolina at Chapel Hilland a leading authority on Y... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 1, 2012 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news
Halophilanema prolata n. gen., n. sp. (Nematoda: Allantonematidae), a parasite of the intertidal bug, Saldula laticollis (Reuter)(Hemiptera: Saldidae) on the Oregon coastEmail this article to a colleague.
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Halophilanema prolata (Nematoda: Allantonematidae) is described from the intertidal bug, Saldula laticollis on the Oregon coast. Infection rates ranged from 0 % to 85% depending on the microhabitat in the intertidal zone. Image: Parasitic female and juvenile stages of Halophilanema prolata removed from the hemocoel of the intertidal bug, Saldula laticollis on the Oregon coast. (Source: Parasites and Vectors)
Source: Parasites and Vectors - February 1, 2012 Category: Microbiology Authors: George Poinar Source Type: research
The major secreted protein Msp1/p75 is O-glycosylated in Lactobacillus rhamnosus GGEmail this article to a colleague.
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Conclusions:
In this study we have provided the first evidence of protein O-glycosylation in the probiotic L rhamnosus GG. The major secreted protein Msp1 is glycosylated with a ConA reactive glycan at the serine residues at 106 and 107. Glycosylation is not required for the peptidoglycan hydrolase activity of Msp1 nor for Akt activation capacity in epithelial cells, but appears to be important for its stability and protection against proteases. (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - February 1, 2012 Category: Microbiology Authors: Sarah LebeerIngmar ClaesCrina BalogGeert SchoofsTine VerhoevenKris NysIngemar von OssowskiWillem de VosHanne TytgatPatrizia AgostinisAiri PalvaEls Van DammeAndre DeelderSigrid De KeersmaeckerManfred WuhrerJos Vanderleyden Source Type: research
Chemotaxis of Burkholderia sp. strain SJ98 towards chloronitroaromatic compounds that it can metaboliseEmail this article to a colleague.
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Conclusions:
Burkholderia sp. strain SJ98 exhibits metabolic transformation of, and inducible chemotaxis towards CNACs. Its chemotactic responses towards these compounds are related to its previously demonstrated chemotaxis towards NACs that it can metabolise, but it is independently inducible from its chemotaxis towards succinate or aspartate. (Source: BMC Microbiology - Latest articles)
Source: BMC Microbiology - Latest articles - February 1, 2012 Category: Microbiology Authors: Janmejay PandeyNarinder SharmaFazlurrahman KhanAnuradha GhoshJohn OakeshottRakesh JainGunjan Pandey Source Type: research
Prolonged and Mixed non‐O157 E. coli Infection in an Australian HouseholdEmail this article to a colleague.
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This study illustrates the potentially complicated nature of non‐O157 STEC infections and the importance of molecular epidemiology in understanding disease clusters. (Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - February 1, 2012 Category: Microbiology Authors: Megan StaplesRikki MA GrahamChristine J DoyleHelen V SmithAmy V Jennison Source Type: research
Scabies and pediculosis: neglected diseases to highlightEmail this article to a colleague.
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(Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - February 1, 2012 Category: Microbiology Authors: O. Chosidow Source Type: research
NDM‐1, OXA‐48, and OXA‐181 carbapenemase‐producing Enterobacteriaceae in Sultanate of OmanEmail this article to a colleague.
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AbstractTwenty‐two carbapenem‐resistant enterobacterial isolates were recovered from patients hospitalized between October 2010 and March 2011 at the Royal Hospital of Muscat, Sultanate of Oman. Eleven NDM‐1, five OXA‐48 and one NDM‐1 plus OXA‐181 producers of diverse ST types were recovered from clinical samples. All carbapenemase genes were located on self‐conjugative plasmids and were nearly always associated to other resistance determinants, including extend‐spectrum ß‐lactamases and the ArmA methylase encoding resistance to aminoglycosides. This work highlights the dissemination of NDM‐1 and OXA...
Source: Clinical Microbiology and Infection - February 1, 2012 Category: Microbiology Authors: Laurent DortetLaurent PoirelFatma Al YaqoubiPatrice Nordmann Source Type: research
Statistical optimization of simple culture conditions to produce biomass of an ochratoxigenic‐ mold biocontrol yeast strainEmail this article to a colleague.
