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TWiV 223: EEEV and the serpent
Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Vincent, Alan, and Kathy discuss new influenza virus NA inhibitors, detection of EEEV antibody and RNA in snakes, and replication of the coronavirus EMC in human airway epithelial cells. Links for this episode: International Women's Day 2013 Condit Dam, 6 weeks later (Vimeo) Influenza HA assay Covalent influenza NA inhibitors (ScienceExpress) Defective influenza HA mutants (Virology) New flu drug (BBC, e! Science) EEEV antibody, RNA in snakes (Am J Trop Med Hyg) EEEV (CDC) Zoonotic potential ...
Source: This Week in Virology - MP3 Edition - March 10, 2013 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

SEASON PREMIERE :: STANDUP2CANCER - Sep 11,2012
SURVIVOR SPOTLIGHT THOMAS LOVERRO Young Adult Survivor, Chorodial Melanoma Venture Investor, RRE Ventures ETHAN ZOHN Young Adult Survivor, Hodgkins Lymphoma Founder, Grassroot Soccer Celebrity Spokesperson, StandUp2Cancer TOM CHIODO Senior Vice President Entertainment Industry Foundation StandUp2Cancer DR. PHILLIP SHARP Nobel Prize-winning Molecular Biologist National Medal of Science Winner, 2006 Professor of Biology, McGovern Institute Scientific Advisory Council Chair, StandUp2Cancer standup2cancer | cancer research | young adult cancer | stupid cancer | entertainment industry foundation (Source: The Stupid Cancer Show - Blog Talk Radio)
Source: The Stupid Cancer Show - Blog Talk Radio - September 10, 2012 Category: Cancer & Oncology Authors: Stupid Cancer Show Tags: Health Source Type: podcasts

WHAT THE HELL IS A TELOMERE? - Jul 17,2012
SURVIVOR SPOTLIGHT LISA LAMBERT, J.D. Young Adult Survivor, Breast Cancer LARI WENZEL, PH.D. Professor of Medicine and Public Health University of California, Irvine EDWARD L NELSON, MD Associate Professor Medicine and Molecular Biology and Biochemistry University of California, Irvinemolecular medicine | genetics | young adult cancer | Affordable Care Act | university of california (Source: The Stupid Cancer Show - Blog Talk Radio)
Source: The Stupid Cancer Show - Blog Talk Radio - July 16, 2012 Category: Cancer & Oncology Authors: Stupid Cancer Show Tags: Health Source Type: podcasts

TWiV 175: More than one way to skin a virus
Vincent, Alan, and Matt discuss herpes simplex encephalitis in children with innate immune deficiency, and the local response to microneedle-based influenza skin immunization. Links for this episode: Herpes encephalitis in children with TRIF deficiency (J Clin Inv) Toll-like receptor and cytosolic pattern recognition receptors Skin responses to influenza microneedle vaccine (mBio) Microneedles Fluzone intradermal influenza vaccine QDot nanocrystal technology TWiV on Facebook Letters read on TWiV 175 Weekly Science Picks Matt - Phage and the Origins of Molecular ...
Source: This Week in Virology - MP3 Edition - March 18, 2012 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

William Wierda, MD, PhD talks about molecular and cellular biology and the role of microenvironment at the 14th International Workshop on Chronic Lymphocytic Leukemia IWCLL 2011
Author: imedex Added: 11/09/2011 (Source: Oncology Tube)
Source: Oncology Tube - November 9, 2011 Category: Cancer & Oncology Source Type: podcasts

Camera on Cancer Research: Using Mice Models to Fight Thyroid Cancer
Dr. Sheue-yann Cheng, Head of the Gene Regulation Section in the Laboratory of Molecular Biology, takes you into her lab where she researches the biology and molecular actions of thyroid hormone recep... Author: ncigov Added: 03/30/2011 (Source: Oncology Tube)
Source: Oncology Tube - March 30, 2011 Category: Cancer & Oncology Source Type: podcasts

Camera on Cancer Research: Unraveling the Molecular Mechanisms of Neuroblastoma
Dr. Carol Thiele, Head of the Cell and Molecular Biology Section in the Pediatric Oncology Branch, takes you into her lab where she researches the molecular mechanisms of neuroblastoma cells. Dr. Thie... Author: ncigov Added: 03/30/2011 (Source: Oncology Tube)
Source: Oncology Tube - March 30, 2011 Category: Cancer & Oncology Source Type: podcasts

Dr. Debu Tripathy MD discusses ER, PR and HER2-negative breast cancer (termed triple negative) is a particularly aggressive subtype for which targeted therapies are not effective.
While chemotherapy may be more effective in this subgroup, overall outcomes are worse. Molecular profiling and other biomarker studies suggest that the triple negative subtype is biologically distinc... Author: videoblog Added: 08/31/2010 (Source: Oncology Tube)
Source: Oncology Tube - August 31, 2010 Category: Cancer & Oncology Source Type: podcasts