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Conclusions: Optimized culture conditions for maximizing yeast biomass production, determined in flask cultures was applicable at a larger scale. The highest yield values were attained in media containing relative low CMz concentrations supplemented with DAP and YE. YE would not be necessary if higher productivity is the aim.Significance and Impact of the Study: Cells of L. thermotolerans could be produced aerobically could be sustainably produced in a medium just containing cheap carbon, nitrogen and phosphorus sources. RSM allowed the fine tuning of cultural conditions.© 2012 The Authors Letters in Applied Microbi...
Source: Letters in Applied Microbiology - February 1, 2012 Category: Microbiology Authors: Roman PelinskiPatricia CerruttiMaría Lorena PonsoneSofía ChulzeMiguel Galvagno Source Type: research
Neck compartmentalization as the molecular basis for the different endocytic behaviour of Chs3 during budding or hyperpolarized growth in yeast cellsEmail this article to a colleague.
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ABSTRACTYeast cells normally grow by budding, but under certain specific conditions they are also able to grow in hyperpolarized forms reminiscent of hyphal growth. During vegetative growth, the synthesis of the septum that physically separates yeast cells during cytokinesis depends on the correct assembly of the septin ring. Septins and actin patches are assembled at the neck, forming two concentric rings where the actin patch ring occupies the external‐most part. This specific positioning defines a plasma membrane region at the neck from which other lateral membrane compartments are excluded. In this scenario, correct ...
Source: Molecular Microbiology - February 1, 2012 Category: Microbiology Authors: Carlos SacristanAbigail ReyesCesar Roncero Source Type: research
Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancerEmail this article to a colleague.
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A healthy human body contains at least tenfold more bacterial cells than human cells and the most abundant and diverse microbial community resides in the intestinal tract. Intestinal health is not only maintained by the human intestine itself and by dietary factors, but is also largely supported by this resident microbial community. Conversely, however, a large body of evidence supports a relationship between bacteria, bacterial activities and human colorectal cancer. Symbiosis in this multifaceted organ is thus crucial to maintain a healthy balance within the host‐diet‐microbiota triangle and accordingly, changes in a...
Source: Biological Reviews - February 1, 2012 Category: Biology Authors: Annemarie BoleijHarold Tjalsma Source Type: research
Med Sci Monit 2012; 18(2):CR93-104 "Dentigenous infectious foci – a risk factor of infective endocarditis"Email this article to a colleague.
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Conclusions: Among various dentigenous, infectious foci, the intradental foci appear to constitute a risk factor for infective endocarditis. (Source: Medical Science Monitor)
Source: Medical Science Monitor - February 1, 2012 Category: Research Tags: Original article Source Type: research
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We thank Chatterjee et al for their observations regarding the role of confocal microscopy in the diagnosis of infective keratitis. We would like to reiterate that our study was designed as a double-masked protocol with confocal microscopy performed first followed by microbiology evaluation, with both the evaluator studying the confocal scans and the microbiologist processing the slides and cultures masked to the results of the other's results. Only following the completion of the study and tabulation of the results, did the false positives and negatives emerge. Since the primary purpose of the study was to evaluate the s...
Source: Ophthalmology - February 1, 2012 Category: Opthalmology Authors: Pravin K. Vaddavalli, Prashant Garg, Virender S. Sangwan, Gullapalli N. Rao, Savitri Sharma, Ravi Thomas Tags: General Correspondence Source Type: research
Confocal MicroscopyEmail this article to a colleague.
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We have read with interest the article by Vaddavalli et al on the role of confocal microscopy in the diagnosis of infectious keratitis due to fungi and acanthamoeba. The authors found that about 10% of fungal keratitis could not be diagnosed with confocal microscopy, but do not suggest reasons for this. A possible explanation for false-negative results has been provided in another series published after Vaddavalli's article had been submitted, where it was suggested that hazy images and lack of patient cooperation may be possible causes of not detecting fungal filaments. Were the scans in this false-negative group of pati...
Source: Ophthalmology - February 1, 2012 Category: Opthalmology Authors: Samrat Chatterjee, Deesphikha Agrawal Tags: General Correspondence Source Type: research
Acute phase 99mTc-dimercaptosuccinic acid scan in infants with first episode of febrile urinary tract infection.Email this article to a colleague.
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CONCLUSIONS: Parenchymal damage found in a minority of infants with febrile UTI presented promptly to the hospital. Acute phase DMSA scan should be carried out only in selected patients. An abnormal acute DMSA scan is a moderate predictor for dilated VUR and its ability to exclude VUR is restricted.
PMID: 22282382 [PubMed - in process] (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - February 1, 2012 Category: Pediatrics Authors: Printza N, Farmaki E, Piretzi K, Arsos G, Kollios K, Papachristou F Tags: World J Pediatr Source Type: research
Does Vaginal Irrigation with Saline Solution in Women with Infectious Vaginitis Contribute to the Clinical and Microbiological Results of Antibiotic TherapyEmail this article to a colleague.
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Gynecol Obstet Invest (DOI:10.1159/000332396) (Source: Gynecologic and Obstetric Investigation)
Source: Gynecologic and Obstetric Investigation - January 31, 2012 Category: OBGYN Source Type: research
The use of rpoB sequence analysis in the differentiation of Mycobacterium abscessus and Mycobacterium chelonae: a critical judgement in Cystic Fibrosis?Email this article to a colleague.
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(Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - January 31, 2012 Category: Microbiology Authors: Cath ArnoldAnne BarrettLisa CrossJohn G. Magee Source Type: research
Domain organization of Legionella effector SetAEmail this article to a colleague.
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SummaryLegionella pneumophila is a human pathogen causing severe pneumonia called Legionnaires' disease. Multiple Legionella effectors are type IV‐secreted into the host cell to establish a specific vesicular compartment for pathogen replication. Recently it has been reported that the Legionella effector SetA shares sequence similarity with glycosyltransferases and interferes with vesicular trafficking of host cells (Heidtman et al., 2009, Cell Microbiol 11: 230). Here we show that SetA possesses glycohydrolase and mono‐O‐glucosyltransferase activity by using UDP‐glucose as a donor substrate. Whereas the catalytic ...
Source: Cellular Microbiology - January 31, 2012 Category: Microbiology Authors: Thomas JankKira E. BöhmerTina TzivelekidisCarsten SchwanYury BelyiKlaus Aktories Source Type: research
Calcium and ROS mediated defense responses in BY2 tobacco cells by non‐pathogenic Streptomyces spEmail this article to a colleague.
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Conclusions: New insights are thus provided into the interaction mechanisms between Streptomyces sp. and plants; Streptomyces sp. could be sensed by plant cells and through cytosolic Ca2+ changes and the generation of reactive oxygen species, defense responses were induced.Significance and Impact of Study: These induced defense responses appeared to participate to attenuating Pectobacterium‐induced diseases in plants. Thus Streptomyces sp. OE7 could to be a biocontrol agent against Pectobacterium sp..© No claim to US Government works. Journal of Applied Microbiology © 2012 The Society for Applied Microbiology (So...
Source: Journal of Applied Microbiology - January 31, 2012 Category: Microbiology Authors: Mohamed BazDaniel TranMohamed Kettani‐HalabiSalah Eddine SamriAbdelmounaim JamjariBernadette BiliguiPatrice MeimounHayat El‐Maarouf‐BouteauMarie GarmierPatrick SaindrenanMoulay Mustapha EnnajiMustapha BarakateFrançois Bouteau Source Type: research
The additive and synergistic antimicrobial effects of select frankincense and myrrh oils – a combination from the pharaonic pharmacopoeiaEmail this article to a colleague.