A brief history of Neuroscience
Image via Wikipedia The Society for Neuroscience(SfN) was formed 40 years ago and to commemorate the occasion, the journal of Neuroscience has made some review articles open-access. They are written by leading luminaries in their filed and are somewhat scholarly- though I found some of them pretty accessible too. Two articles relate to reviewing memory research in the past 40 years and both are a pretty good read. The first is written by Larry Squire and gives you a broad overview of memory research. The second by Eric Kandel focuses more on the molecular aspects of memory formation- but is an excellent article and end...
Source: The Mouse Trap - October 29, 2009 Category: Psychiatrists and Psychologists Authors: sandygautam Tags: neuroscience default network memory Source Type: podcasts

Molecular Classification of Cancers of Unknown or Uncertain Primary
In this audio lecture, Dr. Anthony Greco discusses the latest findings in the biology and diagnosis of cancer of unknown or uncertain primary. (Source: MedscapeCME Gastroenterology Podcast)
Source: MedscapeCME Gastroenterology Podcast - July 31, 2009 Category: Gastroenterology Authors: MedscapeCME Source Type: podcasts

TWiV #20 - Hepatitis C virus
Vincent, Dick, Alan, and Matt Evans converse about TED, the Wakefield autism controversy, 99 rhinovirus sequences, Marburg in the USA, and hepatitis C virus. Links for this episode: A photographer catches Bill Gates’ mosquitoes Joe DeRisi at TED Dengue virus entry movie Sequencing of 99 rhinovirus serotype genomes Two views of the Wakefield autism controversy here and here Marburg virus comes to the USA Human occludin is a hepatitis C virus entry factor required for infection of mouse cells Science blog of the week: Not exactly rocket science by Ed Yong Science podcast pick of the week: Neuro...
Source: This Week in Virology - MP3 Edition - February 14, 2009 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Why Science Matters: a Year of the Science 2009 question
COPUS has been celebrating the Year Of Science 2009 and on the their main page their is a link to Why Science Matters that links to Alom Shaha's site Why is Science Important. Now we all know that EDGE asks an annual question to leading figures in academia/ intelligentsia and compiles their answers together and publishes as a book. That to me has always provided a rich perspective on contemporary matters. Alom and COPUS, in a similar vein, have asked a very topical question for the Year of Science 2009, which is as to Why Science Matters. This question they have put to prominent people in science education, research, wri...
Source: The Mouse Trap - January 29, 2009 Category: Psychiatrists and Psychologists Authors: Sandy G Source Type: podcasts

Perosnality and Neurotransmitters
Conclusion These findings implicate deficits in neuronal signaling via nitric oxide in moderation of prefrontal circuits underlying impulsivity-related behavior in humans. Now there does exist a relationship between NO and dopamine (but then which two neurotransmitter systems are not related) and that way I can still save my face by claiming that it is the dopamine that is finally mediating the impulsivity and not NO. There is evidence suggesting that nitric oxide (NO) may play an important role in dopamine (DA) cell death. NO may act as a neuroprotector or neurotoxic agent in dopamine neurons, depending on cell redox sta...
Source: The Mouse Trap - January 22, 2009 Category: Psychiatrists and Psychologists Authors: Sandy G Source Type: podcasts

A gene implicated in operant learning finally discovered
Till now, most of the research on learning at the molecular level or LTP/TLD has focused on classical conditioning paradigms. To my knowledge for the first time someone has started looking at whether , on the molecular level, classical conditioning , which works by associations between external stimuli, is differently encoded and implemented from operant learning , which depends on learning the reward contingencies of one's spontaneously generated behavior.Bjorn Brembs and colleagues have shown that the normal learning pathway implicated in classical conditioning, which involves Rugbata gene in fruit fly and works on adeny...
Source: The Mouse Trap - October 16, 2008 Category: Psychiatrists and Psychologists Tags: neuroscience learning behaviorism Source Type: podcasts

Chipping Away at Cancer
Clinical practice informs basic science research, and that research in turn informs clinical practice. In the field of oncology discoveries in molecular biology and genetics have revolutionized clinical care for patients with cancer. This series begins at the “bench” with Katherine Hyland and Joseph DeRisi describing genomic alterations that occur in cancer cells and how applications of genomic technologies use this information for diagnostic and therapeutic management. (Source: UCTV Presents: Health and Medicine)
Source: UCTV Presents: Health and Medicine - July 15, 2008 Category: Consumer Health Advice Source Type: podcasts