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Conclusions: The majority of interactions identified synergistic and additive effects, with strong synergism noted between B. papyrifera with C. myrrha.Significance and Impact of the Study: Frankincense and myrrh essential oils have been used in combination since 1500 BC, however, no antimicrobial investigations have been undertaken to confirm their effect in combination. This study validates the enhanced efficacy when used in combination against a selection of pathogens.© 2012 The Authors Letters in Applied Microbiology © 2012 The Society for Applied Microbiology (Source: Letters in Applied Microbiology)
Source: Letters in Applied Microbiology - January 31, 2012 Category: Microbiology Authors: S. de RapperS.F. Van VuurenG.P.P. KamatouA.M. ViljoenE. Dagne Source Type: research
An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflREmail this article to a colleague.
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SummaryThe eukaryotic bZIP transcription factors are critical players in organismal response to environmental challenges. In fungi, the production of secondary metabolites (SMs) is hypothesized as one of the responses to environmental insults, e.g. attack by fungivorous insects, yet little data to support this hypothesis exists. Here we establish a mechanism of bZIP regulation of SMs through RsmA, a recently discovered YAP‐like bZIP protein. RsmA greatly increases SM production by binding to two sites in the A. nidulans AflR promoter region, a C6 transcription factor known for activating production of the carcinogenic an...
Source: Molecular Microbiology - January 31, 2012 Category: Microbiology Authors: Wenbing YinSaori AmaikeDana J. WohlbachAudrey P.. GaschYi‐Ming ChiangClay C. WangJinWoo BokMarko RohlfsNancy P. Keller Source Type: research
ObituaryEmail this article to a colleague.
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(Source: FEMS Microbiology Letters)
Source: FEMS Microbiology Letters - January 31, 2012 Category: Microbiology Tags: Obituary Source Type: research
Association of CiaRH with resistance of Streptococcus mutans to antimicrobial peptides in biofilmsEmail this article to a colleague.
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In this study, we investigated the mechanism of resistance to cationic antimicrobial peptides (AMPs), which are innate immune factors in humans. Because dltA‐D (teichoic acid biosynthesis) was reported to affect the susceptibility to AMPs in other bacterial species, we evaluated the susceptibility of a dltC knockout mutant of S. mutans to the AMPs human beta‐defensin‐1 (hBD1), hBD2, hBD3 and LL37. The dltC mutant exhibited significantly increased susceptibility to AMPs. Regulation of dltC expression involved CiaRH, a two‐component system. Expression of dltC in the wild‐type strain was significantly increased in ...
Source: Oral Microbiology and Immunology - January 31, 2012 Category: Microbiology Authors: Y. MazdaM. Kawada‐MatsuoK. KanbaraY. OogaiY. ShibataY. YamashitaS. MiyawakiH. Komatsuzawa Source Type: research
Phytohormone production and colonization of canola (Brassica napus L.) roots by Pseudomonas fluorescens 6-8 under gnotobiotic conditionsEmail this article to a colleague.
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Canadian Journal of Microbiology, Volume 58, Issue 2, Page 170-178, February 2012. (Source: Canadian Journal of Microbiology)
Source: Canadian Journal of Microbiology - January 31, 2012 Category: Microbiology Tags: article Source Type: research
Correlation between plasma amino acid profiles and the various stages of hepatitis B infectionEmail this article to a colleague.
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In this study, we analyzed
the relationship between the amino acid profiles and varying clinical stages of HBV infection, and investigated their significance.
The plasma amino acid concentrations in 115 patients with HBV infection and 32 healthy donors were detected and analyzed,
and the main indicators of liver function were measured. Correlation analysis was performed between the amino acid profiles
(Fischer’s ratio, branched-chain amino acid to tyrosine ratio [BTR]) and the key indicators of liver function in patients
with HBV infection. Fisher’s ratio and the BTR of patients with HBV infection was found to dif...
Source: European Journal of Clinical Microbiology and Infectious Diseases - January 31, 2012 Category: Microbiology Tags: European Journal of Clinical Microbiology & Infectious Diseases Source Type: research
The Prevalence of Urogenital Infections in Pregnant Women Experiencing Preterm and Full-Term LaborEmail this article to a colleague.
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Conclusions. Urogenital infections were prevalent in women in preterm labor and full-term labor; however, significant differences between the groups were not observed. (Source: International Journal of Photoenergy)
Source: International Journal of Photoenergy - January 31, 2012 Category: Chemistry Source Type: research