The eight-fold structure of evolutionary biology/ cultural evolution
Regulars readers of this blog will know that I am sold on the eight-fold developmental theory that assumes that there are eight stages of development/evolution of any feature and I have explored this extensively. Five of these lower stages are at a different level and the upper 3 at a different level explain the development of the same phenomenon. for a quick summary and links to my eight-fold fascination please see this the first paragraph of this post. So it is no surprise that I was fascinated when I discovered that evolutionary biology is conceptualized as eight subjects or methods of inquiry and they also follow a 5 +...
Source: The Mouse Trap - November 29, 2007 Category: Psychiatrists and Psychologists Tags: development evolution Source Type: podcasts

(One of) The gene for PPI discovered
In this study, we first performed a genetic dissection of mouse PPI using quantitative trait loci analysis, which detects chromosomal regions harboring causative genes. Further analyses including those of knockout mice, allowed us to identify one potential causative gene, Fabp7 (fatty acid binding protein 7, brain), a chaperon for the essential fatty acid docosahexaenoic acid. Human studies showed that the FABP7 gene is modestly associated with schizophrenia and that transcript expression levels are up-regulated in schizophrenic brains. From these results, we propose that a FABP7 protein-mediated disturbance of essential l...
Source: The Mouse Trap - November 15, 2007 Category: Psychiatrists and Psychologists Tags: schizophrenia Source Type: podcasts

Al B. Benson III, MD - State of the Science in Hepatocellular Carcinoma: Focus on Targeted Therapy
In this CME activity, experts in the treatment of hepatocellular carcinoma (HCC) discuss recent data on the efficacy and safety of emerging biologically driven agents in this condition. The recent data on staging systems and classification systems for HCC are also reviewed and the molecular targets in HCC are discussed. (Source: PeerView CME/CE Audio Podcast - Oncology)
Source: PeerView CME/CE Audio Podcast - Oncology - August 24, 2007 Category: Cancer & Oncology Authors: PeerView Press Tags: Science Source Type: podcasts

Al B. Benson III, MD - State of the Science in Hepatocellular Carcinoma: Focus on Targeted Therapy
In this CME activity, experts in the treatment of hepatocellular carcinoma (HCC) discuss recent data on the efficacy and safety of emerging biologically driven agents in this condition. The recent data on staging systems and classification systems for HCC are also reviewed and the molecular targets in HCC are discussed. (Source: PeerView CME/CE Video Podcast - Oncology)
Source: PeerView CME/CE Video Podcast - Oncology - August 24, 2007 Category: Cancer & Oncology Authors: PVI, PeerView Institute for Medical Education Tags: Science Source Type: podcasts

ASFH Glaucoma, Cataracts, and Perioperative Pressure
Guest: Hani Levkovitch-Verbin, MD Director, Sam Rothberg Ophthalmic Molecular Biology Lab Glaucoma Service Goldschleger Eye Institute Sheba Medical Center, Tel-Aviv University Tel-Hashomer, Israel (Source: As Seen From Here)
Source: As Seen From Here - August 4, 2007 Category: Opthalmology Authors: JYoungMD at gmail.com Source Type: podcasts

Ian Smith, MD, FRCP - Challenges and Opportunities in the Treatment of Breast Cancer in 2007 and Beyond
In this CME activity, experts provide an overview of recent progress, current challenges, and future opportunities in the treatment of breast cancer. The evolving role of molecular markers in making treatment decisions for patients with breast cancer is summarized. Evidence-based recommendations regarding treatment strategies for patients with breast cancer based on several different clinical case scenarios are discussed. Safety profiles of the taxanes and current options for management of febrile neutropenia in patients receiving taxane-based therapy are reviewed. Ongoing and new trials in the adjuvant and neoadjuvant set...
Source: PeerView CME/CE Video Podcast - Oncology - June 21, 2007 Category: Cancer & Oncology Authors: PeerView Press Tags: Science Source Type: podcasts

Ian Smith, MD, FRCP - Challenges and Opportunities in the Treatment of Breast Cancer in 2007 and Beyond
In this CME activity, experts provide an overview of recent progress, current challenges, and future opportunities in the treatment of breast cancer. The evolving role of molecular markers in making treatment decisions for patients with breast cancer is summarized. Evidence-based recommendations regarding treatment strategies for patients with breast cancer based on several different clinical case scenarios are discussed. Safety profiles of the taxanes and current options for management of febrile neutropenia in patients receiving taxane-based therapy are reviewed. Ongoing and new trials in the adjuvant and neoadjuvant set...
Source: PeerView CME/CE Audio Podcast - Oncology - June 21, 2007 Category: Cancer & Oncology Authors: PeerView Press Tags: Science Source Type: podcasts

Pursuing Ponce's Dream: Enabling the "Square-Wave Life Curve"
M.E. Johns, MD, Executive VP for Health Affairs at Emory University, explains why applying molecular biology to predicting life and health enables detection and prevention of disease. (Source: MedGenMed Weekly Editorials from Medscape.com)
Source: MedGenMed Weekly Editorials from Medscape.com - September 15, 2006 Category: Journals (General) Authors: Michael M.E. Johns, MD Source Type: podcasts